Call 4 eHealth activities until FP7 · monitoring systems) and more about optimal utilization of existing relevant information resources (data, signals, knowledge) Scope of Call 4

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Paris, 13/1/2005

Call 4eHealth activities until FP7

Gérard ComynHead of UnitDG INFSO/C4 (ICT for Health)

PASTPAST 10 years (1991-2002)

FP2 FP3 FP4 FP5

Computer Applications for

DoctorsTelemedicine systems

and services

Budget

20M €Budget

100M €Budget

140M €Budget

200M €

Projects

30Projects

63Projects

158Projects

125Results

Feasibility Study

ResultsAIM

Community

Results1st batch of Products

ResultsEU Health TelematicsIndustry

20 Years of eHealth R&D Context

Regional Health Info Networks

Home-care systems

Personal Health Systems

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Region 2Region 3

Hospital

Home

Pharmacy

Health Center

A80218-Siemens© GThttp://www-GT.med.siemens.de

mobile PC

Clients

ISDNanalogXDSL

LAN Firewall

Server

Internet

Emergency

National & Regional Health Networks

eHealth Uptake in EU

44

77 78

34

70 72

9

3746

5 7 12

0

20

40

60

80

100

1 2 3Source: Eurobarometer

2000 2001 2002

Doctors with internet connection

Online tine spent for educational purposes

Transfer of medical data

Telemedicine services

•• Despite the potential, the deployment of eHealth Despite the potential, the deployment of eHealth related technologies and services is relatively lowrelated technologies and services is relatively low

• eHealth less than 2% of healthcare expenditures in EU

• EU Health Telematics Industry POTENTIAL: 5% of Healthcare expenditures by 2010

europa.eu.int/comm/public_opinion/archives/special.htmeuropa.eu.int/comm/public_opinion/archives/special.htm

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PASTPAST 10 years (1991-2002)

FP2 FP3 FP4 FP5



and services

Budget

20M €Budget

100M €Budget

140M €Budget

200M €

Projects

30Projects

63Projects

158Projects

125Results

Feasibility Study

ResultsAIM

Community





Home-care systems

Personal Health Systems

NEXTNEXT 10 years (2003-2014)

eHealth COMMUNICATION

Coordination & Support to Regional -National Plans, International cooperation

eEurope 2005,

Ministerial eHealth Conferences

Technology assessment & transfer

Support to deployment

Communication: COM(2004) 356 final ‘e-Health – making healthcare better for European citizens: An

action plan for a European e-Health Area’

ee--Health action planHealth action plan: 3 areas of activities: 3 areas of activities••Addressing common challenges Addressing common challenges

••Pilot actions: accelerating beneficial implementationPilot actions: accelerating beneficial implementation

••Working together and monitoring practicesWorking together and monitoring practices

3 types of responsibilities: 3 types of responsibilities: ••Member States (MS) responsibility Member States (MS) responsibility

••European Commission (EC) ResponsibilityEuropean Commission (EC) Responsibility

••Shared between EC and MSShared between EC and MS

Many tools for action: Many tools for action: EC EC programmesprogrammes, EC promotion initiatives, , EC promotion initiatives, regional funds, MS funds, open method of coordinationregional funds, MS funds, open method of coordination

CALL 4 is open for submission of an Coordination Action that wiCALL 4 is open for submission of an Coordination Action that will ll assist Commission in following up the Action Plan of the eHealthassist Commission in following up the Action Plan of the eHealthCommunication COM (2004)356Communication COM (2004)356

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From R&D to deployment

Major categories of challenges

1.Organizational, cultural

2.National / regional strategy

3.Industrial issues

4.Legal issues, privacy -> security of data

5.Technology and standards

6.User acceptance

NEXTNEXT 10 years (2003-2014)PASTPAST 10 years (1991-2002)

FP2 FP3 FP4 FP5



and services

Budget

20M €Budget

100M €Budget

140M €Budget

200M €

Projects

30Projects

63Projects

158Projects

125Results

Feasibility Study

ResultsAIM

Community



@@



Home-care systems

Personal Health Systems Health Knowledge Infostructure & HealthGrid

Decision Support Systems

Biomedical Informatics – support to Molecular and genomics Medicine

Personal health systems (Wearable & Implantable) based on biosensors

www.cordis.lu/ist/directorate_c/ehealth/index.html

FP6 Research activities

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Wearable Health monitoring applications

