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Page 1 • Biologics - Why What How • September 12, 2015
Forward-Looking Statements
This presentation may contain forward-looking statements based on current assumptions and forecasts made by Bayer Group or subgroup management.
Various known and unknown risks, uncertainties and other factors could lead to material differences between the actual future results, financial situation, development or performance of the company and the estimates given here. These factors include those discussed in Bayer’s public reports which are available on the Bayer website at www.bayer.com.
The company assumes no liability whatsoever to update these forward-looking statements or to conform them to future events or developments.
Biologicals & Integrated Crop SolutionsEltjo Huizengaglobal Segment Manager Biologics
BLX & ICS – 2015
Page 3 • Biologics - Why What How • September 12, 2015
Why Biologicals & what are Integrated Crop Solustions?
Bayer CropScience has many very succesfull chemical products in its portfolio and an interesting product pipeline so why is it interested in Biologicals & what are Integrated Crop Solustions?
Page 4 • Biologics - Why What How • September 12, 2015
Contents Biologics in Integrated crop solution for F&VGrower trends for biological products
How to develop an Integrated crop solution
How to test/present/demonstrate Integrated crop solutions
Page 5 • Biologics - Why What How • September 12, 2015
6,4
6,3
4,7
4,34,1
3,5
1,7
1,4
1,3
1,3
1,30,8
0,73,3
SoybeansCerealsCornVegetablesFruit & NutsRiceCottonOilseed rapeSugar caneGrapesPotatoesPlantationsSugar beetsOthers
11.7 bn €(28.6%)
Source: TriCast 2013
Total40.9 bn €
Global Crop Protection MarketFocus on Fruit & Vegetables
2013 : About 1 in every 3,5 Euros is spent on Horticultural crops globally
Page 6 • Biologics - Why What How • September 12, 2015
Fruit & Vegetables account for the largest share of our portfolio today
€ 2.0 bn2013 sales in F&V
strengthening position towards
F&V market leadership and
aspiring
€ 3.6 bn2020 sales target
Rice
Cotton
Oilseeds
Soy
Corn
Cereals
BCSsales2013*
Diverse crop spectrum:• Fruits & nuts, grapes/vines,
plantations• Vegetables & flowers,
potato
Fruit & Vegetables
* by major crop groups excluding industrial business and non-agricultural solutions
others
Sugar crops
Page 7 • Biologics - Why What How • September 12, 2015
Market Megatrends
Value ChainConsumption
+
Production
Climate variability Competition for water Available farmland Increasing production
and energy costs Techn. evolution
Global sourcing and global trade
Food value chain requirements
Liability of produce Technology
evolution
Population growth Increasing disposable
incomes / rise of the middle class
Urbanization Consumer behavior
+
Increasing need for:• Higher productivity of agricultural production systems through innovation, sustainable technologies
(e.g. mechanization, IPM, hybridization) and improved management practices (e.g. digitalization, integrated crop solutions) while reducing loss and waste
• Close collaboration within the value chain to address trends and for fast technology adoption• Active dialogue with stakeholders to comprehend unmet needs and opportunities
=
Page 8 • Biologics - Why What How • September 12, 2015
“Leadership in Horticulture” is fueled by five strategic Key Enablers
Build innovative portfolio for fruit & vegetable crops
Expand teams of Fruit & Vegetable Experts
Partner and connect players along Food Value Chain
Build Integrated Crop Solutions
Provide innovative and high-quality vegetable seeds
1 2 3 5
4
Strengthen Customer Centricity
Lead the Wayin Innovation
ExpandSeeds Business
EnhanceCrop Protection & Environmental Science
Page 9 • Biologics - Why What How • September 12, 2015
Category What? Example
Microbials
Biorationals
Macrobials
Other
• Bacteria (microbe and/or biochemical) • Fungi
• Plant extracts & essential oils• Pheromones (semiochemicals)
