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    Behavioral Treatment of Obesity inChildren and Adults:

    v ence- ase n erven ons

    Hollie Raynor, Ph.D., R.D., L.D.N.Hollie Raynor, Ph.D., R.D., L.D.N.

    Associate ProfessorAssociate ProfessorDepartment of NutritionDepartment of Nutrition

    Obesity Research CenterObesity Research Center

    Objectives

    Define evidenceDefine evidence--based treatmentbased treatment

    --based childhood obesity interventionsbased childhood obesity interventions

    Describe the components of evidenceDescribe the components of evidence--based adult obesity interventionsbased adult obesity interventions

    en y e ec ve e ary nerven onsen y e ec ve e ary n erven onsused in adult behavioral weight controlused in adult behavioral weight controlinterventionsinterventions

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    What is Evidence-based? The focus on using evidenceThe focus on using evidence--basedbased

    n erven ons comes rom concerns an erven ons comes rom concerns apatients/clients receive treatment that ispatients/clients receive treatment that isgrounded in tradition and/or outdated training,grounded in tradition and/or outdated training,rather than scientific evidencerather than scientific evidence

    esearc commun y encourage oesearc commun y encourage oscrutinize and evaluate interventions in orderscrutinize and evaluate interventions in orderto ascertain their efficacyto ascertain their efficacy

    What is Evidence-based?

    Accumulation of researchAccumulation of research

    Quality of researchQuality of research Experimental vs. Observational designsExperimental vs. Observational designs

    MethodsMethods

    Measures (selfMeasures (self--report vs. objective)report vs. objective)

    Randomized Controlled TrialsRandomized Controlled Trials

    MetaMeta--analysesanalyses

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    What is Evidence-based? --

    Current best evidence for making clinicalCurrent best evidence for making clinicaldecisions about the care of patients/clientsdecisions about the care of patients/clients

    Incorporates best research evidence,Incorporates best research evidence,clinical expertise, and patient valuesclinical expertise, and patient values

    Currentl used to im rove the ualit ofCurrentl used to im rove the ualit ofcare, and can provide objective criteria forcare, and can provide objective criteria for

    decisions regarding the allocation of healthdecisions regarding the allocation of healthcare resourcescare resources

    What is Evidence-based?

    LimitationsLimitations

    Understanding efficacy (emphasis onUnderstanding efficacy (emphasis oninternal validity) vs. effectivenessinternal validity) vs. effectiveness(emphasis on external validity)(emphasis on external validity)

    Type of population studiedType of population studied

    Geographic settingsGeographic settings

    Health care settingHealth care setting

    Will change over timeWill change over time

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    Overweight/Obese - definition

    Definitions of overweight and obese are based uponDefinitions of overweight and obese are based upon bodybodymass index (BMI):mass index (BMI): weight (kg)/height (mweight (kg)/height (m22))

    In children,In children, BMI percentileBMI percentile for age and gender is thefor age and gender is thepreferred measure for detecting overweight in childrenpreferred measure for detecting overweight in childrenand adolescentsand adolescents

    Overweight (at risk for overweight):Overweight (at risk for overweight): 8585thth to 94to 94thth ercentile BMIercentile BMI

    Obese (overweight):Obese (overweight): >>9595thth percentile BMIpercentile BMI

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    Overweight/Obese - definition

    ,,classified by BMIclassified by BMI

    BMIBMI >>25 = overweight25 = overweight

    BMIBMI >>30 = obese30 = obese

    BMIBMI >>40 = extreme obesity40 = extreme obesity

    Body Mass Index Table

    BMI =25BMI =25 BMI =30BMI =30

    InchesInches Body weight (lbs)Body weight (lbs)

    6060 129129 153153

    6161 133133 158158

    6262 137137 164164

    6363 142142 169169

    6464 146146 174174

    6565 151151 180180

    6666 155155 186186

    6767 160160 191191

    6868 165165 197197

    6969 170170 203203

    7070 175175 209209

    7171 180180 215215

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    Goals of Behavioral Lifestyle

