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American Laboratory Products Company
(ALPCO) was founded in 1991 as an importer
and distributor of immunoassay based
products for the North American life science
markets. Our origin began through an exclusive
partnership with a European manufacturer,
Bühlmann Laboratories, located just outside
of Basel Switzerland. Over the past two
decades, ALPCO has become a premier channel
representing over 60 collaborating partners
from around the globe. In late 2008, we
launched our organically developed product
line focused in the area of diabetes and obesity
research, while also remaining true to our
roots by continuing to provide “Immunoassays
Beyond the Ordinary.”
As ALPCO has evolved, we’ve expanded our
offering into applications for HPLC, LC-MS/
MS, purified antibodies, recombinant proteins
and most recently flow cytometry based
reagents. This next year will prove exceptionally
productive as our offering will continue to
grow by over 400 new products, with a specific
development focus in our new STELLUX line
of chemiluminescent based detection systems.
While our vision has expanded to serve a
broader segment of life science research and
healthcare professionals dedicated to improving
patient outcomes, our mission to deliver
“Scientific Solutions for Life” remains the same.
- Sean G. Conley, President
Allergy
Bone Metabolism
CVD & Oxidative Stress
Diabetes & Obesity
Endocrinology
Gastroenterology
Immunology
Neurobiology
Toxicology
Flow Cytometry
Accessories & Equipment
Index
Ordering Information
4
20
26
36
46
56
64
90
98
106
124
126
132
Table of Contents
Website
ALPCO continually strives to provide you with
informative and resourceful content instantly via our
website. The Clinical and Research sections allow you to
download tailored information in your area of interest,
or learn more about featured products and biomarkers
in our “Did You Know?” segments. For more detailed
information on a product you can visit the product pages
for specifications, protocols, or MSDS as well as check
pricing and order online 24/7. You’ll also want to visit for
updates on News, Events, and promotional information.
Resources
Our knowledgeable and responsive technical support
team is here to help you. View the Resources section of
our website for answers to frequently asked questions,
technical tips and interactive tools. You can submit
an inquiry at any time and our dedicated technical
representatives will assist in finding an optimal solution to
your testing needs.
Gastroenterology
4
Allergy & Infectious Disease
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
The immune system protects our body against several factors including allergens,
harmful pathogens and foreign particles. Allergies involve an exaggerated response of
the immune system and are among the most common chronic conditions worldwide.
Infectious disease agents are also one of the leading contributors to debilitating
and sometimes fatal conditions. Therefore, researchers and practitioners look to
understand interactions between microbes and the immune system in order to
translate this knowledge into treatment, control and prevention of conditions caused by
allergies and infectious disease.
Allergy Testing
Identification of allergens causing immediate type
reactions can be a very difficult task for allergists.
The method of investigation usually starts with patient
anamnesis followed by skin and specific IgE tests.
However, results from these tests are often unclear and
inconclusive due to cross reactivity, low sensitivity, or
non-IgE mediated allergies, making a provocation test
necessary, bearing the risk of an anaphylactic event.
5
Allergy & Infectious Disease
FlowCAST® Basophil Activation Assays
ALPCO is the exclusive distributor of BÜHLMANN
Laboratories’ FlowCAST® allergy assays and allergens.
FlowCAST® offers an easy, fast and reliable solution
for allergy determination utilizing basophil activation
measurement via flow cytometry. In vitro basophil
activation testing reduces the risk of an anaphylactic
event and patient discomfort while also providing a
sensitive, quantitative measurement of non-IgE mediated
reactions which serum IgE methods are
unable to achieve.
Upon allergen contact, sensitized basophils degranulate
and express the cell surface marker CD63. In addition,
the surface marker CD203c is upregulated. By labeling
specific antibodies against these surface markers with
fluorochromes, their relative number can be measured
with any four parameter flow cytometer.
Selection of Basophils: Basophils constitutively express
the eotaxin receptor CCR3 allowing for a robust and
accurate selection of cells. CCR3 is measured via a PE-
fluorescence labeled monoclonal antibody. This gating of
basophil cells is significantly easier than with any other
commercially available basophil activation test.
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Adenovirus IgA ELISA 20-AVAHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Adenovirus IgG ELISA 20-AVGHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Adenovirus IgM ELISA 20-AVMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 15m
Anti-Cag-A IgG ELISA 27-GD33Cut-off: See Protocol
6.25 U/mL 10 µL Plasma, Serum 1h 10m
Anti-Candida IgA ELISA 27-GD19 12.5–100 U/mL 0.5 U/mL 5 µL Serum 1h 10m
Anti-Candida IgG ELISA 27-GD22 12.5–100 U/mL 0.5 U/mL 5 µL Serum 1h 10m
Anti-Candida IgM ELISA 27-GD20Cut-off: See Protocol
See Protocol 5 µL Serum 1h 40m
Anti-Casein IgA ELISA 27-GD42Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-Chlamydia IgG ELISA 20-CGGHU-E01 See Protocol See Protocol 10 µL Serum 1h 45m
Anti-Cytomegalovirus IgG ELISA
27-GD84Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum 50m
Gastroenterology
6
Allergy & Infectious Disease
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Activation of Basophils: CD63 and CD203c are
currently the best validated basophil activation
markers directly linked to basophil degranulation.
The FlowCAST® assay detects CD63 via a FITC-
fluorescence labeled monoclonal antibody, while the
FlowCAST® High Sensitivity assay detects both CD63
and CD203c via a tandem dye PE-647 fluorescence
labeled monoclonal antibody.
Stimulation Controls: The FlowCAST® assays provide
two stimulation controls, anti-FcεRI and fMLP. The
first control, anti-FcεRI, is a highly specific monoclonal
antibody binding to IgE receptor. The second control,
a tripeptide fMLP, activates basophils by a non-
immunological method.
Allergens: BÜHLMANN offers a portfolio of over 150
quality controlled and standardized allergens for use with
the basophil activation assays.
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Anti-Cytomegalovirus IgM ELISA
27-GD85Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum 50m
Anti-Gliadin IgA ELISA 27-GD17 6.25–100 U/mL 0.25 U/mL 10 µL Serum 1h 10m
Anti-Gliadin IgA/IgG ELISA 27-GD77 6.25–100 U/mL 0.5 U/mL 10 µL Plasma, Serum 1h 10m
Anti-Gliadin IgG ELISA 27-GD16 6.25–100 U/mL 0.25 U/mL 10 µL Serum 1h 10m
Anti-HAV ELISA 22-E10 10–50 mIU/mL 0.1 IU/mL 10 µL Plasma, Serum 4h
Anti-HAV IgG ELISA 68-4AGE3Cut-off: See Protocol
See Protocol 10 µLCitrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
1h 30m
Anti-HAV IgM ELISA 68-4AME3Cut-off: See Protocol
See Protocol 5 µLCitrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
2h
Anti-HCV ELISA 68-4NAE3Cut-off: See Protocol
See Protocol 100 µL Plasma, Serum 1h 45m
Anti-Helicobacter Pylori IgA ELISA
27-GD08Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
View basophil activation assays 01-FK-CCR and 01-FK-HSBAT on page 10
7
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Anti-Helicobacter Pylori IgG ELISA
27-GD01 6.25–100 U/mL 6.25 U/mL 10 µL Plasma, Serum 1h 10m
Anti-Helicobacter Pylori IgM ELISA
27-GD124Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum 1h 10m
Anti-Helicobacter Pylori Qualitative IgG ELISA
27-GD21Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 50m
Anti-Helicobactor Pylori ELISA
30-6920Cut-off: See Protocol
See Protocol 100 mg Stool 3h
Anti-Herpes-1 IgG ELISA 27-GD86Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum 50m
Anti-Herpes-1/2 IgM ELISA 27-GD88Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum 50m
Anti-Herpes-2 IgG ELISA 27-GD87Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum 50m
Anti-Ovalbumin IgA ELISA 27-GD40Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-Ovalbumin IgG ELISA 27-GD41Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-Ps-Aeruginosa IgA ELISA
27-GD18 6.25–100 U/mL 1.2 U/mL 100 µL Serum 1h 10m
Anti-Ps-Aeruginosa IgG ELISA
27-GD07 6.25–100 U/mL 0.75 U/mL 100 µL Serum 1h 10m
Anti-Rubella IgG ELISA 27-GD82Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum 50m
Anti-Rubella IgM ELISA 27-GD83Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum 50m
Anti-Soya IgA ELISA 27-GD44Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Aspergillus IgG Antibody ELISA
27-GD29 12.5–100 U/mL 0.17 U/mL 100 µL Serum 1h 10m
Bordetella Pertussis IgA ELISA
20-BPAHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 15m
Bordetella Pertussis IgG ELISA
20-BPGHU-E01 * Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Bordetella Pertussis IgM ELISA
20-BPMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Brucella IgG ELISA 20-BRGHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Brucella IgM ELISA 20-BRMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
C. Trachomatis IFA 50-580-01 See Protocol See Protocol 10 µL Serum 1h
Casomorphin ELISA 30-7010 1–120 ng/mL 1 ng/mL 2 mL Urine Overnight
CAST® ELISA (Leukotriene Function)
01-EK-CAST 50–3,200 pg/mL 20 pg/mL 2 mL Whole Blood 2h 30m
Gastroenterology
8
Allergy & Infectious Disease
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
West NileExposure to West Nile Virus (WNV) causes a disease with a number of symptoms including encephalitis. It is a potentially
neuroinvasive agent that causes asymptomatic infection and fever in humans. ALPCO’s FDA registered West Nile Virus IgM
ELISA employs a recombinant WNV antigen and can be used as a rapid serological marker for WNV infection.
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
CAST® ELISA Jumbo (Leukotriene Function)
01-EK-CAST5 50–3,200 pg/mL 20 pg/mL 2 mL Whole Blood 2h 30m
Chlamydia IgA IFA 50-513-01 See Protocol See Protocol 10 µL Serum 1h
Chlamydia IgG IFA 50-511-01 See Protocol See Protocol 10 µL Serum 1h
Chlamydia IgM IFA 50-512-01 See Protocol See Protocol 5 µL Serum 1h
Chlamydia Trachomatis IgA ELISA
20-CTAHU-E01 See Protocol See Protocol 10 µL Serum 1h 45m
Chlamydia Trachomatis IgM ELISA
20-CTMHU-E01 See Protocol See Protocol 10 µL Serum 1h 45m
DAO ELISA 30-8500 0–15.65 U/mL 0.052 U/mL 50 µL Serum 4h 20m
Dengue IgG ELISA 20-DEGHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Dengue IgM ELISA 20-DEMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Dengue NS1 ELISA 65-DENHU-E01 See Protocol See Protocol 50 µL Serum 1h 51m
Echinococcus Granulosus IgG ELISA
20-EGGHU-E01 * Cut-off: See Protocol
See Protocol 10 µL Serum 20m
Epstein Barr Virus Nuclear Antigen IgG ELISA
20-ENGHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Epstein Barr Virus Nuclear Antigen IgM ELISA
20-ENMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Epstein Barr Virus Viral Capsid Antigen IgA ELISA
20-EVAHU-E01Cut-off: See Protocol
See Protocol 10 µL Citrate Plasma, Serum 1h 45m
Epstein Barr Virus Viral Capsid Antigen IgG ELISA
20-EVGHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Epstein Barr Virus Viral Capsid Antigen IgM ELISA
20-EVMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Fasciola Hepatica IgG ELISA 20-FHGHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
View west nile assays 65-WNGHU-E01 and 65-WNMHU-E01 on page 12
9
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
FlowCAST Highsens® High Sensitivity Basophil
Activation Test01-FK-HSBAT ^ See Protocol See Protocol 100 µL Whole Blood 1h
FlowCAST® Basophil Activation Test
01-FK-CCR See Protocol See Protocol 50 µL Whole Blood 30m
Herpes Simplex Virus 1 IgG ELISA
20-HSGHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Herpes Simplex Virus 1 IgM ELISA
20-HSMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Herpes Simplex Virus 1/2 IgG ELISA
20-HG2HU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Herpes Simplex Virus 1/2 IgM ELISA
20-HM2HU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Herpes Simplex Virus 2 IgG ELISA
20-H2GHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Herpes Simplex Virus 2 IgM ELISA
20-H2MHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Histamine ELISA 17-HISHU-E01 0.3–30 ng/mL See Protocol 25 µL Plasma, Urine Overnight
Histamine ELISA 32-5890 0.39–50 nM 0.05 nM 200 µLBiological Fluids, Cell Culture, Plasma, Urine
Overnight
Histamine ELISA (Cell Culture)
17-HISCC-E01 0.5–50 ng/mL 0.2 ng/mL 20 µL Cell Culture, Urine 1h
Histamine ELISA (In Food) 17-HISHU-E01-FOOD See Protocol 0.15 µg/L See Protocol Food 2h
Histamine ELISA (Stool) 17-HISHU-E01-STL 0.5–50 ng/mL 6.1 ng/g See Protocol Stool 2h
Histamine Research ELISA 17-HISRT-E01-RES 0.3–30 ng/mL 0.2 ng/mL 10 µL EDTA Plasma Overnight
Influenza A IgA ELISA 20-IAAHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Influenza A IgG ELISA 20-IAGHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Influenza A IgM ELISA 20-IAMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Influenza B IgA ELISA 20-IBAHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Influenza B IgG ELISA 20-IBGHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Influenza B IgM ELISA 20-IBMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Japanese Encephalitis IgG ELISA
65-JEGHU-E01 See Protocol See Protocol 4 µL Serum 2h 16m
Japanese Encephalitis IgM ELISA
65-JEMHU-E01 See Protocol See Protocol 4 µL Serum 3h 16m
Measles IgM ELISA 20-MEMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Gastroenterology
10
Allergy & Infectious Disease
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Mumps IgG ELISA 20-MUGHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Mumps IgM ELISA 20-MUMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Mycobacterium Tuberculosis IgG ELISA
65-TBGHU-E01 See Protocol See Protocol 4 µL Serum 1h 16m
Mycobacterium Tuberculosis IgM ELISA
65-TBMHU-E01 See Protocol See Protocol 4 µL Serum 1h 16m
Mycoplasma Hominis IgA ELISA
20-MHAHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Mycoplasma Hominis IgG ELISA
20-MHGHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Mycoplasma Hominis IgM ELISA
20-MHMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 2h 25m
Orientia Tsutsugamushi IgG ELISA
65-OTGHU-E01 See Protocol See Protocol 4 µL Serum 1h 16m
Orientia Tsutsugamushi IgM ELISA
65-OTMHU-E01 See Protocol See Protocol 4 µL Serum 1h 16m
Parvovirus B 19 IgG ELISA 20-PBGHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Parvovirus B 19 IgM ELISA 20-PBMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Respiratory Syncytial Virus IgA ELISA
20-RSAHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Respiratory Syncytial Virus IgG ELISA
20-RSVHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 2h
Respiratory Syncytial Virus IgM ELISA
20-RSMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Syphilis IgG ELISA 20-SYGHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Syphilis IgM ELISA 20-SYMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Syphilis Screen ELISA 20-SYSHU-E01Cut-off: See Protocol
See Protocol 20 µL Plasma, Serum 2h 30m
Syphilis Screen IgG/IgM ELISA
20-TPSHU-E01Cut-off: See Protocol
See Protocol 100 µL Plasma, Serum 1h 45m
Tetanus Toxin IgG ELISA 20-TETHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Toxoplasma Gondii IgA ELISA
20-TGAHU-E01Cut-off: See Protocol
See Protocol 20 µL Serum 1h 15m
Toxoplasma Gondii IgM ELISA
20-TGMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
ToxoPlasma IgG Ab ELISA 27-GD80Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum See Protocol
11
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Ureaplasma Urealyticum IgA ELISA
20-UUAHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Ureaplasma Urealyticum IgG ELISA
20-UUGHU-E01Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 2h 20m
Ureaplasma Urealyticum IgM ELISA
20-UUMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Varicella Zoster IgA ELISA 20-VZAHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Varicella Zoster IgG ELISA 20-VZGHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Varicella Zoster IgM ELISA 20-VZMHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h 45m
Visceral Leishmaniasis ELISA 65-VILHU-E01 See Protocol See Protocol 10 µL Serum 1h 16m
West Nile Virus IgG ELISA 65-WNGHU-E01 See Protocol See Protocol 4 µL Serum 2h 15m
West Nile Virus IgM ELISA 65-WNMHU-E01 * See Protocol See Protocol 4 µL Serum 3h 16m
Gastroenterology
12
Allergy & Infectious Disease
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Allergen Category Sub-Category Description Catalog Number
DRUGS Adjuvants Carboxymethylcellulose 05-BAG2-CE466
DRUGS Adjuvants PEG-4000 05-ABG2-CPEG
DRUGS Analgesic Acetaminophen 05-BAG2-C55
DRUGS Analgesic Diclofenac 05-BAG2-C52
DRUGS Analgesic Dipyrone/Metamizole 05-BAG2-C59
DRUGS Analgesic Ibuprofen 05-BAG2-C53
DRUGS Analgesic Indomethacin 05-BAG2-C54
DRUGS Analgesic Lys-Aspirin 05-BAG2-C51
DRUGS Analgesic Mefenamic Acid 05-BAG2-C56
DRUGS Analgesic Naproxen 05-BAG2-CNAP
DRUGS Analgesic Phenylbutazone 05-BAG2-C57
DRUGS Analgesic Propyphenazone 05-BAG2-C58
DRUGS Antibiotic Amoxicillin 05-BAG2-C204
DRUGS Antibiotic Ampicillin 05-BAG2-C203
DRUGS Antibiotic Benzylpenicilloyl + - Acid, MDM 05-BAG2-C12
DRUGS Antibiotic Benzylpenicilloyl -Polylysin, PPL 05-BAG2-C11
DRUGS Antibiotic Cefaclor 05-BAG2-C34
DRUGS Antibiotic Cefamandole 05-BAG2-C31
DRUGS Antibiotic Cefazolin 05-BAG2-C32
DRUGS Antibiotic Cefuroxime 05-BAG2-C33
DRUGS Antibiotic Cephalosporin C 05-BAG2-C3
DRUGS Antibiotic Cetriaxone 05-BAG2-C35
DRUGS Antibiotic Ciprofloxacin 05-BAG2-C81
DRUGS Antibiotic Clarythromycin 05-BAG2-CCLA
DRUGS Antibiotic Clavulanic Acid 05-BAG2-CCLAV
DRUGS Antibiotic Levofloxacin 05-BAG2-C36
DRUGS Antibiotic Penicillin G 05-BAG2-C1
DRUGS Antibiotic Penicillin V 05-BAG2-C2
DRUGS Antibiotic Rifampicin 05-BAG2-CRIF
13
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use All Allergens are Health Canada Licensed
Allergen Category Sub-Category Description Catalog Number
DRUGS Antibiotic Sulfamethoxazole 05-BAG2-C61
DRUGS Antibiotic Tetracycline 05-BAG2-C75
DRUGS Antibiotic Trimethoprim 05-BAG2-C62
DRUGS Antiseptic Chlorhexidine 05-BAG2-CCHX
DRUGS Contrast Media Iobitridol 05-BAG2-CIOBI
DRUGS Contrast Media Iodixanol 05-BAG2-CIODI
DRUGS Contrast Media Iohexol 05-BAG2-CIOHE
DRUGS Contrast Media Iomeprol 05-BAG2-CIOME
DRUGS Contrast Media Iopamidol 05-BAG2-CIOPA
DRUGS Contrast Media Iopromide 05-BAG2-CIOPR
DRUGS Contrast Media Ioxaglate 05-BAG2-CIOXA
DRUGS Contrast Media Ioxitalamate 05-BAG2-CIOXI
DRUGS Local Anesthetic Articaine 05-BAG2-CART
DRUGS Local Anesthetic Bupivacaine 05-BAG2-CBUP
DRUGS Local Anesthetic Lidocaine 05-BAG2-CLID
DRUGS Local Anesthetic Mepivacaine 05-BAG2-CMEP
DRUGS Myorelaxant Atracurium 05-BAG2-CATR
DRUGS Myorelaxant Cisatracurium 05-BAG2-CCAT
DRUGS Myorelaxant Mivacurium 05-BAG2-CMIV
DRUGS Myorelaxant Pancuronium 05-BAG2-CPAN
DRUGS Myorelaxant Propofol 05-BAG2-CPRO
DRUGS Myorelaxant Rocuronium 05-BAG2-CROC
DRUGS Myorelaxant Suxamethonium 05-BAG2-CSUX
DRUGS Myorelaxant Vecuronium 05-BAG2-CVEC
DRUGS Proton Pump Inhibitors Esomeprazole 05-BAG2-CESO
DRUGS Proton Pump Inhibitors Lansoprazole 05-BAG2-CLAN
DRUGS Proton Pump Inhibitors Omeprazole 05-BAG2-COMe
DRUGS Proton Pump Inhibitors Pantoprazole 05-BAG2-CPANT
DRUGS Proton Pump Inhibitors Rabeprazole 05-BAG2-CRAB
Gastroenterology
14
Allergy & Infectious Disease
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use All Allergens are Health Canada Licensed
Allergen Category Sub-Category Description Catalog Number
ENVIRONMENTAL/OCCUPATIONAL Environmental/Occupational Chloramine-T 05-BAG-K85
ENVIRONMENTAL/OCCUPATIONAL Environmental/Occupational Latex 05-BAG-K82
ENVIRONMENTAL/OCCUPATIONAL Environmental/Occupational Phtalic Anhydride/Acid 05-BAG-K79
ENVIRONMENTAL/OCCUPATIONAL Environmental/Occupational α-Amylase 05-BAG-K87
FOOD Egg Egg White 05-BAG-F1
FOOD Egg Egg Yolk 05-BAG-F75
FOOD Fish/Meat Anisakis 05-BAG-P4
FOOD Fish/Meat Beef 05-BAG-F27
FOOD Fish/Meat Codfish 05-BAG-F3
FOOD Fish/Meat Crab 05-BAG-F23
FOOD Fish/Meat Oyster 05-BAG-F290
FOOD Fish/Meat Pork 05-BAG-F26
FOOD Fish/Meat Shrimp 05-BAG-F24
FOOD Fish/Meat Squid 05-BAG-F258
FOOD Fruit/Vegetable Carrot 05-BAG-F31
FOOD Fruit/Vegetable Celery 05-BAG-F85
FOOD Fruit/Vegetable Orange 05-BAG-F33
FOOD Fruit/Vegetable Peach 05-BAG-F95
FOOD Fruit/Vegetable Tomato 05-BAG-F25
FOOD Grain Baker's Yeast 05-BAG-F45
FOOD Grain Barley Flour 05-BAG-F6
FOOD Grain Maize 05-BAG-F8
FOOD Grain Maize Starch 05-BAG-F81
FOOD Grain Oat Flour 05-BAG-F7
FOOD Grain Rice 05-BAG-F9
FOOD Grain Rye Flour 05-BAG-F5
FOOD Grain Wheat 05-BAG-F4
FOOD Milk/Milk Product Casein 05-BAG-F78
FOOD Milk/Milk Product Cow Milk 05-BAG-F2
15
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use All Allergens are Health Canada Licensed
Allergen Category Sub-Category Description Catalog Number
FOOD Milk/Milk Product α-Lactalbumin 05-BAG-F76
FOOD Milk/Milk Product β-Lactoglobulin 05-BAG-F77
FOOD Seed/Bean/Nut Almond 05-BAG-F20
FOOD Seed/Bean/Nut Cashew Nut 05-BAG-F202
FOOD Seed/Bean/Nut Hazelnut 05-BAG-F17
FOOD Seed/Bean/Nut Peanut 05-BAG-F13
FOOD Seed/Bean/Nut Peanut nARA H 1 05-BAG2-ARAH1
FOOD Seed/Bean/Nut Peanut nARA H 2 05-BAG2-ARAH2
FOOD Seed/Bean/Nut Peanut nARA H 6 05-BAG2-ARAH6
FOOD Seed/Bean/Nut Sesame 05-BAG-F10
FOOD Seed/Bean/Nut Soybean 05-BAG-F14
FOOD ADDITIVES Food Additive Amaranth 05-BAG2-CE123
FOOD ADDITIVES Food Additive Brilliant Black BN 05-BAG2-CE151
FOOD ADDITIVES Food Additive Chromotrope B 05-BAG2-CE122
FOOD ADDITIVES Food Additive Erythosine 05-BAG2-CE127
FOOD ADDITIVES Food Additive Glutamate 05-BAG2-CE621
FOOD ADDITIVES Food Additive Indigo Carmine 05-BAG2-CE132
FOOD ADDITIVES Food Additive Methylene Blue 05-BAG2-C105
FOOD ADDITIVES Food Additive New Coccine 05-BAG2-CE124
FOOD ADDITIVES Food Additive Patent Blue V 05-BAG2-CE131
FOOD ADDITIVES Food Additive Potassium-Metabisulfite 05-BAG2-C113
FOOD ADDITIVES Food Additive Quinoline Yellow 05-BAG2-CE104
FOOD ADDITIVES Food Additive Salicylic Acid 05-BAG2-C114
FOOD ADDITIVES Food Additive Sodium-Benzoate 05-BAG2-C111
FOOD ADDITIVES Food Additive Sodium-Nitrite 05-BAG2-C112
FOOD ADDITIVES Food Additive Sorbic Acid 05-BAG2-CE202
FOOD ADDITIVES Food Additive Sunset Yellow FCF 05-BAG2-CE110
FOOD ADDITIVES Food Additive Tartrazine 05-BAG2-C103
INHALANTS Grass Bermuda Grass 05-BAG-G2
Gastroenterology
16
Allergy & Infectious Disease
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use All Allergens are Health Canada Licensed
Allergen Category Sub-Category Description Catalog Number
INHALANTS Grass Cultivated Rye Grass 05-BAG-G12
INHALANTS Grass Orchard Grass 05-BAG-G3
INHALANTS Grass Perennial Rye Grass 05-BAG-G5
INHALANTS Grass Timothy Grass 05-BAG-G6
INHALANTS Mite/Animal/Insect Acarus siro 05-BAG-D70
INHALANTS Mite/Animal/Insect Cat Epithelium 05-BAG-E1
INHALANTS Mite/Animal/Insect D. farinae 05-BAG-D2
INHALANTS Mite/Animal/Insect D. pteronyssinus 05-BAG-D1
INHALANTS Mite/Animal/Insect Dog Epithelium 05-BAG-E2
INHALANTS Mold Alternaria tenuis 05-BAG-M6
INHALANTS Mold Aspergillus fumigatus 05-BAG-M3
INHALANTS Mold Candida albicans 05-BAG-M5
INHALANTS Mold Cladosporium herbarum 05-BAG-M2
INHALANTS Mold Penicillium notatum 05-BAG-M1
INHALANTS Tree Common Birch 05-BAG-T3
INHALANTS Tree Hazel 05-BAG-T4
INHALANTS Tree Oak 05-BAG-T7
INHALANTS Tree Olive 05-BAG-T9
INHALANTS Weed Common Ragweed 05-BAG-W1
INHALANTS Weed Mugwort 05-BAG-W6
INHALANTS Weed Parietaria Officinalis 05-BAG-W19
INHALANTS Weed Ribwort/Plantain 05-BAG-W9
INSECT VENOMSCrossreactive Carbohydrate Determinants
Bromelain 05-BAG-K202
INSECT VENOMSCrossreactive Carbohydrate Determinants
HRP 05-BAG-K225
INSECT VENOMS Insect Venom European Hornet 05-BAG2-I75
INSECT VENOMS Insect Venom Honey Bee Venom 05-BAG2-I1
INSECT VENOMS Insect Venom Honey Bee Venom Check 05-BAG2-I1CHK
INSECT VENOMS Insect Venom Paper Wasp Venom 05-BAG2-I4
17
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use All Allergens are Health Canada Licensed
Allergen Category Sub-Category Description Catalog Number
INSECT VENOMS Insect Venom Yellow Jacket Venom 05-BAG2-I3
INSECT VENOMS Insect Venom Yellow Jacket Venom Check 05-BAG2-I3CHK
RECOMBINANT ALLERGENS Recombinant Allergen FEL D 1 (Cat Major Allergen) 05-BAG2-FELD1
RECOMBINANT ALLERGENS Recombinant Allergen MAL D 1 (Apple Major Allergen) 05-BAG2-MALD1
RECOMBINANT ALLERGENS Recombinant Allergen TRI A 12 (Wheat Profilin) 05-BAG2-TRIA12
RECOMBINANT ALLERGENS Recombinant Allergen ZEA M 12 (Maize Profilin) 05-BAG2-ZEAM12
ALLERGEN MIXES Allergen Mix6 Grass Mix (Orchard, Meadow fescue, Perenial rye, Timothy, Meadow, Velvet grass)
05-BAG-GX1
ALLERGEN MIXES Allergen MixFood Colorants I Mix (Quinoline yellow, Sunset yellow FCF, Chromotrope B, Amaranth, New coccine)
05-BAG-C101
ALLERGEN MIXES Allergen MixFood Colorants II Mix (Erythrosine, Patent blue V, Indigo carmine, Brilliant black BN)
05-BAG-C102
ALLERGEN MIXES Allergen MixFood Mix (Egg white, Egg yolk, Milk, Codfish, Wheat, Peanut, Soybean, Hazelnut, Shrimp)
05-BAG-FX1
ALLERGEN MIXES Allergen Mix
Inhalant Mix (6-grass mix, Cultivated rye grass, Common birch, Hazel, Mugwort, Ribwort/Plantain, Alternaria tenuis, D. pteronissinus, D. farinae, Cat epithelium, Dog epithelium)
05-BAG-IX1
ALLERGEN MIXES Allergen MixNeuromuscular Blockers Mix (Atracurium, Cisatracurium, Mivacurium, Pancurium, Propofol, Rocuronium, Suxamethonium, Vecuronium)
05-BAG2-CNBX
ALLERGEN MIXES Allergen Mix Ragweed Mix (Common and Giant ragweed) 05-BAG-WX1
ALLERGEN MIXES Allergen MixStorage Mite Mix (Acarus Siro, Lepidoglyphus destructor, Tryophagus putrescentia, Glycyphagus domesticus)
05-BAG-DX1
Gastroenterology
18
Allergy & Infectious Disease
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Bone Metabolism
20
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Bone Metabolism
Bone metabolism is a continual, cyclic interplay of bone growth and resorption that is
carefully orchestrated by the dynamic relationship between osteoclasts, osteoblasts
and an array of hormonal and regulatory influences. The relative levels of these
signaling molecules dictate whether healthy, balanced bone metabolism ensues.
Disturbances to this delicate equilibrium, where reabsorption is greater than growth,
can weaken the skeletal architecture and put one at risk for the development of chronic
and debilitating diseases such as osteoporosis.
As we continue to gain a better understanding of the intricacies of bone metabolism and the key regulators involved,
we may also gain further insights into the underlying mechanisms of bone-related diseases such as:
• Osteopetrosis
• Paget’s Disease
• Rheumatoid Arthritis
• Cancer & Bone Metastases
• Immobilization-induced
bone loss
• Chronic Kidney Disease
21
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
1,25 (OH)2 Vitamin D ELISA
30-2112 5.1–200 pg/mL 4.8 pg/mL 500 µL Plasma, Serum Overnight
1,25 (OH)2 Vitamin D Immunotube Extraction Kit
30-KM1100 See Protocol See Protocol 500 µL Plasma, Serum 1h 8m
25-OH Vitamin D ELISA 30-2109 2–300 nmol/L 2 nmol/L 30 µL Serum Overnight
25-OH Vitamin D HPLC 30-3400 4–1,250 nmol/L 4 nmol/L 500 µL Plasma, Serum See Protocol
Anti-TNF α Inhibitor ELISA (Antibody
Against ENBREL®)30-9653
Cut-off: See Protocol
See Protocol 100 µL Serum Overnight
Anti-TNF α Inhibitor ELISA (Antibody Against Humira®)
30-9652Cut-off: See Protocol
See Protocol 100 µL EDTA Plasma, Serum Overnight
Bone Sialoprotein ELISA 30-4222 3.1–50 ng/mL 1 ng/mL 100 µL Serum 3h
Calcitonin ELISA 21-CALHU-E01 * 10–1,000 pg/mL 1 pg/mL 100 µL Serum 4h 30m
Calcitonin Mouse/Rat IRMA 31-CALRT-R100 12–1,800 pg/mL 0.6 pg/mL 200 µLCell Culture, Plasma, Serum
Overnight
Cathepsin K ELISA 04-BI-20432 11–300 pmol/L 1.1 pmol/L 50 µL Cell Culture, Serum Overnight
SclerostinSclerostin, a protein product of the SOST gene, inhibits
osteoblast activity via antagonism of the Wnt signaling
pathway and plays a key role in the regulation of bone
formation. Reports show that sclerostin expression
and/or circulating levels are elevated in osteoporosis,
immobilization-induced bone loss, rheumatoid
arthritis, multiple myeloma and bone metastases,
making it a therapeutic target of great interest for
the fields of bone and cancer research.1,2,3 There are
indications that sclerostin levels are also elevated with
chronic kidney disease, suggesting relevance in the
study of renal insufficiency. 4,5
Mouse Sclerostin ELISA ALPCO has developed a novel mouse sclerostin
immunoassay and confirmed its specificity through
validation via testing in a sclerostin knock out mouse.
This assay is a highly sensitive ELISA utilizing a polyclonal
antibody based sandwich format for detecting low
circulating levels of sclerostin in mouse samples. It
requires a small volume of serum or heparin plasma, which
facilitates time-course sampling and/or the measurement
of multiple biomarkers with one collection.
Bone Metabolism
22
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
CTGF ELISA 20-CTGHU-E01 1–500 ng/mL 3.24 ng/mL 25 µL Serum 3h 45m
DKK-1 ELISA 04-BI-20412 3.125–50 pmol/L 0.38 pmol/L 15 µL Serum Overnight
DPD ELISA (Urine) 55-DE8007 * 3–300 nmol/L 1.1 nmol/L 50 µL Urine 3h
Fetuin-A ELISA 43-FETHU-E01 * 0.5–3.7 ng/mL 5 ng/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h
Fetuin-A Ultrasensitive ELISA
43-FETHUU-E01 * 0.01–1.30 g/L 40 ng/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture
2h 45m
hCOMP ELISA 13-COMP-200 10–80 ng/mL 10 ng/mL 5 µL Serum Overnight
Hydroxy Pyridinium Crosslinks HPLC
Assay (PYD/DPD)30-3201
7.3–2,500 pmol/mL
7.3 pmol/mL 500 µL Urine See Protocol
IL-6 ELISA 45-IL6HU-E01 7.8–500 pg/mL 2 pg/mL 100 µLCell Culture, EDTA Plasma, Serum
3h
IL-6 ELISA 45-IL6HU-E05 7.8–500 pg/mL 2 pg/mL 100 µLCell Culture, EDTA Plasma, Serum
3h
Human Sclerostin ELISA The Human Sclerostin ELISA is a highly referenced kit as
a regulatory marker of bone turnover, requiring only a 20
µL sample of human plasma or serum. The measurement
of circulating sclerostin in conjunction with other
biomarkers of bone turnover is becoming increasingly
common in the study of bone disorders.
1 Rey JP, Ellies DL. Wnt modulators in the biotech pipeline. Developmental
Dynamics. Mar 2010; Vol 239 No 3: 102-114.
2 Gaudio et al. Increased sclerostin serum levels associated with bone
formation and resorption markers in patients with immobilization-induced
bone loss. J Clin Endocrinol Metabolism. May 2010; Vol 95 No 5: 2248-
2253.
3 Colucci S et al. Myeloma cells suppress osteoblasts through sclerostin
secretion. Blood Cancer. Jun 2011; Vol 1 No 6: e27.
4 Drüeke TB & Lafage-Proust. Sclerostin: just one more player in renal bone
disease? Clin J Am Soc Nephrology. Apr 2011; Vol 6, No 4: 700-703.
5 Cejka D et al. Sclerostin and Dickkopf-1 in renal osteodystrophy. Clin J Am
Soc Nephrology. Apr 2011; Vol 6 No 4: 877-882.
