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Cutting Edge Technology made Simple
Basic CT Physics
Cutting Edge Technology made Simple
Basic CT Physics
•Conventional X-Rays– Single projection image superimposed tissues
•Computerized Tomography – Axial image obtained from hundreds
of projections
Std. Resolution: 500 - 1200 projections
High Resolution: 900 - 2400 projections
– Tissue superposition only within one slice thickness
Cutting Edge Technology made Simple
Basic CT Physics
•Measured physical entity: tissue density
•Information provided: organ structure
•CT density unit: 1 Hounsfield Unit (HU) = 0.1% density of
water Air (zero density) = -1000 HU; Water = 0 HU
•Precision & validity of CT densities:– Relative only; CT uses a polychromatic X-ray beam – CT densities are voltage, object size & real density
dependent– Precise density measurements in CT require dedicated calibrations
Cutting Edge Technology made Simple
CT Spectrum of densities
HU
Cutting Edge Technology made Simple
Fan & Cone Beam Angles
Cutting Edge Technology made Simple
2D Fan Beam Rebinning
Cutting Edge Technology made Simple
CT Image Reconstruction
•2D Fan Beam Image Reconstruction (1970 – 2001) – Filtered back-projection into a 2D
matrix (Pixels) assuming parallel X-ray beams & ignoring the Cone Angle
• COBRA (COne Beam Reconstruction
Algorithm) (>2001)– Filtered back-projection into a 3D
matrix (Voxels)– Each Voxel reconstructed individually.– Only views passing through each
individual voxel during the acquisition process are back-projected into it
Cutting Edge Technology made Simple
Computer Simulation(16 x 1.5mm)
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4 mm from mid -plane
8 mm from mid -plane
Cone Beam ReconFan Beam Recon
COCOnene B Beameam RReconstructioneconstruction AAlgorithm - lgorithm - COBRACOBRA
Cutting Edge Technology made Simple
2D back-projection 3D back-projection2D back-projection 3D back-projection
COCOnene B Beameam RReconstructioneconstruction AAlgorithm - lgorithm - COBRACOBRA
Cutting Edge Technology made Simple
64 channel
1.4 pitch
128 channel
simulation
1.4 pitch
2D Fan Beam
Philips 3D COBRA
COCOnene B Beameam RReconstructioneconstruction AAlgorithm - lgorithm - COBRACOBRA
Cutting Edge Technology made Simple
CT - Image Quality
•Purpose of CT: Image guided radiographic diagnosis
•Image Quality determines diagnostic capability•Image Quality parameters:
– Low Contrast Resolution: The ability to discriminate between tissues of similar densities. Image noise plays a limiting role – High Contrast Spatial Resolution: The smallest (high contrast) object which can be recognized in
an image. Spatial resolution is determined by the basic scanner
design
– Temporal Resolution: The smallest time difference to observe two events
Cutting Edge Technology made Simple
Low Contrast Resolution
Cutting Edge Technology made Simple
Factors Determining Low Contrast Resolution•Detection System: type, design & efficiency
•X-ray beam filtration: optimal design for beam hardness
•Scan Voltage: lower voltage provides improved low contrast resolution
•Signal-to-Noise Ratio: – Proportional to Dose (mAs)
– Improved when post-collimation is available, protecting the detectors from scattered
radiation
Cutting Edge Technology made Simple
Mx8000: Low Contrast Resolution Scan
Phantom details Axial Scan
0.3%
1% Contrast or 10 HU
0.5%
Cutting Edge Technology made Simple
High Contrast Spatial Resolution
•It is recommended to measure spatial resolution in terms of spatial frequencies [lp/cm]
•The relation between spatial coordinates [mm] and spatial
frequencies [lp/cm] is:
Object [mm] = 10 / (2*[lp/cm])
