2000 ring closure reactions

ring closure reactionsO 0130

52 - 039Aldol Condensation versus Conjugate Addition: IntramolecularCyclization Using a Combination of Lewis Acid and 1,2-Diol. —The product ratio in the title reaction is investigated under different reactionconditions. In the cases where diols are used in combination with Tms-O-Tf, a mixture with mono- or diacetals is often observed. — (YAMADA,SATOSHI; SUEMUNE, HIROSHI; Chem. Pharm. Bull. 48 (2000) 8, 1171-1175; Grad. Sch. Pharm. Sci., Kyushu Univ., Higashi, Fukuoka 812, Japan; EN)

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