• (Attractants)
• Beneficial insects including predatory nematodes
• Viruses• Cyclic peptides• RNAi*• Gene delivery• Excluding inorganics (like Copper and Sulphur)
Biological Product Categories
* RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression (potentially using microbes as inducer/carrier)
Page 10 • Biologics - Why What How • September 12, 2015
Challenges
• Weed, pest & disease control
• Resistance management
• Worker exposure
• Chemical input
Sustainableintensification of agriculture
Benefits
Across the value chain
• Yield Quantity
• Yield Quality
• Integrated Pest Manage-ment (IPM)
• Tradeability
• Storability / Reduce loses
Contribution to Food Security
• Canola• Cotton• Rice• Soybean• Wheat• Vegetables
• Disease control• Pest control• Plant Health• Nutrition
efficiency
• Herbicides• Fungicides• Insecticides• Seed treatment
Higher yieldHigher qualityConvenience
Risk management
GROWERDEMAND
• On-field consulting
• Training• Diagnostic
tools
Focusing on Customer needs
Page 11 • Biologics - Why What How • September 12, 2015
0
1
2
3
4
5
6
2005 2010 2015 2020 2025
Microbials
Biorationals
Macrobials
Source: Frost & Sullivan, Nov. 2009; BCC Research Survey 2010; CPL Business Consultants 2010
bn $Short term (<3 years) Food Chain demands Sustainable Use Directive EU New Biological product introductions Country low chem programs (e.g. F)
Mid term (>5 years) Increasing demand for Biological solutions
in emerging markets (Brazil, China and India)
Sustainable growth of Biological solutions in the US and EU
Investments BASF, Syngenta, Bayer
Long term (>10) Introduction of new Biological technologies
• Average Market Growth (2005-2025): > 10 % Biologicals vs. Chemical < 3% CAGR• Biologicals Market (2010-2020): 1.2 – 3.7 bn. US$
Biologicals are in demand!
Page 12 • Biologics - Why What How • September 12, 2015
Category What? Example Market approach
•Bacteria (microbe and/or biochemical) •Fungi
•Plant extracts & essential oils•Pheromones (semiochemicals)
•(Attractants)
•Beneficial insects including predatory nematodes
• Viruses• Cyclic peptides• RNAi*• Gene delivery• Excl. inorganics (like Copper and Sulphur)
Biological Product Categories & BCS focus
* RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression (potentially using microbes as inducer/carrier)
Microbials
Biorationals
Macrobials
Other
invest to lead
exploitopportunities
partnering
evaluate opportunities
Page 13 • Biologics - Why What How • September 12, 2015
Why do Biologicals fit so perfectly into our portfolio?
SolutionThinking
ProductThinking
Because they fit perfectly in
Integrated Crop Solutions i.e.
solutions that help farmers to
address unmet cropping needs
(needs that they cannot fulfil with
conventional methods)
Page 14 • Biologics - Why What How • September 12, 2015
Our basis to build on - excellent pipeline for Fruit & Vegetable crops
Chemicals
Seeds
Biologicals
Integrated crop solutions
• Improved ROI• Higher yield• Supreme quality• Convenience• Risk management
Grower benefits
• Alion™
• Movento™
• Sivanto™
• Luna™
• Emesto™
• Velum ™
• 700 new varieties in 10 vegetable crops until 2016
• Serenade™
• Sonata™
• Requiem™
• BioAct™
Page 14
Page 15 • Biologics - Why What How • September 12, 2015
Integrated Crop Solutions are offers of any combination of Seeds, Traits, Chemicals and Biologicals with Services thatare tailored towards the needs of our target customers and create sustainable value for them, the value chain and BCS
What areIntegrated Crop Solutions (ICS)
Chemical
Services / Tailored advice
Seed Trait Biological
Page 16 • Biologics - Why What How • September 12, 2015
With (biologicals in) Integrated Crop Solutions,farmers will be able to address unmet needs
Potential unmet needs* Enabling Global Trade (residue management)
Sustainable Cropping
IPM / ICM compatible (e.g. safe for beneficials)
Extending shelf life / reducing losses
Compete some difficult pests/ diseases (e.g. thrips, bacteria, nematodes, etc.)
