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Adult Immunization 2010
MMR Vaccine Segment
This material is in the public domainThis information is valid as of May 25, 2010
Measles-Mumps-RubellaVaccine (MMR)
• Contains live attenuated viruses• 1-dose efficacy varies from 80%
(mumps) to 95% (measles and rubella)
• Duration of immunity probably lifelong
• Schedule is 2 doses• All adults born in 1957 or later should
have documentation of at least 1 dose (or other evidence of immunity)
Adults at High Risk forMeasles
• College students
• International travelers
• Healthcare personnel
MMR VaccineContraindications
• Severe allergic reaction to vaccine component or following prior dose
• Pregnancy
• Immunosuppression
Measles Vaccine and HIV Infection
• MMR recommended for persons with asymptomatic and minimally symptomatic HIV infection
• NOT recommended for persons with evidence of severe immuno-suppression
• Prevaccination HIV testing of an otherwise healthy person not recommended
MMR Vaccination of Women of Childbearing Age
• Ask if pregnant or likely to become so in next 4 weeks
• Exclude those who say "yes“
• For others
– explain theoretical risks
– vaccinate
MMR VaccinePrecautions
• Moderate or severe acute illness
• Recent receipt of a blood product
• History of thrombocytopenia or thrombycytopenic purpura
MMR Adverse Reactions
Fever 5%-15%
Rash 5%
Joint symptoms 25%
Thrombocytopenia <1/30,000 doses
Parotitis rare
Deafness rare
Encephalopathy <1/1,000,000 doses
National Center for Immunization and Respiratory Diseases
Contact Information
• Telephone (800) CDC-INFO
• Email [email protected]
• Website http://www.cdc.gov/vaccines/
• Broadcast Updates and Resources
Web Page
http://www.cdc.gov/vaccines/ed/webcasts.htm