BioMatters - Spring 2009

BioMattersA MichBio Publication Showcasing Michigan’s Biosciences Industry

Michigan Incubators Boost State’s Bioscience Entrepreneurs

S P R I N G 2 0 0 9

Also Featured:

Michigan Universities Pack a Powerful R&D Punch

Governments Building Foundations for Regional Bioscience Growth

In This Issue:

2009 Michigan Biosciences Directory and Resource Guide

INNovatIoN, techNoloGy aNd coMMeRcIalIzatIoN

IN MICHIGAN, SOMETHING NEW IN HIGH-TECH INNOVATION IS HAPPENING EVERY DAY.

Working with our partners at MichBio, the Michigan Economic Development CorporationSM can connect high-tech companies and entrepreneurs to services, incentives, networking opportunities and venture capital through resources like the 21st Century Jobs Fund to help them grow and prosper.

Visit MichiganAdvantage.org and learn how Michigan can give your biotech company the Upper Hand.

MichiganAdvantage.org

1 BioMatters | Spring 2009

Dear Innovator,

Whether you are looking to launch a new company, expand, or relocate operations, I encourage you to consider the

advantages Michigan has to offer. With an abundance of high-tech talent, a legacy of technical know-how, proximity to 21st

century infrastructure, and strong state and local support, Michigan is the perfect place to take your life science enterprise

to the next level.

ThebiosciencesectorisapillarofMichigan’seconomicdiversificationstrategy.Together,ourpublicandprivateinvest-

ments in life science research and development and our strong partnerships with educational institutions, entrepreneurs,

and commercial businesses position Michigan well as a world-class center of life science research and product development.

Over the past decade, Michigan has earned a well-deserved reputation for leadership in bioscience innovation. We have

made investments totaling more than a half billion dollars to support initiatives such as the Life Science and Technology

tricorridors, the 21st Century Jobs Fund, the Venture Michigan Fund, and the Bioscience Research and Commercialization

Center. And we are the #2 state in the nation for overall industrial research and one of the fastest growing life science

states with more than 125 new companies since 2000 and more than 540 life sciences companies overall.

Our aggressive strategy to grow and diversify Michigan’s economy, along with commercialization activities, healthy

sources of venture capital, and other growth opportunities created by our targeted initiatives, assure that Michigan will

continue to be an important life sciences center well into the future.

Sincerely,

Jennifer Granholm

Governor of Michigan

G O V E R N O R ’ S M E S S A G E

Wherever you are in the world, wherever you are in the R&D process, Michigan bioscience companies and organizations have the expertise, technologies and development understanding to give you the “Upper Hand” advantage.

Join us in the Michigan Pavilion #3147

HOSTED By:

WITH MICHIGAN ExHIBITORS:

Ann Arbor SPARK • Ash Stevens Beaumont BioBank • Genetics Squared LLCJasper Clinical R&D • Kalexsyn, Inc.MSU Technologies • Oakland County’s Medical Main St.Southwest Michigan First • The Right PlaceTSRL, Inc. • University of Michigan Technology Transfer Van Andel Institute • Velesco Pharmaceutical ServicesWayne County • Wayne State University • zuSyn, Inc.

yOUR COMPLETE BIOSCIENCES PACKAGETHAT’S THE MICHIGAN “UPPER HAND” ADVANTAGE

2BioMatters | Spring 2009

Nurturing an idea into a marketable product and growing it into a dynamic, self-sustaining bioscience company is a process. How do Michigan companies connect with the right people, learn what they need to know, find the resources to keep the pipeline flowing?

We know people.

In a state boasting the world’s longest freshwater coastline, with oceans of lakes, where water is a way of life and life is good; in an industry that studies life at its core, MichBio is there to propel Michigan’s bioscience people, products and prospects.

Join us.

MichBio brings the total continuum together. We know the players, the market; and what it takes to succeed. We give you access to a valuable network of people representing all facets of the biosciences community. We are your matchmaker, your guru and your standard bearer.

Ann Arbor, MichigAn 734.527.9150 www.Michbio.org


Welcome to Michigan’s Biosciences Community! In this its second issue, BioMatters continues an up-front, inside look at

Michigan’s biosciences community today and the many exciting discoveries that

may lie ahead for tomorrow.

The biosciences are “big” business in the state and account for almost 96,000

direct and indirect jobs. Private bioscience R&D and academic research in Michigan

contributes $9.34 billion to the state’s GRP, including $2.5 billion in direct private

payroll. Michigan has an enviable bioscience infrastructure with an advantageous

business environment, strong commercialization resources and incentive programs,

an expert talent pool, and an exceptional quality of life.

The state is home to a myriad of bioscience companies involved in R&D,

manufacturing, and contract research/support services — “a complete package

for R&D”. Michigan has it all — from drugs and therapeutics, medical devices and

equipment, diagnostics and research tools, information technology systems and

software, clinical research and medical testing, as well as industrial biotechnology,

bio-agriculture, bio-defense, and bio-environmental. We are proud of our accomplish-

ments and growth, and are working hard to nurture today’s and tomorrow’s ventures,

and eager to give your business the “Upper Hand” Advantage.

The Michigan Biosciences Industry Association or MichBio, is a statewide,

non-profittradegroupdevotedtopromotingthegrowthofthebioscienceindustry

in Michigan. Our goal is to network the academic, industry and government par-

ticipants into a cohesive whole and to provide various resources, matchmaking to

serviceproviders,andpurchasingprogramstosupportcompaniesandaffiliatesinour

biosciences industry. We provide a forum for members to get to know each other and

connect the many bioscience companies operating today in Michigan. We coordinate

information among the many agencies and organizations interested in the biosciences

sector. MichBio also represents the interests of the bioscience industry in Michigan

before federal, state and local legislators and regulators. For whatever your needs

in the biosciences — we’re here to help you get started, grow and succeed.

MichBio looks forward to meeting you at BIO 2009. Come see what Michigan’s

biosciences are all about — visit with us at the Michigan Pavilion (Booth #3147).

Stephen Rapundalo, Ph.D.

President and CEO, MichBio

P R E S I D E N T ’ S M E S S A G E

P R O F E S S I O N A L S TA F F

C O N TA C T I N F O R M AT I O N

Stephen T. Rapundalo

President and CEO

[email protected]

734.527.9144

Stephen Field

Director,

Operations and Controller

[email protected]

734.527.9145

Jayne Berkaw

Director,

Marketing and Communications

[email protected]

734.527.9147

Heather Kusiak

Administrative Specialist

[email protected]

734.527.9150

Physical Address

3520 Green Court, Suite 450

Ann Arbor, Michigan 48105-1579

Mailing Address

P.O. Box 130199

Ann Arbor, Michigan 48113-0199

Phone

734.527.9150

Fax

734.302.4933

Website

www.michbio.org

General Information

[email protected]

BioMatters Next Issue: FALL 2009FEATURINGl Informatics: Where Technology Meets the Challenges of Sciencel Michigan Leading in High-Growth Generics Industryl And more stories chronicaling news, trends and issues affecting Michigan’s biosciences industry


CORPORATE SPONSORS

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SUPPORTERBiotechnology Business

Consultants, Caraco,sanofi-aventis U.S.,

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M E D I A

ExECUTIVE OFFICERS Chairman Michael Kurek, Ph.D.Biotechnology Business ConsultantsPartner/President

Vice ChairmanStephen Munk, Ph.D.Ash Stevens, President and CEO

President and CEOStephen T. Rapundalo, Ph.D.MichBio, President and CEO

Secretary Christina DeHayesAsterand, Inc., General Counsel

Treasurer Matthew L. McCollErnst & Young LLP, Partner

Assistant TreasurerRyan Noel Division of Metabolism, Endocrinology and Diabetes, University of Michigan, Administrator

DIRECTORSDan CalvoAssay Designs, Inc., President and CEO

Linda Chamberlain, Ph.D.West Michigan Science andTechnology InitiativeExecutive Director

David Felten, M.D., Ph.D.Beaumont Hospitals, Research InstituteVice President, Research and Medical Director

J. Patrick ElliotTerumo Cardiovascular Systems Corp.Vice President, Business Development

James Freeman, Ph.D.Pfizer Animal HealthVice President, Laboratory Sciences

Ricardo (Richard) Fuentes Jr.Dow Corporate Venture CapitalGlobal Life Science Investment Director

Teri GriebU of M Medical School, Office of ResearchDirector of Administration for ResearchOffice of Research and Graduate Studies

Mark KielbAltarum InstituteChief Financial Officer

Barry KlineGlaxoSmithKlineDirector, Market Development

Michael Kurek, Ph.D.Biotechnology Business ConsultantsPartner/President

Paul MorrisConsultant

Stephen Munk, Ph.D.Ash Stevens, President and CEO

Stephen T. Rapundalo, Ph.D.MichBio, President and CEO

John J.H. Schwarz, M.D.Family Health CenterPhysician,Former U.S. Representative

Eric StiefWayne State University — Technology CommercializationLicensing Manager Director of Venture Development

Karen Studer-RabelerCoy Manufacturing/Coy Laboratory ProductsGeneral ManagerVice President, Business Development

David ZimmermannKalexsyn, Inc.Chief Executive Officer

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BioMattersT A B L E O F C O N T E N T S

A D V E R T I S E R SAnn Arbor Region CRO Network ........................9 Ash Stevens ....................................................... 43Asterand ............................................................ 42Bank of Ann Arbor ............................................ 17Beaumont Hospitals .......................................... 37Biotechnology Industry Organization (BIO) ........ 28The Brooks Industrial & Research Park ............ 18Business Review ................................................ 33CMU Research Corporation .............................. 46Cutting Edge Histology ..................................... 23DBA Analytical .................................................. 17Doeren Mayhew ................................................ 36Dykema ...............................................................6Great Lakes Entrepreneur’s Quest ..................... 40Hylant Group ..................................................... 18Karmanos Institute ........................................... 46Lake Superior State University .......................... 43

ProPharma Group ............................................. 43Quest Research Institute ................................... 22Rader, Fishman & Grauer PLLC ........................ 46RS Electronics ................................................... 23Smith Haughey Rice & Roegge .......................... 26Steve Raphael .................................................... 47Switchback ........................................................ 10TransPharm Preclinical Solutions ..................... 23Twin Bay Medical .............................................. 47University of MichiganTech Transfer ................ 29University of Michigan Department of Biomedical Engineering .......................... 26Varnum Riddering Schmidt Howlett ................ 17Warner Norcross and Judd ................................ 37Wayne County ................................................... 48Wayne State University ...................................... 23West Michigan Science & Technology Initiative ....40

Lumigen ............................................................ 26MichBio ...............................................................2Michigan Economic Development Corporation ................................................ IFCMichigan Small Business Technology Development Center ..................................... 42Midwest Cleanroom Associates ........................ 46MPI Research .................................................... 14Oakland County Planning and Economic Development .............................................OBCOakland University .............................................5P&M Corporate Finance, LLC .........................IBCPfizer ................................................................. 11Pharmacision .................................................... 18PhRMA .............................................................. 29Pinnacle Insurance ............................................ 42Prima Communications .................................... 47

4 MichBio Corporate Sponsors, Officers, Directors and Committees

15 Southwest Michigan Innovation Center a Leader

12 Feature StOry:Michigan Incubators Hatch Bioscience Innovators

27Students Collaborate to Give the Gift of Life

24

41

Michigan Proposal 2 Passage resurrects embryonic Stem Cell research in the State

Scientist Finds Insecticide Weapon Inside Spider Mouths

21Williamston Inventor takes aim at airway Obstructions

30 eCONOMIC DeVeLOPMeNt: Governments Building Foundations for regional Bioscience Growth

Feature stories and sidebars by Steve Raphael.

The following MichBio members are featured in this issue of BioMatters:Accuri Cytometers, Ann Arbor SPARK, Asterand, Inc., Beaumont Hospitals, Center for Applied Research & Technology, Central Michigan University Research Corporation

Delphi Medical Systems, Dow Pharma, Esperion Therapeutics, Inc., Henry Ford Health System, Honigman Miller Schwartz and Cohn LLP, Housey Pharmaceutical Research Laboratories, LLC, Johnson & Johnson Co., Kalexsyn, Inc., Kellogg Co., Michigan Economic Development Corporation, Michigan State University, NanoBio Corp., NanoMed Pharmaceuticals, Inc., Oakland County

Planning and Economic Development, Oakland University, Pfizer, PharmOptima, LLC, Proteos, Inc., Southwest Michigan First, Southwest Michigan Innovation Center, TechTown, Tech Initiatives Inc., The Right Place, Inc., University of Michigan Life Science Institute, Venomix, Inc., Wayne State University, West Michigan Science & Technology Initiative

Subscribe to BioMatters:Visit www.michbio.org and click “Subscribe” or call 734.527.9150.

19reSearCH: Michigan universitiesPack a Powerful r&D Punch

34 Open Source approach Opens Markets for ann arbor SParK

35MeDC Shepherds State’s Biosciences

49 GueSt OPINION: Balancing Life Science efforts For Sustainable rOI

44 NeW FrONtIerS: Pint-Sized Nano- medicine Industry

38teCHNOLOGy: State expects to be Sitting on top

50DIreCtOry & reSOurCe GuIDe


That was the conclusion

of a recent study released by

industry advocate, the Phar-

maceutical Research and Manu-

facturers of America (PhRMA),

which concluded that “Michigan

has the assets to support and

grow bioscience, particularly in

the presence of its major research universities.”

The study points out that university biosciences

expenditurestotaled$897millioninfiscal2007

with industry payrolls reaching nearly $2.5 billion

for the same period.

Michigan is home to more than 540 biosciences

enterprises from pharmaceutical and medical

device companies to diagnostics, bio-agriculture

and nutriceuticals. The state’s contract research

industry alone has the depth to handle business

from across the globe at any stage of development.

Michigan’s SmartZones™ fuel a robust pipeline

of Michigan biosciences companies. SmartZones™

are distinct geographical areas where technology-

based businesses gain from collaborations between

local universities, industry, research organiza-

tions, government agencies and other community

resources. The business incubators (see Feature

story p. 12) located within many SmartZones™

nurture entrepreneurism with wet lab services,

SBIR and STTR assistance and access to business

planning and funding sources. From the tip of the

Upper Peninsula to the bustling Lower Peninsula,

Michigan’s “Upper Hand” Advantage is its Complete

Biosciences Package. Look no further.

The study points out that

bioscience expenditures totaled 897 million with industry payrolls reaching nearly $2.5 billion.

Bioscience is “Big Business” in Michigan

These days, access to viable, high quality CROs can mean the difference between success and failure in rapidly moving a pharmaceutical to market. That’s why so many life science leaders are looking to Southeastern Michigan as a source for CRO support in every phase of product development. Here, in the heart of Michigan’s Life Science Research Corridor, they’re finding a unique concentration of expertise and resources spanning the entire product development continuum.

Introducing the Ann Arbor Region CRO Network In this dynamic quadrant of the Great Lakes State you will find dozens of high-capability CROs specializing in pharmaceutical product development. The Ann Arbor region CROs have formed an alliance network with the following capabilities:

n Experienced life science researchers and consultants

n A full spectrum of CROs, many of them headed by former scientists and executives from Pfizer, Warner-Lambert, Upjohn, and other life science research giants

n Accessible, affordable pharmaceutical product development

n Demonstrated success with a diverse client-base from start-up to established companies in the US, Europe, Asia & Australia

Why Michigan should be your source for life science product development

n #2 state overall for R&D expenditures

n #3-ranked university for R&D funding

n Rated the 2nd most business-friendly state

n 4th largest high-tech workplace in the nation

n One of the fastest-growing life science states

n More than $2 billion invested annually in life science research

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NextGen Science www.nextgensciences.com

TSRL, Inc. www.tsrlinc.com

Velesco pharmaceuticals Services www.velescopharma.com

FINANCIAL MATTERS FEATURE STORy

Michigan Incubators

Hatch Bioscience Innovators



Services include financial planning,

business consulting, laboratory and office

space and access to capital. It’s a good

approach because most of the promising

innovations are created by scientists and

entrepreneurs lacking two prime ingredi-

ents for success: business savvy and money.

“Most inventors do not know how to

formulate a business plan, business model,

etc.,” says Ken Van Der Wende, president and

CEO of the Center for Applied Research &

Technology (CART), which is located within

Central Michigan University’s Research

Corporation in Mt. Pleasant. “Almost all

startups have a hard time thinking through

and writing a good business plan. Virtually

all have a particular challenge with the pro

forma financials. All have funding challenges.”

CART And Mid-MiChigAn PUll THEIR WEIGHT Dendritic Nanotechnologies Inc. (DNT)

in Mt. Pleasant, a company with origins

dating back to The Dow Chemical Co., is

a huge CART success story. CART helped

DNT secure funding, develop its intellectual

property and catch the eye of Starpharma

Holdings Ltd., a Melbourne, Australia com-

pany developing nanotechnology products

for the pharmaceutical industry that acquired

DNT in 2006.

Among other CART successes is Bauer

BioMedical whose genetic diagnostics tech-

From mid-town Detroit to downtown Grand Rapids and up north to the great outdoors of Houghton in the Upper Peninsula, innovation is emerging from Michigan business incubators. Incubatorsbringtogethertheknowledgeandresourcesoflocalgovernments,nonprofits,industryand

academiatopropelMichigan’seconomyintothe21stCentury.Theyprovideawiderangeofscientific

and business support services to help scientists and entrepreneurs translate their innovations and

technologies into commercial products.

nologies make possible the precise detection

of cancers and other disease conditions

through the analysis of peripheral blood

or body fluid specimens, all without the

need for invasive biopsy or excision of the

diseased tissues.

CART partners with other economic

development organizations throughout

the region, including Saginaw Valley State

University and the MidMichigan Innovation

Center. Together these organizations are

developing a regional business incubator

network to improve their collective efficiency

and effectiveness.

Just to the east in Midland, the four-

year-old MidMichigan Innovation Center

(MMIC) is making its presence felt too. Like

the other incubators across the state MMIC

provides a wealth of critical resources,

valuable services, flexible facilities, and

entrepreneurial training and education to

help support business ventures.

Our “role is to not only help our tenants

and virtual tenants by connecting them to

resources they wouldn’t otherwise be aware

of, but to inform and educate entrepreneurs

in our region and neighboring communi-

ties,” says Brent Case, executive director.

MMIC is a satellite of the Central

Michigan University Research Corporation

SmartZone™ in Mt. Pleasant and provides

services to all industrial sectors without

targeting specific technologies.

MMIC “is an emerging economic engine

for the region,” he adds. “It is home to 17 tenant

companies, employing 130 people and gener-

ating more than $5 million in new payroll.”

MMIC operates a 112,000-square-foot

business incubator with significant support

from The Dow Chemical Co., foundations

and area universities. MMIC was instru-

mental in starting Blue Water Angels and

connected Midland-based Gantec Advance

LLC to multiple resources, including

investment/funding, marketing and public

relations, website development and office

and lab space. Gantec manufactures and

sells all natural products in the Blossom

Springs Growing System, including a plant

health supplement spray concentrate that

eliminates the need for synthetic additives

or sprays in potting soils.

“Almost all startups have a hard time thinking through and writing a good business plan. Virtually all have a particular challenge with the proformafinancials.Allhavefunding challenges.”


WEST MICHIGAN ROADMAP GUIDING COMMERCIALIZATION The West Michigan Science & Technology

Initiative (WSMTI) in Grand Rapids works

very closely with early stage inventors and

entrepreneurs, generally for pre-A round

funding to build a “commercialization” road-

map, says Linda Chamberlain, Ph.D., WMSTI

executive director. It operates a high-tech

incubator, chartered primarily for biosciences

companies.

Like other incubators, WMSTI’s relation-

ship with a nearby university, in this case

Grand Valley State, enables it to access and

leverage all university resources for its entre-

preneurs. Chamberlain says the university’s

support “is critical for sustainability.”

“The path to market is littered with more

obstacles than imagined. The costs are always

higher, things take longer than expected, and

the regulatory restraints can be challenging,”

Chamberlain says. “Success requires tenacity,

and you need to be absolutely passionate

about what you are developing.”

WMSTI has many success stories. It

helped procure a $66 million private equity

investment last year for Avalon Laboratories,

an international supplier of cardiopulmonary

vascular cannulae. In early January, Avalon

won approval from the FDA and its Canadian

counterpart to market three catheter devices

used in extracorporeal life support systems.

Last September, San Diego-based Sequenom

acquired the Center for Molecular Medicine

(CMM) – a clinical diagnostics lab in Grand

Rapids. Sequenom is fielding new genetic

tests that can detect disorders in the first

trimester of a pregnancy.

Prior to its acquisition, CMM had created

seven jobs in 18 months. With its new owner

20 more jobs will be added by mid-year and

500 more over the next five years. Sequenom

also announced collaboration with Spectrum

Health and the Van Andel Research Institute.

MLSIC BLUEPRINT FOR THE FUTURE The Michigan Life Science and Innova-

tion Center (MLSIC) provides entrepreneur-

ial support and incubator space in southeast

Michigan. Commenting when the new site

was announced last September, Roger

Newton, founder, president and CEO of

newly resurrected Esperion Therapeutics

Inc. said, “There will be a collective synergy

to having everyone together.”

FEATURE STORy

Like other incubators, WMSTI’s relationship with a nearby university, in this case Grand Valley State, enables it to access and leverage all university resources for its entrepreneurs.

Resourceful Direction forDrug DevelopmentMPI Research understands the complexities often associated with drug development decisions, and partners with Sponsors in finding innovative solutions to their development challenges.The comprehensive services offered by MPI Research include:

MPI Research is a global Contract Research Organization (CRO) that performspreclinical and select clinical studies for biotechnology, pharmaceutical, andmedical device companies. The company partners with its Sponsors in movingtheir test candidates along the regulatory pathway, in an effort to bring better,safer medications and medical products to the world.

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Publishing (eCTD) • Consulting Services

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Discovery Services • Experimental Therapeutics • Molecular Imaging • Immunology • ADME/Pharmacokinetics • Neurobehavioral Sciences • Experimental Surgery and

Device Evaluation

Bioanalytical/Analytical Sciences


Located in Northville Township, MLSIC

is a collaboration between Ann Arbor

SPARK, the economic development agency

for the Ann Arbor area, the Michigan Eco-

nomic Development Corporation (MEDC)

and the Greater Wayne County Economic

Development Corp. Esperion anchors the

incubator, which has office and lab space to

house eight to 10 small start ups at a time.

Ann Arbor-based Accuri Cytometers is

a classic case of the steps a company follows

toward success and how a center nurtures

a company through the process. Accuri de-

veloped and is now marketing a bench-top

flow cytometer and cell analysis device. It

started with licensing intellectual property

from the University of Michigan, a business

plan, grant funding that led to prototypes

and the establishment of proof of concept,

and market feasibility. Accuri has since

raised more than $20 million from venture

capital companies.

DETROIT INCUBATOR FLExING ITS MUSCLES TechTown in mid-town Detroit is the

progeny of Wayne State University, Gen-

eral Motors Corp., the Henry Ford Health

System, the Kresge Foundation, the MEDC

and the Greater Wayne County Economic

Development Corp. The incubator was

incorporated in 2000, and tissue bank start

up, Asterand, was its first tenant.

Writing in his blog, Randal Charlton,

Asterand founder and former CEO, said he

had little money and even less knowledge

about the field he was entering. “However,

I did know I was getting into a business that

would be global in scope almost immediately,”

because friends convinced him that with the

mapping of the human genome there would

be a market for biological samples for the

development of new drugs.

“Success requires tenacity, and you need to be absolutely passionate about what you are developing.”

Therearegoodfinancial

reasons for start-ups to locate in

an incubator but it’s more than

that, and the Southwest Michigan

Innovation Center (SMIC) in Kala-

mazoo is a good example.

For one thing, Western

Michigan University’s (WMU)

Bioscience Research and Commer-

cialization Center is located in the

SMIC and offers young incubator

companies access to expensive

equipment they couldn’t afford

to keep in their own inventory.

There are also tax breaks from

its location within a Michigan SmartZone™, the WMU Technology and Research Park.

Plus there’s subsidized rent and, in some instances, forgivable loans provided by

SouthwestMichiganFirsttohelpcompaniesfinishlabspace.Ifthat’snotenough,

thereistheofficespace,businessservicesandnetworkingthatoccurthere.

Since its doors opened, the SMIC has become home to over two dozen start-ups;

manybegunbyformerPfizer/Pharmacia/Upjohnemployees.Mostofthefirstcompanies

that launched in 2003 were service-based companies, like Kalexsyn, a medical chemistry

contractresearchfirm,andPharmOptima,whichprovidesdrugdiscoveryconsultingand

laboratory services. Both companies have graduated to their own facilities, as well as

AureoGen Biosciences which is developing innovative cyclic peptide-based genetic drug

engineering technologies. A fourth company, Proteos, a contract research organization

focused on peptides, has become the facility’s anchor tenant.

Thirteen companies, employing more than 200 people are currently housed in the

SMIC. Some, including pharmaceutical and medical device companies, are now locat-

ing there from out-of-state. In June 2007, Venomix, a start-up that makes insecticide

products from spider-venom peptides based on research done at the University of

Connecticut, became a tenant (see story page 41).

Emiliem, an oncology drug development company, relocated its research and devel-

opment center from Emeryville, California in October 2007. And in the summer of 2008,

Tolera Therapeutics called the SMIC home and is using research from the Cleveland Clinic

to develop innovative drugs to help reduce rejection in organ recipients.

ThispastMarch,theSMICcelebrateditsfifthanniversarywiththeopeningofan

11,000 square-foot expansion that includes HVAC renovations, nine additional laborato-

ries and a new multipurpose room with space for an additional 40 employees.

“Ours is a unique success story. The expansion highlights the foresight, generosity

and continuing support of our community to make a better place for Southwest

Michigan,” said SMIC CEO, Rob DeWit.

The collaborative partnerships that make for a successful SMIC are happening

in communities throughout Michigan, making the state a rich resource for emerging

biosciences companies.

Southwest Michigan Innovation Center a Leader

ThispastMarch,theSMICcelebrateditsfifthanniversarywiththe opening of an 11,000 square-foot expansion.

Since opening in 2003, Kalamazoo’S SouthweSt michigan innovation center haS been home to more than two dozen Start upS.



“Wayne State University gave us terrific,

purpose-built laboratories and provided

technical and other support on a consistent

basis,” he adds. At the same time, the State of

Michigan provided funding for our research

and subsidized our promotional efforts...

The result was that we added one new job a

month for the first six years of our existence.”

The icing on the cake came in 2006 when

Charlton took Asterand public. The company

is traded on the London Stock Exchange and

was its most successful stock last year.

Charlton has since re-channeled his

tremendous energies to building TechTown,

a nine-year-old incubator in a 12-block

park that stimulates job growth and small-

business creation by developing companies

in emerging high-technology industries,

including advanced engineering, biosciences

and alternative energy.

TechTown is host to 70 growing com-

panies with more than 30 high-tech start-ups

enrolling in its business accelerator programs.

WORKING TOGETHER REGARDLESS OF REGION With all these centers and a finite

number of scientists and entrepreneurs

it’s surprising that the centers don’t trip

over each other, looking for new business

opportunities. We are “competitive with

other states, but we do not compete with

other Michigan centers,” says Christine

Turner, executive director, business develop-

ment, for Ann Arbor SPARK. “We work

openly with all counties (and) cities to

promote job growth in Michigan.”

Like the other incubators, Ann Arbor

SPARK feels that its job is to help companies

be successful. If it cannot provide a service

or help, “we have many resources that we

refer companies to,” Turner adds. “We spend

a lot of time meeting and networking with

many businesses in Michigan, exactly for

the purpose of finding complimentary

providers.”

“Wayne State University gaveusterrific,purpose-builtlaboratories and provided technical and other support on a consistent basis.”

“We work openly with all counties (and) cities to promote job growth in Michigan.”

FEATURE STORy

MICHIGAN SMALL BUSINESS INCUBATORSIncubation facilities providing officeandwetlabspacetotechnology companies:

Ann Arbor SPARKAnn Arborannarborusa.org

Center for Applied Research & Technology (CART)Mt. Pleasantcmurc.com

Michigan Life Science and Innovation CenterNorthville Townshipannarborusa.org/start-ups/spark-incubator/#mlsic

Mid-Michigan Innovation CenterMidland midmichiganinnovationcenter.org/web

MTECHoughtonmtecsz.com

OUInc.Rochesterwww4.oakland.edu

Southwest Michigan Innovation CenterKalamazookazoosmic.com

TechTownDetroittechtownwsu.org

University Corporate Research ParkLansingucrp.msu.edu

West Michigan Science & Technology InitiativeGrand Rapidswmsti.org

wet labS within michigan’S incubatorS enable Start-up entrepreneurS to purSue their Science. Strategic planning, funding, training, adminiStrative Support and other ServiceS help them purSue their buSineSS.


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Researchers at the three universities have

made dazzling discoveries and awe-inspiring

breakthroughs that are advancing human

health. For example:

l A Wayne State scientist developed the anti-

cancer, anti-viral drug, AZT. The drug failed

as a cancer fighter but was found to be the

first effective drug in the battle against AIDS.

l U-M scientists lay claim to Flu Mist

nasal spray, as well as the discovery of

the gene for cystic fibrosis.

l Michigan State scientists discovered for

the first time that leptin, a hormone

produced by fat cells, supports white

blood cell production in the body,

enhancing immune function.

According to the URC, from 2002 to 2005

U-M scientists received 353 patents, result-

ing in 43 start-up companies, generating

$63.6 million in revenue. Michigan State has

received 184 patents with 28 start ups and

$105.6 million in revenue; and Wayne State

has had 95 patents and eight start-up com-

panies that have resulted in $22.9 million.

According to National Science Foundation statistics, Michigan ranks fourth in the country in terms of R&D expenditures. In 2007,

the University of Michigan (U-M), Michigan State University (MSU) and Wayne State University (WSU)

received approximately $1.4 billion in total research dollars, according to the University Research

Corridor (URC), an alliance created by the three schools to advance their mutual interests. That amount

tops total research dollars reaped by North Carolina’s Research Triangle.

RESEARCH

Michigan Universities Pack a Powerful R&D Punch

the combined experience, depth and competence of michigan

academic inStitutionS provide huge economic impetuS for the State.


In 2007 alone, U-M had 329 disclosures,

signed 91 licensing agreements and was

issued 87 patents. Michigan State had 161

disclosures, 28 licensing agreements and 35

patents.Wayne State procured 16 licensing

agreements, 45 disclosures and 22 patents.

A disclosure is the written notice of an

invention to the tech transfer office.

U-M is the state’s – and one of the

nation’s – leading research universities. In

2007-08 university research spending hit

$875.8 million, an all-time high. The school

consistently ranks among the nation’s top

five research universities, based on the

NSF’s R&D expenditure statistics.

MSU’s Vice President of Research Ian

Gray, Ph.D., says in fiscal 2008 the school

received $288 million in research support

from six sources, of which $164.2 million,

came from the federal government. WSU

research expenditures in FY 2007 were

$235.2 million, a six percent increase from

$220.7 million in 2006, says Julie O’Connor,

director of research communications.

There’s a good reason why the three state

schools can attract significant funding.

“Our scientists and our universities (go)

toe-to-toe with anyone,” says Phil Torrence,

the managing partner of Honigman Miller

Schwartz and Cohn’s Kalamazoo office.

Torrence specializes in venture capital

and mergers. In his 10 years in the field

he has worked closely with the biggies –

Stanford, Harvard, Yale and MIT.

The world of funding, research and

commercialization are indispensable to one

another; to some degree you can’t have one

without the other.

In its simplest form, a scientist comes

upon a promising drug discovery in the lab

and then applies for a patent. Next it’s time

to pursue money from the government,

private investors and university. When the

research arrives at a point where it is ready

for commercialization the school’s tech

transfer office steps in, providing all sorts of

business support while hunting for private

companies or equity companies to buy the

product’s licensing rights.

The new owner could oversee clinical

trials, further develop and take the drug to

market. If the drug is a commercial success,

some of the dollars find their way back to the

university as licensing fees. These fees are then

reinvested into the university’s research units.

Its location in

mid-town De-

troit has been a

boom for Wayne

State’s research

endeavors.“Through

our cross-campus

collaborations and

our alliances with

other institutions

such as Children’s

Hospital of Michigan,

the Henry Ford

Health System,

and our University

Research Corridor,

to name a few, Wayne

State is actively

RESEARCH

Researchers at the three universities have made dazzling discoveries and awe-inspiring breakthroughs that are advancing human health.

involved on many research fronts,” O’Connor

says. The universities provide the opportu-

nity, resources and time, but the scientists are

the heroes.

Jerome Horwitz holds a Ph.D. in organic

chemistry and was an investigator at Wayne

State for nearly 40 years until he retired in

2005. In the 1960s, while in hot pursuit of

cancer killing drugs, he discovered anti-viral

AZT and two other AIDS drugs. The drugs

failed as cancer fighters and years later the

National Institutes of Health, working with

a predecessor to GlaxoSmithKline, turned

AZT into the AIDS drug.

At the time of his discovery Horwitz was

working for the Michigan Cancer Founda-

tion with a federal grant from the National

Institutes of Health.

Simon Ng holds a Ph.D. in chemical engi-

neering and is a chemical engineering profes-

sor in Wayne State’s College of Engineering. He

is deeply involved in solving the mysteries of

biodiesel fuel production, contemplating using

a variety of low-cost feedstock for continu-

ous biodiesel production. He is director of the

National Biofuels Energy Laboratory located at

TechTown in mid-town Detroit.

Robert Freedman holds a Ph.D. in psy-

chiatry in Wayne State’s School of Medicine.

His discoveries include development of a

sensor to pinpoint the frequency of difficult-

to-track hot flashes. The sensor is less than

2 inches in diameter, weighs about an ounce

and can collect and send data on changes in

skin moisture for up to a month. He also is

studying whether use of an anti-depressant

drug has an impact on hot flashes.

University of Michigan scientists Ivan

Maillard and Yi Zhang, M.D. are looking

for ways to make bone marrow transplants

safer and more widely available. Their

approach, considered revolutionary, is un-

proven thus far, they admit. But that didn’t

stop the Damon Runyon Cancer Research

“Our scientists and our universities (go) toe-to-toe with anyone.”


John Schwartz, ph.d., developed the innovative airway rifl

you’d be surprised at the ideas you can come up with while

on vacation from work. In the case of brothers John and Rich-

ard Schwartz it was a new piece of equipment called the “Rigid

IntubatingFiberOpticLaryngoscope(RIFL),”orairwayrifle.

The RIFL enables the medical practitioner to insert an

endotracheal tube with ease, even when facing unanticipated

complications, with minimal trauma to the patient. The RIFL

is compatible with most supraglottic devices and allows for

endotracheal tube placement with or without a conventional

laryngoscope.

The beauty of Schwartz’s RIFL, says emergency medicine

specialist Mark Gulow, M.D., is its ability to navigate very

smallareasofthetrachea.Ifyouhaveadifficultairway,be-

cause the individual may have a small mouth or large tongue,

there is little room to maneuver the big blade on a glide

scope, the most common product on the market.

Gulow, who has never met Schwartz, says the RIFL is “like

acaulkinggun,…youcansqueezeittofindthevocalchords...

It snakes through the trachea, looking through the light, like in

(the movie) Fantastic Voyage. you’re slinking around and ‘whoa,’

there are the vocal chords, and you can slide the tube in.”

JohnSchwartz,whoholdsaPh.D.infisheriesandwildlife

and an undergraduate degree in engineering, recently retired

from Michigan State University. He and his brother, Richard,

the head of emergency medicine at the Medical School of

Georgia in Augusta, were sailing in the British Virgin Islands

in 2001, sipping pina coladas and bending the drinks’ straws.

Williamston Inventor Takes Aim at Airway Obstructions

The RIFL enables the medical practitioner to insert an endotracheal tube with ease, even when facing unanticipated complications, with minimal trauma to the patient.

