BIBLIOGRAPHY

Will i s , R . A . , (19671, I n :"Pathology of Tumours", 4 t h

Ed. p .1 , Appleton-Century-Crafts , N . Y .

De V i t a , V.T. J r . , and Busch, H . E . , ( 1 9 7 9 ) , eds .

1n:"Methods of Cancer Research", Vols. 1-18, Academic,

P re s s N.Y.

M i l l e r , E . C . , and M i l l e r , J . A . , ( 1 9 8 1 ) , Cancer.47: 1055.

Hoover, R . , and Fraumeni, J . F . , ( 1 9 8 1 ) , Cancer.47: 1071.

Boice, J . D . , and Hutchinson, G . B . J . , ( 1 9 8 0 ) , N ~ L ! .

Cancer Inst- . 65:115.

Merigan, T.C., ( 1 9 8 1 ) , Cancer.47: 1091.

American cancer S o c i e t y (1987) "Cancer F a c t s & Figures1'.

Rous, P . A . , ( 1 9 1 1 ) , J . Exp. Med. 13;397

Urbach, F . , ( 1 9 6 9 ) , Ed. The Bio log ic E f f e c t s of

U l t r a v i o l e t R a d i a t i o n , Oxford, Pergamon P re s s .

F i n d l l y , G.H., ( 1 9 7 8 ) , Lancet . 1: 759-760. . .

Magnus, K . , ( 1 9 7 7 ) , I n t . J . Cancer.20: 477-485.

F i t z p a t r i k , T.B., Sober , A . J . , ( 1 9 8 5 ) , N . Engl. J . Med.

313: 818-819.

Scotto, J., & Fears T.R.; (1987),Cancer Invest.5: 275-283.

Doniger, J ., Jacobson, E.D., (1981), Proc. Natl. Acad. Sci. (USA), 78: 2378-2382.

Sutherland, B.M., Delthas, N.C.,(1981), Cancer Res.41:

2211-2214.

Suthertand, B.M., (1980), Cancer Res. 40: 1934-1939.

Cleaver, J.F., (1983), Xeroderma Pigmentosum. In: Stanbury,

J.B., Wyngaarder, J.B., Fredrickson, D.S. et a1 (eds).

?he metabolic basis of Inherited Disease pp.1227-1.248

New York.Mc Graw Hi1 l .

Pott, P., (1775), London, Hawkes, Clarko & Colling,

Chirugical observation relative to the cataract, the

polypus of the nose, the Cancer of the Scrotum, the

different kinds of ruptures and the Mortification of the

Toes & Feet.

Rehn, L., (18951, Blasengeschwiilsste bei Fuchsin

Arbeitern Arch Klin Chir. 60:588.

Yamagiwa, K.,& 'Ichikawa,~;(1915), Mittelungen Med.

Facu1tat.Kaisen.Univ. Tokyo. 15: 295.

Kennaway, E.L., Hieger, I., (1930), Br. Med. J.1: 1044.

Pitot, H.C., Beer, D., Hendruch, S.(1987), Multistage

Carcinogenesis. in:Iverson O.H(ed) Theories of Carcinogenisis

P.159 Washington DC, Hemisphere Publishing.

Huberman, E., and Sachs, L.,(1977), Int. J. Cancer. 19:

122-127.

Essigmann, J.M., Groy, R.G., Nadzan, A.M., Busby,

W.F., Reinhold, V.N., Buchi G., and Wagan, G.N.,(1977),

Proc. Natl. Acad. Sci., USA, 74; 1870-1874.

Miller, E.C., and Miller, J.A.,(1976), In. Chemical

Carcinogens.C.E., Searle, (Ed) ACS, Washington.P.732.

Slaga, T.J., Scribner, J.D., Thompson, S., and Viaje,

A. J.,(1974), Natl. Cancer Inst. 52: 1611-1618.

O'Brien, T.G. , Simsiman, R.C., and Boutwell, R.K.,

(1975), Cancer Res. 35:1662 -1670.

Slaga, T . J . , Bowden, G.T., and Boutwell, R.K., (1975),

Natl. Cancer Inst. 55: 983-987.

S1 aga, T . J . , Sivak, A., and Boutwel l , R.K., (eds)

(1978), Carcinogenesis : A comprehensive Survey Vol. 2,

Mechanisms of Tumour Promotion and Carcinogenesis,

Raven Press, N.Y.

Pitot, H.C., (19861, Fundamentals of Oncology, 3rd (ed),

New York.

Nishizuka, Y., (1986), Sciegce. 233: 305.

Housey, G.M., Johnson, M.D., Hasiao, W.L., O'Brian, C.A., b.

Murphy, J.P., Kirschmeier, P., and Weinstein, I.B., (1988),

Ce11.52: 343.

Yuspa, S.H., Hennings, H, Sako, T,, Pettit, G.R.,

Hartley, J.,and Blumberg, P.M.,(1987), In :Anticarcino-

genesis and Radiation Protection.Cerruti, P.A., Nygaard

O.F., and Simec, M.G., (eds) Plenum Press, New York.P.169

Ziboh, V.A., (1985), In: Arachidonic Acid Metabolism and

Tumour Promotion, Fischer, S.M., and Slaga, T.J., (eds)

Martinus, Nijhoff publishers; The Hague.P.6.

Copeland, E.S., (19831, Cancer Res. 43: 5631.

Cerruti, P.A., (19851, Science.227: 375.

Updayke, L.W., Chuthaputti.,A, Pfeifer, R.W., and Yim,

G.K.W (1988), Carcinogenesis.9: 11.

