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    BIT INTERNATIONAL COLLEGECOLLEGE OF NURSING

    Gastric Mucosa Erosion

    A case presentation

    Presented to the faculty of the BITINTERNATIONAL COLLEGE - College of Nursing

    Presented by:JOHN MICHAEL PITOYGERALDINE LUCIP

    GREMARIE ARADOGRETCHEN ELIZABETH IMBATJEFREY CALAPINE

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    INTRODUCTION

    Abdominal trauma is any event which causes serious injury to the abdomen. The trauma may be so significant that

    multiple abdominal organs may be damaged. Most abdominal traumas are categorized as being either a penetrating or blunt

    injury. In any event, this is a very serious situation and the person who has suffered the trauma should get medical attention as

    soon as possible. There are many ways a person may suffer an abdominal injury, with some of the most common ways being an

    accident or an assault.

    EPIDEMIOLOGY

    The abdomen is the third most commonly injured region of the body and the trauma of the abdomen occurs in 20% of the

    civilian injuries requiring surgical intervention. In the urban trauma center approximately the 25% of the injury are represented

    by the stab wounds (in the USA trauma center 35% gunshot wounds) and 10% are the blunt abdominal trauma. In the rural

    area the percentage shows a 17% of stab wounds, 14% gunshot and the remaining lesions are due to the blunt trauma. A large

    part of the blunt abdominal trauma (some series report 60%) are caused by motor vehicle accident; in the last few years the use

    of the life-belt has leads to a prevention of such lesions.

    http://www.wisegeek.com/what-is-a-trauma.htmhttp://www.wisegeek.com/what-is-the-abdomen.htmhttp://www.wisegeek.com/what-are-abdominal-organs.htmhttp://www.wisegeek.com/what-are-abdominal-organs.htmhttp://www.wisegeek.com/what-is-the-abdomen.htmhttp://www.wisegeek.com/what-is-a-trauma.htm
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    RATIONALE

    The Level III Student-Nurses of the BIT- International College, College of Nursing are conducting this case study directed for

    better understanding of the nature and pathophysiology and to apply theoretical knowledge in handling patients with Abdominal

    trauma secondary to perforated hollow viscus.

    The study was achieved thru the exposure of Level-III Student-Nurses at Governor Celestino Gallares Memorial Hospital,

    Operating Room at City of Tagbilaran, Bohol.

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    I. ASSESSMENT

    A. Data BasePatients Initials : L.C.B.

    Age : 51 years old

    Sex : Male

    Status : Single

    Religion : Roman-Catholic

    Address : Calayugan Norte, Loon, Bohol 6327

    Admitting Doctor : Dr. Florence Cepedoza

    Admitting Diagnosis : Acute Abdominal Problem Secondary to Perforated Hollow Viscus

    Admission Date : May 21, 2011

    Admission Time : 10:15 p.m.

    Hospital : Governor Celestino Gallares Memorial Hospital, Tagbilaran City, Bohol, Philippines

    B. Social History

    Patient L.B. describes himself as loving father of two, friendly and has circle of associates at his town. He loves to drink

    native wine with his neighbors and associates. He also mentioned of being active in the church activities and gatherings during

    Sundays.

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    C. Chief ComplaintsAbdominal pain

    D. History of Present IllnessPatient L.B. has been having on and off epigastric pain. Six (6) weeks prior to admission (PTA), Patient L.B. had

    resumed epigastric pain also with vomiting.

    E. Family HistoryHPN (+) DM (-)UTI (+) HPB(-)

    F. Food AllergiesPatient mentioned of no known allergies to any foods or drugs.

    G. Condition on AdmissionBlood Pressure : 140/90 mmHg

    Pulse Rate : 82 bpm

    Respiratory Rate : 24 cpm

    Temperature : 37.3 C

    H.Admitting/Current/Ruled-in Medical DiagnosisAcute Abdominal Problem Secondary to Perforated Hollow Viscus

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    II. LABORATORY AND DIAGNOSTIC RESULTS05/22/11

    COMPLETE BLOOD COUNT

    Name of lab./ Diagnostic

    exam

    Patients Results Normal values Significance

    WBC- White blood cell 8.1 K/uL 4.0-11.0

    RBC- Red Blood Cell 2.85 L M/uL 4.50-6.50 Decreased in Red Blood Cell

    indicates bleeding, anemia.

    Hgb-Hemoglobin 8.5 L g/dL 13.0-18.0 Decreased Hemoglobin

    indicates depleted blood

    oxygen-carrying capability.

    Hct- Hematocrit 26.3 L % 40.0-54.0 Decreased in Hematocrit

    indicates anemia.

