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 Characteristics  of  Life  Unit  

             

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Characteristics  of  Life  Front  Page         At the end of this unit, I will be progressing towards mastering the following NGSS standards: Engineering Practices

q ETS 1-1: Analyze a major global challenge to specify qualitative and quantitative criteria and constraints for solutions that account for societal needs and wants.

q ETS 1-2: Design a solution to a complex real-world problem by breaking it down into smaller, more manageable problems that can be solved through engineering.

q ETS 1-3: Evaluate a solution to a complex real-world problem based on prioritized criteria and trade-offs that account for a range of constraints, including cost, safety, reliability, and aesthetics as well as possible social, cultural, and environmental impacts.

Disciplinary Core Ideas q LS 1-1: Construct an explanation based on evidence for how the structure of DNA determines the

structure of proteins, which carry out the essential functions of life through systems of specialized cells.

q LS 1-2: Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms.

q LS 1-3: Plan and conduct an investigation to provide evidence that feedback mechanisms maintain homeostasis.

q LS 1-4: Use a model to illustrate the role of cellular division (mitosis) and differentiation in producing and maintaining complex organisms

q LS 1-6: Construct and revise an explanation based on evidence for how carbon, hydrogen, and oxygen from sugar molecules may combine with other elements to form amino acids and/or other large carbon-based molecules.

q LS 1-7: Use a model to illustrate that cellular respiration is a chemical process whereby the bonds of food molecules and oxygen molecules are broken and the bonds in new compounds are formed resulting in a net transfer of energy

q LS 2-4: Use mathematical representations to support claims for the cycling of matter and flow of energy among organisms in an ecosystem

Cross Cutting Concepts q Patterns: Observed patterns of forms and events guide organization and classification, and they

prompt questions about relationships and the factors that influence them. q Cause and effect: Mechanism and explanation. Events have causes, sometimes simple, sometimes

multifaceted. A major activity of science is investigating and explaining causal relationships and the mechanisms by which they are mediated. Such mechanisms can then be tested across given contexts and used to predict and explain events in new contexts.

q Scale, proportion, and quantity: In considering phenomena, it is critical to recognize what is relevant at different measures of size, time, and energy and to recognize how changes in scale, proportion, or quantity affect a system’s structure or performance.

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Characteristics  of  Life  Front  Page        Cross Cutting Concepts:

q Systems and system models: Defining the system under study—specifying its boundaries and making explicit a model of that system—provides tools for understanding and testing ideas that are applicable throughout science and engineering.

q Energy and matter: Flows, cycles, and conservation. Tracking fluxes of energy and matter into, out of, and within systems helps one understand the systems’ possibilities and limitations.

q Structure and function: The way in which an object or living thing is shaped and its substructure determine many of its properties and functions.

q Stability and change: For natural and built systems alike, conditions of stability and determinants of rates of change or evolution of a system are critical elements of study.

Roots, Prefixes and Suffixes I will understand are q Prefixes: Eu-, Pro-, micro-, cyto-, nucleo -, a-, bio-, different- q Suffixes: -um , -scope, -graph, -mass

The terms I can clearly define are q Scientific Method: Problem, Hypothesis, Independent Variable, Dependent Variable, Constants,

Negative and Positive Control Group, Experimental Group, Results, Empirical Data, Theoretical Data, Conclusion

q Systems: matter, energy, conservation of matter, conservation of energy q Levels of Organization: atoms, molecules, cell, tissue, organ, organ system, organism, population,

community, ecosystem, biomes, biosphere q Cell Theory: cell, cell theory, prokaryotic cell, eukaryotic cell q Cell Structure: nucleus, nuclear membrane, plasma membrane, DNA, chromatin, Lysosome,

Nucleolus, Vacuole, Mitochondria, Chloroplast, Centrosome, Centriole, Cytoplasm, Rough Endoplasmic Reticulum, Smooth Endoplasmic Reticulum, Free Ribosome, Attached Ribosome, Golgi Apparatus, Cell Wall

q Characteristic of Life: biotic, abiotic, homeostasis, differentiation, food web, producer, consumer, adaptation, evolution

q Microscopes: objectives, ocular lens, stage, diaphragm, fine adjustment knob, coarse adjustment knob, stage clips, body tube, cover slip

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Acrostic  Poem  for  the  Six  Common  Elements  of  Life  

   Carbon  Hydrogen  Oxygen  Nitrogen  Phosphorus  Sulfur  

     

C H O N P S

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Review:  How  to  Read  the  Periodic  Table    

   

Common  Core  Writing  Practice:  Using  the  infographic  above,  explain  how  to  read  the  periodic  table.  Consider  what  information  you  can  get  from  the  periodic  table,  and  explain  the  characteristics  of  another  element  listed  on  page  11,  other  than  Carbon.                                

                         

                         

                         

                         

                         

                         

                         

                         

                             

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My word part and definition

My partner’s word part and definition

Our Word Parts Combined

Translation

Bio-­‐‑  =     -­‐‑logy  =     Biology  

Building  Bio  logy  Words    

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     Introduction:      All  living  things,  no  matter  how  different  they  may  be,  share  common  characteristics.      Instructions:      Before  we  begin,  let’s  take  a  moment  to  explore  what  makes  something  alive.  Why  do  we  consider  plants  to  be  living  or  biotic,  but  a  set  of  keys  to  be  abiotic  or  not  alive?  What  characteristics  do  all  living  things  have  in  common?      In  this  activity,  you  will  rotate  around  the  room  and  examine  the  specimens  in  the  jars.  As  you  explore,  keep  a  list  of  characteristics  on  the  sheet  below  that  help  you  to  classify  the  organism  as  being  biotic  or  “alive.”    Be  prepared  to  share  your  ideas  with  the  class.        

