Breast Cancer and Complications for One Patient

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    Running head: BREAST CANCER 1

    A Patient with Breast Cancer:

    Complications and Co-morbidities

    Sarah Firmin

    University of North Florida

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    BREAST CANCER 2

    A Patient with Breast Cancer: Complications and Co-morbidities

    F.T. is a 73 year- old African American female who has been in the hospital for 18 days

    following a double mastectomy on August 10, 2012. After her surgery she experienced

    complications including severe sepsis secondary to a urinary tract infection, anemia, gastritis,

    formation of a pressure ulcer on her buttock, and generalized weakness. She is obese. Being

    obese affects her recovery in many ways; she becomes short of breath upon minimal exertion,

    has generalized joint pain, and has reported feeling tired on a consistent basis. Being obese also

    increased her likelihood for the initial development of breast cancer (LeMone, Burke, &

    Bauldoff, 2011).

    She has a prior diagnosis of type two diabetes mellitus (DM) and has had periods in the

    hospital when her glucose level has been over 200mg/dl. Surgical patients with blood glucose

    levels over 200mg/dl have higher rates of infection (LeMone, Burke, & Bauldoff, 2011).

    Controlling her glucose level has been difficult because F.T. has refused to eat at times, she is

    inactive, and she has expressed feelings of emotional stress. As a result of type 2 DM, she has

    i h l th Thi h i t d h F T h t h f t f

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    BREAST CANCER 3

    Breast Cancer

    Heredity is a non-modifiable risk factor which causes breast cancer. Two genes, BRCA1

    and BRCA2, are cancer susceptibility genes. A woman has an 80% chance of developing breast

    cancer if one of these genes is inherited (Crowley, 2012). Family history has been identified as

    the leading indicator for the risk of breast cancer; however, breast cancer can also be caused by

    environmental, hormonal, and reproductive factors (LeMone, Burke, & Bauldoff, 2011).

    Breast cancer begins as one cell mutates from being a regular cell to a cell that grows and

    multiplies too rapidly and forms a tumor. The proliferation of cancerous cells is dependent upon

    hormones (LeMone, Burke, & Bauldoff, 2011); estrogen, progesterone, growth hormone,

    prolactin, and adrenal corticosteroids influence the action of the cells (Crowley, 2012). An

    alteration in these hormone levels may slow the rate of cell multiplication. Estrogen and

    progesterone initiate activity in nearly 60% of cancerous cells; the cells that respond to these

    hormones have specific protein receptors and without the hormones the cells exhibit regression

    (Crowley, 2012).

    The HER-2 gene causes the proliferation of approximately 25% of tumor cells (Crowley,

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    BREAST CANCER 4

    cells is an area of necrosis. Calcium salts exit the bloodstream and enter the necrotic tissue, and

    the calcium may be felt while performing a self-breast exam.

    The cancer is noninvasive if there is no infiltration to the surrounding tissue. If the tumor

    breaks through the ducts or lobules into the surrounding breast tissue, the tumor is invasive

    (LeMone, Burke, & Bauldoff, 2011). Metastasis occurs when a tumor secondary to an original

    tumor forms; the cancer spreads to an organ or a part of the body that was not associated with the

    original tumor (LeMone, Burke, & Bauldoff, 2011). Breast cancer will often first metastasize to

    the regional lymph nodes which are located above the breast towards the underarm before

    metastasizing in more distant sites (Crowley, 2012). In addition to the lymph nodes, metastasis

    commonly occurs in the bones, brain, lungs, liver, and skin (LeMone, Burke, & Bauldoff, 2011).

    The proliferation of cell division will often trigger a response which initiates the

    formation of excess fibrous tissue around the tumor. The fibrosis may be a protective attempt by

    the body to contain the cancer from spreading (Crowley, 2012). This may make the cancer feel

    hard; it may make the skin appear dimpled, and may have uneven borders that merge into the

    bordering breast tissue. The cancerous lump in the breast may be nontender. The nipple may

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    BREAST CANCER 5

    in the liver release insulin into the blood stream which triggers skeletal muscles and fat to

    increase the absorption of glucose, lowering the blood glucose level. Insulin resistance occurs

    when skeletal muscle and fat tissue do not respond to insulin. When the body is in a of state

    insulin resistance, glucose levels build up in the blood stream instead of going into the cells of

    skeletal muscle and fat, creating a state of hyperglycemia (LeMone, Burke, & Bauldoff, 2011).

    The liver also becomes resistant to insulin in type 2 DM (Mahler, & Adler, 1999).

    Insulin is released from beta cells in the pancreas. In a healthy individual, insulin signals the

    liver is to withhold excretion of glucose. Insulin resistance from the liver creates an environment

    where glucose is excreted regardless of circulating insulin levels. Over time, the glucose

    production is continually increased and is excreted after fasting and postprandial (Mahler, &

    Adler, 1999). The liver begins to use glucose less as glucokinase activity decreases, and yet the

    liver continues to overproduce glucose (Mahler, & Adler, 1999). In the pancreas, beta cell

    function begins to decline before eventually ceasing action (Mahler, & Adler, 1999).

    F.T. is obese and physically inactive, which are risk factors for type 2 DM. These are

    also risk factors for her chief complaint of breast cancer. An additional risk factor for type 2 DM

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    BREAST CANCER 6

    pressure of 120-139 mm Hg over a diastolic pressure of 80-89 mm Hg, while hypertension is the

    systolic pressure equal to or greater than 140 mm Hg over the diastolic pressure equal to or

    greater than 90 mm Hg (Brashers, 2008). In order to diagnose a patient as hypertensive, the

    diagnostic blood pressure measurement must be an average of the pressures taken on three

    different instances (LeMone, Burke, & Bauldoff, 2011).

