Asia’s Premier Partnering Event for the Biotechnology Industry

Copyright© ICS Convention Design, Inc., All rights reserved.

BioJapan Team

ICS Convention Design, Inc.

February 2014

Asia’s Premier Partnering Event for the Biotechnology Industry


About BioJapan

BioJapan provides you an opportunity to meet with 700+ biotech and life science companies in Yokohama. Business development teams from almost all global and Japanese pharma companies will gather in Yokohama for the 16th BioJapan. The 2014 event will consist of Partnering, Exhibition and Seminars.

Synergy

Exhibition Seminars

Partnering

Overview

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Event Outline

Japan Pharmaceutical Manufacturers Association

Japan Bioindustry Association

BioJapan 2014 -World Business Forum-

Date: October 15 (Wed.)- 17 (Fri.), 2014

Venue: Pacifico YOKOHAMA *YOKOHAMA is a port city just 30 minutes away from the center of Tokyo

Organizer: BioJapan Organizing Committee, ICS Convention Design, Inc.

Overview

http://www.jpma.or.jp/english/

http://www.jba.or.jp/pc/en/


Keynote Speech Organizer’s Seminars Luncheon Seminars Sponsored Seminars

BioJapan 2014 Floor Layout *Subject to change

Annex Hall Exhibition Hall *Partnering Area, Exhibition and Seminars /13,000 spm

40 Sessions in Total with 5,000+ audiences!

Exhibitor’s Presentations Academic Seeds Presentations

100+ Sessions on Up-to-date Seeds!

Global Partnering Seminar

Pacifico Yokohama

*Seminars

Overview

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Keynote Speech Three speakers on pharmaceutical, food, industrial biotechnology or policy

(1) Environment and Energy "Green Innovation Summit" Biofuel or Bio-refineries

(2) Medicine, Pharmaceuticals and Healthcare "Life Innovation Summit" Visions and Strategies for the Future by Global Pharmas iPS Cell Research Update Personalized medicine Medical devices Mobile Health

(3) Food, Agriculture and Fishery Industries "Functional Food Summit" New breeding technologies or artificial environment control

(4) Foundation of Biotechnology-based Industry "Cluster Summit" The key to succeed bio-ventures

Organizer’s Seminars Program *Subject to change Topics

Academic seminars held daily will provide the most up- to-date information on the latest technology.

40 sessions in total with 5,000+ audiences!


BioJapan 2013 Highlights

Partnering：･ 607 companies / 1,054 delegates from 27 countries ･ 4,480 meetings Exhibition：･ 479 exhibitors / 386 booth stands from 21 countries ･ 12,487 visitors Seminars: ･ 19 Organizer's seminars ･ 14 Sponsored seminars ･ 155 Company presentations

Overview

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1600

3372

4,747

1000

2000

3000

4000

5000

BioJapan Growth 2011 - 2013 Overview

Number of Meetings

Number of Exhibitors

327

434 479

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100

200

300

400

500

600


Japanese Pharma

Partnering Participating Companies at BioJapan 2013

*Almost all Japanese pharma companies participated in 2013.

Bio Cluster in Japan

*Approx. 150 Japanese biotech companies participated in 2013.

Ajinomoto, Asahi Kasei Pharma, Astellas, Chugai Pharmaceutical, Daiichi-Sankyo, Dainippon Sumitomo Pharma, Eisai, Hisamitsu Pharmaceutical, Kaken Pharmaceutical, Kissei Pharmaceutical, Kobayashi Pharmaceutical, Kowa, Kyowa Hakko Kirin, Meiji Seika Pharma, Mochida Pharmaceutical, NIHON PHARMACEUTICAL, Nippon Shinyaku, Ono Pharmaceutical, Shionogi, Mitsubishi Tanabe Pharma, Takara Bio, Taisho Pharmaceutical, Takeda, Teijin Pharma, Zeria Pharmaceutical and others.

Kobe Biomedical Innovation Cluster, Kurume Cutting-egde Medical Research Center, Metropolitan Bio Network, Mie's Comprehensive Special Zone for Life Innovation, Northern Advancement Center for Science & Technology, Osaka Bio Headquarter, Pharma Valley Center, Tottori Bio-Frontier and others.

