SUBJECT INDEX

A Absorption and phosphate bond energy,

150-152 Acetyl phosphate, 109, 111, 112, 121. 128,

Activation of intracellular proteolytic en-

Activity of drugs, 193 Adenosine polyphosphate, 109, 11 1, 112.

Adsorption of enzymes, 331,332,344,345 Aerobic metabolism, 139-148 Aggregation of viruses, 57 Alimentary canal in low vertebrata, 374-378 Amination and transamination, 154, 155 Amino acids in proteins, 1, etc.

152- 154

zymes, 82,83, 85-88

114-116

racemic, enzymatic resolution, 94 residues, 19-21. 64

Amphibia, digestion, 402410 food, 402 gastric digestion, 403-407 intestinal canal, 377 resorption of food, 409, 410 secretion of gastri’c juice, 402, 403

391, 392,394,407,408,411,412 Amylaae in low vertebrata, 381. 383, 389.

“Anlage” theory of protein synthesis, 17 Anaerobic metabolism, 132-1 39 Anticatalaae, formation, 167 Arginine phosphate, 109, 111, 112, 118, 119,

Assimilating system in plants, reduced state,

Aawciationdiwociation of proteins, 17.18 Asymmetry of protein molecules, 23-28 Athiorhodaceae, 236, 280, 281, 289, 290.

128

202, 242-255

302, etc.

B Bacterial photosyntheses, 236,263-328

kinetics, 289-301 energeti CB. 3 14-3 19

Bacterial pigments, 235, 292, 293, 307-314 Bacteriochlorin, 309 Bacteriochlorophyll. 235, 292, 309, 313 Bacterioviridin, 313 Beef kidney enzyme, 82, 83 Beef spleen cathepsin, 81-84 Beef spleen enzyme preparation, 82, 84 Biliverdin precursor from catalaae. 167, 171

429

Biosynthesis by acyl phosphates, 152-154 Blackman period, 206-209. 213, 215 Blackman reaction, 205, 320 Blue substance from catalase, 170-172, 174‘

C

Carbohydrate resynthesis, 143-148 Carbon dioxide, reduction, 242-259, 279 Carotenoids and photosynthesis, 293, 308.

Catalase, absorption bonds, 168 action, mechanism, 168-170 adsorption, 165 anticatalaae, 167 chemical nature, 163-176 crystalline, 172-174 inactivation, 165 occurrence, 164 preparations, 172-173 prosthetic groups, 170 stability, 165

311. 313

Chemical kinetics of photosynthesis, 209-216 Chemo-autotrophic bacteria, 265,266 Chlorophyll fluorescence, 216

sensitizer, 232 Chloroplastin, 311 Chloroplaata, illuminated, 219-220 Chymotrypsin, specificity, 73-75 Coenzyme theory, 85, 88, 95 Collagen, 11, 12 Color changes in bacteria, 308 Copper protein enzymes, 183. 185 Cosubstrates, 95. 96 Creatinine formation, 118 Creatine. free and Dhosuhorvlated. 118 Creatine.phosphaie, 100, 169. 111, 113, 117.

Cyclol-cage structure. 29-33 118, 128

D

Dark metabolism of purple bacteria, 301-307 Denaturation of protein. 35-40 Di-adenosine polyphosphata, 114 Di-adenosine tetraphosphate, 114 Dicarboxylic acid oxidation, 142 Digestion in amphibia, 402410

fish. 385-402 low vertebrata. 371-417

Advances in Enzymology and Related Areas of Molecular Biology, Volume 1 Edited by F. F. Nord, C. H. Werkman

Copyright © 1941 by Interscience Publishers, Inc.

