BME-Undergrad Advising Handbook

Version F10

BME Undergraduate Program

Handbook

Note: The handbook is updated every year. We recommend students

and faculty always using the latest version of the handbook.

(For use in the Fall 2010 Semester)

DUKE BIOMEDICAL ENGINEERING education • research • technology

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Highlights of Important Changes

1. Changes in course requirements

• Biology 101L is required for all BME single or dual majors as the first life science course starting with matriculating class of 2010. AP credit can not be used in lieu of Biology 101L.

• To fulfill the physiology requirement (starting with matriculating class of 2010), all BME single or dual majors must take one of the following three courses:

BME 201L Electrophysiology BME 207 Transport Phenomena in Biological Systems an approved BME quantitative physiology elective as LS elective (Table 7a)

• ME 83L is required for all BME single or dual majors.

• EGR 75L is required for BME single or dual majors. EGR 75L is a prerequisite for ME 83L.

• Approved physiology electives (in lieu of life science electives) for ME/BME and ECE/BME are listed in Table 7a.

• 153L is equivalent to ECE 27L only for ECE/BME dual majors

• The total number of Math courses taken at Duke plus the number of AP or transfer credits must equal 5 starting from 2008 matriculants.

• 50% of BME electives taken (as part of graduation requirement) must be 200+ level starting from 2007 matriculants.

2. Changes programs and majors

• The new BME curriculum takes effect starting with 2008 matriculants.

• 4 + 1 BSE/MS Program

3. Miscellaneous • A student’s advisor may vary from semester to semester for various reasons (e.g., faculty

on sabbatical and the arrival of new faculty). Thus, students need to check their academic information every semester before making an appointment.

• The address of BME website for making an online appointment is http://advising.pratt.duke.edu/

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Table of Content

Introduction …………………………………………………………………………………… 4

Mission ……………………………………………………………………………………..… 4

Program Objectives …………………………………………………………………………… 5

Pratt School of Engineering and BME Major Requirements…………………………..……… 5

Independent Study and Pratt Research Fellow Program ……….…..……….…..…..……….…. 8

Graduation With Distinction ….…..……….…..……….…..……….….….…..……….…..…… 8

Preparation for Medical School ………………………………………………………..……… 9

Dual Major, Second Major, Minor, And Certificate Programs …………….……….....…… 10

4 + 1 BSE/MS Program ………………………………………………………………………. 10

Advising …………………………………………………………………………………….. 10

Information on Internship, Co-Op, Employment, and Graduate School Opportunities …….…. 11

Appendix

Tables 1-6: Samples of BME Major And Its Related Dual-Major Curricula …..……… 13

Table 7. List of Approved Life Science elective Courses ………………...…………... 25

Table 7a. List of Approved Physiology Courses …………………………………...…. 27

Table 8. List of Approved Biomechanics Elective Courses For BME/ME Dual Major…. 28

Table 9. BME Area Electives Currently Offered ……………………………………….. 29

Additional Information on Courses ……………………………………………….… 30

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Introduction This handbook provides an overview of the undergraduate program in Biomedical Engineering (BME) at Duke University. It covers the program mission, educational objectives, major requirements, dual major options, and course requirements for students planning to apply for medical school, and research opportunities. The undergraduate major in BME at Duke University is one of the first accredited programs in the United States, and is consistently rated as one of the best BME programs in the nation. In addition, BME is the most popular major in the Pratt School of Engineering and one of the most popular undergraduate majors in the University. The student population is diverse both geographically and culturally, and is a cross-section of the very best students in the nation and from around the world. The training in the program emphasizes research and project-based learning which prepares our students with the necessary skills for successful entry into industry and professional schools (e.g., graduate school and medical school). The members of the BME department associated with the undergraduate program are:

Director of Undergraduate Studies Professor Patrick Wolf 1149 FCIEMAS Tel: 660-5114 Email: [email protected]

Associate Director of Undergraduate Studies Professor Aura Gimm 254 Engineering Annex Tel: 660-8267 Email: [email protected]

Staff Assistant for the Undergraduate Program Susan Story 136 Hudson Hall Tel: 660-5133 Email: [email protected] Mission The general mission of the Department of Biomedical Engineering, as part of Duke University, is to (i) prepare our students for lives of skilled and ethical service to their communities by creating a free and open learning environment that fosters their intellectual growth, (ii) advance the frontiers of scientific inquiry, and (iii) contribute with distinction to the international community of scholarship. As biomedical engineers, our unique mission is to (a) create enabling technologies for the improvement of human health and health care and (b) create new knowledge at the interface between engineering and biomedical science. We work closely with biologists and clinicians to identify important problems that impact human health and solve them using our technical expertise. We engage motivated and talented students in the classroom, laboratory, and clinic, imparting to them the spirit of our mission as we prepare them for future careers as effective, knowledgeable, and ethical leaders in corporate, professional, and academic communities.

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Program Objectives We expect that graduates of our program are prepared:

(I) to be leaders in biomedical engineering or related areas in industry, academia, and medicine

(II) to undergo intellectual growth, and to be effective in free and open inquiry (III) to engage in life long learning and receive advanced degrees or training for

professional advancement (IV) to utilize experience integrating mathematics, engineering, life science, and

design to address complex problems (V) to understand the social and ethical implications of their work

The outcomes from the BME program at Duke University are characterized by the following capabilities of our students:

(1) Apply mathematics, science, and modern engineering tools to identify and solve problems at the interface between engineering and biology.

(2) Design experiments and acquire, analyze, and interpret data from living systems using modern engineering tools.

(3) Work in multidisciplinary teams to design within realistic constraints and evaluate components, systems or processes in the characterization of biomedical phenomena.

(4) Have the broad education necessary to address ethical, professional, and societal problems associated with the interactions between biological and non-biological systems.

(5) A recognition of the need to engage in advanced study, life-long learning, and be aware of current issues in biomedical engineering.

