Batool F. Kirmani, MD Reference Listscottandwhite.photobooks.com/PhysicianPDFs/Research/PHY000148.pdfBatool Kirmani ,Diana Mungall, ... Owais Khan, Amanda Williams, Ekokobe Fonkem,

Batool F. Kirmani, MD

Reference List Abstract

Management of Status Epilepticus in the Emergency Room and

Intensive Care Settings First Global Emergency Medicine meeting, Shenzen, China , June 14-20, 2014 2014

“Recent Advances in the Medical Management of Intractable Epilepsy”.

Fourth Annual World Congress of NeuroTalk, Xi’an , China May 23-25, 2013 2013

“Epilepsy and Concomittant Pseudoseizures: A Diagnostic Dilemma” Seventh International Conference on Interdisciplinary Social Sciences,

Barcelona, Spain , June 25-28, 2012. 2012

“Pediatric Epilepsy: Acute Seizure Management in Children and

Neonates”. Third Annual World Congress of NeuroTalk, Beijing , China May 18-20, 2012 2012

“ Epilepsy and Psychiatric Disorders” The 6th International Conference on Interdisciplinary Social Sciences , New Orleans, July 11-13, 2011.

2011

“Epilepsy Surgery” Second Annual World Congress of NeuroTalk,

Dalian, China May 23-25, 2011 2011

July 18, 2014 1


Reference List Abstract

“Role of aspartoacyclase during myelination: Implications in Canavan

disease”. First International Symposium on N-Acetyl Aspartoacyclase, September 13-14, 2004, National Institutes of Health, Bethesda, MD.

2004

Book Chapter

Batool Kirmani ,Diana Mungall, Jose Aceves, David Gavito, Richard

Phenis, and Daniel Cruz Psychogenic Non-Epileptic Spells (PNES). Book Chapter: In “ Epilepsy", ISBN 980-953-307-1106-6 Editor Mark

Holmes , M.D 2014

Batool Kirmani Pediatric Epilepsy . In Pediatric Neurology. P.N Lawson

and EA McCarthy (Eds) . Nova Publishers Inc.Series: Neuroscience Research Progress . Pub. Date: 2011 4th quarter ISBN: 978-1-61470-

161-3 2011

Namboodiri MAA, Moffet JR, Arun P, Mathew R, Namboodiri SS, Potti A,

Hershfield JR, Kirmani BF, Jacobowitz DM, Madhavarao CN. Defective myelin lipid synthesis as a pathogenic mechanism of Canavan disease.

N-acetylaspartate : a Unique Neuronal Molecule in the Central Nervous System : [NAA, NAAG and Canavan''s disease: the First International

Symposium on N-acetylaspartate, Natcher Conference Center, NIH, Bethesda Maryland, September 13th and 14th, 2004] , pp. 145-163,

edited by Moffett, J., Tieman, S., Weinberger, D. R., Coyle, J. T., and Namboodiri, A. M. A. N.Y., Springer, Advances in Experimental

Medicine and Biology, v.576 ,Moffett, J., Tieman, S., Weinberger, D.

R., Coyle, J. T., and Namboodiri, A. M. A. 2006

Presentation

Khan OA, Chang EY, Cipriani CA, Wright CC, Crisp ED, Kirmani BF.

Experience with intravenous levetiracetam in preterm neonates. Presentation at the 63rd Annual Meeting of the Americn Academy of

Neurology, April 9-16, Honolulu, HI 2010

Khan OA, Chang EY, Wright CC, Cipriani CA, Crisp ED, Kirmani BF.

Role of intravenous levetiracetam in acute seizure management in neonates. Presented at the 64th Annual American Epilepsy society

Meeting, December 3-7, San Antonio, Tx. Epilepsia 0 Suppl. 0 (Abst. 1.105) 2010

July 18, 2014 2


Reference List Presentation

Mungall dH, Castillo R, Kirmani BF. Efficacy and tolerability of vimpat

in patients with epilepsy. Presentation at the 64th Annual American Epilepsy Society Meeting, December 307, San Antonio, TX. Epilepsia 0

Suppl. 0 (Abst. 1.105). 2010

Speeches

Batool F. Kirmani Management of Status Epilepticus in the Emergency

Room and Intensive Care Settings First Global Emergency Medicine meeting, Shenzen, China , June 14-20, 2014 Invited International Talk

2014

Batool F. Kirmani Epilepsy and Depression Eighth International

Conference on Interdisciplinary Social Sciences, Prague, Czech Republic , July 30- August 1, 2013. 2013

Batool F. Kirmani Recent Advances in the Medical Management of Intractable Epilepsy. Fourth Annual World Congress of NeuroTalk,

Xi’an ,China May 23-25, 2013 Invited International Talk 2013

Batool F. Kirmani Epilepsy and Concomittant Pseudoseizures: A

Diagnostic Dilemma Seventh International Conference on Interdisciplinary Social Sciences Barcelona, Spain , June 25-28, 2012.