430 SUBJECT INDEX

reptiles, 410-412 vertebrata and invertebrata, 371-374

Diphosphoglyceric acid, 121 Diphosphopyridinoprotein enzymes, 180, 181 Diphosphothiaminoprotein enzyws, 184,

Drugs, effect on enzymes, 194, 196 185, 186

pharmacological activity, 193

E EEiciency of plants for the reduction of COZ,

Egg albumin, mol. weight. 14, 15, 22, 23 Elastin, 12. 13 Energetics of bacterial photosyntheues, 314-

Enzymatic activity of fish bile, 393, 305 Enzymatic synthesis, 332-334, 345 Enzymes, definition, 190

203

319

digestive, 371-374, 37s-383, 300-397,

effect of drugs, 194-196 and hormones, 190-192 identification, 186, 187, 190, 192 inhibitors, 194 table, 195. 196 in the living cell, 330, 331. 334-342, 346,

one-sided and reversible act,ions, 330 physiological role, 347-365 resolution, 94 specificity of prosthetic group and protein,

177, 178 structure, 193 synthesis of peptide bonds, 90-93, 94. 96 and trace substances, 177-198 turnover number, 178

407,408,411,412

347,366,367

Erepsin-in low vcrtcbrata, 391, 392, 407, 412 Ester phosphate. group potential, 103-105 Esterases, synthevizing and hydrolizing

activity in animal ti*sucs, 345

F Fat synthesis by 3cyl phosphates, 153, 154 Fermentation and phosphate bond energy,

132 and phosphorylation, 120

Fiber proteins. See Proteinsfibroicr Fish, digestion, 385-402

food, 385 intestinal canal, 375-377 secretion of gastric and pancreatic juice,

385-387 Flavoprotein enzymes, 181,182, 184 Fluoresrencc, bacteriochlorophyll, 313

green plants, 21G-219 and photosynthesis, 216,223-231

Fluoride inhibitioii of fermentation. 120 Folding of the peptide chain, 9.29

Food, utilization and resorption in low ver ta

Fructose, transformation into glucose, 152 brata, 397-401, 409-411

monophosphate, and saccharose syntheair in plants, 358-360

G

Gastric digestion in low vertebrata. 387-390.

Gastric juice, secretion in low vertebrata,

Gastro-intestinal proteinases, specificity,

Globular proteins. See Proteins globular Glucose, formation from fructose, 152 Glycolysis and phosphate bond energy. 132 Green pigment of green sulfur bacteria,

of purple bacteria, 292, 293. 308, 309, 310,

403-407. 410. 411

384-386. 402, 403

69-78

312, 313

312 Green sulfur bacteria, pigments, 312,313

metabolism, 236, 269 etc.. 281 table Group potential, definition, 102. 103

of phospho-organic compounds, 103-1 10 Group transfer as metabolic reaction, 154-

158

H Hair, elasticity, stretching, 8 Hemin from catalsae, 170, 171, 174 Hcmoglobin. mol. weight, 19 Hexosediphosphate, synthesis in withered

Hexosemonophosphatase. 360 Hormones, activity concentration, 187-190

leaves, 365

definition, 190 enzyme relationship. 190-192, 196

I Induction periods, photosynthesis, 220-232,

Inhibition, 194, 195, 196 Insulin-ensyme relationship, 191 Intestinal canal in low vertebrata. 375-378 Intestinal digestion in low vertebrata, 390-

397.407-409.411.412 Intracellular proteinases. 78-88 Invertase, synthesizing and hydrolizing ac-

tivity in living plants, 335339,343-365 Invertebrata, digestion, 371-374 Iron-phorphyrin in protein enzymes, 178.

246

179

K Keratin, supercontracted, ebsticity, X-ray

a-Keratin, X-ray andyais, structure, 8-1 1 analysis, structure, 7, 10

SUBJECT INDEX 43 1

&Keratin. X-ray analysis. structure 8-11 Kinetic8 of bacterial photoayntheses, 289-301

chemical, of photosyntheses, 209-216 of proteinases, 89,W

La-.:.albumin. mol. weight, 22.23 Light saturation of plants. 204 Linkages split by proteinases, 67 Lipase in low vertebrata, 380, 389, 394-395,

401

M Maltaae. low vertebrata. 381, 391, 392, 394.

