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© Cancer Research UK 2006 Registered charity number 1089464 The statistics in this presentation are based on the Bowel CancerStats report published in 2007. However, the incidence, mortality and survival statistics have been updated to reflect the latest available data. For more information about UK cancer statistics please contact [email protected] or visit http://info.cancerresearchuk.org/cancerstats Bowel Cancer

Bowel Cancer

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Bowel Cancer. The statistics in this presentation are based on the Bowel CancerStats report published in 2007. However, the incidence, mortality and survival statistics have been updated to reflect the latest available data. - PowerPoint PPT Presentation

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Page 1: Bowel Cancer

© Cancer Research UK 2006 Registered charity number 1089464

The statistics in this presentation are based on the Bowel CancerStats report published in 2007. However, the incidence, mortality and survival statistics have been updated to reflect the latest available data.For more information about UK cancer statistics please contact [email protected] or visit http://info.cancerresearchuk.org/cancerstats

Bowel Cancer

Page 2: Bowel Cancer

© Cancer Research UK 2006 Registered charity number 1089464

Figure One: Percentage distribution of cases by site within the large bowel, England, 1997-2000

Page 3: Bowel Cancer

© Cancer Research UK 2006 Registered charity number 1089464

Table One: Numbers and rates of new cases of bowel cancer, by sex, UK by country, 2006

  England Wales Scotland N.Ireland UKCases                    Males 16,778 1,214 1,875 563 20,430Females 14,012 957 1,635 480 17,084Persons 30,790 2,171 3,510 1,043 37,514

Crude rate per 100,000 population            

Males 67.3 84.0 75.9 66.0 68.8Females 54.2 62.9 61.8 54.0 55.3Persons 60.7 73.2 68.6 59.9 61.9Age-standardised rate (European) per 100,000 population    Males 54.9 61.8 61.3 62.9 56.0

95% CI 54.1 55.8 58.3 65.3 58.5 64.0 57.7 68.1 55.3 56.8

Females 36 39.1 40.4 41.1 36.495% CI 35.1 36.3 36.6 41.6 38.4 42.3 37.4 44.7 35.9 37.0

Persons 44.4 49.4 49.4 50.8 45.395% CI 43.9 44.9 47.3 51.5 47.8 51.1 47.7 53.9 44.8 45.7

Page 4: Bowel Cancer

© Cancer Research UK 2006 Registered charity number 1089464

Figure Two: Numbers of new cases and age-specific incidence rates for bowel cancer, by sex, UK, 2006

Page 5: Bowel Cancer

© Cancer Research UK 2006 Registered charity number 1089464

Table Two: Numbers and rates of new cases for colon and rectal cancer, by sex, UK, 2006

   Number of

casesCrude rate per

100,000 population

Age-standardised rate (European) per 100,000

population

Colon Males 12,005 40.4 32.5

  Females 11,379 36.8 23.7

Rectum Males 8,425 28.4 23.6

  Females 5,705 18.5 12.7

Page 6: Bowel Cancer

© Cancer Research UK 2006 Registered charity number 1089464

Figure Three: Age-standardised* incidence rates for colorectal cancer, by sex, region of England, England, Scotland, Wales, Northern Ireland and Ireland, 1991-99

* to European standard population * to the European standard population

Page 7: Bowel Cancer

© Cancer Research UK 2006 Registered charity number 1089464

Figure Four: Age-standardised* incidence rates for bowel cancer, by sex, EU, 2006 estimates

* to European standard population * to the European standard population

Page 8: Bowel Cancer

© Cancer Research UK 2006 Registered charity number 1089464

Figure Five: Age-standardised* incidence rates for colorectal cancer, by sex, world regions, 2002 estimates

† to World standard population * to the European standard population

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© Cancer Research UK 2006 Registered charity number 1089464

Figure Six: Age-standardised (European) incidence rates, bowel cancer, by sex, UK, 1993-2006

* to European standard population

Page 10: Bowel Cancer

© Cancer Research UK 2006 Registered charity number 1089464

Figure Seven: Household food consumption, Great Britain, 1974-2000

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© Cancer Research UK 2006 Registered charity number 1089464

Figure Eight: The number of portions of fruit and vegetables eaten per day by adults aged 16 and over, England, 2004

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© Cancer Research UK 2006 Registered charity number 1089464

Figure Nine: Trends in bodyweight, by sex, England, 1995 and 2004

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© Cancer Research UK 2006 Registered charity number 1089464

Table Three: Staging of colorectal cancers

UICC/TNM Modified Dukes'

Stage 0 Carcinoma in situ A

Stage I No nodal involvement, no distant metastasis  

  Tumour invades submucosa (T1, N0, M0)  

  Tumour invades muscularis propria (T2, N0, M0)  

Stage II No nodal involvement, no distant metastasis B

  Tumour invades into subserosa (T3, N0, M0)  

  Tumour invades into other organs (T4, N0, M0)  

Stage III Nodal involvement, no distant metastasis C

  1 to 3 regional lymph nodes involved (any T, N1, M0)  

  4 or more regional lymph nodes involved (Any T, N2, M0)

Stage IV Distant metastasis (any T, any N, M1) D

Page 14: Bowel Cancer

© Cancer Research UK 2006 Registered charity number 1089464

Figure Ten: Age-standardised* one-year relative survival rate, colon cancer, by sex, England and Wales 1971-2006

* to the European standard population

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© Cancer Research UK 2006 Registered charity number 1089464

Figure Eleven: Age-standardised* one-year relative survival rate, rectal cancer, by sex, England and Wales, 1971-2006

* to the European standard population

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© Cancer Research UK 2006 Registered charity number 1089464

Figure Twelve: Age-standardised* five-year relative survival rate, colon cancer, by sex, England and Wales, 1971-2006

* to the European standard population

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© Cancer Research UK 2006 Registered charity number 1089464

Figure Thirteen: Age-standardised* five-year relative survival rate, rectal cancer, by sex, England and Wales, 1971-2006

* to the European standard population

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© Cancer Research UK 2006 Registered charity number 1089464

Table Four: Approximate frequency and five-year relative survival (%) by Dukes' stage

Dukes' Stage at diagnosis   Percentage of cases Five-year relative survival       A 8.7% 93.2%B 24.2% 77.0%C 23.6% 47.7%D 9.2% 6.6%

Unknown   34.3% 35.4%

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© Cancer Research UK 2006 Registered charity number 1089464

Table Five: Number of deaths and mortality rates, colorectal cancer, UK, 2007

  England Wales Scotland N.Ireland UKDeaths                    Males 6,878 525 822 249 8,474Females 6,171 431 741 190 7,533Persons 13,049 956 1,563 439 16,007Crude rate per 100,000 population            Males 27.4 36.1 33.1 28.9 28.3Females 23.8 28.2 27.9 21.2 24.3Persons 25.5 32.1 30.4 25.0 26.3Age-standardised rate (European) per 100,000 population    Males 21.3 25.7 25.8 26.8 22.1

CI 95% 20.8 21.8 23.5 27.9 24.0 27.5 23.5 30.1 21.6 22.5

Females 13.8 15.7 16.2 14.8 14.1CI 95% 13.4 14.1 14.2 17.2 15.1 17.4 12.7 16.9 13.8 14.5

Persons 17.2 20.2 20.3 20.1 17.7CI 95% 16.9 17.5 18.9 21.5 19.3 21.3 18.2 22.0 17.4 18.0

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© Cancer Research UK 2006 Registered charity number 1089464

Figure Fourteen: Percentage decrease in mortality rates, by age and sex, bowel cancer, UK, 1998-2007