2012

“ Epilepsy and Psychiatric Disorders” The 6th International Conference on Interdisciplinary Social Sciences , New Orleans, July 11-13, 2011.

2011

July 18, 2014 3


Reference List Speeches

“Epilepsy Surgery” World Congress of NeuroTalk, Dalian, China May

23-25, 2011 Invited International talk 2011

Batool F. Kirmani Pediatric Epilepsy: Acute Seizure Management in Children and Neonates World Congress of NeuroTalk, Beijing , China

May 18-20, 2012 Invited International talk 2011

Batool F. Kirmani 606 Epilepsy and Psychiatric Disorders The 6th

International Conference on Interdisciplinary Social Sciences , New Orleans, July 11-13, 2011. 2011

Batool F. Kirmani Epilepsy Surgery World Congress of NeuroTalk, Dalian, China May 23-25, 2011 Invited International talk 2011

In Press

Diana Mungall Robinson, Jose Aceves, M.D., Ekokobe Fonkem, D.O., Batool F. Kirmani Psychogenic Non-Epileptic Spells in Children Journal

of Neurological Diseases and Stroke 2014 2014

Joseph Pham, Darin Garret, Batool Kirmani , Sanjib Mukherjee ,

Eromata Ebwe, Soren Singel, and Ekokobe Fonkem, Role of Lacosamide in Seizure Control in Brain Tumor Patients Journal of

Neurological Diseases and Stroke 2014 2014

July 18, 2014 4


Reference List In Press

Jared F. Benge , J. Michael Therwhanger, and Batool F. Kirmani The

Neuropsychology of Frontal Lobe Epilepsy: A Selective Review of 5 Years of Progress Journal of Neurological Diseases and Stroke 2014

2014

Discussion

Future of Emergency Medicine Panel member- Round Table Discussion

First Global Emergency Medicine meeting, Shenzen, China , June 14-20, 2014 2014

Publications

Batool F. Kirmani Editorial: Role of Intravenous Levetiracetam in Acute Seizure Management Front. Neurol. doi: 10.3389/fneur.2014.00109

2014

Batool F. Kirmani Levetiracetam–An Alternative Option in Preterm

Neonates for Acute Seizure Management. Mol Cell Epilepsy 2014; Vol 1 No. 1 2014

Batool F. Kirmani Role of Intravenous Levetiracetam in Acute Seizure Management Front. Neurol. doi: 10.3389/fneur.2014.00109 2014

Batool F. Kirmani, Diana Mungall Robinson MD, Adeline Kikam BS, Ekokobe Fonkem MD, Daniel Cruz PsychD Selection of Antiepileptic

Drugs in Older People Current Treatment Options in Neurology, 2014 Vol 16, Issue 16, 1-16 2014

July 18, 2014 5


Reference List Publications

Benge JF, Michael TJ, Kirmani B The Neuropsychology of Frontal Lobe

Epilepsy: A Selective Review of 5 Years of Progress. J Neurol Disord Stroke 2(3):1057. (2014) 2014

Jose L. Aceves , Batool Kirmani , and Maria Blazo Congenital Lingual

Hemihyperplasia, Horner’s Syndrome, and Agenesis of the Internal Carotid Artery Pediatric Neurology 51 (2014) 176- 177 2014

Pham J, Garret D, Batool F. Kirmani, Fonkem E Role of Lacosamide in Seizure Control in Brain Tumor Patients. J Neurol Disord Stroke 2(3):

1056. (2014) 2014

Robinson DM, Aceves J, Fonkem E, Batool F. Kirmani Psychogenic Non-

Epileptic Spells in Children. J Neurol Disord Stroke 2(3): 1054. (2014) 2014

Role of Anticonvulsants in the Management of AIDS related Seizures Batool F. Kirmani and Diana Mungall Robinson Front. Neurol. doi:

10.3389/fneur.2014.00010 2014

Wenner A, Aceves J, Mungall D, Castillo R, Batool F. Kirmani Vagus

Nerve Stimulation for Medically Refractory Epilepsy in Children with Brain Malformations. JSM Clin Case Rep 2(2): 1029. (2014) 2014

July 18, 2014 6



Clinical Pharmacology and Pharmacokinetics of Levetiracetam Chanin

Clark Wright, Jana Downing, Diana Mungall, Owais Khan, Amanda Williams, Ekokobe Fonkem, Darin Garrett, Jose Aceves and Batool F.

