Additional Therapeutic Uses of ES

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    () Lecture8:

    AdditionalTherapeuticUsesofElectricity

    100 1

    AdditionalTherapeuticUsesof

    Electricity

    Woundmanagement

    Osteogenesis

    Edemareduction

    Peripheralcirculation

    Incontinence

    2

    ESforWoundManagement

    Wound abreakinthecontinuityofsofttissuecausedbyphysical,

    chemicalorbiologicalinsult

    Complications:chronicinflammation,infection,andscarring

    associatedwithotherimpairments,suchaspain,decreasedmobilityandmotorfunction

    ES asdirectintervention,oradjunctstootherwound

    management

    PatientsreferredtoPTforEStreatmentareusually: Chronicwoundnotresponsivetoothertreatment:Neuropathic

    ulcer,pressureulcer

    Orneedtoacceleratehealingprocess

    3

    PhasesofWoundHealing Phase1

    Inflammatoryphase(day1 6)

    Initialvascularconstriction:decreaselocalblood

    flow,allowmoreefficientclotting

    Vasodilation:deliverchemicals,cells,nutrientsandoxygentoinjuredtissue

    Promotecapillarypermeability

    Chemotaxis:bodilycells,bacteria,andothersinglecell

    ormulticellularorganismsdirecttheirmovements

    accordingtocertainchemicalsintheenvironment

    Increasefibroblastandmacrophageactivity

    4

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    PhasesofWoundHealing Phase2

    Proliferativephase(day3 20)

    Reepithelialization:regrowskinoverthewound

    Toprovideaprotectivebarriertopreventfluidandelectrolytelossandtodecreasetheriskofinfection

    Fibroblastsarriveandbegintoproducecollagentorebuildthesiteofinjury

    Neovascularization Developmentofanewbloodsupplytotheinjuredarea

    Newvesselsareneededtosupplyoxygenandnutrientstotheinjuredandhealingtissue

    5

    PhasesofWoundHealing Phase3

    Remodelingphase(day9on)

    Maturationphase

    Continuedfibroblasticandcollagenactivity

    Collagenundergoesbothsynthesisandlysis

    balancebetweenthesetwoprocessesdetermines

    theeventualamountofscarformation

    Thisphaseischaracterizedbyscarcontractionand

    mayalsoincludescarhypertrophy

    6

    RationalesForUsingESForWound

    Management

    Skinbattery&currentofinjury

    Galvanotaxis

    Speeduphealingprocess

    Antimicrobialeffect

    7

    SkinBattery

    Transepithelial potentialbetweenthedermisandepidermis

    Whentheskinisdamaged,thedifferenceinpotentialisbelievedtobethesourceofthecurrentofinjury

    Thiscurrentisatriggertowoundhealingandalsoassociateswiththemoistwoundhealingprocess

    Ifwoundsarepermittedtodry

    ceasethecurrentofinjury UseEStoinfluencethecurrentofinjuryandthelateralelectricfield

    thatexistsinareasofskindisruption

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    Galvanotaxis Cellwithchargeattractedtoanelectricfield

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    SpeedUpHealingProcess Augmentationofcollagensynthesisandproliferationof

    fibroblasts Fibroblastsnormallymigrateintothehealingwound,especially

    duringtheproliferativephase

    ESincreasesDNAsynthesisandcollagensynthesis

    Promoteangiogenesisandwoundmicroperfusion EScouldstimulatecapillaryregrowthintothewound

    Enhancedmicrocirculation inchronicwoundinresponsetoES

    Enhancingtherateofepithelialization Fasterepithelialization

    Evidenceshowedthatifwoundstreatedwithanode7days,orwithcathodeonthefirstdayandanodefortheremaining6days

    Enhancingbloodflowtowounds Enhancingbloodflowtowoundsbytheuseofelectrical

    stimulationappliednearthewound10

    Antimicrobialeffect

    Electricalstimulationhasbacteriostatic(inhibitgrowth)orbactericidal(killbacteria)effectsonvariouspathogenicorganismsthatarecommonlyfoundtoinfectwounds

    Electrodepolarityforantimicrobialeffects CathodeforPseudomonasaeruginosa ()

    BothanodeandcathodeforStaphylococcusaureus()

    Electrodecompositionforantimicrobialeffects Electrodesconsistingofsilverwireshowedsuperior

    effectswhencomparedwithstainlesssteel,platinum,orgoldwireelectrodes

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    ESForWoundManagement

    Cleansewoundthoroughly,removedead

    tissuesandpetrolatumproducts

    Cover/fillwoundspacewithgauzepads

    soakedinsalineorhydrogel

    Placeanelectrodeonthegauzepacking,cover

    withdrygauze,holditwithbandagetape

    Dispersiveelectrodeusuallyproximaltothe

    wound

    12Source:Woundcareinformationnetwork,SUSSMANPHYSICALTHERAPYINC.