(6) Communicate effectively. Pratt School of Engineering and BME Major Requirements As a program accredited by the Accreditation Board of Engineering and Technology (ABET), the BME curricula must satisfy minimum requirements in mathematics, sciences, and engineering. In addition, the Pratt School of Engineering has requirements for all engineering students. To meet these constraints, the Department of Biomedical Engineering has developed specific requirements for undergraduate students. Samples of curricula for students with different BME-related major choices are provided in Tables 1-6. In summary, BME students need to take the following courses. Two Biology Courses and Physiology Requirement – (For matriculating classes < 2010) Biology 25L or AP credit in Biology (Biology 19) is required for all BME single or dual majors. The second course can be selected from Table 7. (For matriculating classes 2010) Biology 101L is required for all BME single or dual majors. AP credit can not be used in lieu of Biology 101L. The second course can be selected from Table 7. In order to fulfill a requirement for physiology within BME, students must take one of the following three courses:

1) BME 201L Electrobiology (See BME Required Courses below) 2) BME 207 Transport Phenomena in Biological Systems (See BME Required Courses below) 3) An approved BME Quantitative Physiology Elective (Table 7a)

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Two Chemistry Courses – (For matriculating classes < 2009) Most students take Chemistry 21L and 22L. AP credit (Chemistry 19) is accepted in place of Chemistry 21L. To fulfill the other chemistry requirement, students can take either Chemistry 22L, Chemistry 23L, or Chemistry 151L. (For matriculating classes 2009) Students are required to have Chem 19(AP-5) or to take Chem 31L or Chem 43L AND take Chem 32L or Chem 151L. Chemistry options: If no AP or AP<4: Chem 31L, Chem 32L or Chem 31L, Chem 151L If you have Chem 18(AP-4): Chem 43L, Chem 32L or Chem 43L, Chem 151L If you have Chem 19(AP-5): Chem 32L or Chem 151L Two Physics Courses – The choices are as follows. • Physics 61/62: • Physics 41/42: for students transferring from the Trinity College.

For premed students who take the Physics 61/62 sequence, it is highly recommended that you also take Physics 63 because Physics 61 and 62 do not cover all the materials in the MCAT. AP credits are accepted in place of the physics requirements (Physics C Exams on mechanics for

Physics 61L and electricity and magnetism for Physics 62L, respectively). If students use AP credits for both courses, they must take Physics 63 or Physics 143. Students may not take Physics 61 at Duke and use AP credit for Physics 62.

Physics options: If no AP credit or AP<4: Physics 61L, Physics 62L If you have Physics 61 (AP 4,5): Physics 62L If you have Physics 61 and 62 (AP 4,5): Physics 63L

Five Mathematics Courses – Math 31, 32, 103, 107, and 108. Students wishing to do a BME/Math dual-major, will need to take Math 31, 32, either (103/104) or (104/105), 131 and 133 (104/131 substituting for 107, and 133 substituting for 108). AP credits can be used for Math 31 and 32, although it is recommend that AP credit be used only for Math 31. Common questions about mathematics placement are answered at the website: http://www.math.duke.edu. Transfer credits are examined on an individual basis. (For matriculating classes < 2008) If students are advised by the math department to skip any math requirements listed above, they must receive grades equal to or better than B- in all subsequent math courses, including the statistics course. In addition, the total number of math and natural science courses taken at Duke plus the number of AP credits for these courses must be 9. (For matriculating classes 2008) If students are advised by the math department to skip any of the math courses listed above, they must replace those courses with additional Math (not Stat) courses approved by the BME DUS. The total number of Math courses taken at Duke plus the number of AP or transfer credits must

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equal 5. (Approved classes include: Math 132S, 133, 160S, 181, 216; CE 202; Math 135 AND Math 136 combined can be used in lieu of one Math class and Stat 113) One Statistics Course – Stat 113. All BME single and dual majors must take Stat113 with the exception of students with second major or a minor in mathematics; these students may take both Math 135 and 136 in lieu of Stat 113 (see note above). Digital Computation and Computer Programming: All engineering students must take EGR 53 to meet this requirement. Students with BME/ECE dual major must also take CPS 100. Five Social Sciences and Humanities (SSH) Courses – The specific requirements are as follows. • At least one course must be a social science (SS). • Other courses must be selected from at least two of the following three areas: arts, literature,

and performance (ALP), civilization (CZ), and foreign language (FL). • At least two courses must be taken from the same department with one being at 100-level or

higher. • Skill courses cannot be used to fulfill the SSH requirements. • A maximum of two AP credits are accepted in place of the SSH requirements. One Undergraduate Writing Course – Writing 20 is required. BME Required Courses for matriculating classes < 2008 – For students in the BME major, the following nine courses are required: BME 83L, 100L, 101L, 110L, 153L, 154L, 171, 207 and a BME design course. The design course can be chosen from the following list:

BME 227L Design in Biotechnology (typically offered every term) BME 236L Biophotonics Instrumentation (typically offered in Spring) BME 260L Devices for People with Disabilities (typically offered every term) BME 262L Design for The Developing World (typically offered every term) BME 264L Medical Instrument Design (typically offered in Fall)

BME Required Courses for 2008 matriculants and beyond– For students in the BME major, the following nine courses are required: BME 83L or ME 83L, BME110L or EGR 75L, BME 100L, BME 153L, BME 154L, 171 or ECE 54L, two BME Area Core Classes, and a BME design course (listed above). The two Area Core Classes are chosen from the following list:

BME 201L Electrophysiology (EL) BME 202L Fundamentals of Biomaterials and Biomechanics (BB) BME 207 Transport Phenomena in Biological Systems (MC) BME 233 Modern Diagnostic Imaging Systems (IM)

BME Electives – Students take elective courses to learn advanced knowledge in specific areas of biomedical engineering. More than thirty BME electives have been developed, but the courses offered in any given semester depend on the availability of faculty. The number of BME electives that the students need to take depends on their major choices (see Tables 1-6). It is

