Carol Friedman, D.O.

Associate Director for Adult Immunization

Immunization Services Division

National Center for Immunization and Respiratory Diseases

Centers for Disease Control and Prevention

Seasonal Flu Vaccine Update2009-2010

Seasonal Flu Vaccine Supply

• June 2009 vaccine manufacturers state 118 million doses of seasonal flu vaccine will be produced

• August 2009 numbers revised to 114 million doses produced

• Represents ~3% reduction from original projection

• Amount of vaccine distributed similar to 2008-2009 flu season

U.S. Seasonal Influenza Vaccine: Production and Use

Doses Produced (millions)

Doses Distributed (millions)

2006 120.9 102.5

2007 140.6 112.8

2008 135.9 113

2009 114 (est) 112.7*

*Amount reported by manufacturers to CDC which is being validated.

Vaccine Supply Challenges

• Vaccine available much earlier

• Increased demand

• Facilities switched to production of H1N1 vaccine production

• Delay in availability of vaccine

• Pre-booked orders canceled or reduced

0.0

0.5

1.0

1.5

2.0

2.5

7-Aug 21-Aug 4-Sep 18-Sep 2-Oct 16-Oct 30-Oct 13-Nov 27-Nov 11-Dec 25-Dec 8-Jan

Mill

ion

s

Week of Incidence

2004 2005 2006

2007 2008 2009

# o

f Vac

cin

atio

ns

Weekly Flu Vaccinations in Medicare Population in 2009 Compared to 2004-2008Measurement Criteria: Procedure on Any Claim Processed as of Week 2 in Jan10

Long-Term Care Facilities (LTCF) Affected

• Reports of vaccine shortages among LTCFs– Orders canceled or reduced

• Additional 500,000 doses made available for LTCF in December

• Pharmacies, supermarkets, community vaccinators provided vaccine

0

10

20

30

40

50

60

70

80

90

100

7-Aug 21-Aug 4-Sep 18-Sep 2-Oct 16-Oct 30-Oct 13-Nov 27-Nov 11-Dec 25-Dec 8-Jan

Week of Incidence

2006 2007 2008 2009

Rate

of V

accin

atio

ns (p

er

1,0

00)

Weekly Flu Vaccination Rate in 2009 Compared to 2006-2008Measurement Criteria: Procedure on Any Claim Processed as of Week 2 in Jan10

Population: Part D Medicare Institutionalized

Demand Remains High

• Cumulative seasonal influenza vaccination coverage since August was 42% by Jan 2

• Demand for seasonal vaccine remains higher than supply (139-173 million vs. 114 available)– Majority of people report they have gotten, will

definitely get, or will probably get seasonal flu vaccine (58%)

Outlook for Next Season

• ACIP Influenza Work Group considering universal flu recommendation

– Begin 2010-2011

– Two stage

• Encourage for 2010-2011

• Full implementation 2011-2012

• Fluzone High Dose Vaccine

– High-dose seasonal flu vaccine for persons ≥65 years

– Contains 4 x amount of antigen

– FDA licensed December

Outlook for Next Season (2)

• Preliminary reports indicate manufacturers plan to make at least as much vaccine as this year

– Will this be enough?

• Vaccine composition

– Strains will be identified at VRBPAC* meeting in February

– Likely include 2009 H1N1 strain

*Vaccines and Related Biological Products Advisory Committee

Thank You!!

Questions??