Angiographic Features of Angiographic Features of Atherosclerotic Atherosclerotic

Superficial Femoral Superficial Femoral Artery Disease in Artery Disease in

Diabetics and Non-Diabetics and Non-diabetics Presenting diabetics Presenting

with Claudicationwith Claudication

Atif Mohammad, MDResearch Fellow

VA North Texas Health Care System

UT Southwestern Medical Center

Dallas,TX

On behalf of the investigators:

INVESTIGATORSINVESTIGATORS

Atif Mohammad, MD*†

Avantika Banerjee*

Omar Hadidi, MD†

Gene Pershwitz, MD*

Mirza Baig, MD*†

Emmanouil S. Brilakis, MD, PhD*†

*VA North Texas Health Care System, Dallas, TX; †University of Texas Southwestern Medical Center, Dallas, TX; Acknowledgements: Dallas VA Research Corporation

BACKGROUND & METHODBACKGROUND & METHOD

Though clinical outcomes following percutaneous revascularization of superficial femoral artery (SFA) varies between diabetics (DM) and non-diabetics, angiographic differences of their SFA disease has never been systemically analyzed

We conducted blinded angiographic analysis of peripheral angiograms in 117 consecutive patients (79 DM and 38 non-DM) between January 2009 - January 2011, presenting to Veterans Affairs Haelth Care System (Veterans Integrated Service Network or VISN 17) with Rutherford category 3 claudication

METHOD: ANGIOGRAPHIC METHOD: ANGIOGRAPHIC ANALYSIS ANALYSIS

BOLLINGER SCOREBOLLINGER SCORE

RESULTS: Mean Bollinger RESULTS: Mean Bollinger ScoresScores

p=0.03

Non-DM DM

RESULTS:RESULTS:

SFA: superficial femoral artery

RESULTS: Angiographic Distribution RESULTS: Angiographic Distribution of SFA in Diabetics & Non-Diabeticsof SFA in Diabetics & Non-Diabetics

n=78

n=39

SFA: superficial femoral artery

RESULTS: Lesion Flow & Stenosis Characteristics RESULTS: Lesion Flow & Stenosis Characteristics in Diabetics & Non-Diabeticsin Diabetics & Non-Diabetics

RESULTS: Lesion Characteristics & RESULTS: Lesion Characteristics & Revascularization in Diabetics & Non-Revascularization in Diabetics & Non-DiabeticsDiabetics

RESULTS: Procedural RESULTS: Procedural Complications & Outcomes in Complications & Outcomes in Diabetics & Non-DiabeticsDiabetics & Non-Diabetics

CONCLUSIONS:CONCLUSIONS:These results indicate the greater

severity of SFA disease in patients with diabetes mellitus, increased need for stenting & lower 12 month patency

Our findings also indicate to the need for dedicated strategies for improving outcomes in diabetics with peripheral arterial disease undergoing endovascular revascularization procedures for life-style limiting claudication

SFA: superficial femoral artery