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3/23/2016 1 Welcome to AP Biology Saturday Study Session Cell Division and Heredity Question 1 b Clue: sister chromatids dispersed in the cell and kinetochores attached to the mitotic spindle Mitosis is a continuous process with observable structural features The Cell Cycle Question 2 c Clue: Time after Induction (hours) 0 2 4 6 8 10 12 14 Average Amount of DNA per Cell (fg) 24 40 47.5 48 24 13 12 12

Cell Division and Heredity Presentation and Answersslhsapbiology.weebly.com/uploads/5/8/8/8/58880189/05-ap_bio_cell... · Cell Cycle Most cells exhibit anchorage dependence and density‐

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Page 1: Cell Division and Heredity Presentation and Answersslhsapbiology.weebly.com/uploads/5/8/8/8/58880189/05-ap_bio_cell... · Cell Cycle Most cells exhibit anchorage dependence and density‐

3/23/2016

1

Welcome to AP BiologySaturday Study Session 

Cell Division and Heredity

Question 1

bClue: sister chromatids dispersed in the cell and kinetochores attached to the 

mitotic spindle

Mitosis is a continuous process with observable structural features

The Cell Cycle Question 2

cClue:

Time after Induction (hours) 0 2 4 6 8 10 12 14

Average Amount of DNA per Cell (fg)

24 40 47.5 48 24 13 12 12

Page 2: Cell Division and Heredity Presentation and Answersslhsapbiology.weebly.com/uploads/5/8/8/8/58880189/05-ap_bio_cell... · Cell Cycle Most cells exhibit anchorage dependence and density‐

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Question 3

aClue: non‐sister chromatids exchange 

genetic material

Crossing Over Contributes to Genetic Variation  Independent Assortment Contributes to Genetic Variation

Random Fertilization Contributes to Genetic Variation Question 4

cClue: abnormal number of chromosomes in sex cells

Page 3: Cell Division and Heredity Presentation and Answersslhsapbiology.weebly.com/uploads/5/8/8/8/58880189/05-ap_bio_cell... · Cell Cycle Most cells exhibit anchorage dependence and density‐

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NondisjunctionDown Syndrome

Chromosomal Abnormalities Question 5

dClue: 

Roan = RWRed = RR

White = WW

RW RWRW RW

RR

W      W

Question 6

bClue: 6:2 can be reduced to 3:1

Question 7

dClue: Males are more affected than 

females

Page 4: Cell Division and Heredity Presentation and Answersslhsapbiology.weebly.com/uploads/5/8/8/8/58880189/05-ap_bio_cell... · Cell Cycle Most cells exhibit anchorage dependence and density‐

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Sex‐Linked Recessive Pedigree

• Males are more often affected than females. 

• Affected fathers do not pass to their sons.

Question 8

cClue: Mendelian rules

Question 9

aClue: environment influences gene 

expression

Math Grid In 1

The correct answer: 0.111Solution:• Both Karen and Steve are products of Aa x Aa crosses • Both Karen and Steve are either AA or Aa• Given the genotypic ratio of 1 AA : 2 Aa : 1 aa in a Aa x Aa cross, Karen and Steve each have a 2/3 chance of being carriers

• The overall probability of their child having the disease is 2/3 (the chance of Karen being a carrier) x 2/3 (the chance of Steve being a carrier) x 1/4 (the chance of two carriers having a child with the disease) = 1/9 = 0.111 

Math Grid In 2

The correct answer: 1/32

Solution:AaBbCcDd x AaBBccDd

AaBBCcdd?

A        a B       b C         c D         d

½ Aa         x        ½ BB             x         ½ Cc       x          ¼ dd

AA Aa

Aa aa

Aa

BB Bb

BB Bb

Cc cc

Cc cc

DD Dd

Dd dd

BB

cc

Dd

Short Free Response 14 points possible

1 pt per bullet:• Prediction of a 1:1:1:1 ratio with correct phenotypes based on 

independent assortment• Support for prediction with a diagram of the cross of BbEe x bbee• Correct application of chi‐square analysis to show that observed 

results do not conform to expected Mendelian frequencies• Identification of body color and eye color as linked genes/loci• Use of ratios to show linkage and independent assortment of 

wing type versus linked traits• Identification of the bottom two phenotypes as products of 

crossing over (recombinant chromosome)• Mentioning that crossover rate is approximately 9‐10 percent

Page 5: Cell Division and Heredity Presentation and Answersslhsapbiology.weebly.com/uploads/5/8/8/8/58880189/05-ap_bio_cell... · Cell Cycle Most cells exhibit anchorage dependence and density‐

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Linked Genes

Short Free Response 23 points possible

Regulation: Correct description of checkpoints, which block cell cycle progress unless specific molecular and/or physiological conditions are satisfied – 1 pt each; 2 pts maximum:• Action of MPF and CDKs in checkpoint regulation• Contact inhibition of mitosis• Growth factor control of cell cycle activity

Correct discussion of the consequences of abnormal cell cycle regulation – 1 pt maximum:• Uncontrolled cell proliferation, as in cancer• Apoptosis• Non‐disjunction/aneuploidy/broken chromosomes from 

abnormal spindle events

Checkpoints Regulate the Cell Cycle

Most cells exhibit anchorage dependence and density‐dependent inhibition of cell division

Long Free Response 

Please see the rubric in the separate folder.

Page 6: Cell Division and Heredity Presentation and Answersslhsapbiology.weebly.com/uploads/5/8/8/8/58880189/05-ap_bio_cell... · Cell Cycle Most cells exhibit anchorage dependence and density‐