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strongly recommended, that in order to insure adequate depth in a subject area, all students take at least 50% of their electives at the 200 level (required for 2007 matriculants). BME Electives for 2008 matriculants and beyond – Students must take two BME Area Elective courses within the same Area (EL, BB, MC, or IM). The number of BME general electives required will depend on the major (two for BME). See Table 9 for the current list of Area Electives. Unrestricted Electives – At most, two unrestricted elective course credits will be counted. The final number is dependent on the major choice (see Tables 1-6). Notes for 2008 matriculants and beyond – In the spring semester of your junior year you will take two BME Area Core Classes. These courses will NOT be offered in the Fall semester so you will not be able to graduate on time if you do not take these courses in this semester. Students studying abroad should plan to go abroad in the Fall semester of their junior year. It will be EXTREMELY difficult to go abroad for Spring semester of your junior year and to graduate on time. To insure depth in at least one area of Biomedical Engineering, you must take three classes in that area (One core class and two area elective classes). The areas are: 1) Electrobiology (EL), 2) Biomaterials and Biomechanics (BB), 3) Molecular Cellular and Tissue Engineering(MC), and 4) Imaging and Measurement Systems(IM). In the Spring semester of your Junior year, you will take the Core classes for two of these areas. The Area Core classes are listed above. In your senior year you must take two electives from one of the two Areas you selected as a Junior. Table 9 lists the approved electives for each Area. Your final two BME electives (for BME single majors) can be any BME elective course for which you have the perquisites, including independent study. These can include the Area Core classes you did not take as a junior. Independent Study and Pratt Fellow Program Independent study is an integral and immensely popular component of the undergraduate education at Duke. Up to two such courses (during junior and senior years only) can be counted as BME electives (BME 191, 192) depending on the choice of major. A research experience can be achieved in one of three ways. The first mechanism is to take independent study courses performing directed BME research with a BME faculty member. The second mechanism is to undertake an Independent Study with a non-BME faculty member (for instance a clinician). In such cases, the project must be sponsored by a BME faculty member. The sponsor is responsible for evaluating the quality of project and the performance of student. Some students choose to perform sponsored BME research in the Duke Smart House Program (For details, check the website at http://delta.pratt.duke.edu/). The third mechanism for undertaking Independent Study is to apply for a Pratt Research Fellow position during your junior year (For details, please send emails to Martha Absher, the director of the program or check the website at http://www.pratt.duke.edu/pratt-research-fellow). Pratt Research Fellows perform research in a BME faculty’s lab for three academic semesters plus a full summer term and receive two BME elective credits (BME 191 and 192). Graduation With Distinction Graduation with Distinction Award is presented to the Pratt students who, in the opinion of the BME Department and a special committee of the faculty, have demonstrated exceptional achievement in the areas of their special interest by conducting independent research and presenting the research project with a distinguished piece of writing and/or a poster presentation.

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BME students, who have final grade point average of 3.5 or higher and have taken BME 191 through either an independent study or the Pratt Research Fellow Program are eligible to apply for the Award (For details, email the BME DUS). All students, who graduate in December and want to apply for Graduation with Distinction, should present the research project in the symposium held in April in the year prior to graduation. Preparation for Medical School While the following information is thought to be correct, students should use the Health Professions Advising (HPA) at Duke as their primary source for Medical School requirements and advice. Entrance to medical and dental schools in the United States requires the student to take the following courses: Course Duke Equivalent English 1 yr WRITING 20 and one ENGLISH or LIT course Chemistry (Intro) 1 yr with lab CHEM 21L/22L or CHEM 23L or CHEM 31L/32L Organic Chemistry 1 yr with lab CHEM 151L/152L Physics 1 yr with lab PHYSICS 61L/62L* or 41L/42L Biology 1 yr with lab Two BIOLOGY courses with labs Biochemistry 1 term BIOCHEM 227, not all schools require biochemistry * See also Physics requirements for all BME students described above. Some courses can be used to satisfy the requirements for both the BME major and the entrance to medical and dental schools. They include:

1. Writing 20 and an English or Literature course. 2. Biology 25L (not offered starting Fall 2010) or Biology 101L satisfies one of the two

biology requirements. However, students who receive AP credit, Biology 19, in place of Biology 25L, will still need to take two biology courses with labs or one biology course

with a lab plus another biology course without a lab. In the latter situation, students need to

take BME 101L or 201L since its lab portion has been accepted as one of the biology lab

requirements by most medical and dental schools. Please also note that the lecture portion

of BME 101L or 201L does not count as a biology course. 3. A student’s two Unrestricted Electives can be used to take Organic Chemistry I&II (Chem

151L&152L) during the sophomore and junior years. 4. Many but not all medical schools require a semester of biochemistry (BIOCHEM 227).

This course can be used to satisfy Life Science Elective requirement for BME degree. Note, however, BIOCHEM 227 does not have a lab.

Students planning to attend medical and dental schools should also consult with their advisors about course planning. The sample schedule shown in Table 1b/2b/3b is one example for pre-med and BME. Some students find it is easier to complete all of their MCAT related courses prior to the summer between their sophomore and junior year. This allows the MCAT to be taken in the summer. Moving the exam to the summer permits more preparation time. Pre-med students should consult with their advisor and the Office of Health Professions Advising (HPA) about course planning. HPA is located at 011 Allen Building (the website is

http://prehealth.duke.edu). The center provides advices to students planning careers in health

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professions and also information on application process, degree requirements, research and volunteer opportunities. Dual Major, Second Major, Minor, And Certificate Programs To obtain depth in specific BME areas, students can declare a dual major within the Pratt School of Engineering. For these students, the required courses are listed in Tables 3-6. Opportunities also exist for students with AP credits to combine the BME major with a second major, minor, or certificate from the Trinity College. (A certificate is similar to a minor but offered for interdisciplinary study.) To do so, the students must meet the same requirements as those for BME single major plus the specific requirements from other departments/programs outlined in the Duke University Bulletin of Undergraduate Instruction (http://registrar.duke.edu/bulletins/undergraduate/). The additional requirements usually consist of 10 courses for a second major, 5 courses for a minor, and 6 courses for a certificate. Some of these courses can be double-counted towards both the BME degree and the second major, minor or certificate in the Trinity College. For example, two courses required for the second major in economics may be counted as two of the five SSH courses required for the BME degree. To reduce the work load for obtaining the second major, minor, or certificate in the Trinity College during the regular academic semesters, students can either take the required Trinity courses as unrestricted electives in the BME curriculum or take them in the summer. 4 + 1 BSE/MS Program (Five-Year Combined Bachelor/Master Degree Program)