What  Makes  Something  Alive?    

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 Now that the class brainstorm is complete, respond to the following prompt: What makes something alive? In other words, what characteristics do all living things share, despite their differences? Support your claim with concrete evidence and examples.    __________________________________________________________________________________________________________________________________________________________________________________________________________________________________________  __________________________________________________________________________________________________________________________________________________________________________________________________________________________________________  ____________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________    

What  Makes  Something  Alive?    

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Levels  of  Organization    Label  the  diagram  below.  After  labeling,  be  sure  to  define  levels,  as  you  see  fit.      

   

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Characteristics  of  Life  Notes  

What is the difference between the terms “abiotic” and “biotic”?

Abiotic = Biotic =

What are some characteristics of living things?

1. _____________________________________________________

2. _____________________________________________________

3. _____________________________________________________

4. _____________________________________________________

5. _____________________________________________________

6. _____________________________________________________

What are the two main classifications of cells?

1. ________________________: _______________  -­‐  __________

organisms that __________________________________________

_______________________________________________________

2. ________________________:-­‐  _______________________  or  

__________________________  organisms    ___________________________________  

___________________________________________________________________________  

What is the difference between a producer and consumer? Food webs

Producers: plants and other photosynthetic organisms that

__________________________________________________________

Consumers:  including  animals,  that  “_________”  or  _________________________  

________________________________________________________________________________  

Transfers of _______________ and _______________ through the ecosystem

can be shown through a diagram called a ____________ _____________.

What is homeostasis?

All organisms have _________________ _______________

__________________ which must be maintained to remain alive. This is

called _______________________________.

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All  Organisms  Use  Energy:  Food  Web      

                                                                                                                                                                                                                                                                                                                               

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Characteristics  of  Life  Notes   Explain how body temperature homeostasis is maintained (using your own words.

What are negative and positive feedback loops in homeostasis?

Negative feedback loop – a _____________ triggers a _____________ from

the body that eventually __________________________________.

Positive feedback loop – a _____________ triggers a _____________ from

the body that _______________________________________.

What is the definition of differentiation?

Differentiation is

If each human cell is genetically identical, why does differentiation occur? Explain in your own words after the class discussion.

What are adaptations? Changes that occur over time are called _________________________.

What is evolution? The inheritance of ______________________ over _________________.

What are the two ways an organism can reproduce?

1.

2.

Common Core Practice

Referring  to  the  food  web  diagram  on  the  opposite  page:  a)  Classify  the  producers  and  consumers  as  autotroph  or  heterotroph.    b)  What  is  missing  from  the  food  web  to  complete  the  cycle  with  regards  to  matter?  Add  this  to  your  diagram.    c)  Label  what  the  arrows  represent.    d)  After  labeling  the  diagram,  describe  one  food  chain  from  the  food  web  shown,  and  use  the  terms  producer,  primary  consumer,  secondary  and  tertiary  consumers  in  your  description.  Make  sure  that  you  are  defining  these  terms  as  you  use  them  to  clearly  explain  what  a  producer  or  consumer  actually  is.    e)  Explain  the  function  or  purpose  of  the  food  chain  using  the  terms  matter  and  energy.  

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Intentionally  Left  Blank  for  additional  brainstorming,  diagrams,  or  notes  

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Intentionally  Left  Blank  for  additional  brainstorming,  diagrams,  or  notes  

     

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Looking  at  Biomes  to  Study  Systems  and  Matter    

As  we  analyze  the  video  on  biomes  and  ecosystems,  we  will  define  systems.  In  the  space  below,  draw  a  conceptual  representation  of  a  system.    

                         If  an  organism  is  a  system,  where  is  matter  entering  and  leaving  this  system?  Label  the  diagram  below.    

   

                 

   

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Looking  at  Biomes  to  Study  Systems  and  Matter    

- Exactly,  what  is  a  system?  Try  to  define  it.    What  are  other  examples  of  systems?  

           - What  are  some  

abiotic  vs.  biotic  parts  within  these  systems?  How  do  they  interact?        

   - What  happens  to  

matter  within  a  system?    How  does  matter  move  through  the  abiotic  and  biotic  components?  

       - How  does  matter  

build  mass?  

       - Can  matter  within  

a  system  be  lost  or  destroyed?  (demo  after  the  video)  

   

 

 

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Organic  Building  Blocks    

1.  Producers,  or  autotrophs,  are  found  on  the  first  trophic  level  of  the  food  web.  What  organic  compound  do  they  produce  from  the  sun?          2.  Based  on  the  graphics  on  the  opposite  page,  which  three  elements  make  up  this  compound?          3.  You  will  be  given  time  to  do  some  quick  research  using  mobile  technology.    

a)  What  elements  are  found  in  lipids,  commonly  known  as  fats?      

b)  What  elements  are  found  in  amino  acids  and  proteins?      

c)  What  elements  are  found  in  nucleic  acids?      4.  Do  all  three  elements  found  in  carbohydrates  exist  in  lipids,  proteins  and  nucleic  acids?                5.  In  addition  to  these  three  basic  elements,  what  additional  element  do  you  need  to  build  amino  acids  and  proteins?            6.  What  element  separates  nucleic  acids  from  proteins?                              