23
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
View sclerostin assays 04-BI-20492 on page 24, and 41-SCLMS-E01 on page 25
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
IL-6 Monkey ELISA 61-IL6MK-E01 1.9–120 U/mL 1.3 U/mL 50 µL Cell Culture, Serum 3h 10m
IL-6 Mouse ELISA 61-IL6MS-E0131.3–2,000 pg/mL
6.5 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
3h 30m
IL-6 Rat ELISA 61-IL6RT-E01 31–2,000 pg/mL 12 pg/mL 50 µL Cell Culture, Serum 3h 10m
Intact PTH Bovine ELISA 31-IPTBO-E01 0–10,000 pg/mL 10 pg/mL 50 µLCell Culture, Plasma, Serum
3h 30m
Myostatin ELISA 30-1012 0.27–195 ng/mL 0.27 ng/mL 30 µL Plasma, Serum 5h
Nt-proCNP ELISA 04-BI-20872 2–40 pmol/L 0.55 pmol/L 50 µLCell Culture, Plasma, Serum
4h 30m
Osteocalcin ELISA (1-43/49) 43-OSNHU-E01 0–64 ng/mL 0.31 ng/mL 25 µL Serum 1h 20m
Osteocalcin Intact ELISA 38-OSTHU-E01 2–90 ng/mL 0.4 ng/mL 25 µL Serum 2h 30m
Osteocalcin Mouse ELISA 31-OSTMS-E01 3.2–95 ng/mL 0.4 ng/mL 20 µLCell Culture, Plasma, Serum
3h
Osteocalcin Rat ELISA 31-OSTRT-E01 0.3–35 ng/mL 0.05 ng/mL 20 µLCell Culture, Plasma, Serum
3h
Osteocalcin RIA 72-OSTEO-CT-US 0–300 ng/mL 0.4 ng/mL 50 µLEDTA Plasma, Heparin Plasma, Plasma, Serum
2h
Osteopontin ELISA 41-OPNHU-E01 0.31–20 ng/mL 0.05 ng/mL 10 µL Heparin Plasma, Urine 3h
Osteopontin Mouse ELISA 41-OPNMS-E01 0.03–2.0 ng/mL 0.015 ng/mL 5 µL Plasma 3h
Osteoprotegerin ELISA 04-BI-20403 25–400 pg/mL 1.4 pg/mL 20 µLCitrate Plasma, EDTA Plasma, Heparin Plasma, Serum
5h 30m
Osteoprotegerin Mouse/Rat ELISA
30-1020125–4,000 pg/mL
125 pg/mL 100 µLCell Culture, Plasma, Serum, Urine
Overnight
Procollagen III Peptide RIA 72-OCFK07-PIIIP 0.1–14 U/mL 0.1 U/mL 20 µL Plasma, Serum 5h
PTH Bioactive Intact Rat ELISA
31-BIPRT-E01 25–2,700 pg/mL 3 pg/mL 25 µL Cell Culture, Plasma 3h 30m
PTH High Sensitive ELISA (1-34)
31-IPTHUU-E01 3.2–143 pg/mL 0.3 pg/mL 150 µLCell Culture, EDTA Plasma, Plasma
3h 30m
PTH Intact ELISA (1-84) 21-IPTHU-E01 * 7–700 pg/mL 1.57 pg/mL 25 µL Serum 3h 30m
PTH Intact Mouse ELISA (1-84)
31-PTHMS-E0132–1,045 pg/mL or 336–2,616 pg/mL
4 pg/mL 20 µL Cell Culture, Plasma 3h 30m
PTH Intact Porcine ELISA 31-IPTPO-E01 0–1,000 pg/mL 1 pg/mL 50 µLCell Culture, Plasma, Serum
3h 30m
PTH Intact Rat ELISA (1-84) 31-IPTRT-E01 25–2,700 pg/mL 1.6 pg/mL 25 µLCell Culture, Plasma, Serum
3h 30m
Sclerostin ELISA 04-BI-20492 15–240 pM 2.6 pM 20 µLEDTA Plasma, Heparin Plasma, Serum
Overnight
Bone Metabolism
24
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Sclerostin Mouse ELISA 41-SCLMS-E0137.5–1,200 pg/mL
17.4 pg/mL 15 µL Heparin Plasma, Serum 5h 20m
sRANKL Mouse/Rat ELISA 30-1019125–4,000 pg/mL
125 pg/mL 100 µLCell Culture, Serum, Urine
Overnight
sRANKL Total ELISA 30-1016 0–60 pg/mL 1.5 pg/mL 10 µLCell Culture, Plasma, Serum
Overnight
Vitamin D Binding Protein ELISA
30-2314 2.2–60 ng/mL 1.23 ng/mL 10 µL Plasma, Serum, Urine 2h 20m
Vitamin D Binding Protein Rat ELISA
41-VDBRT-E013.125–100 ng/mL
3.125 ng/mL 5 µL Plasma, Serum 1h 30m
Vitamin D2/D3 HPLC 30-3420 4–1,250 nmol/L 4 nmol/L 500 µL Plasma, Serum See Protocol
Vitamin K1 HPLC 30-2400 See Protocol 0.15 ng/mL 1 mL Plasma, Serum See Protocol
25
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
26
CVD & Oxidative Stress
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Cardiovascular Disease (CVD) encompasses a constellation of diseases related to the
heart and/or circulatory system. Despite efforts to understand and combat heart-
related disease, the first and fourth leading causes of death in the United States
are coronary disease and ischemic stroke, respectively.1 This is striking, considering
extensive campaigns to educate the public on diet and lifestyle factors that are, in
many cases, controllable. Two primary risk factors for CVD include obesity and Type
2 Diabetes, both of which have continued to be on the rise over the past few decades.
It is evident that regardless of the advancements in scientific knowledge of the disease
and the improvements in diagnosis and treatment, more research is necessary to
further our understanding of CVD.
The American Heart Association has dedicated $3.5 billion to the research of CVD and stroke since the late 1940’s,1
and it continues to fund a spectrum of research from community outreach to genomics. These efforts, combined
with federal and philanthropic funding, facilitate the research required for the identification of novel biomarkers and
testing their relevance in basic, preclinical and clinical research.
1 American Heart Association – Research. 2013. <http://my.americanheart.org/professional/Research/Research_UCM_316889_SubHomePage.jsp>
CVD & Oxidative Stress
27
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
11,12-DHET ELISA 60-DH4 See Protocol 10 pg/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture
See Protocol
11,12-DHET ELISA (10 kits) 60-DH104 See Protocol 10 pg/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture
See Protocol
11,12-DHET ELISA (2 kits) 60-DH14 See Protocol 10 pg/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture
See Protocol
11,12-DHET ELISA (5 kits) 60-DH24 See Protocol 10 pg/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture
See Protocol
14,15-DHET ELISA 60-DH1 See Protocol 10 pg/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
See Protocol
14,15-DHET ELISA (10 kits) 60-DH101 See Protocol 10 pg/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture
See Protocol
14,15-DHET ELISA (2 kits) 60-DH11 See Protocol 10 pg/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture
See Protocol
14,15-DHET ELISA (5 kits) 60-DH21 See Protocol 10 pg/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture
See Protocol
20-HETE ELISA 60-20H1 See Protocol 10 pg/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture
See Protocol
20-HETE ELISA (2 kits) 60-20H11 See Protocol 10 pg/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture
See Protocol
20-HETE ELISA (5 kits) 60-20H21 See Protocol 10 pg/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture
See Protocol
Angiotensin Converting EnzymeAngiotensin Converting Enzyme (ACE) catalyzes the conversion of angiotensin I to angiotensin II and inactivates
bradykinin during blood pressure regulation via the renin-angiotensin system. Measurement of ACE levels with ALPCO’s
FDA registered assay has been shown to aid in the diagnosis and monitoring of conditions such as sarcoidosis, diabetic
nephropathy and cardiovascular disease.1
1 Steven A. Atlas, MD. The Renin-Angiotensin Aldosterone System: Pathophysiological Role and Pharmacologic Inhibition. JMCP. Oct 2007; Vol 13 No 8.
View ACE assays 01-KK-ACK and 01-KK-ACF on page 2928
CVD & Oxidative Stress
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
8-isoPGF2a ELISA 60-8ISO1 See Protocol 10 pg/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
See Protocol
8-isoPGF2a ELISA (10 kits) 60-8ISO101 See Protocol 10 pg/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture
Overnight
8-isoPGF2a ELISA (2 kits) 60-8ISO11 See Protocol 10 pg/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture
See Protocol
8-isoPGF2a ELISA (5 kits) 60-8ISO21 See Protocol 10 pg/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture
See Protocol
ACE Kinetic 01-KK-ACK * ^ 3–150 ACE units 5 ACE Units 25 µL Serum 15m
ACE Kinetic 01-KK-ACK2 * ^ 3–150 ACE Units 5 ACE Units 25 µL Serum 15m
ACE Kinetic High Sensitive 01-KK-ACF 1–30 U/L 1 U/L 80 µL Cerebrospinal Fluid See Protocol
ACE Kinetic Jumbo (1200) 01-KK-ACKX * ^ 3–150 ACE units 5 ACE Units 25 µL Serum 15m
AcSDKP ELISA (N-acetyl-Ser-Asp-Lys-Pro)
32-5881 0.19–25 nM 0.19 nM 150 µL Plasma, Serum, Urine Overnight
ACTH ELISA 21-ACTHU-E01 * 5–500 pg/mL 0.46 pg/mL 200 µL Plasma 5h
Adenosine HPLC 30-8000 0.78–6.84 µM 0.78 µM 500 µL Urine 1h 30m
ADMA ELISA 30-7828 0.1–2 µmol/L 0.05 µmol/L 50 µLCitrate Plasma, EDTA Plasma, Plasma, Serum
Overnight
ADMA Mouse/Rat ELISA 30-3001 0.1–3 µmol/L 0.05 µmol/L 100 µL EDTA Plasma, Serum Overnight
ANP (Atrial Natriuretic Peptide)
is released into circulation from
atrial myocytes in response to fiber
contraction and elevated levels can be
predictive of cardiac dysfunction.1,2
BNP (Brain-derived Natriuretic
Peptide) is expressed in the
ventricular myocardium and
released with contraction. Elevated
levels of BNP can be predictive of
heart failure.1,2
ALPCO offers several assays for the
direct measurement of natriuretic
peptides using small sample volumes
which do not require extraction.
1 Hoffmann U et al. Increased plasma levels of NT-proANP and NT-proBNP as markers of cardiac dysfunction in septic patients. Clin Lab. 2005; Vol 51: 373-379.
2 Ellinor PT, et al. Discordant atrial natriuretic peptide and brain natriuretic peptide levels in lone atrial fibrillation. J Am Coll Cardiology. Jan 2005; Vol 45 No 1:
82-86.
View ANP assays 32-5103, 13-BANI 1 and BNP assay 04-BI-20852W on page 30 29
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
ADMA Xpress ELISA 30-7860 0.1 µM–2 µM 0.1 µM 25 µL EDTA Plasma, Serum 3h
Angiotensin II ELISA 32-5880 1–125 pg/mL 1 pg/mL 100 µL Plasma Overnight
Angiotensin II RIA 01-RK-A22 * 2–500 pg/mL 1 pg/mL 1 mL Plasma Overnight
ANP Rat ELISA 32-510315.6–2,000 pg/mL
15.6 pg/mL 50 µLCitrate Plasma, EDTA Plasma
Overnight
ANP RIA 13-BANI 1 7.8–1,000 pg/mL 3.5 pg/mL 500 µL Plasma Overnight
Anti-GBM & ANCA Rapid Screen ELISA
13-GCP-100 * See ProtocolCut-off: See Protocol
25 µL Serum 30m
Antioxidative Capacity ELISA
30-5200 130–393 µmol/L 130 µmol/L 20 µL Plasma, Serum 15m
Antithrombin III Rat ELISA 41-AT3RT-E01 12.5–400 ng/mL 12.5 ng/mL 5 µL Serum 1h 40m
AOPP Colorimetric Assay 30-7811w 6.25–100 µmol/L 1.5 µmol/L 40 µL EDTA Plasma, Plasma 30m
AOPP Colorimetric Assay (Cuvette)
30-7811c 6.25–100 µmol/L 1.1 µmol/L 400 µL EDTA Plasma, Plasma 30m
Apolipoprotein A1 ELISA 41-APOHU-E01 15.6–500 ng/mL 15.6 ng/mL 100 µL Plasma, Serum 1h 40m
BNP Fragment ELISA (Nt-proBNP 8-29)
04-BI-20852W 5–1,000 fmol/mL 5 fmol/mL 35 µLCell Culture, Plasma, Serum
Overnight
Bradykinin ELISA 48-BRAHU-E017.2–5,000 pg/well
7.2 pg/mL 10 µL Plasma, Urine Overnight
ADMA (Asymmetric
Dimethylarginine) is a protein
found in blood plasma where
elevated levels inhibit synthesis
of nitric oxide thus resulting in
vasoconstriction and increased
blood pressure.1,2 The ADMA
Xpress ELISA allows for quantitative
measurement in human samples
with results in less than four hours.
1 Bouras G et al. Asymmetric Dimethylarginine (ADMA): a promising biomarker for cardiovascular
disease? Curr Top Med Chem. 2013; Vol 13 No 2: 180-200.
2 Böger RH et al. Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction:
its role in hypercholesterolemia. Circulation. Nov 1998; Vol 98 No 18:1842-1847.
L-Arginine L-Citrullin + NO
has vasodilatory effects
inhibits monocyte adhesion
inhibits smooth musclecell proliferation
inhibits platelet aggregation
NO=Endogenous anti-arteriosclerotic molecule:
NO-Synthase
ADMAinhibits
View the ADMA Xpress assay 30-7860 on page 3030
CVD & Oxidative Stress
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Carbonylated Protein ELISA 30-7822156.25–2,500 pmol/mL
156.25 pmol/mL
4 µL
Biological Fluids, Bronchial Lavage, Cell Culture, Cerebrospinal Fluid, Plasma
4h
Ceruloplasmin Rat ELISA 41-CERRT-E0118.75–600 ng/mL
18.75 ng/mL 5 µL Serum 2h 10m
CETP ELISA 47-CETHU-E01 0.2–5 µg/mL 0.2 µg/mL 10 µL Plasma, Serum 3h 15m
Creatine Kinase ELISA 25-CKMHU-E01 7.5–200 ng/mL 7.5 ng/mL 20 µL Serum 1h 20m
CRF-HS Mouse/Rat ELISA 48-CRFMS-E01 0.078–2.5 ng/mL 0.078 ng/mL 50 µL Plasma, Tissue Culture 8h 30m
CRP Canine ELISA 41-CRPCA-E012.125–200 ng/mL
5 ng/mL 5 µL Plasma, Serum 25m
CRP ELISA 30-9710s 1.9–150 ng/mL 0.124 ng/mL 10 µLPlasma, Serum, Stool, Urine
2h 15m
CRP Equine ELISA 41-CRPEQ-E01 10–320 ng/mL 10 ng/mL 5 µL Plasma, Serum 1h 15m
CRP Feline ELISA 41-CRPFE-E013.125–200 ng/mL
3.125 ng/mL 5 µL Plasma, Serum 1h 15m
CRP Mouse ELISA 41-CRPMS-E01 0.39–25 ng/mL 0.39 ng/mL 5 µL Plasma, Serum 25m
CRP Rabbit ELISA 41-CRPRB-E01 6.25–200 ng/mL 5 ng/mL 2 µL Plasma, Serum 25m
CRP Rat ELISA 41-CRPRT-E01 6.25–200 ng/mL 5 ng/mL 5 µL Plasma, Serum 25m
DAO REA 30-8220 2.1–80 U/mL 0.2 U/mL 100 µL Plasma, Serum 2h 30m
Endostatin ELISA 04-BI-20742 0–80 nmol/L 0.2 nmol/L 10 µLCitrate Plasma, EDTA Plasma, Heparin Plasma, Serum
4h 30m
Endothelin Big ELISA 04-BI-20082H 0–3 pmol/IL 0.02 pmol/IL 50 µLCitrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
5h 30m
Endothelin ELISA (1-21) 04-BI-20052 0.02–10 fmol/mL 0.02 fmol/mL 50 µLCell Culture, Plasma, Saliva, Serum, Urine
Overnight
Erythropoietin ELISA 21-EPOHU-E01 * 3–500 mIU/mL 0.6 mIU/mL 400 µL Serum 2h 30m
Ferritin ELISA 25-FERHU-E01 * 15–1,000 ng/mL 5 ng/mL 20 µL Serum 1h 5m
Ferritin Mouse ELISA 41-FERMS-E01 12.5–400 ng/mL 12.5 ng/mL 5 µL Serum 1h 20m
Ferritin Rat ELISA 41-FERRT-E01 12.5–400 ng/mL 12.5 ng/mL 5 µL Biological Fluids 1h 20m
Fetuin-A ELISA 43-FETHU-E01 * 0.5–3.7 ng/mL 5 ng/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h
Fetuin-A Ultrasensitive ELISA
43-FETHUU-E01 * 0.01–1.30 g/L 40 ng/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture
2h 45m
Fibrinogen Canine ELISA 41-FIBCA-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 15m
31
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Fibrinogen ELISA 41-FIBHU-E01 12.5–400 ng/mL 12.5 ng/mL 5 µLBiological Fluids, Plasma, Serum
1h 40m
Fibrinogen Mouse ELISA 41-FIBMS-E01 25–800 ng/mL 25 ng/mL 5 µLCitrate Plasma, Plasma, Serum
1h 40m
Fibrinogen Porcine ELISA 41-FIBPO-E01 12.5–400 ng/mL 12.5 ng/mL 5 µL Plasma, Serum 1h 15m
Fibrinogen Rat ELISA 41-FIBRT-E01 25–800 ng/mL 25 ng/mL 5 µLCitrate Plasma, Plasma, Serum
1h 40m
Fibronectin ELISA 61-FIBHU-E01 0.31–20 ng/mL 0.1 ng/mL 50 µLCell Culture, EDTA Plasma, Heparin Plasma, Serum, Urine
3h 10m
Fibronectin Mouse ELISA 41-FNEMS-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 40m
Fibronectin Rat ELISA 41-FNERT-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 40m
Galectin-3 ELISA 61-GALHU-E01 0.39–25 ng/mL 0.12 ng/mL 50 µLCell Culture, EDTA Plasma, Serum
3h 10m
Glutathione HPLC (GSH/GSSG)
30-1800 620–970 µmol/L 6 µmol/L 100 µL EDTA Plasma, Plasma See Protocol
GPx Activity Assay 30-7031 70 mg/mL See Protocol 20 µL Biological Fluids 1h
GST Activity Assay 30-2631 See Protocol See Protocol 100 µL Biological Fluids 1h
GST-pi ELISA 30-7960 9.4–600 ng/mL 9 ng/mL 25 µL Serum, Tissue Culture Overnight
Haptoglobin Bovine ELISA 41-HAPBO-E0115.6–1,000 ng/mL
15.6 ng/mL 5 µL Plasma, Serum 40m
Haptoglobin Canine ELISA 41-HAPCA-E01 7.81–125 ng/mL 5 ng/mL 5 µL Plasma, Serum 40m
Haptoglobin ELISA 41-HAPHU-E013.125–200 ng/mL
3.125 ng/mL 100 µL Plasma, Serum 35m
Haptoglobin Equine ELISA 41-HAPEQ-E0118.75–600 ng/mL
18.75 ng/mL 5 µL Plasma, Serum 1h 15m
Haptoglobin Feline ELISA 41-HAPFE-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 15m
Haptoglobin Mouse ELISA 41-HAPMS-E01 7.81–125 ng/mL 5 ng/mL 5 µL Plasma, Serum 35m
Haptoglobin Porcine ELISA 41-HAPPO-E01 25–400 ng/mL 5 ng/mL 5 µL Plasma, Serum 40m
Haptoglobin Rabbit ELISA 41-HAPRB-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 30m
Haptoglobin Rat ELISA 41-HAPRT-E01 7.81–125 ng/mL 5 ng/mL 5 µL Plasma, Serum 35m
Hemoglobin ELISA 30-7816A 3.3–100 ng/mL 1.8 ng/mL 100 mg Stool 2h 20m
Hemoglobin Equine ELISA 41-HEMEQ-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h
Hemoglobin Mouse ELISA 41-HEMMS-E01 12.5–400 ng/mL 12.5 ng/mL 5 µL Plasma, Serum 1h 40m
Hemoglobin Rat ELISA 48-HEMRT-E01 5–160 ng/mL 5 ng/mL 100 µL Urine 3h
Hemoglobin Rat ELISA 41-HEMRT-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 30m
32
CVD & Oxidative Stress
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Hemopexin ELISA 41-HMPHU-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Serum 1h 10m
Hemopexin Mouse ELISA 41-HMPMS-E01 12.5–400 ng/mL 12.5 ng/mL 5 µL Serum 1h 30m
Hemopexin Rat ELISA 41-HMPRT-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Serum 1h 20m
Hepcidin 25 LC-MS 30-KM4000 See Protocol 1 ng/mL See Protocol Serum See Protocol
Hepcidin ELISA (25 C-Terminal)
20-HCTHU-E01 2–80 ng/mL 2 ng/mL 20 µL Plasma, Serum 1h 50m
Hepcidin Prohormone ELISA
20-HEPHU-E01 10–1,000 ng/mL 4 ng/mL 50 µL Serum, Urine 3h 30m
Homocysteine ELISA 66-HCYHU-E01 2–50 µmol/L 1 µmol/L 25 µL EDTA Plasma, Serum See Protocol
Homocysteine HPLC 30-2801 See Protocol 0.6 mol/L 50 µL Plasma 1h 50m
Krytopyrrole Colorimetric Assay
30-7823100–1,500 ng/mL
100 ng/mL 1 mL Urine 2h
LCAT ELISA 47-LCAHU-E01 0.14–35 µg/mL 0.14 µg/mL 10 µL Plasma, Serum 3h 15m
Lipoprotein (a) ELISA 55-LPAHU-E01 10–70 mg/dL < 5 mg/dL 5 µL Plasma, Serum 2h 30m
LPL ELISA 47-LPLHU-E01 9–500 ng/mL 9 ng/mL 50 µL Plasma, Serum 4h 15m
Malondialdehyde HPLC 30-1900 See Protocol 0.15 nmol/L 20 µL Plasma, Serum, Urine 1h
MPO ELISA 30-6630 1.2–100 ng/mL 1.6 ng/mL 100 mg Stool, Urine 2h 20m
MPO ELISA (Serum and Plasma)
30-6631A 1.9–30 ng/mL 1.08 ng/mL 10 µL Plasma, Serum 3h 20m
MPO Mouse ELISA 41-MPOMS-E01 0.31–20 ng/mL 0.31 ng/mL 5 µL Plasma, Serum 1h 30m
MRP 8/14 ELISA 01-EK-MRP8/14 0.4–24 µg/mL 0.4 µg/mL 10 µL Plasma, Serum 1h 15m
Myoglobin ELISA 25-MYOHU-E01 * 25–1,000 ng/mL 25 ng/mL 20 µL Serum 1h 5m
Myoglobin ELISA 24-MYOHU-E01 0–250 ng/mL 6.25 ng/mL 10 µL Serum, Urine 30m
Myoglobin Mouse ELISA 41-MYOMS-E01 4.69–300 ng/mL 4.69 ng/mL 30 µL Plasma, Serum 1h 40m
Myoglobin Rat ELISA 41-MYORT-E013.125–200 ng/mL
3.125 ng/mL 75 µL Serum 1h 25m
Nitrotyrosine ELISA 30-7824 32–1,250 nM 34.1 nM 100 mg Plasma, Serum, Stool 4h
NOS1 ELISA 48-NOSHU-E01 0.133–32.4 nM 0.133 nM 50 µL Tissue Culture Overnight
Nt-proCNP ELISA 04-BI-20872 2–40 pmol/L 0.55 pmol/L 50 µLCell Culture, Plasma, Serum
4h 30m
Osteoprotegerin ELISA 04-BI-20403 25–400 pg/mL 1.4 pg/mL 20 µLCitrate Plasma, EDTA Plasma, Heparin Plasma, Serum
5h 30m
Osteoprotegerin Mouse/Rat ELISA
30-1020125–4,000 pg/mL
125 pg/mL 100 µLCell Culture, Plasma, Serum, Urine
Overnight
33
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Oxidized LDL Antibody ELISA
04-BI-20032 37–1,200 mU/mL 27 mU/mL 50 µL Serum 2h 20m
Oxidized LDL ELISA 30-7810 9–250 ng/mL 9 ng/mL 10 µLEDTA Plasma, Plasma, Serum
2h 20m
OxyStat ELISA 04-BI-5007Cut-off: See Protocol
7 µmol/L 10 µL Plasma, Serum 15m
Phospholipase 2 RIA 48-PLAHU-R50100–10,000 ng/dL
100 ng/dL 50 µL Plasma, Serum 2h 30m
Plasminogen Canine ELISA 41-PLACA-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 45m
Plasminogen ELISA 41-PLAHU-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Serum 2h 5m
Plasminogen Mouse ELISA 41-PLAMS-E016.25–1,900 ng/mL
6.25 ng/mL 5 µL Serum 1h 30m
Plasminogen Porcine ELISA 41-PLAPO-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 15m
Plasminogen Rabbit ELISA 41-PLARB-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 30m
Plasminogen Rat ELISA 41-PLART-E013.125–200 ng/mL
3.125 ng/mL 5 µL Plasma, Serum 1h 30m
proANP ELISA (1-98) 04-BI-20892 0.63–10 nmol/L 0.05 nmol/L 10 µLCell Culture, Plasma, Urine
4h
Renin Active RIA 72-RENINE * 0–320 pg/mL 1 pg/mL 300 mL Plasma 3h
Renin Activity ELISA 11-RENHU-E02 0.2–60 ng/mL 0.038 ng/mL 50 µL EDTA Plasma, Plasma 1h 45m
ReninRenin is a constituent of the Renin-Angiotensin-Aldosterone System (RASS) which controls blood pressure, renal blood
flux, glomerular filtration, and sodium/potassium homeostasis.1,2 Plasma renin is a reliable index for the activity of the
RAAS. In cases of dysfunction, renin testing with ALPCO’s FDA registered Active Renin RIA can aid in detection of
renin producing tumors, monitoring of glucocorticoid therapy and antihypertensive treatments and contribute to the
diagnosis of hypertension, hyperaldosteronism, and mineral corticoid deficiency.
1 Basso N, Terragno NA. History about the discovery of the renin-angiotensin system. Hypertension. Dec 2001. Vol 38 No 6: 1246–1249.
2 Chappell MC. Nonclassical Renin-Angiotensin system and renal function. Compr Physiology. Oct 2012; Vol 2 No 4: 2733-2752.
View renin assays 11-RENHU-E02 on page 34, and 20-RENHU-E01 and 11-RENHU-L02 on page 3534
CVD & Oxidative Stress
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Renin Activity LIA 11-RENHU-L02 0.2–25 ng/mL 0.08 ng/mL 500 µL EDTA Plasma, Plasma 1h 30m
Renin ELISA 20-RENHU-E01 0.81–28 pg/mL 0.81 pg/mL 50 µL EDTA Plasma 3h 15m
Serum Amyloid A ELISA 41-SAAHU-E01 0.157–10 ng/mL 0.157 ng/mL 10 µL Plasma, Serum 1h
Serum Amyloid A Mouse ELISA
41-SAAMS-E0131.25–2,000 ng/mL
31.25 ng/mL 5 µL Serum 1h 40m
t-PA ELISA 61-TPAHU-E0115.6–1,000 pg/mL
6 pg/mL 10 µL Cell Culture, Serum 2h 10m
Transferrin Canine ELISA 41-TRACA-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 15m
Transferrin ELISA 41-TRAHU-E019.375–600 ng/mL
9.375 ng/mL 5 µL Plasma, Serum 1h 15m
Transferrin Mouse ELISA 41-TRAMS-E01 1.56–100 ng/mL 1.56 ng/mL 5 µL Plasma, Serum 1h 10m
Transferrin Rabbit ELISA 41-TRARB-E013.125–100 ng/mL
3.125 ng/mL 5 µL Plasma, Serum 1h 30m
Transferrin Rat ELISA 41-TRART-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Biological Fluids 40m
Troponin I ELISA 25-TR1HU-E01 * 1.5–75 ng/mL 1 ng/mL 100 µL Serum 1h 50m
Ubiquinone Coenzyme Q10 HPLC Kit
30-KC-1700 See Protocol 0.02 µg/mL 200 µLPlasma, Serum, Whole Blood
15m
Urotensin II ELISA 30-101332–20,000 pg/mL
32 pg/mL 150 µLCell Culture, Plasma, Serum
4h 10m
Vasopressin Direct RIA (ADH/AVP)
01-RK-VPD ^ 1.25–80 pg/mL 0.75 pg/mL 1 mL EDTA Plasma Overnight
Vasopressin Ultrasensitive RIA (ADH/AVP)
01-RK-AR1 0.63–80 pg/mL 0.4 pg/mL 1 mL EDTA Plasma, Urine Overnight
Vitamin A and Vitamin E HPLC Assay (Retinol and Tocopherol HPLC Assay)
30-1600 See Protocol 0.05 mg/mL 100 µL EDTA Plasma, Serum See Protocol
Vitamin B6 Enzymatic Assay
01-KK-VB6 9–250 nM 7 nM 25 µL EDTA Plasma 45m
Vitamin B6 HPLC 30-2100 4.3–17.9 ng/mL 0.2 ng/mL 200 µLEDTA Plasma, Plasma, Serum
See Protocol
35
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Diabetes & Obesity
36
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
According to the 2011 National Diabetes Fact Sheet, diabetes affects 8.3% of the
U.S. population. It is the leading cause of kidney failure, nontraumatic lower-limb
amputations and new cases of blindness among adults and is a major cause of heart
disease and stroke.1 Globally, diabetes affects 347 million people, with Type 2 diabetes
accounting for approximately 90% of all diagnosed cases2 and is projected to be the
7th leading cause of death in 2030.3 Additionally, obesity is a major risk factor for Type
2 diabetes, and having excess visceral, or abdominal, fat is associated with more than a
twofold-increased risk of developing diabetes.4
With no cure for Type 1 or Type 2 diabetes, and a lack
of effective obesity treatments, investigators are
continually in need of new methods to advance their
research. ALPCO has been a leader in offering solutions
1 Centers for Disease Control and Prevention. National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the
United States, 2011. Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 2011.
2 World Health Organization. Diabetes Fact sheet N°312. Geneva, World Health Organization, 2013.
3 Global status report on noncommunicable diseases 2010. Geneva, World Health Organization, 2011.
4 de Lemos JA, et al. Dysfunctional adiposity and the risk of prediabetes and type 2 diabetes in obese adults. JAMA. Sep 2012; Vol 308 No 11: 1150-1159.
to researchers in the Diabetes & Obesity field and will
continue to support their efforts in gaining a greater
understanding of these conditions.
Diabetes & Obesity
37
Energy Homeostasis
Energy homeostasis is a well-regulated process
that depends on the coordination between feeding
behavior and energy expenditure. The control of energy
homeostasis in humans has received much attention in
recent years due to alterations caused by the onset of
conditions such as obesity and diabetes.
ALPCO offers numerous Research Use Only and
IVD assay kits to assist both academic and industry
researchers with quantification of analytes associated
with energy homeostasis. It is now recognized that there
are many central and peripheral factors involved in
energy homeostasis; understanding of these mechanisms
should lead to effective treatments for the control of
diabetes, obesity and other metabolic disorders.
STELLUX™ Chemiluminescence
Our commitment to support innovation in the Diabetes
and Obesity field has allowed us numerous opportunities
to respond to the changing demands in the market.
ALPCO’s STELLUX™ chemiluminescent detection system
is a result of that commitment.
STELLUX™ is a glow-based chemiluminescent
reaction that delivers rapid and sensitive detection of
analytes, broad dynamic ranges and shorter run times
compared to colorimetric ELISA systems. STELLUX™
chemiluminescence immunoassays will prove to set new
standards in the field of diabetes and obesity research.