Yield increase (quality & quantity)i.e. plant health/yield enhancement
Resistance Management
Low chemical input
Flexibility in use (low REI or PHI)
Worker exposure
SolutionThinking
ProductThinking
* different unmet needs can also be addressed with chemical
Page 17 • Biologics - Why What How • September 12, 2015
For Integrated Crop Solutionsa Biological portfolio is neededPortfolio today
Product Microbe/Extract Reg. & Distribution
NA AP LA EU
VoTiVo and Flocter (BioNematicide SGr) Bacillus firmus I-1582 X X
Dipel and Xentari (BioInsecticide) Bacillus thuringiensis Kurstaki & Azawai XTP XTP
Bio1020 (soil) (BioInsecticide) Metarhizium anisopliae Met52 XTP
Kodiak (BioFungicide SGr) Bacillus subtilus GB03 X
Serenade (BioFungicide) Bacillus subtilus QST713 X X X X
Sonata (BioFungicide) Bacillus pumilus QST2808 X X
Requiem (BioInsecticide) Blend of 3 terpenes X X X
Contans (BioFungicide) Coniothyrium minitans CON/M/08-91 X X X X
BioAct (BioNematicide) Paecilomyces lilacinus 251 X X X
Esquive (BioFungicide) Trichoderma atroviride I-1237 XTP
Charane CM-F/OFM-F (BioInsecticide) Codlemone (pheromones) XTP XTP XTP XTP
Decis Trap (attract & kill) (BioInsecticide) Deltamethrin + attractant(s) X
Optimize 200 (inoculent) Rhizobium XTP
Biagro 10 (inoculent) Rhizobium X
more countries
more crops
TP = Third party
Page 18 • Biologics - Why What How • September 12, 2015
Contents Biologics in Integrated crop solution for F&V
Grower trends for biological productsHow to develop an Integrated crop solution
How to test/present/demonstrate Integrated crop solutions
Page 19 • Biologics - Why What How • September 12, 2015
Drivers & Barriers to use biologicals
Not
e: b
ased
on
252
in d
epth
inte
rvie
ws
in 1
5 co
untri
es o
n 11
cro
ps
Page 20 • Biologics - Why What How • September 12, 2015
Usage will increase as biologicals get integrated into spray programs
Page 21 • Biologics - Why What How • September 12, 2015
Farmers say they would use biologicals for its
More than efficacy only!!!
Note: in total 7 interviews per country per crop
Page 22 • Biologics - Why What How • September 12, 2015
Farmers say they would use biologicals for
Note: in total 7 interviews per country per crop
Page 23 • Biologics - Why What How • September 12, 2015
Contents Biologics in Integrated crop solution for F&V
Grower trends for biological products
How to develop an Integrated crop solutionHow to test/present/demonstrate Integrated crop solutions
Page 24 • Biologics - Why What How • September 12, 2015
Integrated Crop Solutions are offers of any combination of Chemicals and Biologicals supported by Services that are tailored towards needs of our target customers and create sustainable value for them, the value chain and BCS
Chemical
Services / Tailored advice
How to integrate Biologicals inIntegrated Crop Solutions (ICS)
Chemical Biological Biological
Page 25 • Biologics - Why What How • September 12, 2015
09Green
leaf tips
57 Pink bud
stage
60 - 65 First
flowersopen/Fullflowering
72 Fruit sizeup to 20
mm
74 Fruit
diameter up to 40 mm; fruit erect
81
Ripening
87
Ripening
pre and post harvest application disease control and residue management
Conventional CPPDriver: reduce residue level
Integrated Crop Solution (ICS)
Biological
BiologicalConventional Conventional
Positioning of Biologicals in ICS (example)
Driver: alternation for resistance managementor safe use during flowering
Page 26 • Biologics - Why What How • September 12, 2015
*not approved until 2016
Applied near plant with new root flush- 9,4 l / ha in chemigation
1)
1) Serenade™ is a versatile product that can be used to control various fungi and bacteria giving also a plant enhancement/yield effect
Improved performance / ResistanceStrawberries in USA (Soil diseases, Botrytis & PM)
1) 1)
Sales
Powdery mildew& Botrytis
Powdery mildew& Botrytis
Powdery mildew& Botrytis