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Organic  Building  Blocks    

     

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Organic  Building  Blocks    7.  Examine  the  ecosystem  on  the  opposite  page.    Consider  the  following  questions  as  we  discuss  this  image  as  a  class.  We  will  be  labeling  the  diagram,  per  your  teacher’s  instructions,  during  the  discussion.  a)  What  organisms  do  you  see  in  this  ecosystem?            b)  Why  do  organisms  need  to  interact  with  its  environment?              c)  How  do  producers  get  what  they  need  in  order  to  make  energy  in  the  form  of  sugar?  Consider  the  elements  that  need  to  be  combined  to  make  sugar.  Create  appropriate  labels  within  your  diagram.            d)  If  producers  need  to  make  proteins  and  nucleic  acids,  how  do  they  get  the  nitrogen,  sulfur,  and  phosphorus  they  need?  Use  mobile  technology  or  your  textbook  to  do  some  research  and  we  will  share  out  your  ideas  and  record  them  here.                      8.  Explain  how  a  food  web  can  shows  us  how  matter  cycles  through  an  ecosystem  to  support    life.                      

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At  the  end  of  your  journey  through  the  Nitrogen  Cycle,  complete  the  following:  

1.  Write  a  paragraph  about  your  trip  through  the  nitrogen  cycle.  Include  information  about  (1)  where  you  went,  and  (2)  how  you  got  to  each  destination.    

                         

                         

                         

                         

                         

                         

                         

                         

                         

                         

                         

                           

2. Do  some  research  and  look  up  the  Nitrogen  cycle.  Create  a  similar  diagram  specifically  documenting  your  journey  through  the  nitrogen  cycle,  based  on  this  activity.    

   

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Prokaryotic  Cell:    Cells  without  a  __________________________________________.  For  example  ______________________________________  They  are  _______________  in  size.    Label  the  following  image:                                      

Eukaryotic  Cell:    Cells  with  a  __________________________.  For  example  _________________________  and  _______________________  They  are  _______________  in  size    Label  the  following  image:    

       

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Cell  Theory      Who  was  Robert  Hooke?    

 

Who  coined  the  term  “nucleus”?  

   

 What  is  the  cell  theory?  

 1._____________________________________________________________________________________  

2.____________________________________________________________________________________  

______________________________________________________________________________________  

3.____________________________________________________________________________________  

______________________________________________________________________________________  

 Can  cells  be  seen  through  the  light  microscope?  

 

What  can  be  used  to  see  smaller  objects,  like  organelles?  

 

What  are  examples  of  eukaryotic  cells?    

What  size  are  they?      

 Summary:  (GIST  –  choose  5  -­‐10  of  the  most  important  terms  or  concepts  from  your  notes  to  explain  in  your  summary.  Your  summary  should  be  a  minimum  of  5  sentences)                              

                         

                         

                         

                         

                         

                         

                           

   

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Prokaryotic  vs.  Eukaryotic  Cells    Use  the  Venn  diagram  below  to  compare  and  contrast  eukaryotic  cells  and  prokaryotic  cells.          

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Common  Core  Practice:  Eukaryotic  vs.  Prokaryotic  Cells      

                               

   Which  cell  in  the  image  above  (A  or  B)  is  prokaryotic?  Which  is  eukaryotic?  Explain  and  give  evidence  to  support  your  answer.                              

                         

                         

                         

                         

                         

                         

                         

                         

                         

                         

                         

                         

                         

                           

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Directions:  Number  each  of  the  paragraphs.    Circle  all  the  scientists  that  were  involved  in  the  development  of  the  cell  theory,  and  highlight  their  contributions  and  what  they  learned.  Finally,  highlight  the  definition  of  a  “cell”  and  highlight  why  a  virus  is  NOT  considered  to  be  a  living  entity.      

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BIOCHEMISTRY  IN  PERSPECTIVE  Organelles  and  Human  Disease  

 Directions:  Read  the  article  below.  First,  number  the  paragraphs.  Then  circle  organelles,  circle  names  of  diseases  associated  with  organelles,  and  underline  functions  of  organelles,  disease  symptoms  or  complications  that  are  caused  by  the  organelle’s  dysfunction.  Use  this  reading  and  your  textbook  pages  182-­‐200  to  help  you  complete  the  foldable  on  the  following  pages.  

 What  is  the  role  of  biochemistry  in  modern  medicine?  

The   scientific   investigation   of   human   disease   is   only   two  hundred   years   old.   During   Europe’s   Age   of   Enlightenment  (seventeenth  and  eighteenth  centuries),  as  a  result  of  various  political   and   social   factors   combined  with   the   discoveries   of  Galileo,   Isaac   Newton,   Francis   Bacon,   René   Descartes,   and  other   scientists,   belief   systems   began   to   change.   Health  concepts  originating  with  Hippocrates  (fifth  century  BCE)  and  Galen  (second  century  CE)  had  been  unchallenged   for  over  a  thousand   years.   Humoral   medicine,   in   which   health   was  understood   in   terms   of   a   balance   of   the   “humors”   of   blood,  phlegm,  yellow  bile,  and  black  bile,  was  universally  accepted,  and   later   supplemented   by   medieval   superstition   (sickness  caused   by   divine   intervention).   Gradually,   however,   the  capacity   of   human   reason   to   understand   the   human   body  

gained  acceptance.  By  the  end  of  the  nineteenth  century,  previously  unimaginable  progress  toward  disease   diagnosis   and   treatment   had   been   made   because   of   discoveries   in   fields   ranging   from  anatomy,  cellular  pathology,  and  bacteriology  to  statistics.  Today,  human  disease  is  investigated  at  the  cellular  and  molecular  levels  because  of  breakthrough  work  performed  in  the  1940s  and  1950s.  Among   the  most   important  was   the  discovery  of  DNA  as   the   genetic  material   and   its   subsequent  structure   determination.   The   adaptation   of   the   electron  microscope  by  Keith   Porter   for   use  with  biological  specimens,  and  the  centrifugation  techniques  developed  by  George  Palade,  Albert  Claude,  and   Christian   DeDuve   made   the   identification   of   distinct   organelles   possible.   More   recent   work  utilizing   DNA   technology   has   profoundly   increased   our   understanding   of   the   molecular   basis   of  disease  and  vastly  improved  diagnostic  and  treatment  options.  

