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“DESIGNER DRUGS” -“GETTING HIGH, SICK,
DISABLED, AND DEAD ON SYNETHETIC DRUGS”©
JUDGE KEVIN R. MADISONPRESIDING JUDGE LAKEWAY MUNICIPAL COURT
EMT-INTERMEDIATE (ADVANCED LIFESAVING)
FIREFIGHTER-FIRST RESPONDERFOR TEXAS MUNICIPAL COURTS EDUCATION CENTER
© COPYRIGHT JUDGE KEVIN R. MADISON
Educational Objectives At the end of this presentation, participants will be able to:
1. Understand why courts and court personnel should have a working knowledge of emerging drugs that impact cases tried by the court (PI,DOC, DUI, etc.), cases that judges review for issuance of arrest and search warrants, and in dealing with people who may be under the influence in court, which impacts courtroom security.
2. Understand the basic physiology of how these drugs affect behavior.
3. Identify some of the new designer drugs that are emerging throughout the U.S.
4. Describe some of the effects and signs of use of these designer drugs.
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Points about this presentation1. I am not an expert on this topic - I am not a Chemist or Biologist.
2. A class on Designer Drugs could easily last several days. This topic is very complex because it intertwines criminal jurisprudence, law enforcement, medicine, physiology, psychiatry, organic chemistry, and politics.
3. We have an very limited time so it is impossible to discuss all the different new designer drugs popping up across the country. We will touch on a few of the most common designer drugs. There are hundreds out there.
4. In light of our limited time, I will be happy to entertain any questions at the end of this presentation. Please write down your questions or comments that you would like to share and we will address these at the end of this presentation if time allows.
5. Because of the limited time (50 minutes) I encourage you to get on the Internet: Google, Medscape, National Institute on Drug Abuse (NIDA), and You Tube and explore this topic in greater detail on your own.
6. We should strive to know as much about Designer Drugs as the kids in our community know. 3
What are “Designer Drugs?”
• “Designer drugs” are chemicals that have been specifically made or “designed” by underground chemists so that they:
(1) are not covered by controlled substance statutes (and hence are not illegal), and
(2) still have the same “psychotropic affect” (cause stimulation, sedation, or hallucination, etc.) of the illegal popular drugs that people use.
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What are “Designer Drugs?”
Designer Drugs are drugs that are chemically created with different molecular structures than the original drugs that they imitate.
Example: synthetic marihuana called “Spice” or “K-2” is a chemical that mimics the chemical structure of THC in marihuana and its effects.
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syn·thet·icsinˈTHetik/
adjective: synthetic(of a substance) made by chemical synthesis, esp. to imitate a natural product. "synthetic rubber“
noun: synthetica synthetic material or chemical, esp. a textile fiber.
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How Psychoactive Substances Work
• Because of their chemical structure, alcohol and drugs have dramatic effects on receptor cells and neurotransmitters in Central Nervous System.
• Effects on:
– Mental processes
– Behavior
– Perception
– AlertnessSOURCE: NIDA. (2010). Drugs, Brains, and Behavior: The Science of Addiction.
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Our body and brain operate by maintaining, increasing, or decreasing chemicals and hormones that affects
Neuro-receptors and Neuro-transmitters
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For those who want to alter Sensation, Behavior, and Bodily Functions it’s all about ingesting drugs that affect neuroreceptors and neurotransmitters.
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How these drugs work
When absorbed into the body, drugs interact with and modify cells, organs, and bodily systems by:• Altering the way the body normally functions
(increasing, slowing, or enhancing bodily processes, or level or quality of functioning),
• Altering the operation of tissues, organs, and systems,
• Affecting hormones and enzymes, and• Impacting processes such as digestion,
respiration, circulation, and mental functioning.
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Commonly Used Psychoactive Substances
SOURCE: National Institute on Drug Abuse.