Kirmani Front. Neurol. doi: 10.3389/fneur.2013.00192 2013

Batool F. Kirmani and Diana Mungall Importance of Video-EEG Monitoring in the Diagnosis of Refractory Panic Attacks Volume 2013

(2013), Article ID 340792, 3 pages 2013

Batool F. Kirmani Importance of Video-EEG Monitoring in the Diagnosis

of Epilepsy in a Psychiatric Patient Case Reports in Neurological MedicineVolume 2013 (2013), Article ID 159842, 2 pages

http://dx.doi.org/10.1155/2013/159842 2013

Batool F. Kirmani, Diana Mungall and Jose Aceves Management of

Lennox-Gastaut Syndrome with Rufinamide Journal of Pediatric Epilepsy 2 (2013) 109–113 DOI 10.3233/PEP-13049 IOS Press 2013

Batool F. Kirmani,. and Diana Mungall Efficacy and Tolerability of Vimpat in Patients with Intractable Epilepsy. The Internet Journal of

Neurology. 2013 Volume 15 Number 1. DOI: 10.5580/2cf2 2013

Batool F. Kirmani,. and Diana Mungall Epilepsy and Concomittant

Pseudoseizures: The Diagnostic Dilemma. The Internet Journal of Neurology. 2013 Volume 15 Number 1. DOI: 10.5580/2cf1 2013

July 18, 2014 7



Bernett A, Phenis R, Fonkem E, Aceves J, Kirmani B, Cruz-Laureano D.

Neurobehavioral effects of levetiracetam in brain tumor related epilepsy. Front Neurol. 2013 Jul 22;4:99. doi:

10.3389/fneur.2013.00099. Print 2013 2013

Aceves J, Khan O, Mungall D, Fonkem E, Wright C, Wenner A and Kirmani B Efficacy and tolerability of intravenous levetiracetam in

children. Front. Neurol. 4:120. doi: 10.3389/fneur.2013.00120 (2013)

2013

Efficacy and safety of extended-release oxcarbazepine (Oxtellar XR™) as adjunctive therapy in patients with refractory partial-onset seizures:

a randomized controlled trial. French JA, Baroldi P, Brittain ST, Johnson JK; PROSPER Investigators Study Group. Acta Neurol Scand.

2014 Mar;129(3):143-53. doi: 10.1111/ane.12207. Epub 2013 Dec

21. 2013

Owais A. Khan, Cheryl A. Cipriani, Chanin C. Wright, Edwin D. Crisp and Batool F. Kirmani Role of Intravenous Levetiracetam for Acute

Seizure Management in Preterm Neonates Pediatr Neurol. 2013 Aug 3.

doi:pii: S0887-8994(13)00331-7. 10.1016/j.pediatrneurol.2013.05.008. 2013

Neurobehavioral Effects of Levetiracetam in Patients with Traumatic

Brain Injury Jared F Benge, Richard Phenis, Abigail Bernett, Daniel Cruz and Batool F. Kirmani Front. Neurol. doi:

10.3389/fneur.2013.00195 2013

Sporadic hemiplegic migraine with ATP1A2 and prothrombin gene

mutations Jose Aceves , Diana Mungall and Batool F. Kirmani Case Reports in Neurological MedicineVolume 2013 (2013), Article ID

895057, 2 pages http://dx.doi.org/10.1155/2013/895057 2013

July 18, 2014 8



Role of Intravenous Levetiracetam in Seizure Prophylaxis of Severe

Traumatic Brain Injury Patients Batool F. Kirmani , Diana Mungall, Geoffrey Ling Mini Review, Front. Neurol. - Epilepsy, Submitted on: 26

Aug 2013 DOI: 10.3389/fneur.2013.00170 2013

The Role of Levetiracetam in Treatment of Seizures in Brain Tumor Patients Ekokobe Fonkem, Paul Bricker, Diana Mungall, Jose Aceves,

Eromata Ebwe, Wei Tang and Batool F. Kirmani Front. Neurol. doi:

10.3389/fneur.2013.00153 2013

Batool F. Kirmani and Edwin Darrell Crisp Selection and Evaluation of the Pediatric Epilepsy Surgical Candidates Current Pediatric Reviews,

Volume 8, Number 1, February 2012, Pp.66-70. 2012

Batool F. Kirmani Overview of Pediatric Epilepsy Current Pediatric

Reviews, Volume 8, Number 1, February 2012, Pp.59-65. 2012

Batool F. Kirmani. Mesial Temporal Sclerosis. Journal of Pediatric

Neuroradiology . Volume 1, Number 1, 2012 2012

Batool F. Kirmani., Gary Jones, D.O. and Edwin Darrell Crisp, M.D.

