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Copyright ⓒ 2020 BR PHARM CO., Ltd. all rights reserved.
Bio-pharmaceutical company with expertise of regenerative medicine
BR PHARM is bio-pharmaceutical company
specialized studying and developing APIs, medicine,
medical devices and also cosmeceuticals.
Business Scop
Medicine Medical Device Cosmeceuticals Food
PDRN API
PDRN Inj.
PDRN/PN Healer
PN Intra-articular Inj.
HA Dermal Filler
Lipolysis Inj.
PDRN Cosmetics
Anti-pigment
Anti-trouble
<Research and development in
Progress>
Location
Research Institute
Marketing&Sales
Head office & Factory
API production facility
Seoul
Won-Ju
Go-Heung
Overview
History
Obtained KGMP for pharmaceutical injection
Listed PDRN raw material medicine on DMF(Drug Master File) & bGMP
Obtained China FDA total 31 kind of products (since 2017.03)
Started contruction of API production facility in Goheung-gun
Obtained CE for cross-linked hayluronic acid filler
Obtained Cosmetic GMP, ISO22716
Signed a MOU with Jollanam-do Goheung-gun
Completed construction of 1st factory in Wonju
Signed a MOU with Jollanam-do Oceans Fisheries Science Institute
Obtained GMP certification from MFDS
Obtained ISO13485(No. 820083) for HA and PDRN
Obtained license of pharmaceutical manufacturing
Changed company name to BR Pharm Co., Ltd.
Obtained license of medical device manufacturing
Established BR Beautiful Revolution Co., Ltd.
• 2020.03
• 2019.01
• 2018.04
• 2017.11
• 2017.11
• 2017.09
• 2016.12
• 2016.10
• 2016.07
• 2016.02
• 2015.12
• 2015.07
• 2015.06
• 2014.08
• 2005.07
PDRN
Identity
PDRN(PolyDeoxyRiboNucleotide)is DNA derived from a controlled purification
and sterilization process of the sperm of Oncorhynchus mykiss (Salmon Trout).
PDRN is a well-known stimulator of cell growth that that accelerates cell
proliferation and can help with the regeneration of skin and tissue. Due to
95% similarity between human DNA and PDRN,
It is proven to be safe and effective
95% identical
BR PHARM’s PDRN
Raw material (sea trout) seawater culture,
No-antibiotic, Eco-friendly Growth Environment
Self-developed high purity PDRN purification
technology(Patent pending)
Active Pharmaceutical Ingredients(API)
approved by KFDA(MFDS)
Raw materials with proven safety (Trout / salmon)
Raw materials grown in a safe environment from chemicals and harmful substances
PDRNPurification Technology
PDRN molecule size control technology according to the application
High Purity PDRN extraction technology(Remove unnecessary protein)
Certified production facility
Systematic quality control and safety test process
Manufacture production at certified production facilities
Safe raw materials
BR PHARM’s PDRN is..
BR PHARM’s PDRN
01 02 03Eco-Friendly Trout Farming
Trout Growth MeasurementDisease screening
PDRN PurificationQuality Test 04
Produce PDRN raw materials and finished products in GMP area
Thorough quality control and traceability from raw material state, and produce PDRN pharmaceutical ingredients with proprietay PDRN separation and purification technonology in bGMP certified facility
Sea trout farming
(History Tracking, ISO9001&HACCP
Certified )
BR PHARM's original
PDRN separation
extraction technology
and safety test
KFDA Certified PDRN
GMP certified production facility
BR PHARM’s PDRN
Study of PDRN’s wound healing effect
Annals of Dermatology Vol. 31, No. 4, 2019
Polydeoxyribonucleotide (PDRN) stimulates wound healing at diabetic mouse model.Digital camera images (D3200; Nikon, Tokyo, Japan). It was confirmed that the area of the wounds was reduced visuallywith time after skin damage. PBS: phosphate-buffered saline
Effects of polydeoxyribonucleotide (on cytotoxicity and proliferation in human dermal fibroblast neonatal (HDF-n) cells. (A) The cytotoxicity of PDRN was measured using CCK-8 reaction solution in on HDF-n cells. The percentage of viable cells was expressed as a proportion of control cell viability, which was set to 100%. (B) The cell proliferation of HDF-n cells at 48 and 72 hours. The number of HDF-n cells treated with PDRN.
SCIE (Science Citation Index Expanded)
BR PHARM’s PDRN
(2) Assessment of a PDRN injection in healing wounds (Chung-Ang Univ., Korea, 2014.09)
•
(1) Research about wound healing at State University of North Carolina. PDRN Research Paper
published on International Academic Journal leveled at SCI (2016.07)
( North Carolina A&T State University,
Effects of polydeoxyribonucleotide s (PDRN) on wound healing: Electric cell substrate impedance sensing (ECIS) )
(PDRN의 상처 치유 효과)
Study
Certification
Certifications
✓ Drug Master File for PDRN API ✓ KGMP (PDRN Injection)✓ bGMP for PDRN API
Certifications
✓ ISO 13485 ✓ GMP
Certificate of Free Sales
✓ CFS (issued by MFDS, Korea FDA)
Certifications
CE2292 (Medical Device Directive 93/42/EEC)Cross-linked Hyaluronic acid filler(Class III)
CE2265, Medical Device Class III, No. 2020-MDD/QS-068 PN Intra-artcular injection
Patent
• 2019.12 Manufacturing method of high purity DNA fragments mixtures (10-2053221)
• 2019.08 Manufacturing method of high purity DNA fragments mixtures (10-2019-0065676)
• 2014.10 A cosmetic composition having an anti-inflammatory and skin regenerative effect (10-1452313)
• 2013.10 Seborrheic alopecia agent and kit for photodynamic therapy comprising the tryptophan containing
(10-1318659)
• 2013.09 Acne and sebum secretion inhibitor, and the kit for photodynamic therapy comprising the tryptophan containing
(10-1308507)
Patents about skin regeration and skin trouble care
Global Network
Global Network
Shanghai Branch Office
동남아시아
Russia,
Ukraine,
Azerbaijan,
Georgia
Southeast Asia
(Singapore, Malaysia, Indonesia, Vietnam, Thailand)
Middle East
(Iraq, Iran, UAE, Kuwait)
Head Office & Factory
(Korea)
Participating Overseas exhibition
• Europe
▪ AMWC Monaco
▪ IMCAS World Congress
• SouthEast Asia
▪ Cosmobeaute Indonesia
▪ Cosmobeaute Malaysia
▪ Vietbeauty
• Middle Ease
▪ Arab Health (UAE)
▪ Dubai Derma (UAE)
• Russia
▪ InterCharm Moscow
• China
▪ CIBE(China International Beauty Expo) (Guangzhou)
▪ CBE(China Beauty Expo) (Shanghai)
▪ CMEF(China Medical Equipment Fair)
▪ Hong Kong Cosmoprof Asia
• Korea
▪ KIMES
Thank you