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ADC Ed Core Alzheimer’s Association Update

Maria C. Carrillo, Ph.D. Vice President, Medical& Scientific Relations

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Global Research & Development Funding Trends

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Adapted from appropriations progress charts by the American Association for the Advancement of Science.

Cell 2013 Jul 3 154(1): 16-19

US Research Funding Trends

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570

study sites are listed on

TrialMatch

165

studies are listed on

TrialMatch

As of August, 2013

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Person with the disease or caregiver or physician or healthy volunteer completes a disease-specific profile via phone or internet

or

1 Unique profile compared to structured match criteria 2

From unbiased match results, individual selects trial matches & cities; and with permission…

3 Alzheimer’s Association Contact Center specialists speak to every matched individual

4 5

Participant then calls trial site directly.

Profile Match Criteria

works How

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40,000+

people have completed a

profile

13,500+

people have been referred to a study site

As of September, 2013

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How does compare

• to the general population (especially those 65 and older)?

• to people with Alzheimer’s and other dementias?

• to caregivers for people with Alzheimer’s and

other dementias?

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? Who is

FY 2013 data

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Race/ethnicity

FY 2013 data

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Race/Ethnicity comparison Population aged 65+

U.S. Census Bureau data (2010) FY 2013 data

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Percentage of Americans with Alzheimer’s and other dementias

Facts & Figures, 2010

2.9 9.8

26.9

12.4

32.5

54.6

9.3

23.7

44.8

65-74 75-84 85+

White (Non-Hispanic) African-American Hispanic

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Gender comparison Population aged 65+

with Alzheimer’s

Facts & Figures 2013 FY 2013 data

Population aged 65+ with Alzheimer’s

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Education

FY 2013 data

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The next generation of TrialMatch will be:

• Smarter • Responsive & Engaging • Personalized • Diverse

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Person with the disease or caregiver or physician or healthy volunteer completes a disease-specific profile via phone or internet

or

1 Unique profile compared to structured match criteria 2

From unbiased match results, individual selects trial matches & cities; and with permission…

3 Alzheimer’s Association Contact Center specialists speak to every matched individual

4 5

Participant then calls trial site directly.

Profile Match Criteria

works How

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Person with the disease or caregiver or physician or healthy volunteer completes a disease-specific profile via phone or online

or

1 Unique profile compared to structured match criteria 2

From match results, selects trial matches and receives match info via TM online account

3 Every 2 weeks an automatic search for new trial matches sends an email alert if new matches found AND **New national trials will trigger automatic email alert to matched individuals

4 5

Participant then calls trial site directly.

Profile Match Criteria

WILL WORK HOW

Traditional TM Service: Individual can request to speak to an Alzheimer’s Association Contact Center Specialist

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www.alz.org/research

Thank you for your time!

18 alz.org