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
AAI RIA 72-AAI See Protocol See Protocol 50 µL Plasma, Serum 2h 30m
Acylated Ghrelin ELISA 32-5106 1.95–250 pg/mL 0.8 pg/mL 100 µL Plasma 3h
Adiponectin HMW & Total ELISA
47-ADPHU-E01 0.075–4.8 ng/mL 0.019 ng/mL 10 µLCitrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
3h
Adiponectin HMW & Total Mouse ELISA
47-ADPMS-E01 0.125–8 ng/mL 0.032 ng/mL 5 µLEDTA Plasma, Plasma, Serum
3h
Adiponectin Rat ELISA 22-ADPRT-E01 0.25–10 ng/mL 0.08 ng/mL 5 µL Plasma, Serum 2h 30m
Adiponectin Total ELISA 47-ADPHUT-E01 0.075–4.8 ng/mL 0.019 ng/mL 10 µLEDTA Plasma, Heparin Plasma, Serum
2h 40m
AFABP ELISA 32-5181 0.5–25 ng/mL 0.1 ng/mL 20 µLCell Culture, Plasma, Serum
2h 30m
Diabetes & Obesity
38
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Albumin Canine ELISA 41-ALBCA-E01 12.5–400 ng/mL 12.5 ng/mL 5 µL Plasma, Serum 1h 45m
Albumin ELISA 30-6330 12.5–800 µg/L 12.5 µg/L 100 mg, 10 µL Stool, Urine 2h 20m
Albumin Monkey ELISA 41-ALBMK-E01 12.5–400 ng/mL 12.5 ng/mL 100 µL Serum, Tissue Culture 1h 40m
Albumin Mouse ELISA 41-ALBMS-E01 7.8–500 ng/mL 5 ng/mL 2 µL Plasma, Serum, Urine 1h 10m
Albumin Porcine ELISA 41-ALBPO-E01 12.5–400 ng/mL 12.5 ng/mL 5 µL Plasma, Serum, Urine 1h 40m
Albumin Rat ELISA 41-ALBRT-E01 6.25–400 ng/mL 5 ng/mL 5 µL Plasma, Serum, Urine 1h 10m
Anti-Insulin IgG ELISA 35-INAHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
CCK RIA 13-CCKHU-R100 0.78–25 pmol/L 0.3 pmol/L 1 mL Plasma Overnight
C-Peptide ELISA 80-CPTHU-E01.1 * 20–3,000 pmol/L 2.95 pmol/L 25 µL Plasma, Serum 2h
C-Peptide ELISA Jumbo 80-CPTHU-E10 * 20–3,000 pmol/L 2.95 pmol/L 25 µL Plasma, Serum 2h
C-peptide ELISA Mouse Jumbo
80-CPTMS-E10 60–3,000 pM 7.6 pM 10 µL Serum 2h 15m
C-Peptide IRMA 72-C-Peptide See Protocol 0.036 ng/mL 50 µL Plasma, Serum, Urine 2h
C-peptide Mouse ELISA 80-CPTMS-E01 60–3,000 pM 7.6 pM 10 µL Serum 2h 15m
C-peptide Rat ELISA 80-CPTRT-E01 50–4,500 pM 10.8 pM 10 µL Serum 2h 15m
FGF-21 ELISA 62-FGFHU-E01 30–1,920 pg/mL 10.4 pg/mL 100 µLCell Culture, Plasma, Serum
2h 35m
FGF-21 Mouse ELISA 62-FGFMS-E0131.2–2,000 pg/mL
10.1 pg/mL 100 µLCell Culture, Plasma, Serum
2h 35m
GAD ELISA 21-GADHU-E01 0.6–2.99 U/mL See Protocol 10 µL Serum 2h 30m
Gastrin RIA 13-MD 302 * 15.6–500 pmol/L 5 pmol/L 100 µL Serum 1h 45m
Gastrin RIA 72-GASK-PR 0–500 µU/mL 10 µU/mL 100 µL Plasma, Serum 3h
Ghrelin Acylated Mouse/Rat ELISA
32-5117 1.95–250 pg/mL 0.7 pg/mL 100 µL Plasma 3h
Ghrelin Non-Acylated ELISA
32-5119 1.95–250 pg/mL 0.6 pg/mL 10 µL EDTA Plasma 3h
Ghrelin Non-Acylated Mouse/Rat ELISA
32-5118 1.95–250 pg/mL 0.8 pg/mL 10 µL EDTA Plasma 3h
Ghrelin Total RIA 22-GHR-R90200–6,400 pg/mL
40 pg/mL 100 µL Plasma, Serum Overnight
Glicentin Rat ELISA 48-GLIRT-E010.206–50 pmol/mL
0.206 pmol/mL 30 µL Plasma Overnight
GLP-1 Active ELISA (7-36) 43-GP1HU-E01 0.64–48 pmol/L 0.05 pmol/L 100 µL EDTA Plasma, Plasma Overnight
GLP-1 Total ELISA (7-36 and 9-36)
43-GPTHU-E01 1.8–54.5 pmol/L 0.6 pmol/L 100 µL EDTA Plasma, Plasma Overnight
39
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
GLP-2 ELISA 48-GP2HU-E01.10.412–100 ng/mL
0.412 ng/mL 25 µL Plasma, Serum Overnight
GLP-2 Mouse ELISA 48-GP2MS-E010.412–100 ng/mL
0.412 ng/mL 25 µL Plasma, Serum Overnight
GLP-2 Rat ELISA 48-GP2RT-E01 0.137–100 ng/mL 0.137 ng/mL 25 µL Plasma, Serum Overnight
Glucagon ELISA 48-GLUHU-E0150–10,000 pg/mL
50 pg/mL 50 µL Plasma Overnight
Glucagon RIA 13-GLUHU-R100 * 4.7–150 pmol/L 3 pmol/L 200 µL Plasma Overnight
Glutathione HPLC (GSH/GSSG)
30-1800 620–970 µmol/L 6 µmol/L 100 µL EDTA Plasma, Plasma See Protocol
IL-1ß Rat ELISA 61-I1BRT-E0131.3–2,000 pg/mL
4 pg/mL 50 µL Cell Culture, Serum 3h 10m
IL-6 ELISA 45-IL6HU-E01 7.8–500 pg/mL 2 pg/mL 100 µLCell Culture, EDTA Plasma, Serum
3h
IL-6 ELISA 45-IL6HU-E05 7.8–500 pg/mL 2 pg/mL 100 µLCell Culture, EDTA Plasma, Serum
3h
IL-6 Monkey ELISA 61-IL6MK-E01 1.9–120 U/mL 1.3 U/mL 50 µL Cell Culture, Serum 3h 10m
IL-6 Mouse ELISA 61-IL6MS-E0131.3–2,000 pg/mL
6.5 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
3h 30m
IL-6 Rat ELISA 61-IL6RT-E01 31–2,000 pg/mL 12 pg/mL 50 µL Cell Culture, Serum 3h 10m
IL-8 ELISA 61-IL8HU-E0115.6–1,000 pg/mL
2 pg/mL 50 µLCell Culture, EDTA Plasma, Heparin Plasma, Serum
3h 10m
IL-8 Monkey ELISA 61-IL8MK-E01 19.5–1,250 U/mL 3 U/mL 50 µL Cell Culture, Serum 3h 10m
IL-8 Porcine ELISA 45-IL8PO-E0131.2–2,000 pg/mL
10 pg/mL 50 µL Cell Culture, Serum 4h
IL-8 Ultrasensitive ELISA 45-IL8HUU-E01 0.39–25 pg/mL 0.1 pg/mL 100 µLCell Culture, Plasma, Serum, Urine
4h
Insulin Autoantibody ELISA 21-IAAHU-E01Cut-off: See Protocol
See Protocol 25 µL Serum Overnight
Insulin Bovine ELISA 80-INSBO-E01 0.15–6 ng/mL 0.10 ng/mL 25 µL Plasma, Serum 2h 15m
Insulin ELISA 80-INSHU-E01.1 * 3–200 µIU/mL 0.399 µIU/mL 25 µL Plasma, Serum 2h
Insulin ELISA Jumbo 80-INSHU-E10.1 * 3–200 µIU/mL 0.399 µIU/mL 25 µL Plasma, Serum 2h
Insulin High Range Mouse ELISA
80-INSMSH-E01 3–150 ng/mL 1.99 ng/mL 5 µL Plasma, Serum 2h 15m
Insulin High Range Mouse ELISA Jumbo
80-INSMSH-E10 3–150 ng/mL 1.99 ng/mL 5 µL Plasma, Serum 2h 15m
Insulin High Range Rat ELISA
80-INSRTH-E01 3–150 ng/mL 0.52 ng/mL 5 µL Plasma, Serum 2h
Diabetes & Obesity
40
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Insulin High Range Rat ELISA Jumbo
80-INSRTH-E10 3–150 ng/mL 0.52 ng/mL 5 µL Plasma, Serum 2h
Insulin Mouse ELISA 80-INSMS-E01 0.188–6.9 ng/mL 0.121 ng/mL 10 µL Plasma, Serum 2h
Insulin Mouse ELISA Jumbo 80-INSMS-E10 0.188–6.9 ng/mL 0.121 ng/mL 10 µL Plasma, Serum 2h
Insulin Ovine ELISA 80-INSOV-E01 0.15–4 ng/mL 0.14 ng/mL 25 µL EDTA Plasma, Serum 2h 15m
Insulin Porcine/Canine ELISA
80-INSPO-E01 0.05–2 ng/mL 0.007 ng/mL 25 µL EDTA Plasma, Serum 2h 15m
Insulin Rat ELISA 80-INSRT-E01 0.15–5.5 ng/mL 0.124 ng/mL 10 µL Plasma, Serum 2h
Insulin Rat ELISA Jumbo 80-INSRT-E10 0.15–5.5 ng/mL 0.124 ng/mL 10 µL Plasma, Serum 2h
Insulin STELLUX™ Rodent ELISA
80-INSMR-CH01 0.1–150 ng/mL 0.096 ng/mL 5 µL Plasma, Serum 2h
Insulin Ultrasensitive ELISA 80-INSHUU-E01.1 * 0.15–20 µIU/mL 0.135 µIU/mL 25 µL Plasma, Serum 1h 30m
Insulin Ultrasensitive Mouse ELISA
80-INSMSU-E01 0.025–6.9 ng/mL0.115 ng/mL (5 µL), 0.019 ng/mL (25 µL)
5 µL, 25 µL Plasma, Serum 2h 30m
Insulin Ultrasensitive Mouse ELISA Jumbo
80-INSMSU-E10 0.025–6.9 ng/mL0.115 ng/mL (5 µL), 0.019 ng/mL (25 µL)
5 µL, 25 µL Plasma, Serum 2h 30m
Insulin Ultrasensitive Rat ELISA
80-INSRTU-E010.15–5.5 ng/mL or 0.02–1 ng/mL
0.107 ng/mL (5 µL), 0.002 ng/mL (25 µL)
5 µL, 25 µL Plasma, Serum 2h 30m
GlucagonGlucagon is the counter-regulatory hormone to insulin
and is secreted from pancreatic alpha-cells in response
to low blood glucose. Hyperglucagonemia has been
implicated in the pathophysiology of Type 2 Diabetes
Mellitus. Incretin-based treatments (GLP-1 receptor
agonists, DPP-4 inhibitors) have been shown to suppress
glucagon secretion from the alpha-cells, attributing to the
glucose-lowering effect of these treatments.1 As such, the
inhibition of glucagon may prove to be a viable target for
new drug therapies.
1 Morten Hansen, Kristine J. Hare, Jens J. Holst and Filip K. Knop. Inhibition of Glucagon Secretion by GLP-1 Agonists and DPP4 Inhibitors JCMD. Jun 2011; Vol 2
No 1: 7-13.
View glucagon assays 48-GLUHU-E01 and 13-GLUHU-R100 on page 40
41
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Insulin Ultrasensitive Rat ELISA Jumbo
80-INSRTU-E100.02–1 ng/mL or 0.15–5.5 ng/mL
0.01 ng/mL (5 µL), 0.07 ng/mL (25 µL)
5 µL, 25 µL Plasma, Serum 2h 30m
Islet Cell Antibody ELISA 21-ICAHU-E01Cut-off: See Protocol
See Protocol 25 µL Serum 2h 30m
Leptin ELISA 11-LEPHU-E01 1–100 ng/mL 0.42 ng/mL 20 µL Serum 1h 45m
Leptin Mouse/Rat ELISA 22-LEPMS-E01 15–1,600 pg/mL 10 pg/mL 5 µL Serum 3h
Leptin RIA (Coated Tube) 22-LEP-R44 1–64 ng/mL 0.1 ng/mL 25 µLCell Culture, Plasma, Serum
Overnight
Leptin Ultrasensitive ELISA 22-LEP-E077 0.05–5 ng/mL 0.01 ng/mL 10 µLBiological Fluids, Plasma, Serum
1h 45m
Leptin Ultrasensitive RIA 22-LEP-R40 0.25–16 ng/mL 0.04 ng/mL 33 µLCell Culture, Cerebrospinal Fluid, Plasma, Serum, Urine
Overnight
MCP-1 ELISA 61-MCPHU-E0115.6–1,000 pg/mL
2.3 pg/mL 20 µLCell Culture, EDTA Plasma, Heparin Plasma, Serum
2h 10m
MCP-1 Mouse ELISA 61-MCPMS-E0115.6–1,000 pg/mL
2.2 pg/mL 50 µL Cell Culture, Serum 3h 10m
MCP-1 Rat ELISA 45-MCPRT-E01 11.7–750 pg/mL 8 pg/mL 50 µLCell Culture, Plasma, Serum
2h 30m
Microalbumin ELISA 24-MABHU-E01 0.5–100 µg/mL 0.24 µg/mL 10 µL Urine 40m
AdiponectinAdiponectin circulates as multiple isoforms and is widely
recognized as a key protein involved in insulin regulation
and metabolic syndrome. Measurement of high molecular
weight (HMW) levels, or the ratio of HMW to total
adiponectin, has been shown to aid in predicting insulin
resistance and the development of metabolic syndrome.1
Our HMW & Total Adiponectin ELISAs were developed
for the selective quantification of human or mouse
adiponectin oligomers using a patented protease
pretreatment. These ELISAs directly measure both HMW
and total adiponectin, respectively.
1 Swarbrick MM, Austrheim‐Smith IT, Stanhope KL, et al. Circulating concentrations of high‐molecular‐weight adiponectin are increased following Roux‐en‐Y
gastric bypass surgery. Diabetologia. Nov 2006; Vol 49 No 11: 2552‐2558.
View adiponectin assays 47-ADPHU-E01, 47-ADPMS-E01, 22-ADPRT-E01, and 47-ADPHUT-E01 on page 38
Diabetes & Obesity
42
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Myostatin ELISA 30-1012 0.27–195 ng/mL 0.27 ng/mL 30 µL Plasma, Serum 5h
NGAL Canine ELISA 54-043 4–400 pg/mL 0.56 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Canine ELISA 54-043 4–400 pg/mL 0.56 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL ELISA 54-036 10–1,000 pg/mL 4 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Mouse ELISA 54-042 10–500 pg/mL 0.75 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Porcine ELISA 54-044 10–400 pg/mL 1 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Rapid ELISA 54-037 0.2–20 ng/mL 0.008 ng/mL 10 µLEDTA Plasma, Plasma, Serum, Urine
1h
NPY RIA 13-NPYHU-R100 9.4–300 pmol/L 6 pmol/L 200 µL Plasma, Serum 48h
Obestatin ELISA 48-OBEHU-E01 0.231–25 ng/mL 0.231 ng/mL 20 µL Plasma, Serum Overnight
Obestatin Mouse/Rat ELISA 48-OBEMS-E01 0.082–20 ng/mL 0.082 ng/mL 25 µL Serum Overnight
PAI-1 ELISA 61-PAIHU-E01 78–5,000 pg/mL 29 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
Pancreatic Amylase ELISA 30-6410440–28,000 mU/L
440 mU/L 100 mg Stool 2h 15m
Pancreatic Polypeptide RIA 13-PPTHU-R100 6.25–200 pmol/L 3 pmol/L 100 µL Serum Overnight
Pepsinogen I ELISA 43-PE1HU-E01 3–300 ng/mL 0.1 ng/mL 50 µL Serum 1h 20m
Pepsinogen II ELISA 43-PE2HU-E01 3–300 ng/mL 0.1 ng/mL 50 µL Serum 2h 20m
Proinsulin ELISA 80-PINHU-E01.1 * 2.5–180 pM 1.25 pM 50 µL Heparin Plasma, Serum 2h
Proinsulin Mouse ELISA 80-PINMS-E01 4–300 pM 1.5 pM 10 µL Serum 2h 30m
Proinsulin Rat ELISA 80-PINRT-E01 4–300 pM 1.75 pM 10 µL Serum 2h 30m
PYY ELISA 48-PYYHU-E01.1 0.082–20 ng/mL 0.082 ng/mL 50 µL Plasma, Serum Overnight
PYY Mouse/Rat ELISA 48-PYYRT-E01.1 0.15–12.5 ng/mL 0.31 ng/mL 25 µLEDTA Plasma, Plasma, Serum
Overnight
RBP ELISA 30-6110 5.5–165 µg/mL 0.9 µg/L 20 µL Plasma, Serum, Urine 2h 20m
RBP4 Mouse ELISA 41-RBPMS-E01 0.625–20 ng/mL See Protocol 5 µL Plasma, Serum 1h 10m
RBP4 Rat ELISA 41-RBPRT-E01 6.25–200 ng/mL See Protocol 5 µL Plasma, Serum, Urine 1h 30m
43
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Resistin Rat ELISA 32-5179 0.25–20 ng/mL 0.05 ng/mL 10 µL Cell Culture, Serum 2h 30m
Resistin Ultrasensitive ELISA
22-RESHUU-E01 20–1,000 pg/mL 6 pg/mL 20 µLCell Culture, Plasma, Serum
4h
Sclerostin ELISA 04-BI-20492 15–240 pM 2.6 pM 20 µLEDTA Plasma, Heparin Plasma, Serum
Overnight
Sclerostin Mouse ELISA 41-SCLMS-E0137.5–1,200 pg/mL
17.4 pg/mL 15 µL Heparin Plasma, Serum 5h 20m
Serum Amyloid A ELISA 41-SAAHU-E01 0.157–10 ng/mL 0.157 ng/mL 10 µL Plasma, Serum 1h
Serum Amyloid A Mouse ELISA
41-SAAMS-E0131.25–2,000 ng/mL
31.25 ng/mL 5 µL Serum 1h 40m
Somatostatin RIA 13-RB 306 0–125 pmol/L 6 pmol/L 1 mL Plasma Overnight
TNF-α ELISA 45-TNFHU-E05 15–1,500 pg/mL 1.7 pg/mL 100 µLCell Culture, Plasma, Serum
4h
TNF-α ELISA 45-TNFHU-E0115.6–1,500 pg/mL
1.7 pg/mL 100 µLCell Culture, Plasma, Serum
4h
TNF-α Monkey ELISA 61-TNAMK-E01 28.1–1,800 U/mL 6 U/mL 50 µL Cell Culture, Serum 3h 10m
STELLUX™ Rodent Insulin ELISAALPCO’s STELLUX™ Rodent Insulin ELISA, has a
broad dynamic range that significantly reduces sample
preparation time by eliminating dilution steps and the
guesswork involved in determining ideal dilution factors.
The STELLUX™ Rodent Insulin ELISA can be run with
either mouse or rat samples, as it detects isoforms of both
rodent insulin genes. With no cross-reactivity to c-peptide
or proinsulin, this assay’s results are dependable and
accurate.
• Broad range of 0.1 – 150 ng/mL
• Small sample size of 5 µL
• 2 hour incubation
Inter-Lab Correlation Study with
STELLUX™ Rodent Insulin ELISA (r2 value>0.99)
Inter-Lab Correlation Study
0.1 1 10 100 1000
0.1
1
10
100
1000Lab A
Lab B
Lab C
ALPCO Sample Results (ng/mL)
Off
-sit
e La
bo
rato
ry S
amp
le R
esu
lts
(ng/
mL)
View the STELLUX assay 80-INSMR-CH01 on page 41
Diabetes & Obesity
44
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
TNF-α Mouse ELISA 61-TNFMS-E0115.6–1,000 pg/mL
3 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
4h 10m
TNF-α Porcine ELISA 45-TNFPO-E01.123.4–1,500 pg/mL
4 pg/mL 50 µLCell Culture, EDTA Plasma, Serum
5h
TNF-α Rat ELISA 61-TNART-E0139.1–2,500 pg/mL
11 pg/mL 50 µL Cell Culture, Serum 3h 10m
TNF-α Ultrasensitive ELISA 45-TNFHUU-E01 0.5–32 pg/mL 0.09 pg/mL 50 µLCell Culture, Plasma, Serum
3h
TNF-α Ultrasensitive ELISA 45-TNFHUU-E05 0.5–32 pg/mL 0.09 pg/mL 50 µLCell Culture, Plasma, Serum
3h
Vaspin ELISA 22-VASHU-E01 10–1,000 pg/mL 4 pg/mL 70 µL Serum 3h 30m
45
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Endocrinology
46
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Endocrinology is the field of study which encompasses the functions of the endocrine
system, its complex array of hormones and associated disorders. The endocrine
system is comprised of a vast network of glands and chemically diverse messengers
that interact to regulate coordinated activities with the nervous system in virtually all
tissues. These chemical signaling molecules are called hormones, and they are classified
by their different molecular structures.
Endocrine glands such as sweat,
sebaceous, mucous and digestive,
secrete hormones into ducts which
deliver them to other parts of the
body. At the same time, exocrine
glands like the pituitary, thyroid,
parathyroid and adrenals, secrete
hormones into the extracellular
space and are transported via
capillaries to the blood. Organs that
have an endocrine function include
the pancreas, testes, ovaries,
kidneys, stomach, small intestine,
skin, heart and placenta.
Endocrine System
The endocrine system has five
broad functions:
• Maintain fluid and chemical
homeostasis
• Regulate energy metabolism
and balance
• Govern adaptation to
environmental stimuli such as
trauma and stress
• Integrate coordinated
development
• Support reproductive
processes, from fertilization
to birth and nourishment of
the newborn
Hormones
Hormones fall into three categories:
• Amines, such as the
catecholamines and thyroid
hormones, contain a tyrosine
backbone and are the simplest
type of hormone
• Protein and peptide hormones
are chains of amino acids
of varying length (including
oxytocin and insulin)
• Steroid hormones are derived
from cholesterol, lipid soluble,
and include the reproductive
hormones, glucocorticoids
and mineralcorticoids
Endocrinology
47
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
1,25 (OH)2 Vitamin D Extraction Kit
30-KM1100 See Protocol See Protocol 500 µL Plasma, Serum 1h 8m
17 ß Estradiol ELISA (Saliva) 33-10230 1–100 pg/mL 0.5 pg/mL 100 µL Saliva 2h 15m
17-α-Hydroxy Progesterone ELISA
20-17OHU-E01 * 0.15–20 ng/mL 0.034 ng/mL 25 µL Serum 1h 35m
17-α-Hydroxy Progesterone ELISA (Saliva)
20-17OHU-E01-SLV * 0.005–5 ng/mL 0.003 ng/mL 25 µL Saliva 1h 15m
25-OH Vitamin D HPLC 30-3400 4–1,250 nmol/L 4 nmol/L 500 µL Plasma, Serum See Protocol
5a-Androstane-3a, 17b-diol Glucuronide ELISA
11-ANDHU-E01 0.25–50 ng/mL 0.1 ng/mL 50 µL Serum 45m
5a-Androstane-3a, 17b-diol Glucuronide LIA
11-ANDHU-L01 0.25–50 ng/mL 0.1 ng/mL 50 µL Serum 30m
α-1-Antichymotrypsin ELISA
41-A1CHU-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 30m
α-MSH RIA 13-RB 303 4.7–150 pmol/L 3 pmol/L 100 µLCerebrospinal Fluid, Plasma
Overnight
ß Endorphin RIA 13-RB 301 15.6–500 pmol/L 3 pmol/L 3 mL Plasma Overnight
ß hCG Free ELISA 25-FBEHU-E01 2.5–50 ng/mL 0.25 ng/mL 50 µL Serum 1h 20m
ACE Kinetic 01-KK-ACK * ^ 3–150 ACE units 5 ACE Units 25 µL Serum 15m
ACE Kinetic 01-KK-ACK2 * ^ 3–150 ACE Units 5 ACE Units 25 µL Serum 15m
ACE Kinetic Jumbo (1200) 01-KK-ACKX * ^ 3–150 ACE units 5 ACE Units 25 µL Serum 15m
Acid Labile Subunit ELISA 22-ALS-E35 1.5–40 mU/mL 0.23 mU/mL 5 µL Serum 3h
ACTH ELISA 21-ACTHU-E01 * 5–500 pg/mL 0.46 pg/mL 200 µL Plasma 5h
Active Renin RIA 72-RENINE * 0–320 pg/mL 1 pg/mL 300 mL Plasma 3h
AFP ELISA 25-AFPHU-E01 5–300 ng/mL 2 ng/mL 20 µL Serum 1h 20m
Aldosterone ELISA 11-ALDHU-E01 20–2,000 pg/mL 15 pg/mL 100 µL Serum, Urine 1h 15m
Aldosterone LIA 11-ALDHU-L01 20–2,000 pg/mL 4.24 pg/mL 200 µL Serum, Urine 35m
Aldosterone RIA 72-ALDO-RIACT 7–1,500 pg/mL 7 pg/mL200 µL, 200 µL, 10 µL
Plasma, Serum, Urine 3h
Androstenedione ELISA 11-ANRHU-E01 * 0.1–10 ng/mL 0.04 ng/mL 25 µL Serum 1h 15m
Angiotensin II ELISA 32-5880 1–125 pg/mL 1 pg/mL 100 µL Plasma Overnight
Angiotensin II RIA 01-RK-A22 * 2–500 pg/mL 1 pg/mL 1 mL Plasma Overnight
Anti-Sperm Antibody ELISA 20-ASAHU-E01 62–500 U/mL 62 U/mL 10 µL Plasma, Serum 1h 30m
Anti-TG LIA 14-HD-102.1 * 20–2,000 U/mL 8.2 U/mL 20 µL Serum 2h
Endocrinology
48
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Anti-TPO LIA 14-HD-103.1 * 30–3,000 U/mL 16.7 U/mL 20 µL Serum 2h
Calcitonin ELISA 21-CALHU-E01 * 10–1,000 pg/mL 1 pg/mL 100 µL Serum 4h 30m
Calcitonin Mouse/Rat IRMA 31-CALRT-R100 12–1,800 pg/mL 0.6 pg/mL 200 µLCell Culture, Plasma, Serum
Overnight
CCK RIA 13-CCKHU-R100 0.78–25 pmol/L 0.3 pmol/L 1 mL Plasma Overnight
Chromogranin A ELISA 43-CHRHU-E01.2 31–830 ng/mL 5 ng/mL 50 µL EDTA Plasma 2h 20m
Chromogranin A RIA 13-RB 321 0.156–5 nmol/L 0.04 nmol/L 50 µL Plasma Overnight
c-Met ELISA (HGFR) 48-CMTHU-E01 0.78–50 ng/mL 0.26 ng/mL 100 µLCell Culture, EDTA Plasma, Plasma, Serum
2h
Corticosterone Mouse/Rat ELISA
55-CORMS-E01 15–2,250 ng/mL 4.5 ng/mL 10 µL Plasma, Serum 2h 30m
Cortisol ELISA 11-CORHU-E01 0.5–60 µg/dL 0.4 µg/dL 20 µL Serum 1h
Cortisol ELISA (Saliva) 11-CORHU-E01-SLV 1–100 ng/mL 1 ng/mL 50 µL Saliva 1h
Cortisol ELISA (Urinary) 33-10110 10–500 ng/mL 10 ng/mL 10 µL Urine 1h 15m
DHEA ELISA 20-DHEHU-E01 * 0.37–30 ng/mL 0.108 ng/mL 10 µL Serum 1h 15m
DHEA-S ELISA 11-DHEHU-E01 * 0.005–10 µg/mL 5 pg/mL 25 µL Serum 1h
DHEA-S Salivary ELISA 33-10250 0.2–12 ng/mL 0.045 ng/mL 50 µL Saliva 30m
DHT ELISA 11-DHTHU-E01 25–2,500 pg/mL 6 pg/mL 50 µL Serum 1h 15m
EPO ELISA 21-EPOHU-E01 * 3–500 mIU/mL 0.6 mIU/mL 400 µL Serum 2h 30m
Estradiol 17 ß ELISA 48-ESTHU-E0116.5–4,000 pg/mL
16.5 pg/mL 100 µL Water Overnight
Estradiol ELISA 11-ESTHU-E01 * 20–3,200 pg/mL 10 pg/mL 50 µL Serum 1h 15m
Estradiol RIA 72-ESTR-CTRIA 8–5,000 pg/mL 8 pg/mL 100 µL Plasma, Serum 4h
Estradiol Ultrasensitive ELISA
20-ESTHUU-E01 * 3–200 pg/mL 3 pg/mL 100 µL Plasma, Serum 4h 30m
Estradiol Ultrasensitive RIA 72-ESTR-US-CT 10–2,000 pmol/L 5 pmol/L 200 µLEDTA Plasma, Heparin Plasma, Plasma, Serum
2h
Estriol ELISA (Saliva) 33-10270 2.5–4,000 pg/mL 1.1 pg/mL 50 µL Saliva 1h 15m
Estriol Free ELISA 20-FE3HU-E01 * 0.3–40 ng/mL 0.075 ng/mL 10 µL Serum 1h 30m
Estrone ELISA 11-ESRHU-E01 * 15–2,000 pg/mL 10 pg/mL 50 µL Serum 1h 15m
Estrone LIA 11-ESRHU-L01 15–2,000 pg/mL 8.8 pg/mL 50 µL Serum 40m
Estrone-3-Sulfate Equine ELISA
55-E3SEQ-E01 5–1,000 ng/mL 0.14 ng/mL 20 µL Serum 30m
Ferritin ELISA 25-FERHU-E01 * 15–1,000 ng/mL 5 ng/mL 20 µL Serum 1h 5m
49
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
FGF Basic ELISA 45-FGFHU-E0115.6–1,000 pg/mL
7 pg/mL 50 µLCell Culture, Plasma, Serum
4h
FSH ELISA 11-FSHHU-E01 * 5–100 IU/L 1 IU/L 25 µL Serum 1h 20m
Glutathione HPLC (GSH/GSSG)
30-1800 620–970 µmol/L 6 µmol/L 100 µL EDTA Plasma, Plasma See Protocol
Growth Hormone Human ELISA
25-HGHHU-E01 * 2.5–50 ng/mL 0.5 ng/mL 50 µL Serum 1h
Growth Hormone Human RIA
72-HGH-RIACT 0.03–75 µIU/mL 0.03 µIU/mL 50 µL Serum 2h 30m
Growth Hormone Mouse/Rat ELISA
22-GHOMS-E01 0.025–1.5 ng/mL 0.025 ng/mL 10 µL Plasma, Serum 3h
Growth Hormone Rat ELISA 32-5104 0.31–40 ng/mL 0.5 ng/mL 50 µLCell Culture, Plasma, Serum
Overnight
hCG ELISA 25-HCGHU-E01 * 5–300 mIU/mL 2 mIU/mL 50 µL Serum 1h
Hepcidin 25 LC-MS 30-KM4000 See Protocol 1 ng/mL See Protocol Serum See Protocol
Hepcidin ELISA (25 C-Terminal)
20-HCTHU-E01 2–80 ng/mL 2 ng/mL 20 µL Plasma, Serum 1h 50m
IGF-1 ELISAInsulin-like Growth Factor 1 (IGF-1,
Somatomedin C) is one of several
growth factors necessary for normal
human development. ALPCO’s IGF-1
ELISA is an FDA registered kit which
provides results in-line with leading
clinical methods.
IGF-1 is synthesized mainly by the
liver, but also locally in many tissues. In contrast to many other peptide hormones, IGFs are avidly bound to specific
IGFBPs, which significantly increases the half-life of IGF-I in circulation. The seven classes of IGFBPs which are known
at present 1, 2, 3 either bind IGF-I and IGF-II with similar affinities or show a preference for IGF-II. 4, 5 The predominant
measured IGF-I [pg/tube]
actual IGF-I[pg/tube]
10000
1000
100
10
11 10 10 100 1000 10000
conventional
0.5 ng IGFBP-3
ALPCO
measured IGF-I [pg/tube]
actual IGF-I[pg/tube]
10000
1000
100
10
11 10 10 100 1000 10000
conventional
5 ng IGFBP-3
ALPCO
Minimal interference of IGFBP in IGF-I measurements
with ALPCO assay versus conventional method
Endocrinology
50
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
1 Ballard J, Baxter R, Binoux M, et al. On the nomenclature of the IGF binding proteins. Acta Endocrinology. Nov 1989; Vol 121: 751-752.
2 Drop SLS. Report on the nomenclature of the IGF binding proteins. J Clin Endocrinology & Metabolism. Mar 1990; Vol 70 No 3: 817-818.
3 Wilson EM, Oh Y, Rosenfeld RG. Generation and characterization of an IGFBP-7 antibody: Identification of 31 kD IGFBP-7 in human biological fluids and
Hs578T human breast cancer conditioned media. J Clin Endocrinology & Metabolism. Apr 1997. Vol 82 No 4:1301-1303.
4 Martin JL, Baxter RC. Insulin-like growth factor binding protein from human plasma. Purification and characterization. J Biol Chem. Jul 1986; Vol 261: 8754-8760.
5 Binkert C, Landwehr J, Mary JL, et al. Cloning, sequence analysis and expression of a cDNA encoding a novel insulin-like growth factor binding protein
(IGFBP-2). EMBO J. Sep 1989; Vol8 No9: 2497-2502.
View the IGF-1 ELISA assay 22-IGFHU-E01 on page 51
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Hepcidin Prohormone ELISA
20-HEPHU-E01 10–1,000 ng/mL 4 ng/mL 50 µL Serum, Urine 3h 30m
Homocysteine ELISA 66-HCYHU-E01 2–50 µmol/L 1 µmol/L 25 µL EDTA Plasma, Serum See Protocol
HPL ELISA 20-HPLHU-E01 1.25–20 mg/L 0.3 mg/L 10 µL Serum 40m
Human Growth Hormone Ultrasensitive ELISA
22-HGHHUU-E01 * 50–1,000 pg/mL 1.6 pg/mL 10 µL Plasma, Serum 3h 15m
IGF-1 Direct RIA 22-IGF-R20 * 0.156–10 ng/mL 0.02 ng/mL 5 µLCell Culture, Plasma, Serum
Overnight
IGF-1 Direct RIA 22-IGF-R21 * 0.156–10 ng/mL 0.02 ng/mL 5 µLCell Culture, Plasma, Serum
Overnight
IGF-1 Direct RIA (Coated Tube)
22-IGF-R22 * 0.37–30 ng/mL 0.1 ng/mL 10 µL Plasma, Serum Overnight
IGF-1 ELISA 22-IGFHU-E01 * 2–50 ng/mL 0.09 ng/mL 10 µL Plasma, Serum 1h 45m
IGF-1 Mouse/Rat ELISA 22-IG1MS-E01 0.5–18 ng/mL 0.029 ng/mL 5 µL Plasma, Serum 2h
IGF-1 RIA 72-IGF1-RIACT 0–835 ng/mL 1 ng/mL 25 µL Plasma, Serum 4h 30m
IGFBP is IGFBP-3, which binds not only IGF-I but also the
Acid-labile Subunit. Thus, most of the IGF-I in circulation
is bound within this ternary complex. IGFBPs can make
the measurement of IGF-I very difficult, because if the
right methodology is not used, the IGFBPs become
interferents in the assay. With ALPCO’s IGF-1 ELISA,
there is no interference from IGFBP-3 so values can be
trusted, and it is traceable to international reference
material of the WHO 02/254.