Botrytis Powdery mildew
Verticillium & Plant Health
DRIVERS for use of Serenade1. Improved performance on soil diseases & plant health2. Resistance management (Botrytis & PM)3. Workforce management at harvest time (short REI/PHI)4. Yield increase
Page 27 • Biologics - Why What How • September 12, 2015
Flexibility and sustainabilityTable grapes in Chile (disease control)
DRIVERS for use of Serenade1. Prevent infection 2. Alternate modes of action / resistance management3. Global trade i.e. residue management and PHI
Sales
Page 28 • Biologics - Why What How • September 12, 2015
Improve performancePommes fruits in Spain (fire blight)
Program:• Pre-flowering: copper (250 g Cu/hl)• Flowering: Serenade MAX / Aliette. 3-7 days interval or under alert system advise• Full vegetative development (summer): Aliette 24 hours after a storm.• Autumn/Winter: copper (250 g Cu/ha) 2 treatments after leaves fall
DRIVERS for use of Serenade1. Prevent infection of bacterial disease (Fire Blight / Erwinia amilovora)
2. Less Chemical load / replacement of antibiotics
Cuprosan Cuprosan+
Sales
Page 29 • Biologics - Why What How • September 12, 2015
Reduce losses / Global trade Apples in Brazil (foliar disease & fruits rot)
30 – 40 days 1-2 days20 days 14 days
&&
7 days
DRIVERS for use of Serenade1. Reduce losses (pre-harvest disease control with post-harvest effect)
2. Global trade i.e. residue management and PHI
days before harvest
Sales
Page 30 • Biologics - Why What How • September 12, 2015
Soil Application Foliar Application Residual treatment Pre-Planting Post-Planting
OptionalPost Harvest
DRIVERS for use of Contans1. Improved and long lasting performance by specific pre- and post-harvest
use of Contans and in-season use of Luna and Serenade2. Enabling cropping in high infested fields3. Reduce losses (in field & in storage)4. Treatment outside of high work peak period
Performance / Global tradeLettuce in various countries (Sclerotinia spp. control)
Fungicide
Sales
Page 31 • Biologics - Why What How • September 12, 2015
Soil Application Foliar Application Residual treatment Pre-Planting Post-Planting
OptionalPost Harvest
DRIVERS for use of Contans1. Improved and long lasting performance by specific pre- and post-harvest
use of Contans and in-season use of Luna and Serenade2. Reduce losses (in field & in storage)3. Treatment outside of high work peak period
Improve performance / Global tradeOSR in various countries (Sclerotinia spp. control)
FungicideFungicide
Sales
Page 32 • Biologics - Why What How • September 12, 2015
DRIVERS for use of Contans1. Improved and long lasting performance2. Enabling global trade (residue reduction)3. Reduce losses (in field & in storage - pre-harvest treatment with post harvest effects)
Performance / Global tradeRed Currant in N-EU (disease control)
Page 33 • Biologics - Why What How • September 12, 2015
Improved performancePotatoes in USA (soil diseases*)
pre-row closureend of June 1st JulyJune 15Planting
10-14 days
10-14 days
10-14 days
10-14 days
Seed treatment10-14 days
4,6 l/hectare in furrow
4,6 l/hectarechemigation
DRIVERS for use of Serenade1. Improved performance on soil diseases (Rhizoctonia solani and Phytophthora erythroseptica)
2. Reduce losses (pre-harvest disease control with post-harvest - e.g. pink rot - effect)
3. Increase yield
*
*
* key soil diseases like Rhizoctonia, Fusarium, Pythium and Phytophthora (Pink rot)
Sales
Page 34 • Biologics - Why What How • September 12, 2015
seed planting harvesting---------------------------- growing -----------------------
White flies/aphids White flies/aphids
Flexibility and sustainability (PHI / REI)Leafy vegetables e.g. in MEX (white fly & aphids)
DRIVERS for use of Requiem1. Flexibility (REI, PHI and wide application window)
2. Residue management 3. Worker exposure
Sales