    Blood pressure is affected by an elevated vascular volume, which may occur due to a

    decrease in the excretion of salt. Persons with hypertension generally expel a lower amount of

    salt in the urine than persons without hypertension (Brashers, 2008). The renin-angiotensin-

    aldosterone system (RAAS) is responsible for controlling vascular tone and signaling the kidneys

    to release or retain water and salt. An impaired RAAS system will result in an increase of

    sodium and fluid, which increases the pressure on the vessel walls due to the heightened blood

    volume (Brashers, 2008). Specifically, angiotensin II stimulates vasoconstriction, and the

    sympathetic nervous system, and prompts aldosterone to manipulate the retention of sodium and

    fluids by the kidney (Brashers, 2008).

    Persistently high angiotensin II levels also contribute to ventricular remodeling. This

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    BREAST CANCER 7

    (Brashers, 2008). A goal of this action is to increase the contraction strength of the heart, which

    increases the cardiac output and provides the muscles with more blood. Concurrently, the

    adrenal medulla gland releases catecholamines which cause vasoconstriction (Brashers, 2008).

    Continual excitation of the neuroreceptors leads to continual constriction of the vascular

    system and a raised heart rate. Vascular remodeling occurs in this process, and procoagulant

    effects can be seen (Brashers, 2008). The continual elevation of the SNS causes blood pressure

    to become elevated.

    Released from heart cells, atrial natriuretic peptide (ANP) also affects vasomotor tone

    and blood volume (LeMone, Burke, & Bauldoff, 2011). This natriuretic hormone inhibits both

    aldosterone secretions from the adrenal gland and anti-diuretic hormone from the pituitary gland.

    This process allows for more water to be excreted in the urine (LeMone, Burke, & Bauldoff,

    2011). Other natriuretic hormones such as brain natriuretic peptide and C-type natriuretic

    peptide work to maintain a balanced relationship between salt and water in the body (Brashers,

    2008). If a deficient intake level of potassium, magnesium, and calcium occurs, or if an excess

    of sodium intake occurs, the balance is offset and too much sodium can be retained in the body

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    BREAST CANCER 8

    Contributing factors to hypertension also include resistance to insulin, hyperinsulinemia

    and the functioning ability of endothelial cells (Brashers, 2008). Superfluous insulin contributes

    to the retention of sodium by the kidneys and an increase in SAS action. In addition, vascular

    smooth muscles become hypertrophic in the presence of excess insulin, and the ability to

    transport ions across the cell membrane is impaired (LeMone, Burke, & Bauldoff, 2011).

    Hypertension is the most common comorbidity in cancer patients (Mouhayar, &

    Salahudeen, 2011). While the rate of hypertension is the same for persons that do not cancer and

    those with cancer before chemotherapy, after chemotherapy the rate of hypertension rises

    dramatically (Mouhayar, & Salahudeen, 2011). If hypertension cannot be controlled, the patient

    may not be eligible for certain treatments. Blood pressure monitoring is critical throughout the

    cancer treatment process in order to prevent end-organ damage (Mouhayar, & Salahudeen,

    2011).

    Physical Assessment

    F.T. was sitting in the bed with the head of the bed at an 80 degree angle. Her weight is

    196lbs. Her vital signs were taken at 0900. Her respiratory rate was 20 inhalations per minute,

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    BREAST CANCER 9

    nose was without drainage. The tongue was midline; the mucus membranes appeared dry and

    light pink, and her dental hygiene was poor. Her pupils were equal, round, and reactive to light

    and accommodation. The patient appeared to have been barrel chested. Her respiratory rate was

    regular and unlabored. The lungs were clear to auscultation; diminished breath sounds were

    noted bilaterally in the lower lobes. There was no cough or mucous discharge. Her heart rate of

    98 beats per minute was regular and free of murmurs. S1 and S2 were auscultated. The carotid,

    radial, and pedal pulses were regular however the radial and pedal pulses were weak (graded as a

    +1). She had pitting +3 edema in her lower extremities. The skin under her fingernails and

    toenails was tinged brown due to chemotherapy treatments; the capillary refill time was therefore

    unable to be measured.

    F.Ts abdomen was soft, obese, without visible peristalsis, and non-tender. Tympany

    was heard upon percussion, and normal bowel sounds were present in all four quadrants. She

    self-reported her last bowel movement as occurring on August 28, 2012; when possible she

    ambulated to the bedside commode for bowel movements. A Foley catheter was removed on

    August 26, 2012, and an adult brief was worn for urination. The patient was able to lift her arms

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    BREAST CANCER 10

    a score of 15 on the Glasgow Coma Scale. Her mood was congruent and appropriate. She stated

    that she was depressed, tired, and sad. She also noted that she wanted to leave the hospital.

    Diagnostic Testing and Laboratory Results

    F.T. had a bilateral mastectomy on August 10, 2012. On August 8, 2012, after the patient

    reported difficulty breathing, she had x-rays of the chest which showed mild cardiomegaly,

    infiltrate in the right upper lung lobe, and shallow lung volume. A sonogram of the chest and

    mediastinum was taken on August 16, 2012 which showed a mass in the region of the right

    breast with heterogeneous echogenicity which measured 16cm by 7cm. She had a second mass

    in the same area which measured 9.4cm by 3.7cm. These masses were found to most likely be

    representative of hematomas. A chest x-ray was taken again on August 17, 2012; the lungs had

    developed bibasilar atelectasis versus the prior infiltrate, and the cardiac silhouette was enlarged.

