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Biomaterials andMedical Devices

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Contents

Nanomaterials ......................................................3

Complex Tissue & Organs....................................8

Engineering Cells ................................................11

Biotechnology ....................................................13

Materials Science ................................................15

Drug Delivery ....................................................21

Biomaterials Education........................................22

Medical Devices..................................................26

Industry Applications ..........................................29

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3

Nanomaterials

For more information and complete contents, visit www.crcpress.com

New!

The Nano-biotechnologyHandbookEdited by

Yubing XieUniversity at Albany, College ofNanoscale Science andEngineering, New York, USA

Offering a uniquely thorough overview ofnanobiotechnology and its place in today’s advance-ments in applied science, this comprehensive surveycombines contributions from physics, bioorganic andbioinorganic chemistry, molecular and cellular biolo-gy, materials science, and medicine as well as frommechanical, electrical, chemical, and biomedical engi-neering to address the full scope of current and futuredevelopments. World-class experts discuss the role ofnanobiotechnology in bioanalysis, biomolecular nan-otechnology, biosensors, and the use of nanotechnol-ogy in biofuels. Focusing on major research trends,the book highlights the importance of nanobiotech-nology to a range of medical applications such asstem cell technology and tissue engineering, drugdevelopment and delivery, imaging, diagnostics, andtherapeutics.

• Provides a thoroughly comprehensive overviewof all major aspects of nanobiotechnology

• Discusses nanofabrication techniques and applications of nanotechnology for bioprocessing

• Covers nanotoxicity, responsible nanotechnology, and educational and workforce development

• Offers extensive references within each chapterto facilitate further study

• Includes a companion CD that contains all figures in the book

Selected Contents:

Biomimetic Nanotechnology. Nanobiofabrication.Nanobioprocessing. Biomolecular and CellularManipulation and Detection. BiomedicalNanotechnology. Nanobiotechnology Impacts.Index.

Catalog no. K11758, November 2012, 692 pp.ISBN: 978-1-4398-3869-3, $169.95 / £108.00Also available as an eBook

New!

NanotechnologyThe Whole StoryBen Rogers and Jesse AdamsNevadaNano, USA

Sumita PennathurUniversity of California, SantaBarbara, USA

This book communicates, in easy-to-understand lan-guage, the sometimes tough-to-understand conceptsof nanotechnology, providing a comprehensive refer-ence for technically interested/trained laymen in thegeneral public who want to learn more about this rev-olutionary, high-impact field of technology. Theamount and level of math used in the pedagogy ofthe text has been minimized to cater to a generalaudience. The book includes behind-the-scenes sto-ries of Nobel-prize-winning scientists—complete witheureka moments—as well as back-of-the-envelopecalculations showing the real numbers of nanotech-nology. Thematic figures have been created to piquethe interest and guide readers.

• Delves into the history of nanotechnology, withspecial emphasis on key personalities and earlymilestones

• Discusses the effects this new industry couldhave on human life, careers, education, and theenvironment

• Covers scaling laws, giving us intuition aboutthe physical ramifications of miniaturization

• Tackles the eight main disciplines: nanomaterials, nanomechanics, nanoelectronics,nanoscale heat transfer, nanophotonics,nanoscale fluid mechanics, nanobiotechnology,and nanomedicine

• Uses real-world applications to teach key concepts

Selected Contents:

Big Picture of the Small World. Introduction toMiniaturization. Introduction to Nanoscale Physics.Nanomaterials. Nanomechanics. Nanophotonics.Nanoscale Fluid Mechanics. Nanobiotechnology.Nanomedicine.

Catalog no. K14290, March 2013, 395 pp.ISBN: 978-1-4398-9780-5, $69.95 / £44.99Also available as an eBook




4 Save when you order online at www.crcpress.com

Nanomaterials

Forthcoming!

Nano-biomaterialsDevelopment andApplicationsEdited by

Dong Kee YiKyungwon University, Gyeonggi-do, Republic of Korea

Georgia C. Papaefthymiou-DavisVillanova University, Pennsylvania, USA

This book provides new findings and applications innanoscale material preparation and multidisciplinarybionanomaterials research. It presents 12 chapters con-tributed by an international team of investigators, whoare actively engaged in cutting-edge research in theirrespective disciplines. The book is divided into fourparts, the first covering nanomaterial preparation, char-acterization, and applications in nanobiotechnology,the second covering the assembly of biomolecules toform soft nanobuilding blocks, the third covering nano-material application in biomechanics and micro scalefabrication process, and the fourth covering nanomate-rial applications in eco-research and cytotoxicity.

• Offers readers a better appreciation of theimportance of this interdisciplinary field tobiotechnology, biomedicine, and environmentalremediation

• Discusses magnetic nanoparticles, bioimaging,biomedical applications, cancer therapy, tissueengineering, and more

Selected Contents:

Nanomaterial in Nanobiotechnologies:Preparation, Characterization and Applications.Bio-inspired Magnetic Nanoparticles. Nanoparticlesfor Bioimaging. Biomedical Applications of DendrimerPorphyrin or Phthalocyanine. Polymeric Nanoparticlesin Cancer Therapy. Fullerene and Carbon NanotubeBioconjugates. Biocatalytic Nanosystems. SoftNanobuilding Blocks: New Types of SoftNanomaterial Preparation Using Biomolecules.Engineered Biomolecules as a Nanomaterial. DNATiles as Nanostructuring Building Blocks: Fabricationsand Applications. Nanomaterials and BioMEMS:Nano and Nicro Scale Hybridization of Materialsand Applications. Microfluidic based PolymerScaffold Design for Tissue Engineering. Fabrication ofMobile Hybrid Microswimmers usingMicro/Nanoparticles and Bacterial Flagella. Nano-Toxicity Study and Applications in Eco-BioSystems. Environmental Applications ofNanomaterials. Nanoparticle toxicity: recommenda-tion for NanoMedicine.

Catalog no. K13550, August 2013, c. 488 pp.ISBN: 978-1-4398-7641-1, $149.95 / £99.00Also available as an eBook

Forthcoming!

BiosensorsBased onNanomaterialsand NanodevicesEdited by

Jun LiKansas State University,Manhattan, USA

Nianqiang WuWest Virginia University, Morgantown, USA

This book provides readers with a quick overview ofthe exciting potential and critical challenges of emerg-ing biosensors based on nanomaterials and nanode-vices for future health monitoring, disease diagnosis,and therapeutic treatments. The book highlights thefundamental principles of biosensing utilizing theunique properties of nanoscale sensing mechanisms.It is a comprehensive resource for researchers, gradu-ate students, and industrial engineers in this area, withthe emphasis on the unique signal transducing mech-anisms and potential applications of nanoscalebiosensors.

Catalog no. K15174, September 2013, c. 250 pp.ISBN: 978-1-4665-5151-0, $159.95 / £99.00Also available as an eBook

Forthcoming!

Nanotechnologyand HumanHealthEdited by

Ineke MalschMalsch Techno Valuation,Utrecht, Netherlands

Claude EmondAddressing expectations for human health, this bookreviews current scientific and technical developmentsin nanotechnology for biomedical, agrofood, andenvironmental applications. This collection of per-spectives on the ethical, legal, and societal implica-tions of bionanotechnology provides unique insightinto contemporary technological developments.Readers with a technical background will benefit fromthe overview of the state-of-the-art research in theirfield, while readers with a social science backgroundwill benefit from the discussion of realistic prospects ofnanotechnology. The text also includes a glossary aswell as extensive end-of-chapter references.

Catalog no. 8144, August 2013, c. 384 pp.ISBN: 978-0-8493-8144-7, $139.95 / £89.00Also available as an eBook





5

Nanomaterials


Forthcoming!

DNANanotechnologySatyam PriyadarshyRKR Group, Inc., Herndon,Virginia, USA

Latha ShankarWhile DNA has proven to be a versatile molecule thatis ideal for building complex structures at thenanometer scale, until now scientists have lacked acohesive reference that details nanotechnology appli-cations in which DNA plays a key role. This workdescribes current applications across many fields,including robotics, lithography, computation, elec-tronics, and fabrication. Whether you are buildingbiomedical scaffolds, designing molecular motors, orproducing nanowires, this work informs you as towhat has been accomplished and expands yourunderstanding of what is possible.

Catalog no. 86332, September 2013, c. 464 pp.ISBN: 978-1-4200-8633-1, $149.95 / £95.00Also available as an eBook

Forthcoming!

CarbonNanomaterialsSecond EditionEdited by

Yury Gogotsi and Volker PresserDrexel University, Philadelphia,Pennsylvania, USA

Series: Advanced Materials andTechnologies

This book provides information on synthesis, proper-ties, and applications of carbon nanomaterials. Withnovel materials, such as graphene (atomically flat car-bon) or carbon onions (carbon nanospheres), thefamily of carbon nanomaterials is rapidly growing.This book provides a state-of-the-art overview and in-depth analysis of the most important carbon nano-materials. Each chapter is written by a leading expertin the field, which ensures that both a review on thesubject along with emerging perspectives are provid-ed to the readers.


Forthcoming!

RNANanotechnologyandTherapeuticsEdited by

Peixuan GuoUniversity of Kentucky, Lexington, USA

Farzin HaqueInterest in RNA nanotechnology has increased asrecognition of its potential for applications innanomedicine has grown. Edited by the world's fore-most experts in nanomedicine, this comprehensive,state-of-the-art reference details the latest researchdevelopments and challenges in the biophysical andsingle molecule approaches in RNA nanotechnology.In addition, the text provides in-depth discussions ofRNA structure for nanoparticle construction, RNAcomputation and modeling, single molecule imagingof RNA, RNA nanoparticle assembly, RNA nanoparti-cles in therapeutics, RNA chemistry for nanoparticlesynthesis, and RNA conjugation and labeling.


Bio-nanotechnologyConcepts &ApplicationsMaheshwar SharonIIT Bombay (retired), BirlaCollege, NanotechnologyResearch Center, India

Madhuri SharonMonad Nanotech Pvt. Limited, Mumbai, India

Highlighting the human applications of the science,this volume discusses the fundamental concepts andunderlying science of bionanotechnology, and thebionanomachines that result from research into thisexciting new field. Distilling the authors' research andgroundbreaking original experimentation, chapterscover bionanomachines and their use with andmanipulation of DNA, RNA, proteins, carbohydrates,and lipids. Well-documented and authoritative, thisbook offers students and scientists alike the founda-tional information required to advance this powerfuland potentially life-altering field.

Catalog no. K12393, May 2012, 300 pp.ISBN: 978-1-4398-5214-9, $79.95 / £49.99







Nanomaterials

Nano-biomaterialsHandbookEdited by

Balaji SitharamanState University of New York atStony Brook, USA

Nanobiomaterials exhibit distinctive characteristics,which make them suitable for a variety of biologicalapplications. This volume provides a comprehensiveoverview of the field, offering a broad introduction forthose new to the subject as well as a useful referencefor advanced professionals. The book examines various synthesis and processing techniques impor-tant for developing nanobiomaterials, explores theirunique nanoscopic physicochemical properties, discusses potential applications as well as biocompat-ibility issues, and provides a detailed overview of theinteractions between bionanomaterials and biologicalsystems.

