2
Flow Cytometry Panels CLL/SLL ZAP-70 Analysis CD3, CD5, CD19, ZAP-70 Lymphoproliferative Disorders Analysis CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD11c, CD19, CD20, CD23, CD38, CD45, CD56, CD57, FMC-7, Kappa, Lambda Myeloid/Lymphoid Disorders and Acute Leukemia Analysis CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD11b, CD11c, CD13, CD14, CD16, CD19, CD20, CD22, CD23, CD33, CD34, CD38, CD45, CD56, CD57, CD64, CD117, FMC-7, HLA-DR, Kappa, Lambda Plasma Cell Analysis CD19, CD20, CD38, CD45, CD56, CD117, CD138, cIgA, cIgG, cIgM, sIgM, cKappa sKappa, cLambda, sLambda PNH Panel CD14, CD16, CD45, CD55, CD59, FLAER, Glycophorin-A Residual CLL/SLL CD5, CD11c, CD19, CD19/5, CD20, CD23, CD45, CD52, Kappa, Lambda Immunohistochemistry Panels Acute Leukemia Panel CD3, CD10, CD20, CD34, CD56, CD61, CD79a, CD117, Glycophorin-A, HLA-DR, MPO, TdT Adenocarcinoma vs. Mesothelioma BerEP4, Calretinin, CD68, CEAm, Desmin, GLUT-1, MOC31, Napsin A, TTF-1 Breast carcinoma, R/O Invasion Panel Calponin, CD10, p63, SMM-HWC Germ Cell Tumor AFP, CAM 5.2, CD30, CD117, HCG, Oct 3/4, PLAP, Podoplanin, SALL4 GIST Panel Actin, CD34, CD117, DOG-1, S100, SMA Hepatocellular vs. Cholangiocarcinoma vs. Metastatic Carcinoma AFP, CA19.9, CAM 5.2, CDX2, CEAm, CK7, CK20, Glypican-3, Hepatocyte, PODXL-1, TTF-1 Hodgkin Lymphoma Profile CD3, CD15, CD20, CD30, CD45, CD79a, EBV, Fascin, PAX-5 Lung NSCLC Profile: Adenocarcinoma vs. Squamous Cell Carcinoma CK5/6, Napsin A, p40, TTF-1 Microsatellite Instability (MSI) MLH1, MSH2, MSH6, PMS2 Neuroendocrine Neoplasm CAM 5.2, CD56, Chromogranin, Ki-67, Synaptophysin, TTF-1 NHL vs. Reactive Hyperplasia, Lymphoma Panel BCL-2, BCL-6, CD3, CD5, CD10, CD20, CD23, CD43, CD79a, Cyclin D1, Kappa, Ki-67, Lambda Plasma Cell Dyscrasia/Multiple Myeloma CD20, CD45, CD56, CD79a, CD138, Cyclin D1, IgA, IgG, IgM, Kappa, Lambda Prostate Cancer Profile CK903, p504S, p63 Spindle Cell Neoplasm Panel Actin, AE1/AE3, CD34, CD68, CD117, Desmin, Factor XIIIa, Ki-67, S100, SMA, Vimentin Tumor of Unknown Primary (Female) AE1/AE3, CA19.9, CA125, CD45, CDX2, CEAm, CK7, CK20, ER, GCDFP-15, Hepatocyte, p63, PAX-8, PR, Renal Cell, S100, TTF-1 Tumor of Unknown Primary (Male) AE1/AE3, CA19.9, CD45, CDX2, CK7, CK20, Hepatocyte, Napsin A, p63, PSA, PSMA, Renal Cell, S100, TTF-1 Special Stains Acid Fast Bacilli (AFB), Alcian Blue, Congo Red (amyloid), Elastic, Fite’s Acid Fast Stain, Giemsa, Gomori Methenamine Silver (GMS), Gram Stain, Hale’s Colloidal Iron, Iron, Myeloperoxidase (MPO), Mucicarmine, Nonspecific Esterase (NSE), PAS, PAS-D, Reticulin, Trichrome, Warthin-Starry Shipping to GenPath GenPath provides all shipping materials and uses a courier to pick up specimens in selected areas. GenPath pays all shipping charges via FedEx for non-courier accounts. Call 800 627 1479 to order additional shipping kits. Instructions for Shipping 1. Label the specimen(s) with the patient’s name, date and time of collection. 2. Complete the Requisition Form. Please be sure to fill in all fields of information, including the patient’s demographics and billing information. 3. Verify that the appropriate specimen requirements have been met (sample type, volume, collection tube type). 4. Place specimens and completed requisition form in Shipping Kit. 5. For courier service: Place Shipping Kit into Biohazard Bag and seal. Call GenPath at 800 627 1479 for courier pickup. 6. For FedEx service: Place Shipping Kit in FedEx Diagnostic Kit and seal. Complete and attach FedEx Airbill. Mark for Saturday delivery if shipping on Friday. Call FedEx for pickup at 800 463 3339 and call GenPath Client Services Department with Airbill Number at 800 627 1479. Contacting GenPath GenPath Client Service Representatives Monday–Friday 8:30 am to 9:00 pm (Eastern Time) 800 627 1479 Saturday 9 am to 5 pm BioReference Client Service Representatives Monday–Friday 24 Hours 800 229 5227 481 Edward H Ross Drive Elmwood Park NJ 07407 1 800 627 1479 tel | 1 201 791 8760 fax www.genpath.com A business unit of BioReference Laboratories, Inc. © 2013 BioReference Laboratories, Inc. All rights reserved. 19912 – 02/13 Antibody Library NEW PROFILE