SUBSTANCE EFFECTS
Alcohol (liquor, beer, wine)
euphoria, stimulation, relaxation,lower inhibitions, drowsiness
Cannabinoids (marijuana, hashish)
euphoria, relaxations, slowed reaction time, distorted perception
Opioids (heroin, opium, many pain meds)
euphoria, drowsiness, sedation
Stimulants(cocaine, methamphetamine)
exhilaration, energy
Club Drugs (MDMA/Ecstasy, GHB)
hallucinations, tactile sensitivity, lowered inhibition
Dissociative Drugs (Ketamine, PCP, DXM)
feel separated from body, delirium, impaired motor function
Hallucinogens(LSD, Mescaline)
hallucinations, altered perception11
“Psychoactive” and “Psychotropic Drugs”
These drugs affect the brain, brain chemicals, and brain receptors.
These drugs are “mind altering” and affect a person’s mind and body because they are able to cross the blood-brain barrier, which many drugs cannot cross.
Alcohol, Marihuana, Cocaine, Heroin, Amphetamines are all examples of drugs that can cross the blood-brain barrier. 12
Problem with Designer Drugs
Although the chemical structure may be barely changed, the problem is that the properties of these drugs dramatically changes!
Super-enhanced properties of the drugs they copied: hyperactivity
hallucinationsparanoiasuperhuman strength
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Problem with Designer Drugs
Because molecular structure different these drugs are usually not illegal; however, legal does not mean safe!
New molecular structure creates whole new effects on mind and body:
increased heart rateheart attacksstrokes (brain attack)permanent brain injuries
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Close but no cigar!
Making one small change to a molecular structure of a compound can lead to drastic changes in the properties of that substance.
For example: H20 is water, of course.If you add another oxygen atom: H202The water becomes Hydrogen Peroxide, not poison but toxic and corrosive to human tissue...causes burns. Used for rocket fuel and making bombs.
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Designer Drugs
Bath Salts
Spice/K2
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Food and Drug Administration (FDA)
• Designer drugs do not have FDA approval and are produced by underground chemists who do not care about quality control of the product.
• Designer drugs are not correctly synthesized and purified.
• Designer drugs contain numerous toxic impurities not separated from the desired active ingredient after the synthesis was completed.
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Where do Designer Drugs come from?
• Chemical Research
• Published articles by Pharmaceutical Companies and Chemists
• Independent Chemists who love drugs
• “Basement Chemists”
• Made/imported from China and India then “assembled” and marketed in U.S.
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Underground Chemists
• Underground chemists first determine which drugs are listed in the jurisdiction’s controlled substance statute.
• Then these chemists make changes to the molecular structure of these drugs creating a slightly altered compound.
• May have very bad effects!• Legal Safe!!!!
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Common Characteristics of Designer Drugs
• Synthetic
• Marketed as something else – Incense, Bath Salts, Glass
Cleaner, Plant Food, Room Spray
• Attractive packaging
• Very small quantity (250mg-3gm) to obtain “high” thus many people overdose!
• “Not for human consumption”
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Common Characteristics of Designer Drugs
• White Powder or capsule
• No Ingredients listed
• Sold in Head Shop or Internet
• “Research Chemicals”
• “Does not contain . . .”
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Dangers of Bath Salts
• Abuse of recreational drugs sold as "bath salts" has sent an increasing number of people to hospitals in the United States and has resulted in deaths.
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What are Bath Salts?
• Synthetic Stimulant, similar to
ecstasy, cocaine and/or methamphetamine
• Derived from Cathinone from Khat plant
• “Not for human consumption”
• White, odorless, “pills”, fine-grained powder or crystals (oxidizes to yellow or tan)
• Can be ingested by snorting, smoking, swallowing, and intravenous access.
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Bath Salts a/k/a “K3”
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MDPV= Active compound
• Marketed as “Bath Salts”
• Chemical analog of Cathinone (Schedule 1 C.S.)
