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Aneurysm Repair Where are we now? Richard Parsons M.D. FACS

Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

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Page 1: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Aneurysm Repair Where are we now?

Richard Parsons M.D. FACS

Page 2: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Endovascular treatment of aortic disease

Page 3: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Anatomy

Page 4: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Indications for repair of AAA

• Size > than 5cm

• Expansion greater than 0.2-.4 cm/year

• Symptomatic aneurysm

• Rupture

Page 5: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Endovascular stent graft repair of Abdominal Aortic Aneurysm(EVAR)

• First performed in the US in 1994

• Has become the most common way to repair AAA 90+% at Abington Hospital

• From 2014-2016 we have performed 83 EVARs

• Length of stay is usually 1 night

Page 6: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Endovascular repair of Abdominal Aortic Aneurysm

Page 7: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Technically challenging features of endovascular aneurysm repair

Inverted funnel

Page 8: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Technically challenging features of endovascular repair

Thrombus

thrombus

neck Accessory rena artery

Angulated neck

Page 9: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Complications of repair

• Renal failure

• Colonic ischemia

• Aortic rupture

• Endoleaks

Page 10: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Bowel ischemia Bowel ischemia

Colon ischemia

Renal ischemia

Page 11: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

CAUTION—Investigational device. Limited by Federal (or United States) law to investigational use.

Juxtarenal: AAA

Page 12: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Post treatment leaks

Page 13: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Endoleak classification types I-V

Page 14: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Type I endoleak

Page 15: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Type II endoleak from IMA retrograde flow

Page 16: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Thoracic aneurysm

Page 17: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Endovascular thoracic aortic aneurysm repair

Page 18: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The
Page 19: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Endovascular vs open Thoracic Aneurysm Repair

• Repair when 6cm or greater • Less painful • Shorter length of stay • Less morbidity and mortality

Page 20: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Complications of TAA repair

• Endoleak • Graft migration • Stent fracture • Delayed rupture • Infection • Paraplegia

Page 21: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Best case scenario rare ! • Left subclavian artery not involved • Does not extend below diaphragm • Spinal ischemia risk diminished

LSCA

Page 22: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Risk factors for paraplegia

• Long thoracic segment coverage

• Previous abdominal aortic repair

• Intra or postoperative hypotension

Page 23: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The
Page 24: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Mechanisms to decrease paraplegia risk

• Avoid hypotension • Stage thoracic and abdominal repair

– 3-6 months apart • CSF catheter drainage to decrease spinal cord

pressures to be below 10mm • Evoked potential monitoring using balloon

occlusion • Temporarily creating an endoleak that is later

closed

Page 25: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Thoracic dissection

Page 26: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Treatment of type B dissection

• 90 % can be treated with BP control and pain medication

• Continued pain or aortic rupture requires immediate repair

• Invasive treatment is reserved for nonperfused vascular beds

–Mesenteric –Renal –Lower extremity –Late aneurysmal degeneration

Page 27: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Treatment strategies

• Open fenestration • Endovascular fenestration • Proximal endograft placement to

open the true lumen and close the false lumen

Page 28: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Risks of treatment

• Aortic rupture • Stroke • Spinal cord ischemia( paraplegia) • Ischemia of branch vessels( renal,

mesenteric,extremeties)

Page 29: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Dissection Endovascular Stents

STABLE I Trial Enrollment • 83 pts. enrolled • US and OUS centers

CAUTION—Investigational device. Limited by Federal (or United States) law to investigational use.

Page 30: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Remodeling of the aorta after dissection flap is closed

Page 31: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Treatment of asymptomatic aortic dissection

• Prevention of late aneurysm dilatation • Aortic remodeling occurs in 90% of treated

patients • Only 70% of untreated patients remodeled

30% have aneurysmal dilatation • Unclear if treatment of all asymptomatic

dissections is justified

Page 32: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The
Page 33: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Traumatic aortic dissection

• High speed deceleration injury • The aorta is tethered at the

ligamentum arteriosum dissection occurs just distal to subclavian

• Wide mediastinum on chest X-ray • CTA confirms dissection

Page 34: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The
Page 35: Aneurysm Repair Where are we now? - Jefferson Health · 2017-04-24 · Best case scenario rare ! • Left subclavian artery not involved ... Traumatic aortic dissection ... • The

Thank you!

Richard Parsons MD