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25.0%

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2005 2006 2007 2008 2009

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GDP Growth 2005-2009Percentage Growth from 2005

Baltimore BioHealth US BioHealth

US Private IndustryBaltimore Private IndustrySource: Bureau of Economic Analysis

1 E. Pratt Street, Suite 200, Baltimore, MD 21202 | 410.468.0100 | 888.298.4322 | www.greaterbaltimore.org

biohealthThe Baltimore-Washington region is among the top 5 BioHealth hubs in the US, based on employment, number of firms and venture capital investment.

No.1 in ResearchGreater Baltimore / Central Maryland is home to the nation’s #1 research university (Johns Hopkins), the University of Maryland, NIH, and major university bioparks, making the region the world’s largest hub for medical research and discovery. Baltimore received over $800 million from the NIH in 2012 alone.

Growing Bio BaseThe region ranks 2nd for concentration of BioHealth professionals. Over 85% of local biotech firms and activities are located in the Maryland portion of the Baltimore-Washington region. Greater Baltimore’s BioHealth industry has grown significantly faster than the US BioHealth industry and other private industries.

Bio MegalopolisThe Northeast US corridor from Washington to Boston has the highest concentration of BioHealth firms and employment in the world – larger even than California.

NIH Awards to All Institutions (2012)

Rank University Total Awards

1 Johns Hopkins $606,763,376

2 Cal - San Francisco $500,437,073

3 Michigan $456,305,212

4 Pennsylvania $454,975,727

5 Washington $442,509,710

39 MD - Baltimore $157,607,639

123 MD - College Park $38,201,955

267 MD - Baltimore County $8,406,801

BioHealth Employment Concentration25 Largest US Metros

2011

Rank Metro Area LQ

1 Boston 1.28

2 Baltimore* 1.22

3 Washington, DC 1.21

4 New York 1.20

Baltimore/CMD* 1.14

5 Detroit 1.12

6 San Francisco 1.11

7 Philadelphia 1.10

8 Tampa 1.08

9 Pittsburgh 1.07

10 San Diego 1.07

Megalopolis:

• Washington, D.C. Boston: 442 miles• San Diego San Francisco: 502 miles

Total Bioscience Employment (2011)

North East US 2,382,040California 1,166,974

Percent of All US Venture Capital Funding for Biotech (2003 to 2012)

North East US 38.6%California 40.9%

Rest of US 20.4%

BOSTON / WORCESTER /MANCHESTER CSA

NEW YORK / NEWARK /BRIDGEPORT CSA

PHILADELPHIA / CAMDEN /VINELAND CSA

WASHINGTON / BALTIMORENORTHERN VIRGINIA CSA

Source: County Business Patterns, 2011*Includes Cecil County

› The Washington-Baltimore area is 6th in the US in total VC funding for biotech since 2008 ($1.16 billion) › Convenient, daily access to key federal agencies to facilitate the drug approval process › A strong bioscience community and support network through bioparks, tech councils, and incubators › The state of Maryland is 4th in research and development expenditures at colleges and universities ($3.41 billion) › Greater Baltimore/Central Maryland is home to over 260,000 BioHealth professionals › Baltimore-Washington is #1 in the US for percent of the population with bachelor’s or master’s degrees

Source: Blue Ridge Institute for Medical Research

#4 2012 NIH Awards to CitiesBRIMR

#4 R&D Tax CompetitivenessKPMG

Leading International Regions for R&DExpenditure as a Percentage of GDP

2012

Rank City Studied (State) %

1 Albuquerque (NM) 7.65%

2 Baltimore (MD) 5.90%

3 Boston (MA) 5.49%

4 Hartford (CT) 5.01%

5 Seattle, Spokane (WA) 4.99%

Source: Competitive Alternatives, KPMG

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University ofMaryland BioPark

bwtech@UMBCResearch & Technology Park

Science + TechnologyPark at Johns Hopkins

The distance between Baltimore and Washington, D.C. is approximately 35 miles.

Amtrak / MARC Rail Line

Light Rail Line

Baltimore Metro Subway

Research Facilities and Federal Institutions

Bioparks and Life Science Incubators

Philadelphia

1 E. Pratt Street, Suite 200, Baltimore, MD 21202 | 410.468.0100 | 888.298.4322 | www.greaterbaltimore.org

Largest Biotechnology CompaniesGreater Baltimore (2012)

Rank Company Employed

1 BD Diagnostics 1,600

2 Quest Diagnostics 1,200

3 Pharmaceuticals Intl. 450

4 Nutramax Laboratories 250

5 Science & Technology Corp. 240

6 GE Healthcare 218

7 Battelle 200

8 GEA Process Engineering 175

9 Martek Biosciences Corp. 172

10 Shimadzu Scientific Instruments 160

Source: Baltimore Business Journal