Organelles  can  contribute  to  a  disease  state   in  several  ways.  First,   the  organelle   itself  may  be   dysfunctional   either   because   it   contains   one   or   more   defective   biomolecules   that   impair  function,   or   because   it   has   been   damaged   by   exposure   to   harmful   substances   such   as   chemicals,  heavy  metals,  or  oxygen  radicals.  Second,  an  organelle  can,  through  its  normal  function,  exacerbate  damage  occurring  elsewhere  in  the  cell.  For  example,  as  we  have  seen,  misfolded  proteins  in  the  ER  can  trigger  apoptosis,  even  in  circumstances  in  which  it  is  counterproductive.  The  subsections  that  follow   describe   diseases   associated   with   the   endomembrane   system:   the   ER,   Golgi   apparatus,  vesicular  organelles,  the  nuclear  envelope,  and  the  plasma  membrane.  

THE   ENDOPLASMIC   RETICULUM.   The   ER   plays   such   a   central   role   in   the   synthesis   of  proteins  and   lipids   that  any  disturbance   in   its   function  can  have  serious  consequences.  Misfolded  proteins  coded  for  by  mutated  genes  and  ER  stress  cause  a  vast  number  of  diseases.  Cystic  fibrosis  (CF)   is   a   prominent   example   of   a   disease   caused   by  misfolded   proteins.   CF   is   an   ultimately   fatal  inherited  disorder   in  which   the   lack  of  a   specific   type  of  plasma  membrane  chloride  channel,   the  cystic   fibrosis   transmembrane   regulator   (CFTR),   causes   the   accumulation   of   a   thick   mucus   that  compromises  several  organs,  most  notably  the  lungs  and  pancreas.  The  misfolded  CFTR  protein      

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Function  

Plant  Cell  Foldable  

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becomes   trapped   within   the   ER   and   is   subsequently   degraded.   The   structural   and   functional  properties  of  CFTR  are  described  in  Chapter  11.  ER  stress,  induced  by  a  variety  of  conditions  such  as   protein   aggregation,   Ca2+   depletion,   glucose   deprivation,   or   fatty   acid   overload,   can   result   in  severe  cell  dysfunction  or  death.  It  is  an  important  feature  of  such  neurodegenerative  conditions  as  Alzheimer’s,  Huntington’s,  and  Parkinson’s  diseases,  as  well  as  heart  disease  and  diabetes.  

GOLGI  APPARATUS.  The  most  commonly  recognized  Golgi-­‐linked  diseases  are  a  group  of  15   congenital   disorders   of   glycosylation   (CDG).   (The   term   glycosylation   is   used   to   describe   the  covalent  linkage  of  carbohydrate  groups  to  polypeptide  or  lipid  molecules.)  Caused  by  mutations  in  genes   that   encode   glycosylation   enzymes   or   glycosylation-­‐linked   transport   proteins,   a   CDG   is  usually  lethal  by  the  age  of  2.  Symptoms  include  mental  retardation,  seizures,  and  liver  disease.  

NUCLEAR  ENVELOPE.  Many  of   the  diseases   attributed   to  defects   in   the  nuclear   envelope  occur  in  the  genes  that  code  for  lamin,  a  cytoskeletal  component  of  the  nuclear  lamina,  and  emerin,  an  inner  membrane  protein.  Examples  include  a  variety  of  diseases  of  skeletal  and  cardiac  muscle,  neurons,  and  tendons.  Progeria,  a  fatal  childhood  disease  characterized  by  premature  aging  of  the  musculoskeletal  and  cardiovascular  systems,  has  been  linked  to  a  specific  mutation  in  the  lamin  A  gene.  One  form  of  a  rare  hereditary  muscular  disease  called  Emery-­‐Dreifuss  muscular  dystrophy  is  caused  by  the  absence  or  mutation  of  the  gene  that  codes  for  emerin.  The  cellular  consequences  of  nuclear  envelope  deficits  include  a  fragile  nuclear  membrane,  altered  regulation  of  DNA  replication  and  transcription,  and  low  tolerance  to  mechanical  stress.  

VESICULAR  ORGANELLES.  Diseases  associated  with  vesicular  organelles  have  been  linked  to   lysosomes   and   peroxisomes.   The   lysosomal   storage   diseases   (LSD)   are   a   group   of   disorders  caused   by   the   absence   of   one   or   more   lysosomal   enzymes.   The   resulting   accumulation   of  undigested   molecules   causes   irreversible   cell   damage.   The   lipid   storage   diseases   Tay-­‐Sachs   and  Gaucher’s,  as  well  as  Pompe’s  disease  (glycogen  storage  disease  type  II),  are  caused  by  the  absence  of   a   single   enzyme.  Death  occurs   in   early   childhood.   In   I-­‐cell   disease,   the   import   of   all   lysosomal  enzymes   into   lysosomes   in   certain   organs   is   defective.   In   affected   cells,   the   enzymes   are   instead  secreted   into   the  extracellular  matrix.  Symptoms   include  mental  deterioration,  heart  disease,  and  respiratory  failure.  