Antibody Library - GenPath Diagnostics | We see … Library NEW PROFILE Ksp-cadherin MRQ-33 IHC Overexpressed in renal oncocytoma and chromophobe carcinoma Lambda Lamb14 IHC Immoglobulin

  • Upload
    hathu

  • View
    220

  • Download
    0

Embed Size (px)

Citation preview

Page 1: Antibody Library - GenPath Diagnostics | We see … Library NEW PROFILE Ksp-cadherin MRQ-33 IHC Overexpressed in renal oncocytoma and chromophobe carcinoma Lambda Lamb14 IHC Immoglobulin

Flow Cytometry PanelsCLL/SLL ZAP-70 AnalysisCD3, CD5, CD19, ZAP-70

Lymphoproliferative Disorders AnalysisCD2, CD3, CD4, CD5, CD7, CD8, CD10, CD11c, CD19, CD20, CD23, CD38, CD45, CD56, CD57, FMC-7, Kappa, Lambda

Myeloid/Lymphoid Disorders and Acute Leukemia AnalysisCD2, CD3, CD4, CD5, CD7, CD8, CD10, CD11b, CD11c, CD13, CD14, CD16, CD19, CD20, CD22, CD23, CD33, CD34, CD38, CD45, CD56, CD57, CD64, CD117, FMC-7, HLA-DR, Kappa, Lambda

Plasma Cell AnalysisCD19, CD20, CD38, CD45, CD56, CD117, CD138, cIgA, cIgG, cIgM, sIgM, cKappa sKappa, cLambda, sLambda

PNH PanelCD14, CD16, CD45, CD55, CD59, FLAER, Glycophorin-A

Residual CLL/SLLCD5, CD11c, CD19, CD19/5, CD20, CD23, CD45, CD52, Kappa, Lambda

Immunohistochemistry PanelsAcute Leukemia PanelCD3, CD10, CD20, CD34, CD56, CD61, CD79a, CD117, Glycophorin-A, HLA-DR, MPO, TdT

Adenocarcinoma vs. MesotheliomaBerEP4, Calretinin, CD68, CEAm, Desmin, GLUT-1, MOC31, Napsin A, TTF-1

Breast carcinoma, R/O Invasion PanelCalponin, CD10, p63, SMM-HWC

Germ Cell TumorAFP, CAM 5.2, CD30, CD117, HCG, Oct 3/4, PLAP, Podoplanin, SALL4

GIST PanelActin, CD34, CD117, DOG-1, S100, SMA

Hepatocellular vs. Cholangiocarcinoma vs. Metastatic CarcinomaAFP, CA19.9, CAM 5.2, CDX2, CEAm, CK7, CK20, Glypican-3, Hepatocyte, PODXL-1, TTF-1