For example: a cutoff spatial frequency of 20 lp/cm corresponds to a spatial resolution of 0.25 mm
Cutting Edge Technology made Simple
Factors Determining Spatial Resolution
•Design Parameters:– Detector aperture width (Aeff) at isocenter– Focal spot size (s)– Sampling density (< Aeff/2)
•Reconstruction Algorithm:– Filter Modulation Transfer Function
•Display Parameters:– Pixel size: p = FOV/(Matrix * Zoom)– Good Imaging Practice: p < image spatial
resolution
Cutting Edge Technology made Simple
Spatial Resolution: Sampling Rate
•Nyquist Theorem “Aliasing” artifacts suppression in the image of an object which has a maximum frequency N (Nyquist frequency), requires a sampling frequency of AT LEAST 2xN
•Nyquist frequency of a CT scannerN = 1 / Aeff
•Conclusion: Successful suppression of “aliasing” artifacts requires a sampling rate of AT LEAST 2/Aeff, or
Two Samples per Effective Detector Aperture WidthTwo Samples per Effective Detector Aperture Width
Cutting Edge Technology made Simple
Spatial Resolution in 3rd Generation
Scanners“Aliasing” Suppression: Quarter Detector Offset between
center of rotation and
central detector line providing
2 “interleaved” [0o & 180o ] samples
per effective detector aperture, displaced by one-half detector
width
Cutting Edge Technology made Simple
3rd Generation Scanners: Quarter Detector Offset
“Aliasing” Artifacts Suppression: 2 samples per detector width
Cutting Edge Technology made Simple
Commercial High Contrast Spatial Resolution Phantom (up to 20 lp/cm)
20 lp/cm
18 lp/cm
Cutting Edge Technology made Simple
Proprietary High Contrast Resolution Phantom (15 cm f & up to 25 lp/cm)
Cutting Edge Technology made Simple
Mx8000 – Spatial Resolution
23lp/cm @ 3% MTF 24 lp/cm @ 2% MTF
Cutting Edge Technology made Simple
CT - Image Quality Low Contrast versus High Contrast Resolution
Rule of thumb: Increase in Spatial Resolution Decrease in Low Contrast Resolution
Smooth Filter Sharp Filter
Cutting Edge Technology made Simple
Nominal Slice Width
• The Nominal Slice Width is The Nominal Slice Width is the the convolution of the detectorconvolution of the detector aperture in the Z-axis and the aperture in the Z-axis and the focalfocal spot in the Z-axisspot in the Z-axis
• The result depends on the The result depends on the realreal respective distributions:respective distributions:
– The detector can be very The detector can be very well represented by a uniform well represented by a uniform distributiondistribution– The Focal Spot distribution The Focal Spot distribution
is more complex since it is in is more complex since it is in between a gaussian and a between a gaussian and a uniform distributionuniform distribution
Cutting Edge Technology made Simple
Mathematical Convolution
Convolution of Gaussian Distributions
Gaussian
w/ STD
Gaussian
w/ STD
Gaussian
w/ STD
= 2 + 2
=
a - b
a + b
a
a b
Convolution of Uniform Distributions
Cutting Edge Technology made Simple
DFSTM X-Ray Tube Design
Dynamic deflection of Dynamic Focal Spot Design
cathode electron beam,back and forth, creating2 focal spot positionson the same anodetrack and at a fixeddistance between them,so that the distance between two samplesat the isocenter is exactlyone-half detector width
Cutting Edge Technology made Simple
DFSTM X-Ray Tube Design
DFS Tube Conventional Tube
Dynamic Focal Spot
X-ray Tube Design
Doubles
Ray Density and thus
Doubles
Spatial Resolution with the same number of detectors
Cutting Edge Technology made Simple
Scan with Dynamic Focal Spot feature
Without With
Cutting Edge Technology made Simple
Without With
Scan with Dynamic Focal Spot feature