    After complaints of severe abdominal pain, her stomach was biopsied on August 21,

    2012 and there was no evidence of intestinal metaplasia or dysplasia. She was found negative

    for helicobacter organisms; an x-ray was taken to examine the abdomen and found no free

    intraperitoneal air. On August 22, 2012 she underwent a Computed Tomography (CT) scan

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    BREAST CANCER 11

    liver function tests

    Na 146 (H)

    K 4.1

    Cl 112 (H)

    CO2 29

    Anion Gap 5

    Glucose 123 (H)

    BUN 9

    Creatine 0.97

    GFR

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    BREAST CANCER 12

    WBC 7.7

    RBC 3.09 (L)

    HGB 7.9 (L)

    HCT 25.6 (L)

    MCV 82.8

    MCH 25.6 (L)

    MCHC 30.9 (L)

    RDW 18.4 (H)

    PLT 316

    NEUT % 69.4

    LYMPH % 18.4

    MONO % 9.5

    EOS % 2.6

    BASO % 0.1

    NEUT # 4.9

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    BREAST CANCER 13

    August 27, 2012 at 0348 102

    August 27, 2012 at 0702 107

    August 27, 2012 at 1126 176 (H)

    August 27, 2012 at 1639 122 (H)

    August 27, 2012 at 2024 234 (H)

    August 28, 2012 at 0038 162 (H)

    August 28, 2012 at 0247 134 (H)

    Medications

    F.T. is taking Heparin Sodium, Hydralazine HCL, Insulin Detemir, Insulin lispro,

    Morphine, Gabapentin, Oxybutynin Chloride, Percocet, Pantoprazole, Rosuvastatin Calcium.

    Medication purpose, mechanism of action, class of drug, potential side effects, and the

    evaluation of each medication is in Appendix A.

    Summary of Treatment and Plans for Discharge

    F.T. has a strong desire to leave the hospital. Having motivation is important because she

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    BREAST CANCER 14

    References

    Ackley, B.J., & Ladwig, G.B. (2011).Nursing diagnosis handbook: A guide for planning care.

    (9th

    ed.). St. Louis, MO: Mosby.

    Brashers, V. (2008). Alterations in cardiovascular function. In S. Huether, K. McCance, V.

    Brashers, & N. Rote (Eds.), Understanding pathophysiology (pp. 607-676). St. Louis,

    MO: Mosby.

    Cowley, L. (2010).An introduction to human disease. (8th

    ed.).Sudbury, MA: Jones & Bartlett

    Deglin, J. H., & Vallerand, A. H. (2009).Daviss drug guide for nurses (11th

    ed.). Philadelphia,

    PA: F.A. Davis

    LeMone, P., Burke, K., & Bauldoff, G. (2011).Medical-surgical nursing: Critical thinking in

    patient care (5th

    ed.). Boston, MA: Pearson.

    Mahler, R., & Adler, M. (2011). Type 2 diabetes mellitus: Update on diagnosis,

    pathophysiology, and treatment. The Journal of Clinical Endocrinology &

    Metabolism, 84(4), 1165-1171. doi: 10.1210/jc.84.4.1165

    Mouhayar, E., & Salahudeen, A. (2011). Hypertension in cancer patients. Texas Heart Institute

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    Running head: BREAST CANCER 15

    Appendix A

    MEDICATION

    NAME &

    CLASSIFICATION

    DOSE, TIME,

    FREQUENCY &

    ROUTE

    MECHANISM OF

    ACTION

    MAJOR & COMMON

    SIDE EFFECTS

    RATIONALE FOR

    THIS CLIENT

    NURSING

    CONSIDERATIONSEvaluation of

    MedicationEffects

    Heparin Sodium

    Anticoagulant

    5000U

    Every 12 hours

    0900, 2100Subcutaneous

    Potentiates

    inhibitory

    effect ofantithrombin

    on factor Xaand thrombin.Prevents the

    conversion of

    prothrombinto thrombin

    by its effectson factor Xa.

    Anemia,

    thrombocytopenia,

    bleeding.

    Patient is

    spending the

    majority of herdays and nights

    in bed. Thismedication willhelp to prevent

    blood clots

    from forming.

    Consistently

    assess for signs

    of bleeding andhemorrhage

    (bleeding gums,nose bleeds,black tarry

    stools, a fall in

    hematocrit orblood pressure).

    Medication is

    having desired

    effect. Patientptt is 2. Patient

    does not showsigns ofcomplications.

    Hydralazine

    HCL

    (Apresoline)

    Anti-hypertensive

    Vasodilator

    25mg

    Every 8 hours

    0600, 1400,2200

    Oral

    Direct- acting

    peripheral

    arteriolarvasodilator

    which lowersblood

    pressure in

    hypertensivepatients.

    Tachycardia,

    sodium retention,

    drug inducedlupus syndrome.

    Patient has

    hypertension.

    Thismedication aids

    in controllingsymptoms.

    Monitor blood

    pressure and

    pulse frequentlyduring therapy;

    note anychanges.

    Monitor

    electrolytes

    Blood pressure

    at 0735 was

    197/77. 0900blood pressure

    190/74. 0600medication was

    not given until

    0900 due tonurse error.

    Blood pressureat 1000 was

    Medication Worksheet

    Patient Initials F.T. Date Seen August 27, 2012

    https://www.google.com/url?url=http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000626/&rct=j&sa=X&ei=DoZKUMvnFsPI2gWyyICICg&ved=0CB8Q8Q4wAA&q=Hydralazine&usg=AFQjCNE1uHUi0Oc-ycb5QLrpDNmRrS04aQhttps://www.google.com/url?url=http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000626/&rct=j&sa=X&ei=DoZKUMvnFsPI2gWyyICICg&ved=0CB8Q8Q4wAA&q=Hydralazine&usg=AFQjCNE1uHUi0Oc-ycb5QLrpDNmRrS04aQhttps://www.google.com/url?url=http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000626/&rct=j&sa=X&ei=DoZKUMvnFsPI2gWyyICICg&ved=0CB8Q8Q4wAA&q=Hydralazine&usg=AFQjCNE1uHUi0Oc-ycb5QLrpDNmRrS04aQ
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    BREAST CANCER 16

    166/84.

    Medication

    administrationhad positive

    effect, howeverpatient

    remainedhypertensive.

    Patient lab

    value ofsodium high

    (146). This is

    a possible sideeffect of the

    medication.Patient plan is

    to increasefluids to lower

    the value. No

    other sideeffects.

