Central Ohio Bariatrics Presentation

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    CLINICALLY SEVERE

    OBESITY

    TIMOTHY CUSTER M.D., F.A.C.S

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    WHAT IS MORBID

    OBESITY?

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    BMI CHART

    Do You Know Your Own BMI?

    5'4"5'4"

    Height

    Height

    Weight (lbs)Weight (lbs)

    5'25'2""

    5'0"5'0"

    5'10"5'10"

    5'8"5'8"

    5'6"5'6"

    6'0"6'0"

    6'2"6'2"

    120120130130 150150 160160170170180180190190 200200210210220220 230230240240250250140140 260260 2702702828

    00

    2929

    00

    300300

    6'4"6'4"

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    Definitions

    Category BMI lbs overweight % US pop

    Normal 25 0 30%

    Overweight >25 0-35 30%

    Obese >30 >35 35%

    Morbidly Obese >40 >80 - 100 5% (15 million)

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    Morbid Obesity a disease Clinically severe obesity = a point at

    which obesity becomes an independent

    disease processand medicalconditions occur as a result

    this occures at about 100 lbs

    over ideal body weight or BMI 40

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    OBESITY IS A WORLDWIDE EPIDEMIC

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    Consequences of Obesity

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    Consequences of Obesity

    Type II Diabetes 30% Hypertension 50% CAD/ CHF 20% Hyperlipidemia 50% Respiratory Insuff. 70%

    - Sleep Apnea

    - Obesity Hypovent Synd

    - Asthma

    Intra-abdominal HTN- GERD

    - Stress Incontinence- Venous Insufficiency

    - DVT / PE

    - Hernias

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    Consequences of Obesity

    Gallstones Arthritis 90%

    Infertility Hepatosteatosis

    Chronic SkinInfections

    Pseudotumor Cerebri

    Cancer - 2-3x higher- Breast

    - Endometrial/Cervical- Colon

    - Prostate

    Depression Social Rejection

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    Clinically severe obesity

    Risk of not Having Surgery

    0

    1

    2

    3

    4

    20 25 30 35 40

    MortalityRatio

    0

    1

    2

    3

    4

    20 25 30 35 40

    MortalityRatio

    Increasing BMI

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    Mortality of Obesity

    Shortens life by 8 yrs for women and 15years for men

    Only one in seven with severe obesityreach a normal life span (77y)

    Carries a higher mortality than mostcancers

    Current generation is the first to haveshorter life expectancy than their parentsin 100 yrs

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    OBESITY EPIDEMIC

    Obesity responsible for >$100 billion inmedical costs per yr

    US was first in life span in 1900, nowLAST among developed nations Current generation predicted to have 1/3

    chance of developing DM

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    Consequences - Mortality

    Taken together, the diseases associated

    with morbid obesity markedly reduce theodds of attaining an average life span and

    raise annual mortality tenfold or more.

    American College of Surgeons, Recommendations for facilitiesperforming bariatric surgery, ST-34, Bull Am Col Surg, 2000;85:

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    Consequences - Mortality

    >300,000 people die each year secondary tocomplications of obesity, making it our

    2ndleading cause of preventable death

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    IV. Treatment of Obesity

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    Medical Treatment

    The bottom Line:All Non-surgical weight loss attempts achieveat best modest and short term success in the

    morbidly obese population, with about 10%wt loss, and regain in about 95% within twoyears

    ANYTHING LESS THAN A RADICALANDPERMANENT TRANSFORMATION WILLRESULT IN FAILURE TO TREAT MORBIDOBESITY

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    Medical Weight Loss

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    1991 Concensus Conference on

    Obesity Medical Therapy is Rarely successful Those who fail medical therapy should be

    treated surgically

    Criteria for surgical therapy:- BMI > 40

    - BMI > 35 with significant comorbidities

    - failed attempts at medical wt lossProcedures recommended = VBG and GBP

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    Surgical Options

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    Ruox en Y Gastric Bypass

    First developed in the1970s

    Procedure of choice inthe United States

    Best wt loss with thelowest side effects

    60 - 80% EWL in 12 - 18mo (90% lose 70%)

    Maintained up to 15 yrspost op

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    Gastric Bypass

    Q : How does the GBP effect wt loss?