Page 35 • Biologics - Why What How • September 12, 2015
Improve performance by synergyPotatoes in Texas, USA (Psyllid & Zebra Chip)
70
Tuber development
80
MaturationBulking-up
90
Senescence
30
Main stem elongation
40
Tuber formation
50
Flower emergence
60
Flowering
0 10
Emergence
20
Stem formation
2 applications
7-10 days
ADMIRE PRO
Presumed, primary ZC “infection” window Psyllid control window
1-2 applications
7-10 days
abamectin1 application each
or tank-mix
7-10 days
adult KDif needed PH
7-10 days
DRIVERS for use of Requiem against Psyllids1. Improves performance on a difficult to control insect2. Resistance prevention (alternation program)3. Synergistic effect (knock-down - Requiem & residual compounds - Keteonols)4. Fit in IPM program (treatment following monitored flight of adults)
Planting
Page 36 • Biologics - Why What How • September 12, 2015
seed planting floweringgrowth ---------------------------- harvesting period -----------------------fruiting
nursery 0 30 60 DAT10 20 40 50
Improved performanceCucumber in Spain (thrips)
Amblyseius swirskii 50 A. swirskii/m2 (repeat 12 weeks later 50 A. swirskii/m2)
MAIN THRIPS INFESTATION PERIOD
DRIVERS for use of Requiem against thrips1. Improves performance on difficult to control insect(s)2. Safe on beneficials / compatible in IPM programs3. Flexibility (short PHI, short REI, wide application window, multiple sprays, etc.)4. Resistance prevention
Page 37 • Biologics - Why What How • September 12, 2015
JAN DECFEB MAR APR MAY JUN JUL AUG SEP OCT NOV
FloweringShooting BuddingSucker Development Ripening
Innovative & sustainable approachBananas in CR (nematodes)
DRIVERS for use of BioAct against nematodes1. Higher yield when used in alternation2. Excellent safety profile 3. Lowers annual chemical load significantly4. Residue management5. Healthier plant due to increased functional roots 6. Increase sustainability
Sales
drench / granular
Radopholus similis, Helicotylenchus spp., Pratylenchus spp.
Harvest
Page 38 • Biologics - Why What How • September 12, 2015
floweringStart - - - - - - - - - - - - - - - - - - - harvest - - - - - - - - - - - - - - - - - - -fruitset
If mildew present: alternation with Vivando or Fungaflor
If Botrytis present:Alternation with Teldor/Switch
Improved performanceCucumbers in Northern Europe (powdery mildew)
DRIVERS for use of Serenade1. Resistance management Luna2. Flexibility (wide application window + low PHI)3. Minimizing residue 4. Fit in IPM program (pollinator & beneficial safety )
/ /
Page 39 • Biologics - Why What How • September 12, 2015
DecJan Feb Mar Apr May Jun Jul Aug Sept Oct Nov
Followed by:
Meltatox&
Followed by:
Meltatox&
SwitchKarma Rocket
&Meltatox
& Collis
Rocket &
Karma Followed by:
Meltatox&
Followed by:
Meltatox&
SwitchMeltatox&
Collis
Preventing resistance developmentRozes in the Netherlands (powdery mildew)
DRIVERS for use of Serenade1. Resistance management (alternation of a.i.´s)
Page 40 • Biologics - Why What How • September 12, 2015
Contents Biologics in Integrated crop solution for F&V
Grower trends for biological products
How to develop an Integrated crop solution
How to test/present/demonstrate Integrated crop solutions
Page 41 • Biologics - Why What How • September 12, 2015
Integrated Crop Solutions are offers of any combination of Chemicals and Biologicals supported by Services that are tailored towards needs of target customers and create sustainable value for them, the value chain and BCS
Tailored advice = communication & information, training, demonstration and promotion (aligned with farmers & chain partners)
How to advice/promote/presentIntegrated Crop Solutions
BiologicalBiologicalChemical Chemical
Page 42 • Biologics - Why What How • September 12, 2015
Farmers say they don’t use biologicals because of
Note: in total 7 interviews per country per crop