PLASMA   MEMBRANE.   The   plasma   membrane   occupies   a   pivotal   position   in   the  endomembrane  system,  as   it   is  both  the  end  point  of   the  secretory  pathway  and  the  beginning  of  the  endocytic  pathway.  Consequently,  the  PM  plays  important  roles  in  a  wide  diversity  of  diseases.  Diseases  such  as  CF,  diabetes,  and  familial  hypercholesterolemia  (inherited  high  blood  cholesterol  levels)   are   directly   caused   by   defective   or   missing   membrane   proteins.   In   a   large   number   of  infectious  diseases,  microorganisms  invade  body  cells  in  endocytic  processes  initiated  by  binding  to  certain  plasma  membrane  receptors.  Examples  of  such  organisms  include  bacteria  such  as  Listeria  monocytogenes,  Salmonella  ,  and  Shigella  ,  and  some  viruses  (e.g.,  HIV).  For  viruses  like  HIV,  which  are   covered   in   an   “envelope”   derived   from   host   cell   membrane,   entry   is   gained   when   the   virus  binds   to   one   or   more   PM   receptors.   Following   fusion   of   the   host   cell   membrane,   and   the   viral  envelope,   the   viral   genome   enters   the   host   cell.   Other   diseases   are   caused  when   certain   bacteria  release   toxins   that   injure   cells.   Once   the   toxin   has   become  bound   to   a   specific   PM   receptor   on   a  target  cell,  either  a  pore  is  formed  through  which  the  toxic  protein  is  transferred  or  endocytosis  is  triggered.  Examples  include  cholera,  pertussis  (whooping  cough),  and  diphtheria  toxins.  

SUMMARY:   Biochemical   analysis   of   organelles   has   resulted   in   significant   progress   in   our  understanding  of  the  causes  of  many  human  diseases.    

   

   

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Animal  Cell  Foldable    

   

   

   Function  

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Labeling  Microscopes        (Use  reference  pages  24-­‐29  to  help  you  with  the  following  worksheets  and  notes  on  microscopes)    Compound  Light  Microscope    

 Dissecting  Microscope  

 

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Topic:  Care  and  Handling  of  the  Microscope    Ocular/Eyepiece   ONLY  use                                                                                                                                                                            to  clean  the  eyepiece.    

NEVER  use  paper  towels,  Kleenex,  toilet  paper,  etc.  The  magnification  of  the  eyepiece  is                                                    .  

Nosepiece   Use  only  the  nosepiece  to                                                                                                                                                                                    .          Do  NOT  change  the  magnification  by  grabbing  onto  the  objectives.  They  will  loosen,  fall  off,  and  break.  

Objectives    

There  are  three  objectives.          Low  power  –  __________  (short  one)          Medium  power  –  _________            High  power  –  _________  (biggest  one)    Always                                                                                                                                                                                                                                                        .  ONLY  use  lens  tissue  to  clean  the  objective  lens.  Do  not  touch  the  lens  with  your  fingers.  

How  do  you  calculate  the  total  magnification?  

 

Course  Adjustment    

This  is  the  focus  knob  that  you  must  use  first  to                                                                                                      .  

Fine  Adjustment   This  is  the  focus  knob  that  you  use                                                                    to                                                                                                  .  How  do  you  properly  focus?  

1. Start  with                      power  and  the  stage  down,  away  from  the  objective  lens.  2. Position  your  slide  in  the  middle  of  your  stage.  3. Slowly  turn  your                                                                                                                                                          knob  while  you  

look  through  your  eyepiece.  (the  image  should  become  roughly  clear  as  the  stage  moves  closer  to  the  lens.)  

4. Once  the  image  is  as  clear,  use  the                                                                                                                                knob  to  sharpen  the  focus.  

5. On                                                      power,  only  focus  with  the                                            adjustment  knob.  How  do  you  change  to  a  higher  power  and  focus?  

1. Make  sure  your  image  is  in  focus  at  LOW  power.  2. Re-­‐adjust  your  slide  so  your  image  is  in  the  middle.  (If  you  have  a  

pointer  in  your  field  of  view,  use  your  pointer  to  find  the  center  of  your  specimen).  Any  movement  of  the  object  also  shows  up  in  the  __________________________  way.  When  you  move  an  object  to  the  right,  it  appears  to  move  to  the                                              ,  and  when  you  move  it  up,  its  image  moves  down  

3. Without  touching  any  of  the  focus  knobs,  carefully  turn  the  nosepiece  to  change  the  power.  (On  high  power,  the  objective  might  touch  the  slide)  

4. On  MEDIUM  power,  refocus  CAREFULLY  with  the                                          adjustment,  then  the  fine  adjustment.  

5. On  HIGH  power,  refocus  ONLY  with  the                                                                  adjustment.  

How  do  you  carry  a  microscope?  

Support  the                                                    and  the                                                                            ,  using  two  hands.  

How  do  you  properly  store  a  microscope?  

Change  the  microscope  back  to                                                              power  and  lower  the  stage  Turn  off  the                                                                                  ,  and  wind  the  cord                                                                                            the  microscope.  

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Tips  for  Using  a  Compound  Light  Microscope    

 1. Multiply  the  _____________  X  ___________________  to  get  the  Total  Magnification.  

a. If  the  Ocular  is  10X,  and  the  Objective  Lens  is  10X,  what  is  the  total  magnification?      

b. If  the  Ocular  is  10X,  and  the  Objective  Lens  is  40X,  what  is  the  total  magnification?      