51
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
IGF-2 ELISA 22-IGF-E30 0.45–9 ng/mL 0.02 ng/mL 5 µLCerebrospinal Fluid, Plasma, Serum, Stool, Urine
3h
IGF-2 RIA 22-IGF-R30 0.4–50 ng/mL 0.1 ng/mL 10 µLCell Culture, Plasma, Serum
Overnight
IGF-2 RIA 22-IGF-R31 0.4–50 ng/mL 0.1 ng/mL 10 µLCell Culture, Plasma, Serum
Overnight
IGFBP-1 ELISA 11-IGFHU-E01 1–250 µg/L 0.5 µg/L 25 µL Serum 1h 10m
IGFBP-2 ELISA 22-IGF-E05 2–80 ng/mL 0.2 ng/mL 15 µLBreast Milk, Cell Culture, EDTA Plasma, Plasma, Saliva, Serum
1h 45m
IGFBP-2 Mouse/Rat ELISA 22-MIGF-E0831.25–2,000 pg/mL
0.01 ng/mL 10 µL Serum 2h 30m
IGFBP-3 ELISA 22-IGF-E03A 6.6–20 ng/mL 6.6 ng/mL 10 µL Plasma, Serum 2h 30m
IGFBP-3 ELISA (Bioactive) 22-IGF-E04A 0.4–30 ng/mL 2 ng/mL 50 µLEDTA Plasma, Heparin Plasma, Plasma, Serum
3h 30m
IGFBP-3 Mouse/Rat ELISA 22-MIGF-E031 0.078–5 ng/mL 0.018 ng/mL 5 µLCell Culture, Plasma, Serum
2h 30m
IGFBP-3 RIA 22-IGF-R10 0.625–40 ng/mL 0.06 ng/mL 50 µL Plasma, Serum Overnight
IGFBP-3 RIA (Coated Tube) 22-IGF-R11 1–81 ng/mL 0.5 ng/mL 10 µL Plasma, Serum Overnight
Intact PTH Bovine ELISA 31-IPTBO-E01 0–10,000 pg/mL 10 pg/mL 50 µLCell Culture, Plasma, Serum
3h 30m
Luteinizing Hormone ELISA 11-LUTHU-E01 * 1–100 IU/L 0.2 IU/L 25 µL Serum 1h 20m
Lutenizing Hormone ELISA (Urine)
20-LHUHU-E01 10–200 mIU/mL 10 mIU/mL 25 µL Urine 40m
Myostatin ELISA 30-1012 0.27–195 ng/mL 0.27 ng/mL 30 µL Plasma, Serum 5h
PAPP-A Ultrasensitive ELISA
55-PAPHUU-E0111.25–450 ng/mL
0.023 ng/mL 100 µL Serum 45m
PMSG ELISA 20-PMSHU-E01 See Protocol See Protocol 100 µL Plasma, Serum 2h 30m
Prealbumin ELISA 30-6331 1.6–100 ng/mL 3 ng/mL 100 mg Plasma, Serum, Stool 2h 15m
Prealbumin Mouse ELISA 41-PALMS-E0115.625–500 ng/mL
15.625 ng/mL 5 µL Plasma, Serum 1h
Prealbumin Rat ELISA 41-PALRT-E0115.625–500 ng/mL
15.625 ng/mL 5 µL Plasma, Serum 1h
Pregnenolone ELISA 11-PREHU-E01 * 0.1–25.6 ng/mL 0.05 ng/mL 50 µL Serum 1h 45m
Progesterone ELISA 11-PROHU-E01 * 0.3–60 ng/mL 0.1 ng/mL 25 µL Serum 1h 10m
Progesterone ELISA (Direct Saliva)
11-PROHU-E01-SLV 20–5,000 pg/mL 20 pg/mL 1 mL Saliva 1h 10m
Progesterone LIA 11-PROHU-L01 0.3–100 ng/mL 0.1 ng/mL 25 µL Serum 35m
Endocrinology
52
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Progesterone Mouse/Rat ELISA
55-PROMS-E01 0.4–100 ng/mL 0.04 ng/mL 25 µL Plasma, Serum 1h 30m
Progesterone RIA 72-PROG-CTRIA 0.1–60 ng/mL 0.05 ng/mL 50 µLEDTA Plasma, Heparin Plasma, Plasma, Serum
2h 10m
Prolactin Canine ELISA 55-PRLCA-E01 2.5–80 ng/mL 0.4 ng/mL 25 µL Serum 3h 30m
Prolactin ELISA 25-PROHU-E01 * 5–200 ng/mL 2 ng/mL 50 µL Serum 1h 5m
Prolactin Rat ELISA 55-PRLRT-E01 5–80 ng/mL 0.6 ng/mL 25 µL Serum 3h 30m
PSA Total ELISA 25-PSAHU-E01 2–120 ng/mL 1 ng/mL 50 µL Serum 2h 20m
PTH Bioactive Intact Rat ELISA
31-BIPRT-E01 25–2,700 pg/mL 3 pg/mL 25 µL Cell Culture, Plasma 3h 30m
PTH High Sensitive ELISA (1-34)
31-IPTHUU-E01 3.2–143 pg/mL 0.3 pg/mL 150 µLCell Culture, EDTA Plasma, Plasma
3h 30m
PTH Intact ELISA (1-84) 21-IPTHU-E01 * 7–700 pg/mL 1.57 pg/mL 25 µL Serum 3h 30m
PTH Intact Mouse ELISA (1-84)
31-PTHMS-E0132–1,045 pg/mL or 336–2,616 pg/mL
4 pg/mL 20 µL Cell Culture, Plasma 3h 30m
PTH Intact Porcine ELISA 31-IPTPO-E01 0–1,000 pg/mL 1 pg/mL 50 µLCell Culture, Plasma, Serum
3h 30m
PTH Intact Rat ELISA (1-84) 31-IPTRT-E01 25–2,700 pg/mL 1.6 pg/mL 25 µLCell Culture, Plasma, Serum
3h 30m
Relaxin ELISA 30-9210 4–250 pg/mL 4 pg/mL 100 µLPlasma, Serum, Tissue Culture, Urine
Overnight
Renin Activity ELISA 11-RENHU-E02 0.2–60 ng/mL 0.038 ng/mL 50 µL EDTA Plasma, Plasma 1h 45m
Renin Activity LIA 11-RENHU-L02 0.2–25 ng/mL 0.08 ng/mL 500 µL EDTA Plasma, Plasma 1h 30m
Renin ELISA 20-RENHU-E01 0.81–28 pg/mL 0.81 pg/mL 50 µL EDTA Plasma 3h 15m
Reverse T3 RIA 38-RT3HU-R125 0.025–2 ng/mL 0.009 ng/mL 100 µLAmniotic Fluids, Plasma, Serum
3h
SHBG ELISA 11-SHBHU-E01 3.3–295 nmol/L 0.1 nmol/L 10 µL Serum 1h
Somatostatin RIA 13-RB 306 0–125 pmol/L 6 pmol/L 1 mL Plasma Overnight
T3 Free ELISA 25-FT3HU-E01 0.9–19 pg/mL 0.05 pg/mL 50 µL Serum 1h 20m
T3 Total ELISA 25-TRIHU-E01 * 0.75–10 ng/mL 0.2 ng/mL 50 µL Serum 1h 20m
T3 Total RIA 14-HD-131.100 0.8–10 nmol/L 0.3 nmol/L 50 µL Serum 2h
T4 Free ELISA 25-FT4HU-E01 0.3–7 ng/dL 0.05 ng/dL 50 µL Serum 1h 20m
T4 Free LIA 11-FT4HU-L01 0–120 pg/mL 1 pg/mL 50 µL Serum 45m
T4 Total ELISA 25-TT4HU-E01 * 2–25 µg/dL 0.4 µg/dL 25 µL Serum 1h 20m
T4 Total RIA 14-HD-141.100 25.6–512 nmol/L 12.8 nmol/L 50 µL Serum 2h
53
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
TBG RIA 14-HD-53.1 5–80 mg/L 5 mg/L 20 µL Serum 2h
Testosterone Direct Saliva ELISA
11-TESHU-E01-SLV 2–800 pg/mL 1 pg/mL 1 mL Saliva 1h 40m
Testosterone ELISA (Serum) 11-TESHU-E01 * 0.08–16.7 ng/mL 0.022 ng/mL 50 µL Serum 1h 10m
Testosterone Free ELISA 11-FTSHU-E01 * 0.25–125 pg/mL 0.17 pg/mL 25 µL Serum 1h 15m
Testosterone Free LIA 11-FTSHU-L01 0.25–100 pg/mL 0.17 pg/mL 25 µL Serum 1h
Testosterone LIA (Saliva) 11-TESHU-L01 2–800 pg/mL 1 pg/mL 1 mL Saliva 1h 10m
Testosterone Mouse/Rat ELISA
55-TESMS-E01 0.1–25 ng/mL 0.066 ng/mL 10 µL Plasma, Serum 30m
Testosterone RIA 72-TESTO-CT2 0.5–50 nmol/L 0.3 nmol/L 25 µL Serum 1h
Thyroglobulin Ab RIA 14-HD-27.1 * 20–2,000 IU/mL 5.5 IU/mL 20 µL Plasma, Serum 2h
Thyroglobulin ELISA 27-GD101 10–400 ng/mL 2 ng/mL 50 µL Serum 1h 40m
Thyroglobulin Plus ILMA 14-HD-111.1 0.15–250 ng/mL 0.02 ng/mL 100 µL Serum Overnight
Thyroglobulin Plus IRMA 14-HD-110.1 * 0.15–250 ng/mL 0.2 ng/mL 100 µL Serum 1h 20m
TPO Ab RIA 14-HD-90.1 * 30–3,000 U/mL 5.5 U/mL 90 µL Serum 1h
TSH Canine ELISA 55-TSHCA-E01 0.2–5.2 ng/mL 0.01 ng/mL 100 µLEDTA Plasma, Plasma, Serum
2h 30m
TSH ELISA 25-TSHHU-E01 * 0.5–25 µIU/mL 0.2 µIU/mL 100 µL Serum 1h 20m
TSH IRMA 14-HD-09.1 0.16–80 MU/L 0.04 mU/L 100 µL Serum 1h
TSH LIA 11-TSHHU-L01 0.008–25 µIU/mL 0.002 µIU/mL 50 µL Serum 1h
TSH Rat ELISA 55-TSHRT-E01 0.1–80 ng/mL 0.1 ng/mL 25 µL Serum Overnight
TSH Receptor Autoantibodies LRA
14-HD-107.1 * 1–40 IU/L 0.4 IU/L 100 µL Serum 3h
TSH Receptor Autoantibodies RIA
14-HD-77.1 5–405 U/L 2.4 U/L 50 µL Serum 2h 15m
TSH RRA Receptor Ab RIA 14-HD-101.1 1–40 IU/L 0.3 IU/L 100 µL Serum 3h
TSH Ultrasensitive ELISA 25-TSHHUU-E01 * 0.1–10 µIU/mL 0.05 µIU/mL 100 µL Serum 2h 20m
Vasoactive Intestinal Peptide RIA
13-RB 311 3.8–120 pmol/L 3 pmol/L 200 µL Serum Overnight
Vasopressin Direct RIA (ADH/AVP)
01-RK-VPD ^ 1.25–80 pg/mL 0.75 pg/mL 1 mL EDTA Plasma Overnight
Vasopressin Ultrasensitive RIA (ADH/AVP)
01-RK-AR1 0.63–80 pg/mL 0.4 pg/mL 1 mL EDTA Plasma, Urine Overnight
Vitamin D2/D3 HPLC 30-3420 4–1,250 nmol/L 4 nmol/L 500 µL Plasma, Serum See Protocol
Endocrinology
54
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
56
Gastroenterology
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Gastroenterology is the branch of medicine that deals with the study and treatment
of the digestive system (comprised of stomach and intestine) and related disorders
affecting it. Gastric diseases and ailments have become a growing therapeutic segment
of interest due to an increased prevalence of irregular dietary habits and poor hygiene
factors across the world.
Calprotectin is considered a reliable indicator of
inflammation in several diseases. Both organic
Inflammatory Bowel Disease (IBD) and non-organic
functional disorders like Irritable Bowel Syndrome
(IBS) exhibit very similar symptoms. Research has
shown the concentration of calprotectin in feces may
be significantly elevated in cases of IBD, whereas
in cases of IBS, levels remain normal. 1,2,3 Thus,
measurement of fecal calprotectin may be useful for
the differential diagnosis and potential management
of organic Inflammatory Bowel Disease. 4,5,6
Measurement of fecal calprotectin levels may provide
physicians with valuable information for timely
decision making on whether to send IBD patients for
colonoscopy, or rather treat them for IBS symptoms.
Traditionally, IBD activity has been assessed through
Calprotectinclinical symptoms, but it has been reported that the
recognized activity indexes are subjective and do not
correlate as consistently as fecal calprotectin levels with
histologic inflammation.7,8
Fecal calprotectin has been demonstrated to be
a reliable biomarker of mucosal inflammation in
several organic IBD pathologies and may function as
a valuable alternative to relying on clinical symptoms,
the use of complex imaging procedures, or performing
endoscopy and/or biopsy. Because of the strong
correlation between calprotectin and disease activity,
many research studies conclude that monitoring fecal
calprotectin levels can be useful for chronicling disease
activity in IBD.7,8,9 Increased levels of calprotectin as an
indicator of inflammation also precedes the appearance
of clinical symptoms.
57
Research has shown that IBD is marked by periods of
remission with intermittent relapses characterized by
increased intestinal inflammation. Thus, monitoring levels
of fecal calprotectin may become essential in determining
the effectiveness of therapy and could become a predictor
of potential relapse. It provides physicians with a valuable
tool, not only for differentiating IBD from IBS cases, but
also allowing them to monitor and predict treatment
outcomes, enabling better management of IBD flares.4-12
1 Røseth AG, Fagerhol MK, Aadland E, Schjønsby H. Assessment of the
neutrophil dominating protein calprotectin in feces. A methodologic study.
Scand J Gastroenterology. Sep 1992; Vol 27 No 9:793-8.
2 Manz M, Burri E, Rothen C, Tchanguizi N, et al. Value of fecal calprotectin
in the evaluation of patients with abdominal discomfort: an observational
study. BMC Gastroenterology. Jan 2012; Vol 12 No 1:5.
Differentiation of IBD vs. IBS
Fecal calprotectin is a reliable surrogate marker for
differentiating organic inflammation (IBD) from functional
symptoms (IBS). 4-12
Predicting Relapse
Calprotectin has been shown in numerous publications to
be a reliable predictor of IBD in remission. 4-12
Disease Monitoring
Low calprotectin levels after treatment (<250 µg/g)
indicate endoscopic mucosal healing. This can assist in
optimizing treatment in IBD patients. 4-12
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
α-1-Antichymotrypsin ELISA
41-A1CHU-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 30m
α-1-Antitrypsin Mouse ELISA
41-A1AMS-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Serum 2h 5m
α-Fodrin Check IgG/IgA ELISA
35-AFCHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
1,25 (OH)2 Vitamin D ELISA 30-2112 5.1–200 pg/mL 4.8 pg/mL 500 µL Plasma, Serum Overnight
1,25 (OH)2 Vitamin D Extraction Kit
30-KM1100 See Protocol See Protocol 500 µL Plasma, Serum 1h 8m
25-OH Vitamin D ELISA 30-2109 2–300 nmol/L 2 nmol/L 30 µL Serum Overnight
25-OH Vitamin D HPLC 30-3400 4–1,250 nmol/L 4 nmol/L 500 µL Plasma, Serum See Protocol
58
Gastroenterology
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Alpha-1 Thymosin ELISA 30-9510 4–1,000 ng/mL 4 ng/mL 200 µL Serum, Tissue Culture Overnight
Anti-Casein IgA ELISA 27-GD42Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-Gliadin IgA ELISA 27-GD17 6.25–100 U/mL 0.25 U/mL 10 µL Serum 1h 10m
Anti-Gliadin IgA/IgG ELISA 27-GD77 6.25–100 U/mL 0.5 U/mL 10 µL Plasma, Serum 1h 10m
Anti-Gliadin IgG ELISA 27-GD16 6.25–100 U/mL 0.25 U/mL 10 µL Serum 1h 10m
Anti-Helicobacter Pylori IgA ELISA
27-GD08Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-Helicobacter Pylori IgG ELISA
27-GD01 6.25–100 U/mL 6.25 U/mL 10 µL Plasma, Serum 1h 10m
3 Røseth AG, Schmidt PN, Fagerhol MK. Correlation between faecal excretion
of indium-111-labelled granulocytes and calprotectin, a granulocyte
marker protein, in patients with inflammatory bowel disease. Scand J
Gastroenterology. Jan 1999; Vol 34 No1:50-4.
4 Tibble J.A., Bjarnason I. et al. Surrogate markers of intestinal inflammation
are predictive of relapse in patients with inflammatory bowel disease.
Gastroenterology Jul 2000; Vol 119 No 1: 15-22.
5 Røseth AG, Aadland E, Grzyb K. Normalization of faecal calprotectin: a
predictor of mucosal healing in patients with inflammatory bowel disease.
Scand J Gastroenterology. Oct 2004; Vol 39 No 10: 1017-1020.
6 Lewis, JD. The utility of biomarkers in the diagnosis and therapy of
inflammatory bowel disease. Gastroenterology. May 2011; Vol 140 No 6:
1817-1826.
7 Burri E, Beglinger C. Faecal calprotectin - a useful tool in the management of
inflammatory bowel disease. Swiss Med Weekly. Apr 2012; Vol 142.
8 D’Haens G, Ferrante M, et al. Fecal calprotectin is a surrogate marker for
endoscopic lesions in inflammatory bowel disease. Inflamm Bowel Disease.
Feb 2012. Vol 18 No 12: 2218-24.
9 Lobatón T, Rodríguez-Moranta F, Lopez A, et al. A new rapid quantitative
test for fecal calprotectin predicts endoscopic activity in ulcerative colitis.
Inflamm Bowel Disease. Apr 2013. Vol 19 No 5: 1034-1042.
10 Louis E, Mary JY, Vernier-Massouille G, et al. Maintenance of remission
among patients with Crohn’s disease on antimetabolite therapy after
infliximab therapy is stopped. Gastroenterology. Jan 2012; Vol 142 No 1:
63-70.
11 De Vos M, Dewit O, D’Haens G, et al. Fast and sharp decrease in calprotectin
predicts remission by infliximab in anti-TNF naïve patients with ulcerative
colitis. J Crohns Colitis. Jun 2012; Vol 6 No 5: 557-62.
12 Sorrentino D, Terrosu G, Paviotti A, et al. Early diagnosis and treatment of
postoperative endoscopic recurrence of Crohn’s disease: partial benefit by
infliximab--a pilot study. Digestive Diseases and Sciences. May 2012; Vol 57
No 5: 1341-1348.
59
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
View calprotectin assays 01-EK-CAL, 01-LF-CHR25, 01-LF-CAL25, and 01-DS-CAL25 on page 60
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Anti-Helicobacter Pylori IgM ELISA
27-GD124Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum 1h 10m
Anti-Helicobacter Pylori Qualitative IgG ELISA
27-GD21Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 50m
Anti-Human Tissue Transglutaminase
sIgA ELISA30-9393
Cut-off: See Protocol
See Protocol 100 mg Stool 2h 30m
Anti-Ovalbumin IgA ELISA 27-GD40Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-Ovalbumin IgG ELISA 27-GD41Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-Soya IgA ELISA 27-GD44Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-TNF α Inhibitor ELISA (Antibody
Against ENBREL®)30-9653
Cut-off: See Protocol
See Protocol 100 µL Serum Overnight
Anti-TNF α Inhibitor ELISA (Antibody Against Humira®)
30-9652Cut-off: See Protocol
See Protocol 100 µL EDTA Plasma, Serum Overnight
Biotin ELISA 30-8140 37.5–600 ng/L 15 ng/L 150 µL Serum, Urine 1h 15m
Biotin Microbiological Assay
30-KIF007 0.02–0.18 µg/L 0.02 µg/L 100 µL Serum Overnight
Calprotectin CALcheck Blue™ Dipstick (25 tests)
01-DS-CAL25Cut-off: See Protocol
See Protocol See Protocol Stool 10m
Calprotectin ELISA 01-EK-CAL ^ † 10–600 µg/g or 30–1,800 µg/g
10 µg/g 50 mg Stool 1h 15m
Calprotectin ELISA (2x96 Wells)
01-EK-CAL-02 ^ 10–600 µg/g or 30–1,800 µg/g
10 µg/g 50 mg Stool 1h 15m
Calprotectin Mouse/Rat ELISA
30-6936 0.25–15.6 ng/mL 0.076 ng/mL 100 µLCell Culture, Plasma, Serum, Stool, Tissue Culture, Urine
4h 20m
Calprotectin Quantum Blue® High Range
Rapid Test01-LF-CHR25 ^ 100–1,800 µg/g 100 µg/g 80 mg Stool 15m
Calprotectin Quantum Blue® Rapid Test
01-LF-CAL25 ^ 30–300 µg/g 10 µg/g 80 mg Stool 12m
Care™ FOB Rapid Testing Kit (20 tests)
43-FOBHU-RP20 * See Protocol0.05 µg h-Hb/mL
See Protocol Stool 5m
Care™ FOB Rapid Testing Kit (50 tests)
43-FOBHU-RP50 * See Protocol0.05 µg h-Hb/mL
See Protocol Stool 6m
Casomorphin ELISA 30-7010 1–120 ng/mL 1 ng/mL 2 mL Urine Overnight
CAST® ELISA (Leukotriene Function)
01-EK-CAST 50–3,200 pg/mL 20 pg/mL 2 mL Whole Blood 2h 30m
60
Gastroenterology
* FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed † Pending FDA Clearance
Products are for Research Use Only unless otherwise noted
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
CAST® ELISA Jumbo (Leukotriene Function)
01-EK-CAST5 50–3,200 pg/mL 20 pg/mL 2 mL Whole Blood 2h 30m
CeliCheck ELISA (Tissue Transglutaminase
IgA/IgG ELISA)35-CELHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h 30m
Chymotrypsin Activity Assay
30-6990 13.2 U/g See Protocol 100 µL Stool 5m
Chymotrypsin ELISA 30-6910 20–1,000 ng/mL 20 ng/mL 100 mg Stool 2h 30m
Crohns Check ELISA (Anti-Saccharomyces
Cerevisiae IgA/IgG ELISA)35-CROHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
DAO ELISA 30-8500 0–15.65 U/mL 0.052 U/mL 50 µL Serum 4h 20m
EDN ELISA 30-6811 0.25–16 ng/mL 0.165 ng/mL 80 mg, 20 µLPlasma, Serum, Stool, Urine
2h 20m
FlowCAST Highsens® High Sensitivity Basophil
Activation Test01-FK-HSBAT ^ See Protocol See Protocol 100 µL Whole Blood 1h
FlowCAST® Basophil Activation Test
01-FK-CCR See Protocol See Protocol 50 µL Whole Blood 30m
Folic Acid Vitamin B9 Microbiological Test Kit
30-KIF005 4–40 µg/L 4 µg/L 100 µL Serum Overnight
Gastrin RIA 13-MD 302 * 15.6–500 pmol/L 5 pmol/L 100 µL Serum 1h 45m
Gastrin RIA 72-GASK-PR 0–500 µU/mL 10 µU/mL 100 µL Plasma, Serum 3h
Gliadorphin ELISA 30-7011 3–30 ng/mL 2 ng/mL 2 mL Urine Overnight
Hemoglobin/Haptoglobin ELISA
30-7817 0.1–3.5 U/L 0.30 U/L 100 mg Stool 2h 20m
Lactoferrin ELISA 41-LACHU-E013.125–100 ng/mL
3.125 ng/mL 5 µL Milk, Plasma, Serum 1h 15m
Lysozyme ELISA 30-6900 1.1–30 ng/mL 0.5 ng/mL 100 mg, 15 mg Stool 2h 20m
Food IntoleranceALPCO offers a number of assays for the measurement of
food-specific proteins such as gliadin, ovalbumin, casein,
and soya. Kits contain reagents which are ready-to-use
and coded to ensure accurate reagent dispensing. The
assays require minimal pipetting steps, making them
convenient for manual processing if needed.
61
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Lysozyme ELISA (Serum, Urine, Liquor)
30-6902 1.1–30 ng/ml 0.5 ng/ml 100 µL See Protocol 2h 20m
MRP 8/14 ELISA 01-EK-MRP8/14 0.4–24 µg/mL 0.4 µg/mL 10 µL Plasma, Serum 1h 15m
Niacin MicroBiological Assay Kit (Vitamin B3)
30-KIF003 4–40 µg/L 4 µg/L 150 µL Serum Overnight
Pepsinogen I ELISA 43-PE1HU-E01 3–300 ng/mL 0.1 ng/mL 50 µL Serum 1h 20m
Pepsinogen II ELISA 43-PE2HU-E01 3–300 ng/mL 0.1 ng/mL 50 µL Serum 2h 20m
q-FOB™ Immunochemical Test (FIT) Kit
43-FOBHU-E01 0–82 ng/mL 2.6 ng/mL 100 µL Stool 40m
Riboflavin Microbiological Assay Kit (Vitamin B2)
30-KIF002 5–60 ng/L 5 ng/L 150 µL Serum Overnight
S100A12 ELISA 30-6938 0.22–6 ng/mL 0.016 ng/mL 100 mg Stool 2h
Secretory IgA ELISA 30-8870 22.2–600 ng/mL 13.4 ng/mL 100 mg, 10 µL Saliva, Stool 2h 10m
Secretory IgA1 ELISA 30-6863 3.3–100 U 3.3 U 100 mg Stool 2h 15m
Secretory IgA2 ELISA 30-6864 3.3–100 U 3.3 U 100 mg Stool 2h 15m
ß Defensin 2 ELISA 30-6500 0.1–3 ng/mL 0.077 ng/mL 100 mg Stool 3h 30m
Thiamin Microbiological Assay Kit (Vitamin B1)
30-KIF001 3–15 ng/L 3 ng/L 100 µL Whole Blood Overnight
Secretory IgASecretory IgA is a marker of intestinal immune status and
is a major immunoglobulin in gastrointestinal secretions.
Secretory IgA is an important factor in mucosal immunity
and in the intraluminal microbial defense system. It plays
a role in preventing adherence of microorganisms to
mucosal sites, in activation of the alternative complement
pathway and in activating inflammatory reactions.
Measuring levels of Secretory IgA may aid in the
understanding of intestinal immune status. A low sIgA-
level may indicate reduced activity of the intestinal
immune system, while an elevated sIgA-level may be
indicative of immune system activation of the gut mucosa
caused by pathogens or allergic processes.1
1 Yel, L. Selective IgA Deficiency. J Clinical Immunology. Jan 2010; Vol 30 No 1: 10–16.
62
Gastroenterology
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
View secretory IgA assays 30-8870, 30-6863, and 30-6864 on page 62
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Vasoactive Intestinal Peptide RIA
13-RB 311 3.8–120 pmol/L 3 pmol/L 200 µL Serum Overnight
Vitamin A and Vitamin E HPLC Assay (Retinol and Tocopherol HPLC Assay)
30-1600 See Protocol 0.05 mg/mL 100 µL EDTA Plasma, Serum See Protocol
Vitamin B1 HPLC 30-2201 12–192 nmol/L 0.13 nmol/L 50 µL Plasma 1h 35m
Vitamin B12 MicroBiological Test Kit
30-KIF012 6–54 µg/L 6 µg/L 75 µL Serum Overnight
Vitamin B5 Pantothenic Acid Microbiological Assay
30-KIF004 0.36–3.6 µg/L 0.36 µg/L 300 µL Serum Overnight
Vitamin B6 Enzymatic Assay
01-KK-VB6 9–250 nM 7 nM 25 µL EDTA Plasma 45m
Vitamin B6 HPLC 30-2100 4.3–17.9 ng/mL 0.2 ng/mL 200 µLEDTA Plasma, Plasma, Serum
See Protocol
Vitamin B6 MicroBiological Assay
30-KIF006 0.36–3.6 µg/L 0.36 µg/L 300 µL Serum Overnight
Vitamin C HPLC (Ascorbic Acid)
30-2900 4–20 mg/L 0.25 mg/L 200 µLHeparin Plasma, Plasma
See Protocol
Vitamin D Binding Protein ELISA
30-2314 2.2–60 ng/mL 1.23 ng/mL 10 µL Plasma, Serum, Urine 2h 20m
Vitamin D Binding Protein Rat ELISA
41-VDBRT-E013.125–100 ng/mL
3.125 ng/mL 5 µL Plasma, Serum 1h 30m
Vitamin K1 HPLC 30-2400 See Protocol 0.15 ng/mL 1 mL Plasma, Serum See Protocol
Zonulin ELISA 30-5600 0–1,000 ng/mL 0.6 ng/mL 250 µL Stool 3h 10m
Zonulin ELISA (Serum) 30-5601 See Protocol 0.6 ng/mL See Protocol Serum 3h 10m
63
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Immunology
64
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Immunology is the branch of biomedical science that is concerned with the relationship
between body systems, pathogens and immunity. The central science of immunology is
the study of the molecular and cellular components that comprise the immune system,
including their function and interaction. ALPCO offers tools that can be used to gain
insight into the development or progression of immune responses.
Innate Immune System
The innate system attempts to
protect the body from all invaders.
The elements of this system include
surface barriers and internal
defenses. The two surface barriers
are skin and mucosae. The skin
provides a nearly impenetrable
barrier to microorganisms and
fluids secreted onto the skin
contain chemicals that inhibit the
growth of microorganisms. Mucous
membranes produce mucus to trap
microorganisms.
The internal defenses consist of cells
and chemicals. The predominant
cell types involved are phagocytes
and natural killer cells. In response
to microorganisms, these cell
types release chemicals and
antimicrobial proteins as a part of
the inflammatory response.
Adaptive Immune System
The adaptive system can initiate
specific attacks against specific
invaders. This system consists of
cells that recognize specific foreign
substances and act to neutralize or
destroy them. Three types of cells
play the major roles in the adaptive
immune system: B lymphocytes (B
cells), T lymphocytes (T cells) and
antigen-presenting cells (APCs).
Following exposure of these cell
types to an antigen, they retain the
ability to recognize the same antigen
in the future which leads to faster
immune system response time.
Innate vs. Adaptive Immune SystemThe immune system is comprised of two subdivisions—the innate immune system (non-specific)
and the adaptive immune system (specific).
Immunology
65
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
α-1-Acid Glycoprotein Chicken ELISA
41-AGPCH-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 15m
α-1-Acid Glycoprotein ELISA
41-AGPHU-E01 5–320 ng/mL 5 ng/mL 5 µL Plasma, Serum 1h 15m
α-1-Acid Glycoprotein Rat ELISA
41-AGPRT-E01 12.5–400 ng/mL 12.5 ng/mL 5 µL Plasma, Serum 1h 20m
α-1-Antitrypsin Canine ELISA
41-A1ACA-E01 12.5–800 ng/mL 12.5 ng/mL 5 µL Plasma, Serum 1h 15m
α-1-Antitrypsin Clearance ELISA
30-6752 3.3–90 µg/L 1.8 mg/dL 10 µL, 100 mg Plasma, Serum, Stool 2h 10m
α-1-Antitrypsin Mouse ELISA
41-A1AMS-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Serum 2h 5m
α-Fodrin Check IgG/IgA ELISA
35-AFCHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
AAI RIA 72-AAI See Protocol See Protocol 50 µL Plasma, Serum 2h 30m
ACE Kinetic High Sensitive Assay (CSF Samples)
01-KK-ACF 1–30 U/L 1 U/L 80 µL Cerebrospinal Fluid See Protocol
Active Dephosphorylated ß-Catenin ELISA
(S33/S37/T41)62-CATHU-E01 See Protocol See Protocol 100 µL
Cell Culture, Tissue Culture
4h 30m
AGP Canine ELISA 41-AGPCA-E016.17–1,500 ng/mL
6.17 ng/mL 5 µL Plasma, Serum 1h 40m
AKT1/2 (pS473/pS474) and GSK3α/ß (pS21/pS9) ELISA
62-AGGHU-E01 See Protocol See Protocol 100 µLCell Culture, Tissue Culture
4h 35m
AKT1/2 ELISA (pS473/pS474)
62-AKTHU-E01 See Protocol See Protocol 100 µLCell Culture, Tissue Culture
4h 30m
Alpha-Lactalbumin IgA ELISA
27-GD50Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Alpha-Lactalbumin IgG ELISA
27-GD51Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
ANA-8Pro ELISA 35-ANAHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h
ANA-8S IgG ELISA 35-AN8HU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h
Annexin V ELISA 61-ANNHU-E01 0.78–50 ng/mL 0.33 ng/mL 50 µL Cell Culture, Serum 3h 10m
Anti-ANCA IgG Screening ELISA
13-CP-111 * Cut-off: See Protocol
See Protocol 25 µL Serum 30m
Anti-Annexin V ELISA 61-AANHU-E01 6.3–400 ng/mL 1.2 ng/mL 50 µL Cell Culture, Serum 2h 10m
Anti-ASCA IgA ELISA 27-GD79Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-BPI IgA ELISA 27-GD11 See Protocol See Protocol 10 µL Plasma, Serum 1h 40m
Anti-BPI IgG ELISA 27-GD05 3.1–100 U/mL 3.1 U/mL 10 µL Plasma, Serum 1h 40m
Immunology
66
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Anti-C1q Autoantibodies ELISA
01-EK-AC1QA 5–400 U/mL 1 U/mL 10 µL Plasma, Serum 2h 15m
Anti-Cardiolipin IgA/IgG/IgM Screen ELISA
27-GD28 20–200 U/mL 1.9 U/mL 10 µL Plasma, Serum 1h 10m
Anti-Cardiolipin IgG ELISA 27-GD26 20–200 U/mL 0.63 U/mL 10 µL Plasma, Serum 1h 10m
Anti-Cardiolipin IgM ELISA 27-GD27 8–100 U/mL 0.2 U/mL 10 µL Plasma, Serum 1h 10m
Anti-Cardiolipin-A ELISA 35-CAAHU-E01 3–300 APL/mL 1 APl/mL 10 µL Serum 1h
Anti-Casein IgA ELISA 27-GD42Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-Casein IgG ELISA 27-GD43Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-CaSR lgG ELISA 43-CASHU-E01 10–270 U/mL 2.5 U/mL 10 µL Plasma, Serum 1h 50m
Anti-Cathepsin G ELISA 35-CATHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-CENP-B IgG ELISA 35-CENHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-Cytomegalovirus IgG ELISA
27-GD84Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum 50m
Anti-Cytomegalovirus IgM ELISA
27-GD85Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum 50m
Anti-ds-DNA ELISA 27-GD10 12–200 IU/mL 1 IU/mL 10 µL Plasma, Serum, Urine 1h
Anti-ds-DNA IgA/IgG/IgM Screen ELISA
35-DSSHU-E01 3–300 U/mL 1 U/mL 10 µL Plasma, Serum, Urine 1h
Anti-ds-DNA-A ELISA 35-DSAHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-ds-DNA-G ELISA 35-DSGHU-E01 3–300 IU/mL 1 IU/mL 10 µL Serum 1h
Anti-ds-DNA-M ELISA 35-DSMHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-Elastase ELISA 35-ELAHU-E01 3–300 U/mL 1 U/mL 100 µL Serum 1h
Anti-Epidermal Transglutaminase IgA ELISA
30-9396Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 2h 30m
Anti-GBM & ANCA Rapid Screen ELISA
13-GCP-100 * See Protocol See Protocol 25 µL Serum 30m
Anti-GBM IgG ELISA 13-GP-104x * 10–320 U/mL See Protocol 5 µL Serum 2h
Anti-Gliadin IgA ELISA 27-GD17 6.25–100 U/mL 0.25 U/mL 10 µL Serum 1h 10m
Anti-Gliadin IgA/IgG ELISA 27-GD77 6.25–100 U/mL 0.5 U/mL 10 µL Plasma, Serum 1h 10m
Anti-Gliadin IgG ELISA 27-GD16 6.25–100 U/mL 0.25 U/mL 10 µL Serum 1h 10m
Anti-HAV ELISA 22-E10 10–50 mIU/mL 0.1 IU/mL 10 µL Plasma, Serum 4h
67
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Anti-HAV IgG ELISA 68-4AGE3 See Protocol See Protocol 10 µLCitrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
1h 30m
Anti-HAV IgM ELISA 68-4AME3 See Protocol See Protocol 5 µLCitrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
2h
Anti-HBc IgG ELISA 68-4CBE3 See Protocol See Protocol 5 µLCitrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
1h 30m
Anti-HBc IgM ELISA 68-4CME3 See Protocol See Protocol 5 µLCitrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
2h 30m
Anti-HBs ELISA 68-4SBE3 See Protocol See Protocol 50 µLCitrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
1h 30m
Anti-HCV ELISA 68-4NAE3 See Protocol See Protocol 100 µL Plasma, Serum 1h 45m
Anti-Helicobacter Pylori IgA ELISA
27-GD08Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-Helicobacter Pylori IgG ELISA
27-GD01 6.25–100 U/mL 6.25 U/mL 10 µL Plasma, Serum 1h 10m
Anti-Helicobacter Pylori IgM ELISA
27-GD124Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum 1h 10m
Anti-Helicobacter Pylori Qualitative IgG ELISA
27-GD21Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 50m
Anti-Helicobactor Pylori ELISA
30-6920Cut-off: See Protocol
See Protocol 100 mg Stool 3h
Anti-Herpes-1/2 IgM ELISA 27-GD88Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum 50m
Anti-Histone C IgG ELISA 35-HSCHU-E01 3–300 U/mL 1 U/mL 10 µL Plasma, Serum 1h
Anti-Histone H1 IgG ELISA 35-HH1HU-E01 3–300 U/mL 1 U/mL 10 µL Plasma, Serum 1h 20m
Anti-Histone H2A IgG ELISA
35-H2AHU-E01 3–300 U/mL 1 U/mL 10 µL Plasma, Serum 1h
Anti-Histone H3 IgG ELISA 35-HH3HU-E01 3–300 U/mL 1 U/mL 10 µL Plasma, Serum 1h
Anti-Histone H4 IgG ELISA 35-HH4HU-E01 3–300 U/mL 1 U/mL 10 µL Plasma, Serum 1h
Anti-IFN ß Binding Antibodies ELISA
01-EK-IFNB20–500 titer units
See Protocol 20 µL Serum 4h 30m
Anti-Inositol-GM ELISA 35-INOHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-Insulin IgG ELISA 35-INAHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-Intrinsic Factor IgG ELISA
27-GD35Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-Intrinsic Factor IgG ELISA (Recombinant)
27-GD126Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Immunology
68
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Anti-Jo-1 DIASTAT® ELISA 13-FAJO200 * See Protocol See Protocol 100 µL Plasma, Serum 2h
Anti-Jo-1 ELISA 35-JO1HU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h 30m
Anti-LC1 IgG ELISA 35-LC1HU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h 30m
Anti-LKM-1 IgG ELISA 35-LKMHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h 5m
Anti-M2 IgG ELISA 35-M2GHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-MAG Autoantibodies ELISA
01-EK-MAG ^ 1,000–70,000 titer units
See Protocol 2 µL Serum 4h 30m
Anti-MPO ELISA 27-GD02 3.1–100 U/mL 3.1 u/mL 20 µL Serum 1h 10m
Anti-MPO-ANCA IgG Capture ELISA
13-CAP-MPO-110 * 10–320 U See Protocol 5 µL Serum 2h
Anti-Ovalbumin IgA ELISA 27-GD40Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-Ovalbumin IgG ELISA 27-GD41Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-Ovarian Antibody ELISA
20-OVAHU-E01 6–100 U/mL 6 U/mL 5 µL Serum 2h 30m
Anti-Phosphatidyl-Serine-IgG/IgM ELISA
35-SERHU-E01 3–300 U/mL 1 U/mL 10 µL Plasma, Serum 1h
Anti-Phospholipid-8 IgG/IgM ELISA
35-P8PHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h
Anti-Phospholipid-8Pro-A ELISA
35-8PAHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h
Anti-Phospholipid-8S-A ELISA
35-8SAHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h
Anti-PR3 ANCA ELISA 27-GD03 6.3–100 U/mL 0.5 U/mL 100 µL Plasma, Serum 1h
Anti-Prothrombin Factor II IgG ELISA
27-GD76 10–200 U/mL 10 U/mL 10 µL Plasma 1h 10m
Anti-Prothrombin IgA ELISA
35-PTAHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-Prothrombin IgM ELISA
35-PTMHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-RF IgA ELISA 27-GD24 25–400 U/mL 3 U/mL 10 µL Plasma, Serum 1h
Anti-RF IgG ELISA 27-GD37 40–400 U/mL 3 U/mL 10 µL Plasma, Serum 1h
Anti-RF IgM ELISA 27-GD23 25–400 U/mL 3 U/mL 10 µL Plasma, Serum 1h
Anti-RF Screen ELISA 27-GD06 25–500 U/mL 3 U/mL 10 µL Plasma, Serum 1h 10m
Anti-Ribosomal P IgG ELISA 35-RIBHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-Rubella IgG ELISA 27-GD82Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum 50m
69
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Anti-Scl 70 IgG ELISA 35-SCIHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-SGPG Autoantibodies ELISA
01-EK-SGPG ^ Cut-off: See Protocol
See Protocol 2 µL Serum 4h 30m
Anti-SLA IgG ELISA 35-SLAHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h 35m
Anti-Sm IgG ELISA 35-SMIHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-Sm/RNP-C IgG ELISA 35-SNRHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-Soya IgA ELISA 27-GD44Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-Soya IgG ELISA 27-GD45Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-Sperm Antibody ELISA 20-ASAHU-E01 62–500 U/mL 62 U/mL 10 µL Plasma, Serum 1h 30m
Anti-ß 2 Glycoprotein IgA ELISA
27-GD30 See Protocol See Protocol 10 µL Plasma, Serum 1h 10m
Anti-ß 2 Glycoprotein IgG ELISA
27-GD31 5–100 U/mL 5 U/mL 10 µL Plasma, Serum 1h 10m
Anti-ß 2 Glycoprotein IgM ELISA
27-GD32Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-ß 2 Glycoprotein Screen ELISA
35-B2SHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-ß Lactoglobulin IgA ELISA
27-GD38Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-ß Lactoglobulin IgG ELISA
27-GD39Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Anti-SS-A/Ro IgG ELISA 35-SSAHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-SS-A-52 IgG ELISA 35-S52HU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-SS-A-60 IgG ELISA 35-S60HU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-SS-B-La IgG ELISA 35-SSBHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-ss-DNA ELISA 27-GD12 50–400 U/mL 1.1 U/mL 10 µL Plasma, Serum 50m
Anti-ss-DNA IgA ELISA 35-SDAHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-ss-DNA IgA/IgG/IgM Screen ELISA
35-SSSHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-ss-DNA IgG ELISA 35-SDGHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-ss-DNA IgM ELISA 35-SDMHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Antithrombin IgA ELISA 35-TBAHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Antithrombin IgG/IgM ELISA
35-TBGHU-E01 3–300 U/mL 1 U/mL 100 µL Serum 1h
Immunology
70
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Anti-Tissue Transglutaminase IgA ELISA
27-GD70 5–100 U/mL 5 U/mL 10 µL Plasma, Serum 1h 10m
Anti-TNF α Inhibitor ELISA (Antibody
Against ENBREL®)30-9653
Cut-off: See Protocol
See Protocol 100 µL Serum Overnight
Anti-TNF α Inhibitor ELISA (Antibody Against Humira®)
30-9652Cut-off: See Protocol
See Protocol 100 µL EDTA Plasma, Serum Overnight
Anti-TNF α Inhibitor ELISA (Antibody
Against Remicade®)30-9650
Cut-off: See Protocol
See Protocol 100 µL Plasma, Serum Overnight
Anti-tTg-A ELISA 35-TGAHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h 30m
Anti-tTg-G ELISA 35-TGGHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-U1-70 ELISA 35-U17HU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-α Fodrin IgA ELISA 35-AFOHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Anti-α Fodrin IgG ELISA 35-AFGHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
APRIL ELISA 30-941115.6–1,000 ng/mL
15.6 ng/mL 100 µL Cell Culture, Plasma 6h 20m
APRIL ELISA 61-APRHU-E01 0.78–50 ng/mL 0.4 ng/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
ASCA IgG ELISA 27-GD78Cut-off: See Protocol
See Protocol 10 µL Plasma, Serum 1h 10m
Aspergillus IgG Antibody ELISA
27-GD29 12.5–100 U/mL 0.17 U/mL 100 µL Serum 1h 10m
BAFF ELISA 30-9410 2–128 ng/mL 0.95 ng/mL 50 µL Cell Culture, Serum 5h 50 m
Bcl-2 ELISA 61-BCLHU-E01 0.50–32 ng/mL 0.5 ng/mL 20 µLPlasma, Serum, Tissue Culture
3h 10m
Blastocystis Antigen ELISA 50-714-01Cut-off: See Protocol
See Protocol See Protocol Stool 2h 15m
Bordetella Pertussis IgG ELISA
20-BPGHU-E01 * See Protocol See Protocol 10 µL Serum 1h 45m
C. Trachomatis IFA 50-580-01 See Protocol See Protocol 10 µL Serum 1h
C4a RIA 51-RK-519 40–1,300 ng/mL 40 ng/mL 450 µL Plasma 1h
C5a ELISA 20-C5AHU-E01 0.1–10 µg/L 0.02 µg/L 50 µL Plasma 35m
Calprotectin CALcheck Blue™ Dipstick (25 tests)
01-DS-CAL25Cut-off: See Protocol
See Protocol See Protocol Stool 10m
Calprotectin ELISA 01-EK-CAL ^ † 10–600 µg/g or 30–1,800 µg/g
10 µg/g 50 mg Stool 1h 15m
71
* FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed † Pending FDA Clearance
Products are for Research Use Only unless otherwise noted
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Calprotectin ELISA (2x96 Wells)
01-EK-CAL-02 ^ 10–600 µg/g or 30–1,800 µg/g
10 µg/g 50 mg Stool 1h 15m
Calprotectin Quantum Blue® High Range
Rapid Test01-LF-CHR25 ^ 100–1,800 µg/g 100 µg/g 80 mg Stool 15m
Calprotectin Quantum Blue® Rapid Test
01-LF-CAL25 ^ 30–300 µg/g 10 µg/g 80 mg Stool 12m
Cancer Antigen 125 ELISA 25-125HU-E01 15–400 U/mL 15 U/mL 100 µL Serum 1h 50m
Cancer Antigen 15-3 ELISA 25-153HU-E01 15–240 U/mL 5 U/mL 20 µL Serum 3h 20m
Cancer Antigen 19-9 ELISA 25-199HU-E01 15–240 U/mL 5 U/mL 100 µL Serum 3h 20m
Cancer Antigen 50 RIA 72-OCFM7-CA50 0.4–180 U/mL 0.4 U/mL 50 µL Plasma, Serum 4h
CCPlus® ImmunoscanMeasurement of anti-cyclic citrullinated peptide (CCP)
antibodies has become the method of choice for accurate
diagnosis of rheumatoid arthritis (RA). A diagnostic value
for the measurement of anti-CCP antibodies has been
found in relation to joint involvement and radiological
damage on early RA. Anti-CCP antibodies have a high
positive predictive value and can be detected years before
the development of clinical symptoms.1-6
The FDA registered CCPlus® Immunoscan assay provides
sensitive and semi-quantitative determination of IgG
antibodies to CCP in human sera. The assay is used to
detect antibodies in a single serum specimen and is as
sensitive as the rheumatoid factor and CCP3 tests but with
higher clinical specificity.6
Total # Patients(RA/Controls)
StratifiedSpecificity (%)
CCPlus®
Immunoscan CCP3 MCV RF
100/102 98.5% 73 67 62 17
Sensitivity at stratified specificity (%) for available RA diagnostic markers6
Immunology
72
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Cancer Antigen 72-4 LIA 20-724HU-L01 0.14–100 U/mL 0.14 I/mL 10 µL Plasma, Serum 1h 30m
Cardiolipin IgG/IgM ELISA 35-CAGHU-E01 3–300 GPL/mL 1 GPl/mL 10 µL Serum 1h
Caspase-8 ELISA 61-CA8HU-E01 0.16–10 ng/mL 0.10 ng/mL 50 µLCell Culture, Serum, Tissue Culture
3h
Caspase-9 ELISA 61-CA9HU-E01 1.6–100 ng/mL 0.4 ng/mL 50 µLCell Culture, Serum, Tissue Culture
3h 10m
Cathepsin L ELISA 61-CALHU-E01 3.1–50 ng/mL 1.7 ng/mL 50 µL Cell Culture, Serum 3h 10m
CCPlus Immunoscan® (Anti-CCP ELISA)
13-RA-96PLUS * 25–3,200 U/mL See Protocol 10 µL Serum 2h
CD153 ELISA 61-153HU-E01 1.6–100 ng/mL 0.5 ng/mL 50 µL Cell Culture, Serum 3h 10m
CEA ELISA 25-CEAHU-E01 3–120 ng/mL 3 ng/mL 50 µL Serum 1h 20m
1 Rantapää-Dahlqvist S, de Jong BA, Berglin E, et al. Antibodies against cyclic
citrullinated peptide and IgA rheumatoid factor predict the development of
rheumatoid arthritis. Arthritis Rheum. Oct 2003; Vol 48 No 10: 2741-2749.
