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kinase transformation ; retrovirus vectors ; mammary tumor virus promoter; long terminal repeat; adeno- virus expression vectors; Herpes simplex virus vec- tors: origin of replication, amplicon; prophage Iz vectors: integration into E. coli chromosome.]

M. Honjo (Organizer): Fourteenth Symposium on Nucleic Acid Chemistry (held in Tokushima, Japan, Oct. 30-Nov. 1, 1986), Nucleic Acid Symposium Series No. 17, IRL Press, Oxford and Washington DC, 1986, vi + 232 pp. ($49; P 27). ISBN l-85221-003-6.

[The proceedings comprise 60 papers by 235 authors on corntemporary research on chemistry of nucleic acids; chemical organic synthesis of nucle- osides and nucleotides; novel reactions of S-bromo- uracil derivatives ; oxidation of pyrimidines ; deuterated nucleosides; griseolic acid derivatives; phosphorylation of AMP; synthesis of oligodeoxy- nucleotides (use of: phosphorothioates; unprotected nucleosides; polymer support; cellulose acetate functionalized with a spacer; 2-(2-pyridil)ethyl group; prebiotic synthesis of nucleic acids; synthesis of T4 endonuclease V gene; purification of oligo- nucleotides ; cloning of genes coding for: rat PCNA/cyclin, canine cardiac phopholamban, hu- man tumor necrosis factor, c-Ha-ras; mutagenesis; autoparasite agents; misreading of S-hydroxydeoxy- guanosine-containing DNA; cleavage of DNA by: complexes of cytochrome P-450, modified bleomycin, Fe(II)-bleomycin; elongation factor EF-3; 4-thiouridine; phosphoseryl tRNA; effect of Evans blue on DNA polymerases; effect of ricin and toxic lectins on eukaryotic ribosomes; analysis of promoter sequences; tRNA-protein interactions; ColEl DNA; 5S ribosomal RNA; fluorescence and quenching; NMR studies on I operators and restric- tion sites; structure of a cyclonucleotide hexamer.]

F.A. Jumak and A. McPherson (Eds.): Biological Macromolecules and Assemblies. Vol. 1: Virus Structures. John Wiley, New York 1984. ix + 397 pp. ($69.95) ISBN o-471-87077-3 (v.1).

(1: Overview: capsid protein, nucleic acid, capsid stabilization, protein-RNA interactions, particle assembly; 2: Southern bean mosaic virus group: vii-ion stability, assembly, nucleic acid; 3: Bromo- viruses ; 4 : Tymoviruses ; 5 : Other viruses : cucumber mosaic virus group, alpha mosaic virus; tomato bushy stunt virus, cowpea mosaic virus; 6: Con- clusions.)

F.A. Jurnak and A. McPherson (Eds.): Biological Macromolecules and Assemblies. Vol. 2. Nucleic Acids and Interactive Proteins. John Wiley, New York, 1985 ($74.95) ISBN o-471-87076-5

(22 contributors; 10 articles. A-form of DNA; base sequence, helicity, hydration and stability of B-form of DNA; Z-form of DNA; kink-antikink; Cro repressor; phage A operators; catabolite acti- vator; gene 5 protein of bacteriophage fd; pancreatic RNase; aminoacyl tRNA synthetases; helix com- parison tables.)

S. Karlin and E. Nevo (Eds.): Evolutionary Processes and Theory. Academic Press, Orlando, FL, 1986 (Proceedings of the Workshop held in Israel in March, 1985). x + 786 pp. ($62.50 cloth; $34.50 paperback) ISBN 0-12-398760-1/1-X.

(42 contributors; 33 articles. Evolutionary prob- lems of molecular biology: gene regulation, tran- scriptional control signals, ribosome gene controls, influenza virus evolution, intermediate filament pro- teins, antigen-binding pockets, major histocompati- bility complexes, immune system evolution. Tempo and mode of molecular evolution: hybrid dysgenesis, non-Darwinian novelties, multigene families, mole- cular clock. Sequences of DNA and proteins: chloroplast DNA, substitutions in coding, nucleotide substitutions, relation of humans to apes. Specia- tion: sexual selection, allopatric and non-allopatric speciation, adaptive speciation, host fidelity, macroevolution. Population genetics : phylogenetic relationships of mitochondrial DNA, ecobehavioral genetics of Drosophila, evolutionary genetics of HLA, polygenic mutations, random genetic drift, Gaussian analysis, instability and cycling, restriction-modifi- cation immunity, altrinistic behavior, evolution of learning, endosperm evolution in higher plants, asexual populations.)

E.F. Keller: A Feeling for the Organism - The Life and Work of Barbara McClintock. W.H. Freeman, New York, 1983, xv + 235 pp. ($17.95 hard bound, $8.95 paperback) ISBN O-7167-1433-7; ISBN 0-7167-1504-X.

(A biographical account of the life and works of Barbara McClintock: preface, historical overview; becoming a scientist; a career for women; 1936-1941: University of Missouri; Cold Spring Harbor; transposition; molecular biology; trans- position rediscovered; a feeling for the organism; notes; glossary.)