    Interventions

    Behavioral lifestyle interventions focus onBehavioral lifestyle interventions focus onc angngc angng ea ngea ng anan e suree sure-- me ac v yme ac v ybehaviorsbehaviors

    Goal is to:Goal is to:

    Improve weight statusImprove weight status Weight loss in adultsWeight loss in adults

    Maintain weight statusMaintain weight status

    Long term weight loss maintenanceLong term weight loss maintenance Weight gain preventionWeight gain prevention

    Behavioral Lifestyle Interventions

    LeisureLeisure--time activity goalstime activity goals

    Behavioral modification techniquesBehavioral modification techniques

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    Behavioral Theory

    EvidenceEvidence--based childhood and adult obesitybased childhood and adult obesity

    Antecedents Behaviors ConsequencesAntecedents Behaviors Consequences

    The interventions use behavior modificationThe interventions use behavior modification

    -2

    0

    2

    -8

    -6

    -4

    Weightloss(kg) vce uca on

    Diet (behavioral intervention)

    Diet +exercise (behavioral

    intervention)

    -10

    0 6-mo 12-mo 24-mo

    Months

    Franz MJ et al. Weight-loss outcomes: a systematic review and meta-analysis of weight loss clinical

    trials with a minimum 1-year follow-up. JADA 2007;107:1755-67.

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    ADA-Evidence Analysis Library Pediatric weight managementPediatric weight management

    Using behavioral counseling as part of aUsing behavioral counseling as part of amultimulti--component pediatric weightcomponent pediatric weightmanagement (PWM) program to treatmanagement (PWM) program to treatoverweight results in significant reductionsoverweight results in significant reductionsin weight status and adiposity in childrenin weight status and adiposity in childrenan a o escen s.an a oescen s.

    Rating: Grade I (good)Rating: Grade I (good)

    ADA-Evidence Analysis Library

    pediatric obesity in children andpediatric obesity in children andadolescent obesity treatmentadolescent obesity treatment

    Family participationFamily participation Children (6Children (6--12 yrs)12 yrs) Rating: Strong (Imperative)Rating: Strong (Imperative)

    Rating: Fair (conditional)Rating: Fair (conditional)

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    ADA-Evidence Analysis Library

    What about younger children?What about younger children?

    No ratin s as ver little research has beenNo ratin s as ver little researchhas beenconducted in this age groupconducted in this age group

    Given the evidence for children aged 6 to 12 yrs,Given the evidence for children aged 6 to 12 yrs,most likely intervention should be familymost likely intervention should be family--basedbased

    Effectiveness aside, weight loss (in contrast toEffectiveness aside, weight loss (in contrast toweight management) in this population may beweight management) in this population may beappropra e ony un er cer an crcums ances.appropra e ony un er cer an crcums ances.However, these circumstances have not beenHowever, these circumstances have not been

    identified in the research.identified in the research.

    ADA-Evidence Analysis Library

    -- ,,kcal per day) as part of a clinicallykcal per day) as part of a clinicallysupervised, multisupervised, multi--component weightcomponent weight--loss program is associated with bothloss program is associated with bothshortshort--term and longerterm and longer--term reduction interm reduction inadi osit amon sixadi osit amon six-- to 12to 12-- eaea --oldoldchildren.children. Rating: Grade I (good)Rating: Grade I (good)

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    ADA-Evidence Analysis Library

    component of a clinically supervised,component of a clinically supervised,multimulti--component childhood weightcomponent childhood weight--management intervention program.management intervention program.