    A : Four mechanisms

    1. Restriction2. Malabsorption

    3. Dumping Syndrome

    4. Hormonal Changes

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    The Roux-en-Y Procedure

    In the Roux-en-YBypass procedure, asmall pouch

    is formed along thelesser curve, excludingthe fundus

    The fundus is the partthat can stretch out

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    The Roux-en-Y Procedure

    The small intestine isdivided about 20-50

    cm beyond the lig oftrietz (beginning pt ofthe jejunum)

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    The Roux-en-Y Procedure

    The small intestine(B), is brought up tothe gastric pouch andthese are attached

    The bilio-pancreaticlimb (A) is hooked upto the Roux limb (B)100 to 150 cm fromthe pouch

    The biliopancreaticlimb delivers the bileand enzymes, so foodin the roux limb ispoorly digested

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    Dumping

    The Roux limb does

    not handle sugar welland therefore eatingsweets will causenausea, cramping

    and diarrhea

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    Decreased Hunger

    Ghrelin is a hormone that stimulates appetite Ghrelin levels are seen to drop within 24 hrs of surgery

    and stay depressed Result = Im just not hungry Not clear why this occurs

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    Benefits of GBP

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    Roux-en-Y

    Open Procedure More pain Longer hosp stay Longer return to work Wound complications

    - seroma (15%)

    - infection (

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    Laparoscopic Roux-en Y

    Less pain Shorter stay Less blood loss Faster return to

    work

    Technically morechallenging

    More internalhernias

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    Restrictive Surgery

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    LAP BAND

    Mechanism purely restrictive(nodecreased appetite, dumping, ormalabsorbtion)

    Injecting saline tightens the opening,decreasing flow out of the pouch

    Adjustments made based on symptoms,wt loss, about every 4 weeks for firstseveral months

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    LAP BAND

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    Lap Band Advantages

    Stomach and intestines not cut May have shorter recovery time Band is adjustable (going on a cruise isnot a reason to empty it!!) Surgery is reversible ( usually for

    complications)

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    Lap Band Disadvantages

    Wt loss slower, less and more variable Persistently high rates of reoperation and

    band removal (15 25%) Less Resolution medical problems Easier to cheat

    Requires Maintenance adjustmentsforever (every 6 - 12 months)

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    Who should get a band?

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    Sleeve Gastrectomy

    BPD developed 1976 BPD with DS 1998 LS BPD w/ DS 2000 Some restriction Mostly malabsorbtion Hormonal effect More complications,

    higher risk

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    Sleeve Gastrectomy

    Two stageLS BPD w/DS proposed 2000

    -LS Sleeve first

    -Intestinal bypass afterinitial wt loss

    -FOUND THAT SOMEDID NOT NEED 2NDSURGERY

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    Sleeve Gastrectomy

    2005 2 studies of LS Sleeve as primaryprocedure showing 53% and 83% EWL at1 yr

    2006 first large study (357pts) showing62% EWL 12m and 67% EWL 2 yrs

    To date 36 studies (2,570 pts) showing33 85% EWL at 5 yrs, AVERAGE 60%

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    Sleeve Gastrectomy

    MECHANISM:

    1.Restriction 100 to 150 cc vs 30cc pouch2.Hormonal Effect

    - decreased grehlen 70%

    - decreased hunger 75%

    - significant effect on diabetes3. No dumping, no malabsorbtion

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    COMPLICATIONS

    LAP BAND GASTRIC BYPASS GASTRIC SLEEVE

    Gastric Prolapse (slip) Anastomotic Leak Staple line Leak

    Band Erosion Bowel Obstruction Bleeding

    Esophageal Dialation Pulm Embolism Stricture

    Port Problems Stricture/Marginal Ulcer Conversion to GBP

    Death .1 - .5% Death .2 - .3% Death .2%

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    Bariatric Surgery

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