    Insulin Detemir(Levemir)

    Antidiabetics

    Hormones

    Pancreatics

    4units1x daily

    BedtimeSubcutaneous

    Lowerglucose by

    stimulatingglucose

    uptake in

    skeletalmuscle and

    fat, inhibitinghepatic

    glucose

    production.Onset: 3-4

    Hypoglycemia,anaphylaxis

    Thismedication is

    indicated forpatients who

    have type 2

    DM, which thispatient has.

    Assessment ofsymptoms for

    hypoglycemia,and

    hyperglycemia.

    Monitor weightperiodically.

    May causedecrease in

    phosphate,

    magnesium,and potassium

    Drugadministration

    has desiredeffect,

    although blood

    glucose levelremains high.

    On August 27,2012 at 2024,

    the level was

    234.Medication

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    BREAST CANCER 17

    hours.

    Peak: 3-14

    hours.Duration: 24

    hours.

    levels. Monitor

    glucose four

    times daily, andmore

    commonlyduring stress.

    was

    administered,

    and the levelwas checked

    again onAugust 28,

    2012 at 0038.The level had

    fallen to 162.

    By 0237, thelevel had

    dropped further

    to 154. Patientdoes not

    experiencenegative side

    effect frommedication.

    Insulin lispro(Humalog)

    Antidiabetic

    Hormones

    Pancreatics

    Sliding Scale:Blood sugar

    350: callendocrinologist

    After meals and1600

    Subcutaneous

    Lowerglucose by

    stimulating

    glucoseuptake in

    skeletalmuscle and

    fat, inhibiting

    hepaticglucose

    production.Onset: 15-30

    minutes.

    Peak: 2-8hours.

    Hypoglycemia,anaphylaxis

    Controlsinsulin in

    patients with

    type onediabetes or type

    2 DM. Patienthas type 2 DM.

    Assessment ofsymptoms for

    hypoglycemia,

    andhyperglycemia.

    Monitor weightperiodically.

    May cause

    decrease inphosphate,

    magnesium,and potassium

    levels. Monitor

    glucose fourtimes daily, and

    Patient needed4u before

    breakfast on

    August 27,2012 when

    blood glucosewas 177.

    Patient does

    not have anyadverse side

    effects, and themedication has

    a positive

    effect onoverall health.

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    BREAST CANCER 18

    Duration: 24

    hours.

    more

    commonly

    during stress.

    Morphine

    Opioid

    analgesics

    Opioid agonist

    2mgEvery 4 hours

    as needed

    IV

    Binds toopiate

    receptors in

    the CNS.Alters the

    perception of

    and responseto pain.

    Producesgeneralized

    CNSdepression.

    Confusion,sedation,

    hypotension,

    constipation,respiratory

    depression.

    Patient hassevere pain

    associated with

    her doublemastectomy

    and infection.

    Use a pain scalebefore and after

    administration

    to quantifypatient pain.

    Assess: level of

    consciousness,blood pressure,

    pulse, andrespirations

    before, during,and after

    administration.

    Assess geriatricpatient more

    frequently; thisgroup is more

    susceptible to

    effects ofopioids.

    Medication hasdesired effect

    of lowering

    pain. Pre-administration

    of medication,

    patient self-reported pain

    as a level 8 ona scale from 1

    to 10. After anhour, the pain

    was reassessed

    and the painlevel had

    dropped to a 5.The patient has

    constipation

    which is anadverse side

    effect ofmorphine; no

    other adverse

    side effects.

    Gabapentin

    (Neurontin)

    Analgesicadjunct

    100mg

    1x daily0900

    Oral

    Mechanism

    of action notknown. May

    affect thetransport of

    amino acids

    Confusion,

    depression,drowsiness, ataxia,

    paresthesia, facialedema.

    An unlabeled

    use of thismedication is

    for the relief ofchronic pain.

    Patient has

    Assess location,

    duration, andintensity of

    pain.

    The patient has

    diabetes, anddue to the

    diabetes shehas peripheral

    neuropathy.

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    BREAST CANCER 19

    Mood stabilizer across and

    stabilize the

    neuronalmembranes.

    chronic pain

    resulting from

    peripheralneuropathy.

    This

    medication is

    primarily forthe pain

    associated withthat condition.

    Medicationalone does not

    resolve all of

    the issuesclient has in

    relation to

    pain, however,when used in

    conjunctionwith other pain

    relief, thepatient

    experiences

    less pain.Patient needs

    ongoingmonitoring of

    pain.

    Oxybutynin

    Chloride

    (Ditropan)

    Urinary tractantispasmodic

    Anticholergenic

    5mg

    1x daily

    0900Oral

    Inhibits the

    action of

    acetylcholineat prostgan-

    glionicreceptors.

    Has direct

    spasmolyticaction on

    Dizziness,

    drowsiness,

    constipation, drymouth, nausea,

    urinary retention.

    Patient has

    stress urinary

    incontinence.

    Monitor

    voiding pattern

    and intake andoutput ratios,

    and assessabdomen for

    distention. In

    geriatricpatients, assess

    Medication is

    having desired

    effect andpatient is not

    voiding due tostress

    incontinence.

    The patient isnot taking in

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    BREAST CANCER 20

    smooth

    muscle lining

    the GU tract,without

    affectingvascular

    smoothmuscle.

    for sedation and

    weakness.

    fluids, creating

    a low urine

    output. Thepatient is

    experiencingconstipation.

    Patient istaking Colace

    100mg daily at

    bed tocounteract this

    effect. She has

    not complainedof the other

    adverse effects.

    Oxycodone/

    Acetaminophen(Percocet)

    Opioid

    Analgesic

    5mg

    Every 4 hoursas needed

    Oral

    Binds to

    opiatereceptors in

    the CNS.Alters

    response to

    andperception of

    painfulstimuli, while

    producing

    generalizedCNS

    depression.