    Rating: Grade I (good)Rating: Grade I (good)

    Childhood Obesity Interventions

    > 85> 85thth percentile BMI, but not greaterpercentile BMI, but not greaterthan 100% overweightthan 100% overweight

    Conducted in research settingsConducted in research settings

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    Behavioral Targets

    EvidenceEvidence--based interventions targetbased interventions targetbehaviors that reduce energy intake andbehaviors that reduce energy intake andincrease energy expenditureincrease energy expenditure

    LowLow--calorie diet (900calorie diet (900--1200 kcals/day)1200 kcals/day) Most widely studied is the Traffic Light Diet (Epstein andMost widely studied is the Traffic Light Diet (Epstein and

    colleagues)colleagues)

    Categorizes food into Green, Yellow, Red (based uponCategorizes food into Green, Yellow, Red (based uponenergyenergy--density and nutrient quality)density and nutrient quality)

    e uce n a e o ase uce na e o as -- oo , so a, swee an sa y snacoo , so a, swee an sa y snacfoodsfoods

    Generally does not cause an increase in F&V and dairyGenerally does not cause an increase in F&V and dairyproducts unless specifically targeted in treatmentproducts unless specifically targeted in treatment

    Behavioral Targets

    --

    Increase in physical activity (60 minutes/day),Increase in physical activity (60 minutes/day),with focus on play and family activitieswith focus on play and family activities

    Reduction in TV watching (Reduction in TV watching (

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    Riley et al., 2008

    FamilyFamily--based is not just includingbased is not just includingparents/caregivers in the treatment ofparents/caregivers in the treatment of

    ''

    Changing the context of the family (home)Changing the context of the family (home)environment to help support the change aenvironment to help support the change achild is making:child is making:

    ParentingParenting

    CommunicationCommunication

    SupportSupport

    EnvironmentEnvironment

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    Behavioral Parenting Program Strategies for Antecedents:Strategies for Antecedents:

    -- aren a mo e ngaren a mo e ng Parent makes all of the same changes in behaviors asParent makes all of the same changes in behaviors as

    childchild

    -- Change the home environment (stimulus control)Change the home environment (stimulus control) EatingEating

    -- Overt and covert restrictionOvert and covert restriction

    --

    -- ProblemProblem--solving and presolving and pre--planningplanning

    Behavioral Parenting Program

    Strategies for behaviors:Strategies for behaviors: --

    Goals of programGoals of program Kcals, Red Foods, F&VKcals, Red Foods, F&V Physical ActivityPhysical Activity TV WatchingTV Watching WeightWeight

    ParentParent--child meetingschild meetings

    Tie weight change to behavior change toTie weight change to behavior change to

    weightweight Feedback on selfFeedback on self--monitoring is importantmonitoring is important

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    Behavioral Parenting Program Strategies for consequences:Strategies for consequences:

    Positive reinforcementPositive reinforcement

    PraisePraise

    Contingency contractingContingency contracting

    Point systemPoint system

    Reduction of negative reinforcementReduction of negative reinforcement

    Increase use of extinction for problematicIncrease use of extinction for problematic

    behaviorsbehaviors

    FamilyFamily--based:based:

    Group processGroup process

    Treatment Structure

    CogntveCogntve-- e avorae avora

    Social learning (Interventionist serves as model ofSocial learning (Interventionist serves as model ofparenting behaviors)parenting behaviors)

    Sessions:Sessions:

    Review of assigned homework (group process andReview of assigned homework (group process and

    Presentation and discussion of new topic (cognitivePresentation and discussion of new topic (cognitivebehavioralbehavioral parenting behaviors/practices)parenting behaviors/practices)

    Assignment of new homeworkAssignment of new homework

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    Treatment Structure 66--months of treatment (Parent + child)months of treatment (Parent + child)

    Weekly sessions for 12 to 16 weeksWeekly sessions for 12 to 16 weeks Group session for parentsGroup session for parents

    Group session for childrenGroup session for children

    15 minute individual parent15 minute individual parent--child meeting with anchild meeting with aninterventionistinterventionist

    For remaining 2 to 3 months of treatment,For remaining 2 to 3 months of treatment,frequency of sessions drops to either one or twofrequency of sessions drops to either one or twomeetings/monthmeetings/month