Retrospective Analysis Of Efficacy And Tolerability Of Keppra XR In An Outpatient Setting. The Internet Journal of Neurology. 2012 Volume

14 Number 1. DOI: 10.5580/2cb3 2012

July 18, 2014 9



Guest Editor: Batool F. Kirmani Editorial Hot Topic: Recent Advances in

Pediatric Epilepsy Surgery Current Pediatric Reviews, Volume 8, Number 1, February 2012, Pp.58-58. 2012

Lisa Ruiz and Batool F. Kirmani. Bilateral peripheral facial palsy as

early manifestation in a HIV patient. Case Reports in Neurological Medicine . 2012 Article ID 267405, 3pages doi:10.1155/2012/267405

2012

Owais A. Khan, Esther Y. Chang, Chanin C. Wright, Cheryl A. Cipriani,

Edwin D. Crisp and Batool F. Kirmani, Role of Intravenous Levetiracetum in acute seizure management in Neonates. Pediatr

Neurol. 2011 Apr;44(4):265-9. 2011



Neurol. 2011 Apr;44(4):265-9. 2011



Neurol. 2011 Apr;44(4):265-9. 2011

Strimel W, Woodruff A, Cheung PB, Kirmani BF, Huang SKS. Brugada-

like ECG pattern induced by lamotrigine toxicity. Clinical Neuropharmacology 33[5], 265-267. 2010

July 18, 2014 10



DeLorenzo RJ, Kirmani BF, Jakkampudi V, Towne AR, Waterhouse E,

Garnet L, Ko D. Comparisons of the mortality and clinical presentations of the mortality of status epilepticus in private and community hospital

settings. Seizure 18[6], 405-411. Epub 2009 Mar. 25 2009

Kirmani BF. Acute seizure management in children. Review. Pediatric Health 3[6], 543-549. 2009

Kirmani BF, Crisp ED, Kayani S, Rajab H. Role of intravenous levetiracetam in acute seizure management of children. Pediatric

Neurology 41[1], 37-39. 2009

Kirmani BF, Jacobowitz DM, Namboodiri MA. Developmental increase

of aspartoacylase in oligodendrocytes parallels CNS myelination. Brain Research.Developmental Brain Research 140[1], 105-115. 2003

Kirmani BF, Jacobowitz DM, Kallarakal AT, Namboodiri MA. Aspartoacylase is restricted primarily to myelin synthesizing cells in

the CNS: therapeutic implications for Canavan disease. Brain Research.Molecular Brain Research 107[2], 176-182. 2002

Batool F. Kirmani Letter to the Editor : The necessity for the future Education and debate Can doctors respond to patients' increasing

interest in complementary and alternative medicine? Commentary: Special study modules and complementary and alternative medicine—

the Glasgow experience BMJ 2001;322:154 2001

July 18, 2014 11


Reference List Abstract/Presentation

Batool F. Kirmani , William Hastings, Owais Khan, Edwin Crisp, and

Jose Aceves Should we consider Intravenous Levetiracetam an option for acute seizure management in children? European Federation of

Neurological Sciences Meeting , May 31-June 4, 2014 2014

Batool F. Kirmani and Diana H. Mungall Partial Seizures Misdiagnosed as Panic Attacks The First Annual Scott & White Research Days , May

8-9, 2013 The 166th Annual American Psychiatric Association

Meeting , May 18 - May 22, 2013, San Francisco , CA APA’s 65th Institute on Psychiatric Services Meeting, Philadelphia, PA October 10-

13, 2013 2013

Batool F. Kirmani and Diana H. Mungall Pseudoseizures in Patients With Chronic Epilepsy and Moderate Cognitive Impairment: The Need

for Video-EEG Monitoring for Adequate Diagnosis The 166th Annual

American Psychiatric Association Meeting , May 18 - May 22, 2013, San Francisco , CA APA’s 65th Institute on Psychiatric Services

Meeting, Philadelphia, PA October 10-13, 2013 2013

Batool F. Kirmani Significance of inpatient intensive seizure monitoring

for evaluation of atypical phenomena in chronic epilepsy patients with moderate cognitive impairment 30th International Epilepsy Congress,