The program offers a five-year combined Bachelor of Science and Master of Science degree in biomedical engineering. This is a great opportunity for students who want to broaden their undergraduate research experience or to obtain advanced training in biomedical engineering. In addition to the benefit of completing the dual degrees in five years, students pay only the undergraduate full time tuition for their graduate courses taken in the senior year. The degree requires that the students fulfill the standard degree requirements for Bachelor of Science plus an additional 30 units of upper level courses suitable for a graduate degree. (In the Graduate School, a 3-hour/week course is counted as 3 units.) Up to 15 graduate course units (5 graduate courses) out of the 30 units can be taken in the senior year, provided that these courses are not used to fulfill the Bachelor degree requirements and they are not Independent Study

courses. If you complete two or more courses toward your MS degree before completing your

senior year, you can easily complete the remaining graduate courses in one year beyond your

BSE. More information can be found here (http://www.pratt.duke.edu/4+1-bse-ms). To complete both Bachelors and Masters degrees in five years:

• Develop course plans for your senior year and for one graduate year with your academic adviser and obtain Director of Graduate Studies (DGS) approval

• Take the GRE exam in the Senior Fall • Apply for admission to Duke's Graduate School during senior fall. Apply online here

(http://gradschool.duke.edu/admissions/index.php). Advising

(a) Assignment of BME advisors: Due to the high student/faculty ratio in the BME program, the BME faculty do not advise freshmen. Students may declare their major by the end of freshmen year and after declaration a BME advisor will be assigned. The assignment of faculty advisors is

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based upon the major interests (e.g. BME/EE dual major) expressed by the students and the need to balance the number of advisees per faculty. Currently, each BME faculty member advises an average of twenty students.

Students can declare majors or change them at any time after freshmen year. To do this, the students need to complete an online form (http://www.pratt.duke.edu/forms/declaration-of-major).

(b) Freshman advising: In order to provide program information to freshmen interested in BME,

all students are invited to an orientation presented by the BME Director/Associate Director of

Undergraduate Studies (DUS) at the end of August, prior to the start of classes. The presentation

covers the degree requirements and commonly asked questions. Individual advising sessions can

be arranged if requested. In October and March/April, during the pre-registration periods, the

BME DUS and/or Associate DUS will also hold open consultation sessions for the first year

students who have BME-related questions.

To assist undecided students choosing a major in engineering, an elective course, EGR 10:

Introduction to Engineering, is offered to first year students in the fall term. This course surveys

the fields of engineering offered by the Pratt School of Engineering, including two presentations

from each department given by senior students, faculty, industrial leaders, and/or recent alumni.

(c) Pre-registration advising of BME students: Students meet with their advisers during the pre-

registration period in March/April for the fall semester and in October for the spring semester.

The advisor reviews the student's academic report, discusses with the student about the courses

that he or she will take in the following semester. The advisor maintains a record of the student’s

current academic plan. The student is responsible for informing the adviser of any changes in the

plan.

(d) Global Education advising: Students who participate in the Global Education program need

to develop an academic plan with their advisors several semesters in advance. This plan includes

the courses to be taken in foreign countries and the remaining courses to be taken after returning

to Duke. Students intending to study abroad should plan to travel in the fall semester of their

Junior year. In the semester prior to study abroad, students submit requests to the BME Associate DUS. The process for approval of courses in the study abroad program is the same as

that used for all transfer courses. For details, see http://studyabroad.duke.edu.

(e) Career advising: Students can discuss their career plans with their advisors. In addition,

advisors can help students to identify specific sequences of courses or dual major options that are

most appropriate for them. Information on Internship, Co-Op, Employment, and Graduate School Opportunities

Information on internship, co-op, and employment opportunities is posted on the website

of Duke University Career Center: http://www.studentaffairs.duke.edu/career. In addition to

maintaining the websites mentioned above, the Career Center organizes various career-related

activities. These include (a) career advice sessions, (b) industrial interview events, (c) graduate

school recruiting events, and (d) workshops and seminars on internship, co-op, and employment

that are specific for engineering or BME students. The workshops and seminars are announced

via emails and posted on the TV monitors in the engineering buildings. The Career Center is

located in Smith Warehouse at 114 S. Buchanan Blvd, Bay 5; and Teri Mill is the Career

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Advisor for Engineering, Technology and Physical Sciences. Her email address is

[email protected]. In addition to the Career Center, Russell Holloway

([email protected]), Associate Dean of Corporate and Industry Relations in the Pratt

School of Engineering, helps Pratt students to connect with corporations for internship

opportunities. For more information, see http://www.pratt.duke.edu/undergraduate-internship.

Sometimes, the information on internship, co-op, employment, and graduate school opportunities

is sent directly to BME faculty or department. When it happens, the information will be

distributed to BME students via emails or posted on the Bulletin board outside the BME

departmental office.

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Table 1a

BME Major (matriculating classes < 2008)

Freshman Year

Fall Semester Spring Semester

Chemistry 21L Principles of Chemistry I Chemistry 22L Principles of Chemistry II

EGR 53L Computational Methods in Engineering Physics 61L Introductory Technical Physics I 1

Math 31 Introductory Calculus I Math 32 Introductory Calculus II

Writing 20 Social Science or Humanities Elective

Sophomore Year


Physics 62L Introductory Technical Physics II 1 BME 153L Biomedical Electronics and Measurements I

5

Biology 25L Principles of Biology BME 100L Modeling Cellular and Molecular Systems

BME 110L Introductory Biomechanics or EGR 75L BME 83L Introduction to Biomaterials or ME 83L

Math 103 Intermediate Calculus 2 Math 107 Linear Algebra and Differential Equations