    MCV- Mean Corpuscular

    Volume

    92 fL 76-96

    MCH- Mean Corpuscular 29.6 Pg 26.0-32.0

    MCHC- Mean Corpuscular 32.2 g/dL 30.0-35.0

    RDW 13.6 % 11.5-14.5

    Plt- Platelet Count 376 k/uL 150-400

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    05/22/11

    DIFERENTIAL COUNT

    Name of lab./ Diagnostic

    exam

    Patients Results Normal values Significance

    Neutrophil 79 H 40-75 Increased level of neutrophil

    count indicates stress.

    Lymphocyte 11 L 20-45 Decreased level of lymphocyte

    count indicates infection

    especially H- pylori.

    Monocyte 6 0-10

    Eosinophil 4 0-6

    Basophil 0 0-1

    CHEMISTRY

    Name of lab./ Diagnostic

    exam

    Patients Results Normal values Significance

    Sodium 134.2 mmol/L 135-155

    Potassium 3.15 mmol/L 3.6-5.5

    Creatinine 378.4 mmol/L 53-97 Increased level of creatinine

    count indicates increased level

    in blood pressure, and or the

    body declines to function

    properly especially the

    kidneys.

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    III. ANATOMY AND PHYSIOLOGY:An organ with an abnormal opening often is referred to as a perforated viscus. Viscus technically means a hollow organ

    found inside the body. The term viscus is a singular form, often used in referring to only one organ involved. Its plural

    term, viscera, generally is used to denote the involvement of many organs. Hollow organs often have several layers of cells in

    their walls in order to hold materials inside. A hollow viscus perforation can occur in many instances. Blunt

    abdominal trauma such as those that often happen in road accidents can lead to the perforation of the spleen and other organs.

    Penetrating abdominal trauma often can reach important organs like the intestines and stomach as seen in those caused bygunshots and stab wounds. Infections sometimes can lead to viscus perforation such as those that occur in a ruptured appendix,

    ruptured gallbladder, and as a complication of typhoid fever.

    Perforated viscus symptoms generally range from moderate to severe manifestations. They mostly include fever, low

    blood pressure, fast heart rate, abdominal pain, nausea, vomiting, and abdominal distention. Patients mostly are in severe pain

    with their abdomen feeling rigid or board-like when touched. When prompt treatment for a perforated viscus is not given,

    patients often develop complications that can be life-threatening. Open surgery generally is the standard management for a

    perforated viscus. Exploratory laparotomy was performed and it revealed a gastric mucosa erosion thus, surgeon decided to do

    vagotomy.

    http://www.wisegeek.com/what-is-a-viscus.htmhttp://www.wisegeek.com/what-is-the-viscera.htmhttp://www.wisegeek.com/what-is-a-trauma.htmhttp://www.wisegeek.com/what-is-a-ruptured-aneurysm.htmhttp://www.wisegeek.com/what-causes-vomiting.htmhttp://www.wisegeek.com/what-causes-vomiting.htmhttp://www.wisegeek.com/what-is-a-ruptured-aneurysm.htmhttp://www.wisegeek.com/what-is-a-trauma.htmhttp://www.wisegeek.com/what-is-the-viscera.htmhttp://www.wisegeek.com/what-is-a-viscus.htm
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    IV-A PATHOPHYSIOLOGY

    The most common cause of this form of gastric mucosa erosion is the use of NSAIDs. Other causes may be alcoholism orstress from surgery or critical illness. The role of NSAIDs in development of gastritis and peptic ulcers depends on the dose level.

    Although even low doses of aspirin or other non-steroidal anti-inflammatory drugs may cause some gastric upset, low dosesgenerally will not lead to gastritis. However, as many as 1030% of patients on higher and more frequent doses of NSAIDs, suchas those with chronic arthritis, may develop gastric ulcers. Patients with H. pylorialready present in the stomach who are treatedwith NSAIDs are much more susceptible to ulcers and other gastrointestinal effects of these pain killers.

    Patients with erosive gastritis may also show no symptoms. When symptoms do occur, they may include anorexia nervosa,gastric pain, nausea, and vomiting.

    Gastric Erosion is a minor ulceration of the gastric mucosa. A localized inflammation or minor ulceration of the stomachlining. Gastric erosion is a slight break (or "ulceration") in the innermost layer (called "mucosa") of the stomach's lining. If anulceration extends deeper than this layer, it is called a gastric ulcer. Gastrosplenic fistula resulting from erosion of a primarysplenic lymphoma is a rare cause of massive upper gastrointestinal hemorrhage associated with benign peptic ulcer disease,gastric Crohn's disease, gastric adenocarcinoma, and primary gastric and splenic lymphomas. It is concluded from these resultsthat IL-1 acts mainly in the central nervous system to inhibit the occurrence ofstress-induced gastric erosion and that the IL-1

    beta-induced inhibition of gastric erosion is mediated by prostaglandin in a manner that is independent of brain CRF. See alsoduodenal ulcer , which is a break in the normal tissue lining the duodenum (the first part of the small bowel).