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    Microcurrent ES Polarity&electrochemicalreaction

    Cathode(negative):raisethepHtoalkalinityformingmaybeusedforitsbactericidaleffectorasanadjuncttodebridementbecauseofitssclerolytic ability(decreaseproteindensity)tosolubilizethrombiandnecrotictissue

    Anode(positive):lowerthepHtoacidityformingmaybeusedforitseffectofsclerosing tissueandcoagulatingbloodleakingfromsmallvesselsmayalsoaugmentclosureofthewoundbyproducingacongealedscar

    Ifinfectionwithorganisms,suchasEcoliandPseudomonas

    aeruginosa (

    )ispresent,thenegativeelectrodeshouldbeleftinthewoundareauntilthesignsofinfectionarenotevident.Thenegativeelectroderemainsinthewoundfor3daysaftertheinfectionclears.

    IfthewoundisinfectedwithbacteriasuchasStaphylococcusaureus (),thepositivepolemaybeamoreappropriatechoice

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    Microcurrent ESApplication Thenegativeelectrodeispositionedinthewoundareafor

    thefirst3days;after3daysthepolarityisreversed

    Ifthewoundsizestopsdecreasing,thenreturnthenegativeelectrodetothewoundareafor3days

    Ingeneral,thesecondelectrodeisapproximatelythesamesizeastheactiveelectrodeandisplacedat15to30cmawayfromthewound

    14

    RecommendedProtocol

    Currentintensity

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    PolarityConsideration&Protocol Selectionofpolarity

    Usuallyinitiatedwiththecathodeastheactiveelectrode

    Afterseveraldaysoftreatmenttheelectrodepolarityisreversedtothepositivecharge

    Negativepolarityisusedifmicroorganismsarepresentcontinuetousenegativepolarityuntilthewoundisculturefreefor3days

    Positivepolarityisusedifthewoundisculturefreeoris

    usedafterthewoundisculturefreefor3days Recommendedprotocol

    Frequency:30 130pps

    Amplitude:subthresholdtomusclecontraction

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    ESForWoundHealing HighVoltage

    PulseCurrent

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    ESForWoundHealing HighVoltage

    PulseCurrent Signsofadverseeffects

    Skinirritationortinglingundertheelectrodes

    Pain

    Precautions Transcerebralstimulation

    Stimulationovertheeyes Youngchildrenunderage3years

    Contraindications

    Presenceofmalignancy

    Activeosteomyelitis

    Topicalsubstancescontainingmetalions:povidoneiodine,zinc,silversulfadiazine,mercurochrome

    Electronicimplants

    19

    ESForOsteogenesis

    10%ofthe7.9millionannualfracturepatientsintheUnited

    Statesexperiencenonunionand/ordelayedunions

    Severalmethodshavebeenusedtopromotebonehealing Electricalstimulation

    Lowintensitypulsedultrasound

    Electromagneticstimulation

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    StagesofBoneHealing Inflammatorystage

    Repairstage

    Remodelingstage

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    Hematoma

    Cartilaginous

    callus Bonycallus Remodeling

    1.Inflammatorystage Hematomaformswithinthefracturesite(first

    fewhourstodays)

    Cleanupdeadtissues

    Callusformation

    Thisstagelasts2 4weeks,overlapswiththe

    nextstage

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    2.Repairstage

    Cartilaginouscallus

    Painandswellingsubsideasthebonyfragmentsunitedby

    cartilaginoustissue

    Osteoclastsremovedeadbonefragments

    Hardcallus Cartilagehardening fromeachendoffracturetowardthecenter

    Thisstagelasts1 2months

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    3.Remodelingstage

    Weak strongbonmaterial

    Bonereturnstoitsoriginalshapeand

    structure

    Remodelingoftheboneoccursslowlyover

    monthstoyearsandishelpedbymechanical

    stress(i.e.weightbearing).

