http://anapa.com

New Generation

Gas-Pressured Infusion Device

anapa & anaplus

More Convenient!

MoreAccurate!

MuchSafer!

ananpa & anaplus

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• Repetitive filling of medication by

syringe

• Difficult due to the internal pressure of

pump

No-resistance Filling

Maximizing

convenience

anapaExisting Pumps

• Long Priming time

• Long preparation time and inefficiency

World’s 1st

about 2minuts Priming

• Flow change due to the position of

Chamber

• Not optimized for treatment due to the

inaccurate flow rate

More accurate flow rate

by increased pressure

ananpa & anaplus

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1. No-resistance Filling

2. Short Priming time

4. Monitoring the injected volume accurately

5. Prevention of over-dose

6. Minimizing residual volume

3.Minimizing the change of flow rate by chamber

position

7. Minimizing the risk of contamination

ananpa & anaplus

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ananpa & anaplus

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World 1st

CO2 PressuredInfusion device

SpecialRelief Valve(R/V)for Maintaining

CO₂ gas pressure

Constant flow rate by

Glass capillary

Gas-Pressured Infusion Device

ananpa & anaplus

ananpa & anaplus

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Citric acid

3Na2CO3

SodiumCarbonate

2C6H8O7

Generation of CO2

gas

3H2O+ 3CO2↑+ 2Na3C6H5O7

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Membrane Filter

• Hydrophobic Filter : Pass gas, Keep liquid

• Generated gas passes membrane filter and moves to Chamber, pushes

Piston.

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Relief Valve(R/V)

The pressure inside Chamber is

controlled at set-value,

Extra CO₂ gas is released outside

Chamber

=> Accurate flow rate

0bar

0.1bar

0.2bar

0.3bar

0.4bar

0.5bar

0.6bar

0.7bar

0ml

1ml

2ml

3ml

4ml

0hr 8hr 16hr 24hr 32hr 40hr

Pre

ssure

[ bar

]Flo

wR

ate

[ m

l/hr

]

Time [ hr ]

2.2ml

1.8ml

48hr 56hr

ananpa & anaplus

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ModelAvg. Flow rate

(Criteria ± 15%)

Instantaneous Flow Rate (Criteria ± 50%)

Max. Flow rate Min. Flow rate Difference

anapa 0.5% (2.01ml/hr) 2.0% (2.04 ml/hr) -3.0% (1.94 ml/hr) 5%

"A" 16.5% (2.33ml/hr)50.0% (3.00 ml/hr

)6.0% (2.12 ml/hr) 44%

“B" -8.5% (1.83ml/hr)10.0% (2.20 ml/hr

)-20.0% (1.60 ml/hr) 30%

“C" -18.0% (1.23ml/hr)16.0% (1.74 ml/hr

)-29.3% (1.06 ml/hr) 45.3%

• - The average flow rate shall have a tolerance of ± 15%

compared to the nominal flow rate.

• - At least 80% of the nominal volume shall be delivered at

an instantaneous flow rate within ± 50% of the

In accordance with ISO 28620:2010_Non-electrically driven portable infusion device

ananpa & anaplus

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• Instantaneous Flow Rate both at the beginning and end of injection should be in ± 10% variation.

• The accuracy is key criteria of Infusion pump.

0bar

0.1bar

0.2bar

0.3bar

0.4bar

0.5bar

0.6bar

0.9ar∨

0ml

1ml

2ml

3ml

4ml

0hr 8hr 16hr 24hr 32hr 40hr

anapa Flow Rate (ml/hr)

Balloon Flow Rate (ml/hr)

anapa Pressure (bar)

Balloon Pressure (bar)

Pre

ssure

[ bar

]

Flo

wR

ate

[ m

l/hr

]

Time [ hr ]

2.2ml

1.8ml

48hr 56hr

+15%

-15%- 10%

+10%

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• The first internal pressure is “0” as the inside and outside of Chamber connected.

• The air inside Chamber goes outside upon filling.

• Totally different from balloon pumps which much power is required during filling procedure.

• Minimizing the preparation road and time of clinicians

ananpa & anaplus

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Fillin

g P

ressure

Balloonpumps

anapa

Filling Pressure

A : 9.28kgf

B : 9.08kgf

C : 8.04kgf

No resistance

anaplus

1.50kgf

D : 5.40kgf

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• Change on the flow rate by the position of Chamber.

ex) hanging on rack, put in pouch and wear on waist etc.

