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Cell Structure & Function By Back Sroke @SCI

Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Page 1: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

Cell Structure & Function

By Back Sroke @SCIE

Page 2: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

Nobel Prize & Cell Chemistry Physiology or medicine

2010 Telomeres (DNA)

2009 RNA Viruses & Caner

2008

2007 Stem cell

2006 RNA RNA

2005 Viruses & diseases

2004 Protein

2003 Cell membrane

2002 Programmed cell death

2001 Cell Cycle

2000 Nerve signal

Page 3: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

Organisms are made up of cells

Page 4: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

Cell Theory• All living things are made up of cells.

• Cells are the basic units of all living things.

• All cells come from pre-existing cells through cell division.

Page 5: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

Microscopes

Page 6: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

Definition of Cell

A cell is the smallest unit that is capable of performing life

functions.

Page 7: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

The size

Page 8: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

REVIEW

• List one key point from the cell theory

• What is the definition of a cell?

• What instrument do you use for looking at cells?

Page 9: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

Animal cell anatomy

Page 10: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

“Typical” Animal Cell

Page 11: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

REVIEW• List one main difference between plant

and animal cells

• Do plant and animal cells have organelles?

• What is the function of organelles?

Page 12: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

Plant cell anatomy

Page 13: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

“Typical” Plant Cell

Page 14: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

REVIEW

• What are the main similarities and differences between plant and animal cells?

Page 15: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

Cell PartsOrganelles

Page 16: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

Surrounding the Cell

Page 17: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

Cell Membrane structure

lipid “tail”

phosphate“head”

• Double layers of fat phospholipid bilayer

• Receptor molecule proteins that receive signals

• Carrier proteins Carry ions in and out of the

cell

Page 18: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

Cell Membrane structure

• separates cell from outside

• controls materials in and out of the cell O2, CO2, food, H2O, nutrients, waste

• recognizes signals from other cells allows communication between cells

Page 19: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

Cell Wall

• Most commonly found in plant cells & bacteria

• Supports & protects cells

• Cellulose cell wall

Page 20: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

REVIEW

• Which structure surrounds a cell?

• The functionos of the cell surface membrane?

• The structure of the cell surface membrane?

Page 21: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Cell Membrane ProteinsCell Membrane Proteins

• Proteins help move large molecules or aid in cell recognition

• Peripheral proteins are attached on the surface (inner or outer)

• Integral proteins are embedded completely through the membrane

Page 22: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Recognize “self”

GLYCOPROTEINSGLYCOPROTEINS

Glycoproteins have carbohydrate tails to act as markers for cell recognition

Page 23: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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• Lies immediately against the cell wall in plant cells

• Pushes out against the cell wall to maintain cell shape

Cell Membrane in PlantsCell Membrane in PlantsCell membrane

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Page 24: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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• Nonliving layer• Found in plants,

fungi, & bacteria• Made of cellulose in

plants• Made of

peptidoglycan in bacteria

• Made of chitin in Fungi

Cell wallCell WallCell Wall

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Page 25: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Cell WallCell Wall• Supports and

protects cell• Found outside of

the cell membrane

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Page 26: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

Inside the Cell

Page 27: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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OrganellesOrganelles

• Very small (Microscopic)

• Perform various functions for a cell

• Found in the cytoplasm

• May or may not be membrane-bound

Page 28: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Animal Cell OrganellesAnimal Cell Organelles

Nucleolus

Nucleus

Nuclear envelope

Ribosome (attached)

Ribosome (free)

Cell Membrane

Rough endoplasmic reticulum

Golgi apparatus

Mitochondrion

Smooth endoplasmicreticulum

Centrioles

Page 29: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Plant Cell OrganellesPlant Cell Organelles

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Page 30: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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• Jelly-like substance enclosed by cell membrane

• Provides a medium for chemical reactions to take place

Cytoplasm of a CellCytoplasm of a Cell

cytoplasm

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Page 31: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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• Contains organelles to carry out specific jobs

• Found in ALL cells

More on CytoplasmMore on Cytoplasmcytoplasm

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Page 32: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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• Controls the normal activities of the cell

