C e l l C y c l eC e l l C y c l e

Cell Size

Surface Area (length x width x 6)

Volume (length x width x height)

Ratio of Surface Area to Volume

Ratio of Surface Area to Volume in Cells

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Cell Cycle

The cell cycle represents recurring events that take place in the period of time from the beginning of one cell division to the beginning of the next. In addition to cell division, the cell cycle includes periods when the cell is growing and actively producing materials it needs for the next division.

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includes

is divided into is divided into

Cell Cycle

M phase (Mitosis)

Interphase

G1 phase S phase ProphaseG2 phase Metaphase TelophaseAnaphase

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M phase

G2 phase

S phase

G1 phase

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Centrioles

Chromatin

Interphase

Nuclear envelope

Cytokinesis

Nuclear envelope reforming

Telophase

Anaphase

Individual chromosomes

Metaphase

Centriole

Spindle

CentrioleChromosomes

(paired chromatids)

Prophase

Centromere

Spindle forming

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I n t e r p h a s eI n t e r p h a s e

n o r m a l c e l l a c t i v i t y

M i t o s i s

After D N A i s After D N A i s d u p l i c a t e d d u p l i c a t e d It is d i v i d e d It is d i v i d e d i n t o t w o i n t o t w o i d e n t i c a l i d e n t i c a l s e t s . s e t s .

After D N A i s After D N A i s d u p l i c a t e d d u p l i c a t e d It is d i v i d e d It is d i v i d e d i n t o t w o i n t o t w o i d e n t i c a l i d e n t i c a l s e t s . s e t s .

Centrioles

Chromatin

Interphase

Nuclear envelope

Cytokinesis

Nuclear envelope reforming

Telophase

Anaphase

Individual chromosomes

Metaphase

Centriole

Spindle

CentrioleChromosomes

(paired chromatids)

Prophase

Centromere

Spindle forming

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P r o p h a s eP r o p h a s e

c h r o m a t i n c o n d e n s e s i n to c h r o m o s o m e s

n u c l e a r m e m b r a n e d i s a p p e a r s

Centrioles

Chromatin

Interphase

Nuclear envelope

Cytokinesis

Nuclear envelope reforming

Telophase

Anaphase

Individual chromosomes

Metaphase

Centriole

Spindle

CentrioleChromosomes

(paired chromatids)

Prophase

Centromere

Spindle forming

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M e t a p h a s eM e t a p h a s e

c h r o m o s o m e s

l i n e u p a t t h e

c e l l e q u a t o r

Centrioles

Chromatin

Interphase

Nuclear envelope

Cytokinesis

Nuclear envelope reforming

Telophase

Anaphase

Individual chromosomes

Metaphase

Centriole

Spindle

CentrioleChromosomes

(paired chromatids)

Prophase

Centromere

Spindle forming

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A n a p h a s eA n a p h a s e

c h r o m o s o m e s m o v e t o

o p p o s i t e e n d s

o f t h e c e l l

Centrioles

Chromatin

Interphase

Nuclear envelope

Cytokinesis

Nuclear envelope reforming

Telophase

Anaphase

Individual chromosomes

Metaphase

Centriole

Spindle

CentrioleChromosomes

(paired chromatids)

Prophase

Centromere

Spindle forming

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T e l o p h a s eT e l o p h a s e

c h r o m o s o m e s d i s a p p e a r

n u c l e a r m e m b r a n e r e f o r m s c e l l b e g i n s t o d i v i d e

Centrioles

Chromatin

Interphase

Nuclear envelope

Cytokinesis

Nuclear envelope reforming

Telophase

Anaphase

Individual chromosomes

Metaphase

Centriole

Spindle

CentrioleChromosomes

(paired chromatids)

Prophase

Centromere

Spindle forming

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Contact Inhibition

A sample of cytoplasm is removed from a cell in mitosis.

A sample is injected into a second cell in G2 of interphase.

As a result, the second cell enters mitosis.

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C a n c e r

U n c o n t r o l l e d U n c o n t r o l l e d C e l l D i v i s i o n C e l l D i v i s i o n

U n c o n t r o l l e d U n c o n t r o l l e d C e l l D i v i s i o n C e l l D i v i s i o n

S p r e a d o f C a n c e rS p r e a d o f C a n c e r

C e l l C y c l eC e l l C y c l e

E n dE n d