ySee above: Injurious stimulus or inability to adapt l ead to reversible cell injury. If point of irreversibility is reachednecrosis.Types of Cell Death yApoptosis: oUsually a regulated, controlled processoPlays a role in embryogenesis oA method of controlled cell populationoProgrammed cell deathoNecessary for maturation of cell developmentyNecrosis:oAlways pathologic the result ofirreversible injuryoNumerous causesoThe sum of all morphologicchanges occurring aftercell deathoTypes:Coagulative (most common)LiquefactiveCaseous: combination ofliquefactive and coagulativenecrosisFat necrosisGangrenous necrosis:combination of liquefactive and coagulative necrosisCoagulative Necrosis yCells basic outline is preserved, but not nucleus. yHomogeneous, glassy eosinophlic appearance due to loss of cytoplasmic RNA (basophilic) and glycogen (granular) yNucleus may show pyknosis, karyloysis, or karyorrhexis (definitions from last lecture) Subject: Pathology Topic: Cell Injury and Death 2 & Cell Growth Lecturer: Dr. Luis Cruz Date of Lecture: 06/14/2011 Transcriptionist: CELLOmapas Editor: kChristel PaokPages: 17 S Y 2 0 1 1 2 0 1 2