Hodgkin Lymphoma ProfileCD3, CD15, CD20, CD30, CD45, CD79a, EBV, Fascin, PAX-5

Lung NSCLC Profile: Adenocarcinoma vs. Squamous Cell CarcinomaCK5/6, Napsin A, p40, TTF-1

Microsatellite Instability (MSI)MLH1, MSH2, MSH6, PMS2

Neuroendocrine NeoplasmCAM 5.2, CD56, Chromogranin, Ki-67, Synaptophysin, TTF-1

NHL vs. Reactive Hyperplasia, Lymphoma PanelBCL-2, BCL-6, CD3, CD5, CD10, CD20, CD23, CD43, CD79a, Cyclin D1, Kappa, Ki-67, Lambda

Plasma Cell Dyscrasia/Multiple MyelomaCD20, CD45, CD56, CD79a, CD138, Cyclin D1, IgA, IgG, IgM, Kappa, Lambda

Prostate Cancer ProfileCK903, p504S, p63

Spindle Cell Neoplasm PanelActin, AE1/AE3, CD34, CD68, CD117, Desmin, Factor XIIIa, Ki-67, S100, SMA, Vimentin

Tumor of Unknown Primary (Female)AE1/AE3, CA19.9, CA125, CD45, CDX2, CEAm, CK7, CK20, ER, GCDFP-15, Hepatocyte, p63, PAX-8, PR, Renal Cell, S100, TTF-1

Tumor of Unknown Primary (Male)AE1/AE3, CA19.9, CD45, CDX2, CK7, CK20, Hepatocyte, Napsin A, p63, PSA, PSMA, Renal Cell, S100, TTF-1

Special StainsAcid Fast Bacilli (AFB), Alcian Blue, Congo Red (amyloid), Elastic, Fite’s Acid Fast Stain, Giemsa, Gomori Methenamine Silver (GMS), Gram Stain, Hale’s Colloidal Iron, Iron, Myeloperoxidase (MPO), Mucicarmine, Nonspecific Esterase (NSE), PAS, PAS-D, Reticulin, Trichrome, Warthin-Starry

Shipping to GenPathGenPath provides all shipping materials and uses a courier to pick up specimens in selected areas. GenPath pays all shipping charges via FedEx for non-courier accounts.Call 800 627 1479 to order additional shipping kits.

Instructions for Shipping1. Label the specimen(s) with the patient’s name, date and time of collection.

2. Complete the Requisition Form. Please be sure to fill in all fields of information,

including the patient’s demographics and billing information.

3. Verify that the appropriate specimen requirements have been met (sample type,

volume, collection tube type).

4. Place specimens and completed requisition form in Shipping Kit.

5. For courier service: Place Shipping Kit into Biohazard Bag and seal. Call GenPath

at 800 627 1479 for courier pickup.

6. For FedEx service: Place Shipping Kit in FedEx Diagnostic Kit and seal. Complete

and attach FedEx Airbill. Mark for Saturday delivery if shipping on Friday. Call

FedEx for pickup at 800 463 3339 and call GenPath Client Services Department

with Airbill Number at 800 627 1479.

Contacting GenPath

GenPath Client Service RepresentativesMonday–Friday 8:30 am to 9:00 pm (Eastern Time) 800 627 1479Saturday 9 am to 5 pm

BioReference Client Service RepresentativesMonday–Friday 24 Hours 800 229 5227

481 Edward H Ross Drive Elmwood Park NJ 074071 800 627 1479 tel | 1 201 791 8760 fax

www.genpath.comA business unit of BioReference Laboratories, Inc.

© 2013 BioReference Laboratories, Inc. All rights reserved. 19912 – 02/13

Antibody Library

NEW PROFILE

Page 2: Antibody Library - GenPath Diagnostics | We see … Library NEW PROFILE Ksp-cadherin MRQ-33 IHC Overexpressed in renal oncocytoma and chromophobe carcinoma Lambda Lamb14 IHC Immoglobulin

