ANNEXURE 15 CHOICE BASED CREDIT SYSTEM STRUCTURE …nmssvnc.edu.in/biochemistry/uploadsyllabus/fae075cf24a1eadbb19f… · B.Sc BIOCHEMISTRY Sem Part Course Subject Hrs. 6th Hr. Cr

528

ANNEXURE – 15

CHOICE BASED CREDIT SYSTEM – STRUCTURE

FROM THE ACADEMIC YEAR 2014–15

B.Sc BIOCHEMISTRY

SEM Part – I Part – II Part – III Part – IV

Part – V

(6th Hr)

ACC

(6th Hr) SLC

I

Sem.

I

Lang

(6)

II Lang

(6)

Core

(4)

Core

(4)

Core Lab

(2)

Allied Che.

(4)

Allied Che.Lab

(2)

SBE

(2) –

Total

(30)

NCC/NSS/PED.

(3)

Com.Eng

(2)

Comp.Lit

(1) – –

II

Sem.

I

Lang

(6)

II

Lang

(6)

Core

(3)

Core

(4)

Core

Lab

(2)

Allied

Che.

(4)

Allied

Che.Lab

(2)

SBE

(2)

Elec.

EVS

(1)

Total

(30)

NCC/NSS/PED.

(3)

Com.Eng

(2)

Comp.Lit

(1) –

Law

&

Society

III

Sem.

I

Lang

(6)

II Lang

(6)

Core

(6)

Core Lab

(2)

Allied Bio.

(4)

Allied Bio.Lab

(2)

- NME

(2)

SBE

(2)

Total

(30)

NCC/NSS/PED.

(3)

Com.Eng

(2)

Comp.Lit

(1) – Human Rights

IV

Sem.

I

Lang (6)

II

Lang (6)

Core

(6)

Core

Lab (2)

Allied

Bio. (4)

Allied

Bio.Lab (2)

- NME

(2)

SBE

(2)

Total

(30)

NCC/NSS/PED.

(3)

Com.Eng

(2)

Comp.Lit

(1) –

Food Science

V

Sem.

Core

(6)

Core

(5)

Core

(5)

Core

(5)

Elec.I

(6) - -

SBE

(2)

Elec. W.S.

(1)

Total

(30) –

Com.Eng

(2)

Comp.Lit

(1)

Skill Devt – Career Guidance

(3)

Medical

Pharmacology

VI Sem.

Core (4)

Core (4)

Core

Lab

(3)

Core

Lab

(3)

Elec-II. (6)

Elec.III

Project

(6)

SBE (2)

Elec.

VBE

(2)

Total (30)

– Com.Eng

(2) Comp.Lit

(1)

Skill Devt –

Career Guidance

(3)

––

Total 180 Hrs

I Language – Tamil

II Language – English

SBE – Skill – Based Electives

SLC – Self – Learning Course

EVS – Environmental Studies

W.S. – Women Studies

529

CHOICE BASED CREDIT SYSTEM – STRUCTURE

FOR THOSE WHO HAVE JOINED FROM THE ACADEMIC YEAR 2014–15 ONWARDS

B.Sc BIOCHEMISTRY

Sem

Part

Course Subject Hrs. 6th

Hr. Cr.

Adl.

Cr.

Exam

(Hrs)

Marks Allotted

Int. Ext.

I

I Lang. – I Tamil – I 6 3 3 25 75

II Lang. – II General English – I 6 3 3 25 75

III

Core Fundamentals of

Biochemistry 4 4 3 25 75

Core Biomolecules 4 4 3 25 75

Core Lab Lab in Qualitative Analysis

and Enzyme Kinetics 2 – – – –

Allied

Che. General Chemistry – I 4 4 3 25 75

Allied

Che. Lab Volumetric Analysis Lab – II 2 – – – –

IV SBE - I Human Physiology 2 2 2 25 75

V Extension

activities NSS / NCC / PED 3 – – –

Additional

Courses

Communicative English–I 2 – – –

Computer Literacy 1 – – –

II

I Lang. – I Tamil – II 6 3 3 25 75

II Lang. – II General English – II 6 3 3 25 75

III

Core Enzymes 3 3 3 25 75

Core Metabolism – I 4 4 3 25 75

Core Lab Lab in Qualitative Analysis

and Enzyme Kinetics 2 2 3 40 60

Allied

Che. General Chemistry – II 4 4 3 25 75

Allied

Che. Lab

Volumetric Analysis

Lab – II 2 2 3 40 60

IV SBE - II Viriology 2 2 2 25 75

EVS Environmental Studies 1 1 2 – 100

V Extension

activities NSS / NCC / PED 3 – – –

Additional

Courses

Communicative English–I 2 1 3 25 75


S L C Law and Society 3 3 – 100

530

Sem

Part

Course Subject Hrs.

