Brief Intervention for Substance Abuse after TBI John D. Corrigan, PhD Ohio Valley Center for Brain Injury Prevention and Rehabilitation Ohio State University

Brief Intervention for Substance Abuse after TBI

John D. Corrigan, PhD

Ohio Valley Center for

Brain Injury Prevention

and Rehabilitation

Ohio State University

Mitchell Rosenthal, PhD

1949-2007

% Rehabilitation Patients with Prior Histories of Abuse

43%

54%58%

29%34%

39%

48%

58%61%

0%

10%

20%

30%

40%

50%

60%

70%

Alcohol OtherDrugs

Either

TBI ModelSystems

Ohio StateUniversity

University ofWashington

Problem Substance Use Before and After Moderate and Severe TBI

29%28% 27%

14%15%

20%

4% 5%7%

0%

5%

10%

15%

20%

25%

30%

35%

Pre not post Pre and post Post not pre

1 yr post (N=3635)

2 yrs post (N=2656)

5 yrs post (N=972)

Pre-injury Substance Abuse in Those Lost to Follow-up 1 year Post-injury

(Corrigan et al., 1997)

0%

20%

40%

60%

80%

100%

Lost @ 1 Year Found @ 1 Year

Prior Substance Abuse

No Prior Abuse

Binge Drinking 1 Yearafter Hospitalization for TBI

[Horner, et al, 2005 (South Carolina Follow-up Study)]

52%

70%

22%

14%

26%

16%

0%

20%

40%

60%

none 1 or 2 3 or more

# binging occasions last 30 days

TBI (SCTBIFR)

Gen'l Pop (BRFSS)

Percentage With Needs Unmet at 1 Year

12.7%

19.6%

26.9%

29.5%

33.1%

44.2%

55.6%

68.0%

71.0%

73.6%

83.6%

95.9%

78.3%

Personal assistance

Self-care

Traveling in the community

Home making

Coordinating services

Managing money

Managing stress

Participating in recreation

Improving cognition

Controlling temper

Controlling substance use

Improving job skills

Finding work

Corrigan, Whiteneck & Mellick (2004)

Percentage with Unmet Needs at 1 Year

41.2%

49.7%

53.9%

57.8%

61.2%

66.5%

72.0%

89.7%

78.0%

Opportunities to socialize

Personal assistance

Home making

Improving job skills

Information about services

Managing stress

Coordinating services

Controlling substance use

Finding work

Pickelsimer et al. (2007)

Traumatic Brain Injury

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High Severity

High Severity

Quadrant I Quadrant II

Quadrant III Quadrant IV

4 Quadrant Model of Services


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High Severity

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Quadrant I

Acute Medical Settings and Primary Care

Quadrant II

Rehabilitation Programs & Services

Quadrant III

Substance Abuse System

Quadrant IV

Specialized TBI & Substance Abuse

Services

4 Quadrant Model: Place of Service Provision


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Screening & Brief Interventions

Quadrant II


Education, Screening, Brief Interventions &

Linkage

Quadrant III


Screening, Accommodation

& Linkage

Quadrant IV


Services

Integrated Programming

4 Quadrant Model: Types of Services


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Linkage

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Quadrant II


Education, Screening Brief Interventions &

Linkage

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& Linkage

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Services




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Quadrant II



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Screening, Accommodation &

Linkage

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High Severity

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Quadrant II



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& Linkage

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Specialized TBI & Substance Abuse Services




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High Severity

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Screening & Brief Interventions (SBI)

• Brief, opportunistic, counseling and referral conducted in a medical context (e.g., physician’s office, Emergency Department, Trauma Program)

• Clinical trials support both efficacy and cost-effectiveness for less severe alcohol problems

• Most studied are the WHO model for primary care (currently promoted by CDC and NIAAA) and “FRAMES” developed by Gentilello and colleagues at University of Washington for use in Emergency Departments & Trauma Centers.