2

Social Science or Humanities Elective Social Science or Humanities Elective

Junior Year


BME 207 Transport Phenomena in Biological Systems BME 101L Electrobiology

BME 171 Signals and Systems or ECE 54L BME 154L Biomedical Electronics & Measurements II

Math 108 Ordinary and Partial Differential Equations 2 Stat 113 Probability and Statistics for Engineers

Life Science Elective Social Science or Humanities Elective

Senior Year


BME Design 3 BME Elective

4

BME Elective4

BME Elective4

BME Elective4

Social Science or Humanities Elective

Elective Elective

1. See also the Physics requirements for different classes on Page 6.

2. Students with BME/Math dual-major need to take Math 104/105/131/133 in placement of 103/107/108.

3. Selected from the following list:

BME 227L Design in Biotechnology

BME 236L Biophotonics Instrumentation

BME 260L Devices for People with Disabilities

BME 262L Design for The Developing World

BME 264L Medical Instrument Design

4. It is recommended that at least 2 of 4 BME Electives be at the 200 level.

5. ECE 27 and 51 may be used in lieu of BME 153.

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Table 1b

BME Major (matriculating classes < 2008)

Course plan for students considering medical school

Freshman Year






Sophomore Year


Physics 62L Introductory Technical Physics II 1 BME 153L Biomedical Electronics and Meas. I

5

BME 83L Introduction to Biomaterials or ME 83L Biology 25L Principles of Biology

Math 103 Intermediate Calculus 2 Math 107 Linear Algebra and Differential Equations

2


Chemistry 151L Chemistry 152L

Junior Year


BME 110L Introductory Biomechanics or EGR 75L BME 101L Electrobiology



BME 100L Modeling Cellular and Molecular Systems Social Science or Humanities Elective

Senior Year


BME Design3 BME Elective

4

BME Elective4

BME Elective4

BME Elective4


BME 207 Transport Phenomena in Biological Systems Life Science Elective



3. Selected from the following list

BME 227L Biotechnology and Biological Device Design





4. It is recommended that at least 2 of 4 BME Electives be at the 200 level.

5. ECE 27 and 51 may be used in lieu of BME 153.

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Table 2a

BME Major (matriculating classes 2008, 2009)

Freshman Year


Chemistry 21L or 31L Principles of Chemistry I Chemistry 22L or 32L or 151L Principles of Chemistry II




Sophomore Year



Biology 25L Principles of Biology BME 100L Modeling Cellular and Molecular Systems

EGR 75L or BME 110L Introductory Biomechanics ME 83L or BME 83L Introduction to Biomaterials

Math 103 Intermediate Calculus2 Math 107 Linear Algebra and Differential Equations

2


Junior Year


BME 171 Signals and Systems or ECE 54L BME Area Core Class I3

Math 108 Ordinary and Partial Differential Equations 2 BME Area Core Class II

3

Life Science Elective BME 154L Biomedical Electronics & Measurements II

Social Science or Humanities Elective Stat 113 Probability and Statistics for Engineers

Senior Year


BME Design 4 BME Area Elective

5

BME Area Elective5

BME General Elective6



Elective Elective




BME 201L Electrophysiology (EL)

BME 202L Fundamentals of Biomaterials and Biomechanics (BB)

BME 207 Transport Phenomena in Biological Systems (MC)

BME 233 Modern Diagnostic Imaging Systems (IM)







5. Both BME Area Electives (Table 9) must be from the same Area of Focus.

6. BME General Electives can be at any level.

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Table 2b

BME Major (for matriculating classes 2008, 2009)

Course plan for students considering medical school Freshman Year


Chemistry 21L or 31L Principles of Chemistry I Chemistry 22L or 32L Principles of Chemistry II




Sophomore Year



EGR 75L or BME 110L Introductory Biomechanics Biology 25L or Biology 101L


2


Chemistry 151L Organic Chemistry I Chemistry 152L Organic Chemistry II

Junior Year


ME 83L or BME 83L Introduction to Biomaterials BME Area Core Class I3

BME 100L Modeling Cellular and Molecular Systems BME Area Core Class II3



Senior Year



5

BME Area Elective5


Life Science Elective


















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Table 3a

BME Major (matriculating classes 2010)

Freshman Year


Chemistry 31L Principles of Chemistry I Chemistry 32L or 151L Principles of Chemistry II




Sophomore Year



Biology 101L Molecular Biology: Genes to Proteins BME 100L Modeling Cellular and Molecular Systems

EGR 75L Mechanics of Solids ME 83L Structure and Properties of Solids


2


Junior Year


BME 171 Signals and Systems or ECE 54L BME Area Core Class I3

Math 108 Ordinary and Partial Differential Equations 2 BME Area Core Class II

3


Social Science or Humanities Elective Stat 113 Probability and Statistics for Engineers

Senior Year



5

BME Area Elective5




Elective Elective
















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Table 3b

BME Major (for matriculating classes 2010)

Course plan for students considering medical school Freshman Year


Chemistry 21L or 31L Principles of Chemistry I Chemistry 22L or 32L Principles of Chemistry II




Sophomore Year



EGR 75L Mechanics of Solids Biology 101L Molecular Biology: Genes to Proteins


2


Chemistry 151L Organic Chemistry I Chemistry 152L Organic Chemistry II

Junior Year


ME 83L Structure and Properties of Solids BME Area Core Class I3 (BME 201L)

BME 100L Modeling Cellular and Molecular Systems BME Area Core Class II3



Senior Year



5

BME Area Elective5


Life Science Elective


















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Table 4a

BME/ECE Dual Major (matriculating classes of 2006, 2007)

Freshman Year

Fall Semester Spring Semester Writing 20/ Social Science or Humanities Elective Social Science or Humanities Elective /Writing 20 Chemistry 21L Principles of Chemistry I Chemistry 22L Principles of Chemistry II

Math 31 Introductory Calculus I Math 32 Calculus II

EGR 53L Computer Methods in Engineering Physics 61L Mechanics

Sophomore Year

Fall Semester Spring Semester Physics 62L Electricity, Magnetism, and Optics ECE 51L Microelectronic Devices & Circuits Compsci 100E Program Design and Analysis ECE 54L Linear Systems ECE 27L Fundamentals of ECE Math 107 Linear Algebra and Differential Equations Math 103 Intermediate Calculus EGR 75L Mechanics of Solids Social Science or Humanities Elective Social Science or Humanities Elective Junior Year