    Assessments at 0, 6, 12 months (DV =Assessments at 0, 6, 12 months (DV =

    percent overweight or zBMI)percent overweight or zBMI)

    Childhood Obesity Treatment

    These evidenceThese evidence--based interventions targetingbased interventions targetingc ren age o years pro ucesc ren age o years pro ucessignificant reductions in percent overweightsignificant reductions in percent overweight((--15 to15 to --20%), with 1020%), with 10--year followyear follow--up showingup showingalmost 1/3 of treated children no longeralmost 1/3 of treated children no longeroverweight and a mean reduction in percentoverweight and a mean reduction in percent

    -- ,,Paluch, & Raynor, 2002; Epstein, Paluch, Kilanowski, Raynor,Paluch, & Raynor, 2002; Epstein, Paluch, Kilanowski, Raynor,2004; Raynor,2004; Raynor, Kilanowski, Esterlis, & Epstein, 2002 )Kilanowski, Esterlis, & Epstein, 2002 )

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    Maternal and Child Health Bureau

    Recommendations for Treatment in a

    Primary Care Setting

    ..

    years of ageyears of age

    2. Apply a family2. Apply a family--based model in treatmentbased model in treatment

    3. Use behavior modification techniques3. Use behavior modification techniques

    4. Help families make small changes4. Help families make small changes

    5. Target changing 2 or 3 eating and activity5. Target changing 2 or 3 eating and activity

    behaviors at a timebehaviors at a time

    Childhood Interventions Behaviors recommended to target in primary careBehaviors recommended to target in primary care

    settingssettings

    FastFast--food intake (limit)food intake (limit)

    Sweetened drink intake (limit)Sweetened drink intake (limit)

    Sweet and salty snack foods (limit)Sweet and salty snack foods (limit)

    LowLow--fat dairy (2 servings per day)fat dairy (2 servings per day)

    Fruits & vegetables (1.5 c fruits & 2.5 c vegetables/day)Fruits & vegetables (1.5 c fruits & 2.5 c vegetables/day)

    Physical activity (60 minutes per day)Physical activity (60 minutes per day) TV watching (< 2 hrs/day)TV watching (< 2 hrs/day)

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    Childhood Interventions

    Will these recommendations beWill these recommendations beeffective at treating young children whoeffective at treating young children whoare overweight?are overweight?

    ANDAND

    What are the best behaviors to target?What are the best behaviors to target?

    Pediatric Obesity Treatment Child HELP and Kids CANChild HELP and Kids CAN

    Two research programs funded by theTwo research programs funded by theAmercan D a etes Assoc aton an t eAmercan D a etes Assoc aton an t eNational Institutes of HealthNational Institutes of Health

    For children between the ages of 4 to 9For children between the ages of 4 to 9years,years, >>8585thth percentile BMI, with at leastpercentile BMI, with at least

    one problematic eating or activity behaviorone problematic eating or activity behavior

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    Pediatric Obesity Treatment Both programs randomly assign families toBoth programs randomly assign families to

    one o ree, mon n erven onsone o ree, mon n erven ons

    Behavioral parenting program (2 differentBehavioral parenting program (2 differentparenting programs in each study)parenting programs in each study)

    NewsletterNewsletter

    Anthropometric assessments conductedAnthropometric assessments conducted--

    feedback to families and pediatricianfeedback to families and pediatrician

    Child HELP

    IncreaseIncrease

    Fruits and VegetablesFruits and Vegetables

    (2 servings fruit and 3(2 servings fruit and 3servings vegetables/day)servings vegetables/day)

    LowLow--fat dairyfat dairy

    (2 servings/day)(2 servings/day)