Eureka! From that simple observation the idea of more

flexibleintubationequipmentemerged.

“(Richard) was in Special Forces at the time and told me

about the problems with intubation on patients with spinal

injuriesandbattlefieldinjuries,”Johnsays.“Ifyoucoulddo

a gentle intubation without moving the patient you wouldn’t

have to worry about spinal injuries, or injuries associated

with facial injuries.”

Later, while attending a conference in Washington, D.C., he

startedjottingdownideasandfiguredoutanintubationdesign.

Thebrothersworkedonadesignanddidalotoffield

workuntiltheyperfectedtheconfiguration.Theirfirstpatent

was issued in 2003.

Schwartz now holds three patents and 11 are pending.

Michigan State doesn’t own the patents but the university “has

been extremely helpful to us,” he says. “They arranged for a

varietyofmeetingswithpeopletheythoughtcouldbenefitus

and helped with the original business plan. Economic develop-

ment organization, Ann Arbor SPARK gave us a $25,000 grant in

the early days and an acting CEO.”

Schwartz headquartered AI Medical Devices just outside

Lansing, in Williamston, MI, and raised about

$1,750,000. The company won a 21st Century

Jobs Fund grant of $400,000 from the Michigan

Economic Development Corp., and an individual

invested $500,000 in the company. The company

has seven Michigan employees.

AI Medical began marketing the RIFL two

years ago, and has sold the product, priced

at $6,500 each, to 60 hospitals from

Florida to Alaska. Schwartz expects

thecompanytoreachprofitabilitynext

year. Last October AI Medical intro-

duced a second generation RIFL

with video that uses a camera

and an LCD monitor on the back

of the scope.

Schwartz now holds three patents and 11 are pending.


RESEARCH


MANUFACTURING

Foundation in New York City from awarding

the pair a $450,000 “Innovation Award” for

young scientists. They were two of just four

winners, selected from 198 applicants.

MSU’s Gray is reluctant to name names.

“We have many (scientists) who are nation-

ally and internationally recognized and

make major contributions to their fields,

whether it is education, environmental

sustainability, bioenergy, international

medicine, evolutionary biology, high energy

physics, and nuclear sciences,” he says.

Many of his stars work directly and

collaboratively with scientists from U-M

and Wayne State as the schools believe

strongly that working together is in their

best interests as well as those of Michigan.

The state’s other public universities

aren’t shrinking violets. Central Michigan,

Michigan Tech, Oakland University, Western

Michigan and Grand Valley State are deliver-

ing advances throughout the whole spectrum

of biosciences: health care, medicine, nano-

science, bioengineering and biotechnology,

including agriculture and energy.

And that’s just the universities. The Jay

and Betty Van Andel Research Institute

(VARI) in Grand Rapids and the Barbara

Ann Karmanos Cancer Institute in Detroit

are privately held academic research insti-

tutes highly regarded for their respective

and robust scientific programs.

Most recently, VARI announced the

appointment of Jeffrey Trent, Ph.D., as

its new Director of Research. He was

previously Scientific Director of the National

Human Genome Research Institute and on

faculty at the UM’s Comprehensive Cancer

Center. Dr. Trent will lead an expanding

VARI faculty focused on understanding the

genetics and molecular origins of cancer

and other diseases in a strategic partnership

with the Translational Genomic Research

Institute (TGen) where he also serves as

President and CSO.

Karmanos is one of 40 NCI-designated

comprehensive cancer centers in the U.S.

It cares for more than 6,000 new patients

annually and conducts more than 700

cancer-specific scientific programs and

clinical trials, second only to the M.D.

Anderson Cancer Center in Houston, TX.

Without a doubt, Michigan’s academic

research institutions generate innovation,

new technologies and commercialization

ventures, a huge economic force for the state

and much of it focused on the biosciences.

RESEARCH

“We have many (scientists) who are nationally and internationally recognized and make major contributions totheirfields...”

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In 2001 President Bush, following Michigan’s lead, pro-

hibited government funding of embryonic stem cell research.

Existing and limited stem cell lines were basically grandfa-

thered in. Scientists with private support were able to work

on embryonic stem cells while others headed overseas where

there were no restrictions and a warm reception.

Michigan faces some barriers in attempting to become a

center of embryonic stem cell excellence. “It will take more

than changing the law,” Cibelli says. “We have to attract

capital to come here rather than to California, Massachusetts,

Connecticut and New Jersey. Cibelli says the impact of the

federal dollars is “good for researchers.”

Thefirststepisgettingthebrainpowerhere,headds.

“All we need to do is create a critical mass of scientists, then

the investment will trickle in.”

Michigan State’s stem cell research budget is funded by

the university, private donations and a smaller portion from

the federal government.

The passage of Proposal 2 was a catalyst to establish the

WayneCountyStemCellCommercializationCenter,thefirst

such center in Michigan, says Carol Brenner, a stem cell scien-

tist at Wayne who holds a Ph.D. in reproductive biology.

Michigan voters decided last fall to ease restrictions on

embryonic stem cell research. The vote was vindicated when

President Barack Obama signed an executive order expanding

federal funding for embryonic stem cell research and dishing

out millions of dollars to the nation’s top universities delving

into the potential of stem cells.

Michigan has been out of the embryonic stem cell business

foradecade,havingbeenoneoffivestateswithstrictrestric-

tions in place. Now the prospects for new money can propel

thestateinthefield.

“We are playing catch up…you can’t do it overnight;”

says Sean Morrison, Ph.D., research professor and director

of the Center for Stem Cell Biology at the University of

Michigan’s Life Science Institute (LSI). “It takes time to

overcome the competition from other states. We aren’t

coming from a standing start [though]. We were walking

slowly when everyone was running.”

Last fall 53 percent of state residents voted in favor of

Proposal 2 to lift the ban on stem cell research that dates back

to 1978. Proposal 2 allows the donation of embryos produced

in fertility clinics that would otherwise be discarded, and

permits researchers to create embryonic stem cell cultures

to study disease.

“It’s great that the people of Michigan were able to

remove this hurdle,” said Jose Cibelli, of Michigan State

University and holder of a Ph.D. in reproductive physiology.

Until the passage of Prop 2, Cibelli was working with stem cells

from monkeys and those approved by President Bush in 2001.

RESEARCH

Michigan Proposal 2 Passage Resurrects Embryonic Stem Cell Research in the State

Last fall 53 percent of state residents voted in favor of Proposal 2 to lift the ban on stem cell research that dates back to 1978.

with embryonic Stem cell reSearch bacK in the mix, u of m’S center for Stem cell biology director, Sean morriSon, ph.d., iS upbeat about michigan’S

ability to maKe Significant breaKthroughS in the area.

25 BioMatters | Spring 200925 BioMatters | Spring 2009BioMatters | Spring 2009

The center is the brainchild of Wayne County

Executive Robert Ficano and is a partnership

between Wayne County, Wayne State and Smart-

Zone™, TechTown. The 2,500-square-foot research

facility lab already has a two-year, $2.9 million

financialcommitmentfromWayneCountyfor

laboratory construction, equipment and manage-

ment, and $1.5 million from Wayne State. Wayne

State has challenged TechTown to raise matching

funds. It also will serve as a site for academic

ventures.

The center will allow Wayne State to trans-

late basic research into commercial products.

“We are looking to collaborate with scientists

and research universities internationally,” says

Randal Charlton, executive director of TechTown,

who adds that the lab is in early-stage discussions

with stem cell research teams in Sweden, Great

Britain and Hungary.

The lab is particularly valuable to small start-

up companies that rarely have the capital to afford

the space and high-tech equipment that will be provided,

Charlton adds.

Brenner joined Wayne State nearly two years ago. Her lab has

focused on human embryonic stem cells and primate reproduction.

Thanks to Prop 2 passage “our lab is now expanding to…areas of

reproductive research using human embryonic stem cells that have

not been approved for NIH funding (previously).”

Brenner was at Louisiana State in New Orleans working in

a technology park when Hurricane Katrina ripped through the

city in 2005, essentially closing down Brenner’s lab. She worked

withWSU’sBarryBavister,bestknownfordevelopingthefirst

reliable procedures for IVF in monkeys prior to being recruited

to Wayne State.

TodayBrenner’sscientificteamiscollaboratingwithUCLA,

doctors and scientists in the neurology area and has set up the

Primate Center in Puerto Rico to do monkey IVF. It is getting a NIH

grant to start making monkey-induced pluripotent stem cells for

clinical translational studies.

Morrison believes scientists at U-M,

Wayne State University and MSU will

more than carry their weight in the

field.“Itwilltakeeverybodytopush

thisfieldforward,andscientistsat

multiple institutions within the state are

capable of making breakthroughs.”

The easing of restrictions on stem

cell research makes it possible for UM

to develop its own new embryonic stem

cell lines to study, notably in the neuro-

degenerative diseases, such as Hunting-

ton’s disease.

Towards that goal, in mid-March

the U-M announced the formation of the

A. Alfred Taubman Medical Research

Institute Consortium for Stem Cell Ther-

apies. The Consortium will be among

thefirstgroupsinthecountrytoderive

new embryonic stem lines that are

linked to a database containing genetic

and medical history information about

donor embryos and families. This should

enable researchers to better understand

how disease genes have manifested

themselves over generations. Before

Obama lifted the ban, Michigan was one

of six exploratory centers funded by the National Institutes of

Health to conduct embryonic stem cell research.

PassageofProposal2hasalreadyhadasignificantimpact

on recruiting embryonic stem cell scientists to U-M. “Hiring new

faculty members takes months when you’re searching for the

best people in the world,” Morrison says. The LSI started the

recruiting process last September in anticipation of Proposal 2’s

passage, and there are now plenty of resumes to choose from.

For a long time it was rumored that Morrison could leave

the university because of the embryonic stem cell ban.

“I stayed here because Michigan is a spectacular place to do

research,” he says. “I would hope to have my cake and eat

it, too. I hope to be able to develop this environment into all

areas of stem cell research.”

Michigan shares this “can-do” attitude and is poised to

greatlyexpanditspresenceandimpactinthefieldofstem

cell research.

Thefirststepisgettingthebrain power here…“then the investment will trickle in”

“it will take everybody to push this field forward, and scientists at multiple institutions within the state are capable of making breakthroughs.”

embryonic Stem cellS provide a potentially renewable Source of replacement cellS and tiSSueS to treat diSeaSeS.


Realizing the Promise of Tomorrow’s Leaders

For more information go to: www.bme.umich.edu/industry

The University of Michigan Department of Biomedical Engineering (BME) works closely with industry and business to help improve products and techniques. We also provide several opportunities for you to support and build relationships with talented BME students who will be future leaders in the field. Find out how you can:

• Support our Design Program, sponsor a project, mentor students• Recruit BME students for internships and staff positions• Participate in our BME Career Fair and other events

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LIFE SCIENCES ATTORNEYS


RESEARCH

Students Collaborate to Give the Gift of LifeRESEARCH

For the past four years 15 students at Michigan Tech

University in Houghton, MI, have been building a better

mousetrap to improve the quality of CPR administered

in hospitals.

Their majors are in engineering, technical communi-

cations,management,marketingandfinance,andtheir

finishedproductistheCPRMattress,afoammattressthat

deflatesquicklytoprovideafirmsurfacetomakeCPR

moreeffective.Thefirmerthesurfacethemoreefficient

the compression.

The current generation of foam mattresses, most

commonly used in hospitals, is activated by patient

pressure and uses air valves to diffuse the mattress.

“We could be in the market as close as the end

of this year,” says Laurilee Kroll, an MTU student and

directoroffinanceandmarketingforTechInitiatives,

the S corporation created to sell the CPRMattress.

The students are working with the help of MTU facul-

ty and the Houghton SmartZone™, one of 15 state-backed

locationswheretechnology-basedfirms,entrepreneurs

and researchers take advantage of commercialization

resources.

Medical research studies over the past eight years

have shown that the depth and rate of compressions

being performed are not meeting the standards set forth

by the American Heart Association. Thus, in 2005 the

Cardiopulmonary Division of Portage Health Hospital

in Hancock approached MTU’s biomedical engineering

department,askingthemtofindoutwhyCPRwas

proving ineffective in hospitals and led to a large number

of deaths.

The faculty and students found that the problem

rested with the quality of existing foam mattresses upon

which medical personnel administered CPR to patients.

The students found that when CPR is performed on

a patient lying on a foam mattress, the CPR provided 41

percent of the compression needed to resuscitate the

patient; when a CPR board was placed under the patient

theefficiencyincreasedto53percent.Theideabehind

the CPRMattress was born.

When the CPRMattress is activated a vacuum motor

removes the air in the upper half of the mattress, causing

the foam mattress to compress into a rigid surface. The

vacuum will cycle again to make sure the mattress retains

its rigidity. When the mattress is no longer needed it can

bere-inflatedbypushingandholdingtheactivationbut-

ton for 2 seconds. The mattress returns to full comfort

level within one minute. This technology is adaptable to

virtually any foam-based mattress.

“It’s a good concept,” says Luretta Pandya, an RN

and strategic clinical sourcing manager for the Detroit

Medical Center. DMC nurses have crash carts with boards

anddefibrillatorstoadministerCPRwhenapatientgoes

into cardiac arrest. “[With the CPRMattress], you press a

buttonanditdeflatesin10secondssothepatientcanbe

resuscitatedonafirmsurface.Youdon’thavetomanipulate

the patient to the right position to improve compression.”

PandyabelievestheCPRMattresswouldbebeneficial

for medical surgical and critical care patient populations.

Kroll says the standard hospital air mattress ranges in

price from $500 to $700, while the CPRMattress will cost

from $2,000 to $2,500.

Afterthestudentsfinishedtheirresearchinearly

2007, the project was heading for the shelf because

further support was needed for commercialization, Kroll

says. Then the SmartZone™ stepped in. It incorporated

Tech Initiatives, made the students equity partners

developed by StudentS at michigan tech univerSity, the cprmattreSS deflateS in 10 SecondS So a patient can be reSuScitated on a firm Surface.

Mattress Compression Efficiency

COMPRESSION EFFICIENCy PERCENTAGE


and helped them apply for a patent in 2007.

“Each student has been given stock in the company

based on their input in the project,”

Kroll says. “We work for half payment

and half equity.”

The Houghton SmartZone™ is

now talking to a number of local and

national medical equipment companies,

including Stryker Corp. in Kalamazoo

and medical bed manufacturer,

Batesville, IN-based Hill-Rom about

a licensing agreement, Kroll says.

TOPICS TO INCLUDE: Synthetic Biology • Pharmaceutical

Manufacturing • Advanced Biofuels • Food Ingredients

& Flavorings • Fragrances & Cosmetics • Biopolymers

• Renewable Chemical Platforms • Fine Chemicals

from Biomass • Biomass Pretreatment • Biotechnology

for Climate Change • Ethanol & Cellulosic Ethanol •

Biodiesel • Microbial Fuel Cells • Energy from Algae •

Use of Agricultural & Forestry Residues • New Energy

Crops • Feedstock Collection • Cell Wall Modifi cation

• Enzyme Development • Health & Personal Nutrition •

New Business Models

FOR MORE INFORMATION PLEASE VISIT US AT WWW.BIO.ORG/WORLDCONGRESS.

PHONE: 202.962.6630 EMAIL: [email protected]

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Initsfirstthreeyearstheprojectwasfunded

completely by grants totaling $150,000, coming from

the state of Michigan and private

investors. “Our future plans are to

get the mattress into clinical trials

and entertain offers for licensing

agreements with current medical

mattress manufacturers,” Kroll says.

Currently the CPRMattress is in

itsfinaldesignphaseandisabout

to go through further testing by

Underwriters Laboratories Inc.

Currently the CPRMattress is initsfinaldesignphaseandis about to go through further testing by Underwriters Laboratries Inc.

Save the Date5th Annual MichBio Expo & ConferenceTuesday, November 3 & Wednesday, November 4, 2009Radisson Plaza Hotel, Kalamazoo

PLAN TO ATTEND THE PREMIER BIOSCIENCES EVENT IN MICHIGAN CONFERENCE HIGHLIGHTS •Concurrentcross-sectortracksinR&D, Emerging Business, Medical Affairs and Markets •CEODinnerForum •Businesspartneringmeetings •Biosciencelegislativeaffairs •Newtechnologyandemergingcompany presentations •ExhibitHall •Facilitytoursandmuchmore! Over 70% of attendees are biosciences executives

ExHIBITOR/SPONSOR INFORMATION & RESERVATIONSContact [email protected]

RESEARCH


The Pharmaceutical Research and Manufacturers of America

PhRMA MEMBER COMPANIES ARE COMMITTED TO SUPPORTING ECONOMIC GROWTH & FURTHER RESEARCH

THAT LEADS TO GOOD JOBS & THRIVING COMMUNITIES.

ECONOMIC DEVELOPMENT

Governments Building Foundations for Regional Bioscience Growth




Local governments are aggressively establishing biosciences enclaves, as they view the sector’s growth potential amid challenging economic times. Partnerships have been created, resources commit-

ted and incentives provided to lure biotech companies to their areas or to nurture new and exisiting

companies.

BIOSCIENCE IS BIG BUSINESS IN WAyNE COUNTy Wayne County’s economic development

unit has created partnerships, granted

money and reached out to biosciences

professionals, all aimed at growing

biosciences’ presence in the area.

At the 2008 MichBio Expo last November,

county executives huddled with Michigan’s

biosciences professionals to learn first hand

about the industry’s challenges and opportu-

nities. This was one more county strategy

to further hone its life sciences business

attraction efforts, says Todd Fenton,

executive manager of the Wayne County

Land Bank Corp.

Last summer Wayne County, along with

the Michigan Economic Development Corp.

(MEDC), Ann Arbor SPARK (see story 34),

the Michigan Life Science and Innovation

Center (MLSIC) and others opened what it

considers to be a cutting edge wet lab incu-

bator in Plymouth Twp. on property vacated

by Pfizer Inc. It scored a major coup when

Roger Newton moved his second generation

Esperion Therapeutics into a portion of the

57,518 square foot building.

In addition to its MLSIC collaboration,

Wayne County has:

l Created a partnership with TechTown

in mid-town Detroit to create the Wayne

County Stem Cell Commercialization

Center. (See story page 24.)

Spanos rattled off numerous existing

ones, such as Somanetics, Delphi Medi-

cal Systems, Housey Pharmaceuticals and

Rockwell Medical Technologies. And

that’s not counting Beaumont Hospitals,

a research giant that is now flexing its

muscles in commercialization through its

Beaumont Commercialization Center.

None of the county’s goals would be

possible without a world-class workforce.

Officials work closely with local school

districts and area colleges/universities to

ensure students are learning 21st century

skills. Oakland Community College has a

promising bioscience-focused curriculum.

OAKLAND COUNTy SEES BRIGHT FUTURE FOR BIO JOBS The future belongs to high tech, and

Oakland County Planning and Economic

Development knows that that’s where its

future has to be.

In late 2004 the county created the

Emerging Sectors Strategy, identifying

10 emerging industries ripe for nurturing.

Biosciences and health care were two of the

10 and today are the fastest growing sec-

tors in Oakland County, says Irene Spanos,

the county’s senior business development

representative.

The county boasts 4,324 biosciences

and medical-related facilities, including

hospitals, nursing homes, pharmaceuticals,

medical devices and medical office building

clusters. Knowing a good idea when it sees

it the county recently launched Oakland

County Medical Main Street, an effort to

brand Oakland County as a “medical tour-

ism” destination.

“We want to brand southeast Michigan as

a biosciences hub,” Spanos says. The county is

projecting the sector will create 45,000 jobs by

2018. It employed about 10,500 people last year.

The county uses its existing trade mis-

sions as well as exhibiting at many technol-

ogy conferences regionally and throughout

North America, Europe and Asia, to hunt for

new partnerships.

Oakland County already has an impres-

sive line-up of biosciences companies.

“We want to brand southeast Michigan as a biosciences hub.”

an expanding liSt of reSearch facilitieS now reSide in the quadrant Known aS grand rapidS’ medical mile, where there haS been $1 billion worth of inveStment in recent yearS. it began with the founding of the van andel inStitute (above) by Jay and betty van andel in 1996 and haS Since Spread to include grand rapidS community college’S calKinS Science center, Spectrum health’S butterworth hoSpital complex, grand valley State univerSity’S cooK-devoS center for health ScienceS, and the michigan State univerSity Secchia center medical School, among otherS.


l Announced a $750,000 construction

grant to the TechTown business

incubator. This grant will enable

TechTown to build out 10,000 square

feet of office and laboratory space

on its third floor – enough for nine to

12 new tenants.

l Made available a pool of $250,000 of

grant money for start-up companies

located in the MLSIC Plymouth

Township building.

For all the activity, commitment and

energy throughout the state, life sciences

professionals know what Fenton knows,

“Life science is not a panacea to cure all our

woes; it is crucial because it’s high tech and

attracts highly educated people. Even if it was

something that we didn’t have to do we would

still do it.”

RIGHT PLACE IS RIGHT FOR GRAND RAPIDS The Right Place Inc. in Grand Rapids has

the right stuff for western Michigan. At 24

years old it is a leader in regional collabora-

tion, luring new biosciences companies into

western Michigan and bolstering existing

ones through a myriad of overlapping rela-

tionships.

For example, The Right Place formed

a partnership with the West Michigan

Science & Technology Initiative (WMSTI)

that, in turn collaborates with the Van

Andel Research Institute, Grand Valley

State University, the City of Grand Rapids

and Grand Rapids Community College.

The partnership has recently expanded

to include Spectrum Health, Saint Mary’s

Health Care, Mary Free Bed Rehabilitation

Hospital, the Grand Angels and Michigan

State University College of Human Medicine.

The relationships are complex, but

The Right Place’s vision is simple:

l Lead West Michigan business

development efforts.

l Identify and develop emerging growth

opportunities.

l Strengthen the global competitiveness

and innovation of existing regional

manufacturers.

One of The Right Place’s biggest accom-

plishments was recruiting Sequenom Inc. to

the region from San Diego in 2008. Seque-

nom provides genomic and genetic analysis

solutions for the research and molecular

diagnostic markets.

The Right Place played an “integral

and critical role” in the process of creating

the Medical Mile in downtown Grand

Rapids, says Tim Mroz, senior director of

communications. “We provided economic

development support to the city as well as

public and private developers.”

The Right Place and Kalamazoo

neighbor, Southwest Michigan First, often

work together. In 2007 the pair co-funded a

thorough study of the biosciences industry

in West Michigan. From there they devel-

oped “A 2007 Study on ‘Regaining Global

Prominence in the Life Sciences in Western

Michigan.’” The study focused on biotech,

medical devices and pharmaceuticals.

The results of this study and execution

of the plan helped fuel the existing West

Michigan’s Life Science corridor, Mroz says.

SOUTHWEST MICHIGAN PUTS BIOSCIENCE GROWTH FIRST The mission of Southwest Michigan First

(SWMF) “is to create jobs and wealth in the

Kalamazoo region,” says Heather Smith, vice

president. The nine year-old private, non-

profit organization has assisted more than

120 organizations with retention, expansion

and recruitment projects. It has overseen 26

bioscience company start-ups and funded 10

companies through its venture fund. It cre-

ated more than 5,000 jobs in 2008, according

to its website.

One of SWMF’s best tools is the South-

west Michigan First Life Science Fund.

SWMF established the $50 million fund in

2005 as a limited partnership venture fund

to invest in early-stage bioscience compa-

nies. Smith says the fund is believed to be

the largest sum of community-based private

capital ever to be raised and managed by an

economic development organization.

The fund only invests in companies that

already have a presence or are committed

to establishing a presence in Southwest

Michigan, Smith says, such as Redmond,

Washington-based Micronics Inc. Micronics

is setting up its headquarters and produc-

tion, distribution and customer support

operations in Kalamazoo for the medical

devices it is developing to speed up genetic

testing.

“We work with existing companies within

our region to expand their opportunities,”

Smith says. “For fund companies…we provide

assis-tance in helping them find partnership

opportunities, executive leadership and physi-

cal space.”

Working with The Right Place, SMF has

“forged a strong networking base with the

Officialsworkcloselywithlocal school districts and area colleges/universities to ensure students are learning 21st Century skills. Oakland Com-munity College has a promising bioscience-focused curriculum.

Wayne County’s economic development unit has created partnerships, granted money and reached out to biosciences professionals, all aimed at growing biosciences’ presence in the area.


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Israeli life science market,” she says, to

pursue partnerships with biosciences com-

panies looking to locate in the United States.

To date, the two organizations have met with

almost 60 companies and four incubators.

LANSING AREA GETS BOOST FROM LEAP In 2007 private sector leaders in Greater

Lansing realized they needed better collabo-

ration to strengthen the region’s economic

development efforts. Thus emerged LEAP,

a public-private partnership, providing

companies in Ingham, Eaton, and Clinton

counties with the tools they need to succeed.

Michigan State University is the key partner

in the collaboration.

LEAP has 36 investor partners who are a

“who’s who” of the region and state, including

the Sparrow Health System.

Biosciences in total remains “big

business” in Michigan, accounting for

nearly 100,000 direct and indirect jobs. It

generates $9.34 billion in economic impact,

according to a recent study commissioned

by the Washington, D.C.-based Pharma-

ceutical Research and Manufacturers of

America and released by MichBio. The study

concludes that Michigan has abundant

assets to support and grow the biosciences,

particularly in the presence of its major re-

search universities and associated initiatives

throughout the state.

OPEN SOURCE APPROACHOPENS MARKETS FOR ANN ARBOR SPARK

“Economic development in Michigan

should take a page from the playbook of

the ever-evolving software industry. Its

“open source” philosophy—the source code

that drives development should be open

and available to all—is a model that can

propel Michigan’s Life Science industry

success in growing, retaining, and attract-

ing business,” says Michael A. Finney, Ann

Arbor SPARK CEO.

Ann Arbor SPARK has taken steps to pilot this approach to economic development

by designing initiatives and committing resources that are meant to be openly available

and shared statewide. These resources include business incubation, talent enhancement,

pre-seed funding, and cross-region assistance with development projects.

There are several economic programs that are “open source” and currently

delivering jobs, talent and other resources to Michigan:

l Michigan’s SmartZone network has provided the infrastructure needed to attract,

retain and grow business.

l The Michigan Life Science and Innovation Center (MLSIC) is a state-of-the-art wet

lab incubator developed collaboratively with the Michigan Economic Development

Corp. (MEDC), Wayne County Economic Development, Esperance Family Foundation,

New Economy Initiative of Southeast Michigan and Ann Arbor SPARK’s Foundation

(also see story page 31).

l The Michigan Pre-Seed Fund Capital Fund, a collaborative effort among Michigan’s

SmartZone network, has provided nearly $5 million in funding to 30 emerging

technology businesses.

l The Michigan Innovation Equipment Depot, a partnership between Ann Arbor SPARK,

MichBioandPfizer,andsupportedbytheMEDC,hasprovidednearly$6millionin

high-value repurposed laboratory equipment and supplies to emerging life sciences

companies across the state.

l The Economic Development Coalition of Southeast Michigan (members include

southeast Michigan economic development organizations) is working with local,

state, and federal government to secure necessary funding to support activities

of the six business accelerators within Southeast Michigan.

WiththedeclineinmanufacturingandlossofPfizerjobsintheAnnArborregion,

talent initiatives have been a cornerstone of economic development efforts. Programs

like Hot Shots, that connects employees and employers in a fun “happy hour” format,

or Mingle & Match, a sort of “speed-dating” for start-ups and potential employees,

have been highly effective in supporting the retention of talent in our region and

placing high-value knowledge workers in growing companies.

A steady stream of entrepreneurs seeking ways to accelerate their business provides

impetus for regional economic development activities. Programs like Entrepreneur Boot

Camp are foundational resources for new businesses; BioArbor, a monthly education

and networking series, and the Annual Collaboration for Entrepreneurship showcase

the entrepreneurial success needed to support Michigan’s new economy. Leveraging

educational resources throughout the region is integral to economic development. Ann

Arbor SPARK’s partnerships with the University of Michigan, Eastern Michigan University,

Washtenaw Community College and the University Research Corridor have increased the

success of technology transfer and kept valuable knowledgeable workers here in the

community — creating, innovating and thriving.

Biosciences in total remains “big business” in Michigan, accounting for nearly 100,000 direct and indirect jobs. It generates $9.34 billion in economic impact.

The study concludes thatMichigan has abundant assets to support and grow the bio-sciences, particularly in the presence of its major research universities and associated ini-tiatives throughout the state.

michael finney (left) iS preSident & ceo of ann arbor SparK.




For example it partnered with economic development

organizations in Ann Arbor, Holland and Kalamazoo to

retainPfizertalentandassetsthroughtheCompanyFor-

mation and Growth Fund. The MEDC channeled $12 million

from Michigan’s 21st Century Jobs Fund to the three or-

ganizationsthat,inturn,determinedwhichformerPfizer

scientists would receive free or be able to buy equipment

to start their own companies. Scientists received small

equipment at no cost, and leased larger lab equipment.

The 21st Century Jobs Fund is the state of Michigan and

MEDC’smarquisprogram.Statemoneyflowsintothefund

to support entrepreneurs creating biosciences companies

at every stage of development. Recipients also include

strategic services partners that can help start ups apply

for government grants and learn how to commercialize.

In November 2005 the state used the tobacco settle-

ment money and created the 21st Century Jobs Fund which

“absolutely”fillsthevoidleftbytheinstitutionalinvestors,

Cindy Douglas, vice president of technology development

for the MEDC told x-ology magazine in the fall. “We need

a continuity of capital to fuel the economy and we need

more than traditional banking sources,” she added.

Since 1999 the Jobs Fund, and its predecessor, the

Life Science Corridor Program, have disbursed $323

millionintheformofconvertibleloanstofor-profitcom-

paniesandgrantstonon-profitorganizationsforapplied

and basic science, and commercialization.

COMMERCIALIZING TO SUCCESS In the arena of partnership-building, MEDC also works

“with universities to pull products out of the lab” and with

the venture capital community “to leverage funding to

support the emerging technology,” adds Viges. “We started

SmartZones™ (see map page 10) that had business and sci-

ence resources, notably incubators and wet labs,” to provide

scientists with the environment to grow their technology.

The state created SmartZones™ with tax incentives.

SmartZones™ “establish Local District Financing Authorities

(LDFAs) where private companies pay taxes and the LDFA

captures those taxes that come back to us,” says Fred

Einspahr, former president and CEO of the Southwest Michigan

InnovationCenter(SMIC)inKalamazoo.“NonprofitsinSmart-

Zones™ don’t pay personal property tax on their equipment.”

MEDC offers MEGA tax incentives based on job creation

and retention for all businesses. The state also has a


MEDC Shepherds State’s BiosciencesThe MEDC has created many programs to grow the industry, but what it all boils down to

is relationship building and investment, says Kapila Viges, managing director of program

administration for MEDC.

MEDC offers MEGA tax incentives based on job creation and retention for all businesses.


technology commercialization credit for all 21st Century Jobs

Fund competitors, as well as an angel fund tax incentive.

Last year these tax incentive plans paid off. “We had

the busiest year we ever had in getting tax incentives,

which means companies are expanding,” Viges says.

MEDC also invests in the 21st Century Investment Fund,

and Venture Michigan Fund, both part of the 21st Century

Jobs Fund. These are funds of funds, investing in venture

capital funds that invest in Michigan companies.

Overall, since 1996 the state has invested more than

$45 million in venture funds that in turn funded biosciences

companies. A total of $35 million of that amount has come

since 2006, a sign that the state is serious about a multilat-

eral approach to supporting entrepreneurial ventures.

MEDC COMMITS $200 M TO EqUITy MARKETS Ann Arbor-based HealthMedia Inc., which designs web-

based software that helps people manage certain diseases,

behavioral problems or general wellness issues, is a good

example of how state investment works.

In 2003-04, the MEDC was one of many organiza-

tions that invested a total of $24 million in Arboretum

Ventures, an Ann Arbor venture capital fund, which in

turn invested an undisclosed sum in HealthMedia. Last

year Johnson & Johnson Co. bought HealthMedia, seeing

itasaperfectfittoitsexpandinghealthcareplatforms.

Despite the state’s current economic woes, the

MEDC knows a good investment when it sees one. In the

next few years the state and MEDC will invest a total of

$200 million in equity markets in Michigan. The money

will come from the state’s Venture Michigan Fund, as

well as the 21st Century Investment Fund. Douglas

expects that $75 million will be placed annually in the

21stCenturyJobsFundthroughfiscal2015.

MEDC is banking heavily on the future of biosciences

in Michigan.


In the next few years the state and MEDC will invest a total of $200 million in equity markets in Michigan.


BioMatters Tells Michigan’s Biosciences Story Tell us what you’d

like to seel Topics you’d like coveredl Companies that are on the leading edgel Collaborations that workl People making a differencel How-to Informationl Guest opinion topics

NExT ISSUE: November 2, 2009 CONTENT DEADLINE: August 3, 2009

Send ideas to: [email protected]

Intellectual Property

Design Engineering

Usability Testing

Prototyping

Clinical Trials

FDA Approval

It’s just what the doctor ordered.

Anyone who has ever had a good idea knows you can’t nurture it alone. It takes a hospital. One that can help turn your idea into a breakthrough. Introducing the Beaumont Commercialization Center, with the resources to handle everything from prototyping to clinical trials. And everything in between. Because at Beaumont, we live for good ideas. Where ideas go to get better.

BioscienceWarner’s Life Sciences Group has the diverse talent required to bring your product or idea all the way from patent stage to commercial market. To get started, call Amy Rinaldo at 248.784.5107.

A better partnership.

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Michigan has an abundance of raw materials necessary for a vibrant bioeconomy.

State Expects to be Sitting on Top of an Eco-Friendly World

TECHNOLOGy

38BioMatters | Spring 2009 38BioMatters | Spring 2009


OBT’s mission is to identify, encour-

age and support research programs that

will position the university as a worldwide

standard-bearer for the bioeconomy. To

that end it functions as a coordination and

communication office, assisting scientists in

obtaining grants and contracts and building

bridges to other universities, companies,

and governmental agencies.

The terms “bioeconomy” and “biobased

economy” describe a future where people

rely heavily on biomass, the fuel of the

future. Biomass is a renewable resource

composed of plant material and municipal

and livestock waste that can be converted

into electricity, fuels and plastics, as well as

the basic components of chemical processes.

“MSU conducts a broad range of basic

and applied research to answer critical

questions about the bioeconomy,” says Steve

Pueppke, director of the OBT at MSU.

In 2007 the Department of Energy

awarded MSU and the University of Wis-

consin $135 million over five years to create

Michiganscientistsarerackingupsignificantdiscoveriesonthe road to developing the bioeconomy, and Michigan State University,

along with Midland-based Dow Chemical Co., among others, are leading the way. Three years ago

universityPresidentLouAnnaSimoncreatedtheOfficeofBiobasedTechnologies(OBT)topropel

school research and resources aimed at fostering connections with public and private sector

initiatives designed to expand Michigan’s bioeconomic sector.

the Great Lakes Bioenergy Research Center

(GLBRC). The GLBRC funds projects led by

dozens of MSU faculty members.

The MSU discovery of a plant protein

— trigalactosyldiacylglycerol 4, or TGD4 —

last summer by Christoph Benning, Ph.D., a

professor in the department of biochemistry

and molecular biology, holds great com-

mercial promise.

Benning identified TGD4 as a protein

necessary for chloroplast development.

Chloroplasts, in plant cells, convert sunlight,

carbon dioxide and water into sugars and

oxygen for the plant during photosynthe-

sis. Understanding how the protein works

could allow scientists to create plants that

would be tailored specifically to produce

biofuels, possibly making the process more

cost-effective.

Benning’s work was funded by the

Energy Department and the National

Science Foundation to the tune of nearly

$1 million over the course of three years.

Just below the Arctic Circle, Kris

Berglund, MSU biochemical processing

researcher, is collaborating with scientists

at the Luleå University of Technology in

Sweden on products and processes that may

play a crucial role in furthering Michigan’s

bioeconomy.