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    RationaleForUsingESFor

    Osteogenesis Chemicalgradientswithinthebone

    arethesourceofbioelectricpotentials

    Normalbonehaspiezoelectricproperties Highercellularactivity(epiphysial

    platearea) morenegative

    Bonegenerateselectricalpotentialsinresponsetomechanicalstress Compression Negative

    Tension Positive

    Thepolaritychangesafterdiaphysisfracture

    EScausesionicmigration

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    Microcurrent ES Polarityofstimulation

    Anegativeelectrodewasplacedclosetobutdistaltothefracturesite

    Apositiveelectrodewasplacedproximaltotheimmobilizingdevice

    Recommendedprotocol Currentintensity:justperceptibletothepatient

    Pulseduration:ContinuousorpulsedDCwithlongest

    durationallowedontheunit(100 200msec) Frequency:lowestfrequencyallowedontheunit(5 10

    pps)

    Treatmentduration:30minutes 1hour

    Treatmentfrequency:3 4timesperday

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    TENS

    Ifthefracturesiteisenclosedinaplastercast,electrodes

    shouldbeplacedproximalanddistaltothecast,2or4

    electrodesareused

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    TENSApplication Ifthefracturesiteisfreeof

    casting,3basicpatternsare

    available

    With2electrodes,oneplacedon

    eithersideofthefracturesite,

    about6inches(15cm)apart

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    TENSApplication With4electrodes,across

    pattern,about6inchesapart,

    withthecrossingpointdirectly

    overthefracturesite

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    TENSApplication Ifthefracturesiteisfreeof

    casting.With2electrodes,a

    sandwichpattern,withthe

    fracturesitebetweenthetwo

    electrodes

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    TENS

    Recommendedprotocol Frequency:thehighest

    frequencyavailableonunit(120Hz)

    Pulsedwidth:thewidestwidth(300 s)

    Intensity:thelowestpossible,barelysensedbypatient

    Treatmentduration:1hour/session

    Treatmentfrequency:4times/day

    Sideeffects Analgesiawasreportedby

    patientswhocomplainedofpain

    asasymptomofthenonunion

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    ESForEdemaReduction

    Rationale

    Polaritymovesnegativelychargessubstancethatcausededema

    Sensorylevelstimulation Polarityofelectrode

    Tousethepolarityofanelectricalstimulustorepelsimilaritychargedsubstancesfromtheedematousarea

    Becausebloodcellsandplasmaproteinscarryanegativecharge anegativeelectrodeplacedoveranedematousareamayrepelthesenegativelychargedsubstancesfromtheareaofstimulation decreasingtheamountofedemathroughafluidshift

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    ESForEdemaReduction Rationale 1

    Sensorylevelectrical stimulustorepelsimilarity

    chargedsubstancesfromtheedematousarea

    Bloodcellsandplasmaproteinscarryanegativecharge

    anegativeelectrodeplacedoveranedematousarea

    mayrepelthesenegativelychargedsubstancesfrom

    theareaofstimulation decreasingtheamountof

    edemathroughafluidshift

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    Rationale 2 Microcurrent stimulationofthelocal

    neurovascularcomponents

    Amicroamp stimulationmaycausea

    vasoconstrictionandreducethepermeabilityof

    thecapillarywallstolimitthemigrationofplasma

    proteinsintotheinterstitialspaces

    Thiswouldretardtheaccumulationofplasma

    proteinsandtheassociatedfluiddynamicsofthe

    edemaexudate

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    Rationale 3

    Motorlevelstimulation

    Electricallyinducedmusclecontractioncan

    effectivelyleadtoareductioninedemaby

    mobilizingtheedematomovefromtheinterstitialcompartmenttothebloodvascularsystemand

    lymphaticsystem

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    ESForEdemaReduction HVPC

    Applicationtechnique

    Waterimmersionelectrodetechniqueismore

    effectivethanusingsurfaceelectrodes

    Polarityofstimulation Activeelectrodesisnegative

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    HVPCRecommendedProtocol Sensorylevelstimulation

    Intensity:10%lessthanneededtoproduceavisiblemusclecontraction

    Frequency:high(120pps)

    Timeoftreatmentafterinjury:beginimmediatelyafterinjury

    Treatmentduration:30minutesevery4hours

    Motorlevelstimulation Intensity:strong,comfortablemusclecontractions

    Frequency:35 50pps

    Ontime:5 10sec;Offtime:5 10sec

    Theparttobetreatedshouldbeelevated

    AROMmaybeencouragedatthesametimeifitisnotcontraindicated

    Treatmentduration:20 30minutes

    Treatmentfrequency:2 5timesperday

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    ESForPeripheralCirculation Introduction

    Mostcommonlyappliedtopreventpostoperative thromboemboliccomplicationsandtoimprovecirculation

    Factorscontributingtotheformationofathrombosis Changesinbloodflow

    Changesinbloodcoagulability

    Changesinthevesselwall

    RationaleforusingES Electricalstimulationofthecalfmusclespreventedadecrease

    intherateofvenousbloodflowinthelegsduringsurgeryandthereforedecreasedthefrequencyofdeepvenousthrombosis

    Increasedcapillarybloodflowinthestimulatedmusclesresultsfromacombinationofreflexivevasodilationandanincreaseincapillarygrowthduringlongtermelectricalstimulation

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    ESForPeripheralCirculation