2. Always  start  with  your  objective  lens  at  the  ____________________________  power.  

3. Only  use  the  _______________  Focus  Knob  when  you  are  at  the  LOWEST  MAGNIFICATION!    

4. Move  the  slide  in  the  __________________  direction  of  what  you  want  to  see.  

5. When  you  are  done:  

a. Rotate  your  Nosepiece  to  the  ____________________  magnification.  

b. Drop  your  ________________  

c. Remove  and  _______________  your  slides  

 Use  your  notes  to  help  you  write  the  name  of  the  microscope  part  beside  its  function.      1.         supports  the  microscope  

 2.         used  to  change  which  objective  is  in  position  

 3.         provides  light  to  view  a  specimen  

 4.         controls  the  amount  of  light  reaching  the  stage  

 5.         supports  the  slide  

 6.         holds  slide  in  place  

 7.       also  called  eyepiece;  magnifies  ten  diameters  or  10X  

 8.       objective  used  to  locate  specimen  on  a  slide  

 9.           knob  that  brings  object  into  view    

10.         knob  that  brings  object  into  focus  

 

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Learning  How  to  View  a  Slide    

1. Select  a  slide  and  set  it  on  the  _____________  making  sure  the  specimen  is  centered  over  the  opening  in  the  stage.    Carefully  anchor  it  in  place  using  the  stage  _____________.  

2. Rotate  the  _______________________  to  center  the  lowest  power  objective  lens  (shortest  objective)  over  your  specimen.  

3. While  looking  through  the  eyepiece,  rotate  the  ___________________  adjustment  knob  to  get  your  specimen  in  view.    Use  the  small  __________  adjustment  knob  to  sharpen  the  image  and  make  it  clear.  

4. To  increase  magnification,  rotate  the  ______________________  to  center  the  next  largest  objective  lens  (middle-­‐sized  objective)  over  your  specimen.    You  may  need  to  use  the  ____________  adjustment  knob  to  sharpen  the  image.  

5. To  view  your  specimen  under  the  highest  magnification,  rotate  the  nosepiece  to  center  the  largest  objective  lens  (longest  objective)  over  your  specimen.    You  may  need  to  use  the  fine  adjustment  knob  to  sharpen  the  image.  

     

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Cell  Biodiversity  Lab    In  this  investigation,  you  will  observe  six  different  types  of  cells.      Consider  the  following  guiding  questions  as  you  draw:    

• Are  there  any  similarities  between  the  six  cells?  If  so,  how  are  they  similar?  • Are  there  any  differences?  If  so,  what  are  they  and  why?  • Are  the  cells  shaped  the  way  they  are  for  a  specific  reason?  What  might  those  reasons  

be?  • In  what  ways  might  the  shapes  of  the  cells  affect  the  way  it  functions  in  its  environment  

or  affect  its  role  within  a  multi-­‐cellular  organism?  • What  types  of  cells  are  these?  Can  you  classify  them  as  eukaryotic,  prokaryotic?  Are  they  

bacteria,  plant  cells,  animal  cells,  protists,  or  fungi?  • In  what  ways  are  these  cells  different  from  cells  you  have  studied  or  seen  in  the  past?  

Did  the  look  of  any  of  the  cells  surprise  you?  If  so,  in  what  way?    Did  you  observe  anything  that  may  challenge  what  you  thought  you  originally  knew  about  cells?  

Directions  for  drawing:    

q Carefully  draw  each  cell  with  as  much  detail  as  possible.  Do  not  include  structures  that  you   cannot   see.   Absolutely   no   chicken   scratch   is   allowed!   You   are   being   assessed   on  your  abilities  to  draw  what  you  observe.  

q You  do  not  need  to  draw  every  single  cell  you  see  on  a  slide.  You  only  need  to  draw  one  or  two  representation  of  the  type  of  cells  in  detail.  Choose  the  best  magnification.  High  power   is  not  necessarily   the  best  magnification  because   there   is   less   light.  Choose   the  magnification  that  gives  you  the  most  clarity,  whether  it  is  at  medium  or  high  power.  

q Label  all  known  structures  and  organelles.  If  you  do  not  know  the  structures,  it  is  okay  to  go  online  and  to  do  some  “research.”  Label  the  structures  based  on  what  you  learned  from  your   research.   Labels   are   always  written  and   read  horizontally,   and   leader   lines  never  intersect  one  another.    

q Use  colored  pencils  to  accurately  color  your  drawings.  Absolutely  no  ball-­‐point  pens  or  highlighters  allowed.    

q In   the   blank   space   provided   next   to   each   drawing,   job   down   observations   about   the  cells.  Use  the  guiding  questions  presented  above  as  a  guide  for  your  observations.  Bullet  point  notes  are  fine,  but  be  clear.    

 Conclusion  directions  to  be  completed  after  the  lab:  Look  over  the  guiding  questions  presented  to  you  at  the  start  of  this  lab.  Organize  your  thoughts  into  paragraphs  and  write  a  conclusion  to  this  activity,  using  the  guiding  questions  to  help  you.  This  is  an  inquiry  activity  designed  to  make  you  think  about  cells.    Some  of  your  own  observations  may  challenge  what  you  thought  you  originally  knew  about  cells.  You  may  not  necessarily  have  all  the  answers,  but  you  are  expected  to  make  inferences  and  claims.  You  are  expected  to  support  your  ideas  about  these  questions  based  on  the  evidence.  Evidence,  in  this  case,  should  mostly  come  from  your  own  observations,  drawings,  and  independent  research  you  may  have  done.  This  conclusion  will  be  turned  in  on  edmodo.    

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Cell  Biodiversity  Lab    

 Observations:  (use  guiding  questions  to  help  note  observations)            

                       

 Observations:  (use  guiding  questions  to  help  note  observations)                    

Title:                Magnification:          

Title:                Magnification:          

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Cell  Biodiversity  Lab    

 Observations:  (use  guiding  questions  to  help  note  observations)            

                         

 Observations:  (use  guiding  questions  to  help  note  observations)                    

Title:                Magnification:          

Title:                Magnification:          

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Cell  Biodiversity  Lab    

 Observations:  (use  guiding  questions  to  help  note  observations)            

                         

 Observations:  (use  guiding  questions  to  help  note  observations)                    

Title:                Magnification:          

Title:                Magnification:          

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Disappearing  Marine  Iguanas    Part  1:  

1. Using  the  map  and  the  minimal  knowledge  that  Liz  has  at  this  point,  propose  three  different  hypotheses  regarding  the  sudden  high  mortality  of  marine  iguanas.  Wait  for  a  class  discussion  before  proceeding  to  the  next  question.    