6th

Hr. Cr.

Adl.

Cr.

Exam

(Hrs)

Marks Allotted

Int. Ext.

III

I Lang. – I Tamil – III 6 3 3 25 75

II Lang. – II General English – III 6 3 3 25 75

III

Core Metabolism – II 6 5 3 25 75

Core Lab Lab in Quantitative Analysis

of Bimolecules 2 – –

– –

Allied Bio. Cytology 4 4 3 25 75

Allied Bio.

Lab

Lab in Cytology and Human

Genetics 2 – –

– –

IV

NME - I Environmental Pollution –

Health and Toxicology 2 2 2 25 75

SBE - III Genetic Engineering 2 2 2 25 75

V Extension

activities NSS / NCC / PED 3 –

– –

Additional

Courses

Communicative English–II 2 – – –


SLC Human Rights 3 3 – 100

IV

I Lang. – I Tamil – IV 6 3 3 25 75

II Lang. – II General English – IV 6 3 3 25 75

III

Core Biophysical and Biochemical

Techniques 6 5 3

25 75

Core Lab Lab in Quantitative Analysis

of Bimolecules 2 2 3

40 60

Allied Bio. Human Genetics 4 4 3 25 75

Allied Bio.

Lab

Lab in Cytology and Human

Genetics 2 2 3

40 60

IV

NME - II Medical Biochemistry 2 2 2 25 75

SBE- IV Biotechnology 2 2 2 25 75

V Extension

activities NSS / NCC* / PED* 3 1 3

25

*40

75

*60

Additional

Courses

Communicative English–II 2 1 3 25 75


SLC Food Science 4 3 – 100

531

Sem

Part

Course Subject Hrs.

6th

Hr. Cr.

Adl.

Cr.

Exam

(Hrs)

Marks

Allotted

Int. Ext.

V

III

Core Clinical Biochemistry – I 6 5 3 25 75

Core Molecular Biology 5 4 3 25 75

Core Microbiology 5 4 3 25 75

Core Immunochemistry 5 4 3 25 75

Elec.- I Biochem. paper (1) and (2)

Any one from

6 5 – 40 [*30:@10]

60 [*50:@10

]

IV SBE - V Medical Lab Technology 2 2 2 25 75

WS Women Studies 1 1 2 – 100

Additional Courses

Communicative English–III 2 – – –


Skill Development – Career

Guidance 3 – – –

SLC Medical Pharmacology 4 3 - 100

VI

III

Core Clinical Biochemistry – II 4 4 3 25 75

Core Plant Biochemistry 4 4 3 25 75

Core Lab Lab in Micro Biology and

Molecular Biology 3 3 3 40 60

Core Lab Lab in Clinical Biochemistry 3 3 3 40 60

Elect. - II Biochem. paper (1) and (2)

Any one from

6 5 3 25 75

Elect.- III

Project

*Report;@Viva 6 5 3 25 75

VI SBE - VI Bio physics 2 2 2 25 75

VBE Value Based Education 2 2 2 – 100

Additional

Courses

Communicative English–III 2 1 3 25 75

Computer Literacy 1 1 3 – 100

Skill Development – Career

Guidance 3 2 3 – 100

TOTAL 180 36 140 20

*Elective I and II: Each Elective paper has two choices, select any one from.

1.1. Genomics

1.2. Biostatistics

2.1. Endocrinology

2.2. Bioinformatics

532

ALLIED – BIOLOGY FOR BIOCHEMISTRY

Sem Title of the Paper

Hrs.

Cr. Exam

(Hrs)

Marks Allotted

Int. Ext.