Catalog no. 94661, June 2011, 737 pp.ISBN: 978-1-4200-9466-4, $179.95 / £115.00Also available as an eBook

Nanotechnologyin TissueEngineering andRegenerativeMedicineEdited by

Ketul PopatColorado State University, FortCollins, USA

Referred to as "nanomedicine" or "nanobiomedicine,"the application of nanotechnology to medicine canimpact diagnosis, monitoring, and treatment of dis-eases, as well as the control and understanding of bio-logical systems. Bringing together an unparalleledfield of experts, this volume explores various aspectsof nanotechnology and its applications in biomedicalfields. The book uses an application-orientedapproach to relate laboratory-based research to thedevelopment of technologies that are easily adaptableto an industry environment, focusing chiefly on drugdelivery, tissue engineering, and regenerative medicine.


Bestseller!

Fundamentals ofMicrofabricationandNanotechnologyThird Edition, Three-Volume SetMarc J. MadouUniversity of California, Irvine, USA

“… offers the widest and yet the most detailed cov-erage of all essential and fundamental aspects ofmicrofabrication and nanotechnology. The authorhas done an excellent and remarkable job in synthe-sizing such diverse material under a single umbrella.”

—Suman Chakraborty, IIT Kharagpur, India

“Once again, Professor Madou has made an incred-ible contribution to the MEMS/NEMS global com-munity in writing this series of books.”

—Nico de Rooij, Director, Institute of Microengineering,EPFL, Switzerland

A solutions manual, instructor’s manual, and figure slidesare available upon qualifying course adoption

Catalog no. 3180, August 2011, 1992 pp.ISBN: 978-0-8493-3180-0, $259.95 / £166.00

Nano- andBiocompositesEdited by

Alan Kin-tak LauUniversity of SouthernQueensland, Australia and TheHong Kong PolytechnicUniversity, Kowloon

Farzana HussainOregon State University,Corvallis, USA

Khalid LafdiUniversity of Dayton, Ohio, USA

Advances in nanotechnology are leading to the cre-ation of composites with a myriad of medical applica-tions. This forward-thinking book is one of the first tomeld research in biocomposites with advances innanocomposite technology to provide an interdisci-plinary resource on advanced materials for the bio-medical industry. It covers nanostructured polymercomposites, nano/bio composites, developments intissue engineering, safer resins for tooth and bonerepair, and improved artificial joints, along withpotential opportunities for continued research.

Catalog no. 8027X, August 2009, 408 pp.ISBN: 978-1-4200-8027-8, $184.95 / £118.00Also available as an eBook






7

Nanomaterials


UnderstandingNanomedicineAn IntroductoryTextbookRob BurgessMedical NanotechnologiesIncorporated, Richardson, Texas,USA

“In a single book, Dr. Burgess has done an excellentjob in providing the much-needed background in thenumerous physical, chemical, and biological meth-ods that are used to enable nanomedicine. This bookwill be a useful reference for any student in the fieldof nanomedicine and describes many exampleswhere nanotechnology promises to improve thediagnosis, monitoring, and treatment of disease.”

—Dr. Gareth Hughes, Medical Nanotechnologies, Inc.,USA

Catalog no. N10477, June 2012, 524 pp.ISBN: 978-981-4316-38-5, $149.95 / £95.00Also available as an eBook

Forthcoming!

Nanostructuresin BiologicalSystemsTheory andApplicationsAleš Iglič, Damjana Drobne, andVeronika Kralj-IgličUniversity of Ljubljana, Slovenia

This book surveys recent theoretical and experimentalresults on nanostructures in biological systems andexplores possible applications. It presents the theoret-ical approach, which is useful in describing electricaland elastic phenomena in nanostructures in biologicalsystems. The authors use biophysical methods todescribe and indicate manipulation of clinically rele-vant problems, presenting potential clinical uses inhemostasis, inflammation, and spreading of cancer.They also cover interactions between biological mem-branes and inorganic nanostructures.

Catalog no. N10694, July 2013, c. 300 pp.ISBN: 978-981-4267-20-5, $149.95 / £95.00Also available as an eBook

New!

MolecularMotors in Bio-nanotechnologyKeith Firman and James YouellUniversity of Portsmouth, UK

Many techniques have evolved to study and charac-terize molecular motors at the single-molecule level,such as the use of molecular tweezer devices for sin-gle-molecule studies. This book describes a widerange of molecular motors, from chemical to biologi-cal. It introduces readers to the concepts and benefitsof each technique and looks at structural informationand how this helps understand function. The bookalso examines how some of these motors are beingused or may be used in the future as part of a synthetic biology approach to building devices andsensors.

Catalog no. N10568, November 2012, 300 pp.ISBN: 978-981-4267-02-1, $149.95 / £95.00Also available as an eBook

Coming Soon!

NanotechnologyCommercial-izationTakuya TsuzukiDeakin University, Geelong,Australia

In terms of commercialization, nanomaterials occupya unique place in nanotechnology. Engineered nano-materials, especially nanoparticulate materials, are theleading sector in nanotechnology commercialization.In addition, the nanomaterial sector has attractedmuch more heated debate than any other nanotech-nology sector with regard to safety, regulation, stan-dardization, and ethics. This is the first book on nan-otechnology commercialization that deals exclusivelywith nanomaterials. It provides overviews of the cur-rent trends in, and the issues associated with, thecommercialization of nanomaterials by some of theforemost nanotechnology experts in their fields.

Catalog no. N10812, May 2013, c. 450 pp.ISBN: 978-981-4303-28-6, $99.95 / £63.99Also available as an eBook







Complex Tissue & Organs

New!

TissueEngineeringPrinciples andPracticesEdited by

John P. Fisher, Antonios G. Mikos,Joseph D. Bronzino, andDonald R. PetersonPutting the numerous advances in the field into abroad context, this book explores current thoughts onthe development of engineered tissues. It begins withcoverage of the fundamentals, details the supportingtechnology, and then elucidates their applications intissue engineering. It explores strategic directions,nonobiomaterials, biomimetics, gene therapy, cellengineering, and more. The chapters then examinethe applications of these technologies in areas such asbone engineering, cartilage tissue, dental tissue, vas-cular engineering, and neural engineering. It providesa very comprehensive overview of major research top-ics in tissue engineering.

• Includes contributions from experts and pioneers

• Covers emerging topics such as regenerativemedicine, presenting synthetic tissues andorgans that are currently under development

• Discusses the impact of tissue engineering products could have on the future of medicine

Selected Contents:

Fundamentals: Strategic Directions. CalciumPhosphates. Protein Based Biomaterials. SyntheticBiomaterials. Morphogens. Signal Expression.Embryonic Stem Cells. Hematopoietic Stem Cells.Mesenchymal Stem Cells. Enabling Technologies:Nanobiomaterials. Biomimetics. Molecular BiologyTechniques. Biomaterial Mechanics. MechanicalConditioning. Micropatterned Surfaces. DrugDelivery. Gene Therapy. Cell Engineering. CellEncapsulation. Cocultures. Bioreactors. Shear Forces.Vascularization. Bioimaging. Modeling. Applications:Bone Engineering. Craniofacial Engineering. Tendon& Ligament Engineering. Cartilage TissueEngineering. TMJ Engineering. Interfacial TissueEngineering. Dental Tissue Engineering. UrologicalTissue Engineering. Vascular Engineering. NeuralEngineering. Engineering Tumors.

Catalog no. K13429, December 2012, 771 pp.ISBN: 978-1-4398-7400-4, $149.95 / £95.00Also available as an eBook

TissueEngineering andRegenerativeMedicineA Nano ApproachEdited by

Murugan Ramalingam,Pekka Vallittu, Ugo Ripamonti, andWan-Ju Li

"This book broadly covers current topics of tissueengineering. In particular, it would be helpful forthose who are studying in this field based on nan-otechnology and biomaterial science."

—Shoji Takeuchi, The University of Tokyo

This book bridges the gap between nanotechnologyand regenerative medicine to facilitate their transitionfrom lab to the clinic. It compiles important aspects ofbasic science and fundamental principles as well asclinical relevance for current nanotechnological inno-vations in biomaterials and cell, tissue, and organengineering. It also discusses future trends in regener-ative medicine. It is intended for a wide audienceincluding students, researchers, professors, and indus-trial experts working in the fields of biomaterial sci-ence and engineering, nanoscience and nanotechnol-ogy, bioengineering, cell biology, biomedical sciences,tissue engineering, and nanomedicine.

• Supplies an integrated approach to the organization of nanotechnology, biomaterials,bioengineering, and biomedical sciences

• Explains current perspectives and nanotechnological advances in tissue engineering and regenerative medicine

• Covers a range of biomaterials, cells, and theirinteraction for the development of tissues andorgans

• Provides vision for global healthcare systems at the nanoscale level

• Incorporates color figures and tables with current technical and clinical data

Catalog no. K13868, September 2012, 592 pp.ISBN: 978-1-4398-8185-9, $149.95 / £95.00Also available as an eBook




9



New!

Advances inTherapeuticEngineeringEdited by

Wenwei Yu, SubhagataChattopadhyay, Teik-Cheng Lim, and U. Rajendra AcharyaThrough engineering algorithms that provide techno-logical solutions, therapeutic engineering aims to ele-vate the quality of life of disabled individuals. This vol-ume describes various therapeutic processes andmechanisms currently applied to healthcare in a rangeof areas, including mobility, communications, hear-ing, vision, and mental health and cognition. Fromprosthetics to sensory substitution and medical robot-ics, the book will prove enlightening to researchersand practitioners in a host of disciplines who want tounderstand the recent advances achieved globally inthe field of therapeutic engineering.


Coming Soon!

Imaging inCellular andTissueEngineeringEdited by

Hanry Yu and Nur AidaAbdul RahimNational University of Singapore

Series in Cellular and Clinical Imaging

This book covers the full range of available imagingmodalities and optical methods used to help evaluatematerial and biological behavior. It also highlights awide range of optical and biological applications,both in vitro and in vivo. Each chapter in the textdescribes a specific application and discusses relevantinstrumentation, governing physical principles, dataprocessing procedures, as well as advantages and dis-advantages of each modality.

Catalog no. K12139, May 2013, c. 294 pp.ISBN: 978-1-4398-4803-6, $149.95 / £95.00Also available as an eBook

New!