• Dose: 25mg – 500mg• CNS stimulant (up to 3 days)
– Delusional
– Seizures
– Restless / Irritated
– Inflammation of heart
– Teeth Grinding
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1 Dose Bath Salts…
DAY 1 Banging head into wall Pulled out IV twice Hallucinating, thought security
guard drank his beer
• HGN: 2• Pulse: 112 bpm• Blood Pressure: 144/94• Body Temperature: 98.5• Pupils: 9 – 10 mm in all lighting
conditions• Muscle Tone: Rigid
DAY 2• Combative• 12 people to control, injures 1
security guard• Lorazepam x 3, Haloperidol x1
to control• Moved to ICU• Combative again when woke
up
DAY 3• Resting pulse 120• Exhausted, no memory
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Effects of Bath Salts
DESIRED
• Euphoria
• Empathy/decreased hostility
• Hallucinations
• Increased insight/self-discovery
• Increased energy
• Enhanced music appreciation
WHAT REALLY HAPPENS
• Restless / irritated
• Delusional / paranoia
• Nose bleeds, headache
• Dilated pupils, blurred vision
• Blue/cold extremities
• Nausea/vomiting
• Seizures, teeth grinding
• Chest pain (inflamed heart)
• Excessive sweating
• Go to Jail 29
Synthetic Marijuana
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Synthetic Marihuana and Driving
Michigan Criminal Case APD#10-14949•Crossed raised median 3 times, hit concrete wall 2x, driving on sidewalk w/ broken axle / tire
•6HGN + vertical
•.000 BAC
•Hallucinating
•“Death is all around me”
•Going to kill Officer
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What is SPICE / K2 ?Dangerous, synthetic research chemicals that have been dissolved in acetone and sprayed onto dried plant material (herbs)
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SPICE/K2
• Plant material
• Marketed as incense
• Laced with various synthetic compounds that behave like THC
• Smoked or mixed in drink or food
• Was sold LEGALLY and LOCALLY
• 1g -3g packages About 2x price of marihuana
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Spice/K2
Ingredients: Baybean, Blue Lotus, Lion's Tail, Lousewort, Indian Warrior, Dwarf Scullcap, Maconha Brava, Pink Lotus, Marshmallow, Red Clover, Rose, Siberian Motherwort, Canavalia Maritime, Leonotis Leonurus, Leonurus Sibiricus, Pedicularis Densiflora, Scuttellaria Nana, Vanilla Planifolia, Zorinia Latifolia, Magnolia Officinalis, Rosa Gallica, Trifolium 35
Brands/Flavors
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SymptomsNot always a bad trip, but if you’re involved it probably is
•Elevated BP (140-210 / 100-110)
•Rapid heart rate (110-150bpm) – can be decreased BP / heart rate
•Tremors / Seizures
•Unconsciousness
•Hallucinations / Delusions / Paranoia
•Numbness / Tingling / Muscle Loss37
SymptomsNot always a bad trip, but if you’re involved it probably is
• Vomiting• Memory Loss • Incoherent/slurred
speech• May feel cold / hot • Excessive thirst• 6-8hr high (some
effects up to 30hrs)
Death??
• Cyclic Symptoms
• Effects vary from use to use and person to person
• “Excited Delirium”– No pain
– No clothes
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Emily Bauer Cypress, Texas
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Treatment?• No antidote
• Symptoms more like Stimulants and Dissociative Anesthetic than Marihuana
• Not detectable on standard screen
• Flush with Fluids (but not too much)
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NHTSA 2005-2009 StudyNHTSA Press Release # 16-10 Tuesday, November 30, 2010
Alcohol-related
incidents
Drug-related
incidents
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KratomAsian leaf 'kratom' making presence
felt in US emergency rooms (NBC News March 19, 2012)
opiate-like leaf from Southeast Asia is well known in the worlds of alternative medicine and the drug culture
dozens of companies selling kratom leaf and touting it as a way to combat fatigue, pain and depression — even as an antidote to heroin addiction
But in addition to its possible medicinal uses, kratomis beginning to show up in U.S. emergency rooms, with doctors saying they are dealing with people sick from taking it — especially teens who try it to get high 42
KratomAsian leaf 'kratom' making presence
felt in US emergency rooms (NBC News March 19, 2012)
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Kratom- Available now at your local “Head Shop” or “Smoke Shop”
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Kratom Sold Here
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Conclusion
Legal Safe!!!
Many items are legal, but dangerous.
Gasoline, rat poison, bleach, drain cleaner, spray paint, glue...
There are and will be hundreds and thousands of synthetic drugs...always morphing and changing.
Most synthetic drugs are more dangerous than the original drugs they copy/mimic.
Expect the unexpected when dealing with people under the influence of synthetics
Special ThanksKenneth Stecker
Michigan Traffic Safety
Resource Prosecutor
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