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No To Hattatsu.1991 Nov;23(6):583-9.

Clinicoencephalographic study of periodic

lateralized epileptiform discharges ininfants].

[Article in Japanese]

Kawashima K,Hamano K,Iwasaki N,Takeya T,Horigome Y.

Source

Institute o !pecial "#ucation, $ni%ersity o Tsuku&a, I&araki.

Abstract

The mechanism o perio#ic laterali'e# epileptiorm #ischarges ()*"+s still remains unclear,

although it has &een the su&-ect o a num&er o theories. e in%estigate# the relationship

&etween the le%el consciousness an# )*"+s in or#er to clariy &oth the clinical signiicance

an# the mechanism o )*"+s. e stu#ie# two neonates an# two inants with acute organic

lesions o the &rain (cere&ral inarction, meningoencephalitis, cere&ral hemorrhage, acute

inantile hemiplegia, o whom all showing )*"+s in ""/. In each case, we analy'e#

se0uential ""/ recor#s an# the le%el o consciousness, an# measure# the perio#icity, %oltage

an# #uration o )*"+s &y a computer controlle# #igiti'er. In each case, the perio#icity an#

%oltage o the #ischarges were relate# to the le%el o consciousness. The appearance rate o)*"+s was relati%ely high at the le%el o consciousness rom III1233 to III1433. The in%erse

correlation &etween the re0uency (25perio#icity an# the %oltage o )*"+s was signiicant in

678 o the total recor#s o )*"+s9 it was also re0uently o&ser%e# at the le%el o

consciousness &etween III1233 an# III1433. :rom a&o%e in#ings we conclu#e# that an

appropriate #egree o #amage to pro#uce )*"+s is re0uire# in &oth the cere&ral corte; an#

su&cortical white matter correspon#ing to the le%el o consciousness rom III1233 to III1433.

)?3436

[)u&


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+i%ision o Neurology, +epartment o


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pre#ominantly motor, #ysphasia. In complementary tests, the most noteworthy eatures were

positi%e luetic serology in the &loo# an# in cere&rospinal lui# (D!:, which was conirme#

&y means o treponemic assays. The patient was treate# with penicillin or two weeks. The

stu#y was complete# with a magnetic resonance (


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were #etecte# in 6 patients in this stu#y. Acute structural lesions in%ol%ing cortical gray

matter with a#-acent su&cortical white matter were oun# in most o the patients with )*"+s,

&ut the lesion locali'ation an# age, acute or chronic, %arie#.

2@@7 @1G7.

Defining the role of structural lesions and

metabolic abnormalities in periodic

lateralized epileptiform discharges.

aro0ue H/ Jr, /on'ales )D, Jha%eri H!, *eroy :,Allen "D.

Source

+epartment o Neurology, $ni%ersity o Te;as !outhwestern 64761

GG@>.

Abstract

e re%iewe# the ""/, clinical maniestations, compute# tomography (DT an# magnetic

resonance imaging (


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Abstract

PURPOSE:

e assesse# neuroimaging lesion type an# #istri&ution in patients with perio#ic laterali'e#

epileptiorm #ischarges ()*"+s, with a %iew to i#entiying electrographic #ierences&etween )*"+s associate# with #iering lesion locations. ur o&ser%ations le# us to

consi#er a conceptual synthesis &etween )*"+s an# perio#ic comple;es ()Ds.

METHODS:

etrospecti%e re%iew o acute neuroimaging results (DT5


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inter%al #iuse #ischarges. e also #iscuss morphology, etiologies, an# clinical correlates o

each pattern an# possi&le pathophysiological mechanisms o perio#icity.

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