    The common Causes of Gastric Erosion :

    Drugs like aspirin and steroid. cortisone drugs (steroids) used to treat asthma, Addison's disease or other conditions;

    Benign gastric ulcers are caused by an imbalance between the secretion of acid and an enzyme called pepsin and thedefenses of the stomach mucosal lining. This leads to inflammation and may be precipitated by aspirin and nonsteroidal anti-inflammatory medications (NSAIDs)

    such as ibruprofen.

    http://www.healthline.com/adamcontent/alcoholismhttp://www.healthline.com/goldcontent/aspirinhttp://www.healthline.com/galecontent/nonsteroidal-anti-inflammatory-drugs-2http://www.healthline.com/adamcontent/anorexia-nervosahttp://www.health-disease.org/digestive-disorders/gastric-erosion.htmhttp://www.health-disease.org/digestive-disorders/gastric-erosion.htmhttp://www.health-disease.org/digestive-disorders/gastric-erosion.htmhttp://www.health-disease.org/digestive-disorders/gastric-erosion.htmhttp://www.health-disease.org/digestive-disorders/gastric-erosion.htmhttp://www.health-disease.org/digestive-disorders/gastric-erosion.htmhttp://www.health-disease.org/digestive-disorders/gastric-erosion.htmhttp://www.health-disease.org/digestive-disorders/gastric-erosion.htmhttp://www.healthline.com/adamcontent/anorexia-nervosahttp://www.healthline.com/galecontent/nonsteroidal-anti-inflammatory-drugs-2http://www.healthline.com/goldcontent/aspirinhttp://www.healthline.com/adamcontent/alcoholism
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    Symptoms of Gastric Erosion

    Stomach bleeding Blood in stools or black, tarry stools Anemia Weight loss Fatigue Black stool Nasea Abdominal indigestion Blood in stools or black, tarry stools

    Treatment of Gastric Erosion

    Multiple regimens are effective and usually include either an H2 receptor antagonist such as famotidine (Pepcid) ornizatidine (Axid) or a proton pump inhibitor such as omeprazole (Prilosec) or esomeprazole (Nexium) to suppress acid,combined with two antibiotics.

    Surgical intervention may be recommended for people who do not respond to medical therapy or to endoscopic therapyfor bleeding.

    However, combined treatment with estrogen and lithium, significantly decreased the severity of gastric erosions in intactbut not in ovariectomized rats and this was associated with a significant increase in the endogenous histamine content ofthe gastric mucosa.

    Avoiding smoking Avoiding tea, coffee , and soft drinks containing caffeine

    http://www.health-disease.org/digestive-disorders/gastric-erosion.htmhttp://www.health-disease.org/digestive-disorders/gastric-erosion.htm
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    ILLUSTRATION

    Illustration of the abdomen

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    IV-B PATHOPHYSIOLOGY:

    Gastric mucosal erosion-is a

    minor ulceration of the gastric

    mucosa, brought by an abdominal

    trauma or problems, and orhollow viscus.

    CAUSE

    H. pyloriAlcoholism

    SYMPTOMS

    Stomach bleeding Blood in stools or

    black, tarry stoolsAnemia Weight loss Fatigue Black stool NauseaAbdominal indigestion Blood in stools or

    black, tarry stools

    TREATMENT

    Multiple regimens are effective and usually include either an H2receptor antagonist such as famotidine (Pepcid) or nizatidine(Axid) or a proton pump inhibitor such as omeprazole (Prilosec) oresomeprazole (Nexium) to suppress acid, combined with twoantibiotics.

    Surgical intervention may be recommended for people who do notrespond to medical therapy or to endoscopic therapy for bleeding.

    DIAGNOSIS

    Laboratory studies of blood testfor anemia X-rays of the upper digestive

    tract

    COMPLICATIONS

    BleedingAnemia

    PREVENTION

    Avoiding smoking Avoiding tea, coffee , and soft drinks containing caffeine

    http://www.healthline.com/adamcontent/alcoholismhttp://www.health-disease.org/digestive-disorders/gastric-erosion.htmhttp://www.health-disease.org/digestive-disorders/gastric-erosion.htmhttp://www.healthline.com/adamcontent/alcoholism
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    Avoiding smokingAvoiding tea, coffee , and soft drinks containing caffeine