2 van Venrooij WJ, van Beers JJ, Pruijn GJ. Anti-CCP antibodies: the past, the
present and the future. Nat Rev Rheumatol. Jun 2011; Vol 7 No 7: 391-398
3 Svärd A, Kastbom A, Söderlin MK, et al. A comparison between IgG- and
IgA-class antibodies to cyclic citrullinated peptides and to modified
citrullinated vimentin in early rheumatoid arthritis and very early arthritis. J
Rheumatology. Jul 2011; Vol 38 No 7: 1265-1272.
4 Aletaha D, Neogi T, Silman AJ, Et al. 2010 Rheumatiod arthritis classification
criteria: a American College of Rheumatology/European League Against
Rheumatism collaborative initiative. Arthritis Rheum. Sep 2010; Vol 69 No
9: 1580-1588.
5 Pruijn GJ, Wiik A, van Venrooij WJ. The use of citrullinated peptides and
proteins for the diagnosis of rheumatoid arthritis. Arthritis Res Ther. 2010;
Vol 12 No 1: 203.
6 Bizzaro N, Tonutti E, Tozzoli R, Villalta D. Analytical and diagnostic
characteristics of 11 2nd- and 3rd- generation immunoenzymatic methods
for the detection of antibodies to citrullinated proteins. Clin Chem. Aug
2007; Vol 53 No 8: 1527-1533.
View CCPlus® Immunoscan assay 13-RA-96PLUS on page 73
73
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
CeliCheck ELISA (Tissue Transglutaminase
IgA/IgG ELISA)35-CELHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h 30m
Cell Proliferation & Toxicity Assay (EZ4U Assay)
04-BI-5000 See Protocol See Protocol 200 µL Cell Culture 2h
Chemerin ELISA 22-CHM-E102 25–600 pg/mL 0.005 pg/mL 10 µL Plasma, Serum 2h 30m
Chlamydia IgA IFA 50-513-01 See Protocol See Protocol 10 µL Serum 1h
Chlamydia IgG IFA 50-511-01 See Protocol See Protocol 10 µL Serum 1h
Chlamydia IgM IFA 50-512-01 See Protocol See Protocol 5 µL Serum 1h
Chymotrypsin ELISA 30-6910 20–1,000 ng/mL 20 ng/mL 100 mg Stool 2h 30m
CIC ELISA (C1q) 01-EK-CIC * 1–50 µg Eq/mL 0.6 µg Eq/mL 20 µL Serum 2h
CINC-1 Rat ELISA 48-CINRT-E01 12.5–800 pg/mL 12.5 pg/mL 25 µLEDTA Plasma, Heparin Plasma, Serum
2h 30m
Complement Factor 3 Canine ELISA
41-CO3CA-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h
Complement Factor 3 Guinea Pig ELISA
41-CO3GP-E013.125–200 ng/mL
3.125 ng/mL 5 µL Plasma, Serum 30m
Complement Factor 3 Mouse ELISA
41-CO3MS-E013.125–200 ng/mL
3.125 ng/mL 5 µL Plasma, Serum 50m
Complement Factor 3 Rat ELISA
41-CO3RT-E01 12.5–800 ng/mL 12.5 ng/mL 5 µL Plasma, Serum 50m
Complement Functional Screen Total ELISA
13-COMPL-300Cut-off: See Protocol
See Protocol 20 µL Serum 1h
Complement System Alternative Pathway ELISA
13-COMPL-AP330Cut-off: See Protocol
See Protocol 5 µL Serum 2h
C-Reactive ProteinCRP is released as a part of the acute-phase innate system
response which aims to neutralize the inflammatory agent
and to promote the healing of the injured tissue. During the
acute-phase response, CRP levels can increase by up to a
1000-fold and levels remain high as long as the damage
persists. Because the half-life of this marker is constant, CRP
levels can be used to study the severity of the precipitating
cause of inflammation. ALPCO has immunoassays available
for testing CRP levels in plasma and serum from canine,
equine, feline, human, mouse, porcine, rabbit and rat.
View CRP assays on page 75
Immunology
74
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Complement System Classical Pathway ELISA
13-COMPL-CP310Cut-off: See Protocol
See Protocol 5 µL Serum 2h
Complement System MBL Pathway ELISA
13-COMPL-MP320Cut-off: See Protocol
See Protocol 5 µL Serum 2h
CPA IgA ELISA 27-GD121 6.25–100 µmol/L 6.25 U/mL 10 µL Plasma, Serum 1h
CPA IgG ELISA 27-GD110 6.25–100 µmol/L 6.25 U/mL 10 µg Plasma, Serum 1h
CPA IgM ELISA 27-GD120 0–100 U/mL 6.25 U/mL 10 µL Plasma, Serum 1h
C-Reactive Protein Porcine ELISA
41-CRPPO-E01 6.25–200 ng/mL 5 ng/mL 5 µL Serum 25m
CREB ELISA (pS133) 62-CREHU-E01 See Protocol See Protocol 100 µLCell Culture, Tissue Culture
4h 30m
Cripto-1 ELISA 20-CRIHU-E01 50–800 pg/mL 8.4 pg/mL 50 µL Serum 3h 50m
Crohns Check ELISA (Anti-Saccharomyces
Cerevisiae IgA/IgG ELISA)35-CROHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
CRP Canine ELISA 41-CRPCA-E012.125–200 ng/mL
5 ng/mL 5 µL Plasma, Serum 25m
CRP ELISA 30-9710s 1.9–150 ng/mL 0.124 ng/mL 10 µLPlasma, Serum, Stool, Urine
2h 15m
CRP Equine ELISA 41-CRPEQ-E01 10–320 ng/mL 10 ng/mL 5 µL Plasma, Serum 1h 15m
CRP Feline ELISA 41-CRPFE-E013.125–200 ng/mL
3.125 ng/mL 5 µL Plasma, Serum 1h 15m
CRP Mouse ELISA 41-CRPMS-E01 0.39–25 ng/mL 0.39 ng/mL 5 µL Plasma, Serum 25m
CRP Rabbit ELISA 41-CRPRB-E01 6.25–200 ng/mL 5 ng/mL 2 µL Plasma, Serum 25m
CRP Rat ELISA 41-CRPRT-E01 6.25–200 ng/mL 5 ng/mL 5 µL Plasma, Serum 25m
CTGF ELISA 20-CTGHU-E01 1–500 ng/mL 3.24 ng/mL 25 µL Serum 3h 45m
Cu/ZnSOD ELISA 61-CUZHU-E01 0.08–5 ng/mL 0.04 ng/mL 10 µL
Amniotic Fluids, Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Urine
1h 10m
CYFRA LIA (21-1) 20-CYFHU-L01 3–50 ng/mL 0.03 ng/mL 50 µL Heparin Plasma, Serum 30m
Cytochrome C ELISA 61-CYCHU-E01 0.08–5 ng/mL 0.05 ng/mL 100 µL Tissue Culture 3h 10m
Dengue NS1 ELISA 65-DENHU-E01 See Protocol See Protocol 50 µL Serum 1h 51m
DIASTAT® ANA ELISA 13-FANA200 * See Protocol See Protocol 10 µL EDTA Plasma, Serum 2h
DIASTAT® MPO ANCA ELISA
13-FMPO200 * 0–100 U/mL See Protocol 100 µL Plasma, Serum 2h
75
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
EGF ELISA 45-EGFHU-E01 3.9–250 pg/mL 1 pg/mL 100 µLCell Culture, Citrate Plasma, Heparin Plasma, Serum, Urine
4h
EGF Receptor ELISA 30-7110 3–24 fmol/mL 0.4 fmol/mL 200 µL Tissue Culture Overnight
ENA-6Pro ELISA 35-E6PHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h
ENA-6S ELISA 35-E6SHU-E01 10–100 U/mL 1 U/mL 10 µL Serum 1h
Eotaxin Mouse ELISA 61-EOTMS-E0131.3–2,000 pg/mL
3.6 pg/mL 50 µL Cell Culture, Serum 3h 10m
ERK1/2 ELISA (pT202/Y204/pT185/Y187)
62-ERKHU-E01 See Protocol See Protocol 100 µLCell Culture, Tissue Culture
4h 35m
FGF-21 ELISA 62-FGFHU-E01 30–1,920 pg/mL 10.4 pg/mL 100 µLCell Culture, Plasma, Serum
2h 35m
FGF-21 Mouse ELISA 62-FGFMS-E0131.2–2,000 pg/mL
10.1 pg/mL 100 µLCell Culture, Plasma, Serum
2h 35m
GAD ELISA 21-GADHU-E01 0.6–2.99 U/mL See Protocol 10 µL Serum 2h 30m
Galectin-3 ELISA 61-GALHU-E01 0.39–25 ng/mL 0.12 ng/mL 50 µLCell Culture, EDTA Plasma, Serum
3h 10m
GanglioCombi® Anti-Ganglioside Auto
Antibody ELISA01-EK-GCO
Cut-off: See Protocol
See Protocol 30 µL Serum 4h 30m
GanglioCombi® Light Anti-Ganglioside ELISA
01-EK-GCL-GMCut-off: See Protocol
See Protocol 30 µL Serum 4h 30m
G-CSF ELISA 45-GCSHU-E01 39–2,500 pg/mL 20 pg/mL 50 µLCell Culture, EDTA Plasma, Serum
3h
GM-CSF ELISA 61-GMCHU-E01 7.8–500 pg/mL 2.9 pg/mL 50 µLCell Culture, EDTA Plasma, Heparin Plasma, Serum
3h 10m
GM-CSF Mouse ELISA 61-GMCMS-E01 3.9–250 pg/mL 2 pg/mL 50 µL Cell Culture, Serum 3h
GM-CSF Rat ELISA 61-GMCRT-E01 7.8–500 pg/mL 3.5 pg/mL 50 µL Cell Culture, Serum 3h 10m
Granzyme A ELISA 61-GRAHU-E01 0.8–600 pg/mL 0.4 pg/mL 50 µLCell Culture, Plasma, Serum
2h
Granzyme B ELISA 61-GRBHU-E01 0.66–480 pg/mL 0.2 pg/mL 50 µL Cell Culture, Serum 2h
GSK3α/ß (pS21/pS9) and Active ß-Catenin ELISA
62-GCAHU-E01 See Protocol See Protocol 100 µLCell Culture, Tissue Culture
4h 30m
GSK3α/ß ELISA (pS21/pS9) 62-GSKHU-E01 See Protocol See Protocol 100 µLCell Culture, Tissue Culture
4h 30m
HAHA ELISA 43-HAHHU-E01 1–27 µg/mL 1 µg/mL 25 µL Plasma, Serum 1h 50m
HAMA ELISA 43-HAMHU-E01 40–1,500 ng/mL 2 ng/mL 25 µL Serum 1h 50m
Haptoglobin Bovine ELISA 41-HAPBO-E0115.6–1,000 ng/mL
15.6 ng/mL 5 µL Plasma, Serum 40m
Immunology
76
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Haptoglobin Canine ELISA 41-HAPCA-E01 7.81–125 ng/mL 5 ng/mL 5 µL Plasma, Serum 40m
Haptoglobin ELISA 41-HAPHU-E013.125–200 ng/mL
3.125 ng/mL 100 µL Plasma, Serum 35m
Haptoglobin Equine ELISA 41-HAPEQ-E0118.75–600 ng/mL
18.75 ng/mL 5 µL Plasma, Serum 1h 15m
Haptoglobin Feline ELISA 41-HAPFE-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 15m
Haptoglobin Mouse ELISA 41-HAPMS-E01 7.81–125 ng/mL 5 ng/mL 5 µL Plasma, Serum 35m
Haptoglobin Porcine ELISA 41-HAPPO-E01 25–400 ng/mL 5 ng/mL 5 µL Plasma, Serum 40m
Haptoglobin Rabbit ELISA 41-HAPRB-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 30m
Haptoglobin Rat ELISA 41-HAPRT-E01 7.81–125 ng/mL 5 ng/mL 5 µL Plasma, Serum 35m
HBe/Anti-HBe ELISA 68-4BNE3 See Protocol See Protocol 50 µL Plasma, Serum 2h 30m
HBsAg ELISA 68-4SGE3 See Protocol See Protocol 50 µLCitrate Plasma, EDTA Plasma, Heparin Plasma, Plasma, Serum
1h 50m
hCOMP ELISA 13-COMP-200 10–80 ng/mL 10 ng/mL 5 µL Serum Overnight
HER-2 ELISA 61-HERHU-E01 0.16–10 ng/mL 0.06 ng/mL 100 µLAmniotic Fluids, Cell Culture, EDTA Plasma, Heparin Plasma, Serum
2h 10m
Herpes Simplex Virus 1 IgM ELISA
20-HSMHU-E01 See Protocol See Protocol 10 µL Serum 1h 45m
Histamine ELISA 17-HISHU-E01 0.3–30 ng/mL See Protocol 25 µL Plasma, Urine Overnight
Histamine ELISA (Cell Culture)
17-HISCC-E01 0.5–50 ng/mL 0.2 ng/mL 20 µL Cell Culture, Urine 1h
Histamine Research ELISA 17-HISRT-E01-RES 0.3–30 ng/mL 0.2 ng/mL 10 µL EDTA Plasma Overnight
IFN-gamma ELISA 61-IFGHU-E01 1.6–100 pg/mL 0.99 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
IFN-gamma Monkey ELISA 45-IFNMK-E0115.6–1,000 pg/mL
4 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
4h
IFN-gamma Mouse ELISA 61-IFGMS-E0115.6–1,000 pg/mL
5.3 pg/mL 50 µL Cell Culture, Serum 3h 10m
IFN-gamma Rat ELISA 61-IFGRT-E0131.3–2,000 pg/mL
9.9 pg/mL 50 µL Cell Culture, Serum 3h 10m
IgA Chicken ELISA 41-IGACH-E01 12.5–400 ng/mL 12.5 ng/mL 100 µL Plasma, Serum 50m
IgA ELISA 41-IGAHU-E01 12.5–800 ng/mL 12.5 ng/mL 5 µL Plasma, Serum 1h 10m
IgA Mouse ELISA 41-IGAMS-E0112.5–3,025 ng/mL
12.5 ng/mL 5 µL Plasma, Serum 1h 40m
77
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
IgA Rat ELISA 41-IGART-E0131.25–1,000 pg/mL
31.25 ng/mL 5 µL Plasma, Serum 1h 10m
IgD ELISA 41-IGDHU-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 30m
IgE Canine ELISA 41-IGECA-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 15m
IgE Equine ELISA 41-IGEEQ-E013.125–100 ng/mL
3.125 ng/mL 5 µL Plasma, Serum 1h 45m
IgE Feline ELISA 41-IGEFE-E01 12.5–400 ng/mL 12.5 ng/mL 10 µL Plasma, Serum 2h 15m
IgE Mouse ELISA 41-IGEMS-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 15m
IgE Rat ELISA 41-IGERT-E01 1–32 ng/mL 1 ng/mL 10 µL Plasma, Serum 2h 15m
IgE Total ELISA 25-IGEHU-E01 * 10–800 IU/mL 5 IU/mL 20 µL Serum 1h 20m
IgG Canine ELISA 41-IGGCA-E01 25–800 ng/mL 25 ng/mL 5 µL Plasma, Serum 45m
IgG Mouse ELISA 41-IGGMS-E019.375–600 ng/mL
9.375 ng/mL 5 µL Plasma, Serum 1h 45m
IgG Rat ELISA 41-IGGRT-E01 25–800 ng/mL 25 ng/mL 5 µL Plasma, Serum 1h 45m
IgG Total ELISA 30-6510 0.32–5 mg/L 0.14 mg/L 10 µLCell Culture, Plasma, Serum
2h 5m
IgG1 Mouse ELISA 41-IG1MS-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 30m
IgG2A Mouse ELISA 41-I2AMS-E01 12.5–400 ng/mL 12.5 ng/mL 5 µL Plasma, Serum 1h 30m
IgG2B Mouse ELISA 41-I2BMS-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 15m
IgG3 Mouse ELISA 41-IG3MS-E01 12.5–400 ng/mL 12.5 ng/mL 5 µL Plasma, Serum 1h 30m
IgM Canine ELISA 41-IGMCA-E01 25–800 ng/mL 25 ng/mL 5 µL Plasma, Serum 1h 15m
IgM Chicken ELISA 41-IGMCH-E013.125–200 ng/mL
3.125 ng/mL 5 µL Plasma, Serum 1h 15m
IgM ELISA 41-IGMHU-E01 7.8–500 ng/mL 7.8 ng/mL 5 µL Plasma, Serum 1h 45m
IgM Mouse ELISA 41-IGMMS-E01 25–800 ng/mL 25 ng/mL 5 µL Plasma, Serum 1h 45m
IgM Rat ELISA 41-IGMRT-E0131.25–1,000 ng/mL
31.25 ng/mL 5 µL Plasma, Serum 1h 15m
IgY Chicken ELISA 41-IGYCH-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 15m
IL-10 ELISA 61-I10HU-E01 3.15–200 pg/mL 1 pg/mL 50 µLCell Culture, Citrate Plasma, Heparin Plasma, Serum
3h 10m
IL-10 Monkey ELISA 61-I10MK-E01 3.9–250 U/mL 1.3 U/mL 50 µL Cell Culture, Serum 3h 10m
IL-10 Mouse ELISA 61-I10MS-E0115.6–1,000 pg/mL
5 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
4h 10m
Immunology
78
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
IL-10 Porcine ELISA 45-I10PO-E01 7.8–500 pg/mL 3 pg/mL 50 µLCell Culture, Plasma, Serum
3h
IL-10 Rat ELISA 61-I10RT-E0115.6–1,000 pg/mL
1.5 pg/mL 50 µL Cell Culture, Serum 3h 10m
IL-10 Ultrasensitive ELISA 45-I10HUU-E01 0.78–50 pg/mL 0.2 pg/mL 100 µLCell Culture, Plasma, Serum
4h
IL-10 Ultrasensitive ELISA 45-I10HUU-E05 0.78–50 pg/mL 0.2 pg/mL 100 µLCell Culture, Plasma, Serum
4h
IL-12 ELISA (p70) 61-P12HU-E01 3.1–200 pg/mL 2.1 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
IL-12 Monkey ELISA (p70) 61-P12MK-E01 3.9–250 U/mL 2.6 U/mL 50 µL Cell Culture, Serum 3h 10m
IL-12 Mouse ELISA (p70) 61-P12MS-E0115.6–1,000 pg/mL
10 pg/mL 50 µL Cell Culture, Serum 3h 10m
IL-12/IL-23 ELISA (p40) 61-ILPHU-E0131.3–2,000 pg/mL
< 10 pg/mL 50 µLCell Culture, Citrate Plasma, Heparin Plasma, Serum
4h 10m
IL-13 ELISA 61-I13HU-E01 1.6–100 pg/mL 0.7 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
2h 10m
IL-13 Mouse ELISA 61-I13MS-E01 7.8–500 pg/mL 2.8 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
3h 10m
IL-15/IL-15R Mouse ELISA 61-I15MS-E01 6.3–400 pg/mL 2 pg/mL 50 µLCell Culture, EDTA Plasma, Serum
3h 30m
IL-17A ELISA 61-ILAHU-E01 1.6–100 pg/mL 0.5 pg/mL 50 µLCell Culture, Citrate Plasma, Heparin Plasma, Serum
3h 10m
IL-17A Mouse ELISA 61-ILAMS-E01 7.8–500 pg/mL 1.6 pg/mL 50 µL Cell Culture, Serum 3h 10m
IL-17A Rat ELISA 61-ILART-E01 1.6–100 pg/mL 1 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 30m
IL-17AF ELISA 61-IAFHU-E0131.3–2,000 pg/mL
8.8 pg/mL 50 µLCell Culture, Citrate Plasma, Heparin Plasma, Serum
3h 30m
IL-17AF Mouse ELISA 61-IAFMS-E01 3.9–250 pg/mL 3.3 pg/mL 50 µLCell Culture, EDTA Plasma, Serum
3h 30m
IL-17F ELISA 61-ILFHU-E0131.3–2,000 pg/mL
15.5 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 30m
IL-17F Mouse ELISA 61-ILFMS-E0162.5–4,000 pg/mL
10 pg/mL 50 µLCell Culture, EDTA Plasma, Serum
4h 30m
IL-18 Porcine ELISA 61-I18PO-E0139.1–2,500 pg/mL
23 pg/mL 50 µL Cell Culture, Serum 3h 10m
79
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
IL-1RA ELISA 61-1RAHU-E01109–7,000 pg/mL
30 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 30m
IL-1ß Rat ELISA 61-I1BRT-E0131.3–2,000 pg/mL
4 pg/mL 50 µL Cell Culture, Serum 3h 10m
IL-1α ELISA 61-I1AHU-E01 1.6–100 pg/mL 1.1 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
IL-1α Mouse ELISA 61-I1AMS-E01 7.8–500 pg/mL 4 pg/mL 50 µL Cell Culture, Serum 3h 10m
IL-1α Rat ELISA 61-I1ART-E0115.6–1,000 pg/mL
4 pg/mL 50 µL Cell Culture, Serum 3h 10m
IL-2 ELISA 61-IL2HU-E0118.8–1,200 pg/mL
9.9 pg/mL 100 µL
Amniotic Fluids, Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Urine
3h 10m
IL-2 Monkey ELISA 61-IL2MK-E01 20–1,250 U/mL 10 U/mL 100 µL Cell Culture, Serum 3h 10m
IL-2 Mouse ELISA 61-IL2MS-E0115.6–1,000 pg/mL
5.3 pg/mL 50 µL Cell Culture, Serum 3h 10m
IL-2 Rat ELISA 61-IL2RT-E0162.5–2,000 pg/mL
11 pg/mL 50 µL Cell Culture, Serum 4h 10m
IL-21 ELISA 61-I21HU-E01 78–5,000 pg/mL 20 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
4h 10m
IL-22 ELISA 61-I22HU-E0131.3–2,000 pg/mL
5 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
4h 10m
IL-22 Mouse ELISA 61-I22MS-E01 7.8–500 pg/mL 5 pg/mL 50 µLCell Culture, Citrate Plasma, Serum
3h 30m
IL-23 ELISA 61-I23HU-E0115.6–2,000 pg/mL
4 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
3h
IL-23 Mouse ELISA 61-I23MS-E0131.3–2,000 pg/mL
16 pg/mL 50 µLCell Culture, Citrate Plasma, Serum
4h 10m
IL-27 ELISA 61-I27HU-E0162.5–4,000 pg/mL
9.5 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
3h 30m
IL-29 ELISA (IFN-lambda1) 61-IFLHU-E0115.6–1,000 pg/mL
2 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 30m
IL-3 ELISA 45-IL3HU-E01 7.8–500 pg/mL 1 pg/mL 100 µLCell Culture, Citrate Plasma, EDTA Plasma, Plasma, Serum
4h
IL-31 ELISA 61-I31HU-E01 7.8–500 pg/mL 1 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
4h 30m
Immunology
80
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
IL-33 ELISA 61-I33HU-E01 7.8–500 pg/mL 0.2 pg/mL 50 µLCell Culture, Citrate Plasma, Heparin Plasma, Serum
4h 30m
IL-4 ELISA 61-IL4HU-E01 7.8–500 pg/mL 1.3 pg/mL 50 µLCell Culture, Plasma, Serum
3h 10m
IL-4 Mouse ELISA 61-IL4MS-E01 3.9–250 pg/mL 2 pg/mL 50 µL Cell Culture, Serum 3h 10m
IL-4 Porcine ELISA 45-IL4PO-E0115.6–1,000 pg/mL
2 pg/mL 50 µL Cell Culture, Serum 3h
IL-4 Rat ELISA 45-IL4RT-E01 7.8–500 pg/mL 2 pg/mL 100 µL Cell Culture, Serum 3h
IL-4 Rat ELISA 61-IL4RT-E01 1.6–100 pg/mL 0.2 pg/mL 50 µL Cell Culture, Serum 3h 10m
IL-5 ELISA 61-IL5HU-E01 7.8–500 pg/mL 1.5 pg/mL 50 µL Cell Culture, Serum 3h 10m
IL-5 Mouse ELISA 61-IL5MS-E01 7.8–500 pg/mL 3.3 pg/mL 50 µL Cell Culture, Serum 3h 10m
IL-6 ELISA 45-IL6HU-E01 7.8–500 pg/mL 2 pg/mL 100 µLCell Culture, EDTA Plasma, Serum
3h
IL-6 ELISA 45-IL6HU-E05 7.8–500 pg/mL 2 pg/mL 100 µLCell Culture, EDTA Plasma, Serum
3h
IL-6 Monkey ELISA 61-IL6MK-E01 1.9–120 U/mL 1.3 U/mL 50 µL Cell Culture, Serum 3h 10m
IL-6 Mouse ELISA 61-IL6MS-E0131.3–2,000 pg/mL
6.5 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
3h 30m
IL-6 Rat ELISA 61-IL6RT-E01 31–2,000 pg/mL 12 pg/mL 50 µL Cell Culture, Serum 3h 10m
IL-8 ELISA 61-IL8HU-E0115.6–1,000 pg/mL
2 pg/mL 50 µLCell Culture, EDTA Plasma, Heparin Plasma, Serum
3h 10m
IL-8 Monkey ELISA 61-IL8MK-E01 19.5–1,250 U/mL 3 U/mL 50 µL Cell Culture, Serum 3h 10m
IL-8 Porcine ELISA 45-IL8PO-E0131.2–2,000 pg/mL
10 pg/mL 50 µL Cell Culture, Serum 4h
IL-8 Ultrasensitive ELISA 45-IL8HUU-E01 0.39–25 pg/mL 0.1 pg/mL 100 µLCell Culture, Plasma, Serum, Urine
4h
IL-9 ELISA 61-IL9HU-E01 3.1–200 pg/mL 0.5 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 30m
Insulin Autoantibody ELISA 21-IAAHU-E01Cut-off: See Protocol
See Protocol 25 µL Serum Overnight
IP-10 Mouse ELISA 61-IP1MS-E01 7.8–500 pg/mL 6.5 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
3h 10m
Islet Cell Antibody ELISA 21-ICAHU-E01Cut-off: See Protocol
See Protocol 25 µL Serum 2h 30m
Japanese Encephalitis IgG ELISA
65-JEGHU-E01 See Protocol See Protocol 4 µL Serum 2h 16m
81
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Japanese Encephalitis IgM ELISA
65-JEMHU-E01 See Protocol See Protocol 4 µL Serum 3h 16m
Kappa ELISA 41-KAPHU-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h
L1-CAM ELISA 20-LCAHU-E01 8.75–280 ng/mL 0.1 ng/mL 50 µL Serum 1h 45m
Lactoferrin ELISA 41-LACHU-E013.125–100 ng/mL
3.125 ng/mL 5 µL Milk, Plasma, Serum 1h 15m
Lambda ELISA 41-LAMHU-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h
L-Citrulline ELISA 30-6600 6.25–400 µM 6.25 µM 500 µL Plasma, Serum, Urine 1h 30m
Leukemia Inhbitory Factor ELISA
61-LIFHU-E01 3.15–200 pg/mL 0.7 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h
MCP-1 ELISA 61-MCPHU-E0115.6–1,000 pg/mL
2.3 pg/mL 20 µLCell Culture, EDTA Plasma, Heparin Plasma, Serum
2h 10m
MCP-1 Mouse ELISA 61-MCPMS-E0115.6–1,000 pg/mL
2.2 pg/mL 50 µL Cell Culture, Serum 3h 10m
MCP-1 Rat ELISA 45-MCPRT-E01 11.7–750 pg/mL 8 pg/mL 50 µLCell Culture, Plasma, Serum
2h 30m
Measles IgG ELISA 20-MEGHU-E01 * See Protocol See Protocol 10 µL Serum 1h 45m
MMP-13 ELISA 61-M13HU-E01 0.31–20 ng/mL 0.18 ng/mL 50 µL Cell Culture, Serum 3h 10m
MMP-3 ELISA 48-MP3HU-E01 12.5–800 ng/mL 0.01 ng/mL 40 µL Serum 2h
MMP-9 ELISA 61-MP9HU-E01 0.23–15 ng/mL 0.05 ng/mL 10 µLCell Culture, Citrate Plasma, Heparin Plasma, Serum
3h 10m
MPO ELISA 30-6630 1.2–100 ng/mL 1.6 ng/mL 100 mg Stool, Urine 2h 20m
MPO ELISA (Serum and Plasma)
30-6631A 1.9–30 ng/mL 1.08 ng/mL 10 µL Plasma, Serum 3h 20m
MPO Mouse ELISA 41-MPOMS-E01 0.31–20 ng/mL 0.31 ng/mL 5 µL Plasma, Serum 1h 30m
MRP 8/14 ELISA 01-EK-MRP8/14 0.4–24 µg/mL 0.4 µg/mL 10 µL Plasma, Serum 1h 15m
Mycobacterium Tuberculosis IgG ELISA
65-TBGHU-E01 See Protocol See Protocol 4 µL Serum 1h 16m
Mycobacterium Tuberculosis IgM ELISA
65-TBMHU-E01 See Protocol See Protocol 4 µL Serum 1h 16m
Neopterin ELISA 14-HD-99.1 2–250 nmol/L 2 nmol/L 50 µL Plasma, Serum, Urine 2h 30m
Neopterin RIA 14-HD-97.1 3–729 nmol/L 0.8 nmol/L 20 µL Biological Fluids 1h
NGAL Canine ELISA 54-043 4–400 pg/mL 0.56 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
Immunology
82
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
NGAL Canine ELISA 54-043 4–400 pg/mL 0.56 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL ELISA 54-036 10–1,000 pg/mL 4 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Mouse ELISA 54-042 10–500 pg/mL 0.75 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Porcine ELISA 54-044 10–400 pg/mL 1 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Rapid ELISA 54-037 0.2–20 ng/mL 0.008 ng/mL 10 µLEDTA Plasma, Plasma, Serum, Urine
1h
NGAL Rat ELISA 54-046 4–400 pg/mL 0.5 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
Nucleo-h IgG ELISA 35-NUCHU-E01 3–300 U/mL 1 U/mL 10 µL Serum 1h
Orientia Tsutsugamushi IgG ELISA
65-OTGHU-E01 See Protocol See Protocol 4 µL Serum 1h 16m
Orientia Tsutsugamushi IgM ELISA
65-OTMHU-E01 See Protocol See Protocol 4 µL Serum 1h 16m
NeopterinNeopterin serves as a marker of activation of the adaptive
immune system. It is synthesized by macrophages
upon stimulation with the cytokine interferon-gamma
and is indicative of a pro-inflammatory immune status.