Berglund’s research has spawned enter-

prises in Michigan, Sweden and France, and

raised tantalizing possibilities for diversified

biorefineries that crank out bioproducts

ranging from fuels to chemicals.

Working Bugs, LLC, an East Lansing-based

company, and its Swedish counterpart, Work-

ing Bugs AB, were co-founded by Berglund.

The companies identify microbes that could

be used in fermentation processes to make

products from renewable resources, as well

as intermediate chemicals that are then used

to make other biobased products.

OBT’s mission is to identify, encourage and support research programs that will position the university as a worldwide standard-bearer for the bioeconomy.

Berglund’s research has spawned enterprises in Michigan, Sweden and France, and raised tantalizing possi-bilitiesfordiversifiedbio-refineriesthatcrankoutbioproducts ranging from fuels to chemicals.

mSu reSearcherS bruce dale and mariam SticKlen (above), have genetically engineered corn varietieS to produce the enzymeS needed to breaK down celluloSe and hemicelluloSe into Simple SugarS that can be fermented into ethanol.


TECHNOLOGy

PLANT GENETICS, CROP PROTECTION DOMINATE DOW RESEARCH For more than a decade Dow Chemical

Co., primarily through its subsidiary

Dow AgroSciences, has been working in

the field of plant genetics and sustainable

processing technologies for crop protection,

pest and vegetation management, seeds,

traits, and agricultural biotechnology. Dow

AgroSciences has a facility in Harbor Beach,

MI that employs 90 people devoted to

manufacturing spinosad and spinetoram that

are active ingredients in several insecticides

consisting of naturally derived substances

created through a fermentation process.

The EPA presented Dow AgroSciences

with its Presidential Green Chemistry

Challenge Award in 2007 for developing

spinetoram.

The company has joint ventures strung

out worldwide, as well as domestically. It

has a joint venture with a Brazil company to

manufacture polyethylene from sugar cane.

The resulting ethylene will create ethanol.

Working with the U.S. Department

of Energy’s National Renewable Energy

Laboratory, Dow is developing a process that

could convert biomass to ethanol and other

chemical building blocks.

Dow AgroSciences has developed and

received federal regulatory approval for the

world’s first plant-made vaccine, Concerta,

which contains no animal components and

offers important safety advantages over

conventional vaccines.

Future goals include improving crops,

enabling lower cost feed stocks; bio-based

routes to replace existing molecules; create

new molecules; and both biotech and ther-

mochemical conversion technology.

michigan’S plentiful natural reSourceS could Support the growth of dedicated biomaSS cropS.

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TECHNOLOGy

Spidersarescarycreatures,especiallyifyou’reaflyormosquito.

Those insects never have a chance against the venomous peptides

spiders emit to kill them. So if you’re looking for ways to kill insects

without harming humans and animals why not capture those same

toxins?

That’s precisely what John McIntyre, Ph.D., is doing in Kalama-

zoo. McIntyre boasts an impressive 30-year career in agricultural

biotechnology, including operational experience in the development

and commercialization of specialty agricultural products.

President and CEO of Venomix Inc., and working within the

Southwest Michigan Innovation Center (SMIC), McIntyre is developing

technology licensed from the University of Connecticut Research and

Development Corp. (UCRDC).

“Wethinkwearetheleadersinthefieldindevelopingenviron-

mentally compatible insecticides for this century,” he says.

Following 10 years in senior management at Ecogen Inc., McIntyre

moved to Michigan in 1995 as president and CEO of Emerald BioAgri-

culture Corp., formerly Auxein, in Lansing.

An Oregon native, McIntyre says he’s “always looking for exciting

opportunities” and found one while doing an online search in 2005

when he came upon UCRDC information. He contacted UCRDC,

he says, looking for someone “to get the ball rolling,” to create

Venomix. “We found each other.”

Through networking McIntyre met Patrick Moran, managing

director of Southwest Michigan First Life Sciences Fund. The next

step was falling under the wings of SMIC.

So far Venomix has raised $6 million in the form of an R&D licensing

agreement with Chemtura Corp., a $3 billion chemical company in

Middlebury, Conn.

Levi Littell Herbst & Co., an investment banking boutique in

Chicago, was a consultant to Southwest Michigan First and wrote an

introductory letter for Venomix in anticipation of the company trying to

raise $8 million in Series B funding. Venomix is now starting the fund-

raising process and hopes to close in the fourth quarter, McIntyre says.

In its letter, Levi Littell says insects are becoming increasingly

resistant to commonly used insecticides that also can be harmful

to humans and animals. Levi Littell says Venomix has overcome

those problems.

The pesticide industry has not developed or introduced “novel

agents” into the market place over the past three decades, the

company says, adding that the global market for safe and effective

insecticides is $15 billion annually. Target markets include agricul-

ture, animal health, household insects and commercial pest control.

McIntyre says the $8 million will subsidize operational costs for

the continued development of company products, as well as building

his commercial team. Venomix now employs eight people full time.

ThecompanysoonwillfileanEPARegistrationtobeginfieldtrials

nextyear.Mosquitoes,caterpillars,beetlesandflieswillbethe

unwitting targets in the trials.

Perhaps it’s serendipity but McIntyre has wound up in Michi-

gan just at a point in time when the state, academia, business and

industrybeganharnessingtheirresourcestohelpfledglingbiotech

companies, such as Venomix. McIntyre appreciates his good fortune.

“Michigan certainly has made

averysignificantstepforward

building venture capital and

facilities to attract companies

to southwest Michigan. In my

experiences over the past 20

years or longer in touring

the world, the innova-

tion center is as good

as any as I ever seen,”

he says.

SCIENTIST FINDS INSECTICIDE WEAPON INSIDE SPIDER MOUTHS

venomix iS currently developing three Spider-venom peptideS and will Sell theSe productS directly in Selected agricultural marKetS.

the “eeK!” factor of SpiderS iS loSt on John mcintyre, ph.d., for whom the inSectS are creating a web of SucceSS.



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“Michigan is on the leading edge but in an

unusual way,” says Baker, who is also director

of the Michigan Nanotechnology Institute for

Medicine and Biological Sciences, a multi-

disciplinary team of University of Michigan

scientists collaborating on nanoscience in

biology and medicine. “We certainly have a lot

of forefront research going on right now. What

we don’t have is the breadth of activity you find

on either coast. Our overall activity may be

less, but our quality is second to no one.”

An immunologist at the University of

Michigan, Baker is the executive chair of

NanoBio Corp. The nine-year-old company

develops and commercializes topical phar-

maceuticals to prevent and treat infectious

diseases, such as herpes and acne, as well as

mucosal vaccines for the flu and hepatitis B

administered through the nose.

NANOBIO LOOKS TO BIG RESULTS NanoBio is in good shape, Baker says,

pointing to “wonderful clinical data” in its

topical cold sores lotion that is as good as

any [existing] anti-viral oral drugs. “And all

you have to do is dab it on,” he says.

The company finished Phase II meetings

in April and is anticipating starting the final

pivotal trial Phase III within the next six

months, Baker says. He hopes to have the

product on the market by 2011. Baker thinks

Quality, not quantity characterizes nanomedicine research in Michigan, says Dr. James Baker Jr., who has been a world-renowned catalyst for growth in the sector.

NEW FRONTIERS

Pint-Sized nanomedicine industry Producing

Mega-Sized Results

Baker thinks that NanoBio’s lotion is so good it can domi-nate the market and be sold over the counter.


the lotion is so good it can dominate the

market and be sold over the counter. “We may

need a marketing partner, but not necessarily

a drug company,” he adds.

For its vaccines NanoBio began Phase

I clinical trials in April 2008. Commercial-

ization of a vaccine can take a little longer

because you have to follow up longer on

patients as you’re looking for an immune

response, Baker says.

AVIDIMER DEVELOPING CANCER PRODUCTS DESPITE HARD ECONOMy Avidimer Therapeutics in Ann Arbor and

NanoMed Pharmaceuticals in Kalamazoo also

are on the shortlist of outstanding nanomedi-

cine companies operating in Michigan.

Five-year-old Avidimer focuses on thera-

peutics for cancer detection and treatment. Its

polymer avidimers are designed to maximize

damage to disease targets while minimizing

collateral damage to healthy tissue and cells.

Currently its drug candidate is in the pre-

clinical stage and needs from $3 million to

$5 million to go into Phase I clinical trials.

NANOMED SEES A SOLID MARKET FOR PRODUCTS NanoMed Pharmaceuticals is a specialty

pharmaceutical company dedicated to de-

veloping therapeutic products to treat cancer

and other serious diseases. Its core technol-

ogy, Nanotemplate Engineering, is used to

formulate small molecules, peptides, proteins,

plasmid DNA, and diagnostic agents. The

company is applying its technology to refor-

mulate FDA-approved drugs to make them

more effective at treating tumors that are,

or have become, resistant to chemotherapy.

NanoMed, was founded in 2000 by

scientists Russell Mumper and Michael

Jay, inventors of its advanced drug delivery

technologies. Both men hold Ph.D.s in phar-

maceutical sciences from the University of

Kentucky, which has licensed their inventions

to NanoMed.

The scientists met Stephen Benoit at a

venture capital forum sponsored by economic

development organization, Southwest Michi-

gan First in 2001. Benoit was recruited from

Connecticut to run a Kellogg Co. division. At

the venture capital forum he liked what he

heard and saw, and he agreed to become the

company’s CEO.

The company finished its first institu-

tional funding in 2006, raising $3.3 million.

It hopes to complete a $20 million Series B

financing by year’s end, Benoit says.

NanoMed intends to self-fund early clini-

cal development and out-license products at

Phase II or later. It plans to file an IND in the

first half of 2010, with Phase I trials starting

60 to 90 days after that. The $20 million will

cover the cost of the initial trials.

Benoit says he is unfazed about raising

more money. “Oncology is an area that is still

interesting from an investor perspective.”

DENDRIMER TECHNOLOGy PAyS OFF WITH ACqUISITION Dendritic Nanotechnologies Inc. (DNT)

was started in Mt. Pleasant in 2003, built on

technology developed 30 years ago by Dow

Chemical Co.’s Donald Tomalia, who holds

a Ph.D. in chemistry. Tomalia’s technology

focused on the application of dendrimers to

safely deliver anticancer drugs, create power-

ful MRI contrast agents, and help provide

scientists innovative materials for creating

new products in numerous markets.

Today DNT is a wholly owned subsidiary

of Melbourne, Australia-based Starpharma

Holdings Ltd. Starpharma, which purchased

DNT in 2006, and develops dendrimer

nanotechnology products for pharmaceutical

applications. Ken Van Der Wende, president

and CEO of the Center for Applied Research

and Technology in Mt. Pleasant (see story on

page XX), considers its purchase by a huge

international drug company “a success story.”

Tomalia, often referred to as the father of

dendrimers, helped start Dendritech in Mid-

land, as well as a dendrimer nanotechnology

program at the University of Michigan medi-

cal school. Today he is director of the National

Dendrimer & Nanotechnology Center at

Central Michigan University.

DNT, with an investment from Starpharma,

began by manufacturing and selling a wide

variety of dendrimers to scientists. In 2005

Dow moved the dendrimers intellectual property

portfolio into DNT for a stake in the growing

nanotechnology company. That same year DNT

announced a breakthrough technology called

Priostar, a new family of dendrimers designed

to greatly reduce the cost and manufacturing

complexity associated with dendrimers.

With these and other exciting nanotech-

nologies coming out of Michigan laboratories,

expect the state’s nanoworld to expand in

coming months and years.

Avidimer’s polymer avidim-ers are designed to maximize damage to disease targets while minimizing collateral damage to healthy tissue and cells.

avidimerS are “Smart drugS” deSigned to maximize damage to diSeaSe targetS while minimizing collateral damage to healthy tiSSue.

dendrimerS can be Selected to either retain the drug throughout itS lifetime or allow it to diSaSSociate from the dendrimer following delivery.


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Balancing Life Science EffortsFor Sustainable ROI By

Linda Chamberlain, Ph.D.

Today’s headlines are filled with various uses of the term “investment”. The assorted

stimulus packages are investments in the future of our economic vitality. The re-training of

workers is an investment in sustainable skills and our ability to compete, and on and on. Given

the challenges ahead, the hypothesis of investment is one that we in the life sciences must take

particularly seriously. Perhaps in no point in history has it been so critical for our community

to deliver a return on the investments being made, and do so in a manner that is strategic and

transparent.

It seems many have come to associate life science new product development with an

“all-or-nothing” financial model – discoveries and commercialization efforts that either go

multi-platinum or die slowly in a spiral of ever-shrinking grants and dilutive equity funding.

Of course, there are no sure things. But investing in life science can and should be done in a

manner similar to a sound financial portfolio, i.e., balanced between short-, medium- and

long-term investments across diverse markets. Michigan’s investments in life science can and

should be made in a well planned fashion.

In West Michigan, the West Michigan Science & Technology Initiative (the Initiative),

has developed an inclusive strategy built around strengths in life science research and clinical

expertise, as well as legacy leadership in advanced manufacturing and human factors in

design. We are mapping a combination of life science investments, from near- term medical

device, to mid-term new diagnostic capabilities to long-term development of new therapeutics

to treat and cure disease, working diligently to maintain the investment of regional assets,

from capital to incubator space.

At the Initiative, we have a good start in implementing a balanced portfolio strategy. The

Venture Center incubator residents reflect a diversified profile: Avalon Labs in medical device,

Sequenom Center for Molecular Medicine in diagnostics, and ClinXus, Grand Valley State

University, and Michigan State University, in research for new therapeutics. These organiza-

tions have drawn over $66M in equity investment, and are promising over 500 new jobs over

the next five years.

In 2008, seeking more strategic emphasis on a shorter return, the Initiative led the forma-

tion of the West Michigan Medical Device Consortium to internationally promote existing

regional capabilities and capacities, as well as to build new, profitable collaborations. As is the

case when managing any portfolio, delivering a good return on life science investments is a

blend of science and art. Success requires collaboration and communication among many

organizations working together for a shared vision. The Initiative has built several platforms

for strategic collaborative efforts, i.e., filling gaps in product development infrastructure, and

we will continue to seek opportunities to build a comprehensive asset base from which strong,

competitive life science endeavors can be launched.

These challenging economic times place more emphasis on coordinating our state-wide

assets for strategic diversification. The time is now for leadership, planning and effective asset

management. Our many shareholders deserve nothing less.

Linda Chamberlain, Ph.D., is executive director of the West Michigan Science & Technology Initiative, based at Grand Valley State University in Grand Rapids, Michigan.


MichBio is pleased to provide the 2009 Michigan Biosciences Directory and Resource Guide, the most comprehensive listing of information on the state’s biosciences companies and organizations and the many resources they have at their disposal.

The full directory, which includes everything you see here plus company contacts, email, profiles, listings by sector and county as well as sections on Michigan’s business advantages, incentives, workforce training and more is available on CD. The CD can be purchased online at www.michbio.org for $40 including tax and shipping.

Please Note: Information contained in the 2009 Michigan Biosciences Directory and Resource Guide is as current as possible. MichBio is not responsible for any missing or incomplete data. All attempts were made to validate information submitted by companies and update existing data in MichBio’s archives. Companies and organizations bear sole responsibility for their profiles.

Add your Company or Make CorrectionsIf your bioscience company, related organization or institution is not listed in this directory, and you believe it should be OR if your listing requires corrections, please contact MichBio at [email protected] or (734) 527-9150.

2009 DIRECTORy and RESOURCE GUIDE

BioMattersM A y 2 0 0 9

MichiganBiosciences


Small Business association of Michigan

helps Michigan small businesses succeed by

promoting entrepreneurship, leveraging buy-

ing power and engaging in political advocacy.

www.sbam.org

(800) 362-5461

CENTERS FOR ExCELLENCEBiosciences research and Commer-cialization Center of Western Michigan

University is a commercially focused and sci-

ence driven translational research center that

dedicates its pharmaceutical expertise and

resources to the commercialization of promis-

ing bioscience discoveries and the growth of

Michigan’s bio-science business sector.

www.brcc.wmich.edu

(269) 544-1072

Grand river aseptic Pharmaceutical Packaging is a fully validated, FDA/cGMP

facility associated with the VAI and Grand

Valley State University (GVSU) and serves

the bio/pharmaceutical industry by offering

aseptic fill-finish, lyophilization, client-driven

custom packaging services and cold product

storage.

www.grandriverapp.com

(616) 644-0555

Michigan animal Models Consortium (MaMC) provides services associated with

the development, analysis and maintenance

of mouse models of human disease. The

consortium combines the technological,

IP expertise and facility resources at the

AAALAC-accredited Van Andel Institute

(VAI). The MAMC provides efficient and

cost-effective animal modeling services.

www.ctaalliance.org/cta-cores/michigan-

animal-model-consortium

(616) 234-5684

overall business climate. It can link you with

all the state has to offer and guide you to the

wide array of economic development tools

that make Michigan the best choice for your

company.

www.michiganadvantage.org

(888) 522-0103

Michigan Innovation equipment Depot

facilitates growth of biosciences companies

throughout Michigan with access to previ-

ously used laboratory equipment critical to

product research, development and manu-

facturing. It is the result of the collaborative

efforts of Pfizer, MichBio, Ann Arbor SPARK,

Southwest Michigan First and other Michigan

SmartZonesTM to accelerate the commercial-

ization of biotechnologies.

www.michbio.org

(734) 527-9150

Michigan Small Business & technology Development Center (SBtDC) provides

counseling, training, research and advocacy

for new ventures, existing small businesses

and innovative technology companies. Head-

quartered at Grand Valley State University,

the SBTDC supports 12 regional offices and

over 30 satellite offices in the state through

a cooperative agreement with the U.S. Small

Business Administration.

www.gvsu.edu/misbtdc

(616) 331-7480

New enterprise Forum links entrepreneurs

with management expertise, joint venture

partners, business services, capital, and other

critical resources.

www.newenterpriseforum.org

(734) 665-4433

GENERAL RESOURCESMichBio is the statewide association committed

to building Michigan’s biosciences industry into

a growth engine for a revitalized economy. Its

members are biosciences companies, academic

and research institutions, bioscience service

providers, and related organizations. MichBio

is dedicated to fostering their collective impact

by connecting its members with the essential

resources, including goods, services, educational

and networking programs, legislative representa-

tion, and partners that facilitate success.

www.michbio.org

(734) 527-9150

BioConnections is a program for MichBio

members matching talented life sciences pro-

fessionals with fulfilling positions in the state

through an online talent search mechanism.

www.michbio.org/BioConnections

(734) 527-9150

Great Lakes entrepreneur’s Quest (GLeQ) helps Michigan entrepreneurs build high-

growth, new economy business ideas into suc-

cessful ventures by linking them to a statewide

network of resources, expert advice, educa-

tion and capital. Twice a year, GLEQ hosts a

statewide business plan competition with cash

prizes, media exposure and business develop-

ment services.

www.gleq.org

(734) 527-9151

Michigan economic Development Corpo-ration (MeDC) is the state’s one-stop resource

for businesses seeking to grow in Michigan.

Created through cooperation between state and

local governments, the MEDC works with local

communities and businesses to retain and ex-

pand job opportunities and improve Michigan’s

Abundant Resources Help Ideas Become

Life-Changing Realities


Michigan antibody technologies Center (MatC) consists of the Monoclonal

Antibody Technology Core at the VAI and

the Hybridoma Core at the University of

Michigan (U-M). The MATC has extensive

capabilities in the generation, characteriza-

tion, scale-up and purification of mAbs and

fragments.

www.vai.org/Research/Labs/AntibodyTech-

nology.aspx

(616) 234-5342

Michigan Biological Imaging Center (MBIC) provides comprehensive scientific/

technical imaging expertise including drug

safety and efficacy data to pharmaceutical

industry clients.

homepages.wmich.edu/~eversole

(269) 387-5640

Michigan Center for Biological Infor-mation (MCBI) provides advanced bio-

informatics and computational resources

for investigators and in the academic and

industrial sectors. This includes access to

bioinformatics tools, genomics and proteomics

databases, supercomputing resources, bioinfor-

matics training, and bioinformatics consulting.

www.ctaalliance.org/MCBI

(734) 615-5814

Michigan Center for Bioscience Commercialization (MCBC) is a contract

research and development organization

located at the BRCC. The MCBC provides

scientific, medical and regulatory consulta-

tion to aid in the development and commer-

cialization of pharmaceutical, diagnostic

and medical device discoveries.

www.brcc.wmich.edu

(269) 544-1072

Michigan Center for Structural Biology (MCSB) is designed to provide state-of-the-

art instrumentation and support in the area

of macro-molecular structure/function de-

termination for drug discovery. This includes

x-ray crystallography, NMR spectroscopy,

EPR spectroscopy, single molecular spectros-

copy, protein expression and production and

macromolecular structure, synthesis and

sequencing. The MCSB is partnered with and

utilizes beamline resources at the Argonne

National Labs.

mcsb.bch.msu.edu

(517) 355-0199

Michigan High-Throughput Screening Center (MHtSC) is a contract research

facility providing services in assay develop-

ment and optimization and high throughput

screening. Staffed by pharmaceutical industry

scientists with drug discovery and HTS

experience, the MHTSC offers screening of

a 100,000+ compound library for a broad

range of therapeutic targets with the client

retaining IP rights to compounds identified in

the screenings.

www.mhtsc.kvcc.edu

(269) 353-1582

Michigan Proteome Consortium (MPC)

provides proteome mapping (protein interac-

tion maps, membrane protein analysis, post-

translational modifications), high-throughput

yeast two-hybrid screening, and proteome

informatics services to both academic and

industry clients.

www.proteomeconsortium.org

(734) 763-3130

Wayne State university applied Ge-nomic technologies (MCGt) provides

oligonucleotide genechip microarrays, custom

cDNA microarrays, and other genomic tech-

nology services on a fee-basis. State-of-the-

art equipment and a full suite of molecular

genomic tools for processing and analysis

means an integrated offering for gene

expression profiling and HTS data mining.

www.bioinformatics.wayne.edu/MCGT

(313) 577-3555

MiChigAn-BASEd FUnding SOURCESThe 21st Century Jobs Fund represents

a bold initiative to diversify Michigan’s

economy and stimulate job creation in

emerging technology sectors. After being

introduced by the Governor in 2005, it re-

ceived broad, bi-partisan support in the state

Legislature. Using tobacco settlement dollars,

it has already invested $156 million in over

95 commercialization projects in the life

sciences, advanced manufacturing, alterna-

tive energy, and homeland security/defense

sectors through business plan competitions.

In addition, the 21st Century Jobs Investment

Fund was deployed to invest $109 million

in venture capital and private equity funds.

To date nearly $75 million has been invested

and attracted significant fund management

activity to Michigan, providing Michigan

entrepreneurs access to more diverse capital.

www.michiganadvantage.org/21

Michigan Initiative for Innovation and entrepreneurshipThe Michigan Initiative for Innovation &

Entrepreneurship (MIIE) builds on

Michigan’s universities as economic assets

by speeding the commercialization of

university research while promoting a culture

of entrepreneurial risk-taking. The initiative

partners Michigan’s philanthropic resources

with university and private business resources

to help launch new startup companies, and

strengthen ties between small business,

industry and academia.

www.pcsum.org/miie.html

(734) 647-5730

Michigan Pre-Seed Capital Fund

supports high-tech start-up companies as

they near commercial viability by providing

access to early-stage capital to accelerate

company development. These funds extend

the personal investment of entrepreneurs

during the critical stage when they are

developing their businesses to the point of

readiness for outside investment. Information

is available from local SmartZonesTM or

www.AnnArborUSA.org

Venture Michigan Fund is a $95 million

venture capital investment program formed

under the Michigan Early Stage Venture

Investment Act of 2003 to promote Michigan’s

economic health by assisting in the creation

of jobs, new businesses and new industries

D I R E C TO Ry & R E S O U R C E G U I D E


within the state. The VMF makes investments

ONLY in venture firms that invest primarily

in Michigan-based early stage companies.

www.venturemichigan.com

Federal Funding Opportunities are listed

in the SSTI Weekly Funding Supplement

offered by the federal government, founda-

tions and other industries.

www.ssti.org/Digest/supplement.htm

VENTURE AND ANGEL GROUPSann arbor angels www.annarborangels.org

apjohn Group, LLC www.apjohnventures.com

arbor Partners www.arborpartners.com

arboretum Ventures www.arboretumvc.com

ardesta, LLC www.ardesta.com

Beringea www.beringea.com

BioStar Ventures www.biostarfund.com

Bridge Street Capital www.bridgestreetcapital.com

Capital Community angels www.capitalcommunityangels.org

Capital Strategies Group www.capitalstrategiesgroup.com

Detroit Community Loan Fund www.detroitrenaissance.com

Dow Venture Capital www.dow.com/venture

eDF Ventures www.edfvc.com

entrepreneurs and Investors exchange www.EntrepreneurInvestorExchange.com

First angels www.swmfirst.com/First_Angels.cfm

Fletcher Spaght Ventures www.fletcherspaght.com/ventures

Grand angels www.grandangels.org

Great Lakes angels www.glangels.org

Great Lakes entrepreneur’s Quest www.gleq.org

Hartwick Capital www.hartwickcapital.com

MacBeedon Partners LLC www.macbeedon.com

Michigan Venture Capital association www.michiganvca.org

North Coast technology Investors www.northcoastvc.com

renaissance Venture Capital Fund www.renvcf.com

Seneca Partners www.senecapartners.com

Sigvion Capital www.sigvion.com

Southwest Michigan First Life Science Fund www.southwestmichiganfirst.com

tGap Ventures www.tgapventures.com

Wolverine Venture Fund www.zli.bus.umich.edu/wvf

UNIVERSITy RESEARCH AND TECHNOLOGy TRANSFERMichigan universities Commercializa-tion Initiative (MuCI) complements and

enhances technology transfer functions at

Michigan academic and research institutions

by supporting commercialization of Intel-

lectual Property.

www.muci.org

technology transfer Offices: l Central Michigan university www.orsp.cmich.edu

(989) 774-4000

l eastern Michigan university www.ord.emich.edu

(734) 487-3090

l Ferris State university www.ferris.edu

(231) 591-5983

l Grand Valley State university www.gvsu.edu/research_dev

(616) 331-2281

l Michigan State university http://www.oip.msu.edu/

(517) 355-2186

l Michigan technical university www.admin.mtu.edu/adv/cs/

(906) 487-2228

l Northern Michigan university webb.nmu.edu/Departments/TOS

(906) 227-2190

l Oakland university www2.oakland.edu/research

(248) 370-2552

l Saginaw Valley State university http://www.svsu.edu/cbed

(989) 964-4047

l university of Michigan www.techtransfer.umich.edu

(734) 763-0614

l Van andel research Institute www.vai.org

(616) 234-5000

l Wayne State university www.techtransfer.wayne.edu

(313) 577-5541

l Western Michigan university www. www.brcc.wmich.edu

(269) 544-1072 university research Corridor is an alli-

ance between Michigan’s three major research

universities to transform, strengthen and

diversify the state’s economy. The partners,

Michigan State University, the University of

Michigan and Wayne State University, spark

regional economic development via inven-

tion, innovation and technology transfer,

by educating a work force prepared for the

knowledge economy, and by attracting smart

and talented people to Michigan.

www.urcmich.org



SMARTZONES AND BUSINESS ACCELERATORS SmartZonestM provide distinct geographi-

cal locations where technology-based firms,

entrepreneurs and researchers locate in close

proximity to all of the community assets that

assist in their endeavors. SmartZoneTM tech-

nology clusters promote resource collabora-

tions between universities, industry, research

organizations, government and other

community institutions, growing technology-

based businesses and jobs. New and emerging

businesses in SmartZoneTM technology

clusters are primarily focused on commercial-

izing ideas, patents and other opportunities

surrounding corporate, university or private

research institute R&D efforts.

www.michigan.org/smartzones

l ann arbor/ypsilanti: Ann Arbor SPARK,

University of Michigan,

Eastern Michigan University

201 S. Division St., Suite 430

Ann Arbor, MI 48104

(734) 761-9317

www.AnnArborUSA.org

Contact: Michael Finney

l automation alley Lawrence Institute of Technology,

Oakland University

Automation Alley Technology Center

2675 Bellingham Rd

Troy, MI 48083

(248) 457-3200

www.automationalley.com

Contact: Tom Anderson

l Battle Creek aviation & e-Learning Western Michigan University,

Kellogg Community College

4950 West Dickman Rd.

Battle Creek, MI 49037

(269) 962-7526

www.bcunlimited.org

Contact: Karl Dehn

l Detroit/Woodward technology Corridor: techtown Wayne State University

440 Burroughs, Entrepreneurial Suite

Detroit, MI 48202

(313) 879-5250

www.techtownwsu.org

Contact: Randal Charlton

l Grand rapids: West Michigan Science & technology Initiative Grand Valley State University,

Van Andel Institute

301 Michigan St NE, Suite 536

Grand Rapids, MI 49503

(616) 331-5840

www.wmsti.org

Contact: Linda Chamberlain

l Houghton/Hancock: Michigan tech enterprise Corporation Michigan Technical University

Advance Technology Development

Complex

101 West Lakeshore Drive

Houghton, MI 49931

(906) 487-7000

www.mtecsmart.com

Contact: Carlton K. Crothers

l Jackson technology Park Baker College, Jackson Community

College, Spring Arbor University

3925 County Farm Road

Jackson, MI 49201

(517) 788-4455

www.enterprisegroup.org

Contact: Scott Fleming

l Kalamazoo: WMu Business technology & research Park Western Michigan University

4717 Campus Drive, #100

Kalamazoo, MI 49008

(269) 353-1823

www.kazoosmic.com

Contact: Robert DeWit

l Lansing/east Lansing: university Corporate research Park 2727 Alliance Drive, Ste. C

Lansing, MI 48910

(517) 432-1753

ucrp.msu.edu

Contact: George Benson

l Macomb technology advancement Oakland University

6555 15 Mile Road

Sterling Heights, MI 48312

(586) 463-2542

www4.oakland.edu/?id=6871&sid=213

Contact: Luke Bonner

l Midland: Mt. Pleasant SmartZonetM Satellite MidMichigan Innovation Center

4520 E. Ashman Rd., Suite M

Midland, MI 48642

(989) 839-2333

www.midmichiganinnovationcenter.org

Contact: Brent Case

l Mt. Pleasant: Center for applied research & technology Central Michigan University

2625 Denison Drive

Mt. Pleasant, MI 48858

(989) 774-2424

www.cmurc.com

Contact: Ken Van Der Wende

l Muskegon Lakeshore Grand Valley State University

380 W. Western Ave, Suite 202

Muskegon, MI 49440

(231) 724-6702

www.muskegonareafirst.org

Contact: Ed Garner

lrochester Hills: Oakland university INCubator Oakland University Shotwell-Gustafson

Pavilion, Oakland University

2200 N. Squirrel Road

Rochester, MI 48309

(248) 648-4800

www.oakland.edu/ouinc

Contact: David Spencer



l Sault St. Marie Economic Development Corp.