    Confusion,

    sedation,respiratory

    depression,constipation,

    orthostatic

    hypotension,urinary retention.

    This

    medication isindicated for

    moderate tosevere pain.

    Patient has pain

    due to recentdouble

    mastectomy.

    Assess type,

    location, andintensity of pain

    prior to and 1hour after

    administration.

    Assess bloodpressure, pulse,

    and respirationsbefore and

    periodically

    duringadministration.

    If respirations

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    BREAST CANCER 21

    function

    regularly.

    Preventconstipation

    with increasedfluids, fiber,

    and laxatives.

    along with

    Hydralazine

    HCL, maycause urinary

    retention. Thepatient will

    need toincrease fluids

    from her

    present intake(very low fluid

    intake). Input

    and outputmonitoring is

    beneficial inthis case.

    Pantoprazole(Protonix)

    Anti-ulcer agent

    Proton pumpinhibitor

    40mg1x daily

    9amIV

    Binds to anenzyme in the

    presence ofacidic gastric

    ph,

    preventingthe final

    transport ofhydrogen

    ions into the

    gastric lumen.

    Headache,abdominal pain,

    diarrhea,hyperglycemia.

    Patient hasGastro-

    esophagealreflux disease

    (GERD).

    Pantoprazoletreats heartburn

    symptoms andis indicated for

    erosive

    esophagusassociated with

    GERD.

    Assess patientroutinely for

    epigastric orabdominal pain

    and for frank or

    occult blood instool, emesis, or

    gastric aspirate.

    Medication ishaving the

    desired effectand the patient

    is not

    complaining ofGERD effects.

    The adverseside effect of

    hyperglycemia

    should benoted as a

    possiblecontributing

    factor for the

    patientspresent

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    BREAST CANCER 22

    hyperglycemic

    condition. The

    patient is notexperiencing

    any otheradverse side

    effects.

    Rosuvastatin

    Calcium

    (Crestor)

    Lipid loweringagent

    HMG-CoA

    reductase

    40mg

    1x daily

    BedtimeOral

    Inhibit an

    enzyme

    (HMG-CoAreductase),

    which isresponsible

    for catalyzingan early step

    in the

    synthesis ofcholesterol.

    Abdominal

    cramps,

    constipation,diarrhea, flatus,

    heartburn, rashes,rhabdomyolysis.

    Aid in the

    management of

    dyslipidemia.Patient has

    hyperlipidemia.

    Monitor liver

    function tests.

    May also causean increase in

    alkalinephosphatase

    levels and anincrease in

    bilirubin levels.

    Monitor patientfor muscle

    tenderness.

    Patient has

    hyperlidiemia.

    I do not havecholesterol

    values in toevaluate

    medicationeffectiveness.

    LDL, HDL,

    andtriglycerides

    must bemonitored.

    Patient is not

    experiencingadverse

    medicationeffects.

    Source: Deglin, J. H., & Vallerand, A. H. (2009).Daviss drug guide for nurses (11th

    ed.). Philadelphia, PA: F.A. Davis

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    Appendix B

    UNIVERSITY OF NORTH FLORIDA NURSING CARE PLAN FORM1. Nursing Diagnosis /

    Related to

    As Evidenced By:

    Acute Pain related to post double mastectomy procedure.

    Page # in

    Ackley &

    Ladwig

    601

    As Evidenced By:

    Subjective Objective

    Patient self-reported being in pain Described the pain as throbbing and

    stabbing

    Patient displays observable pain responsesincluding guarding of the breasts and crying.

    Respiratory rate 20 and heart rate of 98 beats perminute while at rest.

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    1. By the end of the 8 hour shift,

    patient will use a self-report paintool to identify current pain level

    and establish a comfort- function

    goal.

    1a. Conduct and document a

    comprehensive pain assessment.Determine location, temporal

    profile, aggravating and alleviating

    factors, and the effects that pain ishaving on the quality of life.

    Patient was fully assessed at thestart of the shift to determine a

    baseline for pain. She stated thatshe was in pain; the pain had

    lasted at least 2 hours, the pain

    radiated down her chest, and downher sides. She stated that it hurts

    the most when she moves, and she

    feels he best when she is layingstill with the head of the bed tilted

    at 30 degrees. Having pillowsunder each arm, propping the arms

    up to the level of the chest also

    alleviates some of the pain.

    1b. Assess pain level in patient

    using a valid and reliable self-

    report pain tool, such as the 0-10numerical pain rating scale. Thenurse posed this question to the

    patient, and explained that 0

    signifies no pain, while 10represents terrible pain. The

    patient state that she was at a level

    eight.

    1a. Determining the characteristic

    of pain is critical to determiningthe underlying cause of pain and

    effectiveness of treatment. Self-

    report is considered the singlemost reliable indicator of pain

    presence and intensity.

    1b. Single dimension pain ratings

    (such as the 0-10 pain scale) arevalid and reliable as measures of

    pain intensity level.

    1. Goal met. Patient

    was able to self-reporther pain on a 0-10

    numerical pain rating

    scale. She was alsoable to verbalize a pain

    level which wouldmake her more able to

    achieve activities of

    daily life.

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    2. By the end of the eight hourshift, the patient will report that a

    pain management regimenachieves comfort-function goal

    without adverse effects.

    1c. Ask the client to identify acomfort-function goal for a pain

    level on a self-report tool that

    would allow the patient to performnecessary activities easily. Patient

    stated that if her pain was at ornear a level 5, she would be able

    to perform activities, and would

    not fear movement as she

    currently does.

    2a. Manage acute pain using amultimodal approach. Patient had

    orders for Percocet oral 5mg as

    needed every four hours,Morphine 2mg IV as needed every

    four hours, and Nuerotin at 0900daily. The patient complained of

    pain and was given Percocet at0550 on Tuesday morning. At

    0900, the patient took Neurotin.

    At 1208 the patient self-reportedpain as a level 8 and was given

    Morphine 2mg IV. Morphine was

    administered again at 1600.

