ANTIOXIDANT AUTHORITYHigh potency formulas to improve skin health and combat aging

1.OUR FOUNDATIONS

ANTIOXIDANT PIONEERCreated in 1997 thanks to the work of Dr Sheldon Pinnell – a renownedAmerican dermatologist, who was the first to stabilise pure Vitamin C at a high concentration and a low pH into a cosmetic solution – SkinCeuticals provides advanced anti-aging skincare breakthroughs at the forefront of antioxidant technology and helped pioneer the advent of cosmeceuticals* in the USA.

ANTI-AGING EXPERTSkinCeuticals’ mission is to improve skin health. Dedicated to this purpose, we make one simple promise - provide advanced skincare backed by science.Born from decades of skin cancer research, our high potency formulas are concentrated in pure actives and proven to penetrate optimally into skin. Made in the USA, we are used and recommended by dermatologists and plastic surgeons, select pharmacies and premium spas to both correct the signs of aging and prevent future damage.

THE MEDISPA REFERENCESkinCeuticals is used in cabin treatments together with professional skincare protocols and clinical procedures. The brand is recommended by the best dermatologists and plastic surgeons and SkinCeuticals is now distributed by close to 4,000 dispensing clinics and medispas around the world.

*Cosmeceuticals are products that are at the frontier between cosmetics and drugs.

4 GENERATIONS OF ANTIOXIDANT BREAKTHROUGHS10 ANTIOXIDANT PATENTS AND 20+ PEER-REVIEWED STUDIES

2. OUR PHILOSOPHY A 3-STEP ANTI-AGING ROUTINE

There are three fundamental steps to prevent and to correct signs of aging caused by environmental assaults and UV exposure.

PREV

ENT ANTIOXIDANT SERUMS

Neutralize free radicals generated as a reaction to environmental attacks (UV rays, pollution, stress, smoke).Act to reinforce the skin’s natural antioxidant defences against free radicals.

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T SPECIFIC CORRECTIVE TREATMENTSRepair the skin thanks to powerful formulas enriched with reparative, brightening and exfoliating active ingredients, derived from dermatological practices and formulated in optimal concentrations, proven to penetrate optimally into skin.

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T SUNSCREENS (Broad-spectrum filters)Form a barrier against damaging UVA/UVB rays, responsible for the acceleration of natural aging.Act on the surface of the skin, to protect skin from free radical attacks, in order to complement the action of antioxidants.

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3. OUR MODEL INTEGRATED SKINCARE

At SkinCeuticals we believe the best way to improve skin health is to protect skin, prevent future damage, and correct existing aging through cosmetic procedures, professional treatments, and home care products that support the skincare goals of physicians and patients.

2 ways of using SkinCeuticals products by professionals:

PROFESSIONAL SKINCARE PROTOCOLS/FACIALS Protocols with SkinCeuticals products only

CLINICAL PROCEDURES Procedures in combination with SkinCeuticals products Example: laser, peel, botox, filler, medical needling

3 ways of using SkinCeuticals products as home care:

PRE-CONDITION Preparation for cosmetic procedures

POST-PROCEDURE To enhance results and/or soothe skin

DAILY-USE

PROFESSIONAL USE HOME CARE

HOME CARE PRE-CONDITION

PROFESSIONALSKINCARE

PROTOCOLS

COSMETIC PROCEDURES

HOME CARE DAILY-USE

HOME CARE POST-PROCEDURE

PHLORETIN CF & C E FERULIC REVERSE EX IST ING DAMAGE, STOP THE AGING RELAPSE

AN ANTIOXIDANT A DAY KEEPS SKIN AGING AWAY Excessive exposure to ultraviolet light as well as the natural aging process depletes the body of its internal supply of antioxidants. SkinCeuticals’ topical antioxidants prevent oxidative damage.

SkinCeuticals’ 30 years of academic research have demonstrated that, for a topical antioxidant to be efficient: Penetration needs to be proven Specific antioxidant combinations provide superior results to single AOX formulations Biological effects in skin have to be demonstrated – by analysing key biomarkers

C E Ferulic and Phloretin CF increase the body’s antioxidant natural reservoir to provide unmatched protection from the sun. The additional benefit: improved radiance and texture, reduced lines and wrinkles. Each combination has its own specificities.

PREVENT

P53, an essential protective tumor protection suppression protein in skin,is increased when skin is damaged.In vivo, skin protected with Phloretin CF shows significantly lower levels of P53 compared to placebo.

C E Ferulic yields 8x the skin’s natural protection from the sun.

C E FERULIC15% L-Ascorbic Acid, 1% a-Tocopherol, 0,5% Ferulic Acid Protects the lipidic film Stimulates collagen synthesis to improve firmness and elasticity Ideal for normal to dry skin

PHLORETIN CF2% Phloretin, 10% L-Ascorbic Acid, 0,5% Ferulic Acid Boosts skin’s structure Diminishes age and brown spots Ideal for combination to normal skin

Controlled delivery for enhanced tolerance

ULTRA FACIAL DEFENSE SPF 50& SHEER MINERAL UV DEFENSE SPF 50 BROAD SPECTRUM PROTECTION

DAILY UVA/UVB EXPOSURE ACCELERATES SKIN AGING UVB rays are responsible for sunburn

UVA rays represent 95% of the UV that reaches our skin all year round and generate free radicals

Oxidation of skin’s pigment: skin darkening and more visible brown spots

Damage to fibroblasts (cells that produce collagen and elastin) inducing wrinkles and loss of firmness

SHEER MINERAL UV DEFENSE SPF 50100% mineral filters

Designed for all skin types, even very sensitive, oily or acne-prone skin

Ultra-fluid, matifying texture

Transparent finish, water and sweat resistant

Paraben-free, chemical-filter free: ideal for compromised skin after cosmetic procedures

ULTRA FACIAL DEFENSE SPF 50Mexoryl® SX/XL, Tinosorb® S,Titanium Dioxide

Designed for all skin types, hypoallergenic and non-comedogenic formula

Ultra-light texture with long-lasting hydration (12 hours)

Good make-up base: no whitish effect

Fragrance free

PROTECT

SkinCeuticals also provides a complete corrective product line that combines powerful formulas enriched with reparative, brightening and exfoliating ingredients to help improve your patients’ skin.