                                     

2. After  seeing  hypotheses  from  all  groups,  choose  the  hypothesis  that  seems  most  likely  to  your  group  and  determine  what  evidence  you  would  need  to  support  (or  refute)  it?    

   

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Part  2:    Examine  the  data  that  Liz  ran  into  while  researching  ENSO  in  Figures  1-­‐3.  Then  discuss  the  following  questions  in  your  groups.      

1. Given  what  you  know  at  this  point  about  marine  iguanas  and  the  abiotic  effects  of  enso,  develop  two  possible  directions  of  research  that  Liz  should  pursue  to  understand  exactly  why  the  iguanas  suffered  such  a  high  mortality.  Keep  in  mind  that  you  need  to  consider  indirect  effects.  While  environmental  temperature  does  change  metabolic  rates  of  ectotherms,  the  iguanas  are  exposed  to  a  wide  range  of  temperatures  as  they  feed  and  bask  on  the  lava.  Direct  mortality  in  response  to  a  temperature  change  of  a  couple  of  degrees  is  unlikely.  Wait  for  a  class  discussion  before  proceeding  to  the  next  question.  

               

       2. Choose  one  of  those  directions  of  research  and  determine  what  data  you  would  need  to  find  

to  support  your  ideas.    

           

3. Design  an  experiment  that  would  help  you  collect  the  data  you  have  identified  in  Question  2.  Identify  your  independent  and  dependent  variables  below.  Then  plan  out  your  investigation  on  the  following  pages,  using  the  template  provided.  a) Independent  Variable    (IV):  This  is  the  treatment,  or  the  variable  that  the  

experimenter  deliberately  changes,  to  test  the  dependent  variable.  Often  denoted  as  (x),  or  the  cause  of  the  change.    

   

b) Dependent  Variable  (DV):  the  change  that  is  observed  and  recorded  as  data  as  a  result  of  the  independent  variable.  Often  denoted  as  (y),  or  the  effect  of  the  change.    

 

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Problem  (or  the  guiding  question…)  

Null  Hypothesis:  The  null  hypothesis  refers  to  a  general  statement  or  default  position  that  there  is  no  relationship  between  two  measured  phenomena.  State  the  null  hypothesis  below.    Hypothesis  2:  If  there  is  a  relationship  between  two  measured  phenomena,  what  hypothesis  would  this  be?  State  the  hypothesis  below:  

Null  Hypothesis                    Hypothesis  2

If…   If…  

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The  Test  

I approve of this investigation: Date    

What data will you collect? How will you analyze the data? What will be your control group? Is this a negative or positive control? What are your constants? Write out the procedure. Circle the materials within the procedure.

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Part  3:  Liz  took  a  deep  breath;  that  paper  wasn’t  going  to  write  itself.  With  only  a  few  days  left  until  the  deadline  it  was  time  for  her  to  get  going.  “So  now,  what  do  these  studies  tell  me  about  enso  and  marine  iguanas?”    

Discuss  the  following  questions  with  your  group,  and  we  will  share  out  your  ideas.  

1. What  conclusions  do  you  think  Liz  made  about  the  cause  of  population  declines  in  marine  iguanas?      

 

 

 

 

 

 

 

 

 

2. Is  it  reasonable  to  assume  that  the  data  from  the  1982–1983  and  1991–1992  enso  events  are  representative  of  what  happened  in  the  later  1997–1998  event?  Why  or  why  not?      

 

 

 

 

 

 

 

 

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3. Do  we  have  what  we  need  or  do  we  need  additional  information?  Is  there  a  potential  problem  with  one  or  more  of  the  studies?      

   

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Characteristics  of  Life  Unit  Study  Guide    Part  1:  Review  –  here  is  a  checklist  of  topics…  Complete  each  of  the  following  tasks  to  help  yourself  prepare  for  the  upcoming  test.      

q Do  you  know  the  six  characteristics  of  life  and  the  theory  about  the  makeup  of  living  things?  

q Can  you  recite  the  six  common  elements  of  life  and  determine  which  elements  make  up  large  molecules  such  as  carbohydrates  (sugars),  lipids  (fats),  proteins,  and  nucleic  acids?  

q Do  you  know  the  levels  of  organization  in  the  correct  order?  Make  an  acrostic  poem,  a  song,  or  another  memory  device  to  help  you  remember  the  correct  order.    

q Can  you  clearly  define  the  difference  between  a  population,  community,  and  ecosystem?    q Can  you  determine  how  matter  flows  through  the  ecosystem?  q Do  you  know  the  law  of  conservation  of  matter  and  what  it  means?  q Can  you  explain  homeostasis  and  how  it  is  controlled?  q Can  you  explain  differentiation  and  why  it  is  necessary  in  multicellular  organisms?  q Go  back  to  your  Cornell  notes  for  this  unit.  Cover  the  right  side  of  the  page  and  attempt  to  

answer  the  questions  on  the  left  side.  Review  any  areas  where  you  struggled  or  needed  to  look  at  your  notes  for  information.    

q Revisit  your  Venn  diagram  on  prokaryotic  vs.  eukaryotic  cell.  Can  you  explain  the  different  classifications?    

q Study  the  parts  of  a  microscope.  Come  in  during  F.I.R.E.  to  practice  labeling  the  parts.  q How  is  your  writing?  Can  you  support  your  ideas  and  claims  with  evidence  from  reading  

material,  diagram,  research,  and  observations?  q Can  you  design  a  valid  experiment  with  proper  controls,  constraints,  and  reliable  data?  Can  

you  use  inductive  reasoning  to  analyze/interpret  data  and  deductive  reasoning  to  formulate  a  conclusion?    