ArticularCartilageKyriacos A. Athanasiou,Eric M. Darling, Grayson D. DuRaine,Jerry C. Hu, and A. Hari ReddiMultitudes of treatments have been devised for artic-ular cartilage injuries, which often degenerate inexpli-cably to disastrous impairment, but no satisfactorylong-term solutions have been established. However,over the past two decades, the swift growth anddevelopment of new knowledge and technologies forcartilage formation, pathology, and repair have beenexciting and inspirational. Written by world-classexperts, this book covers all the latest research andclinical applications related to cartilage tissue engi-neering. It explores the role of nanotechnology andalso provides extensive references at the end of eachchapter.


Forthcoming!

The Law ofRegenerativeMedicine andTissueEngineeringDavid S. SmithPepper Hamilton LLP, Pittsburgh,Pennsylvania, USA

Numerous clinical trials are currently in progress forcomplex tissue constructs and cell therapies.Providing an overview of those legal and regulatoryelements that can significantly impact the clinicalintroduction of cell- and tissue-based products, thistimely volume is an important reference at both thefederal and state level. It discusses guidelines for thenumerous current clinical trials for complex tissueconstructs and cell therapies and considers the devel-opment of strategies for building patent portfoliosand navigating FDA review for market approval.

Catalog no. K11293, August 2013, c. 270 pp.Soft Cover, ISBN: 978-1-4398-2650-8$59.95 / £38.99Also available as an eBook








Polymers forVascular andUrogenitalApplicationsEdited by

Shalaby W. ShalabyPoly-Med Inc., Anderson, SouthCarolina, USA

Karen J.L. BurgClemson University, SouthCarolina, USA

Waleed ShalabyChadds Ford, Pennsylvania, USA

This book covers attributes of polymers used for vas-cular, urological, and gynecological materials. It pro-vides a brief analysis of how the use of polymers invascular and urogenital applications has evolved inthe past five decades and outlines their common andspecific functional requirements. It features small,readable monographs that provide a brief descriptionof the evolving role of a particular material, and pres-ents topics in materials processing and in vitro and invivo evaluation, complete with case studies.

Catalog no. 76949, May 2012, 270 pp.ISBN: 978-1-4200-7694-3, $179.95 / £114.00Also available as an eBook

Forthcoming!

MyocardialTissueEngineeringEdited by

Tatsuya Shimizu andKatsuhisa MatsuuraTokyo Women's MedicalUniversity, Japan

This book broadly summarizes myocardial tissue engi-neering and regenerative medicine, which consists ofmyocardial cell sources, cell therapy for damagedhearts, and tissue engineering technologies for fabri-cating beating hearts. It focuses on myocardial cellsource, cardiac cells differentiated from embryonicstem/induced pluripotent stem cells. Several chaptershighlight innovative technologies developed to over-come the vascularization problem. Remarkable resultsobtained in the past and the present and challengesfor the future in the myocardial tissue engineeringresearch field are described in the book.

Catalog no. N10829, July 2013, c. 400 pp.ISBN: 978-981-4411-31-8, $149.95 / £95.00Also available as an eBook

TissueEngineeringEdited by

John P. FisherUniversity of Maryland, CollegePark, USA

Antonios G. MikosRice University, Houston, Texas,USA

Joseph D. BronzinoTrinity College, Hartford,Connecticut, USA

The ability to engineer biocompatible tissue is the hall-mark of modern biomedical engineering, integratingall aspects of every sub-discipline in the field. Bringingin a diverse group of international contributors withbackgrounds in academia, clinical medicine, andindustry, this volume surveys the latest advances inthis arena. The book discusses the fundamental con-cepts of tissue engineering, enabling technologies,and related applications, examining strategies thatincorporate scaffolds, nanocomposites, bioreactors,drug delivery systems, and gene therapy techniques.

Catalog no. 9026, May 2007, 600 pp.ISBN: 978-0-8493-9026-5, $109.95 / £69.99Also available as an eBook

Forthcoming!

Skin BioscienceA MolecularApproachEdited by

Toyoko ImaeNational Taiwan University ofScience & Technology, Taipei

This book introduces skin bioscience with a specificfocus on the molecular approach. Following thedescription of the fundamental structure and uniquefunctionality of the skin, it examines the response ofthe skin to exterior stimulation. It also focuses on thebeautification and regeneration of the skin. With contributions written by specialists from biophysicsand physical chemistry to regeneration medicine andcosmetics, this book provides readers with the molec-ular knowledge of the skin and stimulates their interest in further investigation and development ofskin bioscience.

Catalog no. N10701, June 2013, c. 200 pp.ISBN: 978-981-4364-95-9, $149.95 / £95.00Also available as an eBook






11

Complex Tissue & Organs Engineering Cells


New!

AdvancedMaterials forJoint ImplantsGiuseppe PezzottiKyoto Institute of Technology,Japan

This book details cutting-edge research in bioceramicsscience based on an interdisciplinary approach thatdirectly bridges orthopedic concepts to surface sci-ence, physical chemistry, biomedical optics, andnanomechanics. Raman and cathodoluminescencespectroscopy are, among more conventional spectro-scopic characterization techniques, cited in the book,used to their most advanced extents to unveil molec-ular scale phenomena of both chemical and mechan-ical origin occurring at the sliding surfaces of bioce-ramic joints. The concepts are relevant to the devel-opment of new biomaterials.

Catalog no. N10574, April 2013, 400 pp.ISBN: 978-981-4316-88-0, $179.95 / £114.00Also available as an eBook

New!

BacterialNanoCelluloseA SophisticatedMultifunctionalMaterialEdited by

Miguel Gama, Paul Gatenholm, andDieter Klemm

Series: Perspectives in Nanotechnology

The first book dedicated to the potential applicationsand unique properties of bacterial cellulose (BC), thisseminal work covers the basic science, technology,and economic impact of this bulk chemical as well asthe companies and patents that are driving the field.It reviews the biosynthesis and properties of BC,including genetics and characterization; discusses theadvancing technology as it relates to product devel-opment, bioreactors, and production; and analyzesthe economic impact of BC on a diverse range ofindustry applications, including materials and bioma-terials, biological and polymer sciences, and electro-mechanical engineering.

• Describes the effects of cultivation conditions on the bacterial nanocellulose (BNC) networkformation, including controlled architecture fortissue engineering

• Reviews a variety of approaches that are available for generation of BNC in differentforms

• Describes commercially available products ofBNC, including nata de coco, wound dressings,cosmetic materials, and tubular BNC blood vessel grafts

• Presents current results concerning the chemicalpolymerization of conducting polymers

Selected Contents:

Biosynthesis of Bacterial Cellulose. Tough BacterialNanocellulose Hydrogels Based on the Double-Network Technique. Bacterial Cellulose SurfaceModifications. Nematic Ordered Cellulose Templates.Wound Dressings and Cosmetic Materials fromBacterial Nanocellulose. Bacterial NanocelluloseHydrogels Designed as Bioartificial Medical Implants.Biomimetic Mineralization of Apatite on BacterialCellulose.


New!

NeuromorphicOlfactionEdited by

Krishna C. PersaudThe University of Manchester, UK

Santiago Marco andAugustin Gutierrez-GalvezUniversity of Barcelona, Spain

Frontiers in Neuroengineering Series

Current understanding of biological components ofchemical sensing systems makes it possible to consid-er biomimetic models of olfaction and how they maybe translated into functional engineering devices. Thisbook presents an innovative interdisciplinary bio-mimetic approach to olfaction, including biology,hardware, software, and sensors. The text explorescontributions to the realization of novel chemicalsensing systems inspired by biological pathways,describing cutting-edge research such as engineeringaspects of olfaction, odor coding of neurons, chemicalsensor arrays, and biologically modeled sensor robots.

Catalog no. K13286, April 2013, 234 pp.ISBN: 978-1-4398-7171-3, $149.95 / £95.00Also available as an eBook






Engineering Cells

New!

Mechanics ofCellular BoneRemodelingCoupled Thermal,Electrical, andMechanical FieldEffectsQing-Hua QinAustralian National University, Acton

This volume presents a unified exploration of recentadvances in bone remodeling, including its mathe-matical representation, giving readers a sound under-standing of the process at both the macro- and cellu-lar level. Beginning with a description of the basic con-cept of bone remodeling from a mathematical point ofview, the book details the development of each of thetechniques and ideas. From there it progresses to thederivation and construction of multifield and cellularbone remodeling and shows how they arise naturallyin response to external multifield loads.

Catalog no. K16026, January 2013, 320 pp.ISBN: 978-1-4665-6416-9, $139.95 / £89.00Also available as an eBook

Forthcoming!

Biology of OralCancerKey ApoptoticRegulatorsPrakash S. BisenDefense Research & DevelopmentEstablishment, Gwalior, India

Zakir KhanSaurabh BundelaOne new approach in dealing with cancer is throughapoptotic regulators, which is the process of control-ling cell growth by abnormally prolonging cell sur-vival, facilitating the accumulation of transformingmutations and promoting resistance. With contribu-tions from world-class experts, this book uses oral can-cers as the specific means to demonstrate this tech-nique with this particular type of cancer, which isquite prevalent (and deadly) in India and other partsof Asia, in particular.

Catalog no. K16715, July 2013, c. 328 pp.ISBN: 978-1-4665-7558-5, $139.95 / £89.00Also available as an eBook

New!

Biomaterials forStem CellTherapyState of Art andVision for the FutureEdited by

Loredana De BartoloInstitute on MembraneTechnology, Rende, Italy

Augustinus BaderCenter for Biotechnology and Biomedicine (BBZ), Leipzig,Germany

This book provides state-of-the-art developments witha focus on the interaction of stem cells with biomate-rials for constructing and regenerating tissues andorgans integrating strategies from basic biology, tomaterials for remodeling, to production processes.Stem cells of embryonic and adult origin are discussedwith applications including nerve regeneration, liver,pancreas, skin, trachea, cartilage and bone repair, andcardiovascular therapy. All developments in the fieldreflecting the design and construction of the humanbody and its principal anatomy are discussed from amaterials point of view.


MechanobiologyHandbookEdited by

Jiro NagatomiClemson University, SouthCarolina, USA

Mechanobiology examines effects of mechanical forcestimuli on cellular biological functions. At appropriatelevels, mechanical stimuli are necessary for growthand maintenance of healthy tissues and organs. Thepast two decades have seen a dramatic increase in thelevel of research in mechanobiology. Collecting thecutting-edge research findings from a diverse range ofscientists, this volume presents basic materials inmechanics and cell biology. The book is an appropri-ate reference for those new to the field and isdesigned to stimulate new ways of thinking in currentmechanobiology researchers.

Catalog no. 91212, March 2011, 563 pp.ISBN: 978-1-4200-9121-2, $179.95 / £115.00Also available as an eBook






13

Engineering Cells Biotechnology


Biomaterialsand Stem Cellsin RegenerativeMedicineEdited by

Murugan RamalingamSeeram RamakrishnaNational University of Singapore

Serena BestUniversity of Cambridge, UK

This book brings together current knowledge on bio-materials and stem cells in the context of regenerativemedicine. It explores key scientific and clinical aspects,including the basic science involved in structure andproperties, techniques and technological innovations inprocessing and characterization, and applications. Thetext bridges the gaps in experimental approaches andunderstanding among the materials science and engi-neering, biological sciences, and biomedical scienceand engineering communities, making it a valuable ref-erence for multidisciplinary biomedical research.