    1c. The relationship between panlevel and functional goals should

    be a major focus of the

    development of the individualizedpain management plan. Effective

    pain relief which allows functionand movement is critical for

    decreasing risk factors for

    cardiopulmonary andthromboembolic complications

    after surgery. Immobilization isalso a major risk factor for chronic

    hyperalgesic pain after surgery.

    2a. Multimodal analgesia

    combines two or more medicationsfrom different pharmacological

    classes that target different

    mechanisms along the painpathway. The advantage of this

    approach is that the lowesteffective dose of each drug can be

    administered, resulting in feweradverse side effects such as

    oversedation and respiratory

    depression.

    2. Goal met. At the endof the eight hour shift,

    the patient did notreport any adverse side

    effects from the pain

    medications. Thepatient was educated

    about the comfort-function balance, and

    medications and pain

    levels will continuallyneed reassessment, at

    least every four hours.

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    2b. Assess pain level, sedationlevel, and respiratory status at

    regular intervals during pain

    management with opioidadministration. Assess at least

    every four hours if patient hasbeen stable without episodes of

    hypoventilation. Patient vitals

    were taken and recorded everyfour hours by the student nurse.

    Eyes were examined and pupilswere equal, round, and reactive to

    light. Pupil size within normal

    limits. Respiratory rate remainedwithin normal limits. Patient was

    tested for orientation to date, time,place, and self every four hours as

    well and was oriented x4. Painlevel changed depending upon the

    activity level of the patient. Two

    hours after morphineadministration the patient self-

    reported her pain as a level 4. An

    hour later when the care teamassisted her in moving into the

    chair by the bed, she stated thather pain was increasing again due

    to the movement, and self-reportedher pain as a 7. Patient was given

    time to rest and we did not try to

    move her again for an hour. Shewas instructed to alert the

    2b. All patients receiving opioidsor pain management are at risk for

    sedation that may progress to

    oversedation and lead to clinicallysignificant opioid-induced

    respiratory depression.

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    3. By end of eight hour shift,

    patient will describenonpharmacological methods thatcan be used to help achieve

    comfort-function goal.

    healthcare team if she became

    dizzy, drowsy, or felt nauseas.

    3a. Support the patients use of

    non-pharmacologic methods to

    help control pain such as the useof distraction, imagery, and

    relaxation to aid in pain relief.The television was changed from a

    loud news entertainment program

    to a calm cooking show. Thelights in the room were dimed, and

    the door to her room was changedfrom being completely open to be

    approximately 90% closed. This

    environment was created in orderto provide calm and quiet, and to

    provide distraction from the painwithout creating barriers for

    relaxation.

    3b. Teach and implement

    nonpharmacological interventionswhen pain is relatively well

    controlled with pharmacologicalmethods. The nurse and student

    nurse practiced deep breathing

    with the patient. The methodconsisted of a slow, large

    inhalation, followed by pursed lip

    exhalation. The patient waseducated around moving at her

    3a. Cognitive-behavioral strategies

    can restore the patients sense ofself control, personal efficacy, andcan encourage active participation

    in her own care.

    3b. Nonpharmacological

    interventions should be used to

    supplement, not replace,pharmacological methods.

    3. Goal met. The

    patient was able toverbalize how tocommunicate her needs

    to the healthcare team.

    She stated that she feltmore comfortable

    telling the staff whenshe was feeling poorly.

    She admitted to feelings

    of hopelessness, and

    she cried talking abouthow she cant get up touse the bathroom. We

    discussed how feelings

    of hopelessness canmake a person feel

    physically bad.Recognizing that she

    can have some control

    over her environment

    and practicing copingmechanisms for pain

    may accelerate her

    healing process.

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    Ackley, B.J., & Ladwig, G.B. (2011).Nursing diagnosis handbook: A guide for planning care. (9

    th

    ed.). St. Louis, MO: Mosby.

    2. Nursing Diagnosis /

    Related to

    Impaired Skin Integrity related to obesity, immunological deficit post double

    mastectomy, immobility, impaired sensation.Page # in

    Ackley &

    Ladwig

    769

    As Evidenced By:

    Subjective Objective

    own speed and to alert caregivers

    if she is being hurt during an adult

    brief change. The patient wasencouraged to let others know

    when she was in pain so that

    caregivers can assist her.

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    Patient said she did not notice the twocuts on her right foot near her toenail.

    She stated that she does not wish toget out of bed.

    Patient is not eating. Stated she istired of hospital food, and that she

    doesnt like the way it tastes.

    Patient has type 2 DM. She has two cuts on her right foot. There is a stage 2 pressure ulcer on her left

    buttock.

    Patient has two openings in skin for JP drains toaid in eliminating fluid post double mastectomy.

    She is not ambulatory. Patient is wearing an adult brief for urinary

    incontinence.

    Patient age is 73.

    Outcome Indicators (NOC) Nursing Activities (NIC)

    Rationale

    (from nursing references) Evaluation andRevision of Plan

    1. Maintain integrity of skinsurface surrounding JP drains,

    right foot, and left buttock during

    an eight hour nursing shift.

    1a. Assess site of skin impairmentand determine cause. Wounds on

    buttock are pressure ulcers.

    Wounds on sides of breasts are

    from incisions during themastectomy. The wounds on her

    foot are from an unknown source.

    1b. Monitor site of skinimpairment at least Q12h for

    changes in color, redness,

    1a. Cause of the wound must bedetermined before interventions

    can be implemented. This is the

    basis for additional testing and

    evaluation to start the assessmentprocess.

    1b. Systematic inspection can

    identify impending problems

    early.

    1. Goal met. Sites weremonitored throughout

    shift; client stated that

    she experienced no

    change in sensation.

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    swelling, warmth, or other signs of

    infection. Determine if the client

    is experiencing changes insensation. The wounds were

    examined at the start and end of an

    eight hour shift.