Page 43 • Biologics - Why What How • September 12, 2015
Farmers say they don’t use biologicals because of (perceived)
= a misconception largely based on assumed stand-alone performance
Note: in total 7 interviews per country per crop
Page 44 • Biologics - Why What How • September 12, 2015
Standalone Efficacy= season long spray• Shows that the BLX does
have some control• Needed for registration
purposes• Not what will be ultimately
marketed
Performance of ICS= integrated in spray program• Identify unmet needs in crop• Create spray program to
meet unmet needs• Measure performance of ICS
with SMol and BLX
Value Proposition of ICS= real solution offer• Measure value proposition –
residues; quality; yield• Measure profitability / ROI• Launch / market the benefits
of the ICS
Time
Marketability of our offer
Moving from product positioning to ICSFrom standalone efficacy to spray programs to value proposition trials
Page 45 • Biologics - Why What How • September 12, 2015
Value proposition of biologics – efficacy is only one criteria illustrative
Applications Programs
A Teldor Luna Privilege Teldor Teldor Luna
PrivilegeLuna
Privilege Serenade
B Teldor Teldor Serenade Serenade Serenade Serenade SerenadeC Serenade Serenade Serenade SerenadeD Serenade Serenade
Efficacy
medium disease
pressure ++++ ++++ +++ ++++ ++++ ++++ ++
highdisease
pressure +++(+) ++++ +++ +++ +++ +++(+) +
The right positioning in a BCS spray program is a key success factor for biologics
Provide efficacious performance on
targeted proposition and control of pests
and diseases
Understanding of relevant value
propositions and transfer into BCS spray programs
Page 46 • Biologics - Why What How • September 12, 2015
0
10
20
30
40
50
60
70
80
90
15 DA-A 13 DA-B 7 DA-C 14 DA-C 14 DA-D 7 DA-E 5 DA-F 13 DA-F 6 DA-G 13 DA-G
% L
eaf S
ever
ity
UTC Standard Program SERENADE Program Skipped Applications
Fischer, Columbia Ag Research, Hood River, OR – 2010. Materials were applied using a CO2 handgun sprayer equipped with one D6 hollow cone nozzle per row delivering 70-180 GPA at 100 psi. Flint 1.5oz at ACF; Quintec 5floz at BD; Procure 6floz, Serenade Optimum 1lb, or no applications at EG. A = 5/19, B = 6/3, C = 6/16, D = 6/30, E = 7/15, F = 7/29 and G = 8/12. Erysiphe necator.(10-06-509)
a
ccd
b
1st SERENADE App. 2nd SERENADE App.
A TrifloxystrobinB QuinoxyfenC TrifloxystrobinD QuinoxyfenEF TrifloxystrobinG
A TrifloxystrobinB QuinoxyfenC TrifloxystrobinD QuinoxyfenE SERENADEF TrifloxystrobinG SERENADE
A TrifloxystrobinB QuinoxyfenC TrifloxystrobinD QuinoxyfenE TriflumizoleF TrifloxystrobinG Triflumizole
Demonstrate ICS benefitsin specially adjusted comparative trials
Disease control in grapes comparing an integrated program to a chemical program
Demonstrate contribution of BLX on efficacy via “blank sprays”
Sales
Page 47 • Biologics - Why What How • September 12, 2015
Show disease control & residue levelFlint, Teldor & Serenade in (small) tomatoes
05
101520253035404550
Control FT/FT/FT FT/Ser/Ser FT/X/X0DAC 7DAC 14DAC
% disease severity
NL: trial number 13906 (2013)
F = 0,0125% Flint Ser = 8L/ha Serenade ASOT = 0,1% Teldor X = no application
0
0,5
1
1,5
2
2,5
3x FT FT/Ser/Ser FT/X/X1DAC 3DAC 7DAC 14DAC 21DAC
MRL fenhexamid = 1 mg/kg
MRL
mg/kg fenhexamid
50% MRL
30% MRL
mg/kg fenhexamid1. Demonstrate contribution of BLX on efficacy via “blank sprays”
2. Demonstrate ICS value proposition
reduction of residues
Page 48 • Biologics - Why What How • September 12, 2015
1
0,45
0,22
0,33
0,94
0,33
0,13
0,82
0,67
0,54
0,110,15
0,93
0,51
0,16
0,39
0,5
0,3
0,090,15
0,54
0,28
0,08
0,32
0
0,2
0,4
0,6
0,8
1
1. T/T/T/S 2. T/T/S/S 3. T/S/S/S 4. T/S/T/S 5. S/T/T/T 6. S/T/T/S 7. S/T/S/S 8. S/T/S/T
1 Day after last applcation 7 days after last applcation 14 days after last applcation
Residues in mg/kg, MRL fenhexamid = 1 mg/kg
Show residue levelfenhexamid in protected tomatoes