III Cytology 4 4 3 25 75

IV Human Genetics 4 4 3 25 75

IV Lab in Cytology and Human

Genetics 2 2 3 40 60

V Biostatistics 3 3 3 25 75

VI Human Physiology 3 3 3 25 75

VI Lab in Biostatistics and Human Physiology

2 2 3 40 60

533

B.Sc BIOCHEMISTRY: Those Who Have Joined From The

Academic Year 2014–15 Onwards Under CBCS System

Core Subject METABOLISM – II Code: 14283301

SEMESTER III

6 Hrs/Week

Credits 5

Objectives:

To educate students in the areas of primary and secondary

metabolism.

To gain new information about organizational metabolism.

UNIT – I: [18 Hrs]

Nucleic acid Metabolism – Purine and Pyrimidine bases –

Biosynthesis of Purines and Pyrimidines – biosynthesis of DNA and

RNA.

UNIT – II: [18 Hrs]

Mineral Metabolism – a brief account, Blood cells, Blood groups

– Blood coagulation – Blood transfusion, Compatibility.

UNIT – III: [18 Hrs]

Hormones – definition – classification – mechanisms of action of

hormones and signal transduction.

UNIT – IV: [18 Hrs]

Function of the Pancreas, thyroid and adrenal glands, Steroid

metabolism Biological effects of androgens and estrogens.

UNIT – V: [18 Hrs]

Neurochemistry – Synapse – Neuro transmitters, receptors.

TEXT BOOK:

01. Robert K. Murray, Peter A. Meyes, Victor W. Roadwell, Harper’s

illustrated Biochemistry, 26th Edition, McGraw – Hill, Bosten,

2003.

REFERENCES:

01. Albert L., Lehinger, Principles of Biochemistry, CBS publishers

and Distributors.2nd edition, New Delhi, 2003.

02. Donald Voet and Judith Voet, Biochemistry, Wiley International

2nd Edition, New York, 2006.

03. Gerald carp, Cell and Molecular Biology, 3rd edition, John Wiley

and Sons. Inc, New York, 2003.

04. Lubert Stryer et at, Biochemistry, 7th edition, W.H.Freeman and

Company, New York, 2012.

534

Part – IV ENVIRONMENTAL POLLUTION – HEALTH AND TOXICOLOGY Non-Major Electives SEMESTER III Code: 14463328

2 Hrs/Week

Credits 2

Objectives:

To assess environmental factors that influence human health and

quality of life, and seeks to prevent adverse effects on human health

and ecological systems.

UNIT – I: [6 Hrs]

Introduction – Types of Pollution, Sources of Pollution, Persisted

Organic Pollutants, Environmental mobility of Pollutants.

Air Pollution – Classification and properties of air pollutants,

behaviour and fate of air pollutants – Wet precipitation, dry deposition,

Interaction at the earth’s surface, Nature and development of acid rain

- Acid rain and aquatic terrestrial and the Built environment, Effects

of air pollution, Indoor air pollution, Prevention and control of air

pollution.


Water and Land Pollution – Origin of waste water – Domestic

Water Pollution, Industrial Water Pollution, Oil Pollution – Toxic Water

Pollutants and their effects – Minamata disease, Pollution problems of

leather industries.

Noise Pollution – Sources and effects, Radio active Pollution –

Natural and man made incidents of radioactive pollution – Hiroshima

Catastrophe, Chernobyl accident – Radioactive contamination of River

Periyar.


Environment and Community Health: Epidemiologic concepts of

disease – Malaria – Effects, Environment factors, agent factors, host

factors, vector of malaria – Mode of transmission, Malaria control

strategies – Biological Control.

Tuberculosis – Agent factors, host factors, social factors, mode of

transmission, control of tuberculosis.


Occupational hazards – Physical, Chemical, Biological,

Psychosocial hazards. Asbestosis, lead poisoning, Occupational

cancer.

UNIT – V: [6 Hrs]

Toxicology – Environmental toxicology – Exposure,

bioaccumulation, biomagnifications, Portal entry of a toxin,

Metabolism of toxin, Nature of toxin effects in human – Heavy metal

toxicity – Arsenic, Cadmium, Alcohol toxicity, Pesticides toxicity.

535

TEXT BOOK: 01. Rana S.V.S., Environmental Pollution-Health and Toxicology,

Narosa Publishing House Private Limited, 1st Reprint, 2007. REFERENCE:

01. Sharma B.K., Environmental Chemistry,1st edition, Goel Publishing House, Meerut. 1992

Part – IV GENETIC ENGINEERING Code: 14443328

Skill Based Electives SEMESTER III

2 Hrs/Week

Credits 2

Objectives:

To understand invitees DNA technologis that are used to isolate genes

from an organisims manipulate them into another cell systems for

specific genetic trait.