ME 83 Structure and Properties of Solids ECE Concentration Elective 11

ECE 52L Switching Theory & Logic Design BME 154L Medical Instrumentation Math 108 Ordinary and Partial Diff. Equations Stat 113 Probability and Statistics Biology 25L Principles of Biology BME 100L Modeling Cellular and Molecular Systems ECE 53L Electromagnetic Fields Social Science or Humanities Elective Senior Year


ECE Concentration Elective 21 ECE Concentration Elective 3

1 BME 236 or 264/BME Elective

2 BME Elective2/BME 236 or 264

Social Science or Humanities Elective BME Elective2

BME 101L Electrobiology Life Science Elective3

1. At least two ECE Concentration Electives must be from the same Concentration Area.

2. At least one BME Elective must be at the 200 level.

3. From approved list of Life Science Electives (Table 7).

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Table 4b

BME/ECE Dual Major (matriculating classes 2008)

Freshman Year

Fall Semester Spring Semester Writing 20/ Social Science or Humanities Elective 1 Social Science or Humanities Elective 1/Writing 20 Chemistry 21L or 31L Principles of Chemistry I Chemistry 22L or 31L or 151L Principles of Chem. II Math 31L Introductory Calculus I Math 32 Calculus II EGR 53L Computer Methods in Engineering Physics 61L Mechanics Sophomore Year

Fall Semester Spring Semester Physics 62L Electricity, Magnetism, and Optics ECE 51L Microelectronic Devices & Circuits Compsci 100E Program Design and Analysis ECE 54L Linear Systems ECE 27L Fundamentals of ECE Math 107 Linear Algebra and Differential Equations Math 103

3 Intermediate Calculus EGR 75L Mechanics of Solids

Biology 25L or Biology 101L BME 100L Modeling Cellular and Molecular Systems Junior Year


ME 83 Structure and Properties of Solids ECE Concentration Elective 11

ECE 52L Switching Theory & Logic Design BME 154L Medical Instrumentation Math 108 Ordinary and Partial Diff. Equations Stat 113 Probability and Statistics ECE 53L Electromagnetic Fields BME 201L Electrobiology or

BME 233 Modern Diagnostic Imaging Systems2

Social Science or Humanities Elective 2 Social Science or Humanities Elective 3 Senior Year


ECE Concentration Elective 21 ECE Elective

BME 236 or 264/BME General Elective BME General Elective/BME 236 or 264 BME Area Elective

2 Social Science or Humanities Elective 5

Science or Humanities Elective 4 Physiology or Life Science Elective3

1. At least two ECE Concentration Electives must be from the same Concentration Area

2. If BME 201L is taken the Area Elective must be from the Bioelectricity Area

If BME 233 is taken the Area Elective must be from the Imaging and Sensors Area

3. If BME 233 is taken, choose from approved list of Physiology Electives (Table 7a) If BME 201L is take, choose from the approved list of Life Science Electives (Table 7)

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Table 5a

BME/ME Dual Major (for matriculating class of 2007)

Freshman Year





Writing 20 Academic Writing EGR 20 Engineering Innovation

Sophomore Year



Math 103 Intermediate Calculus Math 107 Linear Algebra and Differential Equations

EGR 75 Mechanics of Solids EGR 123L Dynamics

Bio 25L Principles of Biology BME 100L Modeling Cellular and Molecular Systems

Social Science or Humanities Elective ME 83 Structure and Properties of Solids

Junior Year


ME 131 Mechanical Engineering Analysis for Design BME 154L Biomedical Electronics & Measurements II

Math 108 Ordinary and Partial Differential Equations ME 101 Thermodynamics

BME 171 Signals and Systems or ECE 54L ME 126L Fluid Mechanics

Stat 113 Probability and Statistics Life Science Elective 3


Senior Year


ME 125L Measurement & Modeling Dynamic Systems BME 260/ME 160L Design2

ME 141L Mechanical Design Biomechanics Elective4

ME 150L Heat and Mass Transfer BME Elective


1. See the Physics requirements on Page 6.

2. BME 260L or ME 160 with BME project.

3. Selected from Table 7.

4. Selected from the approved biomechanics electives listed in Table 8.

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Table 5b

BME/ME Dual Major (for matriculating classes 2008)

Freshman Year Fall Semester Spring Semester Chemistry 21L or 31L Principles of Chemistry I Chemistry 22L or 32L or 151L Principles of Chemistry II EGR 53L Computational Methods in Engineering Physics 61L Introductory Technical Physics I

1 Math 31 Introductory Calculus I Math 32 Introductory Calculus II Writing 20 Academic Writing EGR 20 Engineering Innovation Sophomore Year Fall Semester Spring Semester Physics 62L Introductory Technical Physics II

1 BME 153L Biomedical Electronics and Measurements I Math 103 Intermediate Calculus Math 107 Linear Algebra and Differential Equations

EGR 75 Mechanics of Solids EGR 123L Dynamics Biology 25L or Biology 101L BME 100L Modeling Cellular and Molecular Systems Social Science or Humanities Elective ME 83 Structure and Properties of Solids Junior Year Fall Semester Spring Semester ME 101 Thermodynamics BME 154L Biomedical Electronics & Measurements II

ME 131 Analysis for Design BME 202 Biomechanics/Biomaterials

Math 108 Ordinary and Partial Differential Equations ME 126L Fluid Mechanics BME 171 Signals and Systems or ECE 54L Physiology Elective

3 Stat 113 Probability and Statistics Social Science or Humanities Elective Senior Year Fall Semester Spring Semester ME 125L Measurement & Modeling Dynamic Systems BME 260/ME 160L Design

2

ME 141L Mechanical Design Biomat/Biomech Area Elective4

ME 150L Heat and Mass Transfer Social Science or Humanities Elective


Students with AP credits should pay particular attention to prerequisites when rearranging the schedule.

