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CENTRAL DOGMA To supplement the guided notes packet

Central dogma

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Page 1: Central dogma

CENTRAL DOGMATo supplement the guided notes packet

Page 2: Central dogma

The flow of genetic information from DNA to RNA to protein

Initially, the central dogma of biology was simply thought of as

DNA mRNA protein

Page 3: Central dogma

However, that has been expanded…

DNA RNA Protein

transcription translation

Blue words = initial / classic understanding

Environment

Orange words = new understandings

RNA can be autocatalytic (cut it self up)

Reverse transcription

Proteins can ‘force’ other proteins to mimic themselves. Ex: Prion Diseases

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What do all those nitrogenous bases mean?

On the RNA strand, each bracket contains 3 nucleotides.

3 nucleotides are called a codon, each codon represents an amino acid.

There are 64 (43) possible code words which is more than enough to code for the 20 amino acids

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Now it’s your turn..

You should be able to use the notes you took for homework to complete the questions up through the elongation stage of translation.

Remember: There are lots of resources on the blog to help you!