UNIT – I: [6 Hrs]

DNA Cloning: Restriction enzymes, complementary DNA,

cloning vectors, – pBR 322 cosmids, Plasmids, Ligation of sticky ends,

blunt end ligation, homopolymer tailing. Techniques involved in

transfer of genes in E coli.


Detection and characterization of recombinants – Gene markers,

Plus and Minus Screening, Immunochemical methods, hybridization

methods.


Gene Manipulation in Plants: Transgenic plants, Gene transfer

through Agrobacterium tumefaciens, Herbicide resistant plants, virus

resistant plants, pest resistant plants.


Transgenic animals - methods, gene therapy– gene knock out.

UNIT – V: [6 Hrs]

Human Genome project, DNA micro array, DNA finger printing –

PCR, RFLP, RAPD.

TEXT BOOKS:

01. Bernard R.Glick, Molecular Biotechnology – Principles and Applications of Recombinant DNA, 2nd edition,1998 ASM Press, Washington, D C.

02. James D.Watson Michacl Gilman, Recombinant DNA, 2nd Edition,1928 Scientific American Books, New York.

03. Old and Primrose S.B., Principles of Gene Maniputiulation, 2nd

Edition,1994, Blackwell Scientific Publication, London.

REFERENCES:

01. Brown C.M., Campbell I., Priest F.G., Introduction to Bio

Technology, Blackwell Scientific Publications, London, 1998.

02. Pamela Peters, Biotechnology, A Guide to genetic engineering,

WCB McGraw – Hill, Boston, 1988.

536

Core Subject BIOPHYSICAL AND BIOCHEMICAL TECHNIQUES

SEMESTER IV Code: 14283401

6 Hrs/Week

Credits 5

Objectives:

To understand the basic principles of techniques that are used

routinely in modern biochemistry and molecular biology.


Chromatography: Column, Paper and Thin layer

chromatography, Adsorption, Partition, Ion exchange, Gas

Chromatography and HPLC. Gel filtration and Dialysis.


Electrophoresis – Principles – Instrumentation and Application –

Agarose, SDS-PAGE; Principles and application of PCR.


Centrifugation – Theory, relation between rpm and g –

Differential centrifugation, density gradient – Different types of

centrifuges, Measurement of Gases – Manometry.


Colorimetry: Light spectrums and its wavelength regions –

complementary colours. Molar Extinction co-efficient. Beer Lambert’s

law and its application.


Radioisotopes in Biochemistry, Radioactivity, Elementary Units,

Deduction of radioactivity – Autoradiography, fluorography, isotopic

trace technique, Isotope dilution method

TEXT BOOK: 01. Upadhay, Upadhay, Nath, 3rdedition,1 998, Biophysical

Chemistry, Principles and Techniques, Himalaya Publishing House, Bombay.

REFERENCE:

01. Wilson and Walker, Practical Biochemistry, 5th Edition, 1994, Principles and Techniques Cambridge low-price Editions,

Cambridge University Press.

Core Lab LAB IN QUANTITATIVE ANALYSIS OF BIMOLECULES SEMESTER III & IV Code: 14283402

2 Hrs/Week

Credits 2

Objectives:

To gain knowledge about the quantitative analysis of Biomolecules and

their

01. Estimation of glucose by Phenol Sulphuric acid Method

02. Estimation of proteins by Lowry’s method.

537

03. Estimation of fructose by Seliwanoff’s methods.

04. Estimation of pentose by Bials methods.

05. Estimation of Ascorbic acid (Colorimetric/Titrimetry)

06. Estimation of reducing sugar in fruits.

07. Estimation of Lactose in milk.

08. Estimation of DNA.

09. Estimation of RNA.

10. Separation of amino acids by Paper Chromatography.

11. Separation of amino acids by TLC.

12. Separation of proteins by SDS-PAGE.

13. Identification of Nucleic acids by Agarose gel eletrophoresis.

14. Protein purification – Protein precipitation, Dilaysis, Column

Chromatography (Demonstration Only)

REFERENCES:

01. Palanivelu P., Laboratory Manual for Analytical Biochemistry

and Separation Techniques ,4th edition 2009.