AS EFFECTIVE AS TRETINOIN* WITH SIGNIFICANTLY BETTER RESULTS IN 3 KEY ATTRIBUTES:

THE INTERSECTION BETWEEN BLEMISHES AND AGING After years of effective but dehydrating and sensitizing drug therapies, many adults suffering from blemishes are ready to transition to a more tolerable yet efficient solution to treat breakouts while improving overall complexion.

*Study carried out on 18-40 year old males and females with mild to moderate acne(at least 4 inflammatory lesions and seven non-inflammatory lesions, no cysts), mildto moderate fine lines and wrinkles, 8 weeks of treatment.

BLEMISH & AGE DEFENSE SO EFF ICIENT ON IMPERFECTIONS, IT GOES BEYOND TO TREAT S IGNS OF AGING

CORRECT

ANTI-IMPERFECTIONS ANTI-AGING1,5% Salicylic Acid

0,3% LHA3,5% Glycolic Acid

0,5% Citric Acid

2%DIOICACID

Blemish + Age Defense is shown to be stat is t ical ly bet ter than Tret inoin in improving skin tone (weeks1,4 and 8) and blotchiness (weeks 4 and 8) and in reducing total lesions (weeks 1 and 8).

RETAILINTERNATIONAL PRODUCT LINEA COMPLETE AND HIGH POTENCY ANTI-AGING SKINCARE LINE

PREVENT

PROTECT

High potency antioxidantformulas designed toprevent skin damage fromthe inside

Broad-spectrumprotection from damagingUVA and UVB rays

CORRECT

MOISTURIZE

CLEANSE & TONE

Formulas enriched with reparative, exfoliatingand brightening ingredients for advanced correction

Formulas enriched with multifunctional ingredientsto hydrate and nourish

Formulas containing a variety of active ingredients to lift impurities and gently exfoliate dead skin cells

GENTLE CLEANSER EQUALIZINGTONER

BLEMISH & AGE SOLUTION

BLEMISH & AGE CLEANSING GEL

SIMPLY CLEAN

EMOLLIENCE HYDRATING B5

ULTRA FACIALDEFENSE SPF 50

SHEER MINERAL UVDEFENSE SPF 50

BRIGHTENING UV DEFENSE SPF 30

HYDRATING B5 MASQUE

C E FERULIC

DAILY MOISTURE

PHYTO CORRECTIVE

A.G.E EYECOMPLEX

A.G.EINTERRUPTER

RETEXTURING ACTIVATOR

EYE BALM

FACE BALM

FACE CREAM

CLARIFYINGCLAY

MASQUE

BLEMISH & AGE DEFENSE

RETINOL 0.3

PIGMENTREGULATOR

PHLORETIN CF PHLORETIN CF GEL AOX+ EYE GEL

MICRO POLISH

PREVENT

PROTECT

CORRECT

MOISTURIZE

CLEANSE & TONE

BRIGHTENING UVDEFENSE SPF 30

PROINTERNATIONAL PRODUCT LINEA COMPLETE AND HIGH POTENCY ANTI-AGING SKINCARE LINESkinCeuticals provides professional-size products and protocols that have been developed to achieve the highest standards in cosmetic treatments.

High potency antioxidantformulas designed toprevent skin damage fromthe inside

Broad-spectrumprotection from damagingUVA and UVB rays

Formulas enriched with reparative, exfoliatingand brightening ingredients for advanced correction

Formulas enriched with multifunctional ingredientsto hydrate and nourish

Formulas containing a variety of active ingredients to lift impurities and gently exfoliate dead skin cells

GENTLE CLEANSER EQUALIZING TONER BLEMISH & AGE SOUTION

BLEMISH & AGE GEL

SIMPLY CLEAN

EMOLLIENCE HYDRATING B5 HYDRATING B5MASQUE

DAILY MOISTURE

EYE BALM

FACE BALM

FACE CREAM

PHYTO CORRECTIVE

RETEXTURING ACTIVATOR

CLARIFYINGCLAY

MASQUE

VITAMIN C FIRMINGMASQUE

PIGMENT BALANCING PEEL

(Booster, Solution, Powder)

C E FERULIC PHLORETIN CF

BLEMISH & AGE

DEFENSE

PEEL NEUTRALIZER

A.G.EINTERRUPTER

A PROFESSIONAL MEDICAL NETWORK EXPANDING WORLDWIDESkinCeuticals is present in the following countries:Austria, Brazil, Canada, China, Colombia (2012),United Arab Emirates, France, Germany, Hong Kong, Italy, Japan, Korea, Lebanon, Mexico (2012), Poland, Portugal, Russia, Singapore, Saudi Arabia, South Africa (2012), Spain, Turkey, United Kingdom, USA. ©

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