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Vincenzo Foppa, 1462 “The miracle of the salvaged foot” Cappella Portinari, S. Eustorgio Church Milan, Italy BAD (Big Artery Disease) and SAD (Small Artery Disease) – an appraisal of the challenges in CLI revascularization

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Page 1: BAD (Big Artery Disease) and SAD (Small Artery Disease) an

Vincenzo Foppa, 1462“The miracle of the salvaged foot” Cappella Portinari, S. Eustorgio Church Milan, Italy

BAD (Big Artery Disease) and SAD (Small Artery Disease) – an appraisal of the challenges in CLI revascularization

Page 2: BAD (Big Artery Disease) and SAD (Small Artery Disease) an

Disclosure

Roberto Ferraresi, MD

In the last 2 years I have the following potential conflicts of interest to report:

Consultant: Medtronic, Abbott, Boston Scientific, Contract Medical International, Cook, Asahi, Ivascular, Biotronik, Limflow, Spectranetics, Shire, Kardia, Astra Zeneca, Orbus, Bard, Philips, Volcano, Novena, Angiodroid, M&L Healthcare

Virtual shareholder: Limflow

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Baseline → 2017 Feb

- 8 yo→ T1DM

- 42 yo→ blindness

- 44 yo→ ESRD-HD

- 45 yo→ AMI (PCI)

- 48 yo→ CLTI onset: pain at rest,

suffering of the 1-2 toes

- Poor socio-economical status

2017 2018 2019

J F M A M J J A S O N D J F M A M J J A S O N D J F M

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+ 4 months

- Persistent pain at rest

- Suffering of 1-2 toes, 1 falanx

osteomyelitis

2017 2018 2019

J F M A M J J A S O N D J F M A M J J A S O N D J F M

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1 wound

3 angio

2 plain X-ray

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+ 4 months

• No pain• Complete healing

2017 2018 2019

J F M A M J J A S O N D J F M A M J J A S O N D J F M

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2017 2018 2019

J F M A M J J A S O N D J F M A M J J A S O N D J F M

+ 6 months

• Pain during dialysis• New infected ulcer

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2017 2018 2019

J F M A M J J A S O N D J F M A M J J A S O N D J F M

+ 7 months

• Increasing pain at rest• Suffering of 1-2-3 toes

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Jun 2017 April 2018 2018 Nov

2017 2018 2019

J F M A M J J A S O N D J F M A M J J A S O N D J F M

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+22 months → Dec 2018

pDVA

2017 2018 2019

J F M A M J J A S O N D J F M A M J J A S O N D J F M

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pDVA acute result

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+1 months

- Pain at rest +++

- Suffering of all toes,

reinfection, antibiotics

- TcPO2 5 mmHg

2017 2018 2019

J F M A M J J A S O N D J F M A M J J A S O N D J F M

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Arterialized circuit focalization

to the forefoot

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+30 days

- Dorsal necrosis

- Good plantar

aspect

- New angio

- TMT amputation

2017 2018 2019

J F M A M J J A S O N D J F M A M J J A S O N D J F M

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Jun 2017 April 2018 2018 Nov

2017 2018 2019

J F M A M J J A S O N D J F M A M J J A S O N D J F M

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Jun 2017

2017 2018 2019

J F M A M J J A S O N D J F M A M J J A S O N D J F M

2018 Feb

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+20 days

- Dorsal necrosis

- Good plantar

aspect

2017 2018 2019

J F M A M J J A S O N D J F M A M J J A S O N D J F M

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+35 days

- New infection

- WBC 16.000

- Pain +++

2017 2018 2019

J F M A M J J A S O N D J F M A M J J A S O N D J F M

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+40 days

- BTK major amputation

2017 2018 2019

J F M A M J J A S O N D J F M A M J J A S O N D J F M

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• SAD, the progressive desertification of the distribution system of the foot, is a major determinant of CLTI

• PTA in foot vessels has always a transient result

• Infection is one of the major determinant of major amputation

• FVA procedures are still in an “artisanal” era

• Was this complex approach correct for a pt coming from a distant region and lacking of a strong socio-economical (and medical) support?

• Do you think that a primary major amputation would have been the best choice?

• The target was independence: he wants to walk at home and to go to the toilet by himself! Nothing more….

Fighting CLTI we fight for dignity!

Page 39: BAD (Big Artery Disease) and SAD (Small Artery Disease) an

Vincenzo Foppa, 1462“The miracle of the salvaged foot” Cappella Portinari, S. Eustorgio Church Milan, Italy

BAD (Big Artery Disease) and SAD (Small Artery Disease) – an appraisal of the challenges in CLI revascularization