Montreal, Canada June 25-27, 2013. 2013

Andrea Wenner, Jose Aceves, Diana Mungall, Richard Castillo and Batool F. Kirmani Efficacy and Tolerability of Vagal Nerve Stimulation

in Intractable pediatric epilepsy patients with brain anomalies The First

Annual Scott & White Research Days , May 8-9, 2013 2013

Andrea Wenner, Jose Aceves, Diana Mungall, Richard Castillo and Batool F. Kirmani Role of Vagal Nerve Stimulation in the Management

of Intractable Epilepsy in Children with Static Encephalopathy

American Neurological Association’s (ANA) 2013 Annual Meeting, New Orleans, LA October 13 – 15, 2013 2013

July 18, 2014 12



Owais A. Khan, Cheryl A. Cipriani, Chanin C. Wright, Edwin D. Crisp ,

Richard Castillo and Batool F. Kirmani Should we consider Intravenous Levetiracetam an option for Acute Seizure Management in Preterm

Neonates? The First Annual Scott & White Research Days , May 8-9, 2013 2013

William Hastings, Owais Khan, Edwin Crisp, Jose Aceves and Batool F.

Kirmani Efficacy and Tolerability of Intravenous Levetiracetam in

Children The 67th Annual American Epilepsy Society Meeting , December 6-10, 013 Washington DC. 2013

Batool F. Kirmani and Diana H. Mungall "Should we consider epilepsy

monitoring unit stay a gold standard to evaluate atypical events in chronic epilepsy patients?" 2012 Society for Neuroscience Annual

Meeting, New Orleans, LA. October 13-17, 2012. 2012

Batool F. Kirmani and Diana H. Mungall Importance of Intensive Video

EEG Monitoring In the Evaluation of Change in Seizure Semiology in Intractable Epilepsy Patients. The 66th Annual American Epilepsy

Society Meeting , November 30- December 4, 2012, San Diego, CA.

2012

Diana H. Mungall and Batool F. Kirmani Incidence of Seizures and Concomitant Pseudoseizures in the Epilepsy Monitoring Unit APA’s 64th

Institute on Psychiatric Services Meeting, New York City, NY October 4-7, 2012. 2012

Jennifer L. Robinson, Ryan Rister, Brandon Bohannon, Austin Clark, Daniel Barron, Peter Fox, and Batool Kirmani Spontaneous blood

oxygen level dependent signal (BOLD) differences in temporal lobe (TLE) and idiopathic generalized epilepsy (IGE) The 66th Annual

American Epilepsy Society Meeting , November 30- December 4, 2012,

San Diego, CA 2012

July 18, 2014 13



Owais A. Khan, Cheryl A. Cipriani, Chanin C. Wright, Edwin D. Crisp

and Batool F. Kirmani, Role of Intravenous levetiracetam in Acute Seizure Management in Preterm Neonates. The 66th Annual American

Epilepsy Society Meeting , November 30- December 4, 2012, San Diego, CA. 2012

Owais A. Khan, Esther Y. Chang, Cheryl A. Cipriani, Chanin C. Wright,

Edwin D. Crisp and Batool F. Kirmani, Experience with Intravenous

Levetiracetam in Preterm Neonates. The 63rd Annual Meeting of the American Academy of Neurology, April 9- April 16 , 2011, Honolulu,

Hawaii. 2011

Owais A. Khan, Esther Y. Chang, Cheryl A. Cipriani, Chanin C. Wright, Edwin D. Crisp and Batool F. Kirmani, Role of Intravenous

Levetiracetam in acute seizure management in term and preterm

infants. International Symposium on Neonatal Seizures, Tokyo, April 8-10, 2011 2011

Prasanth S. Ariyannur , Rachel Riberio, John R. Moffett , Batool F.

Kirmani , M. A. Aryan Namboodiri and Yumin Zhang. Tryptophan

Metabolites as Immune Regulators: Studies on Effectiveness in Experimental Autoimmune Encephalomyelitis. The 63rd Annual

Meeting of the American Academy of Neurology, April 9- April 16 ,2011, Honolulu, Hawaii. 2011


Kirmani , M. A. Aryan Namboodiri and Yumin Zhang. Tryptophan

Metabolites as Immune Regulators in Experimental Autoimmune Encephalomyelitis. 2011 Society for Neuroscience Annual Meeting,

November 12-16, 2011, Washington DC 2011

Taylor B. Fox and Batool F. Kirmani A Complicated Case of Epilepsy

with New Onset Concurrent Pseudoseizures : A Diagnostic Dilemma IMPACT 2011 Conference- AAPA’S 39TH Annual Conference, May 30-

June 30, 2011, Las Vegas, NV. 2011

July 18, 2014 14



Ariyannur PS, Moffet JR, Kirmani BF, Namboodiri MAA, Jacobowitz DM.