MRL
50% MRL
30% MRL
T = TeldorS = Serenade
NL residue trial 2013
Demonstrate ICS value proposition
reduction of residues
Page 49 • Biologics - Why What How • September 12, 2015
Show residue levelCalypso + Requiem in protected tomatoes
Residues in mg/kg, MRL thiacloprid = 0,5 mg/kg
0
0,1
0,2
0,3
0,4
0,5
1. C/C/C/R 2. C/C/R/R 3. C/R/R/R 4. C/R/C/R 5. R/C/C/C 6. R/C/C/R 7. R/C/R/R 8. R/C/R/C
1 Day after last applcation 7 days after last applcation 14 days after last applcation
C = CalypsoR = Requiem
MRL
50% MRL
30% MRL
NL residue trial 2013
Demonstrate ICS value proposition
reduction of residues
Page 50 • Biologics - Why What How • September 12, 2015
Reduce losses / Increase efficiencyPeaches in Spain
-150
-100
-50
0
50
100
UTC Program w/oSerenade
Program w/ Serenade
100 100 100
-28-8
-85
-44
-10
Loss post-harvest
Loss at harvest
Total production for consumption
213 kg 152 kg 110 kg Production needed tomeet 100 kg of demand
47% 66% 91% Production Efficiency %
6 Days before harvest
Demonstrate ICS value proposition
Less post-harvest waste
Page 51 • Biologics - Why What How • September 12, 2015
Untreated SERENADE95%
100%
105%
110%
115%
In-furrow applications of SERENADETM Fungicide increase yield
• Good disease control and positive
growth effects, best illustrated with
the control of Verticillium wilt
• Growth effects are observed
in root & plant size and yield
• Results are independent of
strawberry variety
• Application demonstrated crop
safety to all varieties tested
Performance and yield increaseStrawberries in the US (soil disease control)
Cen
tral C
A, G
row
er D
emos
201
4
root
&pl
ant s
ize
yiel
d
Sales
Page 52 • Biologics - Why What How • September 12, 2015
-25%
-15%
-5%
5%
15%
25%
35%
45%
55%
65%
Soil disease control (Serenade SOIL)Potatoes in USA
9,5% yield improvement over standard (average)with yield improvement in 75% of the cases
Standards include Maxim, azoxystrobin, Ridomil, phosphite, PCNB, Monceren, Sportak, Tecto, Rizolex, Moncut and Ranman
% y
ield
vs.
sta
ndar
d
Sales
Page 53 • Biologics - Why What How • September 12, 2015
Lasting control of bacterial spotRed pepper in Korea with Serenade MAX
0 1 2 3 4
0 1 2Long lasting efficacy on clayx was seen
Rating: Disease Area on calyx0 = No disease1 = Less than 5% 2 = 5.1% to 20 % 3 = 20.1 % to 50% 4 = Greater than 50%
Serenade MAX(x500)
Untreated
Sales
Demonstrate ICS value proposition Quality and yield
Page 54 • Biologics - Why What How • September 12, 2015
Demonstrate the Value Proposition of ICSQuality & Profit - Potatoes in Turkey (Rhizoctonia solani, yield & quality)
Demonstrate ICS value proposition Quality and yield
Sales
Page 55 • Biologics - Why What How • September 12, 2015
Services / Tailored advice
SUMMARY / GUIDELINE1. Understand unmet needs of farmers & value chain partners and define
the value proposition that addres the unmet needs2. Develop* an ICS based on the proposition an design trials accordingly3. Demonstrate/present/communicate the ICS trial results Then the pieces of the puzzle will begin to match
Chemical BiologicalTrait
Integrated Crop Solutions (ICS)
Seed
* preferably jointly with market partners like the Food value Chain
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Biologicals are key drivers for ICS
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Back up slides
Page 58 • Biologics - Why What How • September 12, 2015
Integrated Solution for Disease ControlOSR – France (DuPont partnership)
Page 58
DRIVERS for use of co-pack with BALLADTM
1. Meet EcoPhyto 2018 (France) reduced chemical requirements2. Maintain disease control3. Maintain/improve yield
% Control - Disease Severity
Equivalent control with ½ rate of
chemical
Equivalent control with ½ rate of
chemical
104
106
108
110
112
114
116
118
120
122
124
ACANTO250gai
Ballad 2L ACANTO +Ballad
