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Chapter 10
Licit and Illicit Drug Use
Defining AddictionsDefining Addictions
• patterned use and patterned use and dependency on mind or dependency on mind or mood altering substancesmood altering substances
• interferes with interferes with academic/workacademic/work
• familyfamily• interpersonal relationshipsinterpersonal relationships• social/economic functioningsocial/economic functioning• physical/mental healthphysical/mental health
The Physiology of Addiction- mental, emotional, and Behavioural function occur due to mental, emotional, and Behavioural function occur due to
biochemical reactions between nerve cells and thebiochemical reactions between nerve cells and the bodybody
• Neurotransmitters - Neurotransmitters - biochemical messengers that biochemical messengers that exert influence at specific exert influence at specific receptor cites on nerve cellsreceptor cites on nerve cells
• drugs can alter these cites - drugs can alter these cites - change moods / fill insufficient change moods / fill insufficient amountsamounts
• Tolerance - over time needing Tolerance - over time needing greater amounts of substancegreater amounts of substance
The Addictive ProcessThe Addictive Process
• avoid unpleasant feeling avoid unpleasant feeling or situationor situation
• nurturing through nurturing through avoidanceavoidance
• coping skills not coping skills not developeddeveloped
• addiction increasesaddiction increases• relationships deterioraterelationships deteriorate
Signs of AddictionFour Common Symptoms
Compulsion / ObsessionCompulsion / Obsession
excessive preoccupation with the behaviour / overwhelming need to perform it
Loss of ControlLoss of Control - inability to predict consequences of behaviour as healthy or damaging
Negative Consequences - Negative Consequences - physical damage, physical damage, legal trouble, financial, academic failurelegal trouble, financial, academic failure
Denial Denial - inability to perceive behaviour is self-destructive
Types of Drugsstimulate / depress / hallucinate
• prescription drugsprescription drugs• OCT preparationsOCT preparations• recreational recreational
substancessubstances• herbal preparationsherbal preparations• illicit drugsillicit drugs
Psychoactive drugsPsychoactive drugs• Mood / behaviour Mood / behaviour
alteringaltering
Routes Of Administration of Drugs …how the drug is taken into the body
• Oral Injestion - mouthOral Injestion - mouth• Injection - hupodermic Injection - hupodermic
needleneedle• Intravenous injection - Intravenous injection -
veinvein• Intramuscular injection Intramuscular injection
- muscles- muscles• Subcutanious injection- Subcutanious injection-
fat below skinfat below skin
Routes Of Administration of Drugs …how the drug is taken into the body
• Inhalation - nostrilsInhalation - nostrils• Suppositories - Suppositories -
inserted into anus or inserted into anus or vagina - melt at body vagina - melt at body temp.temp.
• Inunction - through Inunction - through skinskin
Drug Use, Abuse, and Interactions
• drug misuse - using drug misuse - using drug for other reasons drug for other reasons than intendedthan intended
• drug abuse - excessive drug abuse - excessive useuse
• Environmental Environmental factors- main-effect & factors- main-effect & side-effectside-effect
• Set and SettingSet and Setting
Individual Response to Psychoactive DrugsSET & SETTING
• SetSet - how the person thinks……. Mindset - while under the influence
• physical, emotional and social factors / work together or against to influence the drug’s effect
• SettingSetting - external factors / drug taken in a quiet place vs. a loud party
Drug Interactions
• Polydrug use - multiple medication / illicit drugs - simultaneously
• Synergism - two or more drugs taken….produce different effect
• Antagonism - two or more drugs working on same receptor site
Drug Interactions
• Inhibition - drugs compete for same receptor site / reduce effectiveness of each one
• Intolerance - two or more drugs produce uncomfortable symptoms
• Cross - tolerance - developed tolerance to one drug that reduces effectiveness of similar drug
Prescription DrugsTypes
• Antibiotics - fight bacteria / infections
• Analgesics - pain relievers
• Prostaglandin inhibitors - inhibit production & release / associated with pain from arthritis+ menstruation
• Sedatives - CNS - Induces sleep / reduces anxiety
Prescription DrugsTypes!!!
• Tranquilizers - CNS depressants / relax body + calm anxiety
• Antidepressants - used to treat clinically diagnosed depression
• Amphetamines - stimulants / associated dangers
• Rebound effects - withdrawal from stimulants / serious / depression, nausea, violence
• Generic Drugs - chemical names not brand names
Over-the-Counter (OCT) Drugs
Nonprescription Drugs
• self-diagnoses / self-treatment
• Safe? Abuse? Harmful!!!!!!