   

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Part  2:  Practice  After  reviewing,  attempt  the  following  questions.  Try  to  complete  as  much  as  possible  without  looking  back  at  your  notes.  If  you  cannot  answer  a  question,  look  to  your  notes  for  help.  Mark  any  topics  that  required  you  to  look  back  at  your  notes  and  focus  on  these  areas  when  you  study.    

 1. List  the  six  characteristics  of  life:  

             

2. Create  a  flow  chart  in  the  space  below  showing  the  complex  organization  pattern  of  living  things  from  largest  (biosphere)  to  smallest  (atom).    

 3. Which  level  in  the  above  flow  chart  is  the  smallest  level  for  living  things?  

       

4. What  is  homeostasis?  Define  it  and  give  an  example.    

       

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 5. Design  an  experiment  that  demonstrates  that  feedback  mechanisms  maintain  homeostasis  

in  the  eye,  in  response  to  light.    

a. Identify  the  Guiding  Question  

   

b. Null  Hypothesis    

 c. Hypothesis  

   

d. Independent  Variable  (Experimental  Treatments)  

     

e. Dependent  Variable  

     

f. Control  Group  

   

g. Constants  

     

h. Procedure  

                         

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 6. Draw  a  food  chain  to  show  how  matter  and  energy  moves  through  the  ecosystem.  Label  all  

of  the  trophic  levels  within  your  food  chain.  (producer,  primary  consumer,  etc.)  Try  to  have  at  least  four  links  in  your  food  chain.  Make  sure  the  cycle  of  matter  within  the  food  chain  is  finished  with  decomposers.  Include  where  matter  and  essential  elements  for  life  can  enter  your  system.  (CO2,  O2.  Nitrogen,  Phosphorus,  Sulfur,  H2O)  –  If  you  are  not  sure  where  these  elements  enter  the  system,  it  is  okay  to  look  up  this  information  in  your  textbook  or  on  the  internet.    

                                   

7. Diagram  the  basic  differences  between  a  prokaryotic  and  eukaryotic  cell.  Think  about  the  relative  sizes  of  each  type  of  cell,  and  draw  them  to  scale.  Label  the  characteristic  features  in  each  cell.  

                 

     

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8. Practice  defending  your  idea  on  this  statement  through  your  writing.  It  is  okay  to  use  your  lab,  textbook,  or  any  source  to  support  your  claim.  Try  to  cite  your  source  for  credibility.    For  example,  you  can  cite  sources  like  this:  according  to  National  Geographic;  based  on  observations  made  on  the  microscope  lab;  the  Biology  textbook  states,  etc.    Have  at  least  three  pieces  of  supporting  evidence.  As  you  are  writing,  make  sure  you  are  clear.  Define  terms,  as  necessary,  to  demonstrate  knowledge.  For  example,  if  you  are  talking  about  prokaryotic  cells,  it  is  probably  important  to  define  the  word  “prokaryotic”  first.  Use  additional  paper,  if  necessary.    

All  animal  cells  are  round.  True  or  False?  

                       

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9. The  diagram  below  demonstrates  cell  differentiation.  First,  define  differentiation.  Then  use  your  diagram  to  explain  how  a  neuron  (nerve  cell)  or  an  epithelial  cell  can  differentiate    from  the  same  cell.  (You  are  using  your  picture,  in  this  case,  for  evidence  and  contextual  clues)  

   

       

     

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10. What  are  two  ways  that  cells  can  reproduce?  Define  the  two  ways.  

   

11. Which  part  of  the  microscope  is  responsible  for...?    

a. Holding  a  slide  in  place?      

b. Adjusting  the  focus?  

 c. Controlling  the  amount  of  light?  

   

12. How  do  you  calculate  magnification?  Show  an  example  calculation.    

     

13. Label  the  parts  of  the  microscope  below:  

 

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Eukaryotic  vs.  Prokaryotic  Cell  Unit  Concept  Cards  

(see  Reference  pages  12  and  13  for  directions)        

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Characteristics  of  Life  Unit  Concept  Map  (see  Reference  pages  18-­‐19  for  directions)  

     

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Cell  Unit  Parent/  Significant  Adult  Review  Page    

Student  Portion    Name                 Period  

 Unit  Summary:  Write  a  summary  of  the  past  unit  using  5-­‐10  sentences.  Use  your  concept  map  to  guide  your  writing.  Your  summary  should  explain  concepts  you  learned  in  an  integrated  manner.    A  summary  is  not  a  simple  list  of  topics  covered  in  this  unit.    See  Reference  Page  22,  for  an  example  of  a  well-­‐written  summary.                                                    What  is  your  favorite  assignment  in  this  unit  and  why:              

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Adult  Portion    Dear  Parent/  Significant  Adult:  This  Interactive  Notebook  represents  your  student’s  learning  to  date  and  should  contain  the  work  your  student  has  completed.  Please  take  some  time  to  look  at  the  unit  your  student  just  completed,  read  his/  her  reflection  and  respond  to  the  following      Ask  your  child  to  defend  why  a  pencil  sharpener  is  not  a  living  organism.  Record  his/her  thoughts  below.                                          Please  explain  if  your  child  has  had  any  science  background,  prior  to  Foothill,  and  what  assignment  in  this  unit  was  the  most  challenging  for  your  child,  as  he/she  transitions  from  middle  school.                                  Parent/  Significant  Adult  Signature:  

 

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