    LowLow--energyenergy--dense foodsdense foods

    Sweet/salty snack foodsSweet/salty snack foods

    ((

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    2

    2.2

    2.4

    2.6

    2.8

    0.4

    0.6

    0.8

    1

    1.2

    1.4

    1.6

    1.8

    zBMI Newsletter

    Increase

    Decrease

    0

    0.2

    0 6 12

    Months

    Kids CAN

    Physical ActivityPhysical Activity

    (60 min/day)(60 min/day)

    Sweetened drinksSweetened drinks

    ((

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    1.8

    2

    2.2

    2.4

    2.6

    0.4

    0.6

    0.8

    1

    1.2

    1.4

    1.6

    zBMI Newsletter

    Traditional

    Substitute

    0

    0.2

    0 6 12

    Months

    Important Components of Treatment Measures of weight statusMeasures of weight status

    Provides regulatory feedbackProvides regulatory feedback

    Children that do better have parents that are doingChildren that do better have parents that are doing

    betterbetter SelfSelf--monitoringmonitoring ModelingModeling Stimulus controlStimulus control PrePre--planning, problemplanning, problem--solvingsolving

    Pro rams that tar et arents onl also show oodPro rams that tar et arents onl also show oodoutcomesoutcomes

    Caloric prescription appears to be needed toCaloric prescription appears to be needed toproduce clinically relevant weight statusproduce clinically relevant weight statusimprovementsimprovements

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    ADA-Evidence Analysis Library

    Weight loss and weight maintenanceWeight loss and weight maintenance

    therapy should be based on atherapy should be based on acomprehensive weight managementcomprehensive weight managementprogram including diet, physical activity,program including diet, physical activity,and behavior therapy. The combinationand behavior therapy. The combination

    erapy s more success u an usng anyerapy s more success u an usng anyone intervention alone.one intervention alone. Rating: StrongRating: Strong

    ADA-Evidence Analysis Library

    A com rehensive adult wei ht mana ement ro ramA com rehensive adult wei ht mana ement ro ramshould make maximum use of multiple strategies forshould make maximum use of multiple strategies forbehavior therapy (e.g. self monitoring, stressbehavior therapy (e.g. self monitoring, stressmanagement, stimulus control, problem solving,management, stimulus control, problem solving,contingency management, cognitive restructuring,contingency management, cognitive restructuring,and social support). Behavior therapy in addition toand social support). Behavior therapy in addition todiet and physical activity leads to additional weightdiet and physical activity leads to additional weightloss. Continued behavioral interventions ma beloss. Continued behavioral interventions ma benecessary to prevent a return to baseline weight.necessary to prevent a return to baseline weight. Rating: StrongRating: Strong

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    Adult Obesity Treatment ,,

    treatments achieve a mean weight loss of 10treatments achieve a mean weight loss of 10kg over 6 months of treatment, but have akg over 6 months of treatment, but have aweightweight--loss regain of 38% over a mean f/u ofloss regain of 38% over a mean f/u of18 months (Wing, 2002)18 months (Wing, 2002)

    How can weight loss maintenance beHow can weight loss maintenance be

    improved?improved?

    Adult Obesity Interventions

    LowLow--calorie diet (1200calorie diet (1200--1500 kcals/day)1500 kcals/day)

    LowLow--fat diet (20% to 30% kcals/fat)fat diet (20% to 30% kcals/fat)

    Strong focus on increasing structure of the dietStrong focus on increasing structure of the diet

    Physical activityPhysical activity

    --10,000 steps/day10,000 steps/day

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    Behavior Modification Strategies for Antecedents:Strategies for Antecedents:

    -- ange e ome envronmen s muusange e ome envronmen s muuscontrol)control)EatingEating

    LeisureLeisure--time behaviorstime behaviors

    -- ProblemProblem--solving and presolving and pre--planningplanning

    --

    -- Cognitive restructuringCognitive restructuring

    -- RelaxationRelaxation

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    Behavior Modification Strategies for behaviors:Strategies for behaviors:

    SelfSelf--monitoringmonitoringGoals of programGoals of program

    Kcals, fatKcals, fat

    Physical ActivityPhysical Activity

    WeightWeight

    Tie weight change to behavior change toTie weight change to behavior change toemonstrate reatons p etweenemonstrate reatons p etween

    behaviors and weightbehaviors and weight

    Feedback on selfFeedback on self--monitoring is importantmonitoring is important

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    Behavior Modification Strategies for consequences:Strategies for consequences:

    Positive reinforcementPositive reinforcement

    Weight loss vs. maintenanceWeight loss vs. maintenance

    Reinforcing value of foodReinforcing value of food

    Structure of Treatment

    outcomes, standard length of intervention isoutcomes, standard length of intervention is18 months18 months

    Weight loss interventionsWeight loss interventions Weekly for 6 monthsWeekly for 6 months 60 minute group sessions60 minute group sessions

    2 times/month for months 72 times/month for months 7--1818 -- 60 minute group60 minute group

    sessonssessons Assessments at 0, 6, 12, 18 months (DV =Assessments at 0, 6, 12, 18 months (DV =

    wt)wt)

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    Important Components of

    Treatment Measures of wei ht statusMeasures of wei ht status

    Provides regulatory feedbackProvides regulatory feedback

    Regular and longRegular and long--term followterm follow--upup AccountabilityAccountability

    Habit changeHabit change

    SelfSelf--monitoringmonitoring

    Dietary structureDietary structure Meal plans, meal replacements, portion controlled foodsMeal plans, meal replacements, portion controlled foods

    Variety?Variety?

    Lots of physical activity!Lots of physical activity!

    Materials from DPP

    . . .. . .p_part.htmlp_part.html

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    Macronutrient Content

    of the Diet

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    Macronutrient Composition

    and Weight Loss Maintenance 800 artici ants800 artici ants Randomly assigned to 1 of 4 diets:Randomly assigned to 1 of 4 diets: the targeted

    percentages of energy derived from fat, protein,and carbohydrates in the four diets were 20, 15,and 65%; 20, 25, and 55%; 40, 15, and 45%; and40, 25, and 35% - diets consisted of similar foodsand met guidelines for cardiovascular health

    Received behavior modification, and had a

    physical activity goal of 90 min/week

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    Dietary Structure

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    Do meal replacements help with

    weight loss?

    Foods of fixed calorie and nutrient contentFoods of fixed calorie and nutrient contentthat are designed to take the place of a mealthat are designed to take the place of a mealor snackor snack

    PortionPortion--controlled and nutritionally balancedcontrolled and nutritionally balanced

    , , ,, , ,prepared mealsprepared meals

    Typical recommendation is to replace 2Typical recommendation is to replace 2meals with a meal replacementmeals with a meal replacement

    Do meal replacements help withweight loss?

    Purpose: To examine whether using mealPurpose: To examine whether using mealreplacements improves weight loss in adultsreplacements improves weight loss in adultsenrolled in a weight loss program.enrolled in a weight loss program.

    Participants: 100 overweight and obese menParticipants: 100 overweight and obese men

    diet groups.diet groups.

    Length of weight loss program: 27 monthsLength of weight loss program: 27 months

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    Do meal replacements help

    with weight loss?

    Diet A: 1200Diet A: 1200--1500 calories/day, with1500 calories/day, withparticipants eating regular foodsparticipants eating regular foods

    Diet B: 1200Diet B: 1200--1500 calories/day, with1500 calories/day, withparticipants using meal replacements for 2participants using meal replacements for 2meals and 2 snacks each daymeals and 2 snacks each day

    as mon s:as mon s:

    Both groups followed the same 1200Both groups followed the same 1200--15001500kcals/day diet and used meal replacementskcals/day diet and used meal replacementsfor 1 meal and 1 snack per dayfor 1 meal and 1 snack per day

    Weight Loss Maintenance Using

    Meal Replacements0

    ight

    4

    6

    8

    ereductionininitialw Standard then

    Meal

    Replacement

    10

    12Percentag

    TimeDitschuneit et al., AJ CN; 1999; 69: 198-204

    Meal

    Replacement

    0 2 4 6 8 10 12 14 16 18 20 22 24 26 28

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    Why are meal replacements

    effective for weight loss?