1644

465

198247

482

808

155 16389 133

0

200

400

600

800

1000

1200

1400

1600

1800

Total Psych GI Injury ARDs

Control

Intervention

• GGT decreased in both groups

• Fewer sick days in intervention group

• 10 control, 5 inter-vention deaths

Efficacy of Screening & Brief Intervention

Kristenson H, et al. Alcohol Clin Exp Res 1983;7:203 Hospital Days 5 years post-intervention

• RCT, 17 practices, 64 physicians• N=774

– Men >14 drinks/wk– Women >11 drinks/wk

• 93% 12 month follow-up• Control: health booklet• Intervention: health booklet + 2 10-15”

physician discussions and a follow-up nurse phone call

In Primary Care: Project TrEATFleming MF, Lawton Barry K, et al. JAMA 1997;277:1039

Control before/after

Intervention before/after

Drinks/7d* 19/16 (-18%) 19/12 (-40%)

Binges/30d* 5/4 (-21%) 6/3 (-46%)

Hosp days* 42/146 (+248%) 93/91 (-1%)

Project TrEAT Results

*p<0.001

FRAMES StudyGentilello, Rivara, Donovan, Jurkovich, et al. (1999)

• 762 Level 1 trauma patients who screened positive for problem alcohol use

• Randomly assigned to Screening & Brief Intervention (SBI) or standard care

• 12 months later those receiving SBI :– Reduced alcohol consumption by 21.8 drinks/wk. (vs. 6.7

for the control group)– Reduction most apparent in patients with mild to moderate

alcohol use problems– SBI group had 47% reduction in ER or trauma admissions

• 3 years later, SBI group had 48% reduction in injuries requiring hospitalization

WHO Model of SBI

Screening

• Distinguish among abstainers, low-risk use, at-risk use and substance use disorder

Intervention

• If low risk, advise not to increase

• If at-risk, advise and assist depending on readiness to change

• If substance use disorder, advise, refer and/or treat

FRAMES Components

Feedback: respectfully give specific information that concerns the patient

Responsibility: stress that the patient is responsible for any change

Advice: respectfully give advice to the patient

Menu: offer the patient choices

Empathy: listen and reflect

Self-efficacy: reinforce that change is possible and will be beneficial

FRAMES Process• Make introduction and attend to patient’s

agenda• Introduce substance use agenda• Assess readiness to change:

– If precontemplative, goal is to raise doubt– If contemplative, goal is to increase

ambivalence– If ready to take action, goal is to elicit a

commitment• Utilize FRAMES components• Close on good terms

SBI Summary

• Screening and Brief Intervention (SBI) has become the standard of care

• Takes advantage of the opportunity created by recently experienced consequences

• SBI appears effective for reducing use among heavy users and abusers, less so those with dependence

• Reduced use reduces subsequent injuries• Patients with moderate and severe TBI often excluded from research and clinical protocols

• Need to develop SBI protocols specifically for persons with TBI

SBI for TBI

• If used acutely, how to address confusion and/or diminished cognitive functioning?

• How can an interdisciplinary team optimize the impact of SBI?

• Are there opportunities to use SBI later post-injury:

–Case managers?

–Vocational rehabilitation counselors?

• Who should the target audience be?

Substance Use Disorders and Problem Substance Use

• Substance Dependence (DSM-IV)

• Substance Abuse (DSM-IV) or High Risk Use (ICD-9 CM)

• Unhealthy Use (Dietary Guidelines for Americans)

Unhealthy Alcohol Use(Dietary Guidelines for Americans)

•Any use of illicit drugs, including alcohol by children.•Alcohol use for adults

–Men ≤ 65 years old--no more than 2 drinks per day

>65 years old--no more than 1 drink per day–Women --no more than 1 drink per day

•Abstain from alcohol when pregnant or considering pregnancy, when taking a medication that interacts with alcohol; if a contraindicated medical condition is present (e.g., ulcer, liver disease), or if alcohol dependent.

– If at risk for heart disease, consider potential benefits and risks of alcohol use: light to moderate drinking is associated with lower rates of coronary heart disease in certain populations (e.g., men over 45, postmenopausal women).