Verma, A.K., Shapas, B.G., Rice, H.M., and Boutwell,

R.K.,(1979),Cancer Res. 39:419.

Pitot, H.C., (1982),Cancer.49:1206.

Baltimore, D., (1974), Tumour Viruses, Cold Spring

Harbour Sym.0.D. Quantitave Biology.39: 1187.

41. Huebner, R.J., Todaro, G.J., (1969), Proc. Natl.Sci.(USA).

64: 1087.

42. Solomon, S., Garcia, R.R., Row1 and, F.S., (1986 ), Nature.

321: 755-758.

43. Sukumar, S., Notario, V., Martin - Zanea, D., and

Barbacid, M,, (1983), Nature, 306: 658.

44. Balmain, A.,and Pragnall, I.B.,11983), Nature. 303: 72.

45. Boone, C.W., Kelloff, G.J., and Malone, W.E., (1990),

Cancer Res. 50: 2.

46. Howie, A.F., Forrester, L.M., Glancey, M.J., Schlager,

J.J., Powis, G., Beckett, G.J., Hayes, J.D., and Wolf, ,

C.R., (1990), Carcinogenesis. 11: 451.

47. Willett, W.C., and Stampfer, M.J., (1986), J.Am.

Col .Toxicol . 5: 29-36.

48. Ip,C. (1986), J.Am. Col. Toxicol. 5: 7-20.

49. Schwartz, A.G., and Tannen, R.H., (1981), Carcinogenesis

(Lond). 2: 1335-1337.

50. Weeks, C.E., Hermann, A.L., Nelson, F.R., and S l a g a ,

T.J., (1982),Proc. Natl. Acad. Sci. USA. 79: 6028-6032.

51. Pollard, M, Lukert, P.H., Schmidt, M.A., (1983), cancer Let

21: 57-61.

Schuman, L.M. , Mandell, J . S . , Radke, A . , S e a l , U . , and

Halberg,F. , ( 1 9 8 2 ) , I n : Magnus, K . , ( e d ) Trends i n Cancer

inc idence . Causes and P r a c t i c a l Imp l i ca t i ons . pp. 345-

353 Washington, D C . , Hemisphere Publ i sh ing Corp.

Sheke l l e , R . B . , L iu , S . , Rynor, W.J., J r . Lepper, M . ,

Maliza, C . , and Rossa f , A . H . , (1981) ,Lance t . 2: 1185-1190.

S t a h e l i n , H . B . , Rose l , F . , Buesse, E . , Brubacher, G . ,

( 1 9 8 4 ) , J . Na t l . Cancer I n s t . 73: 1463-1468.

Graham, S . , Haughey, B . , Marsha l l , J . , P r i o r e , K . ,

Byers, T . , Rzepka, T . , Met l in , C . , and Pontes , J . E . ,

( 1 9 8 3 ) , J . Na t l . Cancer I n s t . 70:687-692.

Heshmat, M . Y . , Kaul , L . , Kovi, J . , Jackson, A . M . , Jackson,

A . G . , J ones , G . W . , Edson, M . , E n t e r l a n e , J . P . , Worrel , R . G . &

P e r r y , S.L. , (1985), The P r o s t a t e . 6 : 7-17.

Moon, R . C . , MC Cormick, D . L . , and Mehta, R . G . , ( 1 9 8 3 ) ,

Cancer Res. 43: 2469.

Weisberger, J . H . , Marquardt . , H . , Mower, H.F., H i r o t a ,

N . , Mori. , H..and Wil l iams, G . , ( 1980) ,P rev . Med. 9:352-361.

P ipk in , G.E. ,(1969),Proc.Soc. Exp. B io l . Med. 131: 522-524.

Wassertheir-Smol l e r , S . , Romney, S 1 , Wyl i e -Rose t t , J . , S l a g l e , S . , M i l l e r , G . , Lucido, D . , Dut tagupta , C . ,

and Pa l an , P . R . , (1981),Am. J . Epidemiol. 114: 714-724.

Decosse, J.J., Adams, M.B., Kuzma, J . F . , and Codon,

R.E., (1975),Surgery. 78: 608-612.

Bussey, J . H . , Decosse, J.J..and Deschmer, E.E., (19821,

Cancer (Phila). 50 : 1434-1439.

MC Keown-Eyssen, G., Holloway, C., Jasmaji, V., Bright-

See, E., Dion, P.,and Bruce, W.R., (1988),Cancer Res.48:

4701-4705.

Block, G., and Menkes, M.,(1988),Moon, T., and Micozzi, \

M.,(eds) In: Nutrition and Cancer Prevention. The role

of Micronutrients New York. Marcel. Dekker.

Newberne, P'.M., and Suphakaran, V., (1983),Nutr. Cancer.

5: 107-119.

Nomura, A.M.Y., Stemmermann, G.N., Heilbrun, L.K.,

Salkeld, R.M., and Vuillemumier, J.P., (19851, Cancer

Res. 45: 2369-2372,

Gey. K.F., Brubacher, G.B., and Stahelin, A.B., (198-),

Am. J., Clin. Nutr. 45: 1368-1377.

Bird, R.P., Schneider, R., Stamp, D., and Bruce, W.R.,

(19861, Carcinogensis (Lond). 7: 1657-1661.

Pence, B.C., and Buddingh, F . , (1957),Proc. Am. Assoc.

Cancer Res. 28: 154.

B u t t e r w o r t h , C.E. , Ha tch , K . D . , Gore , H., M u e l l e r , H.,

and Krumdieck, C . L . , (1982),Am. J . C l i n . N u t r . 35: 73-82.