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Participating Companies at BioJapan 2013

Asahi Glass, Chiyoda, DAICEL, Dainippon Screen MFG., FUJIFILM, IHI Plant Engineering, Hitachi Zosen, JSR Life Science, Kaneka, Kao, Kikkoman Biochemifa, Mitsubishi Chemical Corporation, Mizuho Information & Research Institute, Sapporo Breweries, Shiseido, Showa Denko, TOTO, and others.

Kyoto University, Nagoya University, Osaka University, Tohoku University, Tokyo Institute of Technology, Tokyo Medical and Dental University, Tsukuba University, University of Tokyo, Waseda University and others.

Partnering

AIST (National Institute of Advanced Industrial Science and Technology), CDRD (Centre for Drug Research

and Development), JETRO (Japan External Trade Organization), JST (Japan Science and Technology

Agency) , MOEA Taiwan (Ministry of Economic Affairs), NEDO (New Energy and Industrial Technology

Development Organization), Organization for Small & Medium Enterprises and Regional Innovation, Pasteur Institute, RIKEN and others.

Global Pharma (without Japanese pharma) AstraZeneca, Bayer Health Care, Eli Lilly, F. Hoffmann-La Roche, GlaxoSmithKline, Janssen Pharma, Lundbeck, MSD, Boehringer Ingelheim, Novartis, Pfizer and Sanofi.

Other Companies

National Research Institutes & Governmental Agencies

Academics


Online Partnering System

The BioJapan matching system will enable you to arrange meetings prior to the event. Create new partnerships and strengthen existing business relationships using the system!

Partnering

Before the event At the BioJapan

The 2014 BioJapan partnering is expected to attract 800+ companies. 9


Registration fee *Full Access*

Your registration fee covers: ･ Access to the BioJapan matching (partnering) system ･ Access to the exhibition & annex hall and partnering area ･ Wednesday Welcome Reception ･ Thursday Partnering Party

Registration fee: JPY50,000 (8% VAT excluded) per person *Approx. EUR 357.00 (Based on EUR1=JPY140.00 / as of Feb. )

Partnering

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System will open in Mid-July!

Partnering special: 14-minutes presentation in the exhibition hall available at the extra fee of JPY100,000 (approx. EUR 714).


Exhibition - General information Exhibition

Opportunity to promote your products and services to qualified participants, especially to participants from pharmaceutical companies!

Exhibition Categories;

-Drug and Drug discovery (Small-molecule drug, biologics and vaccine etc.)

-Drug Discovery support and contract services (Drug synthesis services, Analysis contract services

and Chemical compound libraries and screening etc.)

-Medical treatment, Diagnosis and Medical devices and equipment (Biomarkers and Gene therapy etc.)

-Research Devices, Reagents and Facilities (Research Devices, Bioinformatics and Bioimaging etc.)

-Others (Functional Food, Agriculture, Bio-cluster, Universities and Government Agencies etc.) 11


General Exhibition Fees and Benefits Exhibition

Exhibitor Benefits: 1) Partnering account(s) included depending on booth size 2) Company name listed in the BioJapan 2014 official guidebook 3) Company Directory listing on BioJapan 2014 website

Exhibition Fees: • Raw Space per 9 m2 : JPY 400,000 * • Exhibit Booth 9 m2 (incl. shell scheme) : JPY 500,000 * + Seminar 30 min. : JPY 250,000

• Meeting Booth 9 m2 (incl. shell scheme) : JPY 550,000 + Seminar 30 min. : JPY 250,000

• Trial Booth for 4 m2 : JPY190,000 + Seminar for 30 min. : JPY 100,000

• Academic package for 4 m2 : JPY 100,000

For details, see exhibitor prospects http://www.ics-expo.jp/biojapan/images/info_exhibitor/bj2014_info_en.pdf

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*open to Biotech companies and first time applicants.

*open to Academic Laboratories and TLO. / includes 30 min. Seminar slot.

*5 accounts per 9 m2 / 2 accounts per Trial booth (4 m2) / 1 account per 1 academic package.