Measurement of circulating neopterin concentrations
provides information about cellular immune activation in
humans under the control of T helper cells type 1. ALPCO
offers both an ELISA and an RIA for the measurement of
Neopterin in plasma, serum and urine.Neopterin [nmol/l]
Op
tica
l Den
sity
(OD
)
2
0.0
0.2
0.4
0.6
0.8
1.0
1.2
1.4
1.6
1.8
20 200
Representative Standard Curve from 14-HD-99.1
View neopterin assays 14-HD-99.1 and 14-HD-97.1 on page 82
83
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Immunology
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Osteopontin ELISA 41-OPNHU-E01 0.31–20 ng/mL 0.05 ng/mL 10 µL Heparin Plasma, Urine 3h
Ovotransferrin Chicken ELISA
41-OVOCH-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h
p38 α ELISA (pT180/Y182) 62-P38HU-E01 See Protocol See Protocol 100 µLCell Culture, Tissue Culture
4h 30m
p53 ELISA 61-P53HU-E01 0.78–50 U/mL 0.33 U/mL 50 µL Cell Culture, Serum 3h 10m
PAI-1 ELISA 61-PAIHU-E01 78–5,000 pg/mL 29 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
PAP Complex ELISA 20-PCOHU-E02 50–5,000 µg/L 10 µg/L 50 µL Plasma 45m
PAPP-A ELISA 20-PAPHU-E01 1–30 µg/mL 0.133 µg/mL 10 µL Plasma, Serum 1h 15m
PAPP-A Ultrasensitive ELISA
55-PAPHUU-E0111.25–450 ng/mL
0.023 ng/mL 100 µL Serum 45m
Pertussis IgG ELISA 13-PERT-PTG2 * Cut-off: See Protocol
See Protocol See Protocol Serum 2h
Platelet Derived Growth Factor ELISA
61-PDGHU-E0131.3–2,000 pg/mL
4.6 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 30m
PMN Elastase Ultrasensitive ELISA
30-6840 0.37–10 ng/mL 0.12 ng/mL 100 mg, 100 µLPlasma, Seminal Fluids, Serum, Stool
3h 15m
PMN-Elastase ELISA 61-PMNHU-E01 0.16–10 ng/mL 1.98 ng/mL 100 µLCell Culture, Plasma, Serum
2h
Porphyrins HPLC 30-2601 See Protocol See Protocol 1 mL Urine See Protocol
PR3-ANCA Capture ELISA 13-CAP-PR3 * Cut-off: See Protocol
See Protocol 10 µL Serum 2h
Progranulin ELISA 22-PRG-E103 0.75–25 ng/mL 0.018 ng/mL 10 µL Plasma, Serum 2h
PSA NCAM ELISA 67-ABC0027B 0.25–16 ng/mL 0.25 ng/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture
Overnight
PSA Total ELISA 25-PSAHU-E01 2–120 ng/mL 1 ng/mL 50 µL Serum 2h 20m
PSA Total LIA 11-PSAHU-L01 0.1–100 ng/mL 0.082 ng/mL 50 µL Serum 1h 30m
RANTES/CCL5 ELISA 45-RANHU-E0131.2–2,000 pg/mL
3 pg/mL 50 µL Cell Culture, Serum 2h
RC4d Antibody 04-BI-RC4D See Protocol See Protocol See Protocol See Protocol See Protocol
s90K/Mac-2BP ELISA 61-MACHU-E01 12.5–200 ng/mL 0.92 ng/mL 100 µLCell Culture, Plasma, Serum
1h
sAPO-1/Fas ELISA 61-APOHU-E0115.6–1,000 pg/mL
13.2 pg/mL 10 µL Cell Culture, Serum 2h 10m
sCD134 ELISA (OX40) 61-134HU-E01 78–5,000 pg/mL 1.8 pg/mL 25 µL Cell Culture, Serum 3h 10m
sCD137 ELISA 61-137HU-E01 0.78–50 ng/mL 0.2 ng/mL 50 µL Cell Culture, Serum 3h 10m
Immunology
84
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
sCD152/CTLA-4 ELISA 61-CTLHU-E01 0.16–10 ng/mL 0.13 ng/mL 10 µLCell Culture, EDTA Plasma, Heparin Plasma, Serum
3h 10m
sCD23 ELISA 61-C23HU-E01 12.5–400 U/mL 6.8 U/mL 100 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
sCD26 ELISA 61-C26HU-E01 15.6–500 ng/mL 7.3 ng/mL 20 µL Cell Culture, Serum 4h 10m
sCD28 ELISA 61-C28HU-E01 0.78–50 ng/mL 0.18 ng/mL 50 µL Cell Culture, Serum 3h 10m
sCD30 ELISA 61-C30HU-E01 1.6–100 ng/mL 0.3 ng/mL 25 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
sCD40 ELISA 61-C40HU-E01 7.8–500 pg/mL 1.3 pg/mL 50 µLAmniotic Fluids, Cell Culture, EDTA Plasma, Heparin Plasma, Serum
3h 10m
sCD40L ELISA 61-40LHU-E01 0.16–10 ng/mL 0.06 ng/mL 20 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
2h 10m
sCD40L Mouse ELISA 61-40LMS-E01 0.31–20 ng/mL 0.14 ng/mL 50 µL Cell Culture, Serum 3h 10m
RC4dWithin the adaptive system’s cascade of events is the classical complement
pathway, consisting of a number of small proteins in the blood including,
but not limited to C1, C2, C3 and C4. Until recently, it was thought that
the humoral pathway was most often associated with an acute transplant
rejection. However, there are visible features of humoral rejection seen in
more chronic rejection settings, especially in patients with renal allografts,
one of which is the deposition of C4d in the capillary bed of renal allografts.
C4d is a split product of C4. Because C4d covalently binds to adjacent
membrane surfaces it can be easily detected using conventional methods. As such, immunostaining with an antibody
targeting C4d is an important method that can be used to identify humoral-graft rejection.1
1 Troxwell, ML et al. Comparison of C4d immunostaining methods in renal allograft biopsies. Clinical J American Society Nephrology. May 2006; Vol 1 No 3: 583-591.
View RC4d assay 04-BI-RC4D on page 84
Paraffin embedded tissue sections
85
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
sCD44std ELISA 61-C44HU-E01 0.13–4 ng/mL 0.02 ng/mL 20 µL
Amniotic Fluids, Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Urine
3h 10m
sCD44var ELISA (v5) 61-445HU-E01 0.31–10 ng/mL 0.14 ng/mL 20 µL
Amniotic Fluids, Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Urine
3h 10m
sCD44var ELISA (v6) 61-446HU-E01 0.32–10 ng/mL 0.05 ng/mL 20 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
sCD-8 ELISA 61-CD8HU-E01 31–2,000 U/mL 7 U/mL 50 µL Citrate Plasma, Serum 3h 10m
Sclero-Profile IgG ELISA 35-SCLHU-E01Cut-off: See Protocol
See Protocol 10 µL Serum 1h
Secretory IgA ELISA 30-8870 22.2–600 ng/mL 13.4 ng/mL 100 mg, 10 µL Saliva, Stool 2h 10m
Secretory IgA1 ELISA 30-6863 3.3–100 U 3.3 U 100 mg Stool 2h 15m
Secretory IgA2 ELISA 30-6864 3.3–100 U 3.3 U 100 mg Stool 2h 15m
SeroMP lgG ELISA 50-FA261-01M 10–100 BU/mL See Protocol 10 µL Serum 2h 15m
SeroMP lgG ELISA (2 Plate) 50-B261-01M 10–100 BU/mL See Protocol 10 µL Serum 2h 15m
SeroMP lgM ELISA 50-FA262-01M 10–100 BU/mL See Protocol 10 µL Serum 2h 15m
SeroMP lgM ELISA (2 Plate) 50-B262-01M 10–100 BU/mL See Protocol 10 µL Serum 2h 15m
Serum Amyloid A ELISA 41-SAAHU-E01 0.157–10 ng/mL 0.157 ng/mL 10 µL Plasma, Serum 1h
Serum Amyloid A Mouse ELISA
41-SAAMS-E0131.25–2,000 ng/mL
31.25 ng/mL 5 µL Serum 1h 40m
Serum Amyloid ß Auto-Antibody ELISA
20-SABHU-E01 1–120 RTU See Protocol 20 µL Serum 2h 30m
sE-selectin ELISA 61-ESEHU-E01 0.8–50 ng/mL 0.3 ng/mL 20 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
2h 10m
sE-selectin Monkey ELISA 61-ESEMK-E01 1.9–60 U/mL 0.4 U/mL 20 µL Cell Culture, Serum 2h 10m
sFas Ligand ELISA 61-FALHU-E01 0.16–10 ng/mL 0.07 ng/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
sICAM-1 ELISA 61-IC1HU-E01 6.25–100 ng/mL 2.2 ng/mL 10 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
1h 10m
sICAM-1 Monkey ELISA 61-IC1MK-E01 6.3–100 U/mL 1.1 U/mL 10 µL Cell Culture, Serum 1h 10m
Immunology
86
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
sICAM-1 Ultrasensitive ELISA
61-IC1HUU-E01 0.63–10 ng/mL 0.33 ng/mL 100 µL
Amniotic Fluids, Cell Culture, EDTA Plasma, Heparin Plasma, Plasma, Serum, Urine
2h 10m
sICAM-2 ELISA 61-IC2HU-E01 0.75–24 U/mL 0.30 U/mL 100 µL
Amniotic Fluids, Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Urine, Whole Blood
1h
sICAM-3 ELISA 61-IC3HU-E01 0.78–50 ng/mL 0.38 ng/mL 20 µL
Amniotic Fluids, Cell Culture, EDTA Plasma, Heparin Plasma, Serum, Urine
2h 10m
sIL-2R ELISA 61-I2RHU-E01 0.31–20 ng/mL 0.27 ng/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 10m
sIL-6R ELISA 61-I6RHU-E01 0.08–5 ng/mL 0.01 ng/mL 20 µL
Amniotic Fluids, Cell Culture, EDTA Plasma, Heparin Plasma, Serum, Urine
2h 10m
sL-selectin ELISA 61-LSEHU-E01 0.4–25 ng/mL 0.2 ng/mL 50 µLCell Culture, EDTA Plasma, Heparin Plasma, Serum
2h 10m
sPECAM-1 ELISA 61-PECHU-E01 0.47–30 ng/mL 0.06 ng/mL 10 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Urine
3h 10m
sPECAM-1 Monkey ELISA 61-PECMK-E01 0.48–30 U/mL 0.06 U/mL 10 µL Cell Culture, Serum 3h 10m
sP-selectin ELISA 61-PSEHU-E01 0.63–40 ng/mL 0.20 ng/mL 10 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
2h 30m
sP-selectin Monkey ELISA 61-PSEMK-E01 0.8–50 U/mL 1.3 U/mL 10 µL Cell Culture, Serum 2h 30m
sPSGL-1 ELISA 61-PSGHU-E01 1.6–50 U/mL 1 U/mL 100 µL Cell Culture, Serum 3h 10m
ß Defensin 2 ELISA 30-6500 0.1–3 ng/mL 0.077 ng/mL 100 mg Stool 3h 30m
ß-4 Thymosin ELISA 30-9520 0.16–10 µg/mL 0.1 µg/mL 50 µL Serum, Tissue Culture 2h 20m
sTNF-R ELISA (60kDa) 61-TN6HU-E01 0.08–5 ng/mL 0.05 ng/mL 10 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
2h 10m
sTNF-R ELISA (80kDa) 61-TN8HU-E01 0.16–10 ng/mL 0.10 ng/mL 10 µL
Cell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Urine
2h 10m
sTNF-R I Monkey ELISA 61-TR1MK-E01 0.09–6 U/mL 0.06 U/mL 10 µL Cell Culture, Serum 2h 10m
sVAP-1 ELISA 61-VAPHU-E0131.3–2,000 pg/mL
19 pg/mL 10 µLAmniotic Fluids, Cell Culture, EDTA Plasma, Heparin Plasma, Serum
3h 10m
87
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
sVCAM-1 ELISA 61-VCAHU-E01 3.15–100 ng/mL 0.6 ng/mL 100 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
2h 10m
sVE-cadherin ELISA 61-VECHU-E01 0.16–10 ng/mL 0.1 ng/mL 20 µLCell Culture, Heparin Plasma, Serum
3h 10m
sVE-cadherin Monkey ELISA
61-VECMK-E01 0.19–12.5 U/mL 0.10 U/mL 20 µL Cell Culture, Serum 3h 10m
sVEGF-R1/FLT-1 ELISA 61-VGRHU-E01 0.16–10 ng/mL 0.03 ng/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
3h 30m
TGF ß-1 ELISA 20-TGF1HU-E01 19–600 pg/mL 1.9 pg/mL 10 µLCell Culture, Plasma, Serum
6h 45m
TGF ß-2 ELISA 20-TGF2HU-E0131.25–1,000 pg/mL
10 pg/mL 10 µLCell Culture, Plasma, Serum
5h 30m
TGF-ß1 Mouse ELISA 61-TB1MS-E0131.3–2,000 pg/mL
9 pg/mL 10 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
5h 30m
TGF-ß1 Rat ELISA 61-TB1RT-E0131.3–2,000 pg/mL
8 pg/mL 100 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
5h 30m
TGF-ß-2 ELISA 61-TB2HU-E01 31–1,000 pg/mL 6.6 pg/mL 100 µL Cell Culture, Serum 5h 35m
Thiostatin Rat ELISA 41-THIRT-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Serum 2h 10m
Thymulin ELISA 30-9810 0.03–16 ng/mL 0.03 ng/mL 50 µL Serum Overnight
TIE-2 ELISA 61-TIEHU-E01 0.16–10 ng/mL 0.03 ng/mL 10 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
Overnight
TIMP-1 ELISA 61-TIMHU-E01 39–2,500 pg/mL 10 pg/mL 20 µLCell Culture, EDTA Plasma, Heparin Plasma, Serum
3h 10m
TNF-ß ELISA 61-TNBHU-E0115.6–1,000 pg/mL
4.6 pg/mL 100 µLCell Culture, Plasma, Serum
4h 10m
TNF-α ELISA 45-TNFHU-E05 15–1,500 pg/mL 1.7 pg/mL 100 µLCell Culture, Plasma, Serum
4h
TNF-α ELISA 45-TNFHU-E0115.6–1,500 pg/mL
1.7 pg/mL 100 µLCell Culture, Plasma, Serum
4h
TNF-α Monkey ELISA 61-TNAMK-E01 28.1–1,800 U/mL 6 U/mL 50 µL Cell Culture, Serum 3h 10m
TNF-α Mouse ELISA 61-TNFMS-E0115.6–1,000 pg/mL
3 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
4h 10m
TNF-α Porcine ELISA 45-TNFPO-E01.123.4–1,500 pg/mL
4 pg/mL 50 µLCell Culture, EDTA Plasma, Serum
5h
TNF-α Rat ELISA 61-TNART-E0139.1–2,500 pg/mL
11 pg/mL 50 µL Cell Culture, Serum 3h 10m
Immunology
88
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
TNF-α Ultrasensitive ELISA 45-TNFHUU-E01 0.5–32 pg/mL 0.09 pg/mL 50 µLCell Culture, Plasma, Serum
3h
TNF-α Ultrasensitive ELISA 45-TNFHUU-E05 0.5–32 pg/mL 0.09 pg/mL 50 µLCell Culture, Plasma, Serum
3h
TNF-α-Blocker Monitoring ELISA (Humira®)
30-9657 0.625–20 µg/mL 0.4 µg/L 5 µL Serum 5h 20m
TNF-α-Blocker Monitoring ELISA (Remicade®)
30-9655 0.53–45 µg/mL 0.4 µg/L 5 µL Serum 5h 20m
ToxoPlasma IgG Ab ELISA 27-GD80Cut-off: See Protocol
See Protocol 5 µL Plasma, Serum See Protocol
TRAIL ELISA 61-TRAHU-E0115.6–1,000 pg/mL
5 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h
VEGF ELISA 45-VEGHU-E01 23–1,500 pg/mL 5 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Serum
4h
VEGF-A ELISA 61-VGAHU-E0115.6–1,000 pg/mL
7.9 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
4h 30m
VEGF-A Mouse ELISA 61-VGAMS-E0162.5–4,000 pg/mL
20 pg/mL 50 µLCell Culture, EDTA Plasma, Serum
4h 30m
VEGF-C Rat ELISA 61-VGCRT-E01 47–3,000 pg/mL 27 pg/mL 50 µLCell Culture, Heparin Plasma, Serum
3h 30m
VEGF-R2/KDR ELISA 61-KDRHU-E01 78–5,000 pg/mL 7 pg/mL 50 µLCell Culture, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
3h 30m
VEGF-R3/FLT-4 ELISA 61-FLTHU-E01 0.6–40 ng/mL 0.03 ng/mL 50 µLCell Culture, Citrate Plasma, Serum
3h 30m
Visceral Leishmaniasis ELISA
65-VILHU-E01 See Protocol See Protocol 10 µL Serum 1h 16m
West Nile Virus IgG ELISA 65-WNGHU-E01 See Protocol See Protocol 4 µL Serum 2h 15m
West Nile Virus IgM ELISA 65-WNMHU-E01 * See Protocol See Protocol 4 µL Serum 3h 16m
Zonulin ELISA 30-5600 0–1,000 ng/mL 0.6 ng/mL 250 µL Stool 3h 10m
Zonulin ELISA (Serum) 30-5601 See Protocol 0.6 ng/mL See Protocol Serum 3h 10m
89
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Neurobiology
90
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Neurobiology brings together many disciplines including biochemistry, molecular
biology, anatomy, physiology and medicine to study the cells of the nervous system
and the organization of these cells into functional circuits that process information and
mediate behavior. ALPCO offers a number of relevant biomarker assays and formats
which can be used for the investigation of neurological function, diseases and disorders
of sensory information processing.
Peripheral Neuropathy
Ganglioside, MAG and SGPG ELISAs can aid in the
differentiation of neurological disorders including
Guillian Barré, Miller Fisher, and chronic inflammatory
demyelinating polyneuropathy.
Gangliosides
Gangliosides are glycosphingolipids containing sialic
acid residues which are particularly abundant in
membrane components of the peripheral nervous
system. Variances in ganglioside structure give rise
to numerous antibody targets where production
of certain anti-ganglioside autoantibodies can be
associated with specific neurological conditions.
Research has shown quantitative detection of these
anti-ganglioside titers may aid in the differential
determination of peripheral neuropathies.1
Neurological disorders can be caused by a variety
of systemic diseases, toxic exposures, medications,
infections, and hereditary disorders.2 Studies have
linked the presence of high anti-ganglioside titers
to several neuropathies including Guillain-Barré
Syndrome (GBS), Miller-Fisher Syndrome (MFS), Acute
Motor Axonal Neuropathy (AMAN), Multifocal Motor
Neuropathy (MMN), and Chronic Ataxic Neuropathy,
Opthalmoplegia, IgM Paraprotein, Agglutinin and
Disialosyl Antibodies (CANOMAD). Additionally,
correlations have been drawn between the severity of
the disorder and the isotype detected. IgG antibodies
Neurobiology
91
have been strongly associated with acute conditions
while IgM antibodies tend to present in chronic diseases.
Many of these neurological disorders exhibit similar
symptoms involving sensory loss and distal pain,
numbness, tingling and weakness, making them difficult
to dissociate. An increasing level of research indicates
immunological tests for ganglioside antibodies plays
an important role in the diagnosis and management of
neuromuscular diseases.3
MAG
The myelin-associated glycoprotein(MAG) is a
transmembrane glycoprotein localized in periaxonal
Schwann cells and ogliodendroglial membranes of myelin
sheaths. IgM antibodies in most neuropathy cases react
to the oligosaccharides (HNK-1 epitope) of glycolipids
and glycoproteins that are concentrated in the peripheral
nerves. This epitope is also shared by a number of
other neuropathy target antigens (i.e. gangliosides,
SGPG). Research has shown detection of anti-MAG IgM
autoantibodies, especially at high titers, is associated with
sensory-motor demyelinating peripheral neuropathies
and IgM gammopathy.4
SGPG
Antibodies recognizing MAG react with a carbohydrate
determinant that is also present on Sulfate-3-glucuronyl
paragloboside (SGPG). While MAG is restricted to
the periaxonal Schwann cell membranes, SGPG has a
wider distribution with presence in both Schwann cell
and neuronal membranes including myelin, axolemma,
and neural endothelial cells. Sensory demyelinating
neuropathies typically exhibit anti-MAG and anti-SGPG
activity but the presence of anti-SGPG antibodies may be
considered more characteristic of a non-demyelinating
motor neuropathy.5
1 Gorenjac, Maksimiljan. Clinical and Diagnostic Role of Ganglioside Antibody Testing. The Journal of The International Federation of Clinical Chemistry and
Laboratory Medicine. 2000; Vol15 No 3. <http://www.ifcc.org/ifccfiles/docs/150309200414.pdf>
2 Azhary, Hend. et al. Peripheral Neuropathy: Differential Diagnosis and Management. American Family Physician. Apr 2010; Vol 81: 887-892.
3 Winner, John. Antibodies and clinical neurological syndromes. The Biomedical Scientist. Jul 2006; 622-624.
4 Czaplinski, A. and Steck, A.J. Antibody testing in peripheral neuropathies. A critical approach. Schweizer Archiv für Neurologie und Psychiatry. Jul 2002; Vol
153 No 7: 301-7.
5 Neuromuscular Clinical Laboratory. Anti-SGPG antibodies. 2012. <http://neuromuscular.wustl.edu/over/labdis.html#sgpg>
Neurobiology
92
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
5a-Androstane-3a, 17b-diol Glucuronide ELISA
11-ANDHU-E01 0.25–50 ng/mL 0.1 ng/mL 50 µL Serum 45m
5-HIAA ELISA 17-5HIHU-E01 0.5–50 mg/L 0.17 mg/L 50 µL Urine 1h 15m
6-Sulfatoxymelatonin ELISA 01-EK-M6S 0.8–40 ng/mL 0.14 ng/mL 10 µL Urine 4h
α-MSH RIA 13-RB 303 4.7–150 pmol/L 3 pmol/L 100 µLCerebrospinal Fluid, Plasma
Overnight
ACTH ELISA 21-ACTHU-E01 * 5–500 pg/mL 0.46 pg/mL 200 µL Plasma 5h
Anti-GM1 Autoantibodies ELISA
01-EK-GM1-GM ^ Cut-off: See Protocol
See Protocol 20 µL Serum 4h 30m
Anti-IFN ß Binding Antibodies ELISA
01-EK-IFNB20–500 titer units
See Protocol 20 µL Serum 4h 30m
Anti-MAG Autoantibodies ELISA
01-EK-MAG ^ 1,000–70,000 titer units
See Protocol 2 µL Serum 4h 30m
Anti-SGPG Autoantibodies ELISA
01-EK-SGPG ^ Cut-off: See Protocol
See Protocol 2 µL Serum 4h 30m
Bi-CAT (Epinephrine & Norepinephrine) ELISA
17-BCTHU-E02.1 See Protocol See Protocol 300 µL, 10 µL Plasma, Urine 4h
Anti-Myelin Associated Glycoprotein (MAG) ELISAThe MAG assay utilizes a highly
purified MAG antigen from human
brain and studies have shown this
ELISA to be more sensitive than
western blot.6
6 Kuijf, M.L., et al. Detection of anti-MAG antibodies in polyneuropathy associated with IgM monoclonal gammopathy. Neurology. Sept 2009. Vol 73 No 9: 688-
95.
70605040302010
0
77%
BühlmannELISA
WB-a WB-b
44%54%
Anti-MAG ELISA detected 49 out of 68 total positives for
demyelinating polyneuropathy and IgM gammopathy.
View the anti-MAG assay 01-EK-MAG on page 93
93
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Bi-CAT (Epinephrine & Norepinephrine)
Research ELISA17-BCTHU-E02-RES See Protocol See Protocol See Protocol Biological Fluids Overnight
Bi-CAT (Epinephrine & Norepinephrine) RIA
17-BCTHU-R200 See Protocol See Protocol 300 µL, 10 µL Plasma, Urine 4h
Bi-Neph (Metanephrine & Normetanephrine) ELISA
17-BINHU-E02-UFST See Protocol See Protocol 25 µL Urine 1h 45m
Bradykinin ELISA 48-BRAHU-E017.2–5,000 pg/well
7.2 pg/mL 10 µL Plasma, Urine Overnight
cAMP ELISA 55-AMPHU-E020.05–10 pMol/mL
0.1 pMol/mL 50 µL Plasma, Urine 3h 30m
cGMP ELISA 55-GMPHU-E020.05–10 pMol/mL
0.1 pMol/mL 50 µLCell Culture, Plasma, Urine
3h 30m
CGRP ELISA 32-54817.81–1,000 pg/mL
5 pg/mL 100 µL Plasma, Serum Overnight
CGRP Rat ELISA 32-5482 3.91–500 pg/mL 1 pg/mL 100 µLPlasma, Serum, Tissue Culture
Overnight
Chromogranin A ELISA 43-CHRHU-E01.2 31–830 ng/mL 5 ng/mL 50 µL EDTA Plasma 2h 20m
Chromogranin A RIA 13-RB 321 0.156–5 nmol/L 0.04 nmol/L 50 µL Plasma Overnight
CRF ELISA 20-CRFHU-E010.01–1,000 ng/mL
0.01 ng/mL 50 µL Plasma, Serum 4h
CRF-HS Mouse/Rat ELISA 48-CRFMS-E01 0.078–2.5 ng/mL 0.078 ng/mL 50 µL Plasma, Tissue Culture 8h 30m
Dopamine ELISA 17-DOPHU-E01.1 10–2,000 ng/mL 4.5 ng/mL 300 µL, 10 µL Plasma, Urine 4h
Dopamine Research ELISA 17-DOPHU-E01-RES 0.5–80 ng/mL See Protocol See Protocol Biological Fluids Overnight
Dopamine RIA 17-DOPHU-R100 10–2,000 ng/mL 4.5 ng/mL 300 µL, 10 µL Plasma, Urine 4h
Epinephrine ELISA 17-EPIHU-E01.1 1–200 ng/mL 0.3 ng/mL 300 µL, 10 µL Plasma, Urine 4h
Epinephrine Research ELISA 17-EPIHU-E01-RES 0.5–80 ng/mL See Protocol See Protocol Biological Fluids Overnight
Epinephrine RIA 17-EPIHU-R100 1–200 ng/mL 0.3 ng/mL 300 µL, 10 µL Plasma, Urine 4h
GABA ELISA 17-GABHU-E01 15–1,500 ng/mL 7.5 ng/mL 300 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
Overnight
GanglioCombi® Anti-Ganglioside Auto
Antibody ELISA01-EK-GCO
Cut-off: See Protocol
See Protocol 30 µL Serum 4h 30m
GanglioCombi® Anti-Ganglioside Auto
Antibody ELISA (Dual Plate lgG and lgM)
01-EK-GCO-GMCut-off: See Protocol
See Protocol 30 µL Serum 4h 30m
GanglioCombi® Light Anti-Ganglioside ELISA
01-EK-GCL-GMCut-off: See Protocol
See Protocol 30 µL Serum 4h 30m
GFAP ELISA 32-5188 0.3–40 ng/mL 0.5 ng/mL 50 µL Cell Culture, Plasma 4h
Neurobiology
94
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
GanglioCombi® ELISAs The GanglioCombi® ELISA assays
provide a flexible format for IgM
and IgG detection of the most
relevant gangliosides. A proprietary
method for homogenous plate
coating minimizes inter/intra lot
and technician variation, offering a
reliable and cost effective method
for autoimmune ganglioside testing.
Flexible ELISA formats for
differentiation of neurological
disorders
• Mixed IgG/IgM conjugate
for screening
• Individual IgG/IgM conjugates
for differential determination
Simple, reliable, cost effective
method for routine use
• Quantitative
• 30 µL sample size
• Results in 4 hours 30 minutes
Proprietary method for homogenous
plate coating
• Minimal inter/intra lot and
technician variation
• No non-specific binding
Ability to compare results among all
Gangliocombi® assays
• Identical set of calibrator and
controls for all kits
Ganglioside Detection
Conjugate asialo-GM1 GM1 GM2 GD1a GD1b GQ1b
ü ü ü ü ü ü 50:50 Mixed IgG/IgM
ü ü ü ü ü ü Individual IgG and IgM
ü ü ü Individual IgG and IgM
ü Individual IgG and IgM
01-EK-GCO
01-EK-GCO-GM
01-EK-GCL-GM
01-EK-GM1-GM^
95
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
GHB Enzymatic Assay 01-KK-GHB 5–250 mg/L 1.5 mg/L 8 µL Serum, Urine 8m
Glutamate ELISA 17-GLUHU-E01 0.6–60 µg/mL 0.3 µg/ml 100 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
Overnight
Melatonin Direct Saliva RIA 01-RK-DSM2 0.5–50 pg/mL 0.3 pg/mL 400 µL Saliva Overnight
Melatonin ELISA (Direct Saliva)
01-EK-DSM.1 0.5–25 pg/mL 0.29 pg/mL 200 µL Saliva Overnight
Melatonin RIA 01-RK-MEL2 0.5–50 pg/mL 0.2 pg/mL 1 mL Plasma, Serum Overnight
Metanephrine ELISA (Plasma)
17-METHU-E01-FST 30–3,000 pg/mL 10 pg/mL 250 µL Plasma Overnight
Norepinephrine ELISA 17-NORHU-E01.1 5–1,000 ng/mL 1.5 ng/mL 300 µL, 10 µL Plasma, Urine 4h
Norepinephrine Research ELISA
17-NORHU-E01-RES 0.2–32 ng/mL See Protocol See Protocol Biological Fluids Overnight
Norepinephrine RIA 17-NORHU-R100 5–1,000 ng/mL 1.5 ng/mL 300 µL, 10 µL Plasma, Urine 4h
NPY RIA 13-NPYHU-R100 9.4–300 pmol/L 6 pmol/L 200 µL Plasma, Serum 48h
NSE ELISA 43-NSEHU-E01 5–178 ng/mL 1.2 ng/mL 10 µL Serum 1h 10m
PSA NCAM ELISA 67-ABC0027B 0.25–16 ng/mL 0.25 ng/mL 100 µLCell Culture, Plasma, Serum, Tissue Culture
Overnight
PYY ELISA 48-PYYHU-E01.1 0.082–20 ng/mL 0.082 ng/mL 50 µL Plasma, Serum Overnight
PYY Mouse/Rat ELISA 48-PYYRT-E01.1 0.15–12.5 ng/mL 0.31 ng/mL 25 µLEDTA Plasma, Plasma, Serum
Overnight
S100 ß ELISA 48-CBPHU-E01 0.078–5 ng/mL 0.078 ng/mL 20 µL Plasma 5h 30m
Serotonin ELISA 17-SERHU-E01-FST 15–2,500 ng/mL 5 ng/mL 25 µLCerebrospinal Fluid, Plasma, Platelets, Serum, Urine
1h 15m
Serotonin Research ELISA 17-SERHU-E01-RES 0.015–2.5 ng/mL See Protocol See Protocol Biological Fluids Overnight
Serotonin RIA 17-SERHU-R100 15–2,500 ng/mL 0.3 ng/mL 25 µL, 100 µLCerebrospinal Fluid, Plasma, Platelets, Serum, Urine
2h 15m
Serum Amyloid A ELISA 41-SAAHU-E01 0.157–10 ng/mL 0.157 ng/mL 10 µL Plasma, Serum 1h
Serum Amyloid P Mouse ELISA
41-SAPMS-E01 6.25–200 ng/mL 12.5 ng/mL 5 µL Plasma, Serum 2h 10m
Serum Amyloid P Rat ELISA 41-SAPRT-E01 2.5–160 ng/mL 2.5 ng/mL 5 µL Plasma, Serum 25m
Serum Amyloid ß Auto-Antibody ELISA
20-SABHU-E01 1–120 RTU See Protocol 20 µL Serum 2h 30m
ß Endorphin RIA 13-RB 301 15.6–500 pmol/L 3 pmol/L 3 mL Plasma Overnight
Tri-CAT (Epinephrine, Norepinephrine,
Dopamine) ELISA 17-TCTHU-E03.1 See Protocol See Protocol 300 µL, 10 µL Plasma, Urine 4h
Neurobiology
96
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Tri-CAT (Epinephrine, Norepinephrine, Dopamine)
Research ELISA17-TCTHU-E03-RES See Protocol See Protocol See Protocol Biological Fluids Overnight
Tri-CAT (Epinephrine, Norepinephrine,
Dopamine) RIA17-TCTHU-R300 See Protocol See Protocol 300 µL, 10 µL Plasma, Urine 4h
Tryptophan ELISA 17-TRPHU-E01 2.5–250 µg/mL 1.2 µg/mL 20 µL Plasma, Serum, Urine Overnight
Urocortin 2 Mouse ELISA 48-UR2MS-E01 0.81–200 ng/mL 0.82 ng/mL 20 µL Plasma, Serum Overnight
Urocortin 3 Mouse/Rat ELISA
48-UROMS-E01 0.41–100 ng/mL 0.137 ng/mL 25 µL Plasma, Serum Overnight
MelatoninMelatonin is a key modulator of seasonal and circadian
biorhythms. The synthesis and secretion of melatonin is
regulated by a circadian clock in the hypothalamus and is
synchronized by the diurnal light-dark cycle.
Offered exclusively from ALPCO, the Bühlmann portfolio
of melatonin assays utilizes the Kennaway G280 antibody
and provides the most sensitive detection of melatonin
across multiple biological samples.
View melatonin assays 01-RK-DSM2, 01-EK-DSM.1 and 01-RK-MEL2 on page 96
97
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Toxicology
98
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Toxicological side effects are a common obstacle in drug development pipelines and
often manifest in site-specific damage to vital organs, including the liver, kidney and heart.
Estimates of compound attrition from failure to meet safety endpoints are as high as 45%
in preclinical models and 40% for Phase I clinical trials.1 Now more than ever, labs engaged
in compound, drug and device screening and development are chartered with performing a
comprehensive survey of potential toxicological side effects as part of their routine practice.