•• fast access to vital data anywhere, anytimefast access to vital data anywhere, anytime

•• System for decision support and collaborationSystem for decision support and collaboration

•• Systems and infrastructures for health researchSystems and infrastructures for health research

•• Support to public health & managementSupport to public health & management

The Peres Centerfor Peace & Siemens

eHealth tools for Health ProfessionalseHealth tools for Health Professionals

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2.Bioinformatics/Genomics (BI)molecular and cell informatics

•Electronic Health Records•Decision Support Systems•Terminologies, ontologies•Telemedicine• Interoperability of systems

•Biosignal Analysis and Pattern Recognition•Neuro Algorithms•Neurocell Technology•Human Computer Interfaces•Machine Learning

•Structural Genomics•Functional Genomics•Proteomics•Biochip Technologies• Computational Biology

Medical Sciences

Behavioral SciencesSocial Sciences

Biological Sciences

Example: Advancing into the molecular causes of diseases: Genomic MedicineExample: Informatics in

support of the next generation of brain research: Molecular Neuroscience

Example: integration of genomic and neuroscience databases: Neurogenomics

DG INFSO.B.1/JCH/CVD/ 14.XII.2001/ “rings”v19/10/2001

1.Medical Informatics (MI)citizen, patient and population informatics

CB

D

3.Neuroinformatics (NI)cell to organ informatics

A

Biomedical Informatics:Knowledge Empowering Individual Health Care & Well-Being

•• Budget: 85MBudget: 85M€€

•• Focus 1: Focus 1: Ubiquitous Management of CitizenUbiquitous Management of Citizen’’s Health Statuss Health Status

• Submitted: 10 IPs, 2 NoEs, 24 STREPs, 3 SSA

• Accepted: 2 Ips, 2 STREPs

•• Focus 2: Focus 2: Decision Support Systems for Health ProfessionalsDecision Support Systems for Health Professionals

• Submitted: 33 Ips, 6 NoEs, 63 STREPs, 8 SSA, 4 CA

• Accepted: 3 IPs, 9 STREPs, 1 SSA

•• Focus 3: Focus 3: Biomedical InformaticsBiomedical Informatics

• Submitted: 2 IPs, 13 NoEs, 7 STREPs

• Accepted: 3 NoEs

FP 6 IST Call 1 Results in eHealth

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Call 4 - SO 2.4.11Integrated biomedical information for better Health

Objective: To support research and development of ICT based systems that process and integrateprocess and integrate all possible relevant biomedical information from different levels and from many biomedical information from different levels and from many different placesdifferent places with the purpose to improve

1. Health knowledge discovery and understanding2. Health status of an individual, i.e to improve disease prevention, diagnosis, treatment

Preallocated budget: 75 M€ (10% flexibility)Instruments: IPs: 55%; STREPs, SSAs and CAs: 45%Deadline: 22/3/2005

Background to call 4 – SO 2.4.11

Biomedical information is collected, stored and processed on / in

1)1) Different LevelsDifferent Levels – (molecule, cell, tissue, organ, person, population)

2)2) Different Context Different Context -- (care, research, education, policy/management)

3)3) Different RepresentationDifferent Representation – (format, structures, ontologies)

4)4) Many Many manymany different places different places - Medical info resources (health records, personal/wearable health systems, clinical research databases, drug/pharma databases, NLM, …)

- Public health info resources (epidemiological data and studies, national and WHO databases on diseases, …)

- Biomolecular Info resources (DNA & protein sequences, microrarraydata, protein interactions, human genome annotations ..)