S h a k l a r , G . , ( 1 9 6 6 ) , Cancer Res .26: 2218-2224.

E l s o n , C.E. , Maltzman, J . I . , Bos ton , J . I . , and T a b b e r ,

M . A . , ( 1 9 8 8 ) , C a r c i n o g e n e s i s (Lond l .9 : 331-332.

Wat tenberg , L.W., Hanley , A . B . , Barany , G . , S p a r n i n s ,

V.L., Lam, L . K.T., and Fendwick, G . R . , ( 1 9 8 5 ) , D i e t

N u t r i t i o n and Cancer. PP. 193-203.

Watteriberg, L.W., ( 1 9 8 5 ) , C a n c e r Res. 45: 1 -8 .

Wel, H . , Tye , L . , B r e s n i c k , E . , and B r i t , D.F., ( 1 9 9 0 ) ,

Cancer Res. 40: 499-502.

Wat t enbe rg , L.W., ( 1 9 9 2 ) , Cancer Res. 52 : 2085-2092.

T r o l l , W . , Wiesne r , R . , and F r a n k e l , K . , ( 1 9 8 7 ) , Cancer

Res. 49 : 265-283.

Rubio , C . A . , ( 1 9 8 4 ) , J . N a t l . Cancer I n s t . 72: 705-707.

K e l l o f f , G . J . , Malone, W.F., Boone, C . W . , Sigman, C . C . ,

and Fay , J . R . , ( 19901 , Semin. Oncol . 1 7 : 438-455.

Committee on D i e t , N u t r i t i o n and Cance r , ( 1 9 8 2 ) , PP.358-

370 Washington D . C . Na t iona l Acadamy P r e s s .

Padma, P.R., Lalitha, V.S., Amonkar, A.J., and Bhide,

S.V., (19891, Cancer Lett. 45: 195.

Nagabhushan, M., and Bhide, S.V., (19871, J. Nutr. Crowth.

Cancer. 4: 82.

Hussain, S.P., and Rao, A.R., (1991),Cancerr Lett. 56: 231.

Salomi,, M.J., Nair, S.C., and Panikkar, .K.R., (1991),

Nutr. Cancer. 16: 67-72.

Nair, S.C., Panikkar, B., Akamanchi, K.G., and Panikkar,

K.R., (1991),Cancer Lett. 60: 253.

Katiyar, S.K., Agarwal, R., Wang, Z.Y., Bhatia, A.K.,

and Mukthar, H., (1992), Nutr. Cancer. 18: 73.

Sugar Baker, E.V., (1981), Cance~Res. 41: 235.

Brule, G., Eckhardt., S.J., and Hall, T.C., (eds) (1973),

In: "Drug Therapy of Cancer", WHO, Geneva.

Tomio, L., Calzavara, I., Zorat, P.L., and Corts, L.,

(1984) , In: "Porphyrun local ization and treatment of

Tumours" Doiron, D., and Gomer, C.J., (eds) Alan R.

Liss, NY P.829.

Gilson, D., Ash, D., Driver, I., Feather, J.W., and

Brown, S. (1988),Br. J. Cancer.58: 665.

Hisazumi, H., Mizaki, T., and Miyozhi, N., (1983), J Urol.

130: 685.

Tripodi, D., Parks, L.C., and Brugmans, J., (19731, N.

Engl . J . Med. 289: 354. Terry, W.D., and Rosenberg, S.A., (1982), In: Immuno

therapy of Human Cancer, Elsevier - North Holland.

Rosenberg, S.A., Lotze, M.T., and Mule, J.J., (19881,Ann.

Intern. Med. 108: 853.

Morgan, D.A., Ruscett, F.W., -and Gallo, R.G., (1976),

Science.193: 1007.

Mule,J.J., Shu, S., Schwarz, S.L., and Rosenberg, S.A.,

(1984) , Science. 225: 1487.

Rosenberg, S.A., Mule, J.J., Spiess, P.J., Reichert,

C.M., and Schwarz, S.L., (1985), J. Exp. Me. 161: 1169.

Spiess, P.J., Yang, J.C., and Rosenberg, S.A., (19871, J.

Natl. Cancer. Inst. 79: 1067.

Cameron, R.B., Spiess, P.J., and Rosenberg, S.A., (1990),

J. Exp. Med. 171: 249.

Murad, F., and Giln~on, A.G., (19751, In: Goodman, L.S., and

Gil man, A.,( eds) . The pharmacol ogical basis of Therapeutics

5th.ed. New York. The Macmillan Publishing Co. P.1451.

101. N o l l e r , K.L., and F i s h , C . R . , ( 1 9 7 4 ) , Med. C l i n . North

Am. 58: 793.

102. Melby, J . C . , (19771, Ann. Rev. Pharmacol. Toxicol . 17:511.

103. Devi ta , V.T., (1978) N . Engl. J . Med. 298: 907-910.

104. Dev i t a , V.T., Henney, J . E . , Hubbard, S.M., ( 1981) ,

Es t imat ion of t h e numerical and economic impact of

Chemotherapy i n t h e t r ea tmen t of cancer . I n : Bruchenal ,

J . H . , Oc t tgen , H.S., ( e d s ) , Cancer Achievements,

Chal lenges and P rospec t s f o r t h e 1980s pp. 857-880. New

York Grune & S t r e t t o n .

105. S l e e t , G . G . , ( 1 9 6 8 ) , Cel l t i s s u e K i n e t i c s .l: 193-207.

106. Goodman, L.S., ( 1 9 4 6 ) , J . Amer. Med. Assoc. 132: 126.

107. Farber , S . , Diamond, L .K . , Mercer, R . D . , S y l v e s t e r , R.F. ,

and Wolff, J . A . , ( 1948) , N . Eng1.J. Med. 238: 787.