• The variation on flow rate of Balloon pumps is widely due to the low pushing pressure.

Flow change by the position of Chamber

( +100cm ) 2.626 (+100cm ) 31.3% 21.0%

( +50cm ) 2.488 ( +50cm ) 24.4% 13.6%

( 0cm ) 2.216 ( 0cm ) 10.8% 기준

( -50cm ) 2.006 ( -50cm ) 0.30% -10.5%

AverageFlow Rate

(ml/hr)

Percentage

Deviation(%)

0

1

2

3

4

0 8 16 24 32 40 48 56

유량(+100cm)

유량 0cm

유량 (+50cm)

유량(-50cm)

압력

[bar]

유량

[ml/

hr]

Balloon pumps anapa

( +100cm ) 2.03 (+100cm ) 1.5% 6.0%

( +50cm ) 1.90 ( +50cm ) -5.0% -0.5%

( 0cm ) 1.91 ( 0cm ) -4.5% 기준

( -50cm ) 1.80 ( -50cm ) -10% -5.5%

AverageFlow Rate

(ml/hr)

Percentage

Deviation(%)

0

1

2

3

4

0 8 16 24 32 40 48 56

유량(+100cm)

유량 0cm

유량 (+50cm)

유량(-50cm)압력

[bar]

유량

[ml/

hr]

주입압력 1bar 주입압력 0.3-0.5bar

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0bar

0.1bar

0.2bar

0.3bar

0.4bar

0.5bar

0.6bar

0.7bar

0.8bar

0.9bar

1bar

1.1bar

0ml

1ml

2ml

3ml

4ml

5ml

6ml

0hr 8hr 16hr 24hr 32hr 40hr 48hr 56hr

Flow Rate 0cm anapa +50cm

New anapa +50cm anapa -50cm

New anapa -50cm Pressure

Time [ hr ]

Flo

wRate

[ m

l/hr

]

Pre

ssure

[bar]

Higher pushing pressure, Lower impact from Potential

energy

Pushing Pressure : about 1

bar

Pushing Pressure :

about 0.5 bar

+50cm+50cm

-50cm-50cm

Pressure +50cm

Pressure +50cm

anapa New anapa

ananpa & anaplus

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Switch Valve(S/V)

If CO₂ gas exceeds

Set-volume

Switch Valve

Moves to left

CO₂ gas is released outside automatically

through SpecialAirway

Double Pressure Control System

ananpa & anaplus

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Product Balloon Pumps

Priming time About 2’30” About15’

Compare with other products

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• Priming is procedure to remove air inside

tube line and prevents air injected to

patient and contamination.

• All the air inside PCM is removed and

Priming time is shortened about 2’ 30”.

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• Easy to use, Grip type design

• Arched design prevents pushing the button accidently

=> The risk of over-dose is minimized.

Grip형

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• There are some cases that PCM clip is not removed after Priming.

• In case not remove PCM clip, Bolus volume keeps injecting to patient

additionally(over-dose) and it cause negative side effect to patient.

• To prevent this case, End-cap and PCM clip are linked by string and

can be removed together.

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• Hydrophobic Filter : Only air is passed

• No need to open End-cap to check the

completion of priming => Minimizing the risk of

contamination

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Flow restrictor, glass capillary has 3 layer rings to prevent

overflow.

=> Safe and constant flow is available.

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item Anaplus Balloon pumps

AccuracyAvg. Flow rate = Instantaneous Flow Rate= +/- 10%

Avg. Flow rate = +/- 15% Instantaneous Flow Rate = +/- 50%

Flow changeby Chamber position

+/- 0.8% per 10cm +/- 10% per 10cm

Priming Time About 2’30” About 10-15min

Filling Pressure <1.5kgf 5.4kgf – 9.3kgf

Residual Volume 1ml > 2ml <

Prevention of Over-dose

1. Remove PCM Clip & End-cap together2. 3-layer ring of Capillary housing

No

Air Removal

4 step system1. Remove air inside Chamber2. Remove air inside PCM 3. Remove air inside Tube line 4. Before patient connection: End-cap

2 step system1. Remove air inside Tube line2. Before patient connection: End-cap

Gas-Pressured Infusion Device

anapa & anaplus