02. Pattabiraman, Lab Manual in Biochemistry,3rd edition,1998, All

India Publishers & Distributor, Chennai.

03. Sadashivam, Biochemical Mehods, 1996,New Age International

Publishers, New Delhi,

04. Varley, Practical Clinical Biochemistry, 6th Edition,1988, CBS

Publishers, New Delhi.

Part – IV MEDICAL BIOCHEMISTRY Code: 14463428

Non-Major Electives SEMESTER IV 2 Hrs/Week

Credits 2 Objectives:

To develop and integrates a basic research program with clinical

practice in a field of biochemical interest, and maintains an active

role as a teacher of clinically applied Bio chemistry.

UNIT – I: [6 Hrs]

Basic Medical Biochemistry: Units of measurement; Weight,

Volume, Temperature and Viscosity, Concentration; Normality,

Molarity, Molality and PPM. Biochemical tech; pH, Buffer, Dialyais,

Osmosis.


Chemistry of Biomolecules: The cell, Carbohydrates, Proteins,

Lipids and Nucleic Acids, Chemistry of Blood – SGOT and SGPT,

Biological Oxidation, Vitamins, Immunoglobulins and Prostaglandins.


Function Tests: Renal, Liver, test for pregnancy and ELISA.


Disease and Disorders: AIDS, Diabetes, Cancer, Anaemia,

Tuberculosis, Fever and water borne diseases. [cholera]

538

Heart Diseases: (Atherosclerosis, Pulmonary Embolism and

Myocardial infarctions).

UNIT – V: [6 Hrs]

Liver Diseases: (Jaundice and alcoholic cirrhosis).

Kidney Diseases: (Glomerular Nephritis, Acute and Chronic

Renal Failure).

Brain Disorder-Alzheimier’s Disesase.

TEXT BOOKS:

01. Chatterjee M.N., Text Book of Medical Biochemistry, 6th Edition,

2005, Jaypere Brother’s.

02. Ramakrishnan S., Text Book of Medical Biochemistry, 2nd

Edition, 1998, Orient Longman.

REFERENCES:

01. Alan H.Gowenlock, Varleys Practical Clinical Biochemistry, 6th

Edition, 2002, CBS Publisher, New Delhi.

02. Harrison’s, Principles of Internal Medicine, Vol. I and II,

McGraw – Hill.16th edition, 2005.

Part – IV BIOTECHNOLOGY Code: 14443428

Skill Based Electives SEMESTER IV

2 Hrs/Week

Credits 2

Objectives:

To update the application of biotechnology in various fields.

UNIT – I: [6 Hrs]

Introduction to Biotechnology – Restriction enzymes and DNA

ligases, Introduction to gene cloning – types of cloning vectors –

plasmid, phagemid, cosmid, M13 phage, BAI, YAC.


Plant Biotechnology: Agrobacterium mediated gene transfer,

transgenic plants and its applications, crop improvement.


Animal Biotechnology: Viral vector system – Bacterio viral vector,

methods for producing transgenic animal – Micro injection – Electro

poration – gene gun method – Invitro fertilization and embryo transfer.

Application of transgenic animal.


Microbial Biotechnology: Basic principles of microbial growth –

types – design and operation of fermentors, microbial degradation of

oil spills, Biodegradable plastics.

UNIT – V: [6 Hrs]

Production of recombinant proteins: insulin, interferon and

vaccines, treatment of various human disorders, gene therapy.

539

TEXT BOOK: 01.Bernard R.Glick, and Jack J.Pasternek, Molecular

Biotechnology, 2nd Edition, ASM Press, Washington, 1998. 02.James D.Watson Michacl Gilman, Recombinant DNA, 2nd

Edition,1928, Scientific American Books, New York. REFERENCE:

01.Brown C.M., Campbell I., Priest F.G., Introduction to Bio

Technology, 1st edition, 1988, Blackwell Scientific Publications,

London.

Self Learning Course-Major FOOD SCIENCE Code: 14803428

SEMESTER IV

Addl. Credits 4

Objectives:

To understand the Nutritive values of Bio molecules, planning of

balanced diets and about preservation methods of foods and also about

food laws.

UNIT – I:

Carbohydrate – Function, Digestion and Absorption, Regulation

of Blood Sugar, Requirements.

Lipids – Chemistry, Properties, Functions, EFA, Digestion and

Absorption, deficiency, Hypercholesterolemia and coronary heart

disease.