108. Chabner, B . , Myers, C . E . , and O l i v e r i o , V . T . , ( 1 9 7 7 ) ,

Oncol. 4: 165.

109. Wheeler, G . P . , ( 1 9 7 3 ) , A lky la t i ng a g e n t s , I n : Holland,

J . F . , and F r e i , E . , 111 ( E d s ) : Cancer Medicine,

P h i l a d e l p h i a , Lea and F e b i g e r , P.791.

110. Ludlum, D.B., (1977), In: Becker, F.F., (ed). Cancer a

Comprehensive treatise. Vol.5: pp. 285-307. New York

PI enum Press.

111. Arnold, H., and Bourseaux, F., (1958),Angew Chem. 70: 539.

112. Sauham, R.L., Harper, P.G., Linch, D., Traske,

Fioldstone, A.H., and Richards, J.D., (1982), Cancer

Chemother. Pharmacol. 8: 31-34.

113. Struck,R.F.,Kurk, M.C., Mellett, L.B., El Dareer, S.,

and Hi1 l, D.L., (1971), Mol . Pharmacol .7: 519-529. 114. Takamizawa, A . , Tochino, Y., Hamashima, Y., and Iwata,

T. (1972),.Chem. Pharm. Bull. 20: 1612-1616.

115. Struck, R.F., (1974), Cancer Res. 34: 2933-2935.

116. Struck, R.F., Kirk, M.C., Witt, M.H., and Laster, W.R.,

Jr. (19751, Biomed. Mass spectrum. 2: 46-52.

117. Bakke, J.A., Feil, U.J., Fjelstul, C.E., and Thacker

E.J., (1972), Food. Chem. 20: 384-388.

118. Connors, T.A., Cox, P.J., Farmer, P.B., Foster, A.B.,

and Jarman, M., (19741, Biochem. Pharmacol. 23: 115-129.

119. Colvin, M,, Brundertt, R.B., Kan, M.N., Jardine, I., and

Fenselan, C., (1976) Cancer Res. 36: 1121-1126.

120. Zief, M.,and Schramm, C.H.,(1964), Chem. Ind. 16: 660.

Shaw, J . C . , Graham, M . I . , and Mclean, A.E.M., ( 1 9 8 3 ) ,

Cancer T rea t Rev. 10. ( S u p p l e . ) : 17 .

Dahl Mac, Gregory, M . M . , Scheur P . J . , ( 1 9 7 1 ) , B r . Med.

3.1: 625-630.

Bleyer , W . A . , (19781, Cancer.41: 36-51.

Cohen, S.S. , ( 1 9 7 6 ) , Med. B i o l . 54: 299-326.

Tidd, D.M. , and Pa t e r son , A . R . P . , (1974),Cancer Res. 34:

733-737.

C h r i s t l e , N.T., Drake, S . , Meyn, R . E . , (19841,Cancer Res.

44: 3665-3672.

Schwartz, H.S., (1975) Res. Commun, Chem. Pa tho l .

Pharmacol. 10: 51.

Ross, W.E., Zwel l i n g , L.A., and Kohn, K.W., (1979) , I n t . J . Radia t . Oncol. Biol .Phys . 5 : 1221.

Blum, R . H . , and C a r t e r , S.K., (19741, Ann: 1ntern.Med.

80: 249.

Rosenberg, B . , Van Camp, L . , and Khigas , T . , (19651,

Nature. 205: 698-699.

Rober t s , J.J., and Thornson,A.J., ( 1 9 7 9 ) , Prog. Nucle ic

Acid Res. Mol . Biol . 22: 71-133.

Fravel, H.N., Rawlings,C.J.,and Roberts,J.J., (1978),

Mutat. Res. 51: 121-132.

Meyn, R.E., Jenkins,S.F., and Thompson,L.H.,(1982),

Cancer Res. 42: 3106-3110.

Eastman, A., (19871, Pharmacol Ther. 34: 155-166.

Anonymous (19821, Lancet.1: 374-375.

Rozenewig, M., Von Hoff, D.D., and Slavik,M., (1977),

Ann.Intern. Med. 86: 803.

Allan, S.G., Smyth, J.F., Hay, F.G., Robert, C.F.,and

Wolf, C.R., (19861,Cancer Res. 46: 3569-3573.

Spivack, S.D., (19741, Ann. Intern. Med. 81: 795.

Weinkam, R.J., and Shibu, D.A., (19781,Life Sci.

22: 937-945.

Krets, W., and Yen, Y., (1965),Experentia. 21: 284-285.

Wasserman, T.H., (19751, Cancer Chemother. Rep. (part 3)

6: 399.

Seiber, S.M., and Adamson, R.H., (1975),Adv. Cancer Res.

22: 57.

Lewis, W.H., and Wright, J.A., (19.741, Bioche~ri.

Biophys. Res. Commun. 60: 926.

- 161 - 144. Schwartz, J.H., and Canellos, G.P.,(1975),Blood, 46: 11.

145. Lerner, H.I. Malloy, T., and Cromic, W.,(1975), J. Urol.

114: 425.

146. Stef ani, S., Eel S, R.W., and Abbate J. ,( ig7&),~adiology. 1~.~1:391.

147. Calabresi, P., and Parks, R.E., Jr. (1975), The

Pharmacological Basis of Therapeutics 5th Ed. New York,

The Macmillan Company P.254.

