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Normal Cell Normal levels of Glucose, Triglycerides and Glutamine taken up for energy, as a resource for building new cells and general maintenance Oxidative Phosphorylation is the normal method of utilising energy from glucose

CANCER-BIOLOGY for weebsite - Care Oncology Clinic · Microsoft PowerPoint - CANCER-BIOLOGY for weebsite Author: Suzanne.Dilly Created Date: 4/24/2014 5:12:34 PM

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Page 1: CANCER-BIOLOGY for weebsite - Care Oncology Clinic · Microsoft PowerPoint - CANCER-BIOLOGY for weebsite Author: Suzanne.Dilly Created Date: 4/24/2014 5:12:34 PM

Normal

Cell

• Normal levels of

Glucose,

Triglycerides and

Glutamine taken up

for energy, as a

resource for

building new cells

and general

maintenance

• Oxidative

Phosphorylation is

the normal method

of utilising energy

from glucose

Page 2: CANCER-BIOLOGY for weebsite - Care Oncology Clinic · Microsoft PowerPoint - CANCER-BIOLOGY for weebsite Author: Suzanne.Dilly Created Date: 4/24/2014 5:12:34 PM

Cancerous

Cell

• Oxidative

Phosphorylation

switched off – cell

makes major

adjustments to

compensate

• Extra glucose is

gained by using less

specific glucose

receptor (GLUT1)

• Extra uptake of

Glutamine and

Triglycerides • Cancerous cells divert normal nutritional

supplies towards cancerous growth (shown

here as green stars)

Page 3: CANCER-BIOLOGY for weebsite - Care Oncology Clinic · Microsoft PowerPoint - CANCER-BIOLOGY for weebsite Author: Suzanne.Dilly Created Date: 4/24/2014 5:12:34 PM

Treatment

for Cancer

Cell

• Drugs highlighted

with actions known

from prior clinical

usages

• Your treatment may

contain some or all of

these, or similar

drugs from the same

categories

Inappropriate Cancerous Growth –

blocking the nutrient supply along the green

lines will help starve the cancerous growth

Page 4: CANCER-BIOLOGY for weebsite - Care Oncology Clinic · Microsoft PowerPoint - CANCER-BIOLOGY for weebsite Author: Suzanne.Dilly Created Date: 4/24/2014 5:12:34 PM

Technical

Diagram