- Environmental/Chemical/Biodiversity info resources

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Synthesis of all “Health Information levels”

Integrating biomedical data for better health

Bioinformatics

Medical Imaging

MedicalInformatics

Public HealthInformatics

Biomedical informatics

Background to call 4 – SO 2.4.11

Health statusHealth status of a person is determined by- endogenous determinants (genetic and acquired)- exogenous determinants (lifestyle, physical/social environment)

- health delivery system (quality and efficiency in prevention, early diagnosis, treatment, follow up, …)

Improving the health status for allImproving the health status for all requires

- better understanding of functions and roles of endogenous and exogenous determinants and to apply the new knowledge through

- better health delivery system – e.g. improvement in prevention, early diagnosis, disease management and support to personalisedhealthcare and support to lifestyle changes

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Objectives of Call 4 – SO 2.4.11

To support research and development of ICT based systems that process and integrateprocess and integrate all possible relevant biomedical biomedical information from different levels and from many different information from different levels and from many different placesplaces with the purpose to improve

1. Health knowledge discovery and understanding2. Health status of an individual, i.e to improve disease prevention, diagnosis, treatment

It is less about developing new technologies ( e.g. wearable monitoring systems) and more about optimal utilization of existing relevant information resources (data, signals, knowledge)

Scope of Call 4 – SO 2.4.11

Focus 1: Methods and systems for improved medical knowledge understanding through integration and processing of biomedical information

Examples:

- Methods and technologies to seamlessly link clinical and genetic information resources e.g. using grid technologies, resulting inintegrated biomedical information, e.g electronic health records including genetic information, and leading to measurable benefits in medical research or patient care

- Modelling, visualisation and simulation of patient specific data that integrate different levels of information e.g for new approaches to drug discoveries, simulation of functions of cells or organs

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Focus 2: Innovative systems and services for disease prevention,diagnosis and treatment based on integrated biomedical information.Examples: - Systems for disease prevention and chronic disease management by integrating data from personal monitoring systems, genetics and clinical information- Support to development of new “personalised” treatment and/or nutrition including new approaches to patient safety based on integrated biomedical information-Improvements to diagnostic methods by incorporating information from molecular level e.g. molecular imaging


ALL proposals must point or show: measurable benefits, respect legal & ethical guidelines

IPs: should address both focus 1 and 2 and should address the issue of integration and interoperability

STREP: should focus on development of innovative system or service with clearly specified problem and target group

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Calling for roadmaps (Specific Support Measures) that lead to • recommendations for an R&D actions on EU level • should also consider other aspects ( legal, industrial, financial)• should indicate beneficial intermediate milestones

i) Interoperability of eHealth systems – realistic approaches to this concept with clinical applicability. Special emphasis on semantic interoperability and the further R&D needed in the area of biomedical ontologies

ii) In silico model of human being (virtual or physiological human) from eCell to eOrgan. Should indicate possible realistic and exploitable milestones e.g. each 3-4 years.

iii) beneficial uptake of HealthGrid technologies and applications

Call 4 – SO 2.4.13Strengthening the Integration of the

ICT research effort in an enlargedEurope

•• Objectives:Objectives:

• Develop and validate innovative and efficient ICT-basedsystems and services in eHealth for the societal andeconomical development of the enlarged Europe

• With a view of strengthening the integration of the IST European Research Area

•• IntegrationIntegration::

• Level of collaboration between organisations

• Appropriate European dimension

•• Budget: 63 MBudget: 63 M€€

•• Instruments: Instruments: STREPsSTREPs

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Call 4 – SO 2.4.13

•• FocusFocus

• Advanced ICT-based eHealth systems and services:• Intelligent environment for health professionals

• Online health services for patients and citizens

• Integrated health information systems

• Exploiting advances in networking and mobile communications; ensuring interoperability with existingnetworks

• Building on best practices established throughout Europe

• Examples: Mobile applications for health monitoring, decision support for health professionals, home care monitoring and support to autonomy of patients

Conclusions

• 15 years of activities lead to many products and services that are currently being deployed. EC supports the beneficial deployment through an action plan

• New research activities have been launched in 6th FP on eHealth technologies and new interdisciplinary approaches for better understanding of disease and better support to health status of individuals

• CALL 4 is focusing on (vertical) INTEGRATION of biomedical information more than technological development

Documents

Call 4 eHealth activities until FP7 · monitoring systems) and more about optimal utilization of existing relevant information resources (data, signals, knowledge) Scope of Call 4