Best Autism Treatment in Chennai

7/28/2019 Best Autism Treatment in Chennai

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DOAST- NPK- Chennai- INDIA 1


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DOAST Integrated TherapySuccessful in-vivo techniquein synergy with Global research.Treatment Guided research

which

Follows the LEADS and focuses onsafe and effective interventions



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Dr.Bernaud Rimland

Authored the Neurobiological

approach.

The First

POSITIVE TURN IN

AUTISM RESEARCH

Four decades of Global Research.

Are we able to deliver peace at home?


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Autism research exhibits analytical

threads, but patterns remain

fragmented lacking a unified concept.

As on date we lack a coherent view on

brain function within the framework of

other organ systems.



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POSITIVE APPROACH of DOASTInstead of studying it through a

symptom by symptom approach,

autistic behavior should beunderstood better by studying the

underlying intermediary biological

processes



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Emerging qualitative changes inclinical status including loss of

diagnosis suggest that a more

appropriate description for ASD couldbe a chronic dynamic reversible

encephalopathy rather than static

encephalopathy as considered so far.



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Cognitive, emotional and synaptic

functions of the brain basically rely onthe macromolecular computing system

ofRNA protein- and protein to protein

interactions which appear to be theresult of fine grained information,

encoded and accumulated over

evolutionary time.DOAST- NPK- Chennai- INDIA 7


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Neuro-Endo-Immune-GI Tract Network,

Autonomic Balance,

&Neurotransmitters.


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Bio feed back &

Autonomic Balance

CNS-ENDO-IMMUNE-GI

Tract- Network

Homeostasis

Normal

Performance

Social&Cognitive,Activities

Genes,

Molecular order,

Protein expression,

Nerurotransmitters

Neuronal connectivity.

Behavior&Cognitive

dysfunction.

Altered

network

Homeostasis

SusceptibleGenetic

landscape

Downstream

Systemic

Inflammation

Upstream

molecular

unrest


AUTISM


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Decreased connectivity is at the heart ofautism.Fairly close regions of the brains involved in

motor tasks have difficulty coordinating

activity.It makes sense that social and communication

skills are greatly impaired, as they involve

more complex synchronous coordinationbetween more distant areas of the brain.



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Consequences of inflammatory factors

Breaking boundaries between the bodyand brain,

Destabilization and loss of synapticconnections.



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Upstream

molecular

unrestDown streaminflammationDietary or environmentaltriggers,Gut micro biomesystemic inflammatorycytokines on a chronic basis

Our Concept..

Synaptic

connectivity

affected in insusceptible

individuals.


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Bio feed back &

Autonomic Balance

CNS-ENDO-IMMUNE-GI

Tract- Network

Homeostasis

Normal

Performance

Social&Cognitive,

Activities

Genes,

Molecular order,

Protein expression,

Nerurotransmitters

Neuronal connectivity.

ImprovedBehavior&

Cognition

Restore

NetworkHomeostasis

Cellular

Stressors

DownstreamMolecular

order

Upstreammolecular

order


INTEGRATED

THERAPY

Integrated Therapy Hypothesis


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Deviate from the Hard wired concept and

untreatable stigma.

Effectively treating the downstream inflammatory

pathology could initiate reestablishment ofupstream

molecular order . Molecular order restored could

activate the dormant neuronal pools, improveconnectivity and restore functional integration.



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DOAST Integrated therapy

Pioneering concept of therapeutic integration orfusion, where scientifically chosen traditional

Indian treatment methods are applied with modern

medical understanding to treat specific chronicailments, and autism in particular.

DOAST- NPK- Chennai- INDIA


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The Components of Integrated Therapy.

The Science of Yoga, Ayurveda &Siddha &

Modern medical expertise.

DOAST- NPK- Chennai- INDIA


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Reducing Cellular stress

Toxin elimination

Rejuvenation and

Regeneration.



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No reliable bio-marker.

Observed improvements in behavior

and cognition domains are the onlyreliable non-invasive indicators of

restoration of molecular order and

integration of the upstream neuronalpools.


Prognostic Evaluation


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Patient selection.

DSM-IV guidelines, (CARS) and M-CHAT arethe standard assessment tools used.

Patient pool represents a spectrum of severity

observed in autistic patients in general.

Their racial origin is Asian. Age 3- 16 years.

Cohort of 30 individuals on different follow upperiod on this therapy since 2004.


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Therapeutic protocol

The prescribed diet SathvikDiet practiced by

the science Yoga.

Herbal medications, certified by the Ayurvedic

[including Siddha] pharmacopia of India areadministered.

Yoga technique is a combinatorial approach.

Oleation therapies with medicated oils.



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Ethical & safety guidelines followed

A well informed consent, The therapy techniques and medicines are chosen

by evidence based risk benefit ratio, proven over

centuries in their clinical application,

One to one & Group basis application along with

the parent,

Documentation on paper and video,

Pretreatment EEG and periodic monitoring ofbiochemical parameters to assess renal, hepatic

and hematological functions.



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Assessment of Clinical benefits

Eye contact,

Play,

Communication,

Empathy & Generalization

are the behavior domains

chosen to assess and

quantify behavior andcognitive improvement.


GI Tract,

Respiratory,

Sleep,

Morbidity,

Emotions,

Behavior,Cognition.

C


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Controls We follow each patient, from the time of admission and

through their recovery (or lack of it). Thus each participant

in the study will serve as his/her own control.

Improvement is influenced by the age of induction into

therapy, duration of follow-up and compliance to the details.

Parental compliance to be proportional to the trust on

therapy.

Willful or accidental default in medicine or dietary regime

'influenced by the above listed variables', resulted intemporary return of symptoms. Such events helped us

understand the therapeutic role played by components of

therapy in a better way.



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VALIDITY

Consistent replication lends validity,

Supports the hypothesis that chronicinflammation could indeed be the common

denominator.


Future research

We contemplate generating carefully characterized full

genome expression profiling data to validate our

biomedical approach and to study the involvement ofthe intestinal flora in the inflammation related etiology

of autism.


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The core of our study will be a repeated

measures examination of the interplay

between the biology of inflammatory and

oxidative stress markers on the one hand

and processing, connectivity and reactivity

abnormalities on the other which may

conceivably converge on to the autism

profile.



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Proposed StudyExamine the gastrointestinal

metagenomic analysis of intestinal

flora,Non-coding RNA (ncRNA) expression

profiles on lymphoblasts in a series of

before and after comparison basedmolecular studies.



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Outcome of the proposal

Generate direct evidence in favor of a causal

relationship between systemic inflammation and

autism,

Generate diagnostic determinants for definitionof this variant of autism,

Define a link between diagnostics and treatment

by this and any future treatment technique.



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In the least invasive manner, using thisDOAST treatment modality as a

physiological probe, we study the linear,

causal relationship between cellular-levelchanges and behavioural problems within

the high performance environment of the

human nervous system.



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The identification of relationships between

the multiple levels, all of which can be

expected to shift based on both huge

amounts of clinical experience and a

growing wealth of published scientific

data, will be a contribution to identifying

treatment targets that simultaneously

address multiple features of autism at theirroot.



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While there are risks associated with any dogma

challenging proposal, the most compelling gains

of this project is that success in any of the

multiple facets of this investigation will lead to

important new knowledge about epigenetic and

molecular denominator based integratedtherapeutic approaches for a heterogeneous

neural disorder that has so far not responded

significantly to mono therapy.



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Best Autism Treatment in Chennai