Ksp-cadherin MRQ-33 IHC Overexpressed in renal oncocytoma and chromophobe carcinomaLambda Lamb14 IHC Immoglobulin light chain lambdaLambda-ISH ISH ISH ISH Immunoglobulin light chain lambdacLambda 1-155-2 Flow Lambda Ig light chain, B-cells, plasma cellssLambda Polyclonal Flow Surface lambda Ig light chainLaminin Polyclonal IHC Basement membrane lamininLewis Y F3 IHC Blood group related antigenLH Polyclonal IHC Luteinizing hormone, pituitaryMacrophage HAM56 IHC Reacts with tangible macrophages, interdigitating macrophages of lymph nodes

and tissue macrophages.Mammaglobin 31A5 IHC Breast terminal duct and lobular epitheliumMelan A A103 IHC Melanoma-associated marker, adrenocortical tumorsMelanosome HMB45 IHC Melanoma-associated marker; angiomyolipomasMesothelin 5B2 IHC Mesotheliomas, non-mucinous ovarian and squamous tumors of esophagus and

cervixMITF C5/D5 IHC Microphthalmia transcription factor, melanoma, melanocytesMLH1 G168-728 IHC Mismatch repair proteinMSH2 G219-1129 IHC Mismatch repair proteinMSH6 44 IHC Mismatch repair proteinMUC1 H23 IHC Membrane bound, glycosylated phosphoprotein MUC1MUC-2 MRQ-18 IHC Gastrointestinal, other rare carcinomasMUC5AC MRQ-19 IHC Pancreatic adenocarcinoma, other carcinomasMUC6 MRQ-20 IHC High molecular weight glycoprotein, preferentially expressed in GI and

pancreaticobilaryMUM-1 MRQ-8 IHC Late stage B-cells, plasma cells, activated T-cellsMuramidase Polyclonal IHC Lysozyme, monocytic cellsMyeloperoxidase Polyclonal IHC MyeloperoxidaseMyogenin F5D IHC Muscle marker, positive in rhabdomyosarcomaMyoglobin Polyclonal IHC Striated and cardiac muscleNapsin A Polyclonal IHC Type II pneumocytes, pulmonary adenocarcinomaNF 2F11 IHC NeurofilamentNSE E27 IHC Neuron-specific enolaseOCT2 MRQ-2 IHC B-cell transcription factorOCT 3/4 MRQ-10 IHC Germ cell tumorsp16 E6H4 IHC Cyclin-dependent kinase inhibitor; CIN/high grade SILP21 DCS-60.2 IHC Cyclin-dependent kinase inhibitorp40 Polyclonal IHC Amino acids 5-17 of p40; Most frequently used marker for lung squamous cell