148. Kidd, J.G., (19531, J. Exp. Med.. 98: 583.

149. Broome, J.D., (1961), Nature.191: 1114.

150. Haskell, C.M., and Canellos, C.P., (1969),Biochem.

Pharmacol . 18: 2578. 151. Sfrei 111, E. (1982), Science.217: 600.

152. Hartwell, J.L., (1971), Lloydia, 34: 386.

153. Hartwell, J.L., (19761, Cancer Treat. Rep.60: 1931.

154. Cassady, J.M., Chang, C.J., and McLaughlin, J.L.,

(1981) ,In: Natural Products as Medicinal Agents "Beal , J.L. and Reinhard, E. eds., Hippokratis-Verlaj,

Stuttgart, p.93

155. Suffness, M (1985),"Advances in Medicinal Plant

Research", Vlietinek, A.J. and Dommisse, R.A., eds.,

Wissenschaftliche Verlagsgesel1schaft, Stuttgart, p.lO1.

Suffness, M., and Douros, J., (1979),In: "Methods in

Cancer Research", Devita, Jr., V.T.,and Buch, H.,eds.,

Academic Press, New York, San Francisco, London, 16A, P.73.

Umizawa, H.,(1979),In: "Methods in Cancer Research",

Devita, Jr., V.T.,and Busch, H. eds., Academic Press,

New York, San Francisco, London, 16A, P.43.

Suffness, M.,and Douros, J.J.,(1982),Nat. Prod. 45: 1.

Cassady, J.M., and Douros, J.D., (19821, Eds. In:

"Anticancer Agents Based on Natural Product Models",

Academic Press, New York, 1980.

Haskell, C.M.,(1985),In: "Cancer Treatment", 2nd edn.,

Haskell, C.M., ed., W.B. Saunders. p.43.

Lomax, N.R., and Narayanan, V.L.,(1986),In: "Chemical

Structurues of Intrest to the Division of Cancer

Treatment", 5: 1.

Cragg, G.M., and Suffness, M.,(1986), 27th Annual Meeting

of the American Society of Pharmacognosy, Ann.Arbor, MI.

Alley, M.C., Scudiero, D.A., Monks, A., Hursey, M.L.,

Czerwinski, M.J., Fine, D.L., Abbott, B.J., Mayo, J.G.,

Shoemaker, R.H., and Boyd, M.R.,(1988),Cancer Res.48: 589.

164. Noble, R.L., Beer, C.T., and Cults, J.H., (1958),

Biochem. Pharmacol. 1: 347,

165. Bensch, K.G., and Malawista, S.E.,(1969),J. Cell Biol.40: 95.

166. Livingston,.R.B., and Carter, S.K., (1970),Single Agents

in Cancer Chemotherapy, New York, Plenum Publishing Corp.

167. Wasserman, T.H., et a1 (1975), Cancer Chemother. Rep.

(Part 3) 6: 399.

168. Rosenthal, S., Kaufman, S., (1974),Ann. Intern. Med. 80: 733.

169. Yamamoto, I., Takshashi, M., Tamura, E., Maruyama, H.

(1982), Botanica Marina. 25: 455.

170. Fujihara, M., Jizima, N.,Yamamoto, I., Nagumo, T.,

(1984), Carbohyd. Res. 125: 97.

171. Okamoto, K., Tomita, Y., Yonezawa, H., Hirohata, T.,

Ogura, R., Izumiya, N., (1984), Oncology. 41: 43.

172. Suga, T., Shiio, T., Maeda, Y.Y., Chihara, G.,(1984),

Cancer Res. 44: 5132.

173. Sezzi, M.L., Zupi, G., De Luca, C., Materazzi, M.,

Bellelli, L., (1984), Anticancer Res. 4: 239.

174. Sezzi, M.L., De Luca, G., Materazzi, M., Bellelli, L.,

(19851, Anticancer Res. 5: 265.

Bellelli, A., Camboni, C., De Luca, G., Materazzi, M.,

Mattioni, M., Sezzi, M.L., Bellelli, L., (19871,

Oncol ogy . 44 : 17 Furusawa, E., Furusawa, S., (1985), Oncology. 42: 364.

Beljanski, M . , Beljanski, M.S., (1986),0ncology. 43: 198.

Fimiani, V., (1987), Oncology. 44: 42.

Salomi, M.J., Nair, S.C., Jayawardhanan, K.K., Varghese,

C.D., and Panikkar, K.R., (19921, Cancer Lett. 63: 41-46.

Nair. S.C., Salomi, M.J., Varghese, C.D., Panikkar B.,

and Panikkar, K.R., (1992), Biofactors, 4: 69.

Nair, S.C., and Panikkar, K.R., (1990),Cancer Lett. 49:

121-126.

De Wilde, (1967), Blumea.15.2: 394.

Srivastava, G.N., Bagchi, G.D., and Srivastava, A.K.,

(19881, Int. J.Crude Drug. Res. 26.2: 65-72.

Ghosh, B.,(1987), Indian J. For. 10.3: 173-183

Ayurveda Pharmacopia., (1976),Dept. of Ayurveda, Colombo,

Sri Lanka. I.P. 250.

Dey, K.L., Rai Bahadur.,(l973), The Indigenous Drugs of

1ndia.Publisher Pama Primlane, The Chronica Botanica,

New Del hi. p. 286-87.

Patel, B.R., and Satakopar~, S.,(1979), Indian Drugs,

17.3: 67-69.

Kapoor, S.L., and Mitra, R.,(1979),Herbal Drugs in

Indian Pharmaceutical Industry, Economic Botany

information Service, NBRI, Lucknow.

Middlekoop, T.B., and Labadie, R.P., (1983), J. Ethano-

pharmacol. 8: 313-320.