*Early bird prices until March 31! (8% VAT excluded)

http://www.ics-expo.jp/biojapan/images/info_exhibitor/bj2014_info_en.pdf





Presentation Opportunities for exhibitors

BioJapan 2014 invites exhibitors to present at the conference.

Sponsored Seminar Exhibitor Presentation

Seminars

Exhibitor Presentation in the exhibition hall (Open space in Exhibition hall) ・ Regular Exhibitors： JPY 250,000 (approx. EUR 1,785) 30 min. ・ 4m2 package exhibitors： JPY 100,000 (approx. EUR 714) 30 min. ・ Academic Labs and TLO： JPY 50,000 (approx. EUR 357) 30 min.

Sponsored Seminar in the Annex hall (Closed seminar room in Annex hall) ・ Luncheon Seminar: JPY 1,200,000 (approx. EUR 8570) 60 min. ・ Sponsored Seminar: JPY 600,000 (approx. EUR 4,285) 60 min.

Note: The above cost does NOT include simultaneous interpretation service. 8% VAT not included, based on Based on EUR1=JPY140.00 / as of Feb. 2014

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・Bavarian Ministry of Economy(Germany) ・BioM (Germany) ・BioWin (Belgium) ・FlandersBio (Belgium) ・Embassy of Canada ・ONTARIO GOVERNMENT (Canada) ・EU-JAPAN CENTRE (EU) ・Germany Trade and Invest ・Holland Bio (Netherlands) ・Agency for the Assessment and Application of Technology (Indonesia) ・Invest Business Unit, Business Sweden ・National Research for Biopharmaceuticals, NRPB (Taiwan) ・Thailand Center of Excellence for Life Sciences “TCELS” ・Massachusetts Life Sciences Center (USA) ・State of North Carolina (USA) ・Ministry of education and science of the Russian Federation ・Russian Pharmaceutical and Medical Industries and more…

2013 Applicants: Governmental Organizations and Biotech Associations Exhibition

<Flanders Pavilion>

<GTAI seminar at exhibition hall>

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YEAR(JAN-DEC)

Business Opportunities in Japan

Company *Participated in the BioJapan 2013 partnering

Sales Figures

Operating profits

R&D *2 Spender

Takeda* 18.40 3.23 3.43

Astellas Pharma* 11.82 1.60 2.31

Daiichi Sankyo* 11.44 1.19 2.25

Otsuka Pharmaceutical 9.53 2.05 1.82

Eisai* 7.90 1.16 1.52

Mitsubishi Tanabe Pharma* 4.96 0.84 0.85

Chugai pharmaceutical* 4.55 0.76 0.68

Dainippon Sumitomo Pharma* 4.27 0.24 0.69

Kyowa Hakko Kirin* 4.19 0.56 0.54

Taisho Pharmaceutical* 3.30 0.46 0.29

Japan is currently the second-largest pharmaceuticals market in the world with growing demand for drugs due to high life expectancy and an aging population.

Total ethical drug sales in Japan based on NHI price levels *Unit: Billion USD

Japanese TOP 10 pharmaceutical companies based on FY2012 sales figures *Unit: Billion USD

Continued growth

Source: MR Biz Source: IMS Japan

*1: Total ethical drug sales 2011 in Japan based on NHI price levels were approximately 115.6 billion USD. *Based on exchange rates: USD1.00 = JPY 82.00 *2: Total R&D spending 2012 of Japanese top 10 pharmaceutical companies were approximately 14.38 billion USD. *Based on exchange rates: USD1.00 = JPY82.00,

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Market

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(Summary) Japanese Outbound M&A deals Market

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Company Takeover candidate Deal Value US $ Date