carcinomap53 D07 IHC Tumor suppressor gene mutationp57 KP10 IHC Inhibitor of G1 cyclin complex/negative regulator of cell proliferationp63 4A4 IHC Prostatic basal cells, breast myoepithelial cellp120 Catenin MRQ-5 IHC Intracytoplasmic Accumulation in Lobular Mammary CarcinomaP504S 13H4 IHC Prostatic carcinoma and high grade PINParvovirus B19 R92F6 IHC Parvovirus B19PAX-2 Polyclonal IHC Renal cell carcinoma subsets, Wilm’s tumorPAX5 SP34 IHC Expressed primarily in pro-, pre-, and mature B-cells and Hodgkin cellsPAX-8 Polyclonal IHC Ovarian serous carcinoma, thyroid and renal carcinoma, seminomaPD1 MRQ-22 IHC CD28 Receptor Family; Angioimmunoblastic LymphomaPerforin MRQ-23 IHC NK cells, activated CD8+ T-cellsPLAP NB10 IHC Placental alkaline phosphatase; germ cell tumors and adenocarcinoma subsetPMS2 EPR3947 IHC Mismatch Repair ProteinPodoplanin D2-40 IHC Lymphatic endotheliumPODXL-1 4F10 IHC Podocalyxin-like protein 1, ampullary and pancreatic adenocarcinoma subsetPR 1E2 IHC Progesterone receptorProlactin Polyclonal IHC Pituitary hormonePSA ER-PR8 IHC Prostate specific antigenPSAP/HPAP PASE/4LJ IHC Human prostatic acid phosphatasePSMA 3E6 IHC Prostate specific membrance antigen, overexpressed in prostate carcinomaPTEN 6H2.1 IHC Tumor suppressor genePTH MRQ-31 IHC Parathyroid hormoneRenal cell PN-15 IHC Renal epithelial cell originS100 Polyclonal IHC Neural crest derivativesSALL4 6E3 IHC Germ cell tumors, including yolk sac tumors, embryonal carcinoma, seminomaSMA 1A4 IHC Smooth muscle actin, myoepithelial and myofibroblastic cellsSMM-HWC SMMS-1 IHC Smooth-muscle myosin heavy-chainSomatostatin Polyclonal IHC Islet cell tumorsSpirochete Polyclonal IHC Treponema Pallidum (syphilis)Surfactant 32E12 IHC Lung non-small cell carcinomasSynaptophysin SP11 IHC Neural and endocrine tissuesTAG-72 B72.3 IHC Simple Epithelium, AdenocarcinomaTCL-1 MRQ-7 IHC T-cell prolymphocytic markerTCRαβ WT31 Flow T-cell receptor heterodimer complex, major T-cell subsetTCRγδ 11F2 Flow T-cell receptor heterodimer complex, major T-cell subsetTdT Polyclonal IHC Terminal deoxynucleotidyl transferase, precursor B-cells and thymocytesTdT HT6 Flow Cortical thymocytes, precursor B-cellsTFE3 Polyclonal IHC Xp11.2 translocation, alveolar soft part sarcoma, renal carcinoma subsetThrombomodulin 1009 IHC Mesothelioma, some epithelial tumorsThyroglobulin 2H11+6E1 IHC ThyroglobulinTIA-1 TIA-1 IHC Stress granules, cytotoxic granules of resting & activated T-cellsToxoplasma Polyclonal IHC Toxoplasma gondii protozoaTRAP 9C5 IHC Tartrate Resistant Acid PhosphataseTryptase G3 IHC Mast cell tryptase, mast cellsTSH Polyclonal IHC Thyroid stimulating hormone, subset of pituitary tumorsTTF1 8G7G3/1 IHC Thyroid Transcription Factor-1; thyroid and lung tumorsTyrosinase T311 IHC MelanomaUroplakin AU1 IHC Urothelial carcinomaVillin CWWB1 IHC Gastrointestinal mucosal epithelium brush borderVimentin V9 IHC Cytoplasmic intermediate filament; mesenchymal cells and some epithelial tumorsWilm’s Tumor (WT-1) 6F-H2 IHC Desmoplastic SRCT, methothelioma, Mullerian tumors, Wilm’s tumorZAP-70 1E7.2 Flow Prognostic factor in CLL/SLLZAP-70 2F3.2 IHC Zeta-associated T-cell tyrosine kinase, CLL/SLL subset