1. See the Physics requirements on Page 6.

2. BME 260L or ME 160 with BME project.

3. Selected from approved list of Physiology Electives (Table 7a).

4. Selected from Table 8.

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Table 6a

BME/CEE Dual Major (for matriculating classes < 2008)

Freshman Year






Sophomore Year



ME 83L or BME 83L Introduction to Biomaterials EGR 123L Dynamics

BME 110L Introductory Biomechanics or EGR 75L Biology 25L or Biology 101L

Math 103 Intermediate Calculus Math 107 Linear Algebra and Differential Equations


Junior Year


BME 171 Signals and Systems or ECE 54 L BME 101L Electrobiology

CE 120L Chemistry and Microbiology for

Environmental Engineers

CE 123L Water Resources Engineering

CE 122L Fluid Mechanics CE 130L Structural Design and Optimization

Math 108 Ordinary and Partial Differential Equations Stat 113 Probability and Statistics for Engineers


Senior Year


CE Elective2 BME/CEE Design

3

CE 124L Environmental Engineering BME Elective4

EGR 115 Systems Optimization Social Science or Humanities Elective

Social Science or Humanities Elective BME 100L Modeling Cellular and Molecular Systems


2. Selected from the following list of CE electives:

CE 239. Environmental Molecular Biotechnology

CE 240. Chemical Fate of Organic Compounds

CE 241. Physical and Chemical Treatment Processes in Environmental Engineering

CE 242. Environmental Aquatic Chemistry

CE 243. Physiochemical Unit Operations in Water Treatment

CE 244. Biological Processes in Environmental Engineering

CE 245. Pollutant Transport Systems

CE 246. Water Supply Engineering Design

CE 247. Air Pollution Control Engineering

CE 248. Solid Waste Engineering

CE 249. Control of Hazardous and Toxic Waste


CE 193 Integrated Environmental Design

BME 227 Design in Biotechnology

BME 262 Design for the Developing World

4. It must be a 200 level BME elective or BME 191, Independent Study.

Version F10 24

Table 6b

BME/CEE Dual Major (for matriculating classes 2008)

Freshman Year

Fall Semester Spring Semester Chemistry 21L or 31L Principles of Chemistry I Chemistry 22L or 32L or 151L Principles of Chemistry II EGR 53L Computational Methods in Engineering Physics 61L Introductory Technical Physics I

1 Math 31L Introductory Calculus I Math 32L Introductory Calculus II Writing 20 Social Science or Humanities Elective Sophomore Year

Fall Semester Spring Semester Physics 62L Introductory Technical Physics II

1 BME 153L Biomedical Electronics and Measurements I

Biology 25L or Biology 101L EGR 123L Dynamics EGR 75L Mechanics of Solids ME 83L Structure and Properties of Solids Math 103 Intermediate Calculus Math 107 Linear Algebra and Differential Equations Social Science or Humanities Elective Social Science or Humanities Elective Junior Year

Fall Semester Spring Semester BME 171 Signals and Systems or ECE 54L BME 202L Biomechanics/Biomaterials or

BME 207 Transport Phenomena in Biological Systems4

CE 120L Chemistry and Microbiology for

Environmental Engineers CE 123L Water Resources Engineering

CE 122L Fluid Mechanics CE 130L Structural Design and Optimization Math 108 Ordinary and Partial Differential Equations Stat 113 Probability and Statistics for Engineers BME 100L Modeling Cellular and Molecular Systems BME 154L Biomedical Electronics & Measurements II Senior Year

Fall Semester Spring Semester CE Elective

2 BME/CEE Design 3

CE 124L Environmental Engineering BME Area Elective 4

EGR 115 Systems Optimization Social Science or Humanities Elective Social Science or Humanities Elective Life Science or Physiology Elective

5


2. Selected from the following list of CE electives:

CE 239. Environmental Molecular Biotechnology

CE 240. Chemical Fate of Organic Compounds

CE 241. Physical and Chemical Treatment Processes in Environmental Engineering

CE 242. Environmental Aquatic Chemistry

CE 243. Physiochemical Unit Operations in Water Treatment

CE 244. Biological Processes in Environmental Engineering

CE 245. Pollutant Transport Systems

CE 246. Water Supply Engineering Design

CE 247. Air Pollution Control Engineering

CE 248. Solid Waste Engineering

CE 249. Control of Hazardous and Toxic Waste


CE 193 Integrated Environmental Design

BME 227 Design in Biotechnology

BME 262 Design for the Developing World

4. If BME 202L is taken, the Area Elective must come from the Biomaterials/Biomechanics Area If BME 207 is taken, the Area Elective must come from the Molecular, Cellular and Tissue Engineering Area

5. If BME 202L is taken, choose from the approved list of Physiology Electives (Table 7a) If BME 207 is taken, choose from the approved list of Life Science Electives (Table 7)

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Table 7. Approved BME Life Science Elective Courses

BME students are required to take Biology 25L (or receive the AP credit for Biology 19) or

Biology 101L and another life science course from the following list. Other courses can be taken upon

approval of the BME DUS.

Biochemistry

Bch 227 Introductory Biochemistry I: Intermediary Metabolism

Bch 228 Introductory Biochemistry II

Evolutionary Anthropology

Evanth 133L The Human Body

Evanth 135 Human Functional Anatomy

Evanth 151 Anatomy of the Lower Extremities

Evanth 172L Primate Anatomy

Biology

Bio 102L Gateway to Biology: Genetics and Evolution

Bio 103L General Microbiology

Bio 105 Introduction to Mathematical Biology

Bio 108L Developmental and Comparative Anatomy of Vertebrates

Bio 117 Cell and Organsimal Physiology

Bio 118 Principles of Genetics and Cell Biology I

Bio 119 Principles of Genetics and Cell Biology II

Bio 120 Principles of Evolution

Bio 122 Population Genetics

Bio 124 Molecular Evolution

Bio 149 Comparative Biomechanics

Bio 150L Physiology of Marine Animals

Bio 151L Principles of Animal Physiology

Bio 154 Fundamentals Neuroscience

Bio 155L Biochemistry of Marine Animals

Bio 158L Introduction to Modern Microscopy

Bio 164D Developmental Biology

Bio 176AL Marine Invertebrate Zoology

Bio 184L Experimental Cell and Molecular Biology

Bio 185L Experiments in Development and Molecular Genetics

Bio 187 Evolutionary Genetics

Bio 214 Biophysics in Cell and Developmental Biology

Bio 220L Mycology

Bio 244 Principles of Immunology (C-L: Immunology 244)