Catalog no. K13711, July 2012, 564 pp.ISBN: 978-1-4398-7925-2, $149.95 / £95.00Also available as an eBook

New!

OMICSApplications inBiomedical,Agricultural, andEnvironmentalSciencesEdited by

Debmalya Barh,Vasudeo Zambare, andVasco AzevedoFeaturing contributions from active researchersaround the world, this book explores current andemerging fields such as glycomics, miRNA, metage-nomics, and environomics and their various applica-tions. It examines a wide range of applications acrossthe life sciences, demonstrating the real diversity ofomics. This timely book discusses toxicogenomics inthe assessment of environmental pollutants, plantmetabolomics, nutrigenomics and its therapeuticapplications, microalgal omics, omics for biofueldevelopment, omics approaches for crop improve-ment and environmental sustainability, breast cancerbiomarkers, and much more.


New!

Handbook ofTherapeuticBiomarkers inCancerEdited by

Sherry X. YangNational Cancer Institute,Bethesda, Maryland, USA

Janet E. DanceyOntario Institute for Cancer Research, Toronto, Canada

In this volume, a team of internationally recognizedexperts provides an in-depth description of therapeu-tic biomarkers across a broad area of cancer researchand oncology. With a wealth of information to specif-ic therapies, each chapter focuses on a class of target-ed chemotherapy agents. The book describes estab-lished and evolving diagnostic tests for therapeuticbiomarkers that predict benefit, response, resistance,or drug side effects from specific therapeutic interven-tions. This volume is an essential handbook for healthprofessionals and scientists researching current appli-cable biomarkers in oncology.

Catalog no. N10578, April 2013, 450 pp.ISBN: 978-981-4364-65-2, $179.95 / £114.00Also available as an eBook

OMICSBiomedical Perspectivesand ApplicationsEdited by

Debmalya BarhInstitute of Integrative Omics andApplied Biotechnology (IIOAB),Purba Medinipur, West Bengal,India

Kenneth Blum andMargaret A. MadiganLifeGen, San Diego, California, USA

A reflection of the explosion of research and develop-ment in this field, this book explores applications ofomics in bioinformatics, cancer research and therapy,diabetes research, plant science, molecular biology,and neurosciences. It collates recent developments inthe field into a state-of-the-art framework for this dis-cipline. A select panel of experts discusses their cut-ting-edge omics research and novel technologies,supplying a basic platform of methods and applica-tions as well as a multi-omics approach to futureendeavors in the fertile areas of omics research.








Biotechnology

Biological and BiomedicalCoatings Handbook

Two-Volume SetEdited by Sam Zhang

Nanyang Technological University, Singapore

Important in today’s nanotechnology, biological andbiomedical coatings have been studied extensivelyand are receiving much attention from researchers. Atimely reference for experts and newcomers, thishandbook explores the latest developments in filmsand coatings for biological and biomedical applica-tions. The text covers a wide array of material types,including sol-gel, bio-ceramics, polymers, glass, nano-materials, and chitosan. It also addresses variousprocesses for developing and implementing thesecoatings, including CVD and PVD, drug delivery,released-control coatings, and spectroscopy.• Covers processing, properties, and performance• Includes information on drug delivery and

released-control coatings• Presents cutting-edge developments from world

leaders in films and coatings research• Serves as a simplified introductory stepping

stone for new entrants to the field• Gives experts up-to-date figures, tables, plots,

and images to aid their own work

Catalog no. K11126, May 2011, 976 pp.ISBN: 978-1-4398-2125-1, $259.95 / £166.00Also available as an eBook

HealthcareBiotechnologyA Practical GuideDimitris DogramatzisDogramatzis Pharmacy, Athens,Greece

Focusing on the management of healthcare-relatedbiotechnology, this text is a practical guide assisting allhealthcare related biotech professionals in their day-to-day activities. It contains chapters on bioeconomy, bio-licensing, biofinance, biopartnering, biodrug research,biomarket planning, biopromotion, product life cyclemanagement, and biobusiness models. Written by awell-established professional and registered pharma-cist, this reference is appropriate for graduate studentsand industry professionals. It contains over 350 tablesand figures, and end-of-section problems and exten-sive references accompany each chapter.

A solutions manual, instructor's manual, and figure slidesare available upon qualifying course adoption


Also available as individual volumes

Biological and BiomedicalCoatings HandbookProcessing andCharacterizationCatalog no. K12269, May 2011, 456 pp.ISBN: 978-1-4398-4995-8, $146.95 / £94.00

Biological and BiomedicalCoatings HandbookApplicationsCatalog no. K12270, May 2011, 520 pp.ISBN: 978-1-4398-4996-5, $146.95 / £94.00Individual volumes also available as eBooks

BiotechnologyOperationsPrinciples andPracticesMichael J. RoyUniversity of Wisconsin-Madison,USA

This book introduces key biotechnology develop-ments and covers critical elements, such as projectmanagement, regulatory affairs, quality assurance,biomanufacturing, quality control, nonclinical safetytesting, and clinical evaluation. The author discussesthese subjects in relation to development planning,process and pathways, management of integratedprojects, and the business and economic aspects ofdevelopment. Using simple language and explanato-ry figures, it describes the functional areas that mustbe successfully integrated to safely and efficientlybring a biotechnology product to market.

A solutions manual and figure slides are available uponqualifying course adoption








15

Biotechnology Materials Science


Porous MediaApplications inBiological Systemsand BiotechnologyEdited by

Kambiz VafaiUniversity of California, Riverside,USA

This volume explores innovative approaches to effec-tively apply existing porous media technologies tobiomedical applications. In each peer-reviewed chap-ter, world-class scientists and engineers address signif-icant problems and discuss exciting research in bio-logical systems. They cover various transport process-es, mechanical behavior, and material properties ofbiological tissues from a porous media point of view.The book also presents pertinent aspects of experi-mental work and numerical techniques and discussesthe modeling of several phenomena, including flowchanges in cerebral aneurysms, biomass growth,marine systems, and tissue homeostasis and repair.

Catalog no. 65416, August 2010, 632 pp.ISBN: 978-1-4200-6541-1, $157.95 / £101.00Also available as an eBook

New!

BiomaterialsPrinciples andPracticesEdited by

Joyce Y. WongBoston University, Massachusetts,USA

Joseph D. BronzinoSimsbury, Connecticut, USA

Donald R. PetersonUniversity of Connecticut, Farmington, USA

Most current applications of biomaterials involvestructural functions—even in those organs and sys-tems that are not primarily structural in their nature—or very simple chemical or electrical functions.Complex chemical functions such as those of the liverand complex electrical or electrochemical functionssuch as those of the brain and sense organs cannot becarried out by biomaterials at this time. With thesebasic concepts in mind, this book focuses on bioma-terials consisting of different materials such as metal-lic, ceramic, polymeric, and composite. It highlightsthe impact of recent advances in the area of nano-and microtechnology on biomaterial design.

• Discusses the uses of materials in medicine anddentistry

• Covers recent advances in the development ofbiomaterials

• Include contributions from experts and pioneersin this field

• Examines how the role of biomaterials has beeninfluenced by advances in many areas ofbiotechnology and science

Selected Contents:

Metallic Biomaterials. Ceramic Biomaterials.Polymeric Biomaterials. Composite Biomaterials.Biodegradable Polymeric Biomaterials: An UpdatedOverview. Biologic Biomaterials: Tissue-DerivedBiomaterials (Collagen). Biologic Biomaterials: Silk.Biofunctional Hydrogels. Soft Tissue Replacements.Hard Tissue Replacements.


MacroporousPolymersProduction Propertiesand Biotechnological/BiomedicalApplicationsEdited by

Bo MattiassonLund University, Sweden

Ashok KumarIndian Institute of Technology, Kampur, India

Igor Yu. GaleaevLund University, Sweden

Presented in a systematic way, this book addresses theproduction, characterization, and application of thesepolymers. The text considers traditional methods ofproduction, including phase separation polymeriza-tion, leaching, foaming, and double emulsion, as wellas newly merging methods such as cryogelation. Thechapters also detail the various applications of macro-porous gels for the separation of biomolecules and forthe cultivation of mammalian cells in bioreactors, aswell as for tissue engineering.

Catalog no. 84615, December 2009, 525 pp.ISBN: 978-1-4200-8461-0, $146.95 / £94.00Also available as an eBook






Materials Science

New!

MarineBiomaterialsCharacterization,Isolation andApplicationsEdited by

Se-Kwon KimPukyong National University,Busan, South Korea

Presenting a groundbreaking platform to assist indevelopment of new biotechnology start-ups andenterprises, this book describes current trends inmarine materials for a range of fields including tissueengineering, drug delivery, bioenergy, and adhesiveproducts from preliminary research to clinical trial.Essential reading for the novice and expert alike, itdetails the isolation and characterization of appropri-ate materials, methods for the extraction and applica-tion of marine materials, the viability of low-costmarine biomaterials, and the potential role of the bio-logical applications to diseases such as inflammation,diabetes, arthritis, and cancer.

• Offers very thorough coverage of isolation andcharacterization as well as the industrial andmedical applications of marine materials

• Delineates the potential role of the biologicalapplications to diseases such as inflammation,diabetes, arthritis, and cancer

• Expounds on the viability of low-cost marinebiomaterials as compared to synthetic biomaterials which possess unwanted degradative characteristics

• Contains an extensive reference list in eachchapter to encourage further study

Selected Contents:

Introduction to Marine Biomaterials: BackgroundStudy. History of Marine Biomaterials. Scope ofMarine Biomaterials. Source, Isolation andCharacterization Aspects of Marine Biomaterials:Ceramics. Carbohydrates. Enzymes or Peptides.Algae Based Products (Nanoparticles). Lipids.Pigments. Toxins. Corals. Biological Application ofMarine Biomaterials: Antioxidant. Anti inflammation.Anticancer. Anticoagulant. Antiviral Activity.


Szycher'sHandbook ofPolyurethanesSecond EditionEdited by

Michael Szycher, Ph.DSterling Biomedical, Inc.,Lynnfield, Massachusetts

"... a valuable resource ... brings together informa-tion from a wide variety of academic and commer-cial sources. The handbook contains a wealth ofinformation from the patent literature which reflectsthe commercial importance of polyurethanes andprovides direction for future research and develop-ment activities."

—Andrew M. Reed, Ph.D., President, AMRAR, LLC

Written as a reference for polyurethane technologistsand end users, raw materials suppliers, and students inthe field, this second edition covers the technicaladvances in the field over the past ten years. Itincludes new data on green polyurethanes, automo-tive applications, new coatings, new manufacturingequipment, new healthcare uses, and other topics.Individuals from all major polyurethane intermediatesuppliers and equipment manufacturers contributedto this updated handbook, and discuss current prod-ucts and provide a comprehensive list of product port-folios.