CD79a SP18 IHC B-cells, plasma cellsCD79a HM47 Flow B-cells, plasma cellsCD99 O13 IHC PNET, Ewing’s sarcomaCD103 Ber-ACT8 Flow Activated cells, hairy cell leukemiaCD117 YR145 IHC c-kit ligand, myeloid and mast cell marker, GISTCD117 104D2 Flow Stem cell receptor (c-kit), myeloid cellsCD123 9F5 Flow Dentritic cell markerCD123 BR4MS IHC Plasmacytoid dendritic cells, plasmacytoid monocytesCD138 B-A38 IHC Plasma cells and epithelial cell subsetCD138 MI15 Flow Plasma cellsCD163 MRQ-26 IHC Macrophages, monocytesCDX2 EPR2764Y IHC Carcinoma subset; intestinal-type tumorsCEA monoclonal TF3H8-1 IHC Carcinoembryonic antigen, adenocarcinomaCEA polyclonal Polyclonal IHC Carcinoembryonic antigen, adenocarcinomaChromogranin A LK2H10 IHC Neuroendocrine markersCK5/6 D5/16B4 IHC Squamous and mesothelial cellsCK7 SP52 IHC Carcinoma subsetCK8 35BetaH11 IHC LMW cytokeratin, non-squamous cell tumorsCK 8/18 B22.1/B22.3 IHC Paget cellsCK14 LL002 IHC Squamous epithelia, renal oncolytic tumors, metaplastic breast carcinomaCK17 KS 17.E3 IHC Carcinoma subset (including pancreaticobiliary)CK19 A53-B/A2.26 IHC Carcinoma subset (including pancreatobilary); 46 kD keratinCK20 SP33 IHC Carcinoma subset (GI, others); 46 kD keratinCK903 34ßE12 IHC High molecular weight cytokeratinc-MET SP44 IHC Transmembrane tyrosine kinase receptorCMV DDG9/CCH2 IHC CytomegalovirusCollagen IV CIV22 IHC Type IV collagen, basement membrane proteinCOX-2 SP21 IHC Cyclooxygenase enzyme, upregulated in many tumorsCyclin D1 (BCL-1) SP4-R IHC Cyclin D1/PRAD1, mantle cell lymphomaDesmin DE-R-11 IHC Striated and smooth muscle cellsDOG-1 SP31 IHC Gastrointestinal stromal tumorEBER ISH PROBE ISH Inform EBER probe for Epstein-Barr virusEBV (LMP-1) CS 1-4 IHC Epstein-Barr virus LMP (latent membrane protein)E-Cadherin 36 IHC Epithelial cells; ductal-type breast carcinomaEGFR 3C6 IHC Epidermal growth factor receptorEMA E29 IHC Epithelial membrane antigenEpCam MOC-31 IHC Adenocarcinoma, columnar epitheliumER SP1 IHC Estrogen receptorERCC-1 8F-1 IHC Excision repair cross-complementation group 1Factor VIIIRA Polyclonal IHC Von Willebrand receptor; megakaryocytes and endotheliumFactor XIIIa AC-1A1 IHC Fibrohistiocytic and dermal dendritic cellsFascin 55K-2 IHC Classical Hodgkin lymphoma, Dendritic meshworkFLAER N/A Flow Fluorescent-labeled inactive toxin aerolysinFLI-1 MRQ-1 IHC Ewing sarcoma/peripheral primitive neuroectodermal tumor, endothelial cellsFMC7 FMC7 Flow Distinguish typical B-cell CLL from other B-cell non-Hodgkin lymphomasFOXP3 236A/E7 IHC Forkhead Box P3; immune modulator of T-cellsFSH Polyclonal IHC Follicle Stimulating Hormone, PituitaryGastrin Polyclonal IHC Carcinoid and islet cell tumorsGATA-3 L50-823 IHC Transcription factor that regulates the development and subsequent

maintenance of multiple tissuesGCDFP-15 EP1582Y IHC Gross cystic disease fluid protein, breast tumors, othersGFAP EP672Y IHC Glial fibrillary acidic proteinGH Polyclonal IHC Growth hormone, pituitary adenomaGlucagon Polyclonal IHC Islet cell tumorGLUT-1 Polyclonal IHC Glucose transporter type I, overexpressed in mesothelioma and other cancersGlycophorin-A GA-R2 IHC Erythroid cellsGlycophorin-A CLB-ery-1 Flow Erythroid cellsGlypican-3 1G12 IHC GPC3, Hepatocellular Carcinoma, Germ Cell TumorsGranzyme B POLYCLONAL IHC Cytotoxic T-lymphocytes and NK cellsH. Pylori Polyclonal IHC Distinguish H. Pylori from other types of curved bacteriaHBcAg Polyclonal IHC Hepatitis B core antigenHBME-1 HBME-1 IHC Mesothelial cells, adenocarcinoma subsetHBsAg S1-210 IHC Hepatitis B surface antigenHCG Polyclonal IHC Human chorionic gonadotropin; germ cell tumorsHCL DBA.44 IHC Hairy cell leukemia, other B-cells (marginal zone)Hemoglobin A (Hgb) EPR3608 IHC Human hemoglobins A, A2, FHepatocyte OCH1E5 IHC Specific for normal and neoplastic hepatocytesHer2neu/c-erb-2 4B5 IHC C-erb-2 oncoproteinHHV8 13B10 IHC Human herpesvirus 8, Kaposi’s sarcoma,, primary effusion lymphomaHLA-DR LN3 IHC B-cells, activated T-cells, monocytesHLA-DR L243 Flow MHC Class II Ag, B-cells, activated T-cells, monocytesHPAP Polyclonal IHC Human prostatic acid phosphataseHPL Polyclonal IHC Human placental lactogenHPV II Low Risk ISH PROBE ISH Human papillomavirusHPV III High Risk ISH PROBE ISH Human papillomavirusHSV I Polyclonal IHC Herpes simplex virusHSV II Polyclonal IHC Herpes simplex virusIgA Polyclonal IHC Immunoglobulin A heavy chaincIgA 14-3-26 Flow Immunoglobulin A heavy chainIgD Polyclonal IHC Immunoglobulin D heavy chainIgG Polyclonal IHC Immunoglobulin G heavy chainIgG4 MRQ-44 IHC IgG subtype, IgG4-related sclerosing diseasecIgG C3-124 Flow Immunoglobulin G heavy chainIgM Polyclonal IHC Immunoglobulin M heavy chaincIgM 145-8 Flow Immunoglobulin M heavy chainsIgM Polyclonal Flow Immunoglobulin M heavy chainInhibin R1 IHC Adrenal cortical and sex cord stromal tumorsInsulin Polyclonal IHC Islet Cell TumorKappa L1C1 IHC Immunoglobulin light chain kappaKappa-ISH ISH ISH ISH Immunoglobulin light chain kappacKappa TB28-2 Flow Kappa Ig light chain, B-cells, plasma cellssKappa Polyclonal Flow Surface Kappa Ig light chainKi-67 30-9 IHC Proliferation marker