Differential Expression of Acetyl Co A Synthetases: metabolic implications of ketogenic diet. Presentation at the NIH Research

Festival, October 5-8, Bethesda, MD. 2010

Namboodiri MAA, Moffett JR, Ariyannur PS, Arun P, Madhavarao CN, Kirmani BF. Differential cellular distribution of acetyl CoZ synthetases

in the rat brain: implications for ketogenic diet mediated

neuroprotection. Presented at the 62nd Annual Meeting of the American Academy of Neurology, in Toronto, Ontario, April 10-

17. 2010

Nasdady A, Kirmani BF. Source localization of seizure foci from eeg. Presentation at the64th Annual American Epilepsy Society Meeting,

December 3-7, San Antonio, TX. Epilepsia 0 Suppl. 0 (Abst.

2.163). 2010

Robinson J, Kirmani BF, Barron D, Savjani R, Malla R, Fox P. Meta-analytic connectivity modeling of mesial temporal lobe epilepsy.

Presented at the 64th Annual American Epilepsy Society Meeting,

December 307, San Antoino, TX. Epilepsia 0 Suppl. 0 (Abst. 3.203). 2010

Robinson JL, Kirmani BF, Sanghera M, Phillips-Sabol J, Cruz D, Wright

CJ, Friehs G. Functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI): an efficient, non-invasive alternative to

conventional pre-surgical planning in neurosurgery. Presented at the

7th Annual World Congress for Brain Mapping and Image Guided Therapy, in Bethesda, M.D., May 24-27. 2010

Robinson JL, Kirmani BF, Sanghera M, Phillips-Sabol J, Cruz D, Wright

CJ, Friehs G. Functional magnetic resonance imaging (fMRI) and

diffusion tensor imaging (DTI): an efficient, non-invasive alternative to conventional pre-surgical planning in neurosurgery. Presented at the

National HMO Research Network Conference, in Austin, TX, March 21-24. 2010

July 18, 2014 15



Jones G, Crisp ED, Kirmani BF. Efficacy and tolerability of Keppra XR.

Presentation at the 63rd Annual American Epilepsy Society Meeting, December 4-8, Boston, MA. Epilepsia 0 Suppl. 0 (Abst. 2.200). 2009

Moffett JR, Ariyannur PS, Arun P, Madhavarao C, Namboodiri MAA,

Kirmani BF. Immunohistochemical localization of mitochondrial acetyl CoA synthetase in the adult rat brain. Presented at the Society for

Neuroscience 39th Annual Meeting, October 17-21, Chicago, IL. 2009

Kayani S, Crisp ED, Kirmani BF. Role of intravenous levetiracetum in

acute exacerbation of seizures and status epilepticus in pediatric population. The 62nd Annual American Epilepsy Society Meeting,

December 5-9, Seattle, WA. Epilepsia (Abst. 2.105) 2008

DeLorenzo RJ, Kirmani BF, Jakkampudi V, Towne AR, Isaacs J, Choi S,

Garnett L, Ramakrisnan R. A prospective study of adult status epilepticus in a community hospital setting. Resident Research Day,

Medical College of Virginia, June 1, 2006 and AAN 59th Annual meeting (submitted as a post). The 59th Annual Meeting of the

American Academy of Neurology, April 28-May 5, Boston, Mass. 2007

Kirmani BF, Ess KC. Levetiracetum and status epilepticus in tuberous

sclerosis complex. The 61st Annual American Epilepsy Society Meeting, November 30-December 4, Philadelphia, PA. Epilepsia (Abst.

1.180), 2007

Kirmani BF, Jakkampudi V, Towne AR, Isaacs J, Choi S, Garnet L,

Ramakrisnan R, DeLorenzo RJ. A prospective study of adult status epilepticus in a community hospital setting. 2006. The 59th Annual

Meeting of the American Academy of Neurology, April 28-May 5, 2007, Boston, Mass. The Resident Research Day, June 1, 2006, Medical

College of Virginia, Richmond, VA. 2007

July 18, 2014 16



Kirmani BF, Jacobowitz DM, Namboodiri MAA. Role of aspartoacyclase

during myelination: implications in canavan disease. First International Symposium on N-Acetyl Aspartoacyclase, September 13-14, NIH,

Bethesda, MD. 2004

Kirmani BF, Jacobowitz DM, Namboodiri MAA. Cellular localization of aspartoacylase in the developing brain. Uniformed Services University

Faculty Senate Research Day 2002 and Ninth Graduate Student

Colloquium, May 15-16, Bethesda, MD. 2002

Kirmani BF, Jacobowitz DM, Namboodiri MAA. Localization of aspartoacylase in the large neural tracts of the developing brain.