1301 West Easterday Ave.

Sault Ste. Marie, MI 49783

(906) 635-9131

www.saultedc.com

Contact: Jim Hendricks

l Wayne County: Pinnacle aeropark University of Michigan, Wayne State

University, Detroit Metropolitan Airport

600 Randolph Street, Third Floor

Detroit, MI 48226

(313) 224-6076

www.waynecounty.com

Contact: Dave Tyler

SELECTED MICHIGAN COUNTy ECONOMIC DEVELOPMENT ORGANIZATIONSalcona

ww.alconacountymi.com

allegon www.allegancounty.org

Bay

www.baycounty-mi.gov/EACD/EconomicDe-

velopment.aspx

Benzie

www.benziecountyedc.com

Berrien

www.berriencounty.org

Calhoun

www.calhouncountymi.org

Genesee

www.thegrcc.org

Houghton

www.houghtoncounty.net

Ingham

www.ingham.org/DV/developm.htm

Ionia

www.icea-mi.org

Isabella

www.mmdc.org

Jackson

www.co.jackson.mi.us/JCinfo.asp

Kalamazoo

www.southwestmichiganfirst.com

Kent www.rightplace.org

Leelanau

www.leelanaucounty.com/edc.asp

Lenawee www.lenawee.mi.us

Livingston

www.livingstonedc.com

Manistee

www.allianceforeconomicsuccess.com

Marquette

www.marquette.org/economic_main.html

Macomb

www.macombcountymi.gov/MCPED

Mason

www.masoncountyedc.com

Midland

www.midlandtomorrow.org

Monroe www.monroecountyidc.com

Muskegon

www.muskegonareafirst.org

Newaygo

www.ncedo.org

Oakland

www.oakgov.com/peds

Ontonagon

www.ontcoedc.com

Otsego

www.otsego.org/econdev.htm

Ottawa www.co.ottawa.mi.us

Saginaw

www.saginawfuture.com

Sanilac

www.sanilaccounty.org

Schoolcraft www.schoolcraftedc.com

St. Clair

www.edascc.com

St. Joseph www.sjcedc.com

traverse Bay www.tcchamber.org

Van Buren www.vbco.org/econdev0003.asp

Washtenaw

www.AnnArborUSA.org

Wayne

www.waynecounty.com/jed

For a complete list of Michigan economic

development organizations, please visit

www.ecodevdirectory.com/Michigan.htm




Advanced X-Ray Technology, inc.1025 East Maple Road, Suite 210 Birmingham, MI 48009 (248) 901-0525 www.axt-medical.com Medical Devices

Advantage Capital Partners 7733 Forsyth Boulevard, Suite 1850 St. Louis, MO 63015 www.advantagecap.com Venture Capital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

AEGIS Environments 2205 Ridgewood Drive Midland, MI 48642 (800) 241-9186 www.microbeshield.com Industrial & Environmental, Medical Devices, Contract R&D

AFID Therapeutics Inc. 3900 Collins Road, Suite 1029 Lansing, MI 48910 (517) 336-4641 www.afidtherapeutics.com Pharmaceutical & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Agfa Corporationwww.agfa.com/usa/en/he/index.jsp Medical Devices, Informatics

Agrium 2405 Vassar Road Reese, MI 48757 (989) 752-2138 www.agrium.com Agriculture & Food

AI Medical Devices, Inc. 311 Turner Road Williamston, MI 48895 (517) 881-8804 www.aimedicaldevices.com Medical Devices

Air Force Inc. 933 Butternut Drive Holland, MI 49424 (616) 399-8511 www.dentalairforce.com Medical Devices

AIS Consulting 4343 Concourse Drive, Suite 220 Ann Arbor, MI 48108 (734) 769-7470 www.aisconsulting.biz Contract R&D, Informatics

21st Century Therapeutics, Inc.52673 Seven Oaks, Suite 105 Shelby Township, MI 48316 (313) 874-4879 Pharmaceutical & Therapeutics

3D Biomatrix 401 West Morgan Ann Arbor, MI 48108 (734) 945-8131 Research Tools

A

AAPharmaSyn LLC 3985 Research Park Drive Ann Arbor, MI 48108 (734) 213-2123 www.aapharmasyn.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Aastrom Biosciences, Inc.24 Frank Lloyd Wright Drive, Lobby K Ann Arbor, MI 48105 (734) 930-5555 www.aastrom.com Pharmaceutical & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Abbott Nutrition 901 North Centerville Road Sturgis, MI 49091 (269) 651-0787 www.abbott.com Pharmaceutical & Therapeutics

Absolute Analytical, Inc.240 West Auburn Road Rochester Hills, MI 48307 (248) 844-2800 Contract R&D, Industrial & Environmental

Access Business Group7575 Fulton Street East Ada, MI 49355 (616) 787-6767 www.accessbusinessgroup.com Contract R&D

Accord Biomaterials, Inc.3550 West Liberty Road, Suite 3 Ann Arbor, MI 48103 (734) 995-9089 www.accordbiomaterials.com Medical Devices • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Accumed Systems Inc.6109 Jackson Ann Arbor, MI 48103 (734) 930-0461 www.accumedsystemsinc.com Medical Devices

Accuri Cytometers 173 Parkland Plaza Ann Arbor, MI 48103 (734) 994-8000 www.AccuriCytometers.com Research Tools • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Acuity Medical, Inc. 10524 Grand River Brighton, MI 48116 (810) 229-5828 www.acuitymedical.com Medical Devices

Adamlab, LLC 55 East Long Lake Road, Suite 337 Troy, MI 48085 (248) 362-9603 www.adamlab.com Medical Devices

Adeona Pharmaceuticals 3930 Varsity Drive Ann Arbor, MI 48108 (734) 332-7800 www.adeonapharma.com Pharmaceutical & Therapeutics

ADMETRx 4717 Campus Drive Kalamazoo, MI 49008 (269) 372-3272 www.admetrx.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Advanced Photonix Inc. 2925 Boardwalk Ann Arbor, MI 48104 (734) 864-5639 www.advancedphotonix.com Medical Devices, Research Tools

Advanced Sensor Technologies, Inc.300 River Place, Suite 6850 Detroit, MI 48207 (248) 553-9375 www.advsensortech.com Medical Devices



AP Bio-Consulting llC40799 Coachwood Circle Northville, MI 48168 (413) 451-8225 www.apbioconsulting.com Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Apjohn Group, LLC350 East Michigan Avenue, Suite 500 Kalamazoo, MI 49007 (269) 349-8999 www.apjohngroup.com Venture Capital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

ApoLife, Inc.100 River Place, #6800 Detroit, MI 48207 (313) 446-2625 www.apolife.com Research Tools, Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Aptuit Consulting, Inc91 Hartwell Avenue Lexington, MA 02421 (781) 778-0418 www.aptuitconsulting.com Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

AquaBiochip, LLC1012 North Walnut Street, Suite 101 Lansing, MI 48906 (517) 402-2692 www.aquabiochip.com Contract R&D, Diagnostics

Arbor Preclinical & Consulting, LLC(734) 330-4396 www.arborpcc.com Contract R&D

Arbor Research Collaborative for Health 315 West Huron Street, Suite 360 Ann Arbor, MI 48103 (734) 665-4108 www.arborresearch.org Contract R&D, Informatics

Akervall Technologies 5520 Stonevalley Drive Ann Arbor, MI 48105 (734) 485-2949 Medical Devices

Albemarle Corporation 1421 South Kalamazoo Street South Haven, MI 49090 (269) 637-8474 www.albemarle.com Contract R&D

Alivio Corporation 20429 Honor Highway Interlochen, MI 49643 (231) 275-1345 www.aliviocorp.com Medical Devices

Alluvium Biosciences Inc. 789 N. Dixboro Road Ann Arbor, MI 48105 (734) 276-4921 Contract R&D, Industrial & Environmental, Pharmaceuticals & Therapeutics

AlphaCore Pharma 2900 Huron Parkway, Suite 5 Ann Arbor, MI 48105 (734) 330-0265 Pharmaceutical & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

SILVER SPONSOR

Altarum Institute 3520 Green Court, Suite 300 P.O. Box 134001 Ann Arbor, MI 48105 (734) 302-4600 www.altarum.org University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

American Dental Technologies, Inc.28265 Beck Road, Suite C-22 Wixom, MI 48393 (800) 359-1959 www.americandentaltech.com Medical Devices

American Diabetes Association30300 Telegraph Road, Suite 117 Bingham Farms, MI 48025 (248) 433-3830 www.diabetes.org Association/Non-profit

American Society for Microbiology9205 Huron River Drive Dexter Township, MI 48130 (734) 845-3661 www.mi-asm.org Association/Non-profit

American Society of Employers23815 Northwestern Highway Southfield, MI 48075 (248) 353-4500 www.aseonline.org Association/Non-profit • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Amgen 9935 North Valley Hill Drive Mequon, WI 53092 (262) 240-9961 www.amgen.com Pharmaceutical & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Amigo Mobility International 6693 Dixie Highway Bridgeport, MI 48722 (989) 921-5062 www.myamigo.com Medical Devices

Angott Medical Products, LLC 442 Five Gaits Court Bloomfield Hills, MI 48304 (248) 444-1492 Medical Devices

Ann Arbor Clinical Research203 South Zeeb Road, Suite 105 Ann Arbor, MI 48103 (734) 926-0957 www.annarborclinicalresearch.com Contract R&D

Ann Arbor SPARK201 South Division, Suite 430 Ann Arbor, MI 48104 (734) 761-9317 www.AnnArborUSA.org Government/Economic Development • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Antel BioSystems, Inc 3655 Forest Road Lansing, MI 48910 (800) 631-3510 www.antelbio.com Contract R&D, Diagnostics



Automation Alley2675 Bellingham Troy, MI 48083 (248) 457-3200 www.automationalley.com Government/Econ Dev. • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

AVAcore Technologies 333 Parkland Plaza Drive, Suite 700 Ann Arbor, MI 48103 (888) 282-2673 www.avacore.com Medical Devices

Avalon Laboratories LLC301 Michigan Street, Suite 500 Grand Rapids, MI 49503 (616) 331-5843 www.avalonlabs.com Medical Devices, Contract R&D

Avicenna Medical Systems, Inc.3090 Dhu Varren Court Ann Arbor, MI 48105 (888) 284-4080 www.avicenna-medical.com Informatics

Avidimer Therapeutics, Inc.P.O. Box 7735 Ann Arbor, MI 48107 (866) 229-1387 www.avidimer.com Pharmaceutical & Therapeutics

Axenic Dental, Inc.259 East Michigan Avenue, Suite 409 Kalamazoo, MI 49007 (269) 349-8870 Medical Devices

Axsys Technologies, Inc.2909 Waterview Drive Rochester Hills, MI 48309 (248) 293-2900 www.axsys.com Medical Devices

AzoRx, Inc.526 Jasper Street Kalamazoo, MI 49007 (269) 585-5953 www.azorx.com Contract R&D

Arboretum Ventures334 East Washington Street Ann Arbor, MI 48104 (734) 998-3688 www.arboretumvc.com Venture Capital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Ardesta, LLC201 South Main Street, 10th Floor Ann Arbor, MI 48104 (734) 994-7000 www.ardesta.com Venture Capital

Arivium, Inc.354 Glen Arbor Drive NE Rockford, MI 49341 (616) 292-5018 www.arivium.com IT Services & Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Armune BioScience, Inc.350 East Michigan Avenue, Suite 500 Kalamazoo, MI 49007 (269) 349-8870 www.armune.com Diagnostics

PATRON

Ash Stevens5861 John C. Lodge Freeway Detroit, MI 48202 (313) 872-6400 www.ashstevens.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

ASI Instruments, Inc.12900 East Ten Mile Road Warren, MI 48089 (586) 756-1222 www.asi-instruments.com Medical Devices, Research Tools

Aspen Surgical Products, Inc.6945 Southbelt Drive SE Caledonia, MI 49316 (616) 698-7100 www.aspensurgical.com Medical Devices, Research Tools

Assay Designs, Inc.5777 Hines Drive Ann Arbor, MI 48108 (734) 668-6113 www.assaydesigns.com Research Tools, Diagnostics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

BRONZE SPONSOR

Asterand, Inc.TechOne Building, 440 Burroughs, Suite 501 Detroit, MI 48202 (313) 263-0960 www.asterand.com Research Tools, Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

ATEK Medical Manufacturing620 Watson SW Grand Rapids, MI 49504 (616) 643-5200 www.atekcompanies.com Contract R&D, Medical Devices

Ateq Corporation42000 Koppernick Road Canton, MI 48187 (734) 451-9449 www.atequsa.com Medical Devices

Atodyne Technologies LLC4699 Pontiac Trail Ann Arbor, MI 48105 (734) 761-5282 www.atodyne.com Medical Devices

AureoGen Biosciences, Inc.6475 Technology Avenue, Suite C Kalamazoo, MI 49009 (269) 353-3805 www.aureogen.com Pharmaceutical & Therapeutics

Aursos, Inc.350 East Michigan Avenue, Suite 500 Kalamazoo, MI 49007 (269) 381-4408 www.aursos.com Pharmaceutical & Therapeutics

Autocam Corporation4436 Broadmore SE Kentwood, MI 49512 (800) 747-6978 www.autocam.com Medical Devices



Biodiscovery, LLC5992 Plymouth Road Ann Arbor, MI 48105 (734) 998-0751 www.Mycroarray.com Research Tools, Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

BioFlow Technology, Inc11477 North Shore Drive Whitmore Lake, MI 48189 (734) 223-1946 www.bioflowtech.com Research Tools, Medical Devices

Bio-lab, inc., A Chemtura Company 1400 East Michigan Street Adrian, MI 49221 (517) 265-6138 www.chemtura.com Industrial & Environmental

BioLumix, Inc 3830 Packard Road, Suite 180 Ann Arbor, MI 48108 (734) 973-5870 www.mybiolumix.com Research Tools, Medical Devices

Biomedical Diagnostics, LLC5692 Plymouth Road, Suite B Ann Arbor, MI 48105 (734) 913-9040 www.bio-diagnostics.com Diagnostics

BioMedPharmIS, Ltd. 350 East Michigan Avenue, Suite 410 Kalamazoo, MI 49007 (269) 488-3301 www.biomedpharmis.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

BioMedware Inc.516 North State Street Ann Arbor, MI 48104 (734) 913-1098 www.biomedware.com Informatics

Biomide21 Kercheval Avenue, Suite 330 Grosse Pointe Farms, MI 48236 (313) 886-0589 Pharmaceuticals & Therapeutics

B

Bank of Ann Arbor125 South Fifth Avenue P.O. Box 8009 Ann Arbor, MI 48104 (734) 662-1600 www.boaa.com Banking • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Bauer BioMedical, LLC2526 Denison Drive Mt. Pleasant, MI 48854 (810) 397-2882 Diagnostics

Bayer CropScience1740 North Whitehall Muskegon, MI 49445 (231) 719-3000 www.bayercropscience.com Agriculture & Food

Bayer HealthCare6549 Braemar Avenue Noblesville, IN 46069 (317) 774-8069 www.bayerhealth.com Pharmaceutical & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Beaumont Commercialization Center3601 West Thirteen Mile Road Royal Oak, MI 48073 (248) 551-0255 www.beaumontcommercializationcenter.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

BRONZE SPONSOR

Beaumont Hospitals3601 West Thirteen Mile Road Royal Oak, MI 48073 (248) 551-8550 www.beaumonthospitals.com University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Beaumont Services Company LLC3601 West Thirteen Mile Road Royal Oak, MI 48073 (248) 551-3010 www.beaumontservices.com Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Becker Orthopedic635 Executive Drive Troy, MI 48083 (248) 588-7480 www.beckerorthopedic.com Medical Devices

Becton dickinson - difco Laboratories920 Henry Street Detroit, MI 48201 (313) 442-8800 www.bd.com Research Tools, Diagnostics

Berry & Associates, Inc.2434 Bishop Circle East Dexter, MI 48130 (734) 426-3787 www.berryassoc.com Research Tools

Better Rehab, LLC1170 Morehead Court Ann Arbor, MI 48104 (734) 604-1966 Informatics

Bio Logic Engineering, Inc.1675 N. Lima Center Road Dexter, MI 48130 (734) 433-9256 www.biologicengineering.com Medical Devices

Bio-Chem laboratories, inc.1049 28th Street, SE Grand Rapids, MI 49508 (616) 248-4900 www.bio-chem.com/Home/tabid/36/Default.aspx Contract R&D

Bio-Coat inc.21249 Bridge Street Southfield, MI 48034 (248) 352-4570 Medical Devices



Borgess Research Institute 1521 Gull Road Kalamazoo, MI 49048 (269) 226-5407 www.research.borgess.com University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

BoroPharm, Inc. 39555 Orchard Hill Place Novi, MI 48375 (888) 366-1496 www.boropharm.com Contract R&D

Bremer Prosthetics, Inc. G3487 South Lindin Road, Suite U Flint, MI 48507 (810) 733-3375 www.bremerprosthetics.com Medical Devices

Brenner Orthotic and Prosthetic Labs 32975 West Eight Mile Road Livonia, MI 48152 (810) 615-0601 Medical Devices

Bridge Organics Co. 311 West Washington Street Vicksburg, MI 49097 (616) 649-4200 www.bridgeorganics.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Brinks, Hofer, Gilson & Lione 524 S. Main Street, Suite 200 Ann Arbor, MI 48104 (734) 994-6285 www.brinkshofer.com Attorneys • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Brooks Kushman 1000 Town Center, Suite 2200 Southfield, MI 48075 (248) 358-4400 ext. 2770 www.brookskushman.com Attorneys • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Bio-nano Power llC2625 Denison Dr. Mt. Pleasant, MI 48858 (616) 682-0367 Medical Devices

BioPharma Data Services1461 Scio Ridge Ct Ann Arbor, MI 48103 (734) 255-1038 www.BioPharmaDataServices.com Contract R&D, Informatics

Biophotonic Solutions, Inc.3590 Breezy Point Drive Okemos, MI 48864 (517) 881-4562 www.biophotonicsolutions.com Research Tools, Medical Devices

Biopolymer Innovations16647 Chandler Road East Lansing, MI 48823 (517) 432-3044 www.biopolymerinnovations.com Pharmaceutical & Therapeutics, Industrial & Environmental

BioPro 17 17th Street Port Huron, MI 48060 (810) 982-7777 www.bioproimplants.com Medical Devices

Biosciences Research &Commercialization Center - Center for Technology Excellence 4717 Parkview Campus Drive Kalamazoo, MI 49008 (269) 544-1072 www.brcc.wmich.edu University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Biosol, Ltd.206 South Fifth Avenue, Suite 500 Ann Arbor, MI 48104 (313) 994-5300 www.liposol.com Research Tools

BioSTAT Consultants, Inc. 528 West Centre Avenue Portage, MI 49024 (269) 329-7976 www.biostat.net Contract R&D

Biotech Clinical Laboratories 24469 Indoplex Circle Farmington Hills, MI 48335 (248) 426-9800 www.biotechclinical.com Contract R&D, Diagnostics

SUPPORTER

Biotechnology Business Consultants (BBC) 803 North Main Street Ann Arbor, MI 48104 (734) 930-9741 www.bioconsultants.com Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Biotectix 2900 Huron Parkway Ann Arbor, MI 48104 (781) 353-6404 www.biotectix.com Diagnostics, Research Tools, Industrial & Environmental • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Biotronic Neural Monitoring Specialists 812 Avis Drive Ann Arbor, MI 48108 (866) 856-4404 www.biotronic.com Medical Devices

Birchbrook Technologies LLC53470 Andrew Circle New Baltimore, MI 48047 (586) 648-8267 www.birchtek.com Medical Devices

Bluestone Realty Advisors 325 East Eisenhower, Suite 308 Ann Arbor, MI 48108 (734) 665-6500 www.blueadvisors.com Real Estate • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

BlueWare, Inc. 3060 West 13th Street Cadillac, MI 49601 (231) 779-0224 www.blueware.net Informatics, Contract R&D



Cayman Chemical Company1180 East Ellsworth Road Ann Arbor, MI 48108 (734) 971-3335 www.caymanchem.com Research Tools, Diagnostics

CeeTox, Inc.4717 Campus Drive Kalamazoo, MI 49008 (269) 353-5555 www.ceetox.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Cell Culture Characterization Services 1872 North Adams Rochester Hills, MI 48306 (248) 656-2542 Contract R&D, Diagnostics

Central Michigan University -Office of Research and Sponsored Programs 251 Foust Hall Mt. Pleasant, MI 48859 (989) 774-6777 www.orsp.cmich.edu University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Central Michigan University -Research Corporation 2625 Denison Drive Mt. Pleasant, MI 48858 (989) 774-2424 www.cmurc.com University/Institutions/Hospitals • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Centromine, Inc.3756 Plaza Drive Ann Arbor, MI 48108 (734) 352-0020 www.centromine.com Informatics

Cerenis Therapeutics Inc.900 Victors Way, Suite 280 Ann Arbor, MI 48108 (734) 769-1110 www.cerenis.com Pharmaceutical & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Brown & Brown of Detroit 305 East Eisenhower Parkway, Suite 100 Ann Arbor, MI 48108 (734) 995-4444 ext. 3781 www.alcos.com Insurance Provider • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Bruce Johnson Service Co. Inc.4363 South Old US Hwy 23 Brighton, MI 48114 (810) 227-5130 www.BruceJohnsonService.com Lab Equipment • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Burdick & Jackson 1953 South Harvey Street Muskegon, MI 49442 (231) 726-3171 www.bandj.com Industrial & Environmental, Agriculture & Food

Butzel Long 350 South Main Street, Suite 300 Ann Arbor, MI 48104 (734) 213-3435 www.butzel.com Attorneys • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

C

Caladium Consulting 1682 Baker Road Dexter, MI 48130 (734) 476-5232 www.caladiumconsulting.com Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Calibrate, inc. - The Pipet People3600 Green Court, Ste. 400 Ann Arbor, MI 48105 (919) 929-3004 www.pipetpeople.com Lab Equipment • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Caltech Industries, Inc.4520 East Ashman Road, Suite C Midland, MI 48642 (989) 496-3110 www.caltechind.com Industrial & Environmental, Agriculture & Food

Canadian Consulate General600 Renaissance Center, Suite 1100 Detroit, MI 48243 (313) 446-7016 www.detroit.gc.ca Government/Econ Dev. • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Capital Advisors Group, Inc.29 Crafts Street, Ste. 270 Newton, MA 02458 (617) 630-8100 www.capitaladvisors.com Venture Capital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

SUPPORTER

Caraco Pharmaceutical Laboratories, Ltd.1150 Elijah McCoy Drive Detroit, MI 48202 (313) 871-8400 www.caraco.com Pharmaceutical & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

CardiArc7444 Haggerty Road Canton, MI 48187 (734) 207-3440 www.cardiarc.com Medical Devices

Cascade Hemophilia Consortium210 East Huron, Suite D Ann Arbor, MI 48104 (734) 996-3300 www.hemoalliance.org Association/Non-profit

Cascade Life Solutions3710 Sysco Court, SE Grand Rapids, MI 49512 (616) 977-2515 Medical Devices



Cerise Nutraceuticals, Inc.1670 Barlow Street, Suite A Traverse City, MI 49686 (231) 933-3300 www.cherrylotion.com Pharmaceutical & Therapeutics, Agriculture & Food

CFI Medical Solutions (Contour Fabricators, Inc.) 14241 Fenton Road Fenton, MI 48430 (810) 750-5300 www.cfimedical.com Medical Devices, Contract R&D

Charles River 9801 Shaver Road Portage, MI 49002 (269) 327-4248 www.criver.com Contract R&D

Christian Roux Ltd. 561 Woodlawn Ypsilanti, MI 48197 (734) 732-6671 www.hurricanecrutch.com Medical Devices

PREFERRED PROVIDER

Chubb Group of Insurance Companies 5440 Corporate Drive, Suite 300 P.O. Box 7078 Troy, MI 48007 (734) 741-1850 www.chubb.com Insurance Provider • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Cielo MedSolutions 3520 Green Court, Ste. 425 Ann Arbor, MI 48104 (734) 827-1000 www.cielomedsolutions.com Informatics

City of Marshall Economic Development 323 West Michigan Marshall, MI 49068 (269) 781-5183 ext. 1156 www.cityofmarshall.com Government/Economic Devevelopment • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Clean Air Technology 41105 Capital Canton, MI 48187 (734) 459-6320 www.cleanairtechnology.com Research Tools

Clinical Ligand Assay Society 3139 South Wayne Road Wayne, MI 48184 (734) 722-6290 www.clas.org Association/Non-profit

ClinSite, Inc. 24 Frank Lloyd Wright Drive, Lobby A Ann Arbor, MI 48106 (734) 930-3700 www.clinsite.com Contract R&D

ClinxusCook-DeVos Center for Health Sciences 301 Michigan Street NE, Suite 537 Grand Rapids, MI 49503 (616) 331-5854 www.clinxus.com Association/Non-profit

CNVGenes LLC 4995 Arrowhead Road West Bloomfield, MI 48323 (248) 682-3368 www.cnvgenes.com Research Tools, Diagnostics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

College Park Industries 17505 Helro Road Fraser, MI 48026 (586) 294-7950 www.college-park.com Medical Devices

Collet Consulting, LLC405 Awixa Road Ann Arbor, MI 48104 (734) 358-9015 Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Compendia Bioscience 110 Miller Avenue, Floor 2 Ann Arbor, MI 48104 (734) 929-3909 www.compendiabio.com Informatics, Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

ConceivexP.O. Box 31 5 East Main Street Saranac, MI 48881 (616) 452-2700 www.conceptionkit.com Medical Devices

Contented Hearts, Inc.11490 East G Avenue Galesburg, MI 49053 (269) 665-4420 www.contentedhearts.com Informatics

Corium International, Inc.4558 50th Street Grand Rapids, MI 49512 (616) 656-4563 www.coriumintl.com Contract R&D, Pharmaceutical & Therapeutics

PREFERRED PROVIDER

Cornerstone Benefits, llC1450 West Long Lake Road, Suite 250 Troy, MI 48098 (248) 641-3609 www.cornerstonebenefits.com Insurance Provider • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Covalent Medical, Inc.4750 South State Street, Suite 301 Ann Arbor, MI 48108 (734) 429-2451 www.covamed.com Medical Devices, Research Tools

Coy Laboratory Products Inc 14500 Coy Drive Grass Lake, MI 49240 (734) 475-2200 www.coylab.com Research Tools, Medical Devices • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

CRB Consulting Engineers 5250 Lovers Lane, Suite 130 Kalamazoo, MI 49002 (269) 342-9474 ext. 1046 www.crbusa.com Facilities & Construction • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •



Creative Technology Services 7444 Haggerty Road Canton, MI 48187 (734) 207-2600 www.ctsmius.com Medical Devices, Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Crissman Toxicologic Pathology, LLC2887 Oakhaven Court Midland, MI 48642 (989) 631-2790 Contract R&D

Critech Research, Inc. 525 Avis Drive, Suite 7 Ann Arbor, MI 48108 (734) 668-0005 www.critech.com Contract R&D, Informatics

Critical Signal Technologies 22600 Haggerty Road Farmington Hills, MI 48335 (888) 557-4462 www.criticalsignaltechnologies.com Medical Devices

CSM Group 100 West Michigan Avenue, Suite 200 Kalamazoo, MI 49007 (269) 746-5600 www.csmgroup.com Facilities & Construction • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Custom Biogenic Systems 150 Shafer Drive Romeo, MI 48065 (800) 523-0072 www.custombiogenics.com Research Tools, Medical Devices

Cutting Image Histology, LLC 800 Technology Drive Ann Arbor, MI 48108 (734) 945-9077 www.cuttingimagehistology.com Contract R&D, Diagnostics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Cybernet Medical, Cybernet Systems Corporation 727 Airport Boulevard Ann Arbor, MI 48108 (800) 292-3763 www.cybernetmedical.com Informatics, Medical Devices

CVR Gobal, Inc.18186 Park Lane Grosse Ile, MI 48138 (734) 604-6023 www.cvrgloabl.com Medical Devices

D

Danmar Products Inc. 221 Jackson Industrial Drive Ann Arbor, MI 48103 (800) 783-1998 www.danmarproducts.com Medical Devices

data integrated Scientific Systems 8031 Main Street, Suite 301 Dexter, MI 48130 (734) 426-4995 www.dissdata.com Informatics, Research Tools

Davis Dental Labs 5830 Crossroad Commerce Parkway Wyoming, MI 49519 (616) 261-9191 www.dentalservices.net/davis Medical Devices

DavisMade, Inc 2511 Davison Road Flint, MI 48506 (810) 742-0581 www.standingdani.com Medical Devices

DBA Analytical (an NSF International Company)789 Dixboro Road Ann Arbor, MI 48113 (734) 769 8010 www.dba-global.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Ddots, Inc. 4571 Ellsworth Road Ypsilanti, MI 48197 (734) 434-7734 www.ddots.com Informatics

deCODE genetics 1032 Karl Greimel Drive, Suite 11 Brighton, MI 48114 (810) 220-5300 www.decode.com Pharmaceuticals & Therapeutics, Diagnostics

Delphi Medical Systems 5725 Delphi Drive Troy, MI 48098 (248) 813-8061 www.delphimedical.com Medical Devices • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Dendritech, Inc. 3110 Schuette Drive Midland, MI 48642 (989) 496-2016 www.dendritech.com Industrial & Environmental

Dendritic Nanotechnologies, Inc.2625 Denison Drive, Suite B Mt. Pleasant, MI 48858 (989) 774-6565 www.dnanotech.com Industrial & Environmental

der-Balian inc 5027 Collins Road Manistee, MI 49660 (650) 380-1591 Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Dermanaut 702 Dwight Street Ypsilanti, MI 48198 (734) 604-8214 www.dermanaut.com Informatics

Detroit R & D, Inc. Metropolitan Center for High Technology (MCHT) 2727 Second Avenue, Suite 4113 Detroit, MI 48201 (313) 961-1606 www.detroitrandd.com Diagnostics, Research Tools

Detroit Technical Equipment Company 55 East Long Lake Road, PMB #433 Troy, MI 48085 (248) 232-8894 ext. 115 www.detroit-tech.com Lab Equipment • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •



Draths Industries, LLC 2367 Science Parkway, Suite 2 Okemos, MI 48864 (517) 349-0669 www.drathscorporation.com Agriculture & Food, Contract R&D, Industrial & Environmental

Drug & Laboratory Disposal, Inc.331 Broad Street Plainwell, MI 49080 (269) 685-9824 www.dld-inc.com Contract R&D, Industrial & Environmental • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

DuPeron Medical Systems 3195 South Christy Way Saginaw, MI 48603 (989) 790-5100 www.duperonmedical.com Contract R&D

SILVER SPONSOR

Dykema, PLLC 400 Renaissance Center Detroit, MI 48243 (313) 568-6800 Detroit www.dykema.com Attorneys • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

E

EADevices, Inc. 7752 Primrose Lane Portage, MI 49024 (412) 334-7045 Medical Devices

Early Warning Healthcare Institute 3100 Cross Creek Parkway, Suite 160 Auburn Hills, MI 48326 (248) 371-9000 www.earlywarninghealth.net Diagnostics, Informatics

ECO PHySICS, INC. 3915 Research Park, Suite A-3 Ann Arbor, MI 48108 (734) 998-1600 www.ecophysics-us.com Medical Devices, Research Tools

Ecology Health Products, Inc. 12941 East Townline Road Goetzville, MI 49736 (906) 297-8770 www.ecologyproducts.com Pharmaceuticals & Therapeutics, Agriculture & Food

EcoSynthetix 3900 Collins Road Lansing, MI 48910 (517) 336-4649 www.ecosynthetix.com Agriculture & Food, Industrial & Environmental

Eliason Consulting 440 Burroughs TechOne, Suite 320 Detroit, MI 48230 (301) 675-9983 Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Elkins Innovations, Inc. 301 Michigan Street, Suite 581 Grand Rapids, MI 49503 (616) 331-5889 Medical Devices

Eloquest Healthcare 780 West Eight Mile Road Ferndale, MI 48220 (877) 433-7626 www.eloquesthealthcare.com Pharmaceuticals & Therapeutics

Emerald BioAgriculture Corporation/Auxein Corporation2123 University Park Drive, Suite 105 Okemos, MI 48864 (517) 882-7370 www.emeraldbio.com Agriculture & Food, Industrial & Environmental

Emergent BioSolutions 3500 Martin Luther King Jr. Boulevard Lansing, MI 48906 (517) 327-1500 www.ebsi.com Pharmaceuticals & Therapeutics, Industrial & Environmental • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Emiliem 4717 Campus Drive Kalamazoo, MI 49009 (415) 421-0222 www.emiliem.com Pharmaceuticals & Therapeutics

Ennew Medical Devices, LLC 2400 N. 6th Street Kalamazoo, MI 49009 (269) 615-5113 Medical Devices

Diagnostic Instruments Inc. 6540 Burroughs Street Sterling Heights, MI 48314 (586) 731-6000 www.diaginc.com Medical Devices, Diagnostics, Research Tools • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

di-Coat Corp 42900 West Nine Mile Road Novi, MI 48375 (800) 637-9194 www.dicoat.com Manufacturer

Digilab Genomic Solutions 4355 Varsity Drive Ann Arbor, MI 48108 (734) 975-4800 www.genomicsolutions.com Research Tools

diversified natural Products 506 East State Street Scottville, MI 49454 (514) 276-3199 www.dnpworld.com

DNA Software, Inc. 204 East Washington Street Ann Arbor, MI 48104 (734) 222-9080 www.dnasoftware.com Informatics, Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

DNADNB LLC 4995 Arrowhead Road West Bloomfield, MI 48323 (248) 682-3368 Contract R&D, Diagnostics, Medial Devices, Research Tools

Doctor’s Orders, Inc 731 B Construction Court Zeeland, MI 49464 (616) 931-9939 www.do-engineering.com Medical Devices, Contract R&D

PREFERRED PROVIDER

Doeren Mayhew755 West Big Beaver, Suite 2300 Troy, MI 48084 (248) 244-3005 www.doeren.com Accountants, Financial Advisors • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •



Ernst & young LLP 171 Monroe Avenue NW, Suite 1000 Grand Rapids, MI 49503 (313) 628-7100 www.ey.com Accountants • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Esperion Therapeutics, Inc. 46701 Commerce Center Drive, Suite B Plymouth, MI 48170 (734) 862-4840 www.esperion.com Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Essen Instruments 1156 Oak Valley Drive Ann Arbor, MI 48108 (734) 769-1600 www.essen-instruments.com Research Tools, Medical Devices, Contract R&D

Eurofins Avtech laboratories, inc.6859 Quality Way Kalamazoo, MI 49002 (269) 323-3366 www.avtechlabs.com Contract R&D, Diagnostics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Exponent, Inc.39100 Country Club Drive Farmington Hills, MI 48331 (248) 324-9135 www.exponent.com Medical Devices, Industrial & Environmental, Contract R&D

ExT Lifesciences, Inc.2000 Town Center, Suite 2370 Southfield, MI 48075 (248) 948-6910 www.extlifesciences.com Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

EyeLab Group2350 Washtenaw, Suite 4 Ann Arbor, MI 48104 (734) 665-0567 Medical Devices

F

Farnell Equipment Company 2950 Todd Drive Troy, MI 48084 (248) 643-8890 www.farnell-equipment.com Lab Equipment • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Fermical, Inc. 1360 Hilton Ferndale, MI 48220 (248) 545-1656 Contract R&D, Pharmaceutical & Therapeutics

Ferndale Laboratories Inc. 780 West Eight Mile Road Ferndale, MI 48220 (248) 548-0900 www.ferndalelabs.com Pharmaceuticals & Therapeutics, Contract R&D, Medical Devices, Pharmaceutical • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

PREFERRED PROVIDER

Field Consulting Services, Inc.1010 North Wagner Road Ann Arbor, MI 48103 (734) 476-6425 www.fieldconsulting.biz IT Services & Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Field Neuroscience Institute 4677 Towne Centre Road, Suite 101 Saginaw, MI 48604 (989) 497-3117 www.fni.org Association/Non-profit

FlowTech Corporation 7601 Stadium Drive Kalamazoo, MI 49009 (269) 375-1290 www.flowtechfilters.com Research Tools, Medical Devices • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Fraunhofer USA CCL B100 Eng. Research Complex Michigan State University East Lansing, MI 48824 (517) 432-8711 www.ccl.fraunhofer.org Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Freeman Manufacturing Company 900 West Chicago Road Sturgis, MI 49091 (616) 651-2371 www.freemanmfg.com Medical Devices

Fulcrum Pharma Developments, Inc.900 Victors Way, Suite 1600 Ann Arbor, MI 48108 (734) 994-7394 www.fulcrumpharma.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Fullscope, Inc. 1399 Rand Road Canton, MI 48187 (734) 667-1204 www.fullscope.com IT Services & Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

G

GANTEC, Inc. 4520 East Ashman Road, Suite A Midland, MI 48642 (877) 816-9300 www.gantecinc.com Agriculture & Food

Garrison Dental Solutions 1010 DeWitt Lane Spring Lake, MI 49456 (616) 842-2430 www.garrisondental.com Medical Devices

GE Medical Systems InformationTechnology3300 Washtenaw Avenue, Suite 225 Ann Arbor, MI 48104 www.gehealthcare.com/usen/hit/index.html Informatics



GEMA, LLC 463 Rosewood Avenue East Lansing, MI 48823 (517) 775-3007 Diagnostics

Gene Codes 775 Technology Drive, Suite 100 Ann Arbor, MI 48108 (734) 769-7249 www.genecodes.com Informatics, Research Tools

GeneGo, Inc. 500 Renaissance Drive, Suite 106 St. Joseph, MI 49085 (888) 592-3124 www.genego.com Informatics, Research Tools • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Genemarkers LLC 2718 Oakland Drive Kalamazoo, MI 49008 (269 )998-8116 www.genemarkersllc.com Contract R&D, Diagnostics

Genentech 1 DNA Way South San Francisco, CA 94080 (650) 225-1000 www.gene.com Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Genetics Squared, Inc. 401 West Morgan Road Ann Arbor, MI 48104 (734) 929-9475 www.genetics2.com Pharmaceuticals & Therapeutics, Diagnostics, Informatics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

GeneVivo, LLC 800 Technology Drive Ann Arbor, MI 48108 (248) 231-4761 www.genevivo.com Contract R&D

Genomatix Software, Inc. 3025 Boardwalk, Suite 160 Ann Arbor, MI 48108 (877) 436-6628 www.genomatix-software.com Informatics, Contract R&D, Research Tools

Gerber Product Company, a Division of Nestlé Nutrition 445 State Street Fremont, MI 49413 (800) 284-9488 www.gerber.com Agriculture & Food

Gerontology Network 500 Cherry Street SE Grand Rapids, MI 49503 (616) 456-6135 www.michiganseniors.org Association/Non-profit

Gifford, Krass, Sprinkle, Anderson & Citkowski, PC P.O. Box 7021 Troy, MI 48007 (248) 647-6000 www.patlaw.com Attorneys • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Gift of Life Michigan 2203 Platt Road Ann Arbor, MI 48104 (800) 482-4881 www.giftoflifemichigan.org Association/Non-profit

Giri Diagnostics LLC 2611 Parmenter Boulevard Royal Oak, MI 48073 (248) 435-4472 www.giridiagnostics.com Research Tools, Diagnostics, Contract R&D

GlaxoSmithKline 7890 Charline Court Lewis Center, OH 43035 (740) 549-2426 www.gsk.com Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Global Clinical Connections MTEC at the Groves Kalamazoo Valley Community College 7107 Elm Valley Drive, Suite 2680 Kalamazoo, MI 49009 (269) 488-3277 www.globalclinicalconnections.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Global Remediation Technologies Incorporated 1102 Cass Street Traverse City, MI 49684 (800) 899-3703 www.grtusa.com Industrial & Environmental, Contract R&D

Global Strategic Connections, LLC2125 Butterfield Drive, Suite 218N Troy, MI, 48084 (248) 816-6881 www.gsc-llc.com Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

GlyTag LLC 32375 Lahser Road Beverly Hills, MI 48025 (313) 577-9827 www.glytag.com Pharmaceuticals & Therapeutics, Contract R&D, Research Tools

göteborgBio - BRg 3260 Homestead Court Saline, MI 48176 (734) 429-4961 www.goteborgbio.se Government/Economic Development • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Graminex, LLC 95 Midland Road Saginaw, MI 48638 (989) 797-5502 www.graminex.com Agriculture & Food, Pharmaceuticals & Therapeutics

Grand River Aseptic Pharmaceutical Packaging, inc. - Center for Excellence140 Front Avenue SW, Suite 3 Grand Rapids, MI 49504 (616) 644-0555 www.GrandRiverAPP.com Contract R&D

Grand Valley State University 100CHS 301 Michigan NE Grand Rapids, MI 49503 (616) 331-7192 www.gvsu.edu University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •



Grant Manufacturing Corporation10957 Old 27 Highway N. Vanderbilt, MI 49795 (989) 983-3641 www.granthealingenvironment.com Medical Devices

Great Lakes Angels, Inc. 568 Woodway Court, Suite 1 Bloomfield Hills, MI 48302 (248) 540-3758 www.glangels.org Angel Group • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Great Lakes Drug Development, Inc.1032 Karl Greimel Drive, Suite 11 Brighton, MI 48116 (810) 522-1903 www.gldrugdev.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Great Lakes Entrepreneur’squest 3520 Green Court, Suite 450 Ann Arbor, MI 48105 (734) 647-8951 www.gleq.org Government/Econ Dev. • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

H

HAC of America, Inc. 1111 West Centre Kalamazoo, MI 49024 (800) 445-9968 www.hacofamerica.com Medical Devices

Hamztec LLC 1039 Olivia Avenue Ann Arbor, MI 48104 (734) 476-8502 Medical Devices

Handy Lab, Inc. 5230 South State Street Ann Arbor, MI 48108 (734) 663-4719 www.handylab.com Research Tools

Hanger Prosthetics & Orthodics2314 Gull Road Kalamazoo, MI 49001 (616) 345-1117 www.hanger.com/Pages/HangerHome.aspx Medical Devices

Harness, Dickey & Pierce, PLC5445 Corporate Drive, Suite 400 Troy, MI 48098 (248) 641-1600 ext. 1241 www.hdp.com Attorneys • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Hart Enterprises, Inc. 400 Applejack Court Sparta, MI 49345 (616) 887-0400 www.hartneedles.com Medical Devices, Contract R&D

Harvard Drug Company31778 Enterprise Drive Livonia, MI 48150 (734) 525-8700 www.harvarddrugs.com Pharmaceuticals & Therapeutics

Haviland Enterprises 421 Ann NW Grand Rapids, MI 49504 (800) 456-1134 www.havilandusa.com Agriculture & Food, Industrial & Environmental

HealthCure, LLC 390 Park Street, Suite 110 Birmingham, MI 48009 (248) 282-9300 www.healthcure.biz Diagnostics, Industrial & Environmental, Informatics, Research Tools • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

HealthMedia, Inc. 130 South First Street Ann Arbor, MI 48104 (734) 623-0000 www.healthmedia.com Informatics

Healthtreat, Inc 30777 Northwestern Highway, Suite 300 Farmington Hills, MI 48334 (248) 855-0033 www.healthtreat.com Agriculture & Food

Henry Ford Medical Group &Hospital 2799 West Grand Boulevard Detroit, MI 48202 (313) 916-2024 www.Henryford.com University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

HistoSonics, LLC 7819 Kilbirnie Drive Portage, MI 49024 (269) 270-4387 Medical Devices • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Honigman Miller Schwartz &Cohn LLP 444 West Michigan Avenue Kalamazoo, MI 49007 (269) 337-7700 www.honigman.com Attorneys • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Horseshoe Herbals 1219 Anderson Road Niles, MI 49120 (269) 684-6888 www.horseherbs.bigstep.com Pharmaceuticals & Therapeutics

Housey Pharmaceutical Research Laboratories, LLC 16800 West 12 Mile Road, Suite 201 Southfield, MI 48076 (248) 663-7000 www.housey.com Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Hygieia, Inc. 330 East Liberty Street, Lower Level Ann Arbor, MI 48104 (734) 527-9160 www.hygieia.com Medical Devices

PREFERRED PROVIDER

Hylant Group 24 Frank Lloyd Wright Drive, Suite J4100 Ann Arbor, MI 48105 (734) 741-0044 www.hylant.com Insurance Provider • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •



I

i3 STATPROBE, Inc. 5430 Data Court, Suite 200 Ann Arbor, MI 48108 (734) 623-8346 www.i3statprobe.com Contract R&D

iDesign Solutions, LLC 2175 Lancaster Road, Suite 1 Bloomfield Hills, MI 48302 (248) 425-7992 www.idesign-solutions.info Facilities & Construction • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Implants International NA 220 East Huron Street, 3rd Floor Ann Arbor, MI 48104 (734) 645-8937 www.implantsinternational.com Medical Devices, Pharmaceuticals & Therapeutics, Research Tools

In the Groove, LLC 7600 Madeline Street Saginaw, MI 48609 (517) 781-6030 www.inthegroovebrace.com Medical Devices

Incept BioSystems 401 West Morgan Road Ann Arbor, MI 48108 (317) 508-6972 www.inceptbio.com Medical Devices, Research Tools

Inland Waters Pollution Control2021 South Schaefer Highway Detroit, MI 48217 (800) 992-9118 www.inlandwaters.com Industrial & Environmental, Contract R&D

Innovative Analytics Inc. 161 East Michigan Avenue Kalamazoo, MI 49007 (269) 488-3200 www.ianalytics.biz Contract R&D, Informatics

Innovative BioTherapies, Inc.401 West Morgan Road Ann Arbor, MI 48108 (734) 213-8350 ext. 301 www.innbio.com Pharmaceuticals & Therapeutics, Medical Devices

Innovative Cell Technology 30186 Walnut Court Farmington Hills, MI 48331 (313) 966-7324 Contract R&D

Innovative Research Inc 46430 Peary Court Novi, MI 48377 (248) 896-0145 www.innov-research.com Contract R&D, Diagnostics, Research Tools • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

INRAD, Inc. 4375 Donker Court SE Kentwood, MI 49512 (616) 301-7800 www.inrad-inc.com Medical Devices

Institute for Health Care StudiesMichigan State University D 132 West Fee Hall East Lansing, MI 48824 (517) 432-4325 www.ihcs.msu.edu University/Institution/Hospital

Institute for Health Studies4084 Okemos Road Okemos, MI 48864 (877) 908-2273 www.instituteforhealthstudies.com Universities/Institutions/Hospitals

Institute for Preventive SportsMedicine P.O. Box 7032 Ann Arbor, MI 48107 (734) 572-4577 www.ipsm.org University/Institution/Hospital, Association/Non-profit

Integrated Nonclinical Development Solutions, Inc. 3005 Miller Avenue Ann Arbor, MI 48103 (734) 929-5392 www.INDS-Inc.com Contract R&D, Informatics

Integrated Sensing Systems (ISSyS)391 Airport Industrial Drive Ypsilanti, MI 48198 (734) 547-9896 www.mems-issys.com Medical Devices, Research Tools

Intermediary Biochemicals, LLC2529 Dustin Road Okemos, MI 48864 Agriculture & Food, Industrial & Environmental, Research Tools

International Discovery SourcingConsultants LLC 300 North Main Street, Suite 202 Chelsea, MI 48118 (734) 433-9670 www.idscbiotechnetwork.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

International Partnership for Critical Markers of Disease (CMOD)828 West Grand River Avenue Brighton, MI 48116 (810) 494-7193 www.cmod.org Association/Non-profit

INVIA Medical Imaging Solutions3025 Boardwalk Street, Suite 200 Ann Arbor, MI 48108 (734) 205-1231 www.inviasolutions.com Informatics, Medical Devices

Invirion, Inc. 2350 Pilgrim Highway Frankfort, MI 49635 (866) 231-8378 www.invirion.com Diagnostics, Research Tools

J

J. Rettenmaier, USA 16369 US Highway 131 Schoolcraft, MI 49087 (269) 679-2340 www.jrs.usa.com Agriculture & Food, Industrial & Environmental

Jade Scientific 7855 Ronda Canton, MI 48187 (734) 207-3775 www.jadesci.com Research Tools



Jasper Clinical Research & Development, Inc.526 Jasper Street Kalamazoo, MI 49007 (269) 276-8899 www.jasperclinic.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

JHP Pharmaceuticals, Inc.870 Parkedale Road Rochester, MI 48307 (248) 656-5223 www.kingpharm.com Pharmaceuticals & Therapeutics

Jiva Pharma, Inc. 2245 South State Street, Suite 1100 Ann Arbor, MI 48104 (734) 262-0673 Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Johnson & Johnson P.O. Box 726 Langhorne, PA 19047 (517) 648-6767 www.jnj.com Pharmaceuticals& Therapeutics, Medical Devices, Diagnostics, Informatics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Juvenile Diabetes Research Foundation - Metro detroit & SE Michigan24359 Northwestern Highway, #225 Southfield, MI 48075 (248) 355-1133 www.jdrfdetroit.org

Juvenile Diabetes Research Foundation - West Michigan 5075 Cascade Road SE, Suite F Grand Rapids. MI 49546 (6160 957-1838 www.jdrf.org/westmichigan Association/Non-profit

JV Biolabs2245 South State Street Ann Arbor, MI 48104 (734) 395-7436 www.jvbiolabs.com Contract R&D, Research Tools

K

Kalexsyn, Inc. 4502 Campus Drive Kalamazoo, MI 49008 (269) 488-8488 www.kalexsyn.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

KAR Bioanalytical, Inc. 4425 Manchester Road Kalamazoo, MI 49001 (269) 381-9666 ext. 232 www.karbio.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Karmanos Cancer Institute 4100 John R. Detroit, MI 48201 (313) 576-8931 www.karmanos.org University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Kellogg Company One Kellogg Square P.O. Box 3599 Battle Creek, MI 49016 (800) 962-1413 www.kelloggcompany.com Agriculture & Food • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Kendle International 315 East Eisenhower Parkway, Suite 214 Ann Arbor, MI 48108 (734) 274-8500 www.kendle.com Contract R&D

Kestrel Consultants, Inc. 410 Rose Drive Ann Arbor, MI 48103 (734) 576-3031 www.KestrelConsultants.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Keweenaw Nanoscience Center747 7th Street Calumet, MI 49913 (906) 296-9072 www.nanosciencecenter.com Industrial & Environmental

Keystone Product Development5121 East ML Avenue, Suite B-10 Kalamazoo, MI 49048 (269) 746-9141 www.keystone-pd.com Contract R&D, Medical Devices

KOA Orthopedics 46985 Enterprise Drive, Suite A-100 Wixom, MI 48393 (248) 596-0250 www.koaorthopedics Medical Devices

Komodo Pharmaceutical Services, LLC 5121 East ML Avenue Kalamazoo, MI 49048 (269) 567-4260 www.komodops.com Contract R&D

Koppert Biological Systems, Inc.2856 South Main Street Ann Arbor, MI 48103 (734) 641-3763 www.agrobiologicals.com/company/C1195.htm Agriculture & Food

L

Lake Erie Medical and Surgical7560 Lewis Avenue Temperance, MI 48182 (734) 847-3847 Medical Devices

law Offices of gary Kendra, PC143 Cady Centre, #319 Northville, MI 48167 (248) 596-1879 www.kendralaw.com Attorneys • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Lead Biopharma Consulting, LLC7726 Brass Creek Court Dexter, MI 48130 (734) 418-2296 www.leadbiopharma.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

LEC Tech, Inc. 16647 Chandler Road East Lansing, MI 48823 (517) 332-4610 Agriculture & Food, Industrial & Environmental



Lenawee Intermediate SchoolDistrict 4107 North Adrian Highway Adrian, MI 49221 (517) 265-1610 www.lisd.us Education (K-12) • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Life Science Systems, Inc. 784 South Poseyville Road Midland, MI 48640 (989) 698-3067 www.tse-systems.com Contract R&D

PREFERRED PROVIDER

Linde LLCLinde Midwest Sales Office 2100 Western Court, Suite 100 Lisle, IL 60532 (734) 424-1327 www.lindeus.com Chemicals • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Lindsay Exhibit Group, Inc. 9281 East Michigan State Road 36 Whitmore Lake, MI 48189 (877) 885-7117 www.lindsayexhibits.com Marketing Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

L·VAD Technologies, Inc. 300 River Place, Suite 6850 Detroit, MI 48207 (313) 446-2800 www.lvadtech.com Medical Devices

PATRON

Lumigen, Inc. 22900 West Eight Mile Road Southfield, MI 48033 (248) 351-5600 www.lumigen.com Diagnostics, Research Tools • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Luminos LLC 1514 Eisenhower Place Ann Arbor, MI 48108 (734) 677-1774 www.luminosassays.com Diagnostics, Research Tools

Lycera Corporation 46701 North Commerce Center Drive, Suite C Plymouth, MI 48170 (734) 233-3060 www.lycera.com Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Lynn Medical Instruments 764 Denison Court P.O. Box 7027 Bloomfield Hills, MI 48302 (248) 338-6242 www.lynnmed.com Medical Devices

M

Mager Scientific inc.1100 Baker Road Dexter, MI 48130 (734) 426-8166 www.magersci.com Medical Devices

Mainline Technologies International 3985 Research Park Drive Ann Arbor, MI 48108 (734) 930-2043 Research Tools

PREFERRED PROVIDER

Mangosoft 29A Riverside Street Nashua, NH 03062 (888) 886-2646 www.mangosoft.com IT Services & Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

MarketLab P.O. Box 888374 Kentwood, MI 49588 (616) 656-2484 www.marketlabinc.com Lab Equipment

MasterControl, Inc.6322 South 3000 East, Suite 110 Salt Lake City, UT 84121 (801) 631-5381 www.mastercontrol.com IT Services & Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Maximax International Inc. 35560 Grand River, Suite# 292 Farmington Hills, MI 48335 (800) 374-5270 www.maximax.com Contract R&D

Mayaterials 661 Airport Boulevard., Suite 1 Ann Arbor, MI 48108 (734) 994-7035 www.talmaterials.com Industrial & Environmental

MBI International 3900 Collins Road Lansing, MI 48910 (517) 337-3181 www.mbi.org University/Institutions/Hospitals, Association/Non-profit, Industrial & Environmental

MC3, Inc 3550 West Liberty, Suite 3 Ann Arbor, MI 48103 (734) 995-9089 www.mc3corp.com Medical Devices, Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

McClinchey Histology Lab, Inc.P.O. Box 421 100 Rice Street Stockbridge, MI 49285 (517) 851-9149 www.mhistolab.com Contract R&D

McKesson Pharmacy Systems 30881 Schoolcraft Livonia, MI 48150 (734) 779-8800 www.mckesson.com Informatics

Mead Johnson Nutritionals, a Division of Bristo Myers Squibb Co725 East Main Street Zeeland, MI 49464 (812) 429-7795 www.meadjohnson.com Agriculture & Food

MedArray Inc.3915 Research Park Drive, Suite A-4 Ann Arbor, MI 48108 (734) 769-1066 www.permselect.com Medical Devices, Research Tools



Medbio, Inc. 630 South Division Avenue Grand Rapids, MI 49503 (616) 245-0214 www.medbioinc.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

MedElute, Inc. 259 East Michigan Avenue, Suite 407 Kalamazoo, MI 49007 (269) 352-3760 Medical Devices

Medical Accessories & ResearchCorporation219 North Church Street Zeeland, MI 49464 (616) 748-8950 www.medacc.com Medical Devices, Research Tools

Medical Device Launchpad34067 Grand River Avenue Farmington, MI 48335 www.medicaldevicelaunchpad.com Contract R&D

Medical Imaging Resources, Inc.120 Enterprise Drive Ann Arbor, MI 48103 (734) 426-3003 www.mobilemedicalimaging.com Medical Devices

MedImage, Inc.6276 Jackson Road, Suite G Ann Arbor, MI 48103 (734) 665-5400 www.medimage.com Medical Devices, Informatics, Contract R&D

Medi-nuclear Corp.30029 Research Drive New Hudson, MI 48165 (800) 423-4226 www.medinuc.com/index.html Medical Devices, Research Tools

Meditrina Pharmaceuticals, Inc.300 North Fifth Avenue, Suite 150 Ann Arbor, MI 48104 (734) 926-0966 www.meditrinapharma.com Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Medtronic620 Watson Street SW Grand Rapids, MI 49504 (616) 242-5200 www.medtronic.com Medical Devices

MemsTech 42503 Steepleview Northville, MI 48167 (7340 560-5506 www.memstech.com Medical Devices, Diagnostics

Merit Laboratories, Inc. 2680 East Lansing Drive East Lansing, MI 48823 (517) 332-0167 www.meritlabs.com Industrial & Environmental, Contract R&D

MERS, LLC799 Skynob Drive Ann Arbor, MI 48105 (734) 487-1251 www.mersllc.com Medical Devices, Micro and Nano/ Pharmaceuticals & Therapeutics

Metabolic Solutions Development Company 125 South Kalamazoo Mall, #202 Kalamazoo, MI 49007 (616) 464-5071 www.kalmetres.com/index.html Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Metagenx, LLC 4316 Aztec Way Okemos, MI 48864 (517) 203-0194 Informatics

3520 Green Court, Suite 450 Ann Arbor, MI 48105 (734) 527-9150 www.michbio.org Association/Non-profit • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Michigan Agri-Business Association1501 North Shore Drive, Suite A East Lansing, MI 48823 (517) 332-8663 www.miagbiz.org Association/Non-profit

Michigan Animal Model Consortium - Center for Technology Excellence 333 Bostwick Avenue Grand Rapids, MI 49503 (616) 234-5684 www.ctaalliance.org/cta-cores/michigan-animal-model-consortium University/Institution/Hospital, Contract R&D

Michigan Antibody TechnologyCenter - Center of TechnologyExcellence333 Bostwick Avenue NE Grand Rapids, MI 49503 (616) 234-5342 www.vai.org/Research/Labs/Antibody Technology.aspx University/Institution/Hospital, Contract R&D, Research Tools

Michigan Association of Health Plans327 Seymour Avenue Lansing, MI 48933 (517) 371-3181 www.mahp.org Association/Non-profit

Michigan Biological Imaging Center - Center for Technology ExcellenceDepartment of Biological Sciences 3425 Woodhall, Western Michigan University Kalamazoo, MI 49008 (269) 387-5640 www.wmich.edu/bios/facilities/imaging-center/index.html University/Institution/Hospital, Contract R&D

Michigan Biomass Energy Program 611 West Ottawa, P.O. Box 30221 Lansing, MI 48909 (517) 241-6223 www.michigan.gov/biomass Government/Economic Development

MEDIA SPONSOR

Michigan Business Review800 Monroe, Suite 213 Grand Rapids, MI 49503 (616) 222-5784 www.mlive.com/mbusinessreview Media • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •



Michigan Center for Biologicalinformation - Center for Technology Excellence3600 Green Court, Suite 700 Ann Arbor, MI 48105 (734) 615-5814 www.ctaalliance.org/MCBI University/Institution/Hospital

Michigan Chemistry Council 326 West Ottawa, Capitol Corners Lansing, MI 48933 (517) 372-8898 www.michiganchemistry.com Association/Non-profit

Michigan Citizens for Stem Cell Research and Cures (MCSCRC)27177 Lahser Road, Suite 102 Southfield, MI 48034 (248) 948-5555 www.StemCellResearchforMichigan.com Association/Non-profit

Michigan Corn Growers Association/Corn Marketing Program of Michigan 12800 Escanaba Drive, Suite B Dewitt, MI 48820 (517) 323-6600 www.micorn.org Association/Non-profit

Michigan Diagnostics LLC 2611 Parmenter Boulevard Royal Oak, MI 48073 (248) 435-4472 www.michdiag.com Contract R&D, Research Tools

PLATINUM SPONSOR

Michigan Economic Development Corporation 300 North Washington Square Lansing, MI 48913 (517) 373-9808 www.michiganadvantage.org Government/Economic Development • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Michigan Health & Hospital Association 6215 West St. Joseph Highway Lansing, MI 48917 (517) 323-3443 www.mha.org Association/Non-profit

Michigan Health Council 2410 Woodlake Drive, P.O. Box 30014 Okemos, MI 48864 (517) 347-3332 www.mhc.org Association/Non-profit

Michigan High Throughput Screening Center - Center of Technology ExcellenceKalamazoo Valley Community College 7107 Elm Valley Drive Kalamazoo, MI 49003 (269) 353-1582 www.mhtsc.kvcc.edu University/Institution/Hospital, Contract R&D

Michigan Instruments 717 Talon Court SE Grand Rapids, MI 49512 (616) 554-9696 ext. 305 www.michiganinstruments.com Medical Devices

Michigan Israel Business Bridge3520 Green Court, Suite 450 Ann Arbor, MI 48105 (734) 604-2479 www.michiganisrael.com Association/Non-profit • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Michigan Life Ventures, LLC 3605 Tanglewood Drive Ann Arbor, MI 48105 (734) 604-1994 Venture Capital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Michigan Medical Dental Association325 West Lake Lansing Road, Suite C East Lansing, MI 48823 (517) 332-8663 www.smilemichigan.com Association/Non-profit

Michigan Molecular Institute 1910 West Saint Andrews Road Midland, MI 48640 (989) 832-5550 www.mmi.org University/Institution/Hospital, Industrial & Environmental

Michigan Nurses Association 2310 Jolly Oak Road Okemos, MI 48864 (517) 349-5818 www.minurses.org Association/Non-profit

Michigan Orthopedic Services13450 Farmington Road Livonia, MI 48150 (734) 513-8205 www.michortho.com Medical Devices

Michigan Osteopathic Association2445 Woodlake Circle Okemos, MI 48864 (517) 347-1555 www.mi-osteopathic.org/index.php Association/Non-profit

Michigan Primary Care Association7215 Westshire Drive Lansing, MI 48917 (517) 381-8000 www.mpca.net Association/Non-profit

Michigan Research Institute 401 West Morgan Road Ann Arbor, MI 48108 (734) 302-3200 Association/Non-profit • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Michigan Science Teachers Association 3300 Washtenaw Avenue, Suite 220 Ann Arbor, MI 48104 (734) 973-0433 www.msta-mich.org Association/Non-profit

Michigan Small Business & Technology Development Center, Grand Valley State UniversitySeidman College of Business 510 West Fulton Street Grand Rapids, MI 49504 (616) 331-7480 www.misbtdc.org Government/Economic Development • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Michigan Soybean Promotion Committee 140 West Tuscola Street, P.O. Box 287 Frankenmuth, MI 48734 (989) 652-3294 www.michigansoybean.org Association/Non-profit



Michigan State Medical Society 120 West Saginaw East Lansing, MI 48826 (517) 337-1651 www.msms.org Association/Non-profit

Michigan State University - Michigan Center for Structural Biology - Center for Technology Excellence Department of Biochemistry 310 A Biochemistry East Lansing, MI 48824 (517) 355-0199 www.mcsb.bch.msu.edu University/Institution/Hospital

Michigan State University - MSU Technologies301 Administration Building East Lansing, MI 48824 (517) 355-5040 www.cga.msu.edu University/Institution/Hospital

SILVER SPONSOR

Michigan State University - Office of Research & graduate Studies120 West Saginaw East Lansing, MI 48826 (517) 337-1651 www.vprgs.msu.edu University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Michigan State University - Product Center for Agriculture and Natural Resources80 Agriculture Hall East Lansing, MI 48824 (517) 432-1676 www.productcenter.msu.edu University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Michigan Technological University Office of Technology and Economic Development1400 Townsend Drive, Harold Meese Building Houghton, MI 49931 (888) 688-1885 www.admin.mtu.edu/iptc University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Michigan Technology and Research Institute, LLC 2245 South State Street, Suite 1100 Ann Arbor, MI 48104 (734) 222-0013 www.MTRInstitute.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Michigan Universities Commercialization Initiative (MUCI) 3003 South State Street, Wolverine Tower Room 2071 Ann Arbor, MI 48109 (734) 647-5730 www.muci.org University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Michigan Venture Capital Association 425 North Main Street Ann Arbor, MI 48104 (734) 223-3750 www.michiganvca.org Association/Non-profit

Micro Machine Co. 2429 North Burdick Street Kalamazoo, MI 49007 (616) 388-2440 www.micromachineco.com Contract R&D, Medical Devices

Microbiological Associates, Inc.37428 Hills Tech Drive Farmington Hills, MI 48331 (248) 324-4800 www.microbioassociates.com Contract R&D, Agriculture & Food, Diagnostics

Microcide, Inc. 2209 Niagara Drive Troy, MI 48083 (888) 342-6279 www.microcideinc.com.com Agriculture & Food

MicroDose Life Sciences, LLC 37935 West12 Mile Road, Building 1, Suite A Farmington Hills, MI 48331 (248) 489-1190 www.micro-dose.com Venture Capital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Micromyx, LLC4717 Campus Drive Kalamazoo, MI 49008 (269) 372-3758 www.micromyx.com Contract R&D, Research Tools • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Midbrook, Inc.2080 Brooklyn Road Jackson, MI 49203 (517) 787-3481 www.midbrook.com Contract R&D, Medical Devices • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

MidMichigan Innovation Center4520 East Ashman Road, Suite M Midland, MI 48642 (989) 839-2333 www.mmic.us Government/Econ Dev.

Midwest Cleanroom Associates, Inc.2055 Oak Industrial Drive, Suite A Grand Rapids, MI 49505 (616) 458-8533 www.mcacleanrooms.com Facilities & Construction • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Miller, Canfield, Paddock & Stone, PLC840 West Long Lake Road, Suite 200 Troy, MI 48098 (313) 963-6420 www.millercanfield.com Attorneys • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

MIR Preclinical Services a Charles River Company800 Technology Drive Ann Arbor, MI 48108 (734) 821-1063 www.molecularimaging.com Contract R&D, Diagnostics

MMS Holdings Inc. 6880 Commerce Boulevard Canton, MI 48187 (734) 245-0310 www.mmsholdings.com Contract R&D



Molecular Innovations Inc. 21315 Hilltop Street Southfield, MI 48034 (248) 353-4900 ext. 10 www.mol-innov.com Research Tools, Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Molecular Therapeutics, Inc.800 Technology Drive, Suite 100 Ann Arbor, MI 48108 (734) 222-9900 www.moleculartherapeutics.com Pharmaceuticals & Therapeutics

Monal, Inc./Monal Labs 23611 Liberty Street Farmington, MI 48335 (248) 474-4557 www.MonalLabs.com Facilities & Construction • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

PREFERRED PROVIDER

Monitor Liability Managers Inc.2850 West Golf Road, Suite 800 Rolling Meadows, IL 60008 (800) 446-2100 www.monitorliability.com Insurance Provider • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Monteris Medical, Inc.4664 Campus Drive Kalamazoo, MI 49008 (269) 372-0455 www.monteris.com/index.htm Medical Devices

Motion Resources, Stryker Orthopedic 9487 Holly Road Grand Blanc, MI 48439 (810) 714-5500 www.stryker.com/en-us/products/Orthopae-dics/index.htm Medical Devices

MPI Research 54943 North Main Street Mattawan, MI 49071 (269) 668-3336 www.mpiresearch.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Mt. Clemens Orthopaedic Appliances, Inc.24432 Crocker Boulevard Clinton Township, MI 48036 (586) 463-3600 Medical Devices

MuciMed, Inc. 259 East Michigan Avenue, Suite 409 Kalamazoo, MI 49007 (906) 842-3212 Pharmaceuticals & Therapeutics

M-Vision 12420 Stanley Drive Belleville, MI 48111 (734) 697-3933 www.m-visioninc.com Medical Devices

Mycol Balm Laboratories, Inc. 9595 Raucholz Road St. Charles, MI 48655 (989) 585-3357 www.mycolbalm.com Pharmaceuticals & Therapeutics

N

NanoBio Corporation 2311 Green Road, Suite A Ann Arbor, MI 48105 (734) 302-4000 www.nanobio.com Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Nanoderm Therapeutics, Inc.3081 North Foxridge Court Ann Arbor, MI 48105 (734) 665-4105 Pharmaceuticals & Therapeutics

NanoMed Pharmaceuticals, Inc.7107 Elm Valley Drive, Room B1210 Kalamazoo, MI 49009 (269) 488-8525 www.nanomedpharm.com Contract R&D, Pharmaceutical & Therapeutics, Research Tools • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

NanoVir LLC 4717 Campus Drive, Suite 1300 Kalamazoo, MI 49008 (269) 372-3261 www.nanovirpharm.com Pharmaceuticals & Therapeutics

National Center for Manufacturing Sciences3025 Boardwalk Ann Arbor, MI 48108 (800) 222-6267 www.ncms.org Association/Non-profit • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

National Kidney Foundation of Michigan1169 Oak Valley Drive Ann Arbor, MI 48108 (734) 222-9800 www.nkfm.org Association/Non-profit

Natural Therapeutics, LLC401 West Morgan Road Ann Arbor, MI 48108 (734) 302-3200 www.fungalnailrelief.com/PrivacyPolicy.asp Pharmaceuticals & Therapeutics

PREFERRED PROVIDER

Nature Publishing Group75 Varick St., 9th Floor New York, NY 10013-1917 (212) 726-9760 www.nature.com Publisher • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Neocutis 11910 Fox Ridge Drive Plymouth, MI 48170 (734) 207-5104 www.neocutis.com Pharmaceuticals & Therapeutics

Neogen Corporation 620 Lesher Place Lansing, MI 48912 (800) 234-5333 www.neogen.com Agriculture & Food, Diagnostics, Research Tools, Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Nephrion, Inc. 401 West Morgan Road Ann Arbor, MI 48108 (734) 272-4772 www.nephrion.com Medical Devices, Diagnostics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •



NephRx Corporation 4717 Campus Drive, Suite 100 Kalamazoo, MI 49008 (269) 372-8703 www.nephrxcorp.com Pharmaceuticals & Therapeutics

NeuroNexus Technologies 3985 Research Park Drive, Suite 100 Ann Arbor, MI 48108 (734) 913-8858 www.neuralnexustech.com Medical Devices

Newport Consulting Group 7286 North Village Drive Clarkston, MI 48346 (248) 978-2000 www.newportconsgroup.com/index.html IT Services & Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Next Generation Therapeutics, Inc.2900 Huron Parkway, Suite 8 Ann Arbor, MI 48105 (734) 527-9139 www.nextgenerationtherapeutics.com/ default.aspx Contract R&D, Industrial & Environmental, Medical Devices, Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

NExT Mobility 7444 Haggerty Road Canton, MI 48187 (888) 489-6398 www.nextmobilitynow.com Medical Devices • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

NextGen Sciences, Inc.4401 Varsity Drive, Suite E Ann Arbor, MI 48108 (734) 973-7914 ext. 214 www.nextgensciences.com Contract R&D, Diagnostics, Research Tools

Nitrate Elimination Company, Inc.334 Hecla Street Lake Linden, MI 49945 (906) 296-1000 www.nitrate.com Research Tools

Northern Biomedical Research, Inc.930 West Sherman Boulevard Muskegon, MI 49441 (231) 759-2333 Contract R&D

northwest Orthotics- Prosthetic, Inc. 39830 Grand River, Suite BLD Novi, MI 48375 (248) 477-1443 Medical Devices

norwind-Cortez 305 North Hewitt Ypsilanti, MI 48197 (734) 434-0575 Medical Devices

NuStep 5111 Venture Drive, Suite 1 Ann Arbor, MI 48108 (734) 769-3939 www.nustep.com Medical Devices

Nymirum 117 North First Street Ann Arbor, MI 48105 (734) 604-9597 Pharmaceuticals & Therapeutics

O

Oakland County Planning & Economic Development1200 Pontiac Lake Road, Building 41W Waterford, MI 48328 (248) 858-9099 www.globaloakland.com Government/Economic Development • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

GOLD SPONSOR

Oakland University 520 Dowd Hall Rochester, MI 48309 (248) 370-2100 www.oakland.edu University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

OcuSciences, Inc. 3201 Asher Road Ann Arbor, MI 48104 (734) 646-4156 www.ocusciences.com Diagnostics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

PREFERRED PROVIDER

Office depot800 Eisenhower Parkway Ann Arbor, MI 48106 (734) 259-9281 www.officedepot.com Office Furniture, Supplier • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

O’Mara Products 3025 Sangra Avenue Grandville, MI 49118 (616) 531-9500 www.omaraproductsinc.com Lab Equipment • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Omega Surgical Instruments, Inc.G-8395 South Saginaw Street Grand Blanc, MI 48439 (800) 656-6342 www.omegasurgical.com Medical Devices

Ophthigenics LLC 2900 Huron Parkway, Suite 4 Ann Arbor, MI 48105 (734) 945-5408 www.ophthigenics.com Contract R&D

Optical Dimensions 711 East 4th Street Royal Oak, MI 48067 (248) 541-3790 www.opticaldimensionslab.com/default.aspx Medical Devices

Optical Supply 1526 Plainfield Avenue, NE Grand Rapids, MI 49505 (616) 361-6000 www.optical-supply.com Contract R&D, Medical Devices

Optim 30963 Woodward Avenue Royal Oak, MI 48073 (248) 551-0549 www.optimvalue.com Informatics

Orchard Unique 6688 Dixie Highway Bridgeport, MI 48722 (989) 746-0780 www.orchid-orthopedics.com/unique Contract R&D



Orchid Orthopedic Solutions, LLC1489 Cedar Street Holt, MI 48842 (517) 694-2300 www.macdeeinc.com Contract R&D, Medical Devices

Originus, Inc. 3985 Research Park Drive Ann Arbor, MI 48108 (734) 913-8791 www.originusinc.com Contract R&D, Research Tools • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Orthopedic Development, Inc.1400 Low Road Kalamazoo, MI 49008 (269) 544-4715 Industrial & Environmental, Medical Devices

OtoMedicine, Inc. 576 Romence Road, Suite 227 Portage, MI 49024 (269) 321-0265 www.otomedicine.com Agriculture & Food • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Oxford Biomedical Research, Inc.2165 Avon Industrial Drive Rochester Hills, MI 48309 (248) 852-8815 www.oxfordbiomed.com Contract R&D, Research Tools • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

P

Painex Corporation 18295 James Couzens Highway Detroit, MI 48235 (313) 863-1200 www.ringmasternow.com/index.html Pharmaceuticals & Therapeutics

Pall Corporation - life Sciences600 South Wagner Road Ann Arbor, MI 48103 (800) 521-3160 www.pall.com Research Tools, Medical Devices

Paragon Laboratories, Inc. 12649 Richfield Court Livonia, MI 48150 (734) 462-3900 www.paragonlaboratories.com Contract R&D

PBS Biotech 2529 Dustin Road Okemos, MI 48864 www.pbsbiotech.com Research Tools

Perrigo Company 515 Eastern Avenue Allegan, MI 49010 (269) 673-8451 www.perrigo.com Pharmaceuticals & Therapeutics, Contract R&D

GOLD SPONSOR

Pfizer inc. 7000 Portage Road Kalamazoo, MI 49001 (269) 833-4000 www.pfizer.com Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Phadia US 4169 Commercial Avenue Portage, MI 49002 (800) 346-4364 www.phadia.us Diagnostics, Research Tools

Pharmacision LLC 1947 Mistwood Court Canton, MI 48187 (734) 895-3670 www.pharmacision.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

PharmaMed Resources, LLC 790 Crosswind Lane Lindenhurst, IL 60046 (269) 303-0798 www.pharmamedresources.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

PharmMor Consulting, LLC P.O. Box 2570 Portage, MI 49081 (269) 327-2215 Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

PharmOptima, LLC 6710 Quality Way Portage, MI 49002 (269) 329-4370 www.pharmoptima.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Phillips Plastics Corporation 30230 Orchard Lake Road, Suite 150 Farmington Hills, MI 48334 (248) 851-8300 www.phillipsplastic.com Contract R&D

Phrixus Pharmaceuticals, Inc.300 North Fifth Avenue, Suite 150 Ann Arbor, MI 48104 (734) 358-9015 www.phrixuspharmaceuticals.com Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

GOLD SPONSOR PhRMA (Pharmaceutical Research and Manufacturers of America) 950 F Street, NW, Suite 300 Washington, DC 20004 (202) 835-3400 www.phrma.org Association/Non-profit • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

PhycoTech 620 Broad Street, Suite 100 St. Joseph, MI 49085 (616) 983-3654 www.phycotech.com Contract R&D, Research Tools

Pinnacle Insurance Partners 1430 Monroe NW, Suite 100 Grand Rapids, MI 49505 (800) 746-4253 ext. 126 www.pinnacleinsurancepartners.com Insurance Provider • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •



Pioneer Surgical Technology 375 River Park Circle Marquette, MI 49855 (906) 226-9909 www.pioneersurgical.com Medical Devices

Pixel Velocity Inc. 3917 Research Park Drive, Suite B7 Ann Arbor, MI 48108 (734) 213-3715 ext. 4200 www.pixel-velocity.com Medical Devices • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Plas-labs, inc. 401 East North Street Lansing, MI 48906 (517) 372-7177 www.plas-labs.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Plex Systems, Inc.1731 Harmon Road Auburn Hills, MI 48326 (248) 391-8000 www.plex.com IT Services & Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Pointe Scientific, inc. 5449 Research Drive Canton, MI 48188 (800) 445-9853 ext. 109 www.pointescientific.com Research Tools

POLy Bioinformatics 12191 East Austin Road Manchester, MI 48158 (734) 678-7342 www.polyergic.com Informatics

PREFERRED PROVIDER

PR Newswire LLC101 West Big Beaver Road, Floor 14 Troy, MI 48084 (734) 337-3401 www.prnewswire.com Media • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Precision Edge Surgical Products415 West 12th Avenue Sault Sainte Marie, MI 49783 (906) 632-4800 www.precisionedge.com Medical Devices

Price, Heneveld, Cooper, DeWitt & Litton 695 Kenmoor SE Grand Rapids, MI 49501 (616) 949-9610 www.priceheneveld.com Attorneys • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Progressive Dynamics Medical507 Industrial Road Marshall, MI 49068 (269) 781-4241 www.progressivedynamicsmedical.com Medical Devices

ProNAi Therapeutics, Inc. 4717 Campus Drive, Suite 1100 Kalamazoo, MI 49008 (269) 372-3289 www.pronai.com Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

ProPharma Group 8175 Creekside Drive Portage, MI 49024 (888) 242-0559 www.propharmagroup.com Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Pros-Tech 1717 Stephenson Highway Troy, MI 48083 (248) 680-2800 www.prostechctr.com Medical Devices

Prosthetic Center, Inc. 1200 South Washington Avenue Lansing, MI 48910 (517) 372-7007 Medical Devices

Proteos, Inc. 4717 Campus Drive Kalamazoo, MI 49008 (269) 372-3423 www.proteos.net Industrial & Environmental, Diagnostics, Contract R&D, Research Tools • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Protomatic 2125 Bishop Circle West Dexter, MI 48130 (734) 426-3655 www.protomatic.com Manufacturer

PTI Engineered Plastics, Inc.50900 Corporate Drive Macomb, MI 48044 (586) 263-5100 www.teampti.com Manufacturer, Plastics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

PVS Chemicals, Inc. 10900 Harper Avenue Detroit, MI 48213 (313) 921-1200 www.pvschemicals.com Industrial & Environmental

q

quality Care Products 7560 Lewis Avenue Temperance, MI 48182 (734) 847-3847 ext. 260 www.qcpmeds.com Pharmaceuticals & Therapeutics

quantum Laboratories 28221 Beck Road, Suite A-11 Wixom, MI 48393 (248) 348-7029 www.quantumlaboratories.com Contract R&D

quatRx Pharmaceuticals 777 East Eisenhower Parkway, Suite 100 Ann Arbor, MI 48108 (734) 913-9900 www.quatrx.com Pharmaceutical & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

quest Diagnostics Incorporated4444 Giddings Road Auburn Hills, MI 48326 Diagnostics, Contract R&D



quest Research Institute 31000 Telegraph, Suite 230 Bingham Farms, MI 48025 (248) 644-7770 www.questri.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

R

RADAR Medical Systems LLC 6632 Telegraph Road, Suite 333 Bloomfield Hills, MI 48301 (248) 626-9012 www.radarmed.com Informatics

Rader, Fishman & Grauer PLLC39533 Woodward Avenue, Suite 140 Bloomfield Hills, MI 48304 (248) 594-0600 www.raderfishman.com Attorneys • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Rapid BioSense 3900 Collins Road Lansing, MI 48910 (800) 579-4913 www.rapidbiosense.com Diagnostics, Medical Devices

Regulatory Affairs Associates, LLC30833 Northwestern Highway, Suite 121 Farmington Hills, MI 48334 (248) 855-5595 www.regaffairs.net Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

RG Medical Diagnostics 28351 Beck Road, Suite G5 Wixom, MI 48393 (888) 596-9498 www.rgmd.com Medical Devices

Richard-Allan Scientific 4481 Campus Drive Kalamazoo, MI 49008 (616) 644-2400 www.rallansci.com Research Tools

Rigaku Innovative Technologies1900 Taylor Road Auburn Hills, MI 48326 (248) 232-6400 www.rigaku.com Research Tools, Medical Devices

Riverside Organics 8100 Linden Detroit, MI 48238 (313) 933-0510 Contract R&D, Industrial & Environmental

RJL Systems, Inc. 33939 Harper Avenue Clinton Township, MI 48035 (586) 790-0200 ext. 103 www.rjlsystems.com Medical Devices, Research Tools • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Roche Biomedical Labs 32355 Capitol Street Livonia, MI 48150 (734) 525-0248 Contract R&D, Diagnostics

Rockwell Medical Technologies, Inc.30142 Wixom Road Wixom, MI 48393 (800) 449-3353 www.rockwellmed.com Medical Devices, Research Tools

Rose Technologies 1440 Front Avenue NW Grand Rapids, MI 49504 (616) 233-3000 www.rose-technologies.com Contract R&D

Roush Life Sciences 12068 Market Street Livonia, MI 48150 (734) 779-7752 www.roush.com Contract R&D, Medical Devices, Research Tools • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

RTI Health Solutions 3005 Boardwalk Street, Suite 105 Ann Arbor, MI 48108 (734) 213-5372 www.rtihs.org Contract R&D

Rubicon Genomics, Inc. 4370 Varsity Drive, Suite G Ann Arbor, MI 48108 (734) 677-6210 www.rubicongenomics.com Diagnostics, Contract R&D, Research Tools

RxDispense, Inc. 2706 Cumberland Berkley, MI 48072 (734) 277-0668 www.rxdispense.com Medical Devices

S

S & J Laboratories 4669 Executive Drive Portage, MI 49002 (269) 324-7383 www.sandjlab.com/index.html Contract R&D

Saline Lectronics, Inc. 710 North Maple Road Saline, MI 48176 (734) 944-2120 www.lectronics.net Manufacturer, Electronics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

SANDAB Group P.O. Box 2472 Birmingham, MI 48012 (248) 644-0011 www.sandab.com Contract R&D

SUPPORTER

sanofi-aventis US 55 Corporate Drive Bridgewater, NJ 08807 (636) 273-5409 www.sanofi-aventis.us/live/us/en/index.jsp Pharmaceutical & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

ScarPrev Pharmaceuticals 917 Packard Street Ann Arbor, MI 48104 (734) 717-9263 Pharmaceutical & Therapeutics

PREFERRED PROVIDER

Science Direct 3675 Crestwood Parkway, Suite 400 Duluth, GA 30096 (770) 935-6077 www.elsevier.com Information Services Provider • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •



SciTech Development LLC281 Kercheval Road Grosse Pointe Farms, MI 48236 (313) 576-8263 www.scitechdevelopment.com Medical Devices, Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

ScreenTrack 1603 Peach Street Ann Arbor, MI 48105 (734) 665-0701 Informatics

Secretory IgA Inc. 333 Parkland Plaza Drive Ann Arbor, MI 48104 (734) 994-0966 www.secretoryiga.com Pharmaceuticals & Therapeutics

Selective Technologies, Inc. 132 West First Street Flint, MI 48502 (810) 767-7530 Medical Devices

Sensound 221 Lewiston Road Grosse Pointe Farms, MI 48236 (313) 882-1065 www.sensound.com Medical Devices

Sentry Medical Technologies 1039 Olivia Avenue Ann Arbor, MI 48104 (734) 476-8502 Informatics

Sequenom Center for Molecular Medicine301 Michigan Street NE, Suite 580 Grand Rapids, MI 49503 (616) 391-4330 www.cmmdx.org Diagnostics, Research Tools

Shanghai Bio Corporation 21792 Cumberland Drive Northville, MI 48167 (248) 787-2757 www.ShanghaiBio.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Shrader Analytical and Consulting Laboratories, Inc. 3814 Vinewood Detroit, MI 48208 (313) 894-4440 www.shraderlabs.com Contract R&D

Siemens Ultrasound Division 400 West Morgan Ann Arbor, MI 48108 (734) 995-5010 www.usa.siemens.com/entry/en/?tab=healthcare Medical Devices

Signal Medical Corporation 400 Pyramid Marysville, MI 48040 (810) 364-7070 www.signalmd.com Medical Devices

Single Source Procurement, LLC6852 South 6th Street Kalamazoo, MI 49009 (269) 372-3997 www.sspusa.com Procurement Services • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Skyline Property Group, Inc. 2146 Livernois Troy, MI 48083 (248) 680-9900 ext. 212 Facilities & Construction • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Skytron 5085 Corporate Exchange Boulevard Grand Rapids, MI, 49512 (800) 759-8766 www.skytron.us Medical Devices

Slaughter Instrument Co. 4356 North Roosevelt Road Stevensville, MI 49127 (269) 428-7471 www.slaughtercoinc.com Medical Devices

Smith Haughey Rice & Roegge213 South Ashley, Suite 400 Ann Arbor, MI 48104 (734) 213-8000 www.shrr.com Attorneys • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

SOI HR Solutions58 Parkland Plaza, Suite 200 Ann Arbor, MI 48103 (734) 904-5611 www.soistaff.com/hr Human Resources • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

SoloHill Engineering, Inc.4370 Varsity Drive, Suite B Ann Arbor, MI 48108 (734) 973-2956 www.solohill.com Research Tools, Medical Devices

Somanetics Corporation1653 East Maple Road Troy, MI 48083 (248) 689-3050 www.somanetics.com Medical Devices

Sonetics Ultrasound, Inc.3550 West Liberty, Suite 3 Ann Arbor, MI 48103 (734) 260-4800 Medical Devices

Southwest Michigan First241 East Michigan Avenue Kalamazoo, MI 49024 (269) 553-9588 www.southwestmichiganfirst.com Government/Economic Development • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Southwest Michigan Innovation Center 4717 Campus Drive, Suite 100 Kalamazoo, MI 49008 (269) 353-1823 www.kazoosmic.com Government/Economic Development • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Sparton Medical Supply2400 East Ganson Street Jackson, MI 49202 (517) 787-8600 www.spartonmedicalsystems.com/index.htm Medical Devices, Contract R&D

SPI Pharma P.O. Box 226 Grand Haven, MI 49417 (231) 935-6900 www.spipharma.com Contract R&D



SSV Therapeutics, LLC2245 South State Street, Suite 1100 Ann Arbor, MI 48104 (734) 262-0673 Pharmaceuticals & Therapeutics

Sterling Diagnostics 36645 Metro Court Sterling Heights, MI 48312 (810) 979-9171 www.sterlingdiagnostics.com Research Tools, Diagnostics

Stryker Corporation 2825 Airview Boulevard Kalamazoo, MI 49002 (269) 385-2600 www.stryker.com Medical Devices

Stryker Instruments 4100 East Milham Avenue Kalamazoo, MI 49001 (269) 323-7700 www.stryker.com/instruments Medical Devices

Stryker Orthopaedics 44736 Helm Street Plymouth, MI 48170 (734) 454-0023 www.stryker.com/en-us/corporate/ContactUs/Orthopaedics/index.htm Medical Devices

SubTerra LLC P.O. Box 55 104 Wilcox Road White Pine, MI 49971 (906) 885-5953 www.subterrallc.com Agriculture & Food, Contract R&D

Surge Medical Solutions 3710 Sysco Court SE Grand Rapids, MI 49512 (616) 949-2392 www.surgemedical.com Medical Devices

Surgitel 77 Enterprise Drive Ann Arbor, MI 48103 (734) 996-9200 www.surgitel.com Medical Devices

PREFERRED PROVIDER

Switchback 300 North Fifth, Suite 120 Ann Arbor, MI 48104 (734) 418-8348 www.switchbackcms.com IT Services & Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Symmetry Jet 5212 Aurelius Road Lansing, MI 48911 (517) 882-4311 www.symmetrymedical.com Medical Devices

Synergy Group, Inc. 39400 Woodward Avenue, Suite 190 Bloomfield Hills, MI 48304 (248) 740-7400 www.synergygroup.biz/index.htm Facilities & Construction • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Systems Specialties 390 Enterprise Court, Suite 200 Bloomfield Hills, MI 48302 (248) 332-0099 www.sysspec.com Research Tools

T

Takeda Pharmaceuticals North America, Inc. One Takeda Parkway Deerfield, IL 60015 (715) 246-9930 www.tpna.com Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

TCF National Bank 301 North Main Street, Suite 100 Ann Arbor, MI 48104 (734) 669-5531 www.tcfbank.com Banking • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

TCH Pharmaceuticals, Inc. 300 North Fifth Avenue, Suite 150 Ann Arbor, MI 48104 (734) 926-0966 Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Team Pharmaceutical Inc.563 116th Avenue Martin, MI 49070 (269) 388-5708 Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Tech Initiatives Inc. 200 Michigan Street, Suite 408 Hancock, MI 49930 (906) 483-2676 www.cprmattress.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

TechTown 440 Burroughs, Entrepreneurial Suite Detroit, MI 48202 (313) 879-5250 www.techtownwsu.org/index.htm Government/Economic Development • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

TEdCo - Technology Enterprise Development Co., Inc. 3301 South Dort Highway, Suite 200 Flint, MI 48433 (734) 945-8789 www.tedcoinc.com Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Teresa M. Arnold & Associates8300 Adler Road Lambertville, MI 48144 (734) 854-1187 www.tmaapr.com Marketing Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

TERRE Clinical Research Services, Inc. 323 North First Street Ann Arbor, MI 48103 (734) 623-6454 www.terrecrs.com Contract R&D



Terumo Cardiovascular Systems Corp. 6200 Jackson Road Ann Arbor, MI 48103 (800) 521-2818 www.terumo-us.com Medical Devices, Research Tools • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Terumo Heart, Inc. 6180 Jackson Road Ann Arbor, MI 48103 (734) 741-6114 www.terumoheart.com Medical Devices

The Dow Chemical Company 2030 Dow Center Midland, MI 48674 (800) 258-2436 www.dowventurecapital.com Industrial & Environmental, Agriculture & Food • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

The MRI Insititute for Biomedical Research Imaging 440 East Ferry Street, Unit 2 Detroit, MI 48202 (313) 758-0065 www.mrimaging.com University/Institution/Hospital

The Point Services 1515 Chimney Ridge Traverse City, MI 49686 (231) 366-4121 www.thepointservcies.com Staffing and Recruiting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

The Right Place, Inc. 161 Ottawa Avenue NW, Suite 400 Grand Rapids, MI 49503 (616) 771-0325 www.rightplace.org Government/Economic Development • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Thompson Surgical Instruments10170 East Cherry Bend Road Traverse City, MI 49684 (313) 922-0177 www.thompsonsurgical.com Medical Devices

Thomson Healthcare 777 East Eisenhower Parkway Ann Arbor, MI 48108 (734) 913-3000 www.medstat.com Informatics

Thorn Smith Laboratories 7755 Narrow Gauge Road Beulah, MI 49617 (231) 882-4672 www.thornsmithlabs.com Research Tools

Threefold Sensors, LLC P.O. Box 1306 Ann Arbor, MI 48106 (734) 995-9338 www.threefoldsensors.com Diagnostics, Medical Devices

Thromgen 803 North Main Street Ann Arbor, MI 48104 (216) 368-1172 www.thromgen.com Pharmaceuticals & Therapeutics

Thumb Oilseed Producers 2145 Leppek Road Ubly, MI 48475 (989) 658-2344 www.thumboilseed.com Agriculture & Food

Tolera Therapeutics, Inc. 4717 Campus Drive Kalamazoo, MI 49008 (800) 695-1554 www.tolerainc.com Pharmaceutical & Therapeutics

Topspins, Inc. 403 Riverview Drive Ann Arbor, MI 48104 (734) 623-6400 www.topspins.com Medical Devices

Torrey Path LLC 255 East Liberty Street, Suite 273 Ann Arbor, MI 48104 (734) 418-8356 www.metamaticsllc.com Informatics

Tower Laboratories8060 Whitbeck Road Montague, MI 49437 (231) 893-1472 www.towerlabs.com Contract R&D

Toxicogenomic Informatics and Solutions, LLC P.O. Box 27482 Lansing, MI 48909 www.txisllc.com Contract R&D, Informatics

TransPharm Preclinical Solutions, LLC 7190 Brooklyn Road Jackson, MI 49201 (517) 536-8210 www.transpharmsite.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Trialon Corporation 5600 New King Street, Suite 345 Troy, MI 48098 (248) 205-2510 www.trialon.com Staffing and Recruiting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Trilithon Pharma, LLCMI (734) 637-3490 Pharmaceuticals & Therapeutics

Troy Polymers 330 East Maple Troy, MI 48083 (248) 733-1030 www.troypolymers.com Contract R&D

TSRL, Inc. 540 Avis Drive, Suite A Ann Arbor, MI 48108 (734) 663-4233 www.tsrlinc.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Twin Bay Medical, Inc. 11590 South US-31 Williamsburg, MI 49690 (231) 935-4370 www.barblock.com Medical Devices



U

Uckele Health and Nutrition P.O. Box 160 Blissfield, MI 49228 (800) 248-0330 www.uckele.com Agriculture & Food, Contract R&D

Ultralight Prosthetics, Inc. 24781 Five Mile Road Redford, MI 48239 (313) 538-8500 www.ultralightprostetics.com Medical Devices

Ultrasound Medical Devices, Inc.3917 Research Park, Suite B-7 Ann Arbor, MI 48108 (734) 369-5056 Medical Devices

Unival, Inc.2100 Commonwealth Boulevard, Suite 300 Ann Arbor, MI 48105 (800) 332-4463 www.unival-med.com Informatics

United BioSource Corporation2200 Commonwealth Boulevard, Suite 100 Ann Arbor, MI 48105 (734) 994-8940 www.unitedbiosource.com Contract R&D

University of Michigan - Biomedical Engineering 2200 Bonisteel Boulevard Ann Arbor, MI 48109 (734) 647-9926 www.bme.umich.edu University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

University of Michigan - Coulter Translational ResearchPartnership ProgramUniversity of Michigan Department of Biomedical Engineering 2200 Bonisteel Boulevard, 1131 Gerstacker Building Ann Arbor, MI 48109 (734) 615-9412 www.bme.umich.edu/research/coulter.php University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

University of Michigan - Life Sciences Institute210 Washtenaw Avenue Ann Arbor, MI 48109 (734) 763-1200 www.lsi.umich.edu University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

University of Michigan - Medical Innovation Center24 Frank Lloyd Wright Drive, Lobby M, Suite 2600 Ann Arbor, MI 48106 (734) 998-6994 www.med.umich.edu/ummic University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

University of Michigan - Michigan Center for Oral Health1011 North University, Room 3228 Ann Arbor, MI 48109 (734) 647-4622 www.dent.umich.edu/research/clinicalresearch University/Institution/Hospital

University of Michigan - Michigan Institute for Clinical Health Research24 Frank Lloyd Wright Drive, Lobby M Ann Arbor, MI 48106 (734) 998-7474 www.michr.umich.edu University/Institution/Hospital

University of Michigan - Michigan Nanotechnology Institute for Medicine and Biological Sciences1150 West Medical Center Drive, SPC 5648, 9220C MSRB III Ann Arbor, MI 48109 (734) 647-2777 www.nano.med.umich.edu University/Institution/Hospital

University of Michigan – Michigan Proteome Consortium - Center for Technology Excellence300 North Ingalls Building, 11th Floor, Room 1198 Ann Arbor MI, 48109 (734) 763-3130 www.proteomeconsortium.org University/Institution/Hospital, Contract R&D

SILVER SPONSOR

University of Michigan – Office of Vice President for Research4080 Fleming Building 503 Thompson Ann Arbor, MI 48109-1340 (734) 764-1185 www.research.umich.edu University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

University of Michigan - Technology Transfer Office 1214 South University, 2nd Floor Ann Arbor, MI 48104 (734) 763-0614 www.techtransfer.umich.edu University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

V

Van Andel Institute 333 Bostwick Avenue NE Grand Rapids, MI 49503 (616) 234-5000 www.vai.org University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

BRONZE SPONSOR

Varnum, Riddering, Schmidt & HowlettBridgewater Place, 333 Bridge Street NW Grand Rapids, MI 49501 (616) 336-6000 www.varnumlaw.com Attorneys • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Velcura Therapeutics, Inc. 4300 Varsity Drive, Suite D Ann Arbor, MI 48108 (734) 973-1000 www.velcura.com Pharmaceutical & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Velesco Pharma Services 3221 Heather Road Ann Arbor, MI 48108 (734) 545-0696 www.velescopharma.com Contract R&D • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •



VenOmix, Inc. 4717 Campus Drive, Suite 1200 Kalamazoo, MI 49008 (616) 889-9611 www.venomix.net Agriculture & Food, Industrial & Environmental, Pharmaceuticals & Therapeutics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Versus Technology, Incorporated2600 Miller Creek Drive Traverse City, MI 49684 (231) 946-5868 www.versustech.com Informatics

Vertellus Health and Specialty Products, LLC215 North Centennial Street Zeeland, MI 49464 (800) 223-0453 www.vertellus.com Contract R&D, Industrial & Environmental

VetGen, LLC 3728 Plaza Drive, Suite 1 Ann Arbor, MI 48108 (734) 669-8440 www.vetgen.com Contract R&D, Diagnostics

Vigor Equipment, Inc. 4915 Advance Way Stevenville, MI 49127 (269) 429-0191 www.vigorequipment.com Medical Devices

Virotech Co., Inc. 34279 Hazelwood Street Westland, MI 48186 (734) 620-0221 www.virotech-inc.com Pharmaceuticals & Therapeutics

Vortech Pharmaceuticals 6851 Chase Road Dearborn, MI 48126 (313) 584-4088 www.vortechpharm.com Pharmaceuticals & Therapeutics

PREFERRED PROVIDER

VWR International 1668 Chapleau Drive Ann Arbor, MI 48103 (800) 932-5000 www.vwr.com Lab Equipment • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

W

W.F. Valentine & Co. 7633 Quackenbush Reading, MI 49274 (517) 283-3143 www.horseshoes.com Pharmaceutical & Therapeutics

Wacker Chemical Corporation3301 Sutton Road Adrian, MI 49221 (517) 264-8793 www.wacker.com Industrial & Environmental, Agriculture & Food

Warde Medical Laboratory 300 West Textile Road Ann Arbor, MI 48108 (734) 214-0300 www.wardelab.com Contract R&D, Diagnostics

Warner Norcross & Judd LLP 900 Fifth Third Center 111 Lyon St NW, Suite 900 Grand Rapids, MI 49503 (616) 752-2000 www.wnj.com Attorneys • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

FRIEND

Wayne State University - Technology Commercialization5057 Woodward Avenue, Suite 6306 Detroit, MI 48202 (313) 577-5541 www.techtransfer.wayne.edu University/Institution/Hospital • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Wayne State University Applied genomic Technologies - Center for Technology ExcellenceWSU-5197, Biological Science Building 5047 Gullen Mall Detroit, MI 48202 (313) 577-3555 www.bioinformatics.wayne.edu/MCGT University/Institution/Hospital, Association/Non-profit, Industrial & Environmental

Welch Laboratories, Inc. 4270 Sunnyside Drive Holland, MI 49424 (616) 399-2711 www.welchlaboratories.com Contract R&D

West Michigan Regional Laboratory1726 Knollcrest Circle SE Grand Rapids, MI 49546 (616) 526-8440 www.calvin.edu/admin/wmrl Contract R&D

SUPPORTER

West Michigan Science and Technology Initiative 301 Michigan Street NE, Suite 537 Cook - DeVos Center for Health Sciences Grand Valley State University Grand Rapids, MI 49503 (616) 331-5840 www.wmsti.org Government/Economic Development • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Western Slope Laboratory 1197 Rochester Road, Suite K Troy, MI 48083 (248) 307-1168 www.westernslopelabs.com/index.shtml Contract R&D

Williams Syndrome AssociationP.O. Box 297 Clawson, MI 48017 (248) 244-2229 www.williams-syndrome.org Association/Non-profit

Wise BioStrategies LLC 820 Heatherway Ann Arbor, MI 48104 (734) 904-4489 Consulting • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

Working Bugs, LLC 16647 Chandler Road East Lansing, MI 48823 (517) 974-3030 www.workingbugs.com Contract R&D, Industrial & Environmental



x

xB TransMed Solutions, LLC 3133 Orchard Vista Drive SE Grand Rapids, MI 49546 (616) 234-5586 www.xbtransmed.com Informatics, Contract R&D

xG Sciences, Inc. 5020 Northwind Drive, Suite 212 East Lansing, MI 48823 (517) 203-1110 www.xgsciences.com Industrial & Environmental, Research Tools

xoran Technologies, Inc. 309 North First Street Ann Arbor, MI 48103 (734) 663-7194 www.xorantech.com Medical Devices, Diagnostics • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •

y

yourSurgery.com 7171 First Street West Bloomfield, MI 48324 (248) 334-2568 www.yoursurgery.com/Index.cfm Informatics

Z

zuSyn 4717 Campus Drive, Suite 100 Kalamazoo, MI 49008 (312) 997-2150 www.zusyn.com Pharmaceutical & Therapeutics



L IST ING By CATEGORy

Key to Listings by CategoryAccountants .............................................. 86

Agriculture & FoodBio-Based Technologies & Products ........... 86

Biochemicals............................................... 86

BioFuels ...................................................... 86

BioPlastics .................................................. 86

Biotechnology & GMOs .............................. 86

Feed Stock ................................................... 86

Food Products ............................................ 86

Food Safety ................................................. 86

Forestry....................................................... 86

Nutrition & Nutriceuticals .......................... 86

Plant-Based Therapeutics .......................... 86

Architects .................................................. 86

Association/Non-ProfitEducational ................................................. 86

Government Affairs .................................... 86

Medical ....................................................... 87

Attorneys ................................................... 87

Banks ......................................................... 87

Business Development ............................. 87

Business Funding ..................................... 87

Consulting ................................................. 87

Contract R&DAnalytical ................................................... 87

Animal Models/Transgenics ....................... 87

Chemistry ................................................... 87

Clinical Trial Development ......................... 88

Commercialization/Business Support ........ 88

Drug Development & Formulation ............. 88

Informatics ................................................. 88

Manufacturing/Production ........................ 88

Market Research & Strategy ....................... 89

Pharmacology ............................................. 89

Project Management ................................... 89

Prototype Development & Testing .............. 89

Regulatory & Compliance ........................... 89

Research & Technologies ............................ 90

Safety & Toxicology .................................... 90

Structural Biology & Drug Design .............. 90

Creative Services ...................................... 90

DiagnosticsBiochemical/Protein/Antibody................... 90

Biomarkers ................................................. 90

Biosensors................................................... 91

Genetic Testing & Index Arrays .................. 91

Imaging & Scans ......................................... 91

Molecular .................................................... 91

Electronics ................................................ 91

Employee Benefits .................................... 91

Engineering Services ............................... 91

Facilities & Construction......................... 91

Filter Media ............................................... 91

Financial Consultants .............................. 91

Freezer & Refrigeration Services ............ 91

Government Affairs .................................. 91

Government/Economic DevelopmentBusiness Development & Planning ............ 91

Incubators................................................... 91

Small Business Assistance .......................... 92

Human Resources .................................... 92

Industrial & EnvironmentalBio-Defense ................................................ 92

Bio-Plastics ................................................. 92

Chemicals ................................................... 92

Environmental Cleanup .............................. 92

Enzymes ..................................................... 92

Fermentation .............................................. 92

Nanotechnologies & Products .................... 92

White Biotechnology .................................. 92

InformaticsBio & Chem ................................................. 92

Data Capture & Management ..................... 92

Development ............................................... 93

Enterprise Management ............................. 93

Healthcare & Wellness ................................ 93

LIMS ........................................................... 93

Research ..................................................... 93

Information Services Provider ............... 93

Information Technology Services & Consulting .............................. 93

Insurance Providers ................................. 93

Lab Equipment ......................................... 93

Manufacturing Support ........................... 93

Marketing Consultants ............................ 93

Media ......................................................... 93

Medical DevicesDental ......................................................... 93

Diagnostics ................................................. 93

Hospital Equipment & Furnishings ............ 94

Lab Tools & Instruments ............................ 94

Medical Imaging ......................................... 94

Prosthetics & Orthotics .............................. 94

Safety .......................................................... 94

Sensors ....................................................... 95

Surgical ....................................................... 95

Therapeutic ................................................ 95

Office Furniture ........................................ 95

Pharmaceuticals & TherapeuticsAnimal Health ............................................ 95

Biologics & Biosimilars............................... 95

Cell-Based Therapies & Regenerative Medicine ............................... 96

Generics ...................................................... 96

Natural Products......................................... 96

Nutriceuticals & Alternative Medicines ...... 96

OTC ............................................................. 96

Synthetic Small Molecule ........................... 96

Vaccines ...................................................... 96

Procurement Services .............................. 96

Public Relations ........................................ 96

Real Estate ................................................. 96

Research ToolsInstruments & Equipment ......................... 96

Lab Furnishings .......................................... 97

Reagents & Materials .................................. 97

Testing & Kits ............................................. 97

Software ..................................................... 97

Staffing & Recruiting ............................... 97

Strategy/Planning .................................... 97

Supplier ..................................................... 97

Technical Writing ..................................... 97

University/Institution/HospitalAcademic/Education .................................. 98

Clinical/Hospital ......................................... 98

Contract Work ............................................. 98

Private ......................................................... 98

Public .......................................................... 98

Research ..................................................... 99

Tech Transfer .............................................. 99

Venture & Angel Capital ........................... 99




AccountantsDoeren MayhewErnst & Young LLP

Agriculture & Food - Bio-Based Technologies & ProductsAgriumBayer CropScienceCaltech Industries, Inc.Diversified Natural ProductsDraths Industries, LLCEcoSynthetixEmerald BioAgriculture Corporation / Auxein CorporationGANTEC, Inc.Graminex, LLCIntermediary Biochemicals, LLCJ. Rettenmaier, USAKoppert Biological Systems, Inc.LEC Tech, Inc.Neogen CorporationThe Dow Chemical CompanyVenOmix, Inc.

Agriculture & Food - BiochemicalsBayer CropScienceBurdick & JacksonDiversified Natural ProductsEmerald BioAgriculture Corporation / Auxein CorporationGANTEC, Inc.Haviland EnterprisesIntermediary Biochemicals, LLCLEC Tech, Inc.The Dow Chemical CompanyVenOmix, Inc.Wacker Chemical Corporation

Agriculture & Food - BioFuelsThe Dow Chemical Company

Agriculture & Food - BioPlasticsEcoSynthetixJ. Rettenmaier, USA

Agriculture & Food - Biotechnology & GMOsBayer CropScienceEmerald BioAgriculture Corporation / Auxein CorporationGANTEC, Inc.VenOmix, Inc.

Agriculture & Food - Feed StockBayer CropScienceDraths Industries, LLCJ. Rettenmaier, USAThe Dow Chemical CompanyUckele Health and Nutrition

Agriculture & Food - Food ProductsCerise Nutraceuticals, Inc.Gerber Product CompanyGraminex, LLCHealthtreat, IncKellogg CompanyMead Johnson NutritionalsThumb Oilseed ProducersUckele Health and Nutrition

Agriculture & Food - Food SafetyMicrobiological Associates, Inc.Microcide, Inc.Neogen CorporationThumb Oilseed ProducersUckele Health and Nutrition

Agriculture & Food - ForestryJ. Rettenmaier, USA

Agriculture & Food - nutrition & NutriceuticalsCerise Nutraceuticals, Inc.Diversified Natural ProductsEcology Health Products, Inc.Gerber Product CompanyGraminex, LLCHaviland EnterprisesHealthtreat, IncKellogg CompanyMead Johnson NutritionalsUckele Health and Nutrition

Agriculture & Food - Plant Based TherapeuticsSubTerra LLC

ArchitectsCRB Consulting EngineersiDesign Solutions, LLCMidwest Cleanroom Associates, Inc.

Association/non-Profit - EducationalAmerican Diabetes AssociationAmerican Society for MicrobiologyAmerican Society of EmployersCascade Hemophilia Consortium

Clinical Ligand Assay SocietyField Neuroscience InstituteGerontology NetworkGift of Life MichiganInstitute for Health StudiesInternational Partnership for Critical Markers of Disease (CMOD)Juvenile Diabetes Research Foundation - Metro Detroit & SE MichiganJuvenile Diabetes Research Foundation - West MichiganMichBioMichigan Agri-Business AssociationMichigan Association of Health PlansMichigan Chemistry CouncilMichigan Citizens for Stem Cell Research and Cures (MCSCRC)Michigan Corn Growers Association/Corn Marketing Program of MichiganMichigan Health & Hospital AssociationMichigan Health CouncilMichigan Israel Business BridgeMichigan Medical Dental AssociationMichigan Nurses AssociationMichigan Osteopathic AssociationMichigan Primary Care AssociationMichigan Science Teachers AssociationMichigan Soybean Promotion CommitteeMichigan State Medical SocietyMichigan Venture Capital AssociationNational Kidney Foundation of MichiganPhRMA (Pharmaceutical Research and Manufacturers of Americas)Williams Syndrome Association

Association/non-Profit - Government AffairsAmerican Society of EmployersCanadian Consulate GeneralMichBioMichigan Agri-Business AssociationMichigan Association of Health PlansMichigan Corn Growers Association/Corn Marketing Program of MichiganMichigan Health & Hospital AssociationMichigan Health CouncilMichigan Medical Dental AssociationMichigan Nurses AssociationMichigan Osteopathic AssociationMichigan Primary Care AssociationMichigan Soybean Promotion CommitteeMichigan State Medical SocietyMichigan Venture Capital AssociationPhRMA (Pharmaceutical Research and Manufacturers of America)



Associations/non-Profit - MedicalAmerican Diabetes AssociationCascade Hemophilia ConsortiumClinical Ligand Assay SocietyClinXusField Neuroscience InstituteGerontology NetworkGift of Life MichiganInstitute for Health StudiesInternational Partnership for Critical Markers of Disease (CMOD)Juvenile Diabetes Research Foundation - Metro Detroit & SE MichiganJuvenile Diabetes Research Foundation - West MichiganMichigan Association of Health PlansMichigan Health & Hospital AssociationMichigan Health CouncilMichigan Medical Dental AssociationMichigan Nurses AssociationMichigan Osteopathic AssociationMichigan Primary Care AssociationMichigan State Medical SocietyNational Kidney Foundation of MichiganPhRMA (Pharmaceutical Research and Manufacturers of America)Williams Syndrome Association

AttorneysBrinks, Hofer, Gilson & LioneBrooks KushmanButzel LongDykema, PLLCGifford, Krass, Sprinkle, Anderson & Citkowski, P.C.Harness, Dickey & Pierce, P.L.C.Honigman Miller Schwartz and Cohn LLPLaw Offices of Gary Kendra, PCMiller, Canfield, Paddock & Stone, P.L.C.Price, Heneveld, Cooper, DeWitt & LittonRader, Fishman & Grauer PLLCSmith Haughey Rice & RoeggeVarnum, Riddering, Schmidt & HowlettWarner Norcross & Judd LLP

BanksBank of Ann ArborTCF National Bank

Business DevelopmentAP Bio-Consulting LLCApjohn Group, LLCAptuit Consulting, IncBiotechnology Business Consultants (BBC)Collet Consulting, LLC

Field Consulting Services, Inc.Global Strategic Connections, LLCMichigan Biomass Energy ProgramMichigan Life Ventures, LLCMichigan Small Business & Technology Development CenterSouthwest Michigan Innovation CenterTEDCo - Technology Enterprise Development Co., Inc.Wise BioStrategies LLC

Business FundingAnn Arbor SPARKAutomation AlleyBiosciences Research and Commercialization Center - Center for Technology ExcellenceGreat Lakes Entrepreneur’s QuestMichigan Economic Development CorporationSouthwest Michigan FirstSouthwest Michigan Innovation CenterTechTownWest Michigan Science and Technology Initiative

ConsultingAP Bio-Consulting LLCApjohn Group, LLCAptuit Consulting, IncBeaumont Services Company LLCBiotechnology Business Consultants (BBC)Caladium ConsultingCollet Consulting, LLCDer-Balian IncEliason ConsultingGlobal Strategic Connections, LLCNational Center for Manufacturing SciencesPharmaMed Resources, LLCProPharma GroupSOI HR SolutionsTEDCo - Technology Enterprise Development Co., Inc.Wise BioStrategies LLC

Contract R&d - AnalyticalAAPharmaSyn LLCAbsolute Analytical, IncAEGIS EnvironmentsAntel BioSystems, IncAzoRx, Inc.Bio-Chem Laboratories, Inc.DBA Analytical (an NSF International Company)Eurofins Avtech Laboratories, Inc.Ferndale Laboratories Inc.Giri Diagnostics LLC

Global Remediation Technologies IncorporatedKAR Bioanalytical, Inc.MPI ResearchNextGen Sciences, Inc.Paragon Laboratories, Inc.PharmOptima, LLCPhycoTechPlas-Labs, Inc.Quantum LaboratoriesRoche Biomedical LabsS & J LaboratoriesShanghai Bio CorporationShrader Analytical and Consulting Laboratories, Inc.SPI PharmaTSRL, Inc.Velesco Pharma ServicesWarde Medical LaboratoryWestern Slope Laboratory

Contract R&d - Animal Models/TransgenicsArbor Preclinical & Consulting, LLCCharles RiverGeneVivo, LLCInnovative Research Inc.JV BiolabsMichigan Animal Model Consortium - Center for Technology ExcellenceMIR Preclinical Services (a Charles River Company)MPI ResearchNorthern Biomedical Research, Inc.PharmOptima, LLCTransPharm Preclinical Solutions, LLCTSRL, Inc.West Michigan Regional Laboratory

Contract R&d - ChemistryAAPharmaSyn LLCAlbemarle CorporationAlluvium Biosciences, Inc.AzoRx, Inc.Bio-Chem Laboratories, Inc.Boro Pharm, LLCBridge Organics Co.DBA Analytical (an NSF International Company)Draths Industries, LLCFermical, Inc.Giri Diagnostics LLCGrand River Aseptic Pharmaceutical Packaging, Inc.Kalexsyn, Inc.Next Generation Therapeutics, Inc.Plas-Labs, Inc.