A N T I B O D Y C L O N E F L O W / I H C D E S C R I P T I O N

A-ACT Polyclonal IHC Alpha-1-antichymotrypsin, myeloid cells, histiocytesAAT Polyclonal IHC Alpha-1-antitrypsin; hepatocellular cellsACTH Polyclonal IHC Human Adrenocorticotropic Hormone, pituitaryActin HHF-35 IHC Muscle, myofibroblastic and myeloepithelial cellsAdenovirus SPM229 IHC Adenovirus identificationAE1/AE3 AE1/AE3 IHC Pankeratin cocktail; low and high molecular weightsAFP Polyclonal IHC Alpha Fetoprotein; hepatocellular and germ cell tumorsALK-1 ALK01 IHC Anaplastic Large Cell LymphomaAmyloid A MCL IHC Reactive systemic (secondary) amyloidosisAnnexin-1 MRQ-3 IHC Hairy Cell Leukemia markerArginase-1 Polytypic IHC Hepatocytes; hepatocellular carcinomaBCA-225 CU18 IHC Breast carcinomas, other carcinomasBCL-2 124 IHC B-cell subset, follicular lymphomaBCL-2 124 Flow B-cell subset, over expressed in follicular lymphomaBCL-6 GI191E/A8 IHC Follicle center B-cellsBerEP4 BerEP4 IHC Epithelial antigen, adenocarcinoma subsetBeta-Catenin 14 IHC Colon, breast, other GI tumorsBF-1 8A3 IHC T-cell receptor beta F1BOB-1 MRQ-35 IHC B-cell transcription factorCA15.3 DF3 IHC Adenocarcinoma, subsetCA19.9 121SLE IHC GI, ovary, lung tumorsCA125 OC125 IHC Ovarian, breast, othersCalcitonin Polyclonal IHC Thyroid, medullary carcinomaCaldesmon E89 IHC Smooth muscle and non-muscle contractionCalponin EP798Y IHC Myoepithelial and myofibroblastic cellsCalretinin SP65 IHC Mesothelial cellsCAM 5.2 5D3 IHC CK8/18, Low molecular weight keratinsCarbonic Anhydrase AB15086 IHC Renal Cell CarcinomaCD1a MTB1 IHC Cortical thymocytesCD2 MRQ-11 IHC Thymic and peripheral T-cells, NK cellsCD2 S5.2 Flow Thymic and peripheral T-cells, NK cellsCD3 2GV6 IHC Pan T-cellsCD3 SK7 Flow Pan T-cellsCD4 SP35 IHC Helper T-cells, thymocyte subset, monocytesCD4 SK3 Flow Helper T-cells, thymocyte subset, monocytesCD5 SP19 IHC Pan T-cells, B-cell subset thymic carcinomaCD5 L17F12 Flow Pan T-cells, mature B-cell subset (B1a cells)CD7 MRQ-12 IHC Pan T-cells, NK cellsCD7 M-T701 Flow Thymic and peripheral T-cells, NK cellsCD8 SP57 IHC Suppressor/cytotoxic T-cells; splenic littoral cellsCD8 SK1 Flow Suppressor T-cells, NK cells, thymocyte subsetCD9 M-L13 Flow Tetraspan protein, B-cell differentiationCD10 SP67 IHC Follicle center B-cells, endometrial stromal and myoepithelial cells, CALLACD10 HI10a Flow Follicle center B-cells, CALLA, myeloid subsetCD11b D12 Flow Monocytes/macrophages, dendritic, granulocytes, NK cells, myeloid