ALPCO offers a wide range of preclinical species-specific assays that provide a means for
scientists to achieve their goals in this endeavor.
Hepatotoxicity
DILI can be hepatocellular or choleostatic in nature, but
because viral hepatitis, environmental toxins, or other
diseases present the same pathogenic findings as DILI,
even biopsy is not conclusive.2 Assessment of DILI has
primarily relied on the release of enzymes from necrotic
cells, functional indicators of hepatic activity or increases in
circulating bilirubin.3 Drug-induced liver injury has become
the single most common cause for removal of an approved
drug from market,4 so there continues to be a need for more
specific and sensitive markers of hepatocellular damage.
One such biomarker, α-GST, has been shown to outperform
transaminases as a safety marker in rat models, and may
offer the potential to more accurately assess compound
toxicity by supplementing current screening methods.5
Nephrotoxicity
Until recently, drug-induced acute kidney injury
(DIAKI) has been determined by measurement of
serum creatinine and blood urea nitrogen, both of
which become elevated after damage has occurred.
The advent of novel markers, such as NGAL and π-GST,
are allowing researchers to detect DIAKI earlier and
Toxicology
99
identify the site-specific injury.6,7 The work by the Critical
Path Institute’s Predictive Safety Testing Consortium has
identified and proposed seven new nonclinicalbiomarkers,
KIM-1, Albumin, Total Protein, β2-microglobulin, Cystatin
C, Clusterin and Trefoil Factor-3, for consideration by the
FDA, EMA and PDMA in the drug review process.
Cardiotoxicity
Cardiotoxicity can occur due to exposure to heavy metals,
recreational drugs or pharmaceutical compounds. It
is a common side effect of chemotherapeutic agents,
such as those in the Anthracycline class.9 Even the
newer biologic anticancer therapeutics, such as
Trastuzumab, carry high risks.10 Cardiotoxicity may be
as mild as electrocardiographic changes or arrhythmias,
but can progress to myocardial infraction and even
cardiomyopathy. Biomarkers of cardiomyocyte injury,
like Troponin I, ANP, BNP and CK-MB, may be helpful for
identification of risks associated with these agents.11
1 Suter L, Babiss LE, and Wheeldon EB. Toxicogenomics in predictive toxicology in
drug development. Chem Biology. Feb 2004; Vol 11 No 2: 161-171.
2 U.S. Department of Health and Human Services. Food and Drug Administration.
Center for Drug Evaluation and Research. Guidance for Industry, Drug-
Induced Liver Injury: Premarketing Clinical Evaluation. Washington: Office of
Communications, Division of Drug Information. Jul 2009.
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
1,25 (OH)2 Vitamin D ELISA 30-2112 5.1–200 pg/mL 4.8 pg/mL 500 µL Plasma, Serum Overnight
1,25 (OH)2 Vitamin D Extraction Kit
30-KM1100 See Protocol See Protocol 500 µL Plasma, Serum 1h 8m
α-1-Acid Glycoprotein Chicken ELISA
41-AGPCH-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 15m
α-1-Acid Glycoprotein ELISA
41-AGPHU-E01 5–320 ng/mL 5 ng/mL 5 µL Plasma, Serum 1h 15m
α-1-Acid Glycoprotein Rat ELISA
41-AGPRT-E01 12.5–400 ng/mL 12.5 ng/mL 5 µL Plasma, Serum 1h 20m
α-1-Microglobulin ELISA 30-6710 0.019–1.5 mg/L 0.006 mg/L 10 µL Plasma, Serum, Urine 4h 45m
α-2-Macroglobulin ELISA 30-6610 0.07–5 mg/L 0.05 mg/L 10 µL Plasma, Serum, Stool 2h 15m
α-2-Macroglobulin Rabbit ELISA
41-A2MRB-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 15m
α-2-Macroglobulin Rat ELISA
41-A2MRT-E01 6.25–400 ng/mL 6.24 ng/mL 5 µL Plasma, Serum 1h 20m
α-GST ELISA 69-AGTHU-E01 2.5–80 µg/L 1.9 µg/L 50 µL Plasma, Serum, Urine 2h
Toxicology
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Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
3 Lee WM and Senior JR. Recognizing drug-induced liver injury: current problems,
possible solutions. Toxicol Pathology. 2005; Vol 33 No 1: 155-164.
4 Temple RJ and Himmel MH. Safety of newly approved drugs: implications for
prescribing. JAMA. May 2002; Vol 287 No 17: 2273–2275.
5 Clarke H, et al. Alpha-glutathione s-transferase (alpha-GST) release, an early
indicator of carbon tetrachloride hepatotoxicity in the rat. Hum Exp Toxicology.
Mar 1997; Vol 16 No 3: 154-157.
6 Mishra J, Ma Q, Prada A, et al. Identification of neutrophil gelatinase-associated
lipocalin as a novel urinary biomarker for ischemic injury. J Am Soc Nephrology.
Oct 2003; Vol 14 No 10: 2534–2543.
7 Koyner JL, et al. Urinary Biomarkers in the Clinical Prognosis and Early
Detection of Acute Kidney Injury. Clin J Am Soc Nephrology. Dec 2010; Vol 5 No
12: 2154-2165.
8 Dieterle F, et al. Renal biomarker qualification submission: a dialog between the
FDA-EMEA and Predictive Safety Testing Consortium. Nat Biotechnology. May
2010; Vol 28 No 5:455-462.
9 Ewer MS and Ewer SM. Cardiotoxicity of anticancer treatments: what the
cardiologist needs to know. Nat Rev Cardiology. Oct 2010; Vol 7 No 10: 564-
575.
10 Cardinale D, et al. Trastuzumab-Induced Cardiotoxicity: Clinical and Prognostic
Implications of Troponin I Evaluation. J Clin Oncology. Sep 2010; Vol 25 No 28:
3910-3916.
11 Gharib MI and Burnett AK. Chemotherapy-induced cardiotoxicity: current
practice and prospects of prophylaxis. Eur J Heart Fail. Jun 2002; Vol 4 No 3:
235-242.
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
ß-2 Microglobulin ELISA 25-BMGHU-E01 * 0.625–10 µg/mL 0.1 µg/mL 10 µL Serum 1h 20m
ß-2 Microglobulin Rat ELISA 41-MICRT-E01 25–800 ng/mL 25 ng/mL 10 µL Plasma, Serum 1h 30m
AFP ELISA 25-AFPHU-E01 5–300 ng/mL 2 ng/mL 20 µL Serum 1h 20m
Albumin Canine ELISA 41-ALBCA-E01 12.5–400 ng/mL 12.5 ng/mL 5 µL Plasma, Serum 1h 45m
Albumin ELISA 30-6330 12.5–800 µg/L 12.5 µg/L 100 mg, 10 µL Stool, Urine 2h 20m
Albumin Monkey ELISA 41-ALBMK-E01 12.5–400 ng/mL 12.5 ng/mL 100 µL Serum, Tissue Culture 1h 40m
Albumin Mouse ELISA 41-ALBMS-E01 7.8–500 ng/mL 5 ng/mL 2 µL Plasma, Serum, Urine 1h 10m
Albumin Porcine ELISA 41-ALBPO-E01 12.5–400 ng/mL See Protocol 5 µL Plasma, Serum, Urine 1h 40m
Albumin Rat ELISA 41-ALBRT-E01 6.25–400 ng/mL 5 ng/mL 5 µL Plasma, Serum, Urine 1h 10m
Amanitin ELISA 01-EK-AM1 1–100 ng/mL 0.22 ng/mL 40 µL Plasma, Serum, Urine 1h
ANP Rat ELISA 32-510315.6–2,000 pg/mL
15.6 pg/mL 50 µLCitrate Plasma, EDTA Plasma
Overnight
ANP RIA 13-BANI 1 7.8–1,000 pg/mL 3.5 pg/mL 500 µL Plasma Overnight
101
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
BNP Fragment ELISA (Nt-proBNP 8-29)
04-BI-20852W 5–1,000 fmol/mL 5 fmol/mL 35 µLCell Culture, Plasma, Serum
Overnight
Clusterin Rat ELISA 41-CLURT-E01 12.5–800 ng/mL 12.5 ng/mL 5 µL Plasma, Serum, Urine 1h 30m
Creatine Kinase ELISA 25-CKMHU-E01 7.5–200 ng/mL 7.5 ng/mL 20 µL Serum 1h 20m
Cystatin C ELISA 41-CYCHU-E010.7815–50 ng/mL
0.7815 ng/mL 5 µL Plasma, Serum 1h
Cystatin C Monkey ELISA 41-CYCMK-E01 0.125–4 ng/mL See Protocol 5 µL Plasma, Serum 1h 50m
Cystatin C Mouse ELISA 41-CYCMS-E01 1.25–40 ng/mL 1.25 ng/mL 2 µL Plasma, Serum 1h 40m
Cystatin C PETIA 01-KK-CYC * 0.4–8 mg/L 0.33 mg/L 2 µL Plasma, Serum 10m
Cystatin C PETIA 01-KK-CYC-6 * 0.4–8 mg/L 0.33 mg/L 2 µL Plasma, Serum 10m
Cystatin C Rat ELISA 41-CYCRT-E01 2.63–20 ng/mL 2.63 ng/mL 5 µL Plasma, Serum 1h 45m
Endostatin ELISA 04-BI-20742 0–80 nmol/L 0.2 nmol/L 10 µLCitrate Plasma, EDTA Plasma, Heparin Plasma, Serum
4h 30m
GHB Enzymatic Assay 01-KK-GHB 5–250 mg/L 1.5 mg/L 8 µL Serum, Urine 8m
GST Yb1 Rat ELISA 41-YGTRT-E01 3.12–100 ng/mL 3.12 ng/mL 5 µL Plasma, Serum, Urine 2h 10m
Haptoglobin Bovine ELISA 41-HAPBO-E0115.6–1,000 ng/mL
15.6 ng/mL 5 µL Plasma, Serum 40m
Haptoglobin Canine ELISA 41-HAPCA-E01 7.81–125 ng/mL 5 ng/mL 5 µL Plasma, Serum 40m
Haptoglobin ELISA 41-HAPHU-E013.125–200 ng/mL
3.125 ng/mL 100 µL Plasma, Serum 35m
Haptoglobin Equine ELISA 41-HAPEQ-E0118.75–600 ng/mL
18.75 ng/mL 5 µL Plasma, Serum 1h 15m
Haptoglobin Feline ELISA 41-HAPFE-E01 6.25–400 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 15m
Haptoglobin Mouse ELISA 41-HAPMS-E01 7.81–125 ng/mL 5 ng/mL 5 µL Plasma, Serum 35m
Haptoglobin Porcine ELISA 41-HAPPO-E01 25–400 ng/mL 5 ng/mL 5 µL Plasma, Serum 40m
Haptoglobin Rabbit ELISA 41-HAPRB-E01 6.25–200 ng/mL 6.25 ng/mL 5 µL Plasma, Serum 1h 30m
Haptoglobin Rat ELISA 41-HAPRT-E01 7.81–125 ng/mL 5 ng/mL 5 µL Plasma, Serum 35m
KIM-1 ELISA 41-KIMHU-E01 0.156–10 ng/mL 0.156 ng/mL 100 µL Plasma, Serum, Urine 1h 40m
KIM-1 Mouse ELISA 41-KIMMS-E01 0.078–5 ng/mL 0.078 ng/mL 100 µL Serum, Urine 2h 40m
KIM-1 Rat ELISA 41-KIMRT-E01 0.156–10 ng/mL 0.156 ng/mL 50 µL Serum, Urine 3h 15m
L-FABP ELISA 41-LFAHU-E01 1–32 ng/mL 1 ng/mL 50 µL Plasma, Serum 1h 15m
L-FABP Rat ELISA 41-LFART-E01 12.5–400 ng/mL 12.5 ng/mL 20 µL Plasma, Serum 1h 30m
Microalbumin ELISA 24-MABHU-E01 0.5–100 µg/mL 0.24 µg/mL 10 µL Urine 40m
Toxicology
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Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
Myoglobin ELISA 25-MYOHU-E01 * 25–1,000 ng/mL 25 ng/mL 20 µL Serum 1h 5m
Myoglobin ELISA 24-MYOHU-E01 0–250 ng/mL 6.25 ng/mL 10 µL Serum, Urine 30m
Myoglobin Mouse ELISA 41-MYOMS-E01 4.69–300 ng/mL 4.69 ng/mL 30 µL Plasma, Serum 1h 40m
Myoglobin Rat ELISA 41-MYORT-E013.125–200 ng/mL
3.125 ng/mL 75 µL Serum 1h 25m
NAG Reagent Set (300) * 73-1290050 0.25–200 U/L 0.25 U/L 10 µL Plasma, Serum, Urine 15m
NAG Reagent Set (5x60) * 73-1085 0.25–200 U/L 0.25 U/L 10 µL Plasma, Serum, Urine 15m
NAG Reagent Set (600) * 73-1290100 0.25–200 U/L 0.25 U/L 10 µL Plasma, Serum, Urine 15m
NAG Spectrophotometric Assay (320)
73-130050 0.16–33 U/L 0.16 U/L 50 µL Plasma, Serum, Urine 30m
NAG Spectrophotometric Assay (640)
73-130100 0.16–33 U/L 0.16 U/L 50 µL Plasma, Serum, Urine 30m
NGAL Canine ELISA 54-043 4–400 pg/mL 0.56 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Canine ELISA 54-043 4–400 pg/mL 0.56 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL ELISA 54-036 10–1,000 pg/mL 4 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Mouse ELISA 54-042 10–500 pg/mL 0.75 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Porcine ELISA 54-044 10–400 pg/mL 1 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
NGAL Rapid ELISA 54-037 0.2–20 ng/mL 0.008 ng/mL 10 µLEDTA Plasma, Plasma, Serum, Urine
1h
NGAL Rat ELISA 54-046 4–400 pg/mL 0.5 pg/mL 10 µLCell Culture, Plasma, Serum, Tissue Culture, Urine
3h 10m
Osteopontin ELISA 41-OPNHU-E01 0.31–20 ng/mL 0.05 ng/mL 10 µL Heparin Plasma, Urine 3h
Osteopontin Mouse ELISA 41-OPNMS-E01 0.03–2 ng/mL 0.015 ng/mL 5 µL Plasma 3h
Pi GST ELISA 69-PGTHU-E01 1.25–40 µg/L 1.3 µg/L 125 µL Urine 2h 15m
Prealbumin ELISA 30-6331 1.6–100 ng/mL 3 ng/mL 100 mg Plasma, Serum, Stool 2h 15m
Prealbumin Mouse ELISA 41-PALMS-E0115.625–500 ng/mL
15.625 ng/mL 5 µL Plasma, Serum 1h
Prealbumin Rat ELISA 41-PALRT-E0115.625–500 ng/mL
15.625 ng/mL 5 µL Plasma, Serum 1h
103
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Description Catalog # Range Sensitivity Sample Size Sample Type Incubation
proANP ELISA (1-98) 04-BI-20892 0.63–10 nmol/L 0.05 nmol/L 10 µLCell Culture, Plasma, Urine
4h
Procollagen III Peptide RIA 72-OCFK07-PIIIP 0.1–14 U/mL 0.1 U/mL 20 µL Plasma, Serum 5h
RBP4 Mouse ELISA 41-RBPMS-E01 0.625–20 ng/mL See Protocol 5 µL Plasma, Serum 1h 10m
RBP4 Rat ELISA 41-RBPRT-E01 6.25–200 ng/mL See Protocol 5 µL Plasma, Serum, Urine 1h 30m
Type IV Collagen ELISA (Serum)
69-C4SHU-E01 15.6–1,000 µg/L 15.6 µg/L 20 µL Serum 1h
Type IV Collagen ELISA (Urinary)
69-C4UHU-E01 0.8–50 µg/L 0.8 µg/L 50 µL Urine Overnight
Vitamin D Binding Protein ELISA
30-2314 2.2–60 ng/mL 1.23 ng/mL 10 µL Plasma, Serum, Urine 2h 20m
Vitamin D Binding Protein Rat ELISA
41-VDBRT-E013.125–100 ng/mL
3.125 ng/mL 5 µL Plasma, Serum 1h 30m
Toxicology
104
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
Immunology
106
Flow Cytometry
106
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Flow cytometry is a technique used to evaluate single cell properties, including
relative size, internal complexity and relative fluorescent intensity. Flow cytometry
has applications in a number of fields such as molecular biology, pathology,
immunology and medicine. Within the field of medicine, it is frequently used in
transplantation, hematology and tumor immunology. ALPCO offers a broad range
of unique and affordable flow cytometry solutions that can be used to study any
application of interest.
EuroFlow™ Panels
ALPCO provides validated EuroFlow™ 8-color antibody
panels for immunophenotyping and identification of
hematological malignancies. The single-tube screening
panels and multi-tube classification panels fit into the
EuroFlow™ consortium’s algorithm with entries defined by
the consortium’s standardized laboratory parameters.1
Two groups of markers are combined in each
8-color tube:
1. Backbone markers to identify distinct cell
populations in a sample, and
2. Markers for characterization of specific cell
populations
EuroFlow™ Panels and Infinicyt™ Software
1 Van Dongen JJM et al. EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and
malignant leukocytes. Leukemia. Sep 2012; Vol 26 No 9: 1908–1975.
Flow Cytometry
107107
Single Color Antibodies Catalog # Clone Isotype Excitation Laser
CD1a APC 71-HCD1A-A HI149 IgG1 Red
CD1a PerCP 71-HCD1A-PC HI149 IgG1 Blue
CD2 APC 71-HCD2-A TP1/31 IgG1 Red
CD2 APC-C750 70-2AC750 LT2 IgG2b Red
CD2 CF-Blue 71-HCD2-CB TP1/31 IgG1 Violet
CD2 PerCP 71-HCD2-PC TP1/31 IgG1 Blue
CD3 APC 71-HCD3-A 33-2A3 IgG2a Red
CD3 APC 70-3AP6 33-2A3 IgG2a Red
CD3 APC-C750 70-3AC750 UCHT-1 IgG1 Red
CD3 CF-Blue 71-HCD3-CB UCHT1 IgG1 Violet
CD3 DY-634 71-HCD3-DY 33-2A3 IgG2a Red
CD3 FITC 70-3F8 Cris-7 IgG2a Blue
CD3 OC-515 71-HCD3-OC 33-2A3 IgG2a Violet
CD3 OC-515 71-HCD3-OC.2 UCHT1 IgG1 Violet
CD3 PE 70-3PE5 33-2A3 IgG2a Blue
CD3 PerCP 71-HCD3-PC 33-2A3 IgG2a Blue
CD4 APC 71-HCD4-A HP2/6 IgG2a Red
CD4 FITC 70-4F5 Edu-2 IgG2a Blue
In multi-tube panels, the backbone markers are optimally
placed at the same fluorochrome position in every tube
in order to provide identical multidimensional localization
of the target cell population(s). The characterization
markers are positioned according to the utility of the
combined markers.
Infinicyt™
Infinicyt™ is a flow cytometry analysis software program
that provides an innovative approach for data integration
and multidimensional analysis of flow cytometry data. Its
state-of-the-art features make analysis and interpretation
of results easier, faster and more accurate. It is
recommended by the EuroFlow™ Consortium.
Immunology
108
Flow Cytometry
108
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Single Color Antibodies Catalog # Clone Isotype Excitation Laser
CD4 OC-515 71-HCD4-OC HP2/6 IgG2a Violet
CD4 Pacific Blue 70-4PBZ ‡ H2P/6 IgG2a Violet
CD4 PE 71-HCD4-PE HP2/6 IgG2a Blue
CD4 PerCP 71-HCD4-PC HP2/6 IgG2a Blue
CD4 PerCP-Cy5.5 70-4C5 ‡ SK3 IgG1 Blue
CD5 APC 71-HCD5-A 33-1C5 IgG2a Red
CD5 CF-Blue 71-HCD5-CB 33-1C5 IgG2a Violet
CD5 OC-515 71-HCD5-OC 33-1C5 IgG2a Violet
CD5 PerCP 71-HCD5-PC 33-1C5 IgG2a Blue
CD5 PerCP-Cy5.5 70-5C ‡ UCHT2 IgG1 Blue
CD6 APC 71-HCD6-A MAE-1C10 IgG1 Red
CD6 Biotin 71-HCD6-B MAE-1C10 IgG1 n/a
CD6 CF-Blue 71-HCD6-CB MAE-1C10 IgG1 Violet
CD6 FITC 71-HCD6-F MAE-1C10 IgG1 Blue
CD6 PE 71-HCD6-PE MAE-1C10 IgG1 Blue
CD7 APC 70-7AP4 ‡ CD7-6B7 IgG2a Red
CD7 APC 71-HCD7-A HIT7 IgG1 Red
CD7 Biotin 71-HCD7-B HIT7 IgG1 n/a
CD7 CF-Blue 71-HCD7-CB HIT7 IgG1 Violet
CD7 FITC 71-HCD7-F HIT7 IgG1 Blue
CD8 APC 71-HCD8-A 143-44 IgG1 Red
35-DSMHU-E01 3 - 300 U/mL 1.0 U/mL Serum
CD8 APC 71-HCD8-A.2 MEM-31 IgG2a Red
CD8 Biotin 71-HCD8-B 143-44 IgG1 n/a
CD8 CF-Blue 71-HCD8-CB 143-44 IgG1 Violet
CD8 DY-634 71-HCD8-DY 143-44 IgG1 Red
CD8 FITC 70-8F8 ‡ UCHT-4 IgG2a Blue
CD8 OC-515 71-HCD8-OC 143-44 IgG1 Violet
109109
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Single Color Antibodies Catalog # Clone Isotype Excitation Laser
CD8 PerCP 71-HCD8-PC 143-44 IgG1 Blue
CD9 APC 71-HCD9-A VJ1/20 IgG2a Red
CD9 Biotin 71-HCD9-B VJ1/20 IgG2a n/a
CD9 CF-Blue 71-HCD9-CB VJ1/20 IgG2a Violet
CD9 OC-515 71-HCD9-OC VJ1/20 IgG2a Violet
CD9 PerCP 71-HCD9-PC VJ1/20 IgG2a Blue
CD10 APC 71-HCD10-A HI10a IgG1 Red
CD10 APC-C750 70-10AC750 ‡ HI10a IgG1 Red
CD10 CF-Blue 71-HCD10-CB HI10a IgG1 Violet
CD10 FITC 71-HCD10-F HI10a IgG1 Blue
CD10 PerCP 71-HCD10-PC HI10a IgG1 Blue
CD11a APC 71-HCD11A-A TP1/40 IgG1 Red
CD11a CF-Blue 71-HCD11A-CB TP1/40 IgG1 Violet
CD11a OC-515 71-HCD11A-OC TP1/40 IgG1 Violet
CD11b APC 71-HCD11B-A DCIS1/18 IgG2a Red
CD11b CF-Blue 71-HCD11B-CB DCIS1/18 IgG2a Violet
CD11b FITC 71-HCD11B-F DCIS1/18 IgG2a Blue
CD11b OC-515 71-HCD11B-OC DCIS1/18 IgG2a Violet
CD11b PerCP 71-HCD11B-PC DCIS1/18 IgG2a Blue
CD11c PerCP 71-HCD11C-PC BU-15 IgG1 Blue
CD14 APC 70-14AP3 ‡ 47-3D6 IgG1 Red
CD14 Biotin 71-HCD14-B 47-3D6 IgG1 n/a
CD14 CF-Blue 71-HCD14-CB 47-3D6 IgG1 Violet
CD14 OC-515 71-HCD14-OC 47-3D6 IgG1 Violet
CD14 PerCP 71-HCD14-PC 47-3D6 IgG1 Blue
CD15 CF-Blue 71-HCD15-CB MCS-1 IgG1 Violet
CD15 PerCP 71-HCD15-PC MCS-1 IgG1 Blue
CD16 APC 71-HCD16-A 3G8 IgG1 Red
Immunology
110
Flow Cytometry
110
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Single Color Antibodies Catalog # Clone Isotype Excitation Laser
CD16 Biotin 71-HCD16-B 3G8 IgG1 n/a
CD16 CF-Blue 71-HCD16-CB 3G8 IgG1 Violet
CD16 FITC 71-HCD16-F 3G8 IgG1 Blue
CD16 FITC 71-HCD16-F.2 GRM1 IgG1 Blue
CD16 PE 71-HCD16-PE 3G8 IgG1 Blue
CD16 PerCP 71-HCD16-PC 3G8 IgG1 Blue
CD18 APC 71-HCD18-A GRF1 IgG1 Red
CD18 Biotin 71-HCD18-B GRF1 IgG1 n/a
CD18 CF-Blue 71-HCD18-CB GRF1 IgG1 Violet
CD18 FITC 71-HCD18-F GRF1 IgG1 Blue
CD18 OC-515 71-HCD18-OC GRF1 IgG1 Violet
CD19 APC 71-HCD19-A A3-B1 IgG2a Red
CD19 CF-Blue 71-HCD19-CB A3-B1 IgG2a Violet
CD19 FITC 70-19F4 HD37 IgG1 Blue
CD19 PECy5 70-19C2 J4.119 IgG1 Blue
CD19 PECy7 70-19C5 ‡ J4.119 IgG1 Blue
CD19 PerCP 71-HCD19-PC A3-B1 IgG2a Blue
CD19 PerCP-Cy5.5 70-19C7 HIB19 IgG1 Blue
CD20 APC 71-HCD20-A LT20 IgG1 Red
CD20 Biotin 71-HCD20-B LT20 IgG1 n/a
CD20 FITC 70-20F3 2H7 IgG2b Blue
CD20 Pacific Blue 70-20PBZ ‡ 2H7 IgG2b Violet
CD20 PerCP 71-HCD20-PC LT20 IgG1 Blue
CD21 APC-C750 70-21AC750 ‡ B-ly4 IgG1 Red
CD21 CF-Blue 71-HCD21-CB HI21a IgG2a Violet
CD21 FITC 71-HCD21-F HI21a IgG2a Blue
CD22 APC 71-HCD22-A HIB22 IgG1 Red
CD22 APC-C750 70-22AC750 ‡ MEM-01 IgG1 Red
111111
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Single Color Antibodies Catalog # Clone Isotype Excitation Laser
CD22 CF-Blue 71-HCD22-CB HIB22 IgG1 Violet
CD22 FITC 71-HCD22-F HIB22 IgG1 Blue
CD22 PE 71-HCD22-PE HIB22 IgG1 Blue
CD23 FITC 71-HCD23-F B-G6 IgG1 Blue
CD24 APC 71-HCD24-A SN3 IgG1 Red
CD25 APC 71-HCD25-A TP1/6 IgG2b Red
CD25 CF-Blue 71-HCD25-CB TP1/6 IgG2b Violet
CD25 PerCP 71-HCD25-PC TP1/6 IgG2b Blue
CD26 APC 71-HCD26-A TP1/19 IgG2b Red
CD26 Biotin 71-HCD26-B TP1/19 IgG2b n/a
CD26 CF-Blue 71-HCD26-CB TP1/19 IgG2b Violet
CD26 PerCP 71-HCD26-PC TP1/19 IgG2b Blue
CD28 FITC 71-HCD28-F KOLT-2 IgG1 Blue
CD29 APC 71-HCD29-A VJ1/14 IgG2b Red
CD29 Biotin 71-HCD29-B VJ1/14 IgG2b n/a
CD29 CF-Blue 71-HCD29-CB VJ1/14 IgG2b Violet
CD29 OC-515 71-HCD29-OC VJ1/14 IgG2b Violet
CD29 PerCP 71-HCD29-PC VJ1/14 IgG2b Blue
CD31 Biotin 71-HCD31-B TP1/15 IgG2a n/a
CD31 CF-Blue 71-HCD31-CB TP1/15 IgG2a Violet
CD31 OC-515 71-HCD31-OC TP1/15 IgG2a Violet
CD33 APC 71-HCD33-A HIM3-4 IgG1 Red
CD33 Biotin 71-HCD33-B HIM3-4 IgG1 n/a
CD33 CF-Blue 71-HCD33-CB HIM3-4 IgG1 Violet
CD36 FITC 71-HCD36-F TR9 IgG1 Blue
CD36 PE 71-HCD36-PE TR9 IgG1 Blue
CD38 APC-C750 70-38AC750 ‡ LD38 IgG1 Red
CD38 CF-Blue 71-HCD38-CB GR7A4 IgG1 Violet
Immunology
112
Flow Cytometry
112
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Single Color Antibodies Catalog # Clone Isotype Excitation Laser
CD38 DY-634 71-HCD38-DY GR7A4 IgG1 Red
CD38 FITC 70-38F LD38 IgG1 Blue
CD38 OC-515 71-HCD38-OC GR7A4 IgG1 Violet
CD40 APC 71-HCD40-A HI40a IgG1 Red
CD40 Biotin 71-HCD40-B HI40a IgG1 n/a
CD40 CF-Blue 71-HCD40-CB HI40a IgG1 Violet
CD40 PerCP 71-HCD40-PC HI40a IgG1 Blue
CD41 APC 71-HCD41-A HIP8 IgG1 Red
CD41 Biotin 71-HCD41-B HIP8 IgG1 n/a
CD41 CF-Blue 71-HCD41-CB HIP8 IgG1 Violet
CD41 FITC 71-HCD41-F HIP8 IgG1 Blue
CD41 PerCP 71-HCD41-PC HIP8 IgG1 Blue
CD42a APC 71-HCD42A-A GR-P IgG2a Red
CD42a Biotin 71-HCD42A-B GR-P IgG2a n/a
CD42a CF-Blue 71-HCD42A-CB GR-P IgG2a Violet
CD42a FITC 71-HCD42A-F GR-P IgG2a Blue
CD42a OC-515 71-HCD42A-OC GR-P IgG2a Violet
CD42a PE 71-HCD42A-PE GR-P IgG2a Blue
CD42a PerCP 71-HCD42A-PC GR-P IgG2a Blue
CD42a PURE 71-HCD42A-PU GR-P IgG2a n/a
CD42b APC 71-HCD42B-A HIP1 IgG1 Red
CD42b Biotin 71-HCD42B-B HIP1 IgG1 n/a
CD42b CF-Blue 71-HCD42B-CB HIP1 IgG1 Violet
CD42b FITC 71-HCD42B-F HIP1 IgG1 Blue
CD42b PerCP 71-HCD42B-PC HIP1 IgG1 Blue
CD43 Biotin 71-H43-B TP1/36 IgG1 n/a
CD43 CF-Blue 71-H43-CB TP1/36 IgG1 Violet
CD43 OC-515 71-HCD43-OC TP1/36 IgG1 Violet
113113
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Single Color Antibodies Catalog # Clone Isotype Excitation Laser
CD43 PerCP 71-HCD43-PC TP1/36 IgG1 Blue
CD44 APC 71-HCD44-A HI44a IgG1 Red
CD44 CF-Blue 71-HCD44-CB HI44a IgG1 Violet
CD44 PerCP 71-HCD44-PC HI44a IgG1 Blue
CD45 APC-C750 70-45AC750 ‡ GA90 IgG2a Red
CD45 CF-Blue 71-HCD45-CB D3/9 IgG1 Violet
CD45 CF-Blue 71-HCD45-CB.2 HI30 IgG1 Violet
CD45 DY-634 71-HCD45-DY D3/9 IgG1 Red
CD45 OC-515 71-HCD45-OC D3/9 IgG1 Violet
CD45 OC-515 70-45OC ‡ GA90 IgG2a Violet
CD45 PECy5 71-HCD45-PEC5 IMMU19.2 IgG1 Blue
CD45 PECy5 70-45C3 MMU19.2 IgG1 Blue
CD45 PerCP 71-HCD45-PC D3/9 IgG1 Blue
CD45 PerCP 71-HCD45-PC.2 HI30 IgG1 Blue
CD45RA APC 71-HCD45RA-A HI100 IgG1 Red
CD45RA CF-Blue 71-HCD45RA-CB GRT22 IgG1 Violet
CD45RA CF-Blue 71-HCD45RA-CB.2 HI100 IgG1 Violet
CD45RA PerCP 71-HCD45RA-PC HI100 IgG1 Blue
CD45RB APC 71-HCD45RB-A MC5/2 IgG1 Red
CD45RB CF-Blue 71-HCD45RB-CB MC5/2 IgG1 Violet
CD45RB FITC 71-HCD45RB-F MC5/2 IgG1 Blue
CD45RC APC 71-HCD45RC-A RP1/12 IgG1 Red
CD45RC FITC 71-HCD45RC-F RP1/12 IgG1 Blue
CD45RC PURE 71-HCD45RC-PU RP1/12 IgG1 n/a
CD49b APC 71-HCD49B-A TEA1/41 IgG1 Red
CD49b CF-Blue 71-HCD49B-CB TEA1/41 IgG1 Violet
CD49b FITC 71-HCD49B-F TEA1/41 IgG1 Blue
CD49b PE 71-HCD49B-PE TEA1/41 IgG1 Blue
Immunology
114
Flow Cytometry
114
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Single Color Antibodies Catalog # Clone Isotype Excitation Laser
CD49c APC 71-HCD49C-A VJ1/6 IgG1 Red
CD49c CF-Blue 71-HCD49C-CB VJ1/6 IgG1 Violet
CD49c FITC 71-HCD49C-F VJ1/6 IgG1 Blue
CD49c PE 71-HCD49C-PE VJ1/6 IgG1 Blue
CD49d APC 71-HCD49D-A ALC1/1 IgG1 Red
CD49d Biotin 71-HCD49D-B ALC1/1 IgG1 n/a
CD49d CF-Blue 71-HCD49D-CB ALC1/1 IgG1 Violet
CD49d FITC 71-HCD49D-F ALC1/1 IgG1 Blue
CD49d PerCP 71-HCD49D-PC ALC1/1 IgG1 Blue
CD52 APC 71-HCD52-A HI186 IgG2b Red
CD52 Biotin 71-HCD52-B HI186 IgG2b n/a
CD52 CF-Blue 71-HCD52-CB HI186 IgG2b Violet
CD52 FITC 71-HCD52-F HI186 IgG2b Blue
CD52 PE 71-HCD52-PE HI186 IgG2b Blue
CD52 PerCP 71-HCD52-PC HI186 IgG2b Blue
CD53 APC 71-HCD53-A HI29 IgG1 Red
CD53 Biotin 71-HCD53-B HI29 IgG1 n/a
CD53 CF-Blue 71-HCD53-CB HI29 IgG1 Violet
CD53 FITC 71-HCD53-F HI29 IgG1 Blue
CD53 PE 71-HCD53-PE HI29 IgG1 Blue
CD53 PerCP 71-HCD53-PC HI29 IgG1 Blue
CD56 APC 71-HCD56-A B-A19 IgG1 Red
CD56 APC-C750 70-56AC750 ‡ C5.9 IgG2b Red
CD56 Biotin 71-HCD56-B B-A19 IgG1 n/a
CD56 PE 70-56PE ‡ C5.9 IgG2b Blue
CD56 PURE 71-HCD56-PU B-A19 IgG1 n/a
CD57 FITC 71-HCD57-F HI57a IgM Blue
CD57 PURE 71-HCD57-PU HI57a IgM n/a
115115
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Single Color Antibodies Catalog # Clone Isotype Excitation Laser
CD58 APC 71-HCD58-A HI58a IgG1 Red
CD58 CF-Blue 71-HCD58-CB HI58a IgG1 Violet
CD58 FITC 71-HCD58-F HI58a IgG1 Blue
CD58 PE 71-HCD58-PE HI58a IgG1 Blue
CD59 APC 71-HCD59-A VJ1/12,2 IgG2a Red
CD59 Biotin 71-HCD59-B VJ1/12,2 IgG2a n/a
CD59 CF-Blue 71-HCD59-CB VJ1/12,2 IgG2a Violet
CD59 FITC 71-HCD59-F VJ1/12,2 IgG2a Blue
CD59 OC-515 71-HCD59-OC VJ1/12,2 IgG2a Violet
CD59 PE 71-HCD59-PE VJ1/12,2 IgG2a Blue
CD59 PerCP 71-HCD59-PC VJ1/12,2 IgG2a Blue
CD61 PerCP 71-HCD61-PC C17 IgG1 Blue
CD62E APC 71-HCD62E-A TEA2/1 IgG2b Red
