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B cells. Humoral immune response. Antigen receptors on lymphocytes. B cell. T cell. Antigens : protein s , polysaccharides , lipid s , nucleic acids, small molecules Conformational and linear epitops. Complex of peptid e -MHC molecule on an AP C Linear epitop s. B cell maturation. - PowerPoint PPT Presentation
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Antigen receptors on lymphocytes
Antigens: proteins, polysaccharides, lipids, nucleic acids, small molecules
Conformational and linear epitops
Complex of peptide-MHC molecule on an APC
Linear epitops
B cell T cell
Active Btk enables:
survival, proliferation and further maturation etc.
Mutation of BTK gene:
X-linked agammaglobulinemia
(Bruton’s agammaglobulinemia)
Btk
(Bruton’s tyrosine kinase)