• Includes comprehensive coverage of allpolyurethane applications

• Provides a multi-source compilation of currentpolyurethane technologies

• Offers information on suppliers, equipment, and laboratory analysis

• Presents figures, charts, graphs, and photographs

Selected Contents:

Basic Concepts in Polyurethane Chemistry andTechnology. Structure–Property Relations inPolyurethanes. Isocyanate Chemistry. Polyols. ChainExtenders. Flexible and Semiflexible Foams. RigidPolyurethane Foams. Polyurethane Foam Surfactants.Catalysis of Isocyanate Reactions. Elastomers.Reaction Injection Molding. Polyurethane Adhesives.Waterborne Polyurethanes. Health and Safety.Radiation-Curable Adhesives and Coatings.





17

Materials Science


Materials inBiology andMedicineEdited by

Sunggyu LeeOhio University, Athens, USA

David HenthornSt. Louis University, Missouri,USA

Series: Green Chemistry and Chemical Engineering

"… a timely addition to the field … Cutting-edgearticles by leading experts review critical areas cov-ering biomaterials and biomimetic materials, mate-rials function and response modification, and med-ical device development. Each application-orientedchapter provides the relevant scientific and engi-neering background with extensive references forfurther study and research. The contributors usemultiple examples to provide rich insights into abroad array of biomaterial applications for a targetaudience consisting of graduate students, materialsscientists, research engineers, and academic physi-cians and surgeons."

—Dr. Sunil K. Kesavan, Akebono Inc., Farmington Hills,Michigan, USA

• Illustrates the emerging technological advancesin the field

• Provides the necessary scientific background ofall application areas covered

• Explains the technological details underlying theapplications

• Promotes novel process and product development efforts using green chemistry and engineering

• Emphasizes the enhancement and modificationsof the functionality of materials

Selected Contents:

Introduction: Materials in Biology and Medicine.Biomaterials. Hydrophilic Polymers for BiomedicalApplications. Hydrogels. Polyanhydrides. FunctionalBiomaterials. Molecularly Imprinted Polymers.Functionalization of Carbon Nanotubes. Animal CellCulture. Tissue Engineering. Bioactive Devices. CellEncapsulation. BioMEMS. Immobilized EnzymeTechnology. Biocompatibility-Imparting NanofilmCoating.


BiomaterialsScienceAn IntegratedClinical andEngineeringApproachEdited by

Yitzhak RosenSuperior NanoBioSystems, SilverSpring, Maryland, USA

Noel ElmanCambridge, Massachusetts, USA

"… offers a good overview of biomaterials as med-ical devices, drug delivery and tissue engineering sys-tems. The emphasis is on integrating clinical andengineering approaches. In particular, the book cov-ers various applications of biomaterials in unmetclinical needs in variety of fields … covers areas suchas regulatory challenges and commercializationissues."

—From the Foreword by Robert Langer, MassachusettsInstitute of Technology, Boston, USA

"This book is essential when designing, developingand studying biomedical materials.… provides anexcellent review—from a patient, disease, and evengenetic point of view—of materials engineering forthe biomedical field. I found very interesting factsabout patient study combined with clinical study ofmaterials. This well-presented book strongly insistson how the materials can influence patients’ needs,the ultimate drive for biomedical engineering.

—Fanny Raisin-Dadre, BioInteractions Ltd., Berkshire, England

• Discusses hemocompatibility

• Covers medical applications of BioMEMS andnanotechnologies

• Explores biomaterials in dental, neurosurgical,obstetrics/gynecology, and medical device applications

• Addresses tissue engineering with focus on cardiovascular and musculoskeletal systems

• Talks about regulatory challenges and innovativeproduct development and technology adoption

• Examines controlled drug delivery

Catalog no. K10223, June 2012, 310 pp.ISBN: 978-1-4398-0404-9, $149.95 / £95.00Also available as an eBook





Materials Science

New!

Corrosion ofCeramicMaterialsThird EditionRonald A. McCauleyRutgers, The State University ofNew Jersey, Piscataway, USA

Series: Corrosion Technology

“… a comprehensive guide to the fundamentalaspects of corrosion in inorganic crystalline andglassy materials. The book is a thorough descriptionof fundamentals, mechanisms, testing, and methodsto reduce corrosion for a wide range of engineeringapplications. This text provides an introductory treat-ment of corrosion of ceramics that enables both engi-neering students as well as working professionals tounderstand and advance their knowledge on the sub-ject. Research scientists and engineers in ceramics,metallurgy, and other materials-related industries willfind the book particularly valuable for this reason.”

—Richard Haber, Rutgers University


Forthcoming!

Polymer andPolymer-HybridNanoparticlesFrom Synthesis toBiomedicalApplicationsStanislav RangelovAsterios PispasWritten for graduate students and researchers in thefields of chemistry, pharmacy, nanosciences, and bio-medical engineering, this timely reference reviewspolymer synthesis and macromolecular design andvarious applications of polymer-based nanomaterialsin bionanotechnology and medicine. It provides adescription of the current state of the art of the field,summarizing important developments in the field andcondensing the relevant research into a comprehen-sive reference. Differing from other references of sim-ilar topic, this book provides an interdisciplinarybridge between polymer synthesis and characteriza-tion and biomedical aspects.


Coming Soon!

HydroxyapatiteCoatings forBiomedicalApplicationsEdited by

Sam ZhangNanyang TechnologicalUniversity, Singapore

Series: Advances in Materials Science and Engineering

“This is a well-written book containing importantup-to-date information pertaining to the fabrica-tion, properties, and applications of hydroxyapatitecoatings. I highly recommend this book to engineersand researchers working in the field, particularlygraduate students.”

—Paul K. Chu, City University of Hong Kong

This handbook covers characterization and applica-tions of Hydroxyapatite (HA). It details HA coatingsand use in dental implants, biomimetic HA materials,electrochemical and pulsed laser deposition, drugdelivery, and more. Seasoned professionals at everylevel will find it a valuable resource.


Forthcoming!

OpticalTechniques inRegenerativeMedicineEdited by

Stephen P. Morgan andFelicity R.A.J. RoseUniversity of Nottingham, UK

Steve J. MatcherUniversity of Sheffield, UK

This book is focused on optical techniques that can beapplied to regenerative medicine, including opticalcoherence tomography, acousto-optic imaging,Raman spectroscopy, machine vision, fibre optic sen-sors, second harmonic generation, polarized lightimaging, and more. Each chapter gives an overview ofa particular technique, its advantages and limitationsin terms of structural and functional information pro-vided, and examples of applications in regenerativemedicine. The book provides a practical guide to themost appropriate techniques for a given applicationand offers a summary of major recent advances.







19

Materials Science


New!

PolymericBiomaterials2 Volume Set, Third EditionEdited by

Severian DumitriuUniversity of Sherbrooke,Canada

Valentin PopaTechnical University of Iasi, Romania

The third edition of a bestseller, this comprehensivereference presents the latest polymer developmentsand most up-to-date applications of polymeric bio-materials in medicine. This substantially largerresource contains 53 chapters in two volumes, whichinclude state-of-the-art research and successful break-throughs in applications that have occurred in the lastten years. Completely revised and expanded, the thirdedition covers the structure and properties of synthet-ic and natural polymers as well as applications of poly-meric biomaterials including drug delivery, tissueengineering, anticancer therapies, hydrogels, andbioartificial organs.

Catalog no. 94726, January 2013, 1710 pp.ISBN: 978-1-4200-9472-5, $329.95 / £210.00Also available as an eBook

PhysicalProperties ofMaterialsSecond EditionMary Anne WhiteDalhousie University, Halifax,Nova Scotia, Canada

“This book stands out as a unique resource for stu-dents and established scientists working at the mod-ern materials/chemistry/technology interface. It con-veys a tremendous amount of information and dis-tills the physics and chemistry down to an intuitivelevel that can be appreciated by both developing sci-entists as well as more established scientists lookingfor a teaching aid/text or a tune-up in their ownknowledge.”

—Timothy M. Swager, Massachusetts Institute ofTechnology, Cambridge, USA



Biological andMedical SensorTechnologiesEdited by

Krzysztof IniewskiCMOS Emerging Technologies,Inc., Vancouver, British Columbia,Canada

Series: Devices, Circuits, andSystems

Edited by a pioneer in the area of advanced semicon-ductor materials, this book contains contributionsfrom experts, exploring the development and use ofsensors in biological and medical applications. It cov-ers topics including advanced sensing and communi-cations in biology, as well as physics and modeling ofDNA-derivative architecture, and the use of enzymeand quartz crystal microbalance-based biosensors.The book also addresses biosensors in human behav-ior measurement, sweat rate wearable sensors, andthe future of medical imaging.

Catalog no. K13895, February 2012, 412 pp.ISBN: 978-1-4398-8267-2, $149.95 / £95.00Also available as an eBook

BiomimeticsNature-BasedInnovationEdited by

Yoseph Bar-CohenJPL/Caltech, Pasadena,California, USA

This book documents key biological solutions thatprovide a model for innovations in engineering andscience. Leading experts explore a wide range of top-ics, including artificial senses and organs; mimicry atthe cell–materials interface; modeling of plant cell wallarchitecture; biomimetic composites; artificial mus-cles; biomimetic optics; and the mimicking of birds,insects, and marine biology. The book also discussesapplications of biomimetics in manufacturing, prod-ucts, medicine, and robotics; biologically inspireddesign as a tool for interdisciplinary education; andthe biomimetic process in artistic creation.








Materials Science

Chitosan-BasedHydrogelsFunctions andApplicationsEdited by

Kangde Yao, Junjie Li,Fanglian Yao, and Yuji YinTianjin University, People'sRepublic of China

This work details the latest progress in the researchand development of chitosan-based biomaterials, pro-viding the foundation for future research. The bookintroduces the formation and chemical structure ofchitosan-based hydrogels. It also discusses the rela-tionship between their structure and functions, whichprovides a theoretical basis for the design of biomate-rials. In addition, many real-world examples illustratethe potential application of chitosan-based hydrogelsin various fields, including materials science, biotech-nology, pharmaceuticals, regenerative medicine, andcell engineering.


Forthcoming!

BiofunctionalSurfaceEngineeringEdited by

Martin ScholzLEUKOCARE AG, Munich,Germany

The lack of effective sterilization techniques for bio-logics has spawned discussions about the reduction ofregulatory requirements, which might impose signifi-cant safety risks. On the other hand, novel and safetechnologies enable the coupling, stabilization, andprotection of effector molecules in a way that allowsterminal sterilization without loss of function. Thisbook provides a comprehensive overview on the stateof the art and the future of "biofunctional surfaceengineering" and will be of major interest for all thoseworking in the fields of medicine and medical devices.