    1c. Select a topical treatment thatwill maintain a moist wound-

    healing environment and that isbalanced with the need to absorb

    exudate. Client treated with

    Sensicane on her buttock; Versiva

    sterile wound dressing protectedthe ulcer on her buttock. Thesuture site and around her JP

    drains was kept clean and dry.

    Dry gauze dressings with Silvadinsecured with tape are around the

    JP drainage tubes. The cuts on herfoot were cleaned with saline and

    left open to air.

    1c. Choosing dressings that

    provide a moist environment, keep

    periwound dry, control exudateand eliminate dead space to

    promote wound healing.

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    2. By end of eight hour shift,

    client will demonstrateunderstanding of plan to heal skin

    and prevent injury.

    2a. Implement an incontinence

    management plan to preventexposure to chemicals in urine and

    stool that can erode or strip theskin. The patient was assessed

    every hour and was asked if she

    wanted to get up and use thebedside commode. She was asked

    to call the nurse immediately if sheurinated in the adult brief so that

    the brief could be changed. She

    was also offered the bed pain for

    bowel movements.

    2b. Maintain the head of the bed atthe lowest possible degree of

    elevation.

    2c. Assess the clients nutritional

    status. The patient was refusing to

    eat because she was did not likethe taste of the food. She ate

    approximately one scrambled eggfor breakfast and did not eat any

    lunch. We discussed this with her

    2a. Implementing a plan with the

    use of a skin protectant cansignificantly decrease skin

    breakdown and pressure ulcer

    formation.

    2b. Lowest possible elevation willaid in the reduction of sheer and

    friction.

    2c. Optimizing nutritional intake,including calories, fatty acids,

    protein, and vitamins, is needed to

    promote wound healing.

    2. Ongoing. Client was

    able to verbalize theimportance of changing

    her brief andeliminating the

    moisture after the brief

    becomes soiled. Shestated that she would

    use the call bell forassistance, and she did

    perform that action.

    She stated that sheknew why the head of

    the bed should be at alow angle to prevent

    excess pressure on her

    buttock, although shedid not always keep it

    there because it made itdifficult to see the

    television. She statedthat she has requested

    that her daughter bring

    her food from home;her daughter would be

    bringing her dinner.

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    doctor; her doctor stated that food

    from outside of the hospital is

    permitted if she feels like a changeof menu would perk her appetite.

    We discussed the importance of

    eating in order to support healing.

    Ackley, B.J., & Ladwig, G.B. (2011).Nursing diagnosis handbook: A guide for planning care. (9th

    ed.). St. Louis, MO: Mosby.

    3. Nursing Diagnosis Risk for falls

    Risk factors: cluttered environment, unfamiliar room, polypharmacy, impaired

    balance, neuropathy, post-operative condition.

    Page # in

    Ackley &

    Ladwig

    355

    Ackley, B.J., & Ladwig, G.B. (2011).Nursing diagnosis handbook: A guide for planning care. (9th

    ed.). St. Louis, MO: Mosby.

    As Evidenced By:

    Subjective Objective

    Patient stated that she is feeling tired,weak, and has been dizzy at times.

    She is not able tolerate weight bearingactivity.

    Patient is taking 2mg Morphine as neededQ2h for pain, and 5mg Ditropan. Both

    medications have a possible side effect of

    dizziness.

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    Stated that this was the first day thatshe felt that she was not able to

    support her own body weight for

    ambulation.

    Cluttered environment in an unfamiliarand dimly lit hospital room.

    Patient is anemic. Patient has peripheral neuropathy

    secondary to type 2 DM.

    Outcome Indicators (NOC) Nursing Activities (NIC)

    Rationale

    (from nursing references) Evaluation and

    Revision of Plan

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    1. Client will remain free of falls

    for an eight hour shift.

    1a. Use a high-risk fall armband

    and Fall Room sign to alert stafffor increased vigilance and

    mobility assistance. Place the calllight and fluids in reach of the

    patient. Encourage the patient to

    call the nurse as much as neededto assist with toileting, or getting

    items for the patient.

    1b. Screen for balance andmobility skills (supine to sit,

    sitting supported and unsupported,

    sit to stand). Patient was able tomove from supine to sitting

    supported and unsupported. She

    did not feel comfortable placingany weight on lower extremities.

    Student nurse and patient care techassisted the patient to a wheelchair

    to change position. Patient criedand stated that she was unable to

    feel her legs.

    1c. Evaluate client for mental

    health and neurologic function.Tested patient for orientation in

    relation to time, place, self, andlocation. Client was able to

    explain a metaphor.

    1a. These steps alert the nursing

    staff of the increased risk for falls.Placing the call light in reach of the

    patient and creating an environmentwhich encourages communication

    prevent the patient from needing to

    ambulate without assistance.

    1b. It is helpful to determine the

    clients functional abilities and thenplan for ways to improve problem

    areas or determine measures to

    improve safety.

    1c. Mental health status has beenfound to significantly influence the

    rate of falls.

    1. Nursing activities

    implemented. Plan met;at the end of eight hour

    shift, the patient did not

    have any falls.

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    Ackley, B.J., & Ladwig, G.B. (2011).Nursing diagnosis handbook: A guide for planning care. (9th

    ed.). St. Louis, MO: Mosby.

    2. By the end of eight hour shift,

    client will be able to recognize an

    environment which minimizes the

    risk of falls.

    2a. Place a fall prone patient in a

    room that is near the nursing

    station.

    2b. Teach patient to assess forhazards to increase safety

    including eliminating clutter,

    slippery floors, scatter rugs, andother potential hazards. Even

    though she was unable to stand atthis time, the patient stated that

    she generally ambulates to the

    bathroom or the bedside

    commode.

    2c. Thoroughly orient client to

    environment. Keep the bed in thelow and locked position. Place the

    call light within reach and showhow to call for assistance. Explain

    that nurse will answer call lightpromptly. Personal items were

    placed near the patient, as well.