• Contains the DNA in chromosomes

• Bounded by a nuclear envelope (membrane) with pores

• Usually the largest organelle

The Control Organelle - NucleusThe Control Organelle - Nucleus

Page 33: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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• Each cell has fixed number of chromosomes that carry genes

• Genes control cell characteristics

Nucleus

More on the NucleusMore on the Nucleus

Page 34: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Inside the Nucleus -The genetic material (DNA) is

found

DNA is spread out And appears as

CHROMATINin non-dividing cells

DNA is condensed & wrapped around proteins forming

as CHROMOSOMES in dividing cells

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Page 35: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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MitochondrionMitochondrion(plural = mitochondria)(plural = mitochondria)

• “Powerhouse” of the cell• Generate cellular energy

(ATP)• More active cells like

muscle cells have MORE mitochondria

• Both plants & animal cells have mitochondria

• Site of CELLULAR RESPIRATION (burning glucose)

Page 36: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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MITOCHONDRIA

Surrounded by a DOUBLE membrane

(increases surface areafor more chemical Reactions)

Has its own DNA

Page 37: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Interesting Fact ---Interesting Fact ---

• Mitochondria Come from cytoplasm in the EGG cell during fertilization

Therefore …

• You inherit your

mitochondria from your mother!

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Page 38: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Rod shape

Cell PowerhouseCell Powerhouse

Mitochondrion( mitochondria )

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Page 39: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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What do mitochondria do?What do mitochondria do?

Burns glucose to release energy (ATP)

Stores energy as ATP

“ Power plant” of the cell

Page 40: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Cilia & FlagellaCilia & Flagella

• Cilia are shorter and more numerous on cells

• Flagella are longer and fewer (usually 1-3) on cells

Page 41: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Cell Movement with Cilia & Cell Movement with Cilia & FlagellaFlagella

Page 42: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Cilia Moving Away Dust Particles from Cilia Moving Away Dust Particles from the Lungsthe Lungs

Respiratory SystemRespiratory System

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Page 43: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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VacuolesVacuoles• Fluid filled sacks for storage• Small or absent in animal cells• Plant cells have a large Central Vacuole• No vacuoles in bacterial cells

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Page 44: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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VacuolesVacuoles

• In plants, they store Cell Sap

• Includes storage of sugars, proteins, minerals, lipids, wastes, salts, water, and enzymes

Page 45: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Contractile VacuoleContractile Vacuole• Found in unicellular

protists like paramecia• Regulate water intake

by pumping out excess (homeostasis)

• Keeps the cell from lysing (bursting)

Contractile vacuole animation

Page 46: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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ChloroplastsChloroplasts

• Found only in producers (organisms containing chlorophyll)

• Use energy from sunlight to make own food (glucose)

• Energy from sun stored in the Chemical Bonds of Sugars

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Page 47: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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ChloroplastsChloroplasts• Surrounded by DOUBLE

membrane• Outer membrane smooth• Inner membrane modified

into sacs called Thylakoids• Thylakoids in stacks called

Grana & interconnected• Stroma – gel like material

surrounding thylakoids

Page 48: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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ChloroplastsChloroplasts

• Contains its own DNA

• Contains enzymes & pigments for Photosynthesis

• Never in animal or bacterial cells

• Photosynthesis – food making process

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Page 49: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Cell Size

Question:Are the cells in an elephant bigger, smaller, or about the same size as those in a mouse?

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Page 50: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Cell Size• When the surface area is no longer great

enough to get rid of all the wastes and to get in enough food and water, then the cell must divide

• Therefore, the cells of an organism are close in size

Page 51: Cell Structure & Function By Back Sroke @SCIE Nobel Prize & Cell Chemistry Physiology or medicine 2010 Telomeres (DNA) 2009RNAViruses & Caner 2008 2007

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Cell SizeQuestion:

Are the cells in an elephant bigger, smaller, or about the same size as those in a mouse?

About the same size, but …

The elephant has MANY MORE cells than a mouse!

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