Catalog no. N10827, August 2013, c. 300 pp.ISBN: 978-981-4411-60-8, $149.95 / £95.00Also available as an eBook

PolyurethaneShape MemoryPolymersW.M. HuangNanyang Techological University,Singapore

Bin YangHelvoet Rubber & PlasticTechnologies Pte Ltd., Singapore

Yong Qing FuHeriot Watt University, Edinburgh, UK

"One in all, the authors managed to write a bookwhich gives a comprehensive overview onpolyurethane shape memory polymer research. Dueto the authors’ long-term research experience, I amoptimistic that Polyurethane Shape MemoryPolymers will be a success story. Everyone, whowants to learn about these fascinating materials orget inspired, will find plenty of information and avaluable source of inspiration."—Dr. Thorsten Pretsch, BAM Federal Institute for Materials

Research and Testing, Berlin, Germany


New!

Advances in theEngineering ofPolysaccharideMaterialsby Phosphorylase-Catalyzed EnzymaticChain-ElongationJun-ichi Kadokawa andYoshiro KanekoKagoshima University, Japan

Polysaccharides and related compounds are attractingmuch attention due to their potential as new func-tional materials in many research fields such as medi-cine, pharmaceutics, foods, and cosmetics. Therefore,precision synthesis of new polysaccharides with well-defined structure is increasingly important. For thispurpose, enzymatic method is a very powerful toolbecause the reaction proceeds in a highly stereo- andregion-controlled manner. This book focuses onadvances in the practical synthesis of polysaccharidesby phosphorylase-catalyzed chain-elongation fromthe perspective of polysaccharide engineering.

Catalog no. N10553, March 2013, 200 pp.ISBN: 978-981-4364-45-4, $129.95 / £82.00Also available as an eBook






21

Drug Delivery


Nanomedicinein Drug DeliveryEdited by

Arun KumarMarshall University, Huntington,West Virginia, USA

Heidi M. MansourUniversity of Kentucky, Lexington,USA

Adam FriedmanAlbert Einstein College of Medicine, Bronx, New York, USA

Eric BloughMarshall University, Huntington, WV, USA

"The book covers a wide range of interesting topics,which are well organized, covering both the physico-chemical characterization of the drug delivery systemsand their potential clinical applications. ... In theupcoming decade, nanotechnologies are expected toprovide innovative delivering devices to meet crucialclinical needs. In this context, the main strength of thisbook is to provide a comprehensive discussion aboutthe most promising approaches for diagnosis andtreatment of diseases. The editors are worldwide recog-nised experts in the field and have gathered a team ofcontributors to cover the several applications of nano-sized materials in medical and life-sciences fields. Thisbook will help both beginners and experienced profes-sionals working in the field of drug delivery."

—Eliana B. Souto, Faculdade de Ciências da Saúde,Universidade Fernando Pessoa, Porto, Portugal

Focusing exclusively on the design, synthesis, andapplication of nanoparticles in a range of applications,this book illustrates how nanotechnology can tackledrug delivery challenges as well as addressing the usesof nanotechnology for both diagnosis and treatmentof disease. It addresses nanoparticulate use in severalbiomedical applications including administrationroutes, controlled release, and MRI contrast enhance-ment. Drawing on contributions by leading experts inthe field, it presents a wide range of clinical applica-tions supported by examples and case studies.

• Focuses exclusively on nanomedicine/drug delivery combination

• Illustrates nanoparticle descriptions in all drugdelivery systems

• Covers several biomedical applications ofnanoparticles along with administration routesand controlled release

• Presents clinical application-oriented materialwith examples and case studies

• Draws on contributions by the leading expertsof the field

Catalog no. K14612, June 2013, c. 464 pp.ISBN: 978-1-4665-0616-9, $159.95 / £99.00Also available as an eBook

Forthcoming!

NanoparticlesDrug InhalationTherapyEdited by

Akira TsudaHarvard University, Cambridge,Massachusetts, USA

Peter GehrUniversity of Bern, Switzerland

Nanoparticles have a physical dimension comparableto the size of molecular structures on the cell surface.Therefore, nanoparticles are considered to behave dif-ferently than larger particles when they interact withcells. This book describes the sequence of events thatairborne nanoparticles encounter in the lungs whenthey move from air to the bloodstream. This includesdeposition, events occurring on the alveolar surface(retention and clearance, and interaction with surfac-tant and with alveolar lining fluid), crossing theair–blood tissue barrier, and finally getting into thebloodstream.


Nanotechnologyfor the Deliveryof TherapeuticNucleic AcidsEdited by

Dan PeerTel Aviv University, Israel

Written by world experts in the field of nanotechnol-ogy for nucleic acid (NA) delivery, the authors explorethe state of the art in delivery strategies using lipids,polymers, chemical conjugates, NA aptamers, andproteins. They strongly emphasize issues and aspectsthat are of essence to the pharmaceutical industryworking in areas such as stability, general toxicity,immune-toxicity, pharmacokinetics, and the efficacyand validation of new drug targets in vivo by usingunique approaches based on exquisite nanotechnolo-gy strategies. The contributing authors are world lead-ers in their respective fields and founders of differentapproaches.

Catalog no. N10808, March 2013, c. 400 pp.ISBN: 978-981-4411-04-2, $149.95 / £95.00Also available as an eBook






Biomaterials Education

Ultrasonic andElectromagneticNDE forStructure andMaterialCharacterizationEngineering andBiomedicalApplicationsEdited by

Tribikram KunduThe University of Arizona, Tucson, USA

"The book comprises an essential reference forresearchers and graduate students working in ultra-sonic or electromagnetic NDE. The different chapterscontributed by recognized experts in the field coverboth fundamental theory as well as current researchareas."

—Dr. Paul Fromme, University College London, UK

"Professor Kundu is to be congratulated for bringingtogether this list of experts, each with many years ofexperience, as contributors to this much-needed book.The book provides a comprehensive and rigorousapproach of the fundamentals of linear and nonlinearultrasonics and electromagnetic methods, including achapter on the newly emerging THz technique. Thebook also provides enough advanced engineeringand biological applications to make the reader famil-iar with these technologies, including applications ofguided waves, nonlinear ultrasonics, laser-ultrasonics,acoustic microscopy, and fiber optics.”

—Henrique Reis, Department of Industrial and EnterpriseSystems Engineering, University of Illinois at Urbana-

Champaign, USA


Selected Contents:

Mechanics of Elastic Waves and UltrasonicNondestructive Evaluation. Modeling of UltrasonicFields by Distributed Point Source Method.Electromagnetic Nondestructive Evaluation.Distributed Point Source Method for Imaging inElectrostatic and Electromagnetic Problems. GuidedWaves for Plate and Pipe Inspection. Fundamentalsand Applications of Nonlinear UltrasonicNondestructive Evaluation. Theory and Applicationsof Laser Ultrasonic Techniques. MaterialCharacterization by Nonlinear Ultrasonic Technique.Toward Structural Health Monitoring Solutions forBolted Joints.


Forthcoming!

RegenerativeEngineeringEdited by

Cato T. Laurencin andYusuf KhanUniversity of Connecticut HealthCenter, Farmington, USA

Regenerative engineering is the intersection of regen-erative medicine and tissue engineering. Regenerativemedicine focuses on the biological aspects of tissueregeneration via stem cells, factors, and cytokines,while tissue engineering focuses on the integration ofmaterials science and life sciences. This book inte-grates these two areas, presenting each concept inthe framework of regenerative engineering. Throughthe combination of fundamental lecture-based teach-ing and problem-based learning approaches, it is thegoal of this textbook to develop students into futureresearchers capable of completing the translation oftheir work from the benchtop to the bedside.

• Addresses both tissue engineering and regenerative medicine

• Synergizes the fields of tissue engineering, materials science, and regenerative medicine

• Guides the reader in research based on clinicallyrelevant issues using a problem-based learningapproach

• Includes examples, case studies, and extensivereferences


Selected Contents:

Introduction

Basic Cell Biology

Morphogenesis and Developmental Biology

Basic Anatomy and Physiology

Basic Materials Science

Biomaterials

Introduction to Regenerative Engineering

Organ Regenerative Engineering

Cardiovascular Regenerative Engineering

Musculoskeletal Regenerative Engineering

Neural Regenerative Engineering





23



New!

Learning Bio-Micro-NanotechnologyMel I. MendelsonLoyola Marymount University,Los Angeles, California, USA

"… a great combination of two key disciplines in thecoming quarter of this century, biotechnology andnanotechnology. This will be a good guidebook forthe academic adventure as well as a bible for thepioneer in the engineering and scientific field."

—Hideyuki Kanematsu, Suzuka National College ofTechnology

"… provides an excellent, multi-dimensionalapproach to learning that I have not seen in othernanotechnology textbooks. … I really like the multi-tude of ways the author has the students thinkabout the material through problems, group activi-ties, thinking exercises, etc."

—Kory Goldammer, Richland College

A primary text for undergraduate nanotechnologycourses, this book is designed for students who lack across-disciplinary background and knowledge ofmicro- and nanotechnology. Clearly and conciselywritten, it contains many examples, questions, andproblems divided into three hierarchical learning skills:understanding, analyzing, and evaluating the con-cepts. The author attempts to break down the bound-aries between biology, chemistry, physics, engineer-ing and ethics. He accomplishes this by co-minglingthe vocabulary and concepts of these disciplinesaround bio-applications. Copiously illustrated, thisnew text leans heavily towards biological and bio-medical applications and includes a comprehensivechapter on ethics.

A solutions manual is available upon qualifying courseadoption

Selected Contents:

Thinking Small and Big. Biomolecules and Cells.Molecular Chemistry. Bit of Physics. Engineering Bitsand Bytes. Seeing Small Things. Nanoelectronics.Microelectromechanical Systems. Nanotechnologyand Cancer. Risks: Nano or Mega? Ethics and SocialRelevance. Self-Assembled Future. Appendices.

Catalog no. 82035, January 2013, 611 pp.ISBN: 978-1-4200-8203-6, $89.95 / £57.99Also available as an eBook

Introduction toBiomedicalEngineeringTechnologySecond EditionLaurence StreetRosedale, British Colombia,Canada

Thoroughly revised and updated, this second editiondescribes current technological devices, the physio-logical and anatomical basis of their function, theirpractical applications, and their common locations inhospitals. Written by an experienced biomedical engi-neering technologist, the text discusses tools and testequipment, examines the integration of equipmentwithin the hospital system, and presents an overviewof various kinds of hardware related to medical equip-ment. Throughout, this accessible book incorporatesreal-life examples of the work that biomedical engi-neering technologists do, preparing students for situ-ations they will encounter on the job.