    2a. Such placement allows more

    frequent observation of the client.

    2b. Clients suffering from impairedmobility are at risk for injury from

    common hazards.

    2c. Limiting the need for the patient

    to get out of bed unassisted willlower the likelihood that the patient

    will incur injuries due to a fall.

    2.Goal met. Patient

    was able to verbalize

    the need for a clean andclutter free room. She

    used her call light

    several times during theshift, and was able toverbalize the best

    placement for furniture

    and medical equipmentin her hospital room.

    The room was

    repositioned, and clientstated that she would

    tell the next shift of

    healthcare membershow the room should bekept for her safety. Her

    room however, was not

    changed.

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    4. Nursing Diagnosis /

    Related to

    Imbalanced Nutrition: less than body requirements related to loss of appetite as

    evidenced by aversion to eating, lack of interest in food, and reported altered taste

    sensation.

    Page # in

    Ackley &

    Ladwig

    575

    As Evidenced By:

    Subjective Objective

    Patient stated that she is not hungry. Patient stated that food seems to have

    no taste. Patient is refusing to eat the meals in

    the hospital.

    Low electrolyte lab values: potassium (3.5),glucose (58), total protein (6.2), albumin (1.6),

    calcium (8.1), magnesium (1.6)

    Complete blood count low levels: red blood cells(2.92), hemoglobin (7.8), hematocrit (24.2).

    Outcome Indicators (NOC) Nursing Activities (NIC)

    Rationale

    (from nursing references) Evaluation and

    Revision of Plan

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    1. During the eight hour shift,

    patient will consume adequate

    nourishment.

    1a. Monitor food intake and record

    percentages of food that is eaten.

    Keep a three day food diary andconsult with a dietitian to establish

    a minimal calorie intake. The

    nurse and student nurse madenotes about the food intake for thefirst day. Patient ate only a

    scrambled egg for breakfast and

    did not eat any lunch. She wasoffered snacks as well, but

    declined them also. The nurse

    stated that she would put in anorder for the dietitian to meet with

    the patient concerning intake.

    1b. A nurse must make food

    available as desired between earlyevening and breakfast. The patient

    was offered graham crackers andpudding as snacks after lunch.

    The snacks were declined. The

    doctor was consulted and the

    patient may have a family memberbring foods from home which may

    trigger an appetite.

    1c. Work with the patient todevelop a plan for increased

    activity. The patient was moved

    from laying to supported sitting,and then to unsupported sitting.

    1a. Use of a food diary is helpful

    for the patient and the nurse, to

    examine food eaten, patterns ofeating, and presence of

    deficiencies in the diet.

    1b. Having food available as

    desired can increase nutritional

    intake.

    1c. Immobility leads to negative

    nitrogen balance that fosters

    anorexia.

    1. Ongoing. The food

    intake journal was

    started, but will needentries over three days

    to establish a pattern.

    Additionally, thedietitian had not yetconsulted with the

    patient. The patient is

    having a familymember bring in snacks

    and favorite food items.

    It will be important tonote if the new food

    selections can prompt

    an increase in intake.The patient was notcurrently able to

    participate in long

    periods of activity.Building the length of

    time in which she isactive may encourage

    the patient to eat.

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    2. By the end of the eight hour

    shift, the patient will identify fluid

    and nutritional requirements.

    The patient was then transferred

    into the wheelchair. The patient

    stated that these activities took alot out of her. She was given

    time to rest and relax in the chair

    before transferring back to the bed.The nurse assured that the patientwould be in the bed sitting and

    resting at least 30 minutes before

    lunch was served.

    2a. Recognize that patients with

    wounds and a recent surgery need

    increased calories to maintainnutrition. The nurse and studentnurse discussed the importance of

    protein in the diet, and linked it to

    wound healing. The patient thendescribed her desire for her

    wounds from her doublemastectomy to heal quickly.

    Patient education around protein

    allowed the patient to make aconcrete connection between diet

    and health.

    2b. Assess intake calcium andvitamin D. Teaching centered on

    the purpose of calcium for bonestrength. The patient was

    2a. An increase in nutrient and

    protein rich nutrition encourages

    faster healing.

    2b. The elderly adult needs

    1200mg calcium and a minimum

    of 800IU of vitamin D daily.

    2. Ongoing. The

    patient was able toidentify reasons to eat

    protein and calcium richfoods; she did not eat

    the foods. She took

    sips of her fluids, butnever reached the

    10mL/hour goal. Shestated that she didnt

    like to go to the

    bathroom because shewas wearing an adult

    brief and she didnt likegetting it wet. She also

    felt as though she did

    not have the strength togo to the commode, so

    she did not want to eat.The nurse and student

    nurse made a plan to

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    educated about the importance of

    eating dairy, and was then able to

    explain why dairy products are animportant part of the diet. The

    patient was then offered pudding.

    The pudding was declined.

    2c. Assess for factors contributingto an acute illness, such as

    dehydration. The patient was not

    drinking water or ginger ale. Thepatient was given a fluid

    challenge. The patient wasencouraged to drink a minimum of

    10 ounces of fluid an hour. While

    this would still be under her fluidrequirement, it would be a marked

    improvement over the patientscurrent status. Drinks were poured

    by the student nurse, and duringthe hourly rounds the amount of

    fluid drank was noted. The patient

    was also encouraged to eat foodsthat were high in fluid, such as

    green beans.

    2c. Elderly individuals need at

    least 1600mL/day to ensure

    adequate hydration.

    encourage use of the

    brief, and to assist the

    patient with self-esteem. The issues with

    going to the bathroom

    must be rectified beforethe patient can feelcomfortable eating the

    proper amount of food

    to maintain adequate

    nutrition.

    Ackley, B.J., & Ladwig, G.B. (2011).Nursing diagnosis handbook: A guide for planning care. (9th

    ed.). St. Louis, MO: Mosby.