CD62E FITC 71-HCD62E-F TEA2/1 IgG2b Blue
CD62L APC 71-HCD62L-A HI62L IgG2a Red
CD62L CF-Blue 71-HCD62L-CB HI62L IgG2a Violet
CD62L PerCP 71-HCD62L-PC HI62L IgG2a Blue
CD62P APC 71-HCD62P-A P.seK02.22 IgG2b Red
CD62P CF-Blue 71-HCD62P-CB P.seK02.22 IgG2b Violet
CD62P PerCP 71-HCD62P-PC P.seK02.22 IgG2b Blue
CD63 APC 71-HCD63-A TEA3/18 IgG1 Red
CD63 Biotin 71-HCD63-B TEA3/18 IgG1 n/a
CD63 CF-Blue 71-HCD63-CB TEA3/18 IgG1 Violet
CD63 FITC 71-HCD63-F TEA3/18 IgG1 Blue
CD63 OC-515 71-HCD63-OC TEA3/18 IgG1 Violet
CD63 PE 71-HCD63-PE TEA3/18 IgG1 Blue
CD63 PerCP 71-HCD63-PC TEA3/18 IgG1 Blue
CD64 PE 71-HCD64-PE 10.1 IgG1 Blue
CD69 APC 71-HCD69-A FN50 IgG1 Red
Immunology
116
Flow Cytometry
116
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Single Color Antibodies Catalog # Clone Isotype Excitation Laser
CD71 CF-Blue 71-HCD71-CB FG2/12 IgG1 Violet
CD71 FITC 71-HCD71-F FG2/12 IgG1 Blue
CD71 PerCP 71-HCD71-PC FG2/12 IgG1 Blue
CD81 APC-C750 70-81AC750 ‡ M38 IgG1 Red
CD86 FITC 71-HCD86-F BU63 IgG1 Blue
CD98 APC 71-HCD98-A FG1/8 IgG1 Red
CD98 Biotin 71-HCD98-B FG1/8 IgG1 n/a
CD98 CF-Blue 71-HCD98-CB FG1/8 IgG1 Violet
CD98 PE 71-HCD98-PE FG1/8 IgG1 Blue
CD98 PerCP 71-HCD98-PC FG1/8 IgG1 Blue
CD99 APC 71-HCD99-A HI156 IgG2a Red
CD99 Biotin 71-HCD99-B HI156 IgG2a n/a
CD99 CF-Blue 71-HCD99-CB HI156 IgG2a Violet
CD99 FITC 71-HCD99-F HI156 IgG2a Blue
CD99 PerCP 71-HCD99-PC HI156 IgG2a Blue
CD105 APC 71-H105A-PC 2H6F11 IgG1 Red
CD105 CF-Blue 71-HCD105-CB 2H6F11 IgG1 Violet
CD105 OC-515 71-HCD105-OC 2H6F11 IgG1 Violet
CD105 PerCP 71-HCD105-PC 2H6F11 IgG1 Blue
CD117 APC 71-HCD117-A 104D2 IgG1 Red
CD138 APC-C750 70-138AC750 B-A38 IgG1 Red
CD138 FITC 70-138F4 B-A39 IgG2 Blue
CD138 PE 70-138PE4 B-A38 IgG1 Blue
CD147 APC 71-HCD147-A VJ1/9 IgG1 Red
CD147 CF-Blue 71-HCD147-CB VJ1/9 IgG1 Violet
CD147 FITC 71-HCD147-F VJ1/9 IgG1 Blue
CD147 PE 71-HCD147-PE VJ1/9 IgG1 Blue
CD147 PerCP 71-HCD147-PC VJ1/9 IgG1 Blue
CD235a APC 71-HC235A-A HI264 IgG2a Red
117117
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Single Color Antibodies Catalog # Clone Isotype Excitation Laser
CD235a CF-Blue 71-HC235A-CB HI264 IgG2a Violet
CD235a FITC 71-HC235A-F HI264 IgG2a Blue
CD235a PE 71-HC235A-PE HI264 IgG2a Blue
Anti Caspase-3 active PURE 71-HCASP3-PU IgG n/a
Anti-cKit PURE 71-HCKIT-PU IgG n/a
Anti-GST PURE 71-HGST-PU IM14/21 IgG n/a
Anti-IL8 PURE 71-HIL8-PU IL8-1505 IgG2a n/a
Anti-LMO1 PURE 71-HLMO1-PU LMO1-1201 IgG2a n/a
CPA APC 71-HCPA-A CA2 IgG Red
CycCD3 Pacific Blue 70-3PBZ ‡ UCHT-1 Violet
CyCD79a PE 70-79APE ‡ HM57 IgG1 Blue
CyMPO FITC 70-MPOF3 ‡ 2C7 IgG1 Blue
cyTCRβ APC 70-bF1AP 8A3 IgG1 Red
HLA-DP APC 71-HHLADP-A HI43 IgG1 Red
HLA-DP CF-Blue 71-HHLADP-CB HI43 IgG1 Violet
HLA-DP FITC 71-HHLADP-F HI43 IgG1 Blue
HLA-DP PE 71-HHLADP-PE HI43 IgG1 Blue
HLA-DP PURE 71-HHLADP-PU HI43 IgG1 n/a
HLA-DQ APC 71-HHLADQ-A HI118 IgG1 Red
HLA-DQ CF-Blue 71-HHLADQ-CB HI118 IgG1 Violet
HLA-DQ FITC 71-HHLADQ-F HI118 IgG1 Blue
HLA-DR APC 71-HHLADR-A GRB-1 IgG2a Red
HLA-DR Biotin 71-HHLADR-B GRB-1 IgG2a n/a
HLA-DR CF-Blue 71-HHLADR-CB GRB-1 IgG2a Violet
HLA-DR FITC 71-HHLADR-F GRB-1 IgG2a Blue
HLA-DR OC-515 71-HHLADR-OC GRB-1 IgG2a Violet
HLA-DR PE 71-HHLADR-PE GRB-1 IgG2a Blue
HLA-DR PerCP 71-HHLADR-PC GRB-1 IgG2a Blue
Immunology
118
Flow Cytometry
118
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Single Color Antibodies Catalog # Clone Isotype Excitation Laser
IREM-2 FITC 71-HIREM2-F UP-H2 IgG2a Blue
IREM-2 PerCP 71-HIREM2-PC UP-H2 IgG2a Blue
Kappa APC 70-KappaP Polyclonal Red
Kappa FITC 70-KAPPF2 Polyclonal Blue
Kappa PE 70-KAPPPE ‡ Polyclonal Blue
Lambda APC-C750 70-LAC750 ‡ Polyclonal Red
Lambda FITC 70-LAMBF ‡ Polyclonal Blue
Lambda APC 70-LAMBAP Polyclonal Red
Lambda APC 71-HLAMBD-A HIgλ IgG6 Red
Lambda-PE 70-LAMBPE Polyclonal Blue
Lambda CF-Blue 71-HLAMBDA-CB Higλ IgG7 Violet
Multicolor Combinations Catalog # Clone Isotype Excitation Laser
CD3 FITC/CD4 PE 70-3F8-4PE9 Cris-7, Edu-2 IgG2a, IgG2a Blue
CD3 FITC/CD8 PE 70-3F8-8PE4 Cris-7, 17D8 IgG2a, IgG1 Blue
CD3 FITC/CD16 PE 70-3F8-16PE7 Cris-7, 3G8 IgG2a , IgG1 Blue
CD3 FITC/CD19 PE 70-3F8-19PE5 Cris-7, HD37 IgG2a, IgG1 Blue
CD3 FITC/CD56 PE 70-3F8-56PE Cris-7, C5.9 IgG2a, IgG2b Blue
CD3 FITC/HLADR PE 70-3F8-DRPE Cris-7, 423L IgG2a, IgG2a Blue
CD4 FITC/CD8 PE 70-4F6-8PE4 Edu-2, 17D8 IgG2a, IgG1 Blue
CD4 FITC/CD45 PE 70-4F6-45PE4 Edu-2, D3/9 IgG2a, IgG1 Blue
CD5 FITC/CD19 PE 70-5F4-19PE5 MCD5, HD37 IgG2b, IgG1 Blue
CD8 FITC/CD16 PE 70-8F8-16PE7 UCH-T4, 3G8 IgG2a, IgG1 Blue
CD8 FITC/CD56 PE 70-8F8-56PE UCH-T4, C5.9 IgG2a, IgG2b Blue
CD45 FITC/CD14PE 70-45F5-14PE3 EO1, 47-3D6 gG2a, IgG1 Blue
HLA B27 FITC/HLA B7 PE 70-COMB1012 HLA ABC m3, BB7.1 IgG2a, IgG1 Blue
119119
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Multicolor Combinations Catalog # Clone Isotype Excitation Laser
IgG1 FITC/IgG1 PE 70-IC5F5PE MCG1, MCG1 Blue
IgG1 FITC/IgG2a PE 70-IC5F6PE MCG1, MCG2a Blue
IgG1 FITC/IgG2b PE 70-IC5F7PE MCG1, MCG2b Blue
IgG2a FITC/IgG1 PE 70-IC6F5PE MCG2a, MCG1 Blue
IgG2a FITC/IgG2a PE 70-IC6F6PE MCG2a, MCG2a Blue
IgG2a FITC/IgG2b PE 70-IC6F7PE MCG2a, MCG2b Blue
IgG2b FITC/IgG1 PE 70-IC7F5PE MCG2b, MCG1 Blue
IgG2b FITC/IgG2a PE 70-IC7F6PE MCG2b, MCG2a Blue
IgG2b FITC/IgG2b PE 70-IC7F7PE MCG2b, MCG2b Blue
Kappa FITC/CD19 PE 70-KF2-19PE5 Blue
Kappa FITC/LAMBDA PE 70-KF2-LPE Blue
Lambda FITC/CD19 PE 70-LF-19PE5 Blue
LAMBDA FITC/Kappa PE 70-LF-KPE Blue
CD3 FITC/CD4 PE/CD8 PECy5 70-3F8-4PE9-8C2 Cris-7, Edu-2, B9.11 IgG2a, IgG2a, IgG1 Blue
CD3 FITC/CD4 PE/CD19 PECy5 70-3F8-4PE9-19C2 Cris-7, Edu-2, J4.119 IgG2a, IgG2a, IgG1 Blue
CD3 FITC/CD4 PE/CD45 PECy5 70-3F8-4PE9-45C3 Cris-7, Edu-2, IMMU19.2 IgG2a, IgG2a, IgG1 Blue
CD3 FITC/CD8 PE/CD19 PECy5 70-3F8-8PE4-19C2 Cris-7, 17D8, J4.119 IgG2a, IgG1, IgG1 Blue
CD3 FITC/CD8 PE/CD45 PECy5 70-3F8-8PE4-45C3 Cris-7, 17D8, IMMU19.2 IgG2a, IgG1, IgG1 Blue
CD3 FITC/CD16 PE/CD19 PECy5 70-3F8-16PE7-19C2 Cris-7, 3G8, J4.119 IgG2a, IgG1, IgG1 Blue
CD3 FITC/CD16+56 PE/CD19 PECy570-3F8-16PE7+56PE-19C2
Cris-7, 3G8+C5.9, J4.119 IgG2a, IgG1+IgG2b, IgG1 Blue
CD3 FITC/CD16+56 PE/CD45 PECy570-3F8-16PE7+56PE-45C3
Cris-7, 3G8+C5.9, IMMU19.2 IgG2a, IgG1+IgG2b, IgG1 Blue
CD3 FITC/CD19 PE/CD45 PECy5 70-3F8-19PE5-45C3 Cris-7, HD37, IMMU19.2 IgG2a, IgG1, IgG1 Blue
CD3 FITC/CD56 PE/CD19 PECy5 70-3F8-56PE-19C2 Cris-7, C5.9, J4.119 IgG2a, IgG2b, IgG1 Blue
CD4 FITC/CD8 PE/CD3 PECy5 70-4F6-8PE4-3C4 Edu-2, 17D8, UCHT1 IgG2a, IgG1, IgG1 Blue
CD4 FITC/CD8 PE/CD45 PECy5 70-4F6-8PE4-45C3 Edu-2, 17D8, IMMU19.2 IgG2a, IgG1, IgG1 Blue
CD8 FITC/CD4 PE/CD3 PECy5 70-8F8-4PE9-3C4 UCH-T4, Edu-2, UCHT1 IgG2a, IgG2a, IgG1 Blue
CD8 FITC/CD4 PE/CD19 PECy5 70-8F8-4PE9-19C2 UCH-T4, Edu-2, J4.119 IgG2a, IgG2a, IgG1 Blue
Immunology
120
Flow Cytometry
120
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Multicolor Combinations Catalog # Clone Isotype Excitation Laser
CD8 FITC/CD4 PE/CD45 PECy5 70-8F8-4PE9-45C3 UCH-T4, Edu-2, IMMU19.2 IgG2a, IgG2a, IgG1 Blue
CD10 FITC/CD5 PE/CD19 PECy5 70-10F1-5PE4-19C2 SN5c, MCD5, J4.119 IgG1, IgG2b, IgG1 Blue
CD16 FITC/CD19 PE/CD3 PECy5 70-16F6-19PE5-3C4 3G8, HD37, UCHT1 IgG1, IgG1, IgG1 Blue
CD56 FITC/CD19 PE/CD3 PECy5 70-56F-19PE5-3C4 C5.9, HD37, UCHT1 IgG2b, IgG1, IgG1 Blue
FMC7 FITC/CD23 PE/CD19PECy5 70-FMC7F-23PE3-19C2 FMC7, B-G6, J4.119 IgM, IgG1, IgG1 Blue
IgG1 FITC/IgG1 PE/IgG1 PECy5 70-IC5F5PE5C MCG1, MCG1, ZX3 Blue
IgG1 FITC/IgG2a PE/IgG1 PECy5 70-IC5F6PE5C MCG1, MCG2a, ZX3 Blue
IgG1 FITC/IgG2b PE/IgG1 PECy5 70-IC5F7PE5C MCG1, MCG2b, ZX3 Blue
IgG2a FITC/IgG1 PE/IgG1 PECy5 70-IC6F5PE5C MCG2a, MCG1, ZX3 Blue
IgG2a FITC/IgG2a PE/IgG1 PECy5 70-IC6F6PE5C MCG2a, MCG2a, ZX3 Blue
IgG2a FITC/IgG2b PE/IgG1 PECy5 70-IC6F7PE5C MCG2a, MCG2b, ZX3 Blue
IgG2b FITC/IgG1 PE/IgG1 PECy5 70-IC7F5PE5C MCG2b, MCG1, ZX3 Blue
IgG2b FITC/IgG2a PE/IgG1 PECy5 70-IC7F6PE5C MCG2b, MCG2a, ZX3 Blue
IgG2b FITC/IgG2b PE/IgG1 PECy5 70-IC7F7PE5C MCG2b, MCG2b, ZX3 Blue
Kappa FITC/Lambda PE/CD19 PECy5 70-KF2-LPE-19C2 Polyclonal, Polyclonal, J4.119 Polyclonal, Polyclonal, IgG1 Blue
Kappa FITC/Lambda PE/CD19 PECy5 70-KF2-LPE-19C2-50 Polyclonal, Polyclonal, J4.119 Polyclonal, Polyclonal, IgG1 Blue
Lambda FITC/Kappa PE/CD19 PECy5 70-LF-KPE-19C2 Polyclonal, Polyclonal, J4.119 Polyclonal, Polyclonal, IgG1 Blue
CD45 FITC/CD8 PE/CD4 PECy5/
CD3 APC 70-45F5-8PE4-4C3-3AP6 EO1, 17D8, 13B8.2, GA60 IgG2a, IgG1, IgG1, IgG1 Blue, Red
121121
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Product Catalog # Description
Studies of Major Lymphocyte Subpopulations (Two Color)
70-SPLC-25CD8 + SmIgλ-FITC CD56 + SmIgK-PE
Studies of Major Lymphocyte Subpopulations (Three Color)
70-SPLC4-25CD8 + SmIgλ-FITC CD56 + SmIgK-PE CD4-PerCP-Cy5.5
Product Catalog #
Basic Module Infinicyt™ 70-INFINICYT-P
Advanced Module Infinicyt™ 70-INFINICYT-ADV1
EuroFlow™ Validated Panels Infinicyt™ Data Analysis Software
Product Catalog # Description
Acute Leukemia Orientation Tube (ALOT-7) 70-ALOT77 conjugated antibodies designed for initial assessment of the nature of immature populations of hematopoietic cells in acute leukemia samples in order to allow appropriate orientation towards the complementary B, T lineage, and AML/MDS antibody panels.
Small Sample Screening Tube (SST) 70-SST10
11 conjugated antibodies designed for the detection of normal and aberrant lymphocyte populations of B, T and NK lineage by flow cytometry. This 8-color panel can be used for evaluation of “small” samples and samples with (very) low cell counts, such as fine needle aspirates (FNA), cerebrospinal fluid (CSF), vitreous humor, etc. with a suspicion of primary lymphoma.
Lymphoid Screening Tube (LST-11) 70-LST11
11 conjugated antibodies designed for the detection of aberrant mature lymphocyte populations of B, T and NK lineage by flow cytometry. This 8-color panel can be used for evaluation of several suspected conditions, such as lymphocytosis, lymph node enlargement, splenomegaly, monoclonal serum components, unexplained cytopenias, etc.
EuroFlow™ Validated Screening Tubes
Immunology
122
Flow Cytometry
122
Products are for Research Use Only unless otherwise noted ‡ Indicates an Analyte Specific Reagent
Type Description Catalog #
Equipment Quantum Blue® Lateral Flow Reader 02-BI-POCTR-ABS ^
Columns 11,12-DHET Immunoaffinity Columns 60-DH32
Columns Angiotensin II/Vasopressin Extraction Columns 02-A22/B-AEC
Columns Chromobond Columns 30-C-SE2112
Columns GLP-1 Sample Extraction Columns 43-GLPHU-SE50
Columns Melatonin Extraction Columns 02-MEL/B-MEC
Saliva Collection Salivettes (Sterile Saliva Collection Devices) 02-MEL/B-SVC
Saliva Collection SleepCheck Saliva Melatonin Collection Kit 01-B-SLEEPCHECK16
Stool Collection EasySampler® Stool Collection Kit 58-EZSAMPLER
Stool Collection Histamine ELISA Stool Collection Device 17-BA-D-1241
Stool Collection & Extraction ScheBo® Quick-Prep Fecal Sample Extraction Kit 02-B-CAL-SO50
Stool Collection & Extraction Smart-Prep Fecal Sample Extraction Kit 02-B-CAL-RD
Other Basiskit for LIA 14-HD-371.0
Other Care™ Fecal Occult Blood Rapid Testing Rack 43-FOBHU-RACK
Other Microplate Rotator (4 plate) 06-S2020-P4
Other Microplate Seal Film 06-SEAL-FILM
Other Non-Sterile Dispenser Syringe Tips 06-ST-3
Accessories & Equipment
125
Products are for Research Use Only unless otherwise noted * FDA Registered for In Vitro Diagnostic Use ^ Health Canada Licensed
5a-Androstane-3a, 17b-diol Glucuronide 48, 93
5-HIAA 93
6-Sulfatoxymelatonin 93
8-isoPGF2a 29
20-HETE 28
α-1-Acid Glycoprotein (AGP) 66, 100
α-1-Antichymotrypsin 48, 58
α-1-Microglobulin 100
α-2-Macroglobulin 100
α-Fodrin 58, 66
α-MSH 48, 93
ß-2 Microglobulin 101
ß-4 Thymosin 87
ß-Catenin 66, 76
ß hCG 48
A
A Proliferation Inducing Ligand (APRIL) 71
Acid Labile Subunit 48
AcSDKP 29
Adenosine 29
Adenovirus 6
Adipocyte Fatty Acid Binding Protein 38
ADH 35, 54
ADH/AVP 35, 54
Adiponectin 38, 42
ADMA 29, 30
Adrenocorticotropic Hormone (ACTH) 29, 48, 93
AKT1/2 66
Albumin 39, 100, 101
Aldosterone 28, 34, 48
Alpha-1 Thymosin 59
Alpha-Fetoprotein (AFP) 48, 101
Alpha-Lactalbumin 66
Amanitin 101
ANA 66, 75
Androstenedione 48
Angiotensin 28, 30, 34, 48, 125
Angiotensin Converting Enzyme (ACE) 28, 29, 48, 66
Annexin V 66
ANP 29, 30, 100, 101
Anti-ANCA 66
Anti-BPI 66
Anti-Cag-A 6
Anti-Candida 6
Anti-Cardiolipin 67
Anti-Casein 6, 59, 67
Anti-CaSR 67
Anti-CCP (CCPlus Immunoscan®) 72, 73
Anti-CENP-B 67
Anti-Cytomegalovirus 6, 7, 67
Anti-ds-DNA 67
Anti-Elastase 67
Anti-Gliadin 7, 59, 67
Anti-GM1 Autoantibodies 93
Anti-Helicobacter Pylori 7, 8, 59, 60, 68
Anti-Histone 68
Anti-IFN ß 68, 93
Anti-Inositol-GM 68
Anti-Insulin Autoantibodies (AIA) 39, 40, 66, 68, 81
Anti-Intrinsic Factor 68
Anti-Jo-1 69
Anti-LC1 69
Anti-LKM-1 69
Anti-M2 69
Anti-MAG 69, 93
Anti-Ovalbumin 8, 60, 69
Anti-Ovarian Antibody 69
Antioxidative Capacity 30
Anti-Phosphatidyl-Serine 69
Anti-Phospholipid-8 69
Anti-Prothrombin 69
Anti-Rheumatoid Factor (RF) 69
Anti-Ps-Aeruginosa 8
Anti-Ribosomal P 69
Anti-Rubella 8, 69
Anti-Saccharomyces Cerevisiae (Crohns Check) 61, 75
Anti-Scl 70 70
Anti-SGPG 70, 92, 93
Anti-SLA 70
Anti-Sm 70
Anti-Soya 8, 60, 70
Anti-Sperm Antibody 48, 70
Anti-SS 70
Anti-ß 2 Glycoprotein 70
Anti-ss-DNA ELISA 70
Anti-ß Lactoglobulin 70
126
IndexIndex
Antithrombin 30, 70
Anti-Thyroid Peroxidase Antibody (TPO) 49, 54
Anti-U1-70 71
AOPP 30
Apolipoprotein 30
ASCA 66, 71
Aspergillus 8, 17, 71
AVP 35, 54
B
BAFF 71
Basophil Activation (FlowCAST®) 10, 61
Bcl-2 71
Biotin 60, 109, 110, 111, 112, 113, 115, 116, 117, 118
Blastocystis Antigen 71
BNP 29, 30, 100, 102
Bone Sialoprotein 22
Bordetella Pertussis 8, 71
Bradykinin 30, 94
Brucella 8
C
C4a 71
C5a 71
Calcitonin 22, 49
Calcitonin Gene Related Peptide (CGRP) 94
Calprotectin 57, 58, 60, 71, 72
cAMP 94
Cancer Antigen 72, 73
Carbonylated Protein 31
Cardiolipin 67, 73
Cartilage Oligomeric Matrix Proetin (Hcomp) 23
Casomorphin 8, 60
Caspase 73, 118
Cathepsin 22, 67, 73
CD153 73
CEA 73
Cell Adhesion Molecule (L1-CAM) 82
Cell Proliferation & Toxicity 74
Cellular Adhesion Molecule (sICAM-2) 87
Cellular Adhesion Molecule (sICAM-3) 87
Cellular Adhesion Molecule (sVCAM-1) 88
Ceruloplasmin 31
CETP 31
cGMP 94
Chemerin 74
Chlamydia 6, 9, 74
Cholecystokinin (CCK) 39, 49
Chromogranin A 49, 94
Chrorionic Gonadotropin (hCG) 48, 50
Chymotrypsin 61, 74
Ciculating Immune Complex (C1q) 67, 74
CINC-1 74
Citrullinated Protein Antibodies (CPA) 75, 118
Clusterin 100, 102
c-Met 49
Complement Factor 3 74
Complement System 74, 75
Connective Tissue Factor (CTGF) 23, 75
Corticosterone 49
Corticotropin Releasing Factor (CRF) 31, 94
Cortisol 49
C-Peptide 39
C-Reactive Protein (CRP) 74, 75
Creatine Kinase ELISA 31, 102
CREB ELISA 75
Cripto-1 75
CRP 31, 74, 75
C. Trachomatis 8, 71
Cu/ZnSOD 75
Cystatin C 100, 102
Cytochrome C 75
Cytokeratin Fragment (CYFRA) 75
D
DAO 9, 31, 61
Dengue 9, 75
Deoxypyridinoline (DPD) 23
DHEA 49
DHET 28, 125
DHT 49
DKK-1 23
Dopamine 94, 96, 97
127
E
Echinococcus Granulosus 9
Endostatin 31, 102
Endothelin 31
Eosinophil Derived Neurotoxin (EDN) 61
Eotaxin 76
Epidermal Growth Factor (EGF) 76
Epinephrine 93, 94, 96, 97
Epstein Barr Virus 9
ERK1/2 76
Erythropoietin (EPO) 31, 49
Estradiol 48, 49
Estriol 49
Estrone 49
F
Fasciola Hepatica 9
Ferritin 31, 49
Fetuin-A 23, 31
FGF 39, 50, 76
FGF-21 39, 76
Fibrinogen 31, 32
Fibronectin 32
Folicle Stimulating Hormone (FSH) 50
G
GABA 94
GAD 39, 76
Galectin-3 32, 76
GanglioCombi® Anti-Ganglioside 76, 94
Gastrin RIA 39, 61
G-CSF 76
GFAP 94
GHB 96, 102
Ghrelin 38, 39
Gliadorphin 61
Glicentin 39
Glomerular Basement Membrance (GBM) 30, 67
GLP-1 39, 41, 125
GLP-2 40
Glucagon 40, 41
Glutamate 16, 96
Glutathione 32, 40, 50
GM-CSF 76
GPx Activity 32
Granzyme 76
Growth Hormone 50, 51
GSK3α/ß 66, 76
GST 32, 99, 100, 101, 102, 103, 118
H
Haptoglobin 32, 61, 76, 77, 102
HAV 7, 67, 68
HBc 68
HBs 68
HBsAg 77
HCV 7, 68
Hemoglobin 32, 61
Hemopexin 33
Hepcidin 33, 50, 51
HER-2 77
Herpes 8, 10, 68, 77
Histamine 10, 77, 125
Homocysteine 33, 51
Human Anti-Human Antibody (HAHA) 76
Human Placental Lactogen (HPL) 51
Hydroxy Pyridinium Crosslinks (PYD/DPD) 23
I
IFN-gamma 77
IgA 6, 7, 8, 9, 10, 11, 12, 58, 59, 60, 61, 62, 66, 67, 68, 69,
70, 71, 73, 74, 75, 77, 78, 86
IgD 78
IgE 5, 6, 7, 78
IGF-1 50, 51
IGF-2 52
IGFBP-1 52
IGFBP-2 51, 52
IGFBP-3 51, 52
IgG 6, 7, 8, 9, 10, 11, 12, 39, 58, 59, 60, 61, 66, 67, 68,
69, 70, 71, 72, 73, 74, 75, 78, 81, 82, 83, 84, 86, 89, 91,
95, 118
IgG1 78, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117,
118, 119, 120, 121
IgG2A 78
IgG2B 78
IgG3 78
128
Index
IgM 6, 7, 8, 9, 10, 11, 12, 60, 67, 68, 69, 70, 73, 74, 75, 77,
78, 82, 83, 89, 91, 92, 93, 95, 115, 121
IgY 78
IL-1RA 80
IL-1ß 40, 80
IL-1α 80
IL-2 80
IL-3 80
IL-4 81
IL-5 81
IL-6 23, 24, 40, 81
IL-8 40, 81
IL-9 81
IL-10 78, 79
IL-12 79
IL-13 ELISA 79
IL-15 79
IL-17A 79
IL-17AF 79
IL-17F 79
IL-18 79
IL-21 80
IL-22 80
IL-23 79, 80
IL-27 80
IL-29 80
IL-31 80
IL-33 81
Influenza 10
Insulin 39, 40, 41, 42, 44, 50, 51, 68, 81
IP-10 81
Islet Cell Antibody 42, 81
J
Japanese Encephalitis 10, 81, 82
K
Kappa 82, 119, 120, 121
KIM-1 100, 102
Krytopyrrole 33
L
Lactoferrin 61, 82
Lambda 82, 119, 120, 121
L-Citrulline 82
Lecithin-Cholesterol Acyltransferase (LCAT) 33
Leptin 42
Leukemia Inhbitory Factor 82
Leukotriene Function (CAST®) 8, 9, 60, 61
L-FABP 102
Lipoprotein 33
LPL 33
Luteinizing Hormone 52
Lysozyme 61, 62
M
Malondialdehyde 33
Matrix Metalloproteinase (MMP) 82
MCP-1 42, 82
Measles 10, 82
Melatonin 96, 97, 125
Metanephrine 94, 96
Microalbumin 42, 102
MPO ELISA 33, 69, 82
MRP 8/14 ELISA 33, 62, 82
Mumps 11
Mycobacterium Tuberculosis 11, 82
Mycoplasma Hominis 11
Myoglobin 33, 103
Myostatin 24, 43, 52
N
NAG 103
Neopterin 82, 83
Neuron Specific Enolase (NSE) 96
Neuropeptide Y (NPY) 43, 96
NGAL 43, 82, 83, 99, 103
Nitric Oxide Synthase 1 (NOS1) 33
Nitrotyrosine 33
Norepinephrine 93, 94, 96, 97
Normetanephrine 94
Nt-proCNP 24, 33
Nucleo-h 83
O
Obestatin 43
Orientia Tsutsugamushi 11, 83
129
Osteocalcin 24
Osteopontin 24, 84, 103
Osteoprotegerin 24, 33
Ovotransferrin 84
Oxidized LDL 34
OxyStat 34
P
p38 α 84
p53 84
PAI-1 43, 84
Pancreatic Amylase 43
Pancreatic Polypeptide 43
PAP Complex 84
PAPP-A 52, 84
Parvovirus B 19 11
Pepsinogen 43, 62
Pertussis 8, 71, 84
Phospholipase 2 34
Plasminogen 34
Platelet Derived Growth Factor 84
PMN Elastase 84
Porphyrins 84
PR3 ANCA 69
Prealbumin 52, 103
Pregnant Mare Serum Gonadotropin (PMSG) 52
Pregnenolone 52
Procollagen III Peptide 24, 104
Progesterone 48, 52, 53
Progranulin 84
Proinsulin ELISA 43
Prolactin 53
PSA 53, 84, 96
PYY 43, 96
R
RANTES/CCL5 84
RBP 43
RC4d 84, 85
Relaxin 53
Renin 28, 34, 35, 48, 53
Resistin 44
Respiratory Syncytial Virus 11
S
s90K/Mac-2BP 84
S100A12 62
S100 ß 96
sAPO-1/Fas 84
sCD23 85
sCD26 85
sCD28 85
sCD30 85
sCD40 85
sCD40L 85
sCD44std 86
sCD44var 86
sCD134 84
sCD137 84
sCD152/CTLA-4 85
Sclero-Profile 86
Sclerostin 22, 23, 24, 25, 44
Secretory IgA 62, 86
SeroMP 86
Serotonin 96
Serum Amyloid 35, 44, 86, 96
sE-selectin 86
sFas Ligand 86
SHBG 53
sICAM-1 86, 87
sL-selectin 87
Somatostatin 44, 53
sPECAM-1 87
sP-selectin 87
sPSGL-1 87
sRANKL 25
STELLUX™ 38, 41, 44
sTNF-R 87
sVE-cadherin 88
Syphilis 11
T
T4 17, 53, 119, 120, 121
TBG 54
Testosterone 54
Tetanus Toxin 11
Thyroglobulin (TG) 48, 54
130
Index
TGF ß-1 88
TGF ß-2 88
Thiostatin 88
Thymulin 88
TIE-2 88
TIMP-1 88
Tissue Transglutaminase 60, 61, 67, 71, 74
TNF Related Apoptosis Inducing Ligand (TRAIL) 89
TNF-ß 88
TNF-α 44, 45, 88, 89
Toxoplasma 11
Transferrin 35
Triiodothyronine (T3) 17, 53
Troponin I 35, 100, 101
Tryptophan 97
TSH 54
Type IV Collagen 104
U
Ubiquinone Coenzyme Q10 35
Ureaplasma Urealyticum 12
Urocortin 97
Urotensin II 35
V
Varicella Zoster 12
Vascular Adhesion Protein (sVAP-1) 87
Vascular Endothelial Growth Factor (VEGF) 89
Vasoactive Intestinal Peptide 54, 63
Vasopressin (ADH/AVP) 35, 54, 125
Vaspin 45
Visceral Leishmaniasis 12, 89
Vitamin A 35, 63
Vitamin B1 62, 63
Vitamin B2 62
Vitamin B3 62
Vitamin B5 63
Vitamin B6 35, 63
Vitamin B9 61
Vitamin B12 63
Vitamin C 63
Vitamin D 22, 25, 48, 58, 63, 100, 104
Vitamin E 35, 63
Vitamin K1 25, 63
W
West Nile Virus 9, 12, 89
Z
Zonulin 63, 89
131
Ordering Online
Please visit our website at www.alpco.com to set up
an account and place an online order. ALPCO accepts
MasterCard, Visa and American Express. If you choose
to set up an online account and want Terms, you will
be contacted by a Customer Service Associate upon
placing your first order to complete a credit application.
Establishing a new customer account
To establish a new customer account with Terms,
contact Customer Service to obtain a credit application.
Completed applications can be emailed to cs@alpco.
com or faxed to (603)898-6854. Upon acceptance of
a completed credit application, you will be provided
with an 8 character Customer I.D. number, (i.e.
ALPCO=ALPCO001) for ordering purposes.
Orders by Fax
Faxed orders can be sent to (603)898-6854. Be
sure to include your Customer I.D. number, special
instructions and price quotation when applicable to
ensure proper pricing.
Orders by Phone
To order by phone, simply supply our Customer
Service staff with your ALPCO customer ID number,
a valid purchase order number or valid credit card, the
appropriate catalog numbers and the required quantities.
Iodination Dates
ALPCO has developed a schedule of iodination dates for
all radio-labeled assay kits to ensure that customers can
receive the freshest kits possible. This allows ALPCO
customers to effectively plan their usage. Contact ALPCO
Customer Service at [email protected] or call (800)592-
5726 to obtain iodination schedule information.
Call today for more information or to place an order by phone. You can also submit
online orders by visiting www.alpco.com.
132
IndexOrdering Information
Licensing and Warranty
In compliance with US Federal regulations, all
customers ordering radioactive products must submit a
copy of the institution’s most current and valid radiation
license to ALPCO. This documentation will remain on
file for future ordering.
All products manufactured and/or distributed by
ALPCO should be used in accordance with the
labeled intended use. All products that are labeled
“For Research Use Only. Not for Use in Diagnostic
Procedures.” are supplied for research applications and
not for use in diagnostic or clinical use. Please contact
ALPCO for current product status.
ALPCO, it’s manufacturers and/or distributors make no
warranties either expressed or implied concerning any
matter whatsoever, including without limitations, the
condition of the product, its merchantability, or its fitness
for any particular use. Any modification of a test as well
as exchange or mixture of any components from different
lots may influence results, and cannot be supported.
Terms of Sale
Terms of Sale are net 30 days from date of invoice. Report
all incidents of shortage, breakage or any product damage
within 5 days of receipt of goods to ALPCO at www.alpco.
com, through our Resources/Contact Us feature or calling
(800) 592-5726. Should damage occur during shipping,
please report damages to both the carrier and ALPCO.
ALPCO assumes no liability for loss or delay caused by
conditions beyond ALPCO’s control. Report all shipping
errors to ALPCO immediately. Due to the nature of the
products listed herein, all sales are considered final. No
consideration will be given to returns or replacements
unless prior authorization and shipping instructions have
been obtained from ALPCO Customer Service.
Shipping
Shipping and handling charges are (FOB/EXW: Salem,
NH 03079)and prepaid and added to your invoice
total. ALPCO uses standard overnight service on most
domestic shipments.
Information on hot deal discounts, new product promotions, and special offers can
be found on the Promotions section of the ALPCO website. Order soon because
supplies are limited!
133
ALPCO
26-G Keewaydin Drive
Salem, NH 03079
Phone: 800-592-5726
Fax: 603-898-6854
www.alpco.com
2013–2014