Society for Neuroscience 32nd Annual Meeting, November 2-7, Orlando, Florida. 2002

Kirmani BF, Jacobowitz DM, Abraham TK, Namboodiri MAA. Aspartoacylase is limited to myelin synthesizing cells of the CNS:

therapeutic implications for canavan disease. NIH Research Festival 2001, October 2-5, Bethesda, MD. NIH Research Festival Poster No.

NB-17 and at 2001 Eleventh Annual USUHS Neuroscience Program,

November 28, Bethesda, MD. Abstract No: 15. 2001

Presentation/Abstract

Owais A. Khan, Esther Y. Chang, Cheryl A. Cipriani, Chanin C. Wright,

Edwin D. Crisp and Batool F. Kirmani, Experience with Intravenous Levetiracetam in Preterm Neonates. The 63rd Annual Meeting of the

American Academy of Neurology, April 9- April 16 , 2011, Honolulu, Hawaii. 2011

Owais A. Khan, Esther Y. Chang, Cheryl A. Cipriani, Chanin C. Wright, Edwin D. Crisp and Batool F. Kirmani, Role of Intravenous

Levetiracetam in acute seizure management in term and preterm infants. International Symposium on Neonatal Seizures, Tokyo, April

8-10, 2011 2011

July 18, 2014 17


Reference List Presentation/Abstract


Kirmani , M. A. Aryan Namboodiri and Yumin Zhang. Tryptophan Metabolites as Immune Regulators: Studies on Effectiveness in

Experimental Autoimmune Encephalomyelitis. The 63rd Annual Meeting of the American Academy of Neurology, April 9- April

16 ,2011, Honolulu, Hawaii. 2011

Taylor B. Fox and Batool F. Kirmani A Complicated Case of Epilepsy

with New Onset Concurrent Pseudoseizures : A Diagnostic Dilemma IMPACT 2011 Conference- AAPA445S 39TH Annual Conference, May

30- June 30, 2011 , Las Vegas, NV. 2011

Clinical Research

An Open-Label study to Evaluate the Safety, Efficacy and

Pharmacokinetics of SAGE-547 Injection as Adjunctive Therapy in the Treatment of Adults with Super-Refractory Status Epilepticus, Protocol

547-SSE-201 Site approved Role on grant : Principal Investigator (PI) 2014

Double-blind, Placebo-controlled parallel-group multicenter study of the efficacy and safety of pregabalin as adjunctive therapy in children

1 month through < 4 years of age with partial onset seizures Site approved Role on grant : Principal Investigator (PI) Funding Agency:

Pfizer , Inc. 2014

Double-blind, Placebo-controlled parallel-group multicenter study of

the efficacy and safety of pregabalin as adjunctive therapy in children 4-16 years of age with partial onset seizures Site approved Role on

grant : Principal Investigator (PI) Funding Agency: Pfizer , Inc. 2014

Pharmacokinetic study in lactating women who are taking pregabalin

Role on grant : Principal Investigator (PI) Site approved Funding Agency: Pfizer , Inc. 2014

July 18, 2014 18


Reference List Clinical Research

Randomized, Double-Blind, Placebo Controlled Trial Examining the

Safety and Efficacy of Midazolam Intranasal Spray (USL261) for the Treatment of Intermittent Bouts of Increased Seizure Activity in the

Epilepsy Monitoring Unit (EMU) Role on grant : Principal Investigator (PI) Grant Period: 2014 -Present Funding Agency: Upsher-Smith

Laboratories, Inc. 2014

A Randomized , Double-blind, Placebo controlled, Parallel group,

multicenter trial of pregabalin as adjunctive therapy in pediatric and adult subjects with primary pregabalin as adjunctive therapy in

pediatric and adult subjects with primary generalized seizures- PROTOCOL A0081105 Role on grant : Principal Investigator (PI) Grant

Period: 2013-Present Funding Agency: Pfizer, Inc. 2013

A0081106: A Randomized , Double-blind, Placebo controlled, Parallel

group, multicenter trial of pregabalin as adjunctive therapy in pediatric and adult subjects with primary generalized tonic-clonic seizures Role

on grant : Principal Investigator (PI) Grant Period: 2013- Present Funding Agency: Pfizer , Inc. 2013