    ConvenientConvenient

    PortionPortion--controlledcontrolled

    Removes work of estimating portion size andRemoves work of estimating portion size andcaloriescalories

    Widely availableWidely available

    Easy to selfEasy to self--monitormonitor

    Dietary Variety

    with increased intake, weight, and bodywith increased intake, weight, and bodyfat in animals (for a review Raynor &fat in animals (for a review Raynor &Epstein, 2001, Psychological Bulletin)Epstein, 2001, Psychological Bulletin)

    Increased variet within a meal isIncreased variet within a meal isassociated with increased consumptionassociated with increased consumptionin humansin humans

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    HFF

    20

    30

    40

    50

    60

    70

    Percentvariety

    Before intervention

    After intervention

    Registry

    FOS

    20

    30

    40

    50

    60

    70

    Percentvariety

    LFM

    20

    30

    40

    50

    60

    70

    Percentvariety

    0 0

    10

    0

    10

    LFB

    10

    20

    30

    40

    50

    60

    70

    Percentvariety

    LFV

    10

    20

    30

    40

    50

    60

    70

    Percentvariety

    0 0

    Mean percent variety in 5 food groups for recent successful weight losers before and after a standard

    weight loss intervention (n=96), and registry participants (n =2237) (M +SEM).

    Raynor, H. A., J effery, R. W., Phelan, S., Hill, J . O., & Wing, R.R. (2005). Amount of foodgroup variety consumed in the diet and long-term weight loss maintenance. Obesity Research, 13, 883-890.

    Food Group Variety andObesity Treatment

    different foods, particularly energydifferent foods, particularly energy--densedensefoods, in the diet may help with successfulfoods, in the diet may help with successfulweight loss and longweight loss and long--term weight lossterm weight lossmaintenancemaintenance

    Limiting variety may be especially helpfulLimiting variety may be especially helpfulduring maintenance, when selfduring maintenance, when self--monitoring ofmonitoring ofintake is less consistentintake is less consistent

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    Dietary Variety Prescription 18 month trial testin the effectof limitin snack food18 month trial testin the effectof limitin snackfood

    variety (R01variety (R01 -- NIDDK)NIDDK)

    2 groups: Standard vs. Standard + variety2 groups: Standard vs. Standard + varietyprescriptionprescription Can this prescription be adhered to over the longCan this prescription be adhered to over the long--term?term?

    Will a greater length of time of limiting variety effect weightWill a greater length of time of limiting variety effect weightloss?loss?

    control)?control)?

    200 participants200 participants

    Research TeamProvidence, RIProvidence, RI Knoxville, TNKnoxvi lle, TN

    Rena Wing, Ph.D.Rena Wing, Ph.D. Betsy Anderson, M.S., R.D. L.D.N.Betsy Anderson, M.S., R.D. L.D.N.

    Chantelle Hart, Ph.D.Chantelle Hart, Ph.D. Ashlee SchochAshlee Schoch

    Elissa Jelalian, Ph.D.Elissa Jelalian, Ph.D. Lusi MartinLusi Martin

    Patrick Vivier, M.D.Patrick Vivier, M.D. Shannon Looney, M.P.H.Shannon Looney, M.P.H.

    Kathrin Osterholt, M.S.Kathrin Osterholt, M.S. Christen Mullane, M.A.Christen Mullane, M.A.

    Amanda FineAmanda Fine J ess Bachman, M.S., R.D., L.D.N.J ess Bachman, M.S., R.D., L.D.N.

    Allison MartirAllison Martir Emily Van Walleghen, Ph.D.Emily Van Walleghen, Ph.D.

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