• Covers a wider range of devices and includes anexpanded section on equipment management

• Offers chapter summaries and questions to aidin reader comprehension

• Contains more than 360 illustrations

• Includes a 16-page grayscale insert with photographs of real-life equipment problems


Selected Contents:

Introduction. Diagnostic Devices: Part One.Diagnostic Devices: Part Two. Diagnostic Devices:Part Three. Diagnostic Imaging. Treatment Devices:Part One. Treatment Devices: Part Two. TreatmentDevices: Part Three. Biomedical EngineeringTechnologist (BMET) Work. Testers and Tools.Batteries, Radiation, and Computers. TechnologyManagement. Appendix A: Normal Values. AppendixB: Regulations and Standards. Appendix C:Biomedical Engineering Technology Programs in theUnited States and Canada.

Catalog no. K12781, October 2011, 391 pp.ISBN: 978-1-4398-6058-8, $93.95 / £59.99Also available as an eBook






Forthcoming!

A LaboratoryManual inBiophotonicsVadim BackmanNorthwestern University,Evanston, Illinois, USA

Adam WaxHao ZhangFrom its basic concepts tomore advanced topics and applications, this bookprovides a complete guide to biophotonics. Theauthor offers both descriptive and quantitative per-spectives as well as a comprehensive overview ofmajor areas of research in the field. The text includescoverage of topics such as light tissue interaction,optical instrumentation, microscopic and macroscop-ic tissue imaging, tissue spectroscopy, therapeuticapplications of optics, and molecular imaging.


Catalog no. K10524, September 2013, c. 500 pp.ISBN: 978-1-4398-1051-4, $89.95 / £57.99

Coming Soon!

The Textbook ofNano-neurosurgeryEdited by

Babak KatebCedars Sinai Medical Center,West Hollywood, California, USA

John D. HeissNational Institute of Health, Bethesda, Maryland, USA

Reviewing the state of the nanoneurosurgery field, thisbook provides current information about nanoplat-forms and their use in neurosurgery, neurology, neuro-science and neuroradiology. It focuses on the educa-tional gap across different disciplines, emphasizing theimportance of integrating nanotechnology into clinicalneurosurgery, neurology, neuroscience, and radiolo-gy/medicine. The authors cover currently availablenanoplatforms developed for cancer imaging, drugdelivery and therapeutics as well as traumatic braininjury and neurodegenerative disorders. The text alsoprovides links to online videos illustrating the differentnanoplatforms that are being used in vivo and in vitro.


A LaboratoryCourse in TissueEngineeringMelissa Kurtis MicouUniversity of California, SanDiego, USA

Dawn M. KilkennyUniversity of Toronto, Ontario,Canada

“This book has a protocol-like style and can actual-ly be used directly by teachers to prepare lab cours-es as well as by people with lab experience that enterthe field of tissue engineering. … provides studentswith good insight in methods, techniques andapproaches in the field of tissue engineering.”—Gerjo J.V.M. van Osch, Erasmus MC, University Medical

Center Rotterdam, the Netherlands

"… provides comprehensive coverage of laboratorytechniques in tissue engineering, including detailedexperimental protocols."

—Adam Higgins, Oregon State University, Corvallis


Catalog no. K13694, August 2012, 304 pp., SoftCover, ISBN: 978-1-4398-7893-4, $59.95 / £38.99Also available as an eBook

Bestseller!

Introduction toBioMEMSAlbert FolchUniversity of Washington,Seattle, USA

“The field has been waiting for a true textbook thatprovides a practical, historical, authoritative, andcomprehensive introduction to bioMEMS. It hasfinally arrived, courtesy of Albert Folch, completewith PowerPoint lectures and thoughtful homeworkquestions. I highly recommend it.”

—David J. Beebe, University of Wisconsin–Madison

“Dr. Folch’s book is a monumental achievementwhich brings an authoritative and comprehensiveaccount to the rapidly growing, multidisciplinaryfield of bioMEMS.”

—Mehmet Toner, Harvard Medical School

An instructor's manual is available upon qualifying courseadoption

Catalog no. K10966, August 2012, 528 pp.ISBN: 978-1-4398-1839-8, $89.95 / £57.99Also available as an eBook







25



A LaboratoryCourse inBiomaterialsWujing XianUniversity of Illinois at Urbana-Champaign, USA

A teaching tool for instructors in biomaterials and bio-engineering, this volume is a comprehensive labora-tory textbook. It trains students in laboratory skills,data analysis, problem solving, and scientific writing.It integrates a variety of principles that include mate-rials science, chemistry, biochemistry, molecular andcell biology, and engineering. Providing detaileddescriptions, explanations, and illustrations of experi-ments, the text also includes a series of questions andanswers at the end of each chapter to clarify concepts.Many of the experiments presented are adapted fromresearch papers in biomaterials and bioengineering.

Catalog no. 75829, June 2009, 216 pp., Soft CoverISBN: 978-1-4200-7582-3, $67.95 / £43.99

BiomedicalEngineeringPrinciplesSecond EditionArthur B. Ritter, Vikki Hazelwood, andAntonio ValdevitStevens Institute of Technology,Hoboken, New Jersey, USA

Alfred N. AscioneAlcatel-Lucent Technologies, New Jersey, USA

Integrating engineering, medicine, biology, andphysics, this book clearly defines basic principles inimage processing and biomechanics, modeling phys-iological processes and bioelectric signal analysis tobuild a solid understanding of devices and designs forimproved functioning of the human body. It includescutting-edge discussions of tissue engineering, cardio-vascular components, bone regrowth, and nerveregeneration. Other topics include technologies at theforefront of cardiac care as well as issues related tominimally invasive and robotic surgery, next-genera-tion imaging devices, and nanodevices.


Catalog no. K10621, May 2011, 540 pp.ISBN: 978-1-4398-1232-7, $104.95 / £66.99Also available as an eBook

An Introductionto BiomaterialsSecond EditionEdited by

Jeffrey O. HollingerCarnegie Mellon University,Pittsburgh, Pennsylvania, USA

Series: Biomedical Engineering

The second edition of this popular text includes ninenew chapters that provide a comprehensive and up-to-date educational framework for biomaterials edu-cation. The book explains in vivo and in vitro testingparadigms and provides numerous examples in thechapters on experimental design, laboratory assays,and animal models. Emphasizing the importance ofthe regulatory process, it describes how innovation inthe biomaterials process relates to patentability andinventorship. The text contains end-of-chapter ques-tions and extensive references.

A solutions manual, instructor's manual and figure slides areavailable upon qualifying course adoption


BioMEMSScience andEngineeringPerspectivesSimona Badilescu andMuthukumaranPackirisamyConcordia University, Montreal,Quebec, Canada

Covering often overlooked areas in the field ofbioMEMS, this volume spans topics associated withbiomolecules and complex biological entities, as wellas subjects directly linked to the design, fabrication,and characterization of devices. Unlike other refer-ences, this text aids in the fundamental physiochemi-cal understanding of biological processes relevant tothe performance of various biosensing devices. Usefulfor upper-level undergraduate and graduate studentsenrolled in engineering programs, the book includesproblems in each chapter, in addition to case studiesthat provide real-life examples.



For theLab

For theClassroom







Biomaterials Education Medical Devices

BiomaterialsA Nano ApproachSeeram Ramakrishna,Murugan Ramalingam,T.S. Sampath Kumar,and Winston O. SoboyejoThis book examines basic concepts, various process-ing methodologies, and techniques involved in thepreparation and characterization of nanobiomaterialsthat are specific to biomedical applications. It spanstheir historical development and reviews recentadvances in the field. It describes how basic conceptsin nanotechnology are applied to the processing ofnovel nanobiomaterials, including nanostructuredmetals and alloys. Presenting illustrative examples anda variety of applications, this text offers a solid frame-work for understanding present and future trends ofbiomaterials in human health care systems.

Figure slides are available upon qualifying course adoption

Catalog no. 47817, June 2010, 372 pp.ISBN: 978-1-4200-4781-3, $104.95 / £73.99

Reliable Designof MedicalDevicesThird EditionRichard C. FriesISORel, Inc., Fitchburg,Wisconsin, USA

“This book focuses on an important topic ... thatengineers need to understand in all of its aspects—philosophy, design, and testing and evaluation.They also need to know how they fit in to the largerpicture (manufacturing, packaging, etc…). Thisbook provides both an overview of those facets,along with details to implement them. It is thus avaluable resource for students, researchers, andindustry [professionals] who wish to develop a prod-uct.”—Jon Sensinger, Rehabilitation Institute of Chicago, Illinois,

USA

Following in the footsteps of the bestselling secondedition, this book shows you how to improve reliabil-ity in the design of advanced medical devices. Theorganization of the book now mirrors the typicalproduct development process, from the concept, fea-sibility, and design phases through to verification andvalidation, design transfer and manufacturing, andfield activity. Updated throughout, it reflects recentchanges in the medical device field, including in soft-ware development and hardware test procedures.

• Explains the design process from conception tofield monitoring

• Discusses regulations and standards as well ashuman factors

• Emphasizes safety and risk analysis

• Includes numerous illustrations, tables, sampleforms, checklists of deliverables, references, anduseful appendices

Selected Contents:

The Basics of Reliability. The Concept Phase. TheFeasibility Phase. The Design Phase. Verification andValidation. Design Transfer and Manufacturing. FieldActivity. Appendices. Index.


BiomedicalMicrosystemsEllis MengUniversity of Southern California,Los Angeles, USA

Written by an active researcher named one ofTechnology Review’s Young Innovators Under 35, thisbook begins with an introduction to the benefits ofminiaturization. It introduces materials, fabricationtechnology, and the necessary components of allbioMEMS. The author covers fundamental principlesand building blocks, including microfluidic concepts,lab-on-a-chip systems, and sensing and detectionmethods. The final chapters explore important appli-cations of bioMEMS, such as microdialysis, catheter-based sensors, MEMS implants, neural probes, and tis-sue engineering. Detailed examples, exercises, andillustrations help clarify the concepts.


Catalog no. 51229, September 2010, 408 pp.ISBN: 978-1-4200-5122-3, $99.95 / £62.99Also available as an eBook





27

Medical Devices


New!

The MedicalDevice R&DHandbookSecond EditionEdited by

Theodore R. KucklickTRKD Medical Devices, LosGatos, California, USA

“This is a handbook in the classic sense of the word.It is a concise guide that is directed for those whowant to develop products for the marketplace. …. Iwould say this would serve any professional well,and also be an excellent guide for senior design proj-ects by those students studying biomedical engineer-ing. The information in this book is priceless andrepresents an immense accumulation of practicalknowledge. There is no other text like it.

This is a must read for anyone entering the medicaldevice industry. If you want to make a product—particularly a therapeutic device—you will find nobetter resource than this text. It should be on thebookshelf of each and every biomedical engineer.”

—Brian Wong M.D., Ph.D., University of California–Irvine,USA

• Provides tools for quicker, more efficient development of innovative devices

• Explains the basics of prototyping medicaldevices

• Offers insights on strategic intellectual propertymanagement

• Discusses new rapid-turn molding technologies,medical adhesives, and more

• Includes tips on time- and money-saving techniques

• Contains chapters on starting and building anentrepreneurial business

Selected Contents:

Materials for Medical Device R&D. Processes forMedical Device R&D. Methods for Medical DeviceR&D. Interviews and Insights for the R&DEntrepreneur. Index.