408. 411. 412 Metabolic generation and utilization of

phosphate bond energy. 99-162 Metabolic reactiona, 95, 154-158 Metahohm, aerobic, 139-148

an..,,obic. 132-139 purple bacteria, 234-242, 264-269, 275-

281. 289. 292.301-307 sulfur. bacteria; 236, 265, etc., 269 etc..

Molecular weight of proteins, 14, 15, 18, 19. 270, 274. 278, 280, 281

20 Muscle fiber, stretching, X-ray analysis, 13 Muscular contraction and phosphate bond

Myosin in muscles, diffraction pictures, 13 energy, 101, 149

,J

N Narcotics, effect on enzymatic processes,

Nutrition and physiological function, 187 in leaves and fruits, 346, 356

0

Oxidation reactions in the living cell, 347 reduction reaction in anaerobic metabo-

lism, 102, 136-138 Oridiaing power of living plants, 336, 342 Oxygen liberation by illuminated chloro-

plasts, 219. 220

P Pancreatic juice, secretion in fish, 386. 387 Papain, 7S,80, 85-88, 92, 93 Pepsin. 39, 69-74

in low vertebrata, 372, 375, 377-379, 381. 382,388,389,394,403,404,406.410

Peptide bonds of amino acids, 2. 3, 29 enzymatic synthesis, 9Ck93, 94, 96 hydrolysis, 67 in proteins, 67, 69

folding, 9, 29, 40 Peptide chain, arranmment, 28-35

Peroxydase in the living cell, 347 Pharmacological activity of drugs, 193 Phosphatases. 336, 341, 365 Phosphate bond energy, 99-162 Phosphate cycle, 121-131 Phosphate esters. group potential 193-105 Phosphagens. 116-119 Phosphoenol pyruvic acid, 111. 119-121, 128 Phosphoguanidine linkages, 116-119 Phosphoglyceraldehyde, 125 PhosDhoalvceric acid. 119. 120 Phosphoglbyl phosphate, 109, 111, 112.

121. 128 Phosiholipids, 4. 5 Phospho-organic compounds, 103-1 10, 113 Phosphoric acid. 356-361 Phosphosaccharose, 360 Phosphorylation, 112. 120, 124-126 Photo-oxidation in plants. 232-234 Photoreduction in algae, 243 -248 Photosynthetic bacteria, 263-328 Photosynthetic unit, 209-212. 221 Photosynthesis, anaerobic, 242-255

Blackman period, 206-209, 213, 215 chemical kinetics, 209-216, 247, 248 and fluorescence, 216. 223 invertase, 350. 352. :;53 light and dwk reactions, 205,206,287 metabolism of the purple bacteria, 234-

in plants, 232-234 saturation phenomena 204-220

242, 264

Photosynthin, 312 Pigments, green sulfur bacteria, 312, 313

protein complexes, 311, 312 purple bacteria. 235, 292, 293, 307-314

Primary phosphorylation, 124-126 Prosthetic groups, biological

function, 4 catalasc, 170 enzymes, 177, 178, 186, 187, 190, 192, 193 proteins, 4 visual purple, 190

Proteases. See also Proleinaaea and Pro-

Proteascs in living plants, 336. 339, 340,

Proteinases. See also Proleases and Proteoly-

leolytic enzymes. 03

352-355, 361. 364, 365

tic enzymes: classification. 64 hydrolysis, 65, 66 gastro-intestinal. 69-78 intracellular, 78-85, 88 kinetics, 89. 90 specificity, 63-98 stereochemical specificity, 75. 82. 84. 85,

87, 93-94 Protein bonds, 39, 40 Proteins, amino acids, 2. 64

analysis, 2

432 SUBJECT INDEX

associationdimciation, 17, 18 classification, 15, 16. 20, 23 cyclol-cage structure, 29-33 denaturation, 35-40 enzymes, 177, 178 fibrous, 5-13 globular, 13-40 hydration, 19 metabolism, 95 mo1.-weight, 19, 20 peptide linkage. 2. 67, 09 with phospholipids, 4, 5 prosthetic groups, 4 shape of the moleculcs. 23-28 side chains, 3, 4 structure, 1-42 synthesis. 17, 154 viruses, 50 Big-zag peptide chains, 32-34

Proteolysis, 344. 345 Proteolytic enzymes.