Proteins – Digestion and Absorption, Functions, Nutritive value

of proteins, Evaluation of the nutritive value of proteins, Protein

Calorie Malnutrition in Children.

UNIT – II:

Energy units, determination of energy value of foods,

Physiological energy value of foods, Basal metalosim – Determination,

Standards, Factors affecting BMR, Specific Dynamic Action.

Effect of cooking and heat processing on the nutritive value of

foods – Vitamins, Minerals, Cereals, Legumes, Fats and Oils, Milk and

Milk Products.

UNIT – III:

Food groups and planning of balanced diets – Classification of

foods – Functional classification of food, 7 food group plan, 11 food

group plan.

Infant nutrition and infant food, modification of animal milk for

infant feeding, processed infant foods, supplementary food.

Nutrition of school children, adolescents, pregnant and lactating

mothers.

UNIT – IV:

Food Quality and Food Adulteration.

540

Sensory evaluation – Sensory characteristics of food, conducting

sensory, reasons for testing food quality, types of tests – Difference

tests, rating tests, sensitivity test, descriptive test.

Food adulteration – Definition, Types, Microbial Contamination,

Metallic Contamination, Packaging Hazards, food law and standards.

Food additive and its ill effects.

UNIT – V:

Food Preservation and Future Foods.

Methods of food preservation - by low temperature, by high

temperature, by preservatives, by high osmotic pressure, by high salt

concentration, by dehydration.

Biotechnology in food, Biofortification, Nutraceuticals, Organic

foods, Low cost nutrient supplement, space food.

TEXT BOOK:

01. Dr. M.Swaminathan, Hand Book of Food and Nutrition, 5th

Edition, 2006, Bangalore Press.

REFERENCE:

01. Srilakshmi B., Food Science, 3rd Edition, 2006, New Age

International Publisher.

Allied Biology CYTOLOGY Code: 14283321 [For Biochemistry Major Students]

SEMESTER III

4 Hrs/Week Credits 4 Objectives:

Understanding the essential principles, process of cell biology.

To know dynamic nature of the cell, its capacity of growth and

division.

To acquire informations about cells and how they functions.

UNIT – I: [9 Hrs]

Cell Structure – Prokaryotic and Eukaryotic (Plant and Animal

Cells – Structural Features – A Brief Account)

Plasma Membrane – Chemistry and Ultra Structure – Fluid

Mosaic Model, Functions to be dealt Briefly.

Protoplasm:

Chemistry and Organisation.


Membrane systems in Eukaryotes:

Endoplasmic Reticulum and Golgi Complex, Structure and

Function to be dealt Briefly.

Nucleus:

Nuclear Envelope Structure, Chromosomes – Kinds, Structure.

541


Organelles in Eukaryotes:

Plastids – Kinds, Occurrence in Plants, Chloroplast, Ultra

Structure, Functions, Mechanism of Photosynthesis – Brief Account.

Ultra Structure and Functions (Brief Account) Mitochondria,

lysosomes and Ribosomes.


Cell Cycle – Mitosis and Meiosis, Cell Growth Normal and

Cancerous.

UNIT – V: [9 Hrs]

Histochemical Staining

a. Proteins, (Mercuric Bromophenol Blue Method)

b. Lipids and Lipoproteins – Sudan Black ‘B’ Methods

c. Carbohydrates.

TEXT BOOK:

01. Verma P.S., and Agarwal V.K., Textbook of Cytology, S.Chand and Co., New Delhi,1st edition,1995.

REFERENCES: 01.De Robertis E.D.P., F.A.Saez and De Rovertis E.M.F., Cell and

Biology,8th edition,1998,B.I. Waverly Private Limited, New Delhi,

. Allied Biology HUMAN GENETICS Code: 14283421

[Biochemistry Major Students] 4 Hrs/Week

SEMESTER IV Credits 4

Objectives:

The bio chemistry of the nucleic acid lies at the heart of genetics

molecular anatomy of cells used to analyse evolutionary relationships

and to refine evolutionary theory.


Transmission Genetics: Mendelian Inheritance – Mendels work,

method experiments observation and results. Terminology – Mendels

laws. Non allelic gene interactions. Multiple alleles – Blood group

inheritance in man.