– Infrequent or nondrinkers are not advised to begin drinking to reduce the risk of coronary heart disease because vulnerability to alcohol-related problems cannot always be predicted.

– Similar protective effects can likely be achieved through proper diet and exercise.

Unhealthy Use (Dietary Guidelines for Americans)


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A User’s Manual

Eight Educational Messages

1. People who use alcohol or other drugs after they have a brain injury don’t recover as much.

2. Brain injuries cause problems in balance, walking or talking that get worse when a person uses alcohol or other drugs.

3. People who have had a brain injury often say or do things without thinking first, a problem that is made worse by using alcohol and other drugs.

4. Brain injuries cause problems with thinking, like concentration or memory, and using alcohol or other drugs makes these problems worse.

Eight Educational Messages

5. After brain injury, alcohol and other drugs have a more powerful effect.

6. People who have had a brain injury are more likely to have times that they feel low or depressed and drinking alcohol and getting high on other drugs makes this worse.

7. After a brain injury, drinking alcohol or using other drugs can cause a seizure.

8. People who drink alcohol or use other drugs after a brain injury are more likely to have another brain injury.

Screening and Brief Intervention in Acute Rehabilitation

• 60 Ss with TBI receiving acute rehab

• 3 conditions (interventions randomized): – baseline/standard of care– booklet only intervention– booklet + video intervention

• Information retained, attitudes, and use measured 30 days following discharge

Abstaining 30 days post-discharge

83%88%

78%83%

0%

20%

40%

60%

80%

100%

Baseline Booklet only Booklet + video All Subjects

Abstaining 30 days post-discharge

83%88%

78%83%

0%

20%

40%

60%

80%

100%


Abstaining and Facts Recalled

85% 83%

64%

78%80%

100% 100%94%

0%

20%

40%

60%

80%

100%

Baseline Booklet only Booklet +video

All Subjects

<3 recalled3 recalled

Abstaining and Facts Recalled

85% 83%

64%

78%80%

100% 100%94%

0%

20%

40%

60%

80%

100%

Baseline Booklet only Booklet +video

All Subjects

<3 recalled3 recalled

Length of PTA and Facts Recalled

19.821.3 20.8 20.6

6.8 6.8

19.5

12.0

0

5

10

15

20

25

30


<3 recalled

3 recalled

Length of PTA and Facts Recalled

19.821.3 20.8 20.6

6.8 6.8

19.5

12.0

0

5

10

15

20

25

30


<3 recalled

3 recalled

Screening and Brief Intervention (SBI) for More Serious TBI

1. Give booklet and introduce videotape

2. Play the videotape

3. Ask: “Do you have any questions?”

4. Say: “We hope it is clear…we recommend no drinking alcohol or use of illicit drugs.”

5. Ask: “On a scale of 1 to 10…how important is it that you not use alcohol or illicit drugs?”

SBI for More Serious TBI (cont’d)

If low importance (1-3) ask: “Which of the reasons for not using made the most sense to you?”

Use open-ended questions and reflective listening to explore patient’s views on negative effects of substance use on recovery from TBI.


If moderate importance (4-6) ask: “It sounds like you’re not sure about your use. What do you think would be some good reasons for not using?”

After reflective listening, summarize and ask “What are some things that would make it hard not to use?” Again, listen and summarize.


If high importance (7-10) ask: “It sounds important to you not to use. What do you think would help you accomplish that?”

During reflective listening reinforce self-motivational statements and support self-efficacy.


For all patients, conclude interview by:

Eliciting up to 3 reasons why it would be a good idea not to use substances

Re-capping the key, positive motivational issues.

Conclusions•SBI may be an important tool for addressing substance use among persons with TBI.

•Need to determine if and how SBI needs to be adapted for persons with more serious TBI.

•The field needs consensus about the level of use we should target and the behavior we will recommend.

•We need to consider both acute and chronic opportunities to use SBI.

•We need a lot more research.

Documents

Brief Intervention for Substance Abuse after TBI John D. Corrigan, PhD Ohio Valley Center for Brain Injury Prevention and Rehabilitation Ohio State University