differentiationCD11c S-HCL-3 Flow Monocytes, myeloid subset, hairy cell leukemiaCD13 WM15 Flow Myeloid cells, monocytesCD14 MO-P9 Flow Mature monocytesCD15 MMA IHC Epithelial, myeloid and Reed-Sternberg cellsCD15 MMA Flow Neutrophils and eosinophilsCD16 NKP15 Flow Granulocytes, NK cellsCD19 SJ25C1 Flow Pan B-cellsCD20 L26 IHC Pan B-cell antigenCD20 L27 Flow Pan B-cellsCD21 2G9 IHC Follicular dendritic cells, C3d Receptor, B-cell subsetCD22 S-HCL-1 Flow Pan B-cellsCD23 SP23 IHC B-cell subset, CLL/SLL, follicular dendritic meshworkCD23 EBVCS-5 Flow Mature B-cells, CLLCD25 4C9 IHC TAC, Activated T and B-cells, hairy cell leukemiaCD25 2A3 Flow Activated T and B-cells, hairy cell leukemiaCD30 Ber-H2 IHC Activation Antigen; Reed-Sternberg cells, ALCL (Ki-1)CD31 JC70 IHC Endothelial cellsCD33 P67.6 Flow Myeloid cells, monocytesCD33 WM-54 IHC CD33-positive myeloid cellsCD34 QBend/10 IHC Endothelial and stem cells, GIST, BlastsCD34 My10 Flow Precursor cellsCD35 RLB25 IHC Follicular Dendritic CellsCD38 HB-7 Flow Activated T, B, myeloid cells, B-cell subsetCD41 5B12 Flow Glycoprotein IIb/IIIa complexCD41a H1p8 Flow Fibrinogen receptor, von Willebrand factor (vWf), platelets and

megakaryocytesCD43 L60 IHC T-cells, myeloid cells, B-cell subsetCD43 1G10 Flow T-cells, myeloid cells, B-cell subsetCD44 MRQ-13 IHC Intercellular adhesion molecule, urothelial carcinomaCD45 RP2/18 IHC Leukocyte common antigenCD45 2D1 Flow Leukocyte common antigenCD45R MB1 IHC Pan B-cell antigen (4KB5)CD45RA L48 Flow Resting/naive T-cellsCD45RO UCHL1 IHC T-cells, macrophages, granulocytic precursorsCD45RO UCHL-1 Flow Activated/memory T-cellsCD52 097 Flow Lymphocytes, monocytes, Campath® antigenCD55 67-CN-L063 Flow Decay Accelerating Factor, Leukocytes, Erythrocytes, PNHCD56 123C3.D5 IHC N-CAM; neuroendocrine marker, NK cellsCD56/NCAM 16.2 Flow T-cell subset, NK cellsCD57 NK-1 IHC Neuroendocrine marker, NK cellsCD57 HNK-1 Flow T-cell subset, NK cellsCD59 MEM-43 Flow Reactive Lysis Inhibitor, Leukocytes, Erythrocytes, PNHCD61 2F2 IHC Megakaryocytes and plateletsCD61 RUU-PL7F-12 Flow Megakaryocytes, plateletsCD64 10.1 Flow Monocytes, myeloid subsetCD68 KP-1 IHC Macrophages, monocytesCD71 L02-1 Flow Transferrin receptor B l u e t e x t = F l o w C y t o m e t r y M a r k e r s

A N T I B O D Y C L O N E F L O W / I H C D E S C R I P T I O N A N T I B O D Y C L O N E F L O W / I H C D E S C R I P T I O N