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Bell Ringer (eggs up front)Observe what happened to the eggs.
Did you expect this to happen?Think about it in terms of fluid
movement.
Plasma Membrane: Structure
http://trixyofassisi.blogspot.con/2012/01/plasma-membranes.html
Lesson OverviewShort VideoGroup ExplorationBrief LectureMembrane ModelingReview
http://youtu.be/Qqsf_UJcfBc
Think, Pair, ShareRead the brochure on the plasma
membrane with the person next to you.
Take note of several key components
of the membrane.
Discuss and decide on a favorite destination with your neighbor. We will share in a moment.
Fluid Mosaic ModelCell Membrane is a mosaic
Proteins and other molecules are embedded in a framework
Cell Membrane is fluidMost protein and phospholipid molecules can move laterally
Membrane Structure
Phospholipids are the major structural component of membranes.
Phospholipid
Membrane StructureAll membranes are phospholipid bilayers
with embedded proteins.
Hydrophilic heads
Hydrophobic tails
Phospholipid Bilayer
Glycoproteins & Glycolipids Have short chain carbohydrates
attached on the outer side of the membrane.
Cell-cell recognition - identify type of cell and identify a cell as “self” vs. foreign
Membrane Proteins:integral proteins – embedded in the
membrane Peripheral proteins – not embeddedExamples:
channels and carriersenzymesreceptor proteins
Transport Proteins Passive Transport
Allows substances to cross the membrane by diffusionDiffusion - movement from high concentration to low concentration
no energy required
Active Transport Requires energy (ATP) to transport
substances against their concentration gradient
LE 7-17
Diffusion Facilitated diffusion
Passive transport
ATP
Active transport
Active Transport
Channel Carrier
More about Active Transport
Vesicle forming
Endocytosis
EndocytosisCell membrane sinks inward, pinches off and forms a vesicle
Brings material into the cell
Endocytosis - termsPhagocytosis – cell eating
Brings in solid particlesExamples: bacteria, cell debris, or food
Pinocytosis – cell drinkingCell brings in a liquid
Vesicle
Fluid outside cell
Protein
Cytoplasm
ExocytosisMovement of large molecules
out of the cell.
BE the Plasma MembraneUse your amazing
interpretive dance skills to BE the membrane.
The entire class will BE the membrane and model what a fellow classmate (the director) dictates. Hint: Hydrophobic arms
Fig. 5-1a
Cholesterol
Glycoprotein
Glycolipid
Carbohydrate ofglycoprotein
Phospholipid
Microfilamentsof cytoskeleton
Protein
Murky and Main PointsWrite 3 main points from today’s lesson.
Must be content-based. Ex: The plasma membrane is selectively
permeable to control what is allowed in and out of the cell.
Write 1 or more murky points from today’s lesson. This is material that is unclear to you.
Write 1 favorite point from today’s lesson. What did you enjoy about class today?
ProblemWhy is the structure of the plasma membrane beneficial for:The Environment Functions of the cell
ReviewThe plasma membrane is made of a
phospholipid _______.The phospholipids have a hydrophilic
______ and two hydrophobic _____.When ___________ is present in the
cell membrane, its presence stabilizes the membrane and hinders packing at cold temperatures.
head
bilayer
tails
cholesterol
ReviewProteins that penetrate the bilayer are
called _________ proteins. Many of these are _______________
proteins, because they completely span the membrane.
___________ proteins are not embedded in the lipid bilayer.
When carbohydrates covalently bond to proteins they are called _____________, which play a role in cell-cell recognition.
Peripheral
integral
transmembrane
glycoproteins
Review________ proteins allow hydrophilic
molecules to quickly pass from one side of the membrane to the other.
_______ proteins alternate between two conformations for molecules to be transported.
Channel
Carrier