Edwards et al. (1952),Indian For. Rec., N-S, Chem. and

Minor For. Prod. 1.2: 154.

Achari, and Lal, (1952), Indian Pharm. 7: 244.

Mukherji et al; (1970), Indian J.Pharm. 32: 48.

Satyavati, G.V, Prasad, D.N., Sen, S.P., and Das, P.K.

(19701, Ind. J. Med. Res. 58:947-960.

Satyavati, G.V., (1969),Ind. J. Med. Res. 57: 37.

Kirt, and Basu, (19201, FI. Assam.2: 137.

'Middelkoop, T.B., Labadie, K.P., (1985),Z.Natur. Forsch.

40.C.7,8: 523-26.

198. Prasad et al; (1961),J. Sci Industr. Res. 20C: 125.

199. Nambiar, V.P.K., (19831,Our Vanishing Medicinal Trees,

Saraca asoca (Roxb.) de. Wilde. Evergreen, 10,12, For.

Abstr.45 (1) 26: 208.

200. The Wealth of India., (1972),A dictionary of Indian Raw

Materials and industrial products, CSIR. 9: p.232.

201. Indrani, N., and Balasubramanian., (1984),K.Leather Sci.

30: 11.

202. Behari, M., Andhiwal, C.K., and Ballantinal, J.A., (1977),

Indian J. Chem, 15 B: 765.

203 Sen, S.P., (1963), Curr. Sci. 32: 502.

204. Kaur Duggal, J,, and Misra, K., (1980),J. Indian Chem.

Soc. 57.

205. Thompson, R.S., Jacques, D., Haslam, E., and Tanner

R.J.N., (1982),J.Chem. Soc. Perkin I, 1387.

206. Indrani, N., and Balasubramanian, K., (1985),Leather

Sci. 32(1): 12-14.

207. Indrani, N., and Balasubramanian, K. (1984),Leather

Sci. 31 (12): 349-51.

208. Frei, E., (19721, Cancer Res. 32: 2593.

209. Perloff, M., and Holland, J.F., (1977),Ann. Rev. Med.

28: 475.

210. Devita, V.T., Sirnon, R.M., Hubbard, S.M. (1980),Ann.

Intern. Med. 92: 587-595.

211. Gringeri, A., Kong, P.C., and Borch, R.F., (1988),Cancer

Res. 48: 5708.

212. Ozols, R.F., Corden, B.J., Jacob, J., Wesley, M.N.,

Ostchega, Y., and Young, R.C., (1984) Ann. Intern. Med.

100: 19-24.

213. Gandara, D.R., Mansour, R., Wold, H.,and George, C.,

(1986),Cancer Treat. Rep. 70: 820-821.

214. Patel, A.R., Shah, P.C., Rhee, H.L.,(1976),Cancer. 38:1542.

215. Wall, R.L., and Clausen, K.P., (1975),N.Engl. J. Med.

293: 271.

216. Bennett, W.M., Singer, I., Golper, T., (1977), Ann.

Intern. Med. 86: 754.

217. Toplow, A.A., Kothenberg, S.P.,and Cottrell, T.S.,(1973),

Ann. Rev. Respir. Dis. 108:114.

218. Carter, S.K., and Livingston, R.B., (1975),Cancer Treat.

Rev. 2: 295.

219. Slater, S.K., Canetta, R., and Rosenweig, M., (1985),

Cancer Treat. Rep. 12 (Supp1.A) : 145-152.

220. Slater, T.F., Ahmed, M., and Ibrahim, S.A., (19771,

J .Cl in. Hematol . Oncol . 7 : 534-546.

221. Yuhas, J.M., and Culo, F., (1980),Cancer Treat. Rep.

64: 5764.

222. Borch, R.F., and Pleasants, M.E., (1979),Proc. Natl.

Acad. Sci. USA, 76: 6611-6614.

223. Borch, R.F., Katz, J.C., Lieder, P.H., and Pleasancs,

M.E., (1980). Proc. Natl. Acad. Sci. USA.77: 5441-5444.

224. Gringeri, A., and Borch, R.F.,(1984),Proc. Assoc. Cancer

Res. 25: 371.

225. Dible, S.E., Siddik, Z.H., Boxall, F.E., and Harrap,

K.R.,(1987), Eur. J . Cancer. Clin. Onco1.23: 813-818.

226. Dedon, P.C., and Borch, R.F., (1987), Biochem. Pharmacol.

36: 1995.

227. Bodenner, D.L., Dedon, P.C., Keng, P.C., Katz, J.C., and

Borch, R.F., (1986). Cancer Res.46: 2751-2755.

228. Bhanumathy, P., Kurar, S., Vasudevan, D.M.,(1986),Ind

J . Exp. Biol. 24: 767.

229. Kumar, S., Raghunath, P.N., Joseph, C.D., Vasudeviln,

D.M.,(19851, Ind. J.Cancer. 22: 228.

230. Indap, M.A., and Gokhale, S.V., (1986),Ind. J. Physiol.

Pharmacol . 30: 182.

231. Nair, S.C., Salomi, M.J., Beena Panikkar , and Panikkar,

K.R., (1991), J. Ethanopharmacol . 31: 75-83. 232. Nair, S.C., Salomi, M.J., and Panikkar, K.R., (1990),

proc. Natl. Semi. Cancer.1: 28-30.

233. Hahn, G.M., (1979), Cancer Res. 39: 2264.

234. Lehman, J.F., (1982),Therapeutic Heat and Cold, ed. 3

Baltimore: Will Lams and Wil kins.