Contract R&d - Chemistry continued...Riverside OrganicsShrader Analytical and Consulting Laboratories, Inc.Vortech PharmaceuticalsWelch Laboratories, Inc.

Contract R&d - Clinical Trial DevelopmentAnn Arbor Clinical ResearchAzoRx, Inc.Beaumont HospitalsBioPharma Data ServicesBioSTAT Consultants, Inc.Borgess Research InstituteClinSite, Inc.ClinXusExponent, Inc.Ferndale Laboratories Inc.Fulcrum Pharma Developments, Inc.Henry Ford Health SystemGreat Lakes Drug Development, Inc.i3 STATPROBE, Inc.Innovative Analytics Inc.Institute for Health StudiesInternational Discovery Sourcing Consultants LLCJasper Clinical Research & Development, Inc.KAR Bioanalytical, Inc.Karmanos Cancer InstituteKendle InternationalKestrel Consultants, Inc.Maximax International Inc.MMS Holdings Inc.Quest Research InstituteRTI Health SolutionsTERRE Clinical Research Services, Inc.United BioSource CorporationUniversity of Michigan - Michigan Institute for Clinical Health Research

Contract R&d - Commercializa-tion/Business SupportBeaumont Commercialization CenterBiosciences Research of Commercialization Center - Center for Technology ExcellenceMC3, Inc.Medical Device LaunchpadPharmicision, LLCPharmMor Consulting, LLCSANDAB GroupTech Initiatives Inc.

Contract R&d - drug Development & FormulationAccess Business GroupADMETRxArbor Preclinical & Consulting, LLCAzoRx, Inc.BioSTAT Consultants, Inc.CeeTox, Inc.Charles RiverCorium International, Inc.Eurofins Avtech Laboratories, Inc.Fulcrum Pharma Developments, Inc.Global Clinical ConnectionsInnovative Analytics Inc.Innovative Cell TechnologyIntegrated Nonclinical Development Solutions, Inc.International Discovery Sourcing Consultants LLCJasper Clinical Research & Development, Inc.Kendle InternationalKomodo Pharmaceutical Services, LLCMcClinchey Histology Lab, Inc.Michigan Technology and Research Institute, LLCMMS Holdings Inc.MPI ResearchNanoMed Pharmaceuticals, Inc.Next Generation Therapeutics, Inc.Northern Biomedical Research, Inc.Perrigo CompanyPharmOptima, LLCS & J LaboratoriesShanghai Bio CorporationSPI PharmaTERRE Clinical Research Services, Inc.TSRL, Inc.Velesco Pharma Services

Contract R&d - informaticsAIS ConsultingAltarumArbor Research Collaborative for HealthArivium, Inc.BioPharm Data ServicesBlueWare, Inc.Compendia BioscienceCritech Research, Inc.DNA Software, Inc.Genomatix Software, Inc.Integrated Nonclinical Development Solutions, Inc.Toxicogenomic Informatics and Solutions, LLCXB TransMed Solutions, LLC

Contract R&d - Manufacturing/ProductionAccess Business GroupAEGIS EnvironmentsAlbemarle CorporationAlluvium Biosciences, Inc.Ash StevensATEK Medical ManufacturingAvalon Laboratories LLCBoro Pharm, LLCBridge Organics Co.CFI Medical Solutions (Contour Fabricators, Inc.)Corium International, Inc.Creative Technology ServicesDi-Coat CorpDoctor’s Orders, IncDraths Industries, LLCDuPeron Medical SystemsFerndale Laboratories Inc.Fraunhofer USA CCLGrand River Aseptic Pharmaceutical Packaging, Inc. - Center for Technology ExcellenceHart EnterprisesKalexsyn, Inc.Keystone Product DevelopmentKomodo Pharmaceutical Services, LLCMedbio, Inc.Michigan Animal Model Consortium - Center for Technology ExcellenceMicro Machine Co.Midbrook, Inc.Next Generation Therapeutics, Inc.Optical SupplyOrchard Unique Orchid Orthopedic Solutions, LLCOxford Biomedical Research, Inc.Perrigo CompanyPhillips Plastics CorporationPlas-Labs, Inc.Proteos, Inc.ProtomaticRiverside OrganicsRose TechnologiesRoush Life SciencesSaline Lectronics, Inc.Sparton Medical SystemsSPI PharmaSubTerra LLCTower Laboratories MontagueTroy PolymersUckele Health and NutritionVertellus Health and Specialty Products, LLCVortech PharmaceuticalsWelch Laboratories, Inc.Working Bugs, LLC



Contract R&d - Market Research & StrategyAzoRx, Inc.DNADNB LLCInternational Discovery Sourcing Consultants LLCKeystone Product DevelopmentLead Biopharma Consulting, LLCMedical Device LaunchpadPharmacision LLCSANDAB Group

Contract R&d - PharmacologyArbor Preclinical & Consulting, LLCAzoRx, Inc.BioSTAT Consultants, Inc.CeeTox, Inc.Charles RiverInnovative Analytics Inc.Integrated Nonclinical Development Solutions, Inc.International Discovery Sourcing Consultants LLCJV BiolabsKAR Bioanalytical, Inc.Kendle InternationalLead Biopharma Consulting, LLCMicromyx, LLCMIR Preclinical Services (a Charles River Company)MPI ResearchNorthern Biomedical Research, Inc.PharmOptima, LLCTransPharm Preclinical Solutions, LLCWest Michigan Regional Laboratory

Contract R&d - Project ManagementAIS ConsultingAP Bio-Consulting LLCAptuit Consulting, IncArbor Research Collaborative for HealthArivium, Inc.AzoRx, Inc.Beaumont Commercialization CenterBiotechnology Business Consultants (BBC)Caladium ConsultingCollet Consulting, LLCCritech Research, Inc.CSM GroupFulcrum Pharma Developments, Inc.Global Clinical ConnectionsGlobal Strategic Connections, LLCGreat Lakes Drug Development, Inc.

i3 STATPROBE, Inc.Inland Waters Pollution ControlInnovative Analytics Inc.Integrated Nonclinical Development Solutions, Inc.International Discovery Sourcing Consultants LLCKestrel Consultants, Inc.Lead Biopharma Consulting, LLCMaximax International Inc.MC3, Inc.Medical Device LaunchpadMichigan Technology and Research Institute, LLCMidwest Cleanroom Associates, Inc.Monal, Inc./Monal LabsMPI ResearchNewport Consulting GroupOrchard Unique Pharmacision LLCPharmMor Consulting, LLCProPharma GroupRTI Health SolutionsTEDCo - Technology Enterprise Development Co., Inc.TERRE Clinical Research Services, Inc.United BioSource CorporationWise BioStrategies LLC

Contract R&d - Prototype Development & TestingATEK Medical ManufacturingAvalon Laboratories LLCBeaumont Commercialization CenterBeaumont Services Company LLCCreative Technology ServicesDoctor’s Orders, Inc.DuPeron Medical SystemsExponent, Inc.Fraunhofer USA CCLHart EnterprisesKeystone Product DevelopmentMC3, Inc.Medbio, Inc.Micro Machine Co.Orchard Unique Orchid Orthopedic Solutions, LLCPhillips Plastics CorporationProtomaticRose TechnologiesRoush Life SciencesSaline Lectronics, Inc.Sparton Medical SystemsTroy Polymers

Contract R&d - Regulatory & ComplianceAccess Business GroupAIS ConsultingAnn Arbor Clinical ResearchAptuit Consulting, Inc.AzoRx, Inc.Beaumont Commercialization CenterBioPharma Data ServicesBioSTAT Consultants, Inc.Caladium ConsultingCeeTox, Inc.Charles RiverDBA Analytical (an NSF International Company)DuPeron Medical SystemsEurofins Avtech Laboratories, Inc.Exponent, Inc.Fulcrum Pharma Developments, Inc.Global Clinical ConnectionsGreat Lakes Drug Development, Inc.i3 STATPROBE, Inc.Innovative Analytics Inc.Integrated Nonclinical Development Solutions, Inc.International Discovery Sourcing Consultants LLCJasper Clinical Research & Development, Inc.KAR Bioanalytical, Inc.Kendle InternationalKestrel Consultants, Inc.Keystone Product DevelopmentKomodo Pharmaceutical Services, LLCLead Biopharma Consulting, LLCMasterControl, Inc.Maximax International Inc.Medical Device LaunchpadMichigan Technology and Research Institute, LLCMicromyx, LLCMMS Holdings Inc.MPI ResearchNewport Consulting GroupOrchard Unique Pathology Experts, LLCPharmaMed Resources, LLCPharmMor Consulting, LLCPharmOptima, LLCProPharma GroupRegulatory Affairs Associates, LLCRTI Health SolutionsSOI HR SolutionsSparton Medical SystemsTERRE Clinical Research Services, Inc.TransPharm Preclinical Solutions, LLCUnited BioSource Corporation




Contract R&d - Research & TechnologiesAbsolute Analytical, Inc.AIS ConsultingAntel BioSystems, Inc.ApoLife, Inc.AquaBiochip, LLCArbor Preclinical & Consulting, LLCAsterand, Inc.AzoRx, Inc.Biodiscovery, LLCBiotech Clinical LaboratoriesCell Culture Characterization ServicesCharles RiverCutting Image Histology, LLCEssen InstrumentsFermical, Inc.Fraunhofer USA CCLGenemarkers LLCGiri Diagnostics LLCGlyTag LLCInnovative Research Inc.Lead Biopharma Consulting, LLCMerit Laboratories, Inc.Michigan Antibody Technology Center - Center of Technology ExcellenceMichigan Diagnostics LLCMichigan High Throughput Screening Center - Center of Technology ExcellenceMicromyx, LLCMIR Preclinical Services (a Charles River Company)Molecular Innovations Inc.MPI ResearchNanoMed Pharmaceuticals, Inc.NextGen Sciences, Inc.Northern Biomedical Research, Inc.Ophthigenics LLCOriginus, Inc.Paragon Laboratories, Inc.PharmOptima, LLCPhycoTechRoche Biomedical LabsRubicon Genomics, Inc.Shanghai Bio CorporationShrader Analytical and Consulting Laboratories, Inc.Toxicogenomic Informatics and Solutions, LLCTransPharm Preclinical Solutions, LLCTroy PolymersTSRL, Inc.VetGen, LLCWarde Medical LaboratoryWest Michigan Regional LaboratoryWestern Slope LaboratoryWorking Bugs, LLC

Contract R&d - Safety & ToxicologyAbsolute Analytical, Inc.ADMETRxAEGIS EnvironmentsAnn Arbor Clinical ResearchAntel BioSystems, Inc.AquaBiochip, LLCArbor Preclinical & Consulting, LLCAzoRx, Inc.Bio-Chem Laboratories, Inc.BioSTAT Consultants, Inc.Biotech Clinical LaboratoriesCeeTox, Inc.Charles RiverCrissman Toxicologic Pathology, LLCCutting Image Histology, LLCDBA Analytical (an NSF International Com-pany)Drug & Laboratory Disposal, Inc.Eurofins Avtech Laboratories, Inc.Exponent, Inc.Fermical, Inc.Fulcrum Pharma Developments, Inc.Global Remediation Technologies IncorporatedInland Waters Pollution ControlInnovative Analytics Inc.Integrated Nonclinical Development Solutions, Inc.International Discovery Sourcing Consultants LLCJasper Clinical Research & Development, Inc.JV BiolabsKAR Bioanalytical, Inc.Kendle InternationalMcClinchey Histology Lab, Inc.Merit Laboratories, Inc.Michigan Biological Imaging Center - Center for Technology ExcellenceMichigan Technology and Research Institute, LLCMicrobiological Associates, Inc.Micromyx, LLCMIR Preclinical Services (Molecular Imaging Research)MPI ResearchNorthern Biomedical Research, Inc.Paragon Laboratories, Inc.Pathology Experts, LLCPharmOptima, LLCPhycoTechQuantum LaboratoriesRoche Biomedical LabsS & J LaboratoriesShanghai Bio CorporationTERRE Clinical Research Services, Inc.

Toxicogenomic Informatics and Solutions, LLCTransPharm Preclinical Solutions, LLCWarde Medical LaboratoryWestern Slope Laboratory

Contract R&d - Structural Biology & Drug DesignAAPharmaSyn LLCDNA Software, Inc.Michigan Center for Structural Biology - Center for Technology Excellence

Creative ServicesGlobal Strategic Connections, LLCLindsay Exhibit Group, Inc.Teresa M. Arnold & Associates

diagnostics - Biochemical/ Protein/AntibodyAntel BioSystems, Inc.Armune BioScience, Inc.Assay Designs, Inc.Becton Dickinson - Difco LaboratoriesBiomedical Diagnostics, LLCBiotech Clinical LaboratoriesCayman Chemical CompanyCell Culture Characterization ServicesCutting Image Histology, LLCDetroit R & D, Inc.Eurofins Avtech Laboratories, Inc.Giri Diagnostics LLCHealthCure, LLCNeogen CorporationOxford Biomedical Research, Inc.Phadia USProteos, Inc.Quest Diagnostics IncorporatedRoche Biomedical LabsSterling DiagnosticsThreefold Sensors, LLCVirotech Co., Inc.Warde Medical Laboratory

diagnostics - BiomarkersArmune BioScience, Inc.Assay Designs, Inc.Becton Dickinson - Difco LaboratoriesBiomedical Diagnostics, LLCBiotech Clinical LaboratoriesCayman Chemical CompanyCell Culture Characterization ServicesCutting Image Histology, LLCDetroit R & D, Inc.Eurofins Avtech Laboratories, Inc.Innovative Research Inc.



Invirion, Inc.Johnson & JohnsonNextGen Sciences, Inc.OcuSciences, Inc.Oxford Biomedical Research, Inc.Phadia USQuest Diagnostics IncorporatedRoche Biomedical LabsRubicon Genomics, Inc.Sequenom Center for Molecular MedicineSterling DiagnosticsVirotech Co., Inc.Warde Medical Laboratory

diagnostics - BiosensorsBiotectixCVR Global, Inc.MemsTechRapid BioSenseThreefold Sensors, LLC

diagnostics - genetic Testing & Index ArraysAntel BioSystems, Inc.AquaBiochip, LLCBauer BioMedical, LLCdeCODE geneticsGenemarkers LLCInvirion, Inc.Michigan Technology and Research Institute, LLCQuest Diagnostics IncorporatedRoche Biomedical LabsRubicon Genomics, Inc.Sequenom Center for Molecular MedicineVetGen, LLCWarde Medical Laboratory

diagnostics - imaging & ScansCutting Image Histology, LLCCVR Global, Inc.Diagnostic Instruments Inc.Early Warning Healthcare InstituteMIR Preclinical Services (a Charles River Company)OcuSciences, Inc.Xoran Technologies, Inc.

diagnostics - MolecularAntel BioSystems, Inc.Armune BioScience, Inc.Bauer BioMedical, LLCBecton Dickinson - Difco LaboratoriesBiomedical Diagnostics, LLC

Biotech Clinical LaboratoriesCell Culture Characterization ServicesCNVGenes LLCCutting Image Histology, LLCDNADNB LLCGEMA, LLCGenetics Squared, Inc.Giri Diagnostics LLCInvirion, Inc.Lumigen, Inc.Luminos LLCPhadia USQuest Diagnostics IncorporatedRoche Biomedical LabsRubicon Genomics, Inc.Sequenom Center for Molecular MedicineSterling DiagnosticsVirotech Co., Inc.Warde Medical Laboratory

Electronics ManufacturerSaline Electronics

Employee BenefitsCornerstone Benefits, LLCHylant GroupPinnacle Insurance Partners

Engineering ServicesBeaumont Services Company LLCKeystone Product DevelopmentMidwest Cleanroom Associates, Inc.Monal, Inc./Monal LabsProPharma Group

Facilities & ConstructionBeaumont Services Company LLCCRB Consulting EngineersCSM GroupDetroit Technical Equipment CompanyiDesign Solutions, LLCMidwest Cleanroom Associates, Inc.Monal, Inc./Monal LabsSkyline Property Group, Inc.Synergy Group, Inc.

Filter MediaPall Corporation - Life Sciences

Financial ConsultantsBank of Ann ArborCornerstone Benefits, LLCDoren MayhewErnst & Young LLPHylant Group

Freezer & Refrigeration ServicesBruce Johnson Service Co.,Inc.

Government AffairsBrooks KushmanButzel LongDykema LLCMiller, Canfield, Paddock & Stone, PLC

Government/Economic DevelopmentAnn Arbor SPARKAutomation AlleyCanadian Consulate GeneralCity of Marshall Economic DevelopmentGoteborgBio - BRGMichBioMichigan Biomass Energy ProgramMichigan Economic Development CorporationMichigan Israel Business BridgeMichigan Small Business & Technology Development CenterOakland County Planning & Economic DevelopmentSouthwest Michigan FirstSouthwest Michigan Innovation CenterTechTownThe Right Place, Inc.West Michigan Science and Technology Initiative

Government/Economic development - Business Development & PlanningAnn Arbor SPARKAutomation AlleyCanadian Consulate GeneralOakland County Planning & Economic DevelopmentSouthwest Michigan FirstThe Right Place

Government/Economic development - incubatorsAnn Arbor SPARKAutomation AlleyCentral Michigan University - Center for Applied Research & TechnologyGoteborgBio - BRGMichigan Life Science and Innovation CenterMichigan Research InstituteMidMichigan Innovation CenterMTEC




government/Economic development - Incubators continued...OUInc.Southwest Michigan FirstSouthwest Michigan Innovation CenterTechTownUniversity Corporate Research ParkWest Michigan Science and Technology Initiative

Government/Economic development - Small Business AssistanceAnn Arbor SPARKAutomation AlleyGreat Lakes Entrepreneur’s QuestMichigan Biomass Energy ProgramMichigan Economic Development CorporationMichigan Small Business & Technology Development CenterMidMichigan Innovation CenterOakland County Planning & Economic DevelopmentSouthwest Michigan FirstSouthwest Michigan Innovation CenterTechTownThe Right Place, Inc.West Michigan Science and Technology Initiative

Human ResourcesAmerican Society of EmployersSOI HR Solutions

industrial & Environmental - Bio-defenseAbsolute Analytical, Inc.AEGIS EnvironmentsCaltech Industries, Inc.Emergent BioSolutionsMicrobiological Associates, Inc.Plas-Labs, Inc.

industrial & Environmental - Bio-PlasticsThe Dow Chemical Company

industrial & Environmental - ChemicalsAEGIS EnvironmentsBio-lab, Inc., A Chemtura CompanyBiopolymer InnovationsBridge Organics Co.Burdick & JacksonDendritech, Inc.Dendritic Nanotechnologies, Inc.Diversified Natural Products

Draths Industries, LLCDrug & Laboratory Disposal, Inc.EcoSynthetixEmerald BioAgriculture Corporation / Auxein CorporationHaviland EnterprisesIntermediary Biochemicals, LLCJ. Rettenmaier, USAPVS Chemicals, Inc.Riverside OrganicsThe Dow Chemical CompanyVenOmix, Inc.Vertellus Health and Specialty Products, LLCWacker Chemical Corporation

industrial & Environmental - Environmental CleanupAbsolute Analytical, Inc.Bio-lab, Inc., A Chemtura CompanyCaltech Industries, Inc.Drug & Laboratory Disposal, Inc.Global Remediation Technologies IncorporatedHealthCure, LLCInland Waters Pollution ControlMerit Laboratories, Inc.

industrial & Environmental - EnzymesBio-lab, Inc., A Chemtura CompanyProteos, Inc.

industrial & Environmental - FermentationAlluvium Biosciences Inc.Diversified Natural ProductsDraths Industries, LLCLEC Tech, Inc.MBI InternationalWorking Bugs, LLC

industrial & Environmental - Nanotechnolgies & ProductsBiotectixDendritech, Inc.Dendritic Nanotechnologies, Inc.Exponent, Inc.Keweenaw Nanoscience CenterMayaterialsMERS, LLCMichigan Molecular InstituteNext Generation Therapeutics, Inc.Orthopedic Development, Inc.Plas-Labs, Inc.The Dow Chemical CompanyXG Sciences, Inc.

industrial & Environmental - White BiotechnologyDraths Industries, LLCThe Dow Chemical Company

informatics - Bio & ChemBioMedPharmIS, Ltd.Compendia BioscienceData Integrated Scientific SystemsDNA Software, Inc.Gene CodesGeneGo, Inc.Genetics Squared, Inc.Genomatix Software, Inc.MetagenX, LLCPOLY BioinformaticsThomson HealthcareTorrey Path LLCToxicogenomic Informatics and Solutions, LLCXB TransMed Solutions, LLC

informatics - data Capture & ManagementAgfa CorporationAIS ConsultingArbor Research Collaborative for HealthAvicenna Medical Systems, Inc.BioMedware Inc.BioPharma Data ServicesCompendia BioscienceCritech Research, Inc.Data Integrated Scientific SystemsDdots, Inc.DermanautGE Medical Systems Information TechnologyGene CodesGenomatix Software, Inc.HealthCure, LLCInnovative Analytics Inc.Integrated Nonclinical Development Solutions, Inc.INVIA Medical Imaging SolutionsKestral Consultants, Inc.McKesson Pharmacy SystemsMedImage, Inc.OcuSciences, Inc.POLY BioinformaticsRADAR Medical Systems LLCSentry Medical TechnologiesThomson HealthcareToxicogenomic Informatics and Solutions, LLCUnival, Inc.Versus Technology, IncorporatedXB TransMed Solutions, LLC



informatics - developmentArivium, Inc.BioPharma Data ServicesCompendia BioscienceDdots, Inc.GE Medical Systems Information TechnologyThomson HealthcareXB TransMed Solutions, LLC

informatics - Enterprise ManagementAgfa CorporationBlueWare, Inc.Centromine, Inc.Cielo MedSolutionsContented Hearts, Inc.Cybernet MedicalDdots, Inc.DermanautGE Medical Systems Information TechnologyMcKesson Pharmacy SystemsMedImage, Inc.OptimRADAR Medical Systems LLCScreenTrackSentry Medical TechnologiesThomson HealthcareUnival, Inc.

informatics - healthcare & WellnessArbor Research Collaborative for HealthAvicenna Medical Systems, Inc.Better Rehab, LLCBioMedware Inc.BlueWare, Inc.Centromine, Inc.Cielo MedSolutionsContented Hearts, Inc.Critech Research, Inc.Cybernet MedicalDdots, Inc.Early Warning Healthcare InstituteGE Medical Systems Information TechnologyLinde LLCHealthMedia, Inc.Johnson & JohnsonMcKesson Pharmacy SystemsPOLY BioinformaticsRADAR Medical Systems LLCThomson HealthcareUnival, Inc.Versus Technology, IncorporatedYourSurgery.com

informatics - liMSData Integrated Scientific SystemsINVIA Medical Imaging SolutionsScreenTrackThomson Healthcare

informatics - ResearchArbor Research Collaborative for HealthBioMedPharmIS, Ltd.BioMedware Inc.BioSTAT Consultants, Inc.Compendia BioscienceCritech Research, Inc.Data Integrated Scientific SystemsDdots, Inc.GE Medical Systems Information TechnologyGene CodesGeneGo, Inc.Genetics Squared, Inc.Genomatix Software, Inc.Innovative Analytics Inc.Michigan Center for Biological Information - Center for ExcellencePOLY BioinformaticsThomson HealthcareTorrey Path LLCToxicogenomic Informatics and Solutions, LLCXB TransMed Solutions, LLC

Information Services ProviderBioMedPharmIS, Ltd.Nature Publishing Co.PharmacisionScience Direct

Information Technology Services & ConsultingArivium, Inc.CSM GroupField Consulting Services, Inc.Fullscope, Inc.MangosoftMasterControl, Inc.Newport Consulting GroupPlex SystemsProPharma GroupSwitchback

Insurance ProvidersBrown & Brown of DetroitChubb Group of Insurance CompaniesCornerstone Benefits, LLCHylant GroupMonitor Liability Managers Inc.Pinnacle Insurance Partners

Lab EquipmentBruce Johnson Service Co.,Inc.Calibrate, Inc. - The Pipet PeopleDetroit Technical Equipment CompanyFarnell Equipment CompanyMarketLabO’Mara ProductsVWR International

Manufacturing SupportBeaumont Services Company LLCCalibrate, Inc. - The Pipet PeopleField Consulting Services, Inc.Global Strategic Connections, LLCNational Center for Manufacturing SciencesPlex SystemsPTI Engineered Plastics, Inc.

Marketing ConsultantsAP Bio-Consulting LLCBiotechnology Business Consultants (BBC)Global Strategic Connections, LLCLindsay Exhibit Group, Inc.Teresa M. Arnold & AssociatesWise BioStrategies LLC

MediaMichigan Business ReviewPR Newswire

Medical devices - dentalAir Force Inc.Akervall TechnologiesAmerican Dental Technologies, Inc.Axenic Dental, Inc.Bio-Coat Inc.Davis Dental LabsGarrison Dental SolutionsSurgitel

Medical devices - diagnosticsAgfa CorporationAngott Medical Products, LLCCritical Signal TechnologiesDNADNB LLCIncept BioSystemsINRAD, Inc.Life Science Systems, Inc.MedArray Inc.MedtronicNorwind-CortezRG Medical DiagnosticsRJL Systems, Inc.RxDispense, Inc.SensoundSiemens Ultrasound Division




Medical devices - diagnostics continued...Somanetics CorporationSonetics Ultrasound, Inc.Terumo Heart, Inc.Xoran Technologies, Inc.

Medical devices - hospital Equipment & FurnishingsAmigo Mobility InternationalBiotronic Neural Monitoring SpecialistsCascade Life SolutionsCFI Medical Solutions (Contour Fabricators, Inc.)Creative Technology ServicesCritical Signal TechnologiesCustom Biogenic SystemsCybernet MedicalDelphi Medical SystemsEnnew Medical Devices, LLCFlowTech CorporationGrant Manufacturing CorporationJohnson & JohnsonLake Erie Medical and SurgicalLynn Medical InstrumentsMedical Imaging Resources, Inc.Medi-Nuclear Corp.MedtronicMichigan InstrumentsMidbrook, Inc.NEXT MobilityNuStepRG Medical DiagnosticsRJL Systems, Inc.Rockwell Medical Technologies, Inc.SkytronStryker CorporationSurge Medical SolutionsSurgitelTech Initiatives Inc.Terumo Cardiovascular Systems Corp.Twin Bay Medical, Inc.Vigor Equipment, Inc.

Medical devices - lab Tools & InstrumentsAdvanced Photonix Inc.ASI Instruments, Inc.Aspen Surgical Products, Inc.Ateq CorporationAtodyne Technologies LLCAutocam MedicalBioFlow Technology, Inc.BioLumix, Inc.Biophotonic Solutions, Inc.Biotronic Neural Monitoring Specialists

Cascade Life SolutionsCovalent Medical, Inc.Coy Laboratory Products Inc.Critical Signal TechnologiesCustom Biogenic SystemsCybernet MedicalDiagnostic Instruments Inc.DNADNB LLCEADevices, Inc.Essen InstrumentsFlowTech CorporationGrant Manufacturing CorporationHart EnterprisesIncept BioSystemsIntegrated Sensing Systems (ISSYS)Johnson & JohnsonKeystone Product DevelopmentKOA OrthopedicsLake Erie Medical and SurgicalLife Science Systems, Inc.Lynn Medical InstrumentsMager Scientific Inc.MC3, Inc.MedArray Inc.Medical Accessories & Research CorporationMedtronicNephrion, Inc.NeuroNexus TechnologiesOmega Surgical Instruments, Inc.Pall Corporation - Life SciencesPlas-Labs, Inc.Precision Edge Surgical ProductsProtomaticRG Medical DiagnosticsRoush Life SciencesSlaughter Instrument Co.SoloHill Engineering, Inc.Stryker CorporationStryker InstrumentsSurge Medical SolutionsSurgitelTerumo Cardiovascular Systems Corp.Terumo Heart, Inc.Twin Bay Medical, Inc.

Medical devices - Medical ImagingAdvanced Photonix Inc.Advanced X-Ray Technology, Inc.Agfa CorporationAngott Medical Products, LLCAxsys Technologies, Inc.CardiArcCVR Global, Inc. Diagnostic Instruments Inc.

INVIA Medical Imaging SolutionsMager Scientific Inc.Medical Imaging Resources, Inc.MedImage, Inc.M-VisionOcuSciences, Inc.Pixel Velocity Inc.Rigaku Innovative TechnologiesSensoundSiemens Ultrasound DivisionSonetics Ultrasound, Inc.SurgitelUltrasound Medical Devices, Inc.Xoran Technologies, Inc.

Medical devices - Prosthetics & OrthoticsBecker OrthopedicBioProBremer Prosthetics, Inc.Brenner Orthotic and Prosthetic LabsCFI Medical Solutions (Contour Fabricators, Inc.)Christian Roux Ltd.College Park IndustriesDavisMade, Inc.Elkins Innovations, Inc.Freeman Manufacturing CompanyHanger Prosthetics & OrthodicsLake Erie Medical and SurgicalMichigan Orthopedic ServicesMotion Resources, Styker OrthopedicMt. Clemens Orthopaedic Appliances, Inc.Northwest Orthotics-Prosthetic, Inc.Progressive Dynamics MedicalPros-TechProsthetic Center, Inc.Signal Medical CorporationUltralight Prosthetics, Inc.

Medical devices - SafetyAEGIS EnvironmentsAteq CorporationCreative Technology ServicesCritical Signal TechnologiesDanmar Products Inc.Ennew Medical Devices, LLCFreeman Manufacturing CompanyGrant Manufacturing CorporationLake Erie Medical and SurgicalLynn Medical InstrumentsMedi-Nuclear Corp.Michigan InstrumentsMichigan Orthopedic ServicesPlas-Labs, Inc.



Signal Medical CorporationStryker CorporationSurge Medical SolutionsSurgitel

Medical devices - SensorsAdvanced Sensor Technologies, Inc.Bio-Nano Power LLCBiotronic Neural Monitoring SpecialistsCritical Signal TechnologiesCVR Global, Inc.Delphi Medical SystemsECO PHYSICS, INC.Integrated Sensing Systems (ISSYS)Life Science Systems, Inc.MC3, Inc.MedtronicMemsTechMichigan InstrumentsNeuroNexus TechnologiesNext Generation Therapeutics, Inc.Optical DimensionsRapid BioSenseSelective Technologies, Inc.SensoundSomanetics CorporationSonetics Ultrasound, Inc.Terumo Cardiovascular Systems Corp.Ultrasound Medical Devices, Inc.

Medical devices - SurgicalAccord Biomaterials, Inc.Accumed Systems Inc.AI Medical Devices, Inc.Aspen Surgical Products, Inc.ATEK Medical ManufacturingAutocam MedicalAvalon Laboratories LLCBio-Coat Inc.BioProCascade Life SolutionsCovalent Medical, Inc.Di-Coat CorpDoctor’s Orders, Inc.EADevices, Inc.Exponent, Inc.Ferndale Laboratories Inc.Hart EnterprisesHistoSonics, LLCImplants International N.A.INRAD, Inc.Johnson & JohnsonKeystone Product DevelopmentKOA Orthopedics

LVAD Technology, Inc.MedElute, Inc.MedtronicMicro Machine Co.Monteris Medical, Inc.NeuroNexus TechnologiesOmega Surgical Instruments, Inc.Orchid Orthopedic Solutions, LLCOrthopedic Development, Inc.Pioneer Surgical TechnologyPrecision Edge Surgical ProductsStryker CorporationStryker InstrumentsStryker OrthopedicsSurge Medical SolutionsSymmetry JetTerumo Heart, Inc.Thompson Surgical InstrumentsTopspins, Inc.

Medical devices - TherapeuticAcuity Medical, Inc.Adamlab, LLCAlivio CorporationAutocam MedicalAVAcore TechnologiesBio Logic Engineering, Inc.Birchbrook Technologies L.L.C.CFI Medical Solutions (Contour Fabricators, Inc.)ConceivexCovalent Medical, Inc.Creative Technology ServicesDavisMade, Inc.Delphi Medical SystemsEyeLab GroupGrant Manufacturing CorporationHAC of America, Inc.HistoSonics, LLCHygieia, Inc.Implants International N.A.In the Groove, LLCInnovative BioTherapies, IncorporatedLake Erie Medical and SurgicalLVAD Technology, Inc.Lynn Medical InstrumentsMedElute, Inc.MedtronicMonteris Medical, Inc.Nanoderm Therapeutics, Inc.Nephrion, Inc.NuStepOptical Supply

Orthopedic Development, Inc.SciTech DevelopmentSignal Medical CorporationStryker CorporationSurge Medical SolutionsSymmetry JetVigor Equipment, Inc.

Office FurnitureDetroit Technical Equipment CompanyOffice Depot VWR International

Pharmaceuticals & Therapeutics - Animal HealthBayer Health CareGlaxoSmithKlineHorseshoe HerbalsNeogen CorporationPfizer Inc.W.F. Valentine & Co.