A Double-blind, Randomized, Placebo-controlled, Multicenter, Parallel-group Study with an Open-label Extension Phase to Evaluate the

Efficacy and Safety of Adjunctive Perampanel in Primary Generalized Tonic-Clonic Seizures (Protocol E2007-G000-332) Role on grant :

Principal Investigator (PI) Grant Period: 2012-Present Funding Agency: Eisai Medical Research , Inc. 2012

A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multi-center Trial of Pregabalin Controlled Release Formulation as Adjunctive

Therapy in Adults with Partial Onset Seizures - Protocol A0081194 Role on grant : Principal Investigator (PI) Grant Period: 2011- 2012

Funding Agency: Pfizer, Inc. 2012

A Randomized, Multicenter, Double-blind, Placebo-Controlled, Parallel-

Group, Phase 3 Study to Evaluate the Efficacy and Safety of USL255 as Adjunctive Therapy in Patients with Refractory Partial-Onset Seizures

(Protocol #P09-004) Role on grant : Principal Investigator (PI) Grant Period: 2011-2012 Funding Agency: USL , Inc. 2012

July 18, 2014 19



Open-Label Extension Study to Evaluate the Safety of USL255 as

Adjunctive Therapy in Patients with Refractory Partial-Onset Seizures who had Participated in P09-004, a Randomized, Multicenter, Double-

Blind, Placebo-Controlled, Parallel-Group, Phase 3 Study (Protocol #P09-005) Role on grant : Principal Investigator (PI) Grant Period:

2011-2012 2012

A double-blind, Historical Control Study of the Safety and Efficacy of

Eslicarbazepine Acetate Monotherapy in Subjects with Partial Epilepsy Unresponsive to Current Antiepileptic Drugs (Protocol No . 093-045 )

222 Sepracor , Inc. (2009- Present). 2009

Long-Term Eslicarbazepine Acetate Extension Study in Subjects with Partial Epilepsy Unresponsive to Current Antiepileptic Drugs ( Protocol

No . 093-050 ) 222 Sepracor , Inc. (2009- Present). 2009

Multicenter, Open-Label Extension Study to Evaluate the Long-Term

Safety and Tolerability of Oxcarbazepine Extended-Release (OXC XR) as Adjunctive Therapy in Subjects with Refractory Partial Epilepsy on

up to Two Concomitant Antiepileptic Medications. (2009-

Present). 2009

Multicenter, Double-Blind, Randomized, Placebo-Controlled, Three-Arm, Parallel Group Study to Evaluate the Efficacy and Safety of

Oxcarbazepine Extended Release (OXC XR) (1200 and 2400mg/day) as Adjunctive Therapy in Subjects with Refractory Partial Seizures due

to Epilepsy on up to Two Concomitant AntiepilepticMedications

(Protocol 804P301). (2009-Present). 2009

A Historical-controlled, Multicenter, Double-blind, Randomized Trial to Assess the Efficacy and Safety of Conversion to Lacosamide

400mg/day Monotherapy in Subjects with Partial-onset Seizures 762

(Protocol SP902)- Schwarz Pharma, Inc. (2008- 2010). 2008

July 18, 2014 20



A double-blind, randomized, historical-controlled, multicenter efficacy

and safety study of Pregabalin (Lyrica) as monotherapy in patients with refractory partial seizures (Protocol A0081047)- Pfizer, Inc.

(2008- Present) 2008

A Multicenter, Open-label Extension Trial to Assess the Long-term Use of Lacosamide Monotherapy and Safety of Lacosamide Monotherapy

and Adjunctive Therapy in Subjects with Partial-onset Seizures

(Protocol SP902)- Schwarz Pharma, Inc. (2008- 2010). 2008

An Open-Label Multicenter Extension Study to Determine Long Term Safety and Efficacy of Pregabalin (Lyrica) as Monotherapy in Patients

with Partial Seizures -Pfizer, Inc. (2008-Present) 2008

Lamotrigine Extended-Release in Elderly Patients with Epilepsy- Glaxo

Smith-Kline Inc.(2008-2010) 2008

July 18, 2014 21

Documents

Batool F. Kirmani, MD Reference Listscottandwhite.photobooks.com/PhysicianPDFs/Research/PHY000148.pdfBatool Kirmani ,Diana Mungall, ... Owais Khan, Amanda Williams, Ekokobe Fonkem,