Sex determination and differentiation: The different levels of

sexual identity, sexual development. Sex chromosomes – SRY gene

action begins sexual differentiation. The phenotype forms sex linked

recessive inheritance, sex linked dominant inheritance – Sex limited

traits, sex influenced traits, genomic imprinting.


Cytogenetics: Portrait of a chromosome, visualizing chromosome

obtaining cells for chromosome study, preparing cells for chromosome

observation. Abnormal chromosome number – Polyploidy –

542

Aneuploidy, sex chromosome aneuploidy abnormal chromosome

structure – Deletions, duplication, Inversions and Translocations.


Population Genetics: A population view of the gene – Gene pool,

gene flow, Allele frequency and genotype frequency. Hardy – Weinberg

equilibrium – An over view. Demonstrating H-W equilibrium

applications and factors affecting H-W equilibrium.


Simple Mendelian Traits in human – modes of inheritance;

pedigree charts – symbols, lines and numbers. Twins – Types of twins.

Inborn errors of metabolism – PKU and Albinism.

TEXT BOOK:

01. Ricki Lewis, Human Genetics-Concepts and Applications, 3rd

Edition, 1999, WCB McGraw – Hill Publications.

REFERENCE:

01. Robert J.Brooker, Genetics Analysis and Principles, 1st Edition,

1999, Addision Wesley Menlo Park.

Allied Biology Lab LAB IN CYTOLOGY AND HUMAN GENETICS

[Biochemistry Major Students] 2 Hrs/Week

SEMESTER III & IV Credits 2

Code: 14283423

Objectives: To learn the methods of Preperation, observation of cellular structures.

To verify the methods of inheritance by simple Experiments.

1. Demonstration of Histochemical Staining Method.

2. Study of Mitosis – Smear method of Allium Cepa Root.

3. Study of Human Finger Print.

4. Study of Human Chromosome.

5. Survey of single mendelian traits in Man.

6. Study of Mendel’s Law.

7. Inheritance of Physical Characters in Man.

8. Verification of Hardy – Weinberg Law.

9. Pedigree Analysis.

10. Different Types of Muscles (Spotter only).

11. Aneuploidy in human sex chromosomes.

REFERENCE:

01. Peter Abram Off and Robert G.Thomson, An Experimental

Approach to Biology, 2nd Edition W.H. Freeman and Company

Sanfrancisco.

543

B.Sc BIOCHEMISTRY: Those who have joined from the

academic year 2014-15 onwards under CBCS System

EVALUATION PATTERN

Internal : 25 Marks External : 75 Marks

INTERNAL:

Test – 20 (average of the better two of the three tests conducted)

Assignment – 5

Question Paper Pattern:

INTERNAL EXTERNAL

Part – A : 6 1 = 6

(Multiple Choice)

Part – B : 2 7 = 14

(Either /Or)

Part – C : 2/3 10= 20

*40

Part – A :10 1 = 10

(Multiple Choice)

Part – B : 5 7 = 35

(Either /Or)

Part – C : 3/510 = 30

75

* Internal test mark 40 will be converted to 20.

SBE & NME

INTERNAL EXTERNAL

Part – A : 3 1 = 3

(Multiple Choice)

Part – B : 1 7 = 7

(Either /Or)

Part – C : 1/2 10= 10

20

Part – A :15 1 = 15

(Multiple Choice)

Part – B : 3/5 10 = 30

Part – C : 2/415 = 30

75

The Assignment Component of any one of the subjects (except

Non-Major Electives and other Department Papers) in the III and IV

Semesters in UG COURSES (as decided by the Head of the Department

on Rotation Basis) should be in the form of REPORT (as per the

guidelines) on the HANDS ON EXPERIENCE GAINED by the students

from their:

Part-time job (or)

Self-Employment (or)

Making of Hand made Products (or)

Survey on Marketing of goods and services (or)

Maintenance and Servicing of Equipments (or)

How things Work (or)

Working Principles of Toys/gadgets…. Models (or)

Making of working Models using some Concepts

Students should maintain a work diary which should be

monitored by the course teacher guided by a Monitoring Committee

of the concerned department.

Documents

ANNEXURE 15 CHOICE BASED CREDIT SYSTEM STRUCTURE …nmssvnc.edu.in/biochemistry/uploadsyllabus/fae075cf24a1eadbb19f… · B.Sc BIOCHEMISTRY Sem Part Course Subject Hrs. 6th Hr. Cr