Protoplasm, energetic state, 333, 334 Purple bacteria, fluorescence, 313, 314

See also Proteasea and Proteinasea, 63, 78

metabolism, 234-242, 264-269, 275, 280. 281, 289, 290, 291. etc., 301-307, 320

pigments, 235,292, 293,307-314 Purple sulfur bacteria, metabolism, 236, 269,

etc., 270. 274, 278, 280, 281, 284, 285, 289, 292. 302, etc.

Pyruvate oxidation, 1'41

R Red pigments of purple bacteria, 292. 293,

Reptiles, digestion, 410-412 308,311,312

food, 410 intestinal canal, 378

Resorption of food, 397-401, 409-411. 373,

Rhodoviolascin. 311 374

s Saccharose, enzymatic synthesis, 336, etc.,

Salivary glands in low vertebrata, 374, 375 Saturation phenomena in photosynthesis,

Secretion of digestive enzymes, 373, 374 of gastric and pancreatic juice, 384-387,

338, 343, 345, 350, 356-361

204-220

402,403 Shape of protein molecules, 23-28 Side chains, amino acids, 3, 4, 40 Silk fibroin. X-ray analysis, structure, 7 Size of protein molecules. Bee Mol. w&ht Specificity, prosthetic group, 177, 178

Spirilloxantbin, 310, 311 proteinases, 63-98

Stereo-configuration of the amino acids of proteins, 2

Stretching of hair, 8 Sulfanilamide, theory of action, 165 Sulfur bacteria. metabolism. 238, 265, etc.,

269, etc., 270, 278, 280, 281 Swine pepsin, specificity, 68-71

T Thiamin. carbohydrate resynthesis, 147 Thiorhodaceae, 236, 280, 281. 285, 290. 302,

etc.. 308 Thyroxine, prosthetic group, 191. 192 Tissue proteolytic enzymes, specificity, 81 Tobacco mosaic virus, activity, 45

centrifugation 47 radiation, 48 size and shape, 56

Trace concentration, definition. 188 Trace metals, 189 Substances and enzymes, 177-198 Transamidination. 157, 158 Transamination, 154, 155. 157, 158 Transphosphorylation, 126-131 Transmethylation, 155-157 Trypsin in low vertebrata, 380, 383, 391-

395,408,412 inactivation of catalase, 185 specificity, 75, 76

Triphosphopyridinoprotein enzymes, 181 Tumor extracts. specificity, 83,G Turnover number for enzyme efficiency, 178

U Ultracentrifugation for mol. weight of globu-

lar proteins, 14, 15

V Van Niel's theory of photosynthesis, 234-

Vertebrata and invertebrata, digestion, 371-

Vertebrata, low, anatomy of alimentary

Virus, activation, 49

242

374

canal, 374-378 low, digestion, 371417

activity and p H . 44 activity and electrical charges, 45 crystal form, 69 electronic microscope, 57 freezing, 47 phyeico-chemical problems, 43-82 and radiation, 48 shape and size of particles, 55

electrical charges, 48 Virus protein, aggregations, 60

Visual purple, Vitamin A 88 prosthetic group, 190

SUBJECT INDEX 433

Vitamin A ae prosthetic group of visual prosthetic groups of ensymes, 186, 187.

Vitamin-eneyme relationship, 187

purple, 190 190 Vitellin, association with a phosphoripid, 5

Vitamins, necessary in diet, 185, 187 X definition. 190 X-rays and virus, 48