Types:
• Analgesic / pain killers / use common + wide spread
• Cold, Cough, Allergy, and Asthma Relievers - Don’t cure / reduce symptoms
• Stimulants - used to keep awake! All night paper writing - students
Over-the-Counter (OTC) Drugs
• Sleeping Aids and Relaxants - induce sleepy/ drowsy feeling
• Dieting Aids - “appetite suppressant” - a stimulant which can be dangerous
• Sympathomimetics - induce stress reaction
Over-the-Counter (OCT) Drugs
Laxatives - softens stool +
relieves constipation • use for weight loss /
ineffective
Diuretics - promotes increased urination - for weight loss ineffective / water replenished and creates chemical imbalances
Illicit Drugs…… illegal to possess, produce or sell
• Although illegal widely used and Although illegal widely used and remains a problem in Canadaremains a problem in Canada
• Controlled SubstancesControlled Substances• Cocaine - powerful stimulant - Cocaine - powerful stimulant -
leaves from South American leaves from South American Shrub -3.8% casual use 1.4% Shrub -3.8% casual use 1.4% regular in Canadaregular in Canada
• Effects…….Effects…….• Serious results to physical, mental Serious results to physical, mental
and social healthand social health
Illicit Drugs…… illegal to possess, produce or sell
• Amphetamines - addictive stimulant that improve alertness, lessen fatigue and improve mood
• Marijuana - chopped leaves + flowers from cannabis - heightens reactions to environmental stimuli
Illicit Drugs…… illegal to possess, produce or sell
• Hashish - thick / sticky resin from cannabis plant
• Marijuana and Medicine - used to reduce nausea in cancer patients and to reduce eye pressure for glaucoma
Illicit Drugs…… illegal to possess, produce or sell
• opiatesopiates• narcotics (Greek for Stupor) narcotics (Greek for Stupor)
are derived from the parent are derived from the parent drug opiumdrug opium
• opium - made from milky opium - made from milky juice of poppy seedsjuice of poppy seeds
• morphine - pain relievermorphine - pain reliever• codeine - found in cough codeine - found in cough
medicine and painkillersmedicine and painkillers
Illicit Drugs…… illegal to possess, produce or sell
• Heroin - illegally Heroin - illegally manufactured from manufactured from morphine / injected into blood morphine / injected into blood streamstream
• Methadone Maintenance -Methadone Maintenance -treatment for people addicted treatment for people addicted to opiates - synthetically to opiates - synthetically producedproduced
Illicit Drugs…… illegal to possess, produce or sell
Psychedelics - distort sensory Psychedelics - distort sensory informationinformation
Reticular formation - relay Reticular formation - relay information to other parts of information to other parts of the brainthe brain
Synesthesia - sensory messages Synesthesia - sensory messages are misinterpretedare misinterpreted
Hallucinations - images perceived Hallucinations - images perceived as real but are notas real but are not
Illicit Drugs…… illegal to possess, produce or sell
• Lysergic acid diethylamide Lysergic acid diethylamide (LSD) - causes sensory (LSD) - causes sensory disruptions - “ACID”disruptions - “ACID”
• Mescaline - hallucinogenic drug Mescaline - hallucinogenic drug
• Peyote - cactus / has parts that Peyote - cactus / has parts that create hallucinogenic effectscreate hallucinogenic effects
• Psilocybin - chemical in Psilocybin - chemical in mushroom causes mushroom causes hallucinogenic effectshallucinogenic effects
Designer Drugs - Synthetically produced drug / Similar effects to Illicit Drugs
Manufactured byManufactured by
underground chemistsunderground chemists
Three types availableThree types available
analoguesanalogues• phencyclidine (PCP)• amphetamine• methamphetamine
Inhalants - sniffed or inhaled
Amyl Nitrate - “poppers or rush”• a vasodilator - used to enhance
orgasm / fainting, dizziness, warmth, skin flushing
Nitrous Oxide - “laughing gas” creates a state of euphoria / floating / illusions
• overdose - unconsciousness, coma or death
Steroids - artificial forms of testosterone / promotes muscle growth + strength
• Ergogenic aid• Athletic performance • Recreational use widespread to look a
certain way- BIG!• Adverse effects - mood swings (“roid
rage”), acne, liver tumors, higher cholesterol levels, hypertension,kidney disease, immune system weakening
• HIV - shared needles!!!
Steroids - artificial forms of testosterone / promotes muscle growth + strength
• Women - masculine Women - masculine traits / lowered voice, traits / lowered voice, increased facial + increased facial + body hair , male body hair , male pattern baldness, pattern baldness, enlarged clitoris, enlarged clitoris, decreased breast size, decreased breast size, changes to menstrual changes to menstrual cyclecycle
Steroids - artificial forms of testosterone / promotes muscle growth + strength
• Men - shuts down Men - shuts down body’s natural body’s natural production of production of testosteronetestosterone
• develop breastsdevelop breasts• testicles atrophytesticles atrophy
• Is it Worth it????Is it Worth it????
Drugs: Are They Worth IT?Drugs: Are They Worth IT?
• The impact to society is The impact to society is devastating!!!!!devastating!!!!!
• CrimeCrime• RelationshipsRelationships• School / WorkSchool / Work• LifestyleLifestyle• HealthHealth• FunFun• DenialDenial• What is the REAL What is the REAL
problem??problem??