235. Dewey, W.C., Hopwood, L.E., Sapareto, S.A., Gerweek,

L.F. (1977),Radiology.123: 463-474.

236. Westra, A . , Dewey, W., (1971),Int. J. Radiat. Biol. 19:

467-477.

237. Cress, A.E., Cuver, P.S., Gerner, E.W., (1982),Cancer Res

42: 1716-1721.

238. Lepock, J.R., (1982),Radiat. Res. 92: 433-438.

239. Roti Roti, J.L., Winward, R.T., (1978),Radiat. Res. 74:

159-169.

240. Wheeler, K.T., Warters (1982),Radiat.Res. 90: 204-215.

241. Roti Roti, J.L., Painter, R.B.,(1982),Radiat Res.89: 166-175

242. Warters, R.L., Roti Roti, J.L., (1981),Radiat. Res. 92:

458-462.

243. Li, G.C, Peterson, N.S., Mitchel, H.K.,(1982), Int. J.

Radiat. Oncol. Biol. Phys. 8: 63-67.

244. Roti Roti, J.L., Henle, K.J., Win ward, R.T., (1980),

Radiat. Res. 84: 504-513.

245. Wong, R.S.L., Dewey, W.C., (1.982),Radiat.Res. 92: 370-395.

246. Warters, R.L., Stone, O.L.,(;983),Radiat Res. 93.8: 71-84. <

247. Hahn, G.M., and Strande, D.P.,(1976),J.Natl. Cancer Inst.

37: 1063.

248. Meyn, R.E., Corry, P.M., Fletcher, S.E., and

Demetriades, M.(1979), Int. J. Radiat. Oncol. Biol. Phy.

5:1487.

249. Adwanker, M.K., Khandalekar, D.D., and Chitinis, M.P.,

(1984), Oncol ogy. 41: 370-373.

250. Fram, R., Skarin, A . , Balikian, J . , Amato, D., Leslie,

N., Malcolm, A . , and Fric I11 E. (1985), Cancer Treat.

Rep. 69: 587-590.

251. Carter, S.K., (1974),Cancer Chemother.Rep.4(1) 2: 3-12.

252. Pradhan, S.G., Basrur, V.S., Chitnis, M.P., and Advani,

S. H., ( 1984), Oncol ogy. 406-408.

253. Kessel, D., and Wilberding, C.,(1985),Cancer Treat. Rep.

69: 677-682.

254. Stewart, J.R., Jr. : Bagshaw, M.A., Corry, P.M., Gernrr,

E.W., Gibbs, F.A., Hahn, G.M., Lele, P.P. and Oleson,

J.R., (19841,Cancer Treat.Symp. 1: 135-146.

255. Roti Roti, J.L., (1982), Natl. Cancer Inst. ~ollogr,

256. Hahn, G.M., Brazen, J.C., and Har-kedar,I., (1975),Proc.

Natl. Acad. Sci.USA.72: 937-940.

257. Adwankar, M.K., and Chitnis.,(l984),Tumorim70: 231-234.

258. Murthy, M.S., Rao, L.N., Khandkar, J.D., and Scanlon,

E.F., (1987),Cancer Res.47: 774-779.

259. Urano, M., Kill], M.S., Khan, J., Kenton, L.A. and Li,

M.L., (1985), Cancer Res. 45: 4162-4166.

260. Twentyman, P.R., Morgan, J.E., Donaldson, J.,(1978),

Cancer Treat Rep. 62: 439-443.

261. Hahn, G.M., (1979), Cancer Res. 39: 2264-2268.

262. Bates, D.A., and Mackillop, W.J., (1986),Cancer Res. 46:

5477-5481.

263. Nisteswar, K., (1988),J. Nat. Integ. Med. Ass. 30(5): 9-10.

264. Paul, J., (ed) (1976),In: "Cell and tissue culture (5th

edn)" Church Hill Living Stone.P.232 and p.319.

265. Dunhan, L.J., and Stewart, H.L., (19531,J.Nat. Cancer

Inst. 13: 1299.

266. Foley, G.E., and Drolet, B.P.,(1956), Proc. Soc. Exp.

Biol . Med. 92: 347. 267. Dawe, C.J., and Potter, M (1957), Am. J. Path.33: 603.

268. Yasumura, T., and Kawakata, Y., (1963), Nippon Rinsho.

21: 1201.

269. Eagle,(1954), Proc. Soc. Exp. Biol. Med. 89: 362.

270. Lozzio, C.B., and Lozzio, B.B., (1975),BIood, 45: 321.

271. Freshney, R. I., (1987), In: "Culture of animal cell s , a

manuel of basic technique (2nd edn)". Liss, A.R., (ed)

Inc. N.Y. P.127.

272. Kaltenbach, J.P., Kaltenbach, M.H., and Lyons, W.B.,

(1958))Exp. Cell Res. 15: 112.

273. Talwar, G.P.,(ed) (1983), In: A hand book of Practical

immunology. Publishing House.Pvt. Ltd. New Delhi. P.275,

P.302, P.335.

274. Pavlik, E.J., Konda, D.E., Vanmagell, J.R., Keaton, K.,

Hansen, M.B., and Donaldson, E.S., (1983), Cancer

Chemother. Pharmacol. 11: 8.

275. Belijanski, M. and Belijanski, M.S., (1986),0ncology,

43: 198.

276. Bergmeyer, H.U., Bernt, E.,(1974),In: "Methods of

enzymatic analysis Vol. 2" Bergmeyer, H.U. (ed) , Academic Press, N.Y.P. 735.