    InterferentialcurrentorRussianstimulation Electrodeplacement:Oversensorynerves

    Recommendedprotocol Currentintensity:maximumtoleratedtingling(sensorylevelstimulation)

    Frequency:50 200bps

    Cycleduration:20 100 s

    Dutycycle:50%ifRussianstimulation Treatmentduration:20 60minutes

    Lowfrequencystimulators Electrodeplacement:Overmotornervesofinnervatedmuscles

    Recommendedprotocol Waveform:balancedasymmetricalbiphasicpulsedcurrent

    Currentintensity:motorresponse

    Frequency:30 100pps

    Treatmentduration:30 40minutes

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    ESForIncontinence Indications(1)

    Stressurinaryincontinence

    Involuntarylossofurinewhentheintravesical (withinbladder)pressureexceedsthemaximumurethralclosurepressureintheabsenceofdetrusoractivity

    Smallamountsofurinearelostconcurrentwiththeincreasedintraabdominalpressure

    Urgeurinaryincontinence Involuntarylossofurineassociatedwithanuninhibiteddetrusor

    contractionthatoverwhelmsthesphinctermechanism

    Mixedurinaryincontinence

    Urinaryfrequencyorhesitancywithpelvicfloordyssynergia

    40

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    ESForIncontinence Indications(2)

    Fecalincontinencerelatedtopelvicfloorweakness

    Levator syndrome Painintheregionofthecoccyx

    Painfulspasmsofthemusclesaroundtheanuswithoutknowncause

    Althoughbowelmovementsmatnotbepainful,

    patientsoftenreportdisturbedbowelfunction,constipation,orfrequency

    Interstitialcystitis Aconditionofoversensitivityofthebladder

    41

    ClinicalApplication Purpose

    Tohelpthepatientidentifythepelvicfloormuscle

    location,provideproprioception,andassistthe

    contraction

    Toachieveautonomicdampeningofthesebladder

    contractionsbyaugmentingsympathetic

    dominance

    Electrodeselection:Whenpossible,an

    internalelectrodeispreferred

    42

    RecommendedProtocols

    Vaginal andanalplugstimulation:aanalorvaginalplugwithtwoembeddedringelectrodes

    Patientsposition:beginwiththepatientinanantigravityposition(ie,relaxedhooklyingorsidelyingwithoneortwopillowsunderthepelvisorbetweenthelegs)andslowlyprogresstostanding

    Themostcomfortablecurrentsaredeliveredbycircularelectrodes,whichareabletodispersecurrentoverlargesurfaceareas

    Frequency:5 50Hz Ahigherfrequencyof50Hzismostamenabletoinnervatedmuscle it

    workswelltoteachmusclecontraction,proprioception,andawareness

    Alowerfrequencyof5 20Hzismostamenabletotreatdetrusorinstabilityandurgency

    Treatmentdurationandfrequency:2or3minutesofstimulation1 3timesadayisagoodbeginning,graduallybuildingupto15minutes1 2timesaday

    Afterthefirstfewsessions,whenpatienthasbeenabletoidentifythecontraction, askthepatienttocontractwiththecurrent,relaxinginbetween

    43

    InterferentialCurrent

    Pelvicfloorstimulation

    Electrode:externalelectrodes

    Patientsposition:asemireclined positionwiththehipsandkneesflexedandsupported

    Electrodeplacement:bipolartechnique Female:oneelectrodewasplacedunderischial tuberositywitha

    secondelectrodeovertheanteriorperineum,immediatelyinferiortothesymphysis pubis

    Male:electrodesplacedoneachsideoftheglutealcleft,justanteriortotheanus

    Currentintensity:50 80mA,maximumlimitofpatientcomfort

    Frequency:asweepfrequencyof10 50Hzorafixedfrequencyof50Hz

    Treatmentduration:30minutes

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    TENS Purpose:

    Tobemoreeffectiveinrelievingpelvicandperineal pain

    Tobeusefulintreatingdetrusorinstability

    Electrodeplacement:Relatedacupuncturepointsareuseful Spleen6(Sp 6):3cmdirectlyabovethetipofthemedial

    malleolusontheposteriorborderofthetibia

    Spleen10(Sp 10):withkneeflexed,2cmabovethesuperiormedialborderofthepatellaonthebulgeofthemedialportion

    ofquadricepsfemoris Largeintestine4(LI4):inthemiddleofthe2ndmetacarpal

    boneontheradialside

    Acrossedfashionoverthelowerabdomenorlumbarsacralareas

    45

    TENSParameters Mode:conventionalsetting

    Currentintensity:sensorylevel

    Frequency:60 100Hz

    Pulsedduration:100 150 s

    Treatmentduration:20 30minutes

    Treatmentfrequency:1 5timesaday

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