Adams, Grace Understanding the contribution of inositol ... · Single cell RNA sequencing to identify transcriptional targets of the MAFF transcription factor 93 Bodega, Beatrice

Posters A-Z

Adams, Grace Understanding the contribution of inositol phosphate signalling to class-1 HDAC complex function

63

Aeby, Eric Breaking the symmetry: Tsix RNA degradation regulates random X-chromosome inactivation

64

Akouchekian, Mansoureh The possible role of amyloidosis in autism spectrum disorder 65

Alberge, Jean-Baptiste 5hmC dynamics during multiple myeloma progression 66

Alcaraz, Nicolas H3K27ac: from interaction to enhancer transcription 67

Alfassam, Haifa SUMOylation as a regulatory mechanism for the SOX3 transcription factor

68

Ali, Ibraheem Acetylation of the RNA Polymerase II CTD Recruits RPRD1A and RPRD1B Proteins and Promotes Serine-5 Dephosphorylation

69

Amândio, Ana Rita Dynamics of the HoxD regulatory landscape 70

Ambrosi, Christina Exploring the conditional essentiality and function of SETD2 during cellular differentiation

71

Anagu, Linda Stress, sirtuins and severe malaria 72

Angel, Andrew Modelling the Dynamics of Transcription 73

Aoi, Yuki Acute depletion of NELF reveals a two-step regulation of promoter-proximal pausing of RNA polymerase II

74

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EMBL Conference: Transcription and Chromatin

Appel, Lisa-Marie The SPOC domain: A novel reader of the CTD code 75

Arecco, Niccolò SETD5 impedes RNA-PolII occupancy at neurodevelopmental genes in ESCs

76

Azouz, Abdulkader Eomes-Dependent epigenetic reprogramming of CD8 T cells leads to the aquisition of memory phenotype

77

Bacon, Curtis Mechanisms of RNA Polymerase II transcriptional activation by KAP1/TRIM28

78

Balaban, Can Role of Nuclear Lipid Islets in RNA Pol II transcription 79

Baluapuri, Apoorva Myc Represses Coding and Non-coding Genes by Sequestering Transcription Elongation Factors into Unproductive Complexes

80

Ban, Hyoju Novel heterochromatin factors identified from S.pombe genome screening

81

Bandiera, Roberto Cross talk between transcription elongation, splicing and RNA decay defines adult stem cell fate.

82

Barbieri, Elisa An Integrator complex subunit primes enhancers to modulate cell fate determination in hematopoiesis

83

Barboric, Matjaz Stimulating Pol II pause release through the RBM7:P-TEFb axis is at the core of cellular DNA damage response

84

Barral, Amandine SETDB1/H3K9me3 prevents illegitimate transcriptional initiation 85

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Posters A-Z

Bartusel, Michaela Moelcular and functional characterization of a novel locus associated with orofacial clefting

86

Beagrie, Robert A. Identifying transcription factors linked to gene expression changes during a key cell state transition in mouse red blood cell development

87

Beira, Jorge V. Epigenetic Plasticity: Integrating signaling inputs with chromatin regulators to direct tissue regeneration or tumorigenesis

88

Beltran, Antoni The origin and evolution of nematode piRNAs reveals the mechanistic basis of piRNA transcription

89

Bentsen, Mette ATAC-seq footprinting analysis reveals transcription factor dynamics in early embryonic development

90

Beyes, Sven The proto-oncogene MYB is a directly repressed target gene of the EMT master regulator SNAIL1

91

Bhuiyan, Tanja Epigenetic and genetic control of core promoter function 92

Blank, Volker Single cell RNA sequencing to identify transcriptional targets of the MAFF transcription factor

93

Bodega, Beatrice A novel class of L1 chromatin enriched transcripts maintains T lymphocytes’ cell identity and regulates their differentiation

94

Boehning, Marc RNA polymerase II clustering through CTD phase separation 95

Bogdanovic, Ozren Vertebrate-like DNA methylation remodelling in the chordate Amphioxus 96

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Bojcsuk, Dora Presenter: Balint, Balint Alternative super-enhancers result in similar gene expression in different tissues

97

Bolt, Christopher Chase Differential regulation of the HoxD locus in the urogenital sinus 98

Bourdareau, Simon Genetic control and chromatin dynamics of life-cycle pathways in the brown alga Ectocarpus sp.