Ajinomoto Althea Technologies, Inc. (US) 166,2 million Mar. 2013

Otsuka Parmaceutical Claris Life Science (India) 194,1 million Dec. 2012

Takeda Envoy Therapeutics Inc. (US) 140 million Nov. 2012

Takeda LigoCyte Pharmaceuticals, Inc. (US) 492 million Nov. 2012

Takeda Maltilab (Brazil) 308,4 million May. 2012

Takeda URL Pharma (US) 800 million Apr. 2012

Asahi Kasei Zoll Medical (US) 2.21 billion Mar. 2012

Dainippon Sumitomo Boston Biomedical Inc.(US) 200 million Feb. 2012

Takeda Intellikine (US)190 million up front plus

120 million in contingent

milestones

Dec. 2011

Fujifilm SonoSite (US) 995 million Dec. 2011

Santen Pharma Novagali (France)135 million

(50.55% of the shares)Oct. 2011

Takeda Nycomed (Switzerland) 3.68 billion Sep. 2011

Shionogi C&O parmaseutical technology (China) 185 million Aug. 2011

Astellas and Maxygen

(US)Perseid Therapeutics (US) 76 million May 2011

Takeda Fate Therapeutics (US)Undisclosed

(Unspecified stake)May 2011

Taishio Parmaceutical Hoepharma Holdings (Malysia) 133,2 million Apr. 2011

Kyowa Hakko Kirin ProStrakan (UK) 474 million Apr. 2011

Daiichi Sankyo Plexxikon (US) 805 million Apr. 2011

Nitto Denko Avecia Biotech (US) Undisclosed Feb. 2011


(Summary) Drug Discovery Collaboration Market

Company Partner Release date

Otsuka Pharmaceutical (JPN) Living Cell Technologies Limited (Australia) Dec. 2012

Takeda (JPN) Advinu (India) Oct. 2012

Ono Pharmaceutical (JPN) Domain Therapeutics S.A. (France) Oct. 2012

Takeda (JPN) The BC Cancer Agency (Canada) Aug, 2012

Daiichi Sankyo (JPN) NGM Biopharmaceuticals, Inc. (US) Mar. 2012

Teijin Pharma (JPN) NovAliX (France) Jan. 2012

Astellas (JPN) and Agensys, Inc. (US) Seattle Genetics, Inc.(US) Jun. 2011

Eisai(JPN) UCL (UK) May 2011

Takeda (JPN) Heptares Therapeutics (UK) Apr. 2011

Takeda (JPN) Samyang Corporation (S. Korea) Apr. 2011

Daiichi Sankyo (JPN) Pieris AG (Germany) Apr. 2011

Eisai(JPN) Epizyme, Inc.（US) Mar. 2011

Astellas (JPN) Cell Signaling Technology, Inc.(US) Feb. 2011

Ono Pharmaceutical (JPN) BioFocus(UK) Jan. 2011

Eisai(JPN) FORMA Therapeutics (US) Nov. 2010

Ono Pharmaceutical (JPN) BioSeek (US) Mar. 2010

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Company Product Partner Biomass-based material from partner

Press release

Bridgestone Polyisoprene （Bio Tire） Ajinomoto Isoprene 2012

Toray Nylon 56 （Bio Nylon） Ajinomoto Pentane-1,5-diamine （from Lysine）

2012

Showa Denko

Biodegradable polyester resin “Bionolle”

Myriant（USA） Succinic acid 2012

Panasonic Eco Solutions

Bio-based resin for Kitchen Systems and Unit Bathrooms

DuPont Tate & Lyle Bio Products（USA）

Propanediol “Susterra” 2012

Toray Polyethylene terephthalate （Bio PET）

Gevo（USA） Para-xylene（Bio PX） 2011

Mitsubishi Chemical

Biomass-derived chemical products

Genomatica（USA）

1,4-butanediol 2011

Canon Bioplastic parts for Office Network Multifunction Devices

Toray Polylactic acid-based bioplastic “ECODEAR”

2010

NEC Bioplastic parts for Personal Computers

Kao Polylactic acid-based bioplastic “ECOLA”

2010

Recent Alliance in Bio-refinery

Source: Japan Bioindustry Association (JBA)

Topics


Thank you for your interest in BioJapan.

We look forward to seeing you in Yokohama.

CONTACT

BioJapan Secretariat Office

c/o ICS Convention Design, Inc.

Chiyoda Bldg., 1-5-18 Sarugaku-cho,

Chiyoda-ku, Tokyo 101-8449 Japan

TEL: 03-3219-3565

FAX: 03-3219-3628

E-MAIL: [email protected]

WEB: http://www.icsexpo.jp/biojapan/

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Asia’s Premier Partnering Event for the Biotechnology Industry