Cutting Edge Technology made Simple
Patient Dose Path
Cutting Edge Technology made Simple
CT Artefacts
The problem How it looks like
Unconsistent data (partial volume) Streaks
Polychromatic X-ray beam Bands
Sampling (Nyqusit theorem) Aliasing
Cone Beam Hyper/hypo dense streaks at density gradients
High density tissues/objects Blooming (apparent size)
Cutting Edge Technology made Simple
Streaks, Polychromatic & Cone Beam Streaks, Polychromatic & Cone Beam artefacts…artefacts…
Cutting Edge Technology made Simple
Blooming Artefact: density
White
Dark
WwWc
Apparent size
Cutting Edge Technology made Simple
Wc
1
Reduce apparent size: increase window center
Wc
2
Blooming Artefact: density
Cutting Edge Technology made Simple
UncompromizedSpiral Scanning
Cutting Edge Technology made Simple
Spiral (Helical) Scanning
Continuous data acquisition during gantry rotation and patient table displacement at constant speed
Cutting Edge Technology made Simple
Spiral Scanning Benefits
• Volumetric Volumetric data acquisitiondata acquisition
• SingleSingle breath-holdbreath-hold acquisitionacquisition – No lesion misregistration No lesion misregistration – 94% of patients can hold their94% of patients can hold their breath forbreath for 30 sec30 sec
• Good control of delayGood control of delay between injection and scan:between injection and scan:– Study performed within a desired blood phaseStudy performed within a desired blood phase– Multi-phase studies can be performed with back-to-back Multi-phase studies can be performed with back-to-back
spiral acquisitionsspiral acquisitions
• Efficient use of contrast materialEfficient use of contrast material
Cutting Edge Technology made Simple
Common Compromises in Single-Slice CT
Image QualityImage Quality OROR Organ CoverageOrgan Coverage
Pitch Pitch 1 1 Pitch Pitch 1 1
Cutting Edge Technology made Simple
The Solution: Multi-Slice CT
Cutting Edge Technology made Simple
Multi-Slice CT: No Need to Compromise
Pitch Pitch Q1 Q1 Pitch Pitch Q1 Q1
Image QualityImage Quality ANDAND Organ CoverageOrgan Coverage
Cutting Edge Technology made Simple
Multi-Slice RSVP Advantages
Cutting Edge Technology made Simple
Multi-Slice RSVP Advantages
Cutting Edge Technology made Simple
Multi-Slice Resolution Advantage Quad-Slice Dual-Slice Single-Slice
4x2.5mm; 2.5cm/sec 2x5.0mm; 2.5cm/sec 10mm; 2.5cm/sec72 cm coverage; 28 sec; 120kV / 130 mAs
Cutting Edge Technology made Simple
72 cm coverage 36 cm coverage 18 cm coverage 3.2 mm Eff. ST; 28 sec; 120kV / 130mAs
Multi-Slice Volume Advantage Quad-Slice Dual-Slice Single-Slice
Cutting Edge Technology made Simple
Spiral Scanning: Basic Concepts
Pitch (P)
Table displacement during one full (3600) gantry rotation
Beam collimation
Example: Pitch 1:1 (P=1) means that the table advances by exactly one beam collimation during one full gantry rotation
Cutting Edge Technology made Simple
Coverage (V)
V = (n x P / RT) x NST x T = SAR x NST x T where: n x P / RT = Slice Acquisition Rate (SAR) [slices / sec] n slices acquired during one gantry rotation of RT sec @ pitch P NST = Nominal Slice Thickness; C = n x NST = Collimation T = Acquisition Time; P = Pitch (when applicable)
Spiral Scanning: Basic Concepts
Cutting Edge Technology made Simple
Spiral Scanning: Basic Concepts
Image
Reconstruction
• The bed position of the image and the reconstruction increment
are at user’s choice, within the acquired volume
• The actual raw data for an image reconstruction, at a given position, is obtained by interpolating data points from successive
gantry rotations
Cutting Edge Technology made Simple
Spiral Scanning: Image Reconstruction