Pharmaceuticals & Therapeutics - Biologics & BiosimilarsAdeona PharmaceuticalsAlphaCore PharmaAmgenAursos, Inc.Bayer Health CareBiopolymer InnovationsCerenis Therapeutics Inc.Corium International, Inc.deCODE geneticsEmergent BioSolutionsEsperion Therapeutics, Inc.EXT Lifesciences, Inc.GenentechGenetics Squared, Inc.GlaxoSmithKlineGlyTag LLCImplants International N.A.Innovative BioTherapies, IncorporatedJohnson & JohnsonMuciMed, Inc.NanoBio CorporationNanoVir LLCNephRx CorporationPfizer Inc.ProNAi Therapeutics, Inc.sanofi-aventis USSecretory IgA Inc.ThromgenTolera Therapeutics, Inc.




Pharmaceuticals & Therapeutics - Cell Based Therapies & Regenerative MedicineAastrom Biosciences, Inc.Housey Pharmaceutical Research Laboratories, LLCInnovative BioTherapies, IncorporatedOtoMedicine, Inc.Pfizer Inc.Tolera Therapeutics, Inc.

Pharmaceuticals & Therapeutics - GenericsBayer Health CareCaraco Pharmaceutical Laboratories, Ltd.Corium International, Inc.Eloquest Healthcare Fermical, Inc.Ferndale Laboratories Inc.GlaxoSmithKlineHarvard Drug CompanyJHP PharmaceuticalsPerrigo CompanyQuality Care Products

Pharmaceuticals & Therapeutics - Natural ProductsAlluvium Biosciences Inc.AureoGen Biosciences, Inc.Aursos, Inc.Biopolymer InnovationsDiversified Natural ProductsEcology Health Products, Inc.Eloquest Healthcare EXT Lifesciences, Inc.Graminex, LLCHorseshoe HerbalsMycol Balm Laboratories, Inc.Natural Therapeutics, LLCNeocutisPainex CorporationVenOmix, Inc.zuSyn

Pharmaceuticals & Therapeutics - Nutriceuticals & Alternative MedicinesCerise Nutraceuticals, Inc.Corium International, Inc.Diversified Natural ProductsEcology Health Products, Inc.EXT Lifesciences, Inc.Graminex, LLCHarvard Drug Company

Horseshoe HerbalsJohnson & JohnsonMycol Balm Laboratories, Inc.Natural Therapeutics, LLCNeocutisOtoMedicine, Inc.Painex CorporationSSV Therapeutics, LLC

Pharmaceuticals & Therapeutics - OTCAbbott LaboratoriesBayer Health CareCerise Nutraceuticals, Inc.Corium International, Inc.Ecology Health Products, Inc.Eloquest Healthcare EXT Lifesciences, Inc.Ferndale Laboratories Inc.GlaxoSmithKlineHarvard Drug CompanyJohnson & JohnsonMycol Balm Laboratories, Inc.NanoBio CorporationNanoderm Therapeutics, Inc.Natural Therapeutics, LLCNeocutisOtoMedicine, Inc.Painex CorporationPerrigo CompanyPfizer Inc.Quality Care Products

Pharmaceuticals & Therapeutics - Synthetic Small Molecule21st Century Therapeutics, Inc.Abbott LaboratoriesAdeona PharmaceuticalsAFID Therapeutics, LLCAureoGen Biosciences, Inc.Avidimer Therapeutics, Inc.Bayer Health CareBiomideBiopolymer InnovationsCerenis Therapeutics Inc.deCODE geneticsEmiliemEsperion Therapeutics, Inc.GenentechGenetics Squared, Inc.GlaxoSmithKlineGlyTag LLCHousey Pharmaceutical Research Laboratories, LLC

Jiva Pharma, Inc.Johnson & JohnsonLycera CorporationMeditrina Pharmaceuticals, Inc.Metabolic Solutions Development CompanyMolecular Therapeutics, Inc.NanoBio CorporationNanoderm Therapeutics, Inc.NanoMed Pharmaceuticals, Inc.NanoVir LLCNext Generation Therapeutics, Inc.OtoMedicine, Inc.Pfizer Inc.Phrixus Pharmaceuticals, Inc.QuatRx Pharmaceuticalssanofi-aventis USSciTech DevelopmentSSV Therapeutics, LLCTakeda Pharmaceuticals North America, Inc.TCH Pharmaceuticals, Inc.Trilithon Pharma, LLCVelcura Therapeutics, Inc.zuSyn

Pharmaceuticals & Therapeutics - VaccinesEmergent BioSolutionssanofi-aventis US

Procurement ServicesSingle Source Procurement, LLC

Public RelationsLindsay Exhibit Group, Inc.PR NewswireTeresa M. Arnold & Associates

Real EstateBluestone Realty AdvisorsSkyline Property Group, Inc.

Research Tools - instruments & EquipmentAccuri CytometersAdvanced Photonix Inc.ASI Instruments, Inc.Aspen Surgical Products, Inc.Atodyne Technologies LLCBecton Dickinson - Difco LaboratoriesBioFlow Technology, Inc.BioLumix, Inc.Biophotonic Solutions, Inc.Biotronic Neural Monitoring SpecialistsClean Air Technology



Custom Biogenic SystemsData Integrated Scientific SystemsDiagnostic Instruments Inc.Digilab Genomic SolutionsDNADNB LLCECO PHYSICS, INC.FlowTech CorporationGene CodesGeneGo, Inc.Genomatix Software, Inc.Handy Lab, Inc.Incept BioSystemsIntegrated Sensing Systems (ISSYS)Jade ScientificLife Science Systems, IncMedArray Inc.Medical Accessories & Research CorporationMedi-Nuclear Corp.Pall Corporation - Life SciencesPBS BiotechPhadia USPointe Scientific, Inc.Richard-Allan ScientificRigaku Innovative TechnologiesRJL Systems, Inc.Roush Life SciencesSterling DiagnosticsSystems SpecialtiesTerumo Cardiovascular Systems Corp.Thorn Smith Laboratories

Research Tools - lab FurnishingsClean Air TechnologyJade Scientific

Research Tools - Reagents & Materials3D BiomatrixAccuri CytometersApoLife, Inc.Assay Designs, Inc.Asterand, Inc.Becton Dickinson - Difco LaboratoriesBerry & Associates, Inc.Biodiscovery, LLCBioLumix, Inc.Biosol, Ltd.BiotectixCayman Chemical CompanyCNVGenes LLCCovalent Medical, Inc.Detroit R & D, Inc.Digilab Genomic SolutionsGiri Diagnostics LLC

GlyTag LLCHandy Lab, Inc.HealthCure, LLCImplants International N.A.Incept BioSystemsInnovative Research Inc.Intermediary Biochemicals, LLCInvirion, Inc.Jade ScientificJV BiolabsLumigen, Inc.Luminos LLCMichigan Antibody Technology Center - Center of Technology ExcellenceMichigan Diagnostics LLCMolecular Innovations Inc.NanoMed Pharmaceuticals, Inc.Neogen CorporationNitrate Elimination Company, Inc.Originus, Inc.Oxford Biomedical Research, Inc.Pall Corporation - Life SciencesPhadia USPhycoTechPointe Scientific, Inc.Proteos, Inc.Richard-Allan ScientificRockwell Medical Technologies, Inc.Rubicon Genomics, Inc.Sequenom Center for Molecular MedicineSoloHill Engineering, Inc.Sterling DiagnosticsSystems SpecialtiesThorn Smith LaboratoriesXG Sciences, Inc.

Research Tools - Testing & KitsApoLife, Inc.Assay Designs, Inc.Becton Dickinson - Difco LaboratoriesBioLumix, Inc.Cayman Chemical CompanyCNVGenes LLCDetroit R & D, Inc.Digilab Genomic SolutionsGiri Diagnostics LLCHandy Lab, Inc.Lumigen, Inc.Mainline Technologies InternationalMichigan Diagnostics LLCMicromyx, LLCMolecular Innovations Inc.Neogen CorporationNextGen Sciences, Inc.

Nitrate Elimination Company, Inc.Originus, Inc.Oxford Biomedical Research, Inc.Phadia USPhycoTechPointe Scientific, Inc.Richard-Allan ScientificRubicon Genomics, Inc.Sequenom Center for Molecular MedicineSterling DiagnosticsThorn Smith Laboratories

SoftwareArivium, Inc.Fullscope, Inc.MasterControl, Inc.Plex SystemsProPharma Group

Staffing & RecruitingSOI HR SolutionsThe Point ServicesTrialon Corporation

Strategy/PlanningApjohn Group, LLCAptuit Consulting, Inc.Biotechnology Business Consultants (BBC)Caladium ConsultingCollet Consulting, LLCGlobal Strategic Connections, LLCLindsay Exhibit Group, Inc.Newport Consulting GroupSOI HR SolutionsTEDCo - Technology Enterprise Development Co., Inc.Teresa M. Arnold & AssociatesWise BioStrategies LLC

SupplierDetroit Technical Equipment CompanyFarnell Equipment CompanyLinde LLCOffice Depot O’Mara ProductsSingle Source Procurement, LLCVWR International

Technical WritingAptuit Consulting, IncBiotechnology Business Consultants (BBC)ProPharma Group



University/Institution/Hospital – Academic/EducationCentral Michigan University - Office of Research and Sponsored ProgramsCentral Michigan University - Research CorporationGrand Valley State UniversityInstitute for Preventive Sports MedicineLenawee Intermediate School DistrictMichigan Molecular InstituteMichigan State University - Institute for Health Care StudiesMichigan State University - MSU TechnologiesMichigan State University – Office of Research & Graduate Studies Michigan State University - Product Center for Agriculture and Natural ResourcesMichigan Technological University - Office of Technology and Economic DevelopmentOakland UniversityThe MRI Institute for Biomedical Research ImagingUniversity of Michigan - Biomedical EngineeringUniversity of Michigan - Coulter Translational Research Partnership ProgramUniversity of Michigan - Life Sciences InstituteUniversity of Michigan - Medical Innovation CenterUniversity of Michigan - Michigan Center for Oral HealthUniversity of Michigan - Michigan Institute for Clinical Health ResearchUniversity of Michigan - Michigan Nanotech-nology Institute for Medicine and Biological SciencesUniversity of Michigan – Office of Vice- President for Research University of Michigan - Technology Transfer OfficeWayne State University - Technology CommercializationWayne State University Applied Genomic Technologies - Center for Technology Excellence

University/institution/hospital - Clinical/HospitalBeaumont HospitalsBorgess Research InstituteHenry Ford Health SystemInstitute for Health Care StudiesInstitute for Health StudiesInstitute for Preventive Sports MedicineKarmanos Cancer Institute

The MRI Insititute for Biomedical Research ImagingUniversity of Michigan - Medical Innovation CenterUniversity of Michigan - Michigan Center for Oral Health University of Michigan - Michigan Institute for Clinical Health ResearchUniversity of Michigan - Michigan Nanotechnology Institute for Medicine and Biological SciencesWayne State University Applied Genomic Technologies - Center for Technology Excellence

University/institution/hospital - Contract WorkAltarum InstituteBeaumont HospitalsBiosciences Research & Commercialization Center - Center for Technology ExcellenceBorgess Research InstituteInstitute for Health StudiesMBI InternationalMichigan Animal Model Consortium - Center for Technology ExcellenceMichigan Biological Imaging Center - Center for Technology ExcellenceMichigan Center for Biological Information - Center for Technology ExcellenceMichigan Molecular InstituteMichigan State University - Michigan Center for Structural Biology - Center for Technology ExcellenceUniversity of Michigan - Michigan Institute for Clinical Health ResearchUniversity of Michigan - Michigan Proteome Consortium - Center for Technology ExcellenceWayne State University Applied Genomic Technologies - Center for Technology Excellence

University/institution/hospital - PrivateAltarum InstituteBeaumont HospitalsBorgess Research InstituteHenry Ford Health SystemInstitute for Health StudiesKarmanos Cancer InstituteMichigan Animal Model Consortium - Center for Technology ExcellenceMichigan Antibody Technologies Center - Center For Technology ExcellenceMichigan Molecular InstituteThe MRI Institute for Biomedical Research ImagingVan Andel Institute

University/institution/hospital - PublicBiosciences Research & Commercialization Center - Center for Technology ExcellenceCentral Michigan University - Office of Re-search and Sponsored ProgramsCentral Michigan University - Research CorporationGrand Valley State UniversityMichigan Biological Imaging Center - Center for Technology ExcellenceMichigan Center for Biological Information - Center for Technology ExcellenceMichigan High Throughput Screening Center - Center for Technology ExcellenceMichigan State University - Michigan Center for Structural Biology - Center for Technology ExcellenceMichigan State University - MSU TechnologiesMichigan State University – Office of Research & Graduate Studies Michigan State University - Product Center for Agriculture and Natural ResourcesMichigan Technological University Office of Technology and Economic DevelopmentMichigan Universities Commercialization Initiative (MUCI)Oakland UniversityUniversity of Michigan - Biomedical EngineeringUniversity of Michigan - Coulter Translational Research Partnership ProgramUniversity of Michigan - Life Sciences InstituteUniversity of Michigan - Medical Innovation CenterUniversity of Michigan - Michigan Center for Oral HealthUniversity of Michigan - Michigan Institute for Clinical Health ResearchUniversity of Michigan - Michigan Nanotechnology Institute for Medicine and Biological SciencesUniversity of Michigan - Michigan Proteome Consortium - Center for Technology ExcellenceUniversity of Michigan – Office of Vice- President for Research University of Michigan - Technology Transfer OfficeWayne State University - Technology CommercializationWayne State University Applied Genomic Technologies - Center for Technology Excellence




University/institution/hospital - ResearchAltarum InstituteBeaumont HospitalsBiosciences Research & Commercialization Center - Center for Technology ExcellenceBorgess Research InstituteCentral Michigan University - Office of Research and Sponsored ProgramsCentral Michigan University - Research CorporationGrand Valley State UniversityHenry Ford Health SystemInstitute for Health StudiesInstitute for Preventive Sports MedicineKarmanos Cancer InstituteMBI InternationalMichigan Animal Model Consortium - Center for Technology ExcellenceMichigan Biological Imaging Center - Center for Technology ExcellenceMichigan Center for Biological Information - Center for Technology ExcellenceMichigan Molecular InstituteMichigan State University - Michigan Center for Structural Biology - Center for Technology ExcellenceMichigan State University - MSU TechnologiesMichigan State University – Office of Research & Graduate Studies Michigan State University - Product Center for Agriculture and Natural ResourcesMichigan Technological University - Office of Technology and Economic DevelopmentMichigan Universities Commercialization Initiative (MUCI)Oakland UniversityQuantum LaboratoriesThe MRI Institute for Biomedical Research ImagingUniversity of Michigan - Biomedical EngineeringUniversity of Michigan - Coulter Translational Research Partnership ProgramUniversity of Michigan - Life Sciences InstituteUniversity of Michigan - Medical Innovation CenterUniversity of Michigan - Michigan Center for Oral HealthUniversity of Michigan - Michigan Institute for Clinical Health ResearchUniversity of Michigan - Michigan Nanotechnology Institute for Medicine and Biological SciencesUniversity of Michigan - Michigan Proteome Consortium - Center for Technology Excellence

University of Michigan - Office of Vice President for Research University of Michigan - Technology Transfer OfficeVan Andel InstituteWayne State University - Technology CommercializationWayne State University Applied Genomic Technologies - Center for Technology Excellence

University/institution/hospital-Tech TransferBeaumont Commercialization CenterBiosciences Research & Commercialization Center - Center for Technology ExcellenceBorgess Research InstituteCentral Michigan University - Office of Research and Sponsored ProgramsCentral Michigan University - Research CorporationGrand Valley State UniversityGreat Lakes Drug Development, Inc.Michigan Technological University Office of Technology and Economic DevelopmentMichigan Universities Commercialization Initiative (MUCI)Michigan State University - MSU TechnologiesMichigan State University - Product Center for Agriculture and Natural ResourcesOakland UniversityUniversity of Michigan - Medical Innovation CenterUniversity of Michigan - Technology Transfer OfficeVan Andel InstituteWayne State University - Technology Commercialization

Venture & Angel CapitalApjohn Group, LLCArboretum VenturesArdesta, LLCCapital Advisors Group, Inc. Great Lakes Angels, Inc.Michigan Life Ventures, LLCMicroDose Life Sciences, LLC



AlleganDrug & Laboratory Disposal, Inc.Perrigo CompanyTeam Pharmaceutical Inc.

BenzieAlivio CorporationInvirion, Inc.Thorn Smith Laboratories

BerrienGeneGo, Inc.Horseshoe HerbalsPhycoTechSlaughter Instrument Co.Vigor Equipment, Inc.

CalhounCity of Marshall Economic DevelopmentKellogg CompanyProgressive Dynamics Medical

ChippewaEcology Health Products, Inc.Precision Edge Surgical Products

ClintonMichigan Corn Growers Association/Corn Marketing Program of Michigan

Eaton Michigan Primary Care Association

GeneseeBremer Prosthetics, Inc.CFI Medical Solutions (Contour Fabricators, Inc.)DavisMade, Inc.Motion Resources, Styker OrthopedicOmega Surgical Instruments, Inc.Selective Technologies, Inc.TEDCo - Technology Enterprise Development Co., Inc.

Grand TraverseCerise Nutraceuticals, Inc.Global Remediation Technologies IncorporatedThe Point ServicesThompson Surgical InstrumentsTwin Bay Medical, Inc.Versus Technology, Incorporated

HillsdaleW.F. Valentine & Co.

HoughtonKeweenaw Nanoscience CenterMichigan Technological University Office of Technology and Economic DevelopmentNitrate Elimination Company, Inc.Tech Initiatives Inc.

HuronThumb Oilseed Producers

InghamAFID Therapeutics Inc.AI Medical Devices, Inc.Antel BioSystems, Inc.AquaBiochip, LLCBiophotonic Solutions, Inc.Biopolymer InnovationsDraths Industries, LLCEcoSynthetixEmerald BioAgriculture Corporation / Auxein CorporationEmergent BioSolutionsFraunhofer USA CCLGEMA, LLCInstitute for Health StudiesIntermediary Biochemicals, LLCLEC Tech, Inc.MBI InternationalMcClinchey Histology Lab, Inc.Merit Laboratories, Inc.MetagenX, LLCMichigan Agri-Business AssociationMichigan Association of Health PlansMichigan Biomass Energy ProgramMichigan Center for Structural Biology - Center for Technology ExcellenceMichigan Chemistry CouncilMichigan Economic Development CorporationMichigan Health & Hospital AssociationMichigan Health CouncilMichigan Medical Dental AssociationMichigan Nurses AssociationMichigan Osteopathic AssociationMichigan State Medical SocietyMichigan State University, Office of Research and Graduate StudiesMSU Technologies, Michigan State UniversityNeogen CorporationOrchid Orthopedic Solutions, LLCPBS BiotechPlas-Labs, Inc.Product Center for Agriculture and Natural Resources, Michigan State UniversityProsthetic Center, Inc.Rapid BioSense

Symmetry JetToxicogenomic Informatics and Solutions, LLCWorking Bugs, LLCXG Sciences, Inc.

IoniaConceivex

IsabellaBauer BioMedical, LLCBio-Nano Power LLCCentral Michigan University - Office of Research and Sponsored ProgramsCentral Michigan University - Research CorporationDendritic Nanotechnologies, Inc.

JacksonCoy Laboratory Products Inc.Midbrook, Inc.Sparton Medical Systems TransPharm Preclinical Solutions, LLC

KalamazooADMETRxApjohn Group, LLCArmune BioScience, Inc.AureoGen Biosciences, Inc.Aursos, Inc.Axenic Dental, Inc.AzoRx, Inc.BioMedPharmIS, Ltd.Biosciences Research & Commercialization Center - Center for Technology ExcellenceBiosciences Research and Commercialization Center at Western Michigan UniversityBioSTAT Consultants, Inc.Borgess Research InstituteBridge Organics Co.CeeTox, Inc.Charles RiverContented Hearts, Inc.CRB Consulting EngineersCSM GroupEADevices, Inc.EmiliemEnnew Medical Devices, LLCEurofins Avtech Laboratories, Inc.FlowTech CorporationGenemarkers LLCGlobal Clinical ConnectionsHAC of America, Inc.Hanger Prosthetics & OrthodicsHistoSonics, LLC”Honigman Miller Schwartz and Cohn LLP

L IST ING By COUNTIES



Innovative Analytics Inc.J. Rettenmaier, USAJasper Clinical Research & Development, Inc.Kalexsyn, Inc.KAR Bioanalytical, Inc.Keystone Product DevelopmentKomodo Pharmaceutical Services, LLCMedElute, Inc.Metabolic Solutions Development CompanyMichigan Biological Imaging Center - Center for Technology ExcellenceMichigan Business ReviewMichigan High Throughput Screening Center - Center of Technology ExcellenceMicro Machine Co.Micromyx, LLCMonteris Medical, Inc.MuciMed, Inc.NanoMed Pharmaceuticals, Inc.NanoVir LLC NephRx CorporationOrthopedic Development, Inc.OtoMedicine, Inc.Pfizer Inc.Phadia USPharmMor Consulting, LLCPharmOptima, LLCProNAi Therapeutics, Inc.ProPharma GroupProteos, Inc.Richard-Allan ScientificS & J LaboratoriesSingle Source Procurement, LLCSouthwest Michigan FirstSouthwest Michigan Innovation CenterStryker CorporationStryker InstrumentsTolera Therapeutics, Inc.Trilithon Pharma, LLCVenOmix, Inc.zuSyn

KentAccess Business GroupArivium, Inc.Aspen Surgical Products, Inc.ATEK Medical ManufacturingAutocam MedicalAvalon Laboratories LLCBio-Chem Laboratories, Inc.Cascade Life SolutionsClinXusCorium International, Inc.Davis Dental LabsElkins Innovations, Inc.Ernst & Young LLP

Gerontology NetworkGrand River Aseptic Pharmaceutical Packaging, Inc.Grand Valley State UniversityHart EnterprisesHaviland EnterprisesINRAD, Inc.Juvenile Diabetes Research Foundation - West MichiganMarketLabMedbio, Inc.MedtronicMichigan Animal Model Consortium - Center for Technology ExcellenceMichigan Antibody Technology Center - Center of Technology ExcellenceMichigan InstrumentsMichigan Small Business & Technology Development CenterMidwest Cleanroom Associates, Inc.O’Mara ProductsOptical SupplyPinnacle Insurance PartnersPrice, Heneveld, Cooper, DeWitt & LittonRose TechnologiesSequenom Center for Molecular MedicineSkytronSurge Medical SolutionsThe Right Place, Inc.Van Andel InstituteVarnum, Riddering, Schmidt & HowlettWarner Norcross & Judd LLPWest Michigan Regional LaboratoryWest Michigan Science and Technology InitiativeXB TransMed Solutions, LLC

LenaweeBio-lab, Inc., A Chemtura CompanyLenawee Intermediate School DistrictUckele Health and NutritionWacker Chemical Corporation

LivingstonAcuity Medical, Inc.BioFlow Technology, IncBruce Johnson Service Co., Inc.deCODE geneticsGreat Lakes Drug Development, Inc.International Partnership for Critical Markers of Disease (CMOD)

Macomb21st Century Therapeutics, Inc.ASI Instruments, Inc.

Birchbrook Technologies L.L.C.College Park Industries Custom Biogenic Systems Mt. Clemens Orthopaedic Appliances, Inc.PTI Engineered Plastics, Inc.RJL Systems, Inc.Sterling Diagnostics

ManisteeDer-Balian Inc.

MarquettePioneer Surgical Technology

Mason Diversified Natural Products

MidlandAEGIS EnvironmentsCaltech Industries, Inc.Crissman Toxicologic Pathology, LLCDendritech, Inc.GANTEC, Inc.Life Science Systems, Inc.Michigan Molecular InstituteMidMichigan Innovation CenterPathology Experts, LLCThe Dow Chemical Company

MissaukeeBlueWare, Inc.

MonroeLake Erie Medical and SurgicalQuality Care ProductsTeresa M. Arnold & Associates

MuskegonBayer CropScienceBurdick & JacksonNorthern Biomedical Research, Inc.Tower Laboratories Montague

NewaygoGerber Product Company

OaklandAbsolute Analytical, Inc.Adamlab, LLCAdvanced X-Ray Technology, Inc.American Dental Technologies, Inc.American Diabetes AssociationAmerican Society of EmployersAngott Medical Products, LLCAP Bio-Consulting LLC




Oakland continued...

Automation AlleyAxsys Technologies, Inc.Beaumont Commercialization CenterBeaumont HospitalsBeaumont Services Company LLCBecker OrthopedicBio-Coat Inc.Biotech Clinical LaboratoriesBoro Pharm, LLCBrooks KushmanCell Culture Characterization ServicesChubb Group of Insurance CompaniesCNVGenes LLCCornerstone Benefits, LLCCritical Signal TechnologiesDelphi Medical SystemsDetroit Technical Equipment CompanyDiagnostic Instruments Inc.Di-Coat CorpDNADNB LLCDoeren MayhewEarly Warning Healthcare InstituteEloquest Healthcare Exponent, Inc.EXT Lifesciences, Inc.Farnell Equipment CompanyFermical, Inc.Ferndale Laboratories Inc.Gifford, Krass, Sprinkle, Anderson & Citkowski, P.C.Giri Diagnostics LLCGlobal Strategic Connections, LLCGlyTag LLCGreat Lakes Angels, Inc.Harness, Dickey & Pierce, P.L.C.HealthCure, LLCHealthtreat, Inc.Housey Pharmaceutical Research Laboratories, LLCiDesign Solutions, LLCInnovative Cell TechnologyInnovative Research Inc.JHP PharmaceuticalsJohnson & JohnsonJuvenile Diabetes Research Foundation - Metro Detroit & SE MichiganKOA OrthopedicsLumigen, Inc.Lynn Medical InstrumentsMaximax International Inc.Medi-Nuclear Corp.Michigan Citizens for Stem Cell Research and Cures (MCSCRC)Michigan Diagnostics LLCMicrobiological Associates, Inc.

Microcide, Inc.MicroDose Life Sciences, LLCMiller, Canfield, Paddock & Stone, P.L.C.Molecular Innovations Inc.Monal, Inc./Monal Labs Newport Consulting GroupNorthwest Orthotics-Prosthetic, Inc.Oakland County Planning & Economic Devel-opmentOakland UniversityOptical DimensionsOptim Oxford Biomedical Research, Inc.Phillips Plastics Corporation Plex SystemsPR NewswirePros-TechQuantum LaboratoriesQuest Diagnostics IncorporatedQuest Research InstituteRADAR Medical Systems LLCRader, Fishman & Grauer PLLCRegulatory Affairs Associates, LLCRG Medical DiagnosticsRigaku Innovative TechnologiesRockwell Medical Technologies, Inc.RxDispense, Inc.SANDAB GroupSkyline Property Group, Inc.Somanetics CorporationSynergy Group, Inc.Systems SpecialtiesTrialon CorporationTroy PolymersWestern Slope LaboratoryWilliams Syndrome AssociationYourSurgery.com

OntonagonSubTerra LLC

OttawaAir Force Inc.Doctor’s Orders, Inc.Garrison Dental SolutionsMead Johnson NutritionalsMedical Accessories & Research CorporationSPI PharmaVertellus Health and Specialty Products, LLCWelch Laboratories, Inc.

SaginawAgriumAmigo Mobility InternationalDuPeron Medical SystemsField Neuroscience Institute

Graminex, LLCIn the Groove, LLCMichigan Soybean Promotion CommitteeMycol Balm Laboratories, Inc.Orchard Unique

St. ClairBioProSignal Medical Corporation

St. JosephAbbott LaboratoriesFreeman Manufacturing Company

Van BurenAlbemarle CorporationMPI Research

Washtenaw3D BiomatrixAAPharmaSyn LLCAastrom Biosciences, Inc.Accord Biomaterials, Inc.Accumed Systems Inc.Accuri Cytometers Adeona PharmaceuticalsAdvanced Photonix Inc.AIS ConsultingAkervall TechnologiesAlluvium Biosciences Inc.AlphaCore PharmaAltarum InstituteAmerican Society for MicrobiologyAnn Arbor Clinical ResearchAnn Arbor SPARKArbor Preclinical & Consulting, LLCArbor Research Collaborative for HealthArboretum VenturesArdesta, LLCAssay Designs, Inc.Atodyne Technologies LLCAVAcore TechnologiesAvicenna Medical Systems, Inc.Avidimer Therapeutics, Inc.Bank of Ann ArborBerry & Associates, Inc.Better Rehab, LLCBio Logic Engineering, Inc.Biodiscovery, LLCBioLumix, IncBiomedical Diagnostics, LLCBioMedware Inc.BioPharma Data Services Biosol, Ltd.Biotechnology Business Consultants (BBC)



BiotectixBiotronic Neural Monitoring SpecialistsBluestone Realty AdvisorsBrinks, Hofer, Gilson & LioneBrown & Brown of DetroitButzel LongCaladium ConsultingCalibrate, Inc.Cascade Hemophilia ConsortiumCayman Chemical CompanyCentromine, Inc.Cerenis Therapeutics Inc.Christian Roux Ltd.Cielo MedSolutionsClinSite, Inc.Collet Consulting, LLCCompendia BioscienceCoulter Translational Research Partnership Program, University of MichiganCovalent Medical, Inc.Critech Research, Inc.Cutting Image Histology, LLCCybernet MedicalDanmar Products Inc.Data Integrated Scientific SystemsDBA Analytical (an NSF International Com-pany)Ddots, Inc.DermanautDigilab Genomic SolutionsDNA Software, Inc.ECO PHYSICS, INC.Essen InstrumentsEyeLab GroupField Consulting Services, Inc.Fulcrum Pharma Developments, Inc.GE Medical Systems Information TechnologyGene Codes Genetics Squared, Inc.GeneVivo, LLCGenomatix Software, Inc.Gift of Life MichiganGoteborgBio - BRGGreat Lakes Entrepreneur’s QuestHamztec LLCHandy Lab, Inc.HealthMedia, Inc.Hygieia, Inc.Hylant Groupi3 STATPROBE, Inc.Implants International N.A.Incept BioSystems Innovative BioTherapies, IncorporatedInstitute for Preventive Sports Medicine

Integrated Nonclinical Development Solutions, Inc.Integrated Sensing Systems (ISSYS)International Discovery Sourcing Consultants LLCINVIA Medical Imaging SolutionsJiva Pharma, Inc.JV BiolabsKendle InternationalKestrel Consultants, Inc.Koppert Biological Systems, Inc.Lead Biopharma Consulting, LLCLindsay Exhibit Group, Inc.Luminos LLCMager Scientific Inc.Mainline Technologies International MayaterialsMC3, Inc.MedArray Inc.Medical Imaging Resources, Inc.Medical Innovation Center, University of MichiganMedImage, Inc.Meditrina Pharmaceuticals, Inc.MERS, LLCMichBioMichigan Center for Biological Information - Center for Technology Excellence Michigan Center for Oral HealthMichigan Institute for Clinical Health ResearchMichigan Israel Business BridgeMichigan Life Ventures, LLCMichigan Nanotechnology Institute for Medi-cine and Biological SciencesMichigan Proteome Consortium - Center for Technology ExcellenceMichigan Research InstituteMichigan Science Teachers AssociationMichigan Technology and Research Institute, LLCMichigan Universities Commercialization Initiative (MUCI)Michigan Venture Capital AssociationMIR Preclinical Services (Molecular Imaging Research)Molecular Therapeutics, Inc.NanoBio CorporationNanoderm Therapeutics, Inc.National Center for Manufacturing SciencesNational Kidney Foundation of MichiganNatural Therapeutics, LLCNephrion, Inc.NeuroNexus TechnologiesNext Generation Therapeutics, Inc.NextGen Sciences, Inc.

Norwind-CortezNuStepNymirumOcuSciences, Inc.Ophthigenics LLCOriginus, Inc.Pall Corporation - Life SciencesPhrixus Pharmaceuticals, Inc.Pixel Velocity Inc.POLY BioinformaticsProtomaticQuatRx PharmaceuticalsRTI Health SolutionsRubicon Genomics, Inc.Saline Lectronics, Inc.ScarPrev PharmaceuticalsScreenTrack Secretory IgA Inc.Sentry Medical TechnologiesSiemens Ultrasound DivisionSmith Haughey Rice & RoeggeSOI HR SolutionsSoloHill Engineering, Inc.Sonetics Ultrasound, Inc.SSV Therapeutics, LLCSurgitelSwitchbackTCF National BankTCH Pharmaceuticals, Inc.TERRE Clinical Research Services, Inc.Terumo Cardiovascular Systems Corp.Terumo Heart, Inc.Thomson HealthcareThreefold Sensors, LLCThromgenTopspins, Inc.Torrey Path LLCTSRL, Inc.Ultrasound Medical Devices, Inc.United BioSource CorporationUniversity of Michigan - Biomedical EngineeringUniversity of Michigan - Life Sciences InstituteUniversity of Michigan - Office of Vice President for ResearchUniversity of Michigan - Technology Transfer OfficeVelcura Therapeutics, Inc.Velesco Pharma ServicesVetGen, LLCVWR InternationalWarde Medical LaboratoryWise BioStrategies LLCXoran Technologies, Inc.



WayneAdvanced Sensor Technologies, Inc.ApoLife, Inc.Ash StevensAsterand, Inc.Ateq CorporationBecton Dickinson - Difco LaboratoriesBiomideBrenner Orthotic and Prosthetic LabsCanadian Consulate GeneralCaraco Pharmaceutical Laboratories, Ltd.CardiArcClean Air TechnologyClinical Ligand Assay SocietyCreative Technology ServicesCVR Global, Inc.Detroit R & D, Inc.Dykema, PLLCEliason ConsultingEsperion Therapeutics, Inc.Fullscope, Inc.Grant Manufacturing CorporationHarvard Drug CompanyHenry Ford Health SystemInland Waters Pollution ControlJade ScientificKarmanos Cancer InstituteLaw Offices of Gary Kendra, PCLVAD Technology, Inc.Lycera CorporationMcKesson Pharmacy SystemsMemsTechMichigan Orthopedic ServicesMMS Holdings Inc.M-VisionNeocutisNEXT MobilityPainex CorporationParagon Laboratories, Inc.Pharmacision LLCPointe Scientific, Inc.PVS Chemicals, Inc.Riverside OrganicsRoche Biomedical LabsRoush Life SciencesSciTech DevelopmentSensoundShanghai Bio CorporationShrader Analytical and Consulting Laboratories, Inc.Stryker OrthopedicsTechTown

The MRI Insititute for Biomedical Research ImagingUltralight Prosthetics, Inc.Virotech Co., Inc.Vortech PharmaceuticalsWayne State University - Technology CommercializationWayne State University Applied Genomic Technologies - Center for Technology Excellence


Strategic Sale Advisory

UNMATCHED ACCESS. UNCOMPROMISING RESULTS.

In the life sciences sector, it takes deep industry access and a highly-disciplined approach to generatepremium value in a transaction. At P&M Corporate Finance, our expertise in the medical device,diagnostics, and healthcare sectors, combined with our expansive industry relationships, affords us aunique perspective in the industry. Whether your goal is to sell, execute an acquisition strategy, or obtain capital, you can rely on our experienced professionals.

Contact our Life Sciences team today to find out how we can make a difference in your transaction.

Bryan Hughes • 248.223.3678 • [email protected] Gilbert • 248.223.3326 • [email protected]

Detroit • Chicago • Cleveland • pmcf.com

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PMCF Life Sciences 8.75x11.25 Color bleed.qxp 3/11/2009 9:06 AM Page 1

Me Grow My business.wouLD HeLPits educated and innovative people would give companies like mine the resources to create and discover new medicines to treat life-threatening human diseases. its county would initiate economic development programs to help companies like ours attract and retain outstanding research scientists to keep our businesses growing. My ideal City would keep me connected to a network of more than 2,000 other high-tech research and development facilities in the same county. but my ideal City is not just ideal, it’s real, and can be found in oakland County, Michigan.

Find out more about your Ideal City at globaloakland.comGerard M. Housey, M.D., Ph.D.President and CEO Housey Pharmaceutical Research Laboratories Southfield, Michigan

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BioMatters - Spring 2009