Bio 269 Advanced Cell Biology

Bio 283 Molecular Genetics of Organelles

Bio 284 Molecular Population Genetics

Bio 288 Mathematical Population Genetics

Bio 291 Mathematical Biology

Chemistry

Chem 176 Biophysical Chemistry

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Pharmacology

Pharm 150 Drug Actions and Reactions

Pharm 160 Drugs, Brain, and Behavior

Pharm 233 Essentials of Pharmacology and Toxicology

Pharm 254 Mammalian Toxicology

Medical Physics

MP 205 Anatomy and physiology for medical physicists

Computer Sciences

COMPSCI 160 Introduction to Computational Genomics

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Table 7a. Approved BME Physiology Courses

BME students are required to take Biology 25L (or receive the AP credit for Biology 19) or

Biology 101L and another life science or physiology course. This is the approved list of Physiology

Classes. Other courses can be taken upon approval of the BME DUS.

Evolutionary Anthropology

Evanth 133L The Human Body

Evanth 151 Anatomy of the Lower Extremities

Evanth 172L Primate Anatomy

Biology

Bio 103L General Microbiology

Bio 108L Developmental and Comparative Anatomy of Vertebrates

Bio 117 Cell and Organsimal Physiology

Bio 149 Comparative Biomechanics

Bio 150L Physiology of Marine Animals

Bio 151L Principles of Animal Physiology

Bio 154 Fundamentals Neuroscience

Bio 184L Experimental Cell and Molecular Biology

Bio 214 Biophysics in Cell and Developmental Biology

Bio 269 Advanced Cell Biology

Medical Physics

MP 205 Anatomy and physiology for medical physicists

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Table 8. Approved Biomechanics elective courses

BME 230 Tissue Biomechanics.

BME 231 Intermediate Biomechanics.

BME 239 Cell Transport Mechanisms.

BME 265 Cell biomechanics (Note: the course number is temporary. It will soon be replaced by a

permanent number.)

BME 265 Biofluid mechanics (Note: the course number is temporary. It will soon be replaced by a

permanent number.)

CEE 201 Continuum Mechanics

CEE 251 Engineering Analysis and Computational Mechanics

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Table 9. BME Area Electives Currently Offered

(BB) Biomechanics and Biomaterials (EL) Bioelectricity BME 207 – Transport Phenomena in Biological Systems BME 204 – Measure. and Control of Cardiac Electrical Events

BME 208 – Theoretical and Applied Polymer Science BME 210 – Molecular Basis of Membrane Transport BME 215 – Biomedical Materials and Artificial Organs BME 211 – Theoretical Electrophysiology BME 217 – Cell Mechanics and Mechanotransduction BME 212 – Theoretical Electrocardiography BME 218 – Biotechnology and Bioprocess Engineering BME 213L – Nonlinear Dynamics in Electrophysiology

BME 220L – Introduction to Biomolecular Engineering BME 235 – Acoustics and Hearing BME 227L – Design in Biotechnology BME 252 – Neural Signal Acquisition BME 230 – Tissue Biomechanics BME 253 – Computational Neuroengineering BME 231 – Intermediate Biomechanics BME 256 – Neural Prosthetic Systems

BME 242L – Intro. to Bionanotechnology Engineering BME 247 – Drug Delivery

BME 260L – Devices for People with Disabilities BME 275 – Intro to Biofluid Mechanics

(IM) Imaging and Measurement Systems (MC) Molecular, Cellular and Tissue Engineering BME 155 – Safety of Medical Devices BME 210 – Molecular Basis of Membrane Transport

BME 204 – Measure. and Control of Cardiac Electr. Events BME 216 – Transport Phenomena in Cells and Organs

BME 222 – Principles of Ultrasound Imaging BME 217 – Cell Mechanics and Mechanotransduction

BME 234 – Modern Microscopy BME 218 – Biotechnology and Bioprocess Engineering BME 235 – Acoustics and Hearing BME 220L – Introduction to Biomolecular Engineering

BME 236L – Biophotonic Instrumentation BME 221 – Modeling and Engineering Gene Circuits

BME 237 –Biosensors BME 237 – Biosensors BME 238 – Advanced Optics BME 239 – Cell Transport Mechanisms BME 256 – Neural Prosthetic Systems BME 240L – Environmental Molecular Biotechnology BME 242L – Intro. to Bionanotechnology Engineering

BME 247 – Drug Delivery BME 248 – Tissue Engineering BME 258L – Genome Science & Technology Lab

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Additional Information on Courses:

• All required BME courses, except a few BME design courses, are usually offered in both semesters.

• The following BME courses are prerequisites for other BME courses:

ME 83/BME 83 for BME 202, BME 215, BME 218, BME 237, BME 242L

BME 100 for BME 207, BME 215, BME 237, BME 242L

BME 101 for BME 204, BME 211, BME 212, BME 213

EGR 75/BME 110 for ME 83, BME 230, BME 231

BME 153 for BME 101, BME 154

BME 154 for BME 236, BME 260,BME 262, BME 264

BME 171 for BME 154, BME 233

BME 207 for BME 216, BME 227, BME 247

Note: (i) There are two prerequisites for BME 171. One is Math 107; the other is one of the following:

BME 153, or (ECE 27L and ECE 51L).

• Equivalent courses

ME 83 = BME 83 (note that ME 83 has EGR 75 as a prerequisite)

EGR 75 = BME 110

ECE 54 = BME 171 (Not for BME/ECE dual majors, BME/ECE duals must take ECE 54L)

Documents

BME-Undergrad Advising Handbook