Forthcoming!

BiomedicalTechnology andDevicesHandbookSecond EditionEdited by

James MooreDuncan MaitlandTexas A&M, College Station, USA

Handbook Series for Mechanical Engineering

Fully revised with ten new chapters, this reference illu-minates the equipment, devices, and techniques usedin modern medicine to diagnose, treat, and monitorhuman illnesses. With topics ranging from basic pro-cedures like blood pressure measurements to cutting-edge imaging equipment, biological tests, and genet-ic engineering, the book is organized to navigatesmoothly from simple procedures and concepts tomore sophisticated and complex ones. Each sectioncontains a description of the technique, its technicalconsiderations, and its use according to its applica-tions and relevant body systems.


Forthcoming!

MedicalInstrumentsand DevicesPrinciples andPracticesEdited by

Steven Schreiner,Joseph D. Bronzino, and Donald R. PetersonThis book draws on material from the medical instru-ments and devices section of The BiomedicalEngineering Handbook, Fourth Edition. Edited bySchreiner, Bronzino, and Peterson, this referencebrings together contributions by world-class expertsin the field. Offering comprehensive treatment of thelatest developments and research being conducted inbiomedical instruments and devices, this is a usefulresource for practitioners, scientists, and researchersworking in the areas of medical devices and instru-mentation, as well as graduate students studying bio-engineering, instrumentation, and medical devices.







Medical Devices

Forthcoming!

Devices forMobility andManipulationfor People withReducedAbilitiesTeodiano Freire Bastos-Filho, Dinesh Kumar,and Sridhar Poosapadi ArjunanThis book provides the details of mobility and manip-ulative technologies. It provides an insight into cur-rent research trends and also discusses technologiesthat are under development. Each chapter covers onespecific technology, beginning with a general intro-duction, followed by technical details and an assess-ment from the user viewpoint, including user benefits,user suitability, cost, reliability, and required infrastruc-ture. Each chapter also provides illustrations or photo-graphs of the devices, targeted for lay and clinicalaudiences. It also identifies any shortcomings and pos-sible development opportunities.


UsabilityTesting ofMedical DevicesMichael Wiklund,Jonathan Kendler, andAllison Yale StrochlicWiklund Research & Design, Inc.,Concord, Massachusetts, USA

Informative, practical, and engaging, this handbookcovers how to conduct usability tests of medicaldevices. Recognizing that the intended readers arebusy and disinclined to read lengthy textbooks, thisbook has been carefully designed to be concise andvisual, allowing readers to jump from one section toanother as needed. The book provides a generalunderstanding of usability testing and reviews keyconcepts. It highlights the challenges of validatingthat protect against dangerous errors that could leadto patient injury and death.


ISO 13485A Complete Guide to QualityManagement in the Medical DeviceIndustryItay AbuhavHinterforst, Switzerland

The United States and European Union now requirethe ISO 13485 Standard certification for medicaldevice manufacturers. Written by an experiencedindustry professional, this practical book provides acomplete guide to the ISO 13485 Standard certifica-tion for medical device manufacturing in terms ofquality control. It covers all the requirements of ISO13485 and offers a step-by-step comparison betweenthe ISO 13485 and ISO 9001, enabling a soundunderstanding of the new procedures. It also providesnumerous implementation examples from varioussectors.

Catalog no. K12946, October 2011, 374 pp.ISBN: 978-1-4398-6611-5, $139.95 / £89.00Also available as an eBook

DesigningUsability intoMedicalProductsMichael E. WiklundWiklund Research & Design, Inc.,Concord, Massachusetts, USA

Stephen B. WilcoxDesign Science, Philadelphia,Pennsylvania, USA

This book covers the essential processes and specifictechniques necessary to produce safe, effective,usable, and appealing medical systems and products.Written by experts on user-centered research, design,and evaluation, the book provides a range of alterna-tive approaches. Wiklund and Wilcox explore how tomake medical devices safe and effective by involvingusers in the design process. They discuss specificdesign and evaluation methods and tools, presentcase studies of user-friendly medical technologies andcorporate human factors programs, and supply relat-ed resources for medical design professionals.

Catalog no. 2843, February 2005, 376 pp.ISBN: 978-0-8493-2843-5, $146.95 / £94.00Also available as an eBook






29

Medical Devices Industry Applications


Handbook ofHuman Factorsin MedicalDevice DesignEdited by

Matthew B. WeingerVanderbilt University, Nashville,Tennessee, USA

Michael E. WiklundWiklund Research & Design, Inc.,Concord, Massachusetts, USA

Daryle J. Gardner-BonneauPrincipal, Bonneau and Associates, Portage, Michigan, USA

“... interesting, well-written, and achieves the goal ofraising the reader's awareness of important designissues. I loved the book and now that I've told my col-leagues, they want to read it as well, so we'll buy onefor our library since I'm not giving up my copy!Although it is not intended to provide specific solutionsto design problems, even a reader with experience inequipment design will most definitely gain new insightsinto the man-machine interface of medical devices.”

—Jonathan A Gaev, Biomedical Engineering Online

Catalog no. ER562X, December 2010, 844 pp.ISBN: 978-0-8058-5627-9, $145.95 / £93.00Also available as an eBook

Forthcoming!

Measurement,Instrumentation,and SensorsHandbookSecond Edition (Two-Volume Set)Edited by

John G. WebsterUniversity of Wisconsin, Madison, USA

Halit ErenCurtin University, Bentley, Australia

Series: Electrical Engineering Handbook

Edited by renowned instrumentation experts, thisnew edition of a bestselling handbook brings togeth-er nearly 150 contributors in two volumes, coveringall aspects of the design and implementation of instru-mentation. It describes the use of instruments andtechniques for performing practical measurements inengineering, physics, chemistry, and the life sciences.Organized according to measurement problem, eachsection addresses the different ways of making ameasurement for a given variable. Each chapter iscompletely updated and presents basic information, adetailed mathematical treatment, advanced applica-tions, evaluative options, and areas for future studies.

Catalog no. K12205, October 2013, c. 2700 pp.ISBN: 978-1-4398-4883-8, $249.95 / £159.00Also available as an eBook

Also available as individual volumes

Measurement, Instrumentation,and Sensors Handbook, Second EditionSpatial, Time, andMechanical MeasurementCatalog no. K12208, August 2013, c. 1544 pp.ISBN: 978-1-4398-4888-3, $149.95 / £95.00

Measurement, Instrumentation,and Sensors Handbook, Second EditionElectromagnetic, Optical,Radiation, Chemical, andBiomedical MeasurementCatalog no. K12210, October 2013, c. 1250 pp.ISBN: 978-1-4398-4891-3, $149.95 / £95.00

Individual volumes also available as eBooks

New!

Handbook ofMedical DeviceRegulatoryAffairs in Asia Edited by

Jack WongAsia Regulatory ProfessionalAssociation, Kwun Tong,Kowloon, Hong Kong

Raymond Tong KaiyuHong Kong Polytechnic University, Hung Hom, Kowloon

This handbook covers medical device regulatory sys-tems in different countries, ISO standards for medicaldevices, clinical trial and regulatory requirements, anddocumentation for application. Each chapter providessubstantial background materials relevant to the par-ticular area to have a better understanding of regula-tory affairs. With contributions from authors workingwith regulatory bodies around the world, the hand-book provides a better understanding of the Asianmarket and how to access it. It guides product devel-opers through the global regulatory environment.

Catalog no. N10745, February 2013, 450 pp.ISBN: 978-981-4411-21-9, $149.95 / £95.00Also available as an eBook








Industry Applications

Forthcoming!

MEMSPackaging andTechnologyEdited by

Vikas ChoudharyAnalog Devices, Bangalore,Karnataka, India

Krzysztof IniewskiCMOS Emerging Technologies,Inc., Vancouver, British Columbia, Canada

Series: Devices, Circuits, and Systems

Written by international experts, this book presentsthe latest research in the field of MEMS technologyand the myriad applications that it has enabled. Thetext covers automotive, consumer, communication,and medical applications of MEMs. Some of the appli-cations discussed include high-precision on-chip inte-grated oscillators for reference generations, gyro-scopes in cameras for optical image stabilization, radiocommunication, bio-implantable kidneys, and mobilephones. Other chapters address MEMS packagingand MEMS resonators, providing a fundamentalunderstanding to enable novel applications.

Catalog no. K15054, June 2013, c. 472 pp.ISBN: 978-1-4665-1581-9, $149.95 / £95.00Also available as an eBook

TechnicalWritingA Practical Guide forEngineers andScientistsPhillip A. LaplanteThe Pennsylvania StateUniversity, Malvern, USA

Series: What Every EngineerShould Know

Written by a renowned engineer and widely pub-lished technical author, this guide enables readers towrite, edit, and publish materials of a technical nature,including books, articles, reports, and electronicmedia. Complementing the traditional writer’s refer-ence manuals and other books on technical writing, ithelps readers understand the practical considerationsin writing technical content. Drawing on his ownwork, the author presents many first-hand examplesof writing, editing, and publishing technical materials.These examples illustrate how a publication originat-ed as well as various challenges and solutions.

Catalog no. K11106, July 2011, 250 pp., Soft CoverISBN: 978-1-4398-2085-8, $41.95 / £26.99Also available as an eBook

BiomaterialsFabrication andProcessingHandbookEdited by

Paul K. ChuCity University of Hong Kong,Kowloon

Xuanyong LiuShanghai Institute of Ceramics, China

This volume focuses on a variety of production andprocessing aspects of the latest biomaterials. It dis-cusses how scaffolds are used in tissue engineeringand describes common implant materials. The bookalso examines the important role nanotechnologyplays in the preparation of drugs, protein delivery, tis-sue engineering, cardiovascular biomaterials, hard tis-sue replacements, biosensors, and bioMEMS. Withcontributions from renowned international expertsand extensive reference lists in each chapter, this bookprovides detailed, practical guidance on producingbiomaterials and employing them in biomedicine.

Catalog no. 7973, March 2008, 720 pp.ISBN: 978-0-8493-7973-4, $179.95 / £115.00Also available as an eBook

Contracts forEngineersIntellectual Property, Standards, and EthicsRobert D. HunterRobert D. Hunter Associates,Austin, Texas, USA

Engineers encounter various forms of contracts atnearly every turn in their careers. This book enhancestheir ability to communicate contractual issues tolawyers and then better understand the consequentlegal advice they receive. The text introduces therelated subjects of intellectual property (includingpatents, copyright, trademarks, and trade secrets) andstandards (including conformity assessment andaccreditation) at both the micro and macro levels, aswell as the role of ethics. It also discusses typical termsof employee agreements, as well as information ongovernment contracts.







Don’t Miss Out!

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Biomaterials and Medical Devices