Sources: Dräger, Unicef, WHO Research Article: A High-Value, Low-Cost Bubble Continuous Positive Airway Pressure System for Low-Resource Settings: Technical Assessment and Initial Case Reports United Nations Inter-agency Group for Child Mortality Estimation (UN IGME), ‘Levels & Trends in Child Mortality: Report 2017, Estimates Developed by the UN Inter-agency Group for Child Mortality Estimation’, United Nations Children’s Fund, New York, 2017. Manufactured by Pluss Advanced Technologies Pvt. Ltd. PDF-8607-2 Child dies before his or her fifth birthday Child dies in the first month Sub-Saharan Africa World’s high-income countries 1:13 1:189 1:36 1:133 CAUSES FOR NEWBORN MORTALITY IN DEVELOPING COUNTRIES The world has made substantial progress in reducing child mortality in the past several decades. Nevertheless, the mortality-rate in developing countries is still very high and the progress in reducing neonatal mortality is slower than in mortality among children aged 1–59 months. Deaths among children aged 1–59 months (54%) Neonatal deaths (46%) 3% Pneumonia 13% Preterm birth complications 16% Intrapartum- related events incl. birth asphyxia 11% Sepsis or meningitis 7% Congenital 5% Pneumonia Other 12% Diarrhoea 8% Injury 6% Malaria 5% Children in sub-Saharan Africa and Southern Asia face a higher risk of dying before their fifth birthday. Under-five mortality rate (deaths per 1,000 live births) by country, 2016 Note: The classification is based on unrounded numbers. This map does not reflect a position by UN IGME agencies on the legal status of any country or territory or the delimitation of any frontiers. Deaths per 1,000 live births >100 75 to 100 50 to 75 25 to 50 ≤25 No data THE PROBLEM Pneumonia, diarrhoea and malaria remain among the leading causes of death among children under age 5. Global distribution of deaths among children under age 5, by cause, 2016 THE CAUSES Helping infants with respiratory distress to breathe easier. Seattle PAP – Bubble CPAP System is a simple and effective non-invasive solution for respiratory support. NON-INVASIVE THERAPY FOR NEONATAL BREATHING SUPPORT Birth asphyxia and Hypoxic-Ischemic Encephalopathy are two of these events. Most under-five deaths are caused by diseases that are readily preventable or treatable with proven, cost-effective interventions. INTRAPARTUM-RELATED EVENTS ARE THE SECOND MAJOR CAUSE OF ALL NEONATAL DEATHS WORLDWIDE² DISPARITIES IN CHILD SURVIVAL EXIST ACROSS REGIONS AND COUNTRIES EFFECTIVE THERAPY FOR ASPHYXIA MiraCradle is an affordable, cooling device to induce therapeutic hypothermia in newborns suffering from birth asphyxia. Nearly half of all deaths in children under age 5 are attributable to undernutrition These two interventions support you to reduce newborn mortality. RDS remains one of the most common causes of the 3 million annual neonatal deaths in the developing world. 20–38% of deaths in the first 48 hours of life are attributed to respiratory failure. The time periods which demonstrated the greatest decline in RDS-specific mortality was linked to the introduction of the Continuous Positive Airway Pressure (CPAP) ventilator. Lack of breathing/Respiratory Distress Syndrome (RDS) Birth asphyxia and Hypoxic-Ischemic Encephalopathy, are the 2nd leading cause of all neonatal deaths worldwide. > 630,998 babies die because of asphyxia globally > 90% of these in underdeveloped countries Five studies have shown that whole-body hypothermia treatment can help to reduce the risk of death or disability.

CAUSES FOR NEWBORN MORTALITY IN DEVELOPING ......RDS remains one of the most common causes of the 3 million annual neonatal deaths in the developing world. 20–38% of deaths in the

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Page 1: CAUSES FOR NEWBORN MORTALITY IN DEVELOPING ......RDS remains one of the most common causes of the 3 million annual neonatal deaths in the developing world. 20–38% of deaths in the

Sources: Dräger, Unicef, WHOResearch Article: A High-Value, Low-Cost Bubble Continuous Positive Airway Pressure System for Low-Resource Settings: Technical Assessment and Initial Case Reports

United Nations Inter-agency Group for Child Mortality Estimation (UN IGME), ‘Levels & Trends in Child Mortality: Report 2017, Estimates Developed by the UN Inter-agency Group for Child Mortality Estimation’, United Nations Children’s Fund, New York, 2017.

Manufactured by Pluss Advanced Technologies Pvt. Ltd.

PDF-86

07-2

Child dies before his or her fif th birthday

Child dies in the first month

Sub-Saharan Africa World’s high-income countries

1:13

1:189

1:36

1:133

CAUSES FOR NEWBORN MORTALITYIN DEVELOPING COUNTRIES

The world has made substantial progress in reducing child mortality in the past several decades. Nevertheless, the mortality-rate in developing countries is still very high and the progress in reducing neonatal mortality is slower than in mortality among children aged 1–59 months.

Deaths among childrenaged 1–59 months (54%)

Neonatal deaths(46%)

Pneumonia 13% Preterm birth

complications

16%

Intrapartum-related eventsincl. birth asphyxia

11%

Sepsis or meningitis

Congenital 5%

Pneumonia

Other 12%

Diarrhoea 8%

Injury 6%

Malaria 5%

Children in sub-Saharan Africa and Southern Asia face a higher risk of dying before their fif th birthday.

Under-five mortality rate(deaths per 1,000 live births)by country, 2016

Note: The classification is based on unrounded numbers. This map does not reflect a position by UN IGMEagencies on the legal status of any country or territory or the delimitation of any frontiers.

Deaths per 1,000 live births

>100

75 to 100

50 to 75

25 to 50

≤25

No data

THE PROBLEM

Pneumonia, diarrhoea and malaria remain among the leading causes of death among children under age 5.

Global distribution of deaths among children under age 5, by cause, 2016

THE CAUSES

Helping infants with respiratorydistress to breathe easier.Seattle PAP – Bubble CPAP System is a simple and effective non-invasive solution for respiratory support.

NON-INVASIVE THERAPY FORNEONATAL BREATHING SUPPORT

Birth asphyxia and Hypoxic-Ischemic Encephalopathyare two of these events. Most under-five deaths are causedby diseases that are readily preventable or treatable withproven, cost-effective interventions.

INTRAPARTUM-RELATED EVENTS ARE THESECOND MAJOR CAUSE OF ALL NEONATALDEATHS WORLDWIDE²

DISPARITIES IN CHILD SURVIVAL EXISTACROSS REGIONS AND COUNTRIES

EFFECTIVE THERAPYFOR ASPHYXIA

MiraCradle is an affordable, coolingdevice to induce therapeutic hypothermia innewborns suffering frombirth asphyxia.

Nearly half of all deaths in children under age 5 are attributable to undernutrition

These two interventions support you to reduce newborn mortality.

RDS remains one of the most common causes of the 3 million annual neonatal deaths in the developing world.

20–38% of deaths in the first 48 hours of life are attributed to respiratory failure.

The time periods which demonstrated the greatest decline in RDS-specific mortality was linked to the introduction of the Continuous Positive Airway Pressure (CPAP) ventilator.

Lack of breathing/Respiratory Distress Syndrome (RDS)

Birth asphyxia and Hypoxic-IschemicEncephalopathy, are the 2nd leading cause ofall neonatal deaths worldwide.

> 630,998 babies die becauseof asphyxia globally

> 90% of these inunderdeveloped countries

Five studies have shown that whole-body hypothermiatreatment can help to reduce the risk of death or disability.