99

Bozek, Marta Regional differences in enhancer accessibility during the establishment of spatial coordinates in Drosophila blastoderm

100

Brattås, Per Ludvik Widespread contribution of transposon-derived transcripts in human brain development

101

Breimann, Laura Characterising transcription regulation by dosage compensation in C. elegans

102

Brind'Amour, Julie LTR retrotransposons transcribed in oocytes drive species-specific, heritable changes in DNA methylation

103

Bruzzone, Maria Jessica Distinct patterns of Histone Acetyltransferase and Mediator deployment at yeast protein-coding genes

104

Bultmann, Sebastian TET1 drives global DNA demethylation via DPPA3-mediated inhibition of maintenance methylation

105

Bunina, Daria Chromatin accessibility and transcriptional landscapes during normal neurodevelopment

106

Cannaco, Enrico Deciphering the role of histone methyltransferase SETD1A in schizophrenia

107

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Posters A-Z

Carnesecchi, Julie Deciphering transcriptional interactive networks, a spatiotemporal “Hoxtory”

108

Carriço, Renata Presenter: Bessa, Jose The zebrafish pancreas regulome, from prediction to disease 109

Chammas, Paul PRC2-associated factor EPOP balances lineage commitment in mouse pre-implantation embryo

110

Cheung, Alan The cryo EM structure of the Tra1 subunit from coactivators SAGA and NuA4

111

Ciriello, Giovanni Presenter: Zufferey, Marie Exploring differential activation of topologically associating domains 112

Cossa, Giacomo ARK5 regulates pre-mRNA splicing through the inhibition of PP1ß activity on chromatin

113

Cowling, Victoria Neural differentiation requires mRNA cap methyltransferase-dependent transcriptional repression of pluripotency genes

114

Cunliffe, Vincent Epigenetic sensitivity of the Glucocorticoid Receptor feedback regulator fkbp5 to glucocorticoid signalling arises during zebrafish brain development and persists across the life course

115

Dalcher, Damian Presenters: Dalcher, Damian; Santoro, Raffaella

NoRC complex regulates chromatin architecture of ground state pluripotent stem cells

116

Decker, Tim-Michael Presenter: Ma, Guoli Analysis of RNA Pol II CTD phosphorylation after inhibition of CDK9 analog-sensitive kinase in vivo

117

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Deindl, Sebastian Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1

118

Delahaye, Celia Characterisation of the non-canonical zinc finger protein ZFP263 in mouse

119

Dellepiane, Nefeli Identifying functional non coding variation associated with a human quantitative trait: Central Corneal Thickness as an example

120

Dever, Kristy A role for the RNA Polymerase II-CTD phosphatase, FCP1, and CDK8 in the oxidative stress response

121

Di Stefano, Luisa A dual role of dLsd1 in oogenesis: regulating developmental genes and repressing transposons

122

Díaz, Noelia Zebrafish 3D chromatin maps reveal conserved principles of chromatin organisation throughout vertebrates

123

Djakovic, Lara Analysis of histone deposition in HSV-1 induced transcription read-through

124

Dobersch, Stephanie HMGA2 mediated histone deposition is required for TGFB1 induced transcription

125

Domsch, Katrin Maintenance of lineage-Fate Restriction by the Multi-lineage Transcriptional Regulator Ubx in Drosophila development

126

Dong, Wenbo The conserved bromodomain AAA-ATPase Abo1 is a mediator of facultative heterochromatin regulation in fission yeast

127

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Posters A-Z

Downes, Damien A comprehensive bioinformatics to genome editing pipeline for identification of causative regulatory SNPs and target genes from GWA studies

128

Durant-Vesga, Jennifer Role of hox transcription factors and TALE cofactors during renal precursors’ specification of the Xenopus embryo

129