277. King, E.J., and Armstrong, A.R., (1934),Canad. Med. Ass.

J. 31: 376.

278. Varley, H., Gowenlock, A.H., and Bell, M., (eds) (1980),

In: "Practical clinical Biochemistry" Wil l iam Heinemann

Med. books Ltd., L0ndon.P. 459.

279. Ellman, G.L., (1959), Arch. Biochem. Biophys. 82: 70.

280. Frei, E., Bertram, B., and Wiesller, M.,(1985),Chem.

Biol. Interact. 55: 123.

281. Goldberg, D., and Spooner, R.J., (1983),In:Methods of

Enzymatic Ana1ysis.p.p. 258-260.

282. Habig, W.Ii., Pabst., M.J., and Jakoby,W.B.,(1974),J.

Bi~l . Chem. 249: 7130. 283. Lowery, O.H., Rosebrough, N.J., Farr, A.L;,and Randal

R.J.,(19511, J. Biol. Chem. 193: 265.

284. Lutz, W.,(1978), In: "Handbook of experimental

immunology (3rd edn. ) " Weir, D.M., (ed 1, B1 ackwell

Scientific Publ. London, P.A.2:l.

285 Nadkarni,K.M.,(19761,In: K.M. Nadkarni's Indian Materia,

Medica,Popular prakashan, Bombay. 1:1104-1105

286. Neuss, N., Johnson, I.S., Armstrong, J.G., and Jansen,

C.L.,(19641,,. The Vinca Alkaloids, Advances Chemother.1: 133.

287. Belkin, M., (19481, J. Pharmacol.Exp. Ther. 93: 18.

288. Desombre, E.R., and Arbogast, L.C., (19741,

Cancer Res. 34: 1971.

289. Panikkar, K.R., Bhanumathy, P.,and Raghunath, P.N.

(1986), Ancient Sci.6: 109.

290. Weinberg, R.A., (1.991), Science. 254: 1138.

291. Di Giovanni, J., (19911, Prog. Exp. Tumour Res. 33: 192

292. Wattenberg, L. W., (1990), In: Antimutagenesis and Anticar-

cinogenesis. pp:155-156 Editors :Y. Kuroda, D.M., Shanke,

and waters, M.D PI enum Pub1 . , New York.

293. Birt, D.F., and Bresnick,'E.,(1990), In: Human Nutrition:

A comprehensive Treatise. 6: 111. Plenum Publ., New York.

Armstrong, B., and Doll, R.,(1975). Int. J. Cancer. 15: 617.

Fuchs, J.A., (19891, Glutaredoxin. In: Glutathione

Chemical, Biological and Medical Aspects, Part B, pp.

551-570. Editors: D. Solphin, 0. Avramovic and R. Poulson,

Wiley, New York.

Schmalbach, T.K., and Borch, R.F., (1989), Cancer

Res. 49: 6629-6633.

Allan, S.G., Cornbleet, M.A., Warringtton, P.S.,

Golland, I.M., Leonard, L.F., and Smyth, J.F.,(1984),

Br. Med. J. 289: 878-879.

Preifle, C.E., Howell, S.B., Fe1 thouse,R. D., Woliver,

T.B.S., Andrews, P.A., Markman, M., and Murphy, M.P.,

(1987), J. Cl in. Oncol. 3.237-244.

Rothenberg, M.L., Ostchega, Y., Steinberg, S.M., You~~g,

R.K., Hummo, S., and Ozols, R. F., (19881, Cancer J.

Natl. Cancer Inst. 80: 1488-1492.

Brock, N.G., and Pohl, J., (19841,Cancer Treat. Rev. 11:

(Suppl) 111.

Colvin, M., (1982) The alkylating agents.In: Chamber.B. ed!

Philadelphia, W.B., Sounders Co. 294-298.

302. Philip, L.T., Yuhan, J.M., and Wasserman, T.A.,11986),

Ind. J. Exp. Biol. 24: 767-770.

303. Yuhas, J.M., Spellman, J.M., and Culo, F., (1980),

Cancer Cl inical Trial S. 3: 211-218.

304. Litterst, C.L., Bertolero, F., and Uozumi, J. (19851,

In. MC Brien, D.C.H., Slater, eds. Biochmical Mechanisms

of Platinum Antitumour drugs, P.P.227-248 oxford:IRL Press.

305. Arrick, B.A., and Nathan, C.F., (1984), Cancer Res. 44:

4224-4232.

306. Abe, M., Hiraoka, M,, Takahoshi, M., Ono, K., Nohar, H.,

( 1982) ,~atj. Cancer Inst. Monogr . 61: 411-414.

307. Hall, R.R., schade, R.O.K., Swineey, J., (1974),

Br. Med. J. 2: 593-594.

308. Caveliere. R., Ciocatto, E.C., Giovanella, B.C.,

Heidelberger, C., Johnson, R.O., Margottini,

M., Mondovim,B., Moricca, G., (1967), Rossi-Fanelli,A.

Cancer.20: 1351-1381.

309. Meyn, R.E., Cary, P.M., Fletcher, S.E., and Demetriades,

M., (1980), Cancer Res. 40: 1136-1139.

310. Wallach, D.F.H., (19711, J. Mol. Med,2:381-403.

311. Mondavi, B . , Strom,R., R o t o l i o , G . , Agro, A.F.,

C a v a l i e r e , R . , and F e n e l l i , A . R . , ( 1969) ,

Eur. J . Cancer. 5: 129-136.

312. Leeper, D.B., ( 1 9 8 6 ) , Hyperthermia Oncol. 2 : 9-40.

313. Sudhir Agarwal., and MFrsa, K . , ( 1980) , P l an t a Medica.

38: 277.