125gai+1L
% UTC
Yield
Equivalent yield with ½ rate of
chemical
• Serenade Update • December 2014
Sales
Page 59 • Biologics - Why What How • September 12, 2015
or
orSwitch
DRIVERS for use of Contans1. Improved and long lasting performance by specific pre- and post-harvest
use of Contans and in-season use of Luna and Serenade2. Resistance management (alternation or mix with systemic chemistry)3. Enabling global trade (reducing residues)4. Reduce losses (in field & in storage)
Performance / Global tradeBeans in various countries (Botrytis & Sclerotinia control)
Page 60 • Biologics - Why What How • September 12, 2015
Our Portfolio: Serenade™
Active: spores from the bacterium Bacillus subtilis strain QST 713 + natural anti-fungal, anti-bacterial and growth promoting chemistry
Crops: fruits, vegetables, potatoes, ornamentals, oilseed rape, pulses and various other broad acre crops
Registrations: in more than 35 countries worldwide
Pest / disease spectrum: broad spectrum efficacy on various fungi(e.g. Botrytis and Alternaria), bacteria, growth promoting & plant activating
Product category: prophylactic BioFungicide/Bactericide
“Mode of action”: disrupt the cell membrane of the pathogen resulting in a physical breakdown (FRAC 44)
Main formulations: WP (MAX and OPTI) and SC (ASO and SOIL)
Key benefits: very stable, broad spectrum product with foliar and soil contact/protectant activity, proven yield increase, no resistance risk, no residue, excellent root colonizer
Page 61 • Biologics - Why What How • September 12, 2015
Our Portfolio: Requiem™
Active: blend of 3 natural plant-derived terpenes modeled after a plant extract of Chenopodium ambrosioides near ambrosioides
Crops: wide range of protected/glasshouse and field fruits and vegetables, potatoes, some row crops, plantations and ornamentals
Registrations*: USA, Mexico, Israel
Pest / disease spectrum: control of sucking pests, especially thrips, whiteflies, mites & aphids
Product category: knock down BioInsecticide
“Mode of action”: degrades the soft insect cuticle, disrupts insect mobility and respiration + anti-feeding properties + vapor activity
Main formulations: EC
Key benefits: knock down efficacy, non-specific MoA (no resistance), safe for beneficials,flexible use rates, multiple applications possible and flexible timing (now PHI and low REI)
*Status: February 2013
Page 62 • Biologics - Why What How • September 12, 2015
Our Portfolio: BioAct™
Active: spores from the fungus Purpureocillium lilacinum strain PL 251 (synonym for Paecilomyces lilacinus)
Crops: banana, citrus, nuts, peach, grapevine, coffee, ornamentals, fruiting vegetables, carrots, peanuts, cotton, potato, tobacco, turf
Registrations*: in 14 countries worldwide
Pest spectrum: e.g. Meloidogyne, Pratylenchus, Heterodera, Radopholus, Globodera, Rotylenchulus, Tylenchulus
Product category: nematode control product
“Mode of action”: parasitism (feeding on body content) of all stages of common plant parasitic nematodes (esp. larvae and eggs)
Main Formulations: WG, WP, DC Liquid
Key benefits: Broad spectrum product for management of various nematodes(the only known nematicide with a direct effect on egg-stages) + yield increase
Page 63 • Biologics - Why What How • September 12, 2015
Our Portfolio: Contans™WG
Active: Spores from the fungus Coniothyrium minitansstrain CON/M/91-08
Crops: Fruits & vegetables, oilseed rape, sunflower, pulses and various others
Registrations*: in more than 30 countries worldwide
Disease spectrum: Sclerotinia sclerotiorum, Sclerotinia minor and Sclerotinia trifoliorum
Product category: Fungicide
“Mode of action”: parasitism of mycelium and sclerotia of Sclerotinia spp.
Main formulations: WG
Key benefits: Reduces inoculum sources in the soil before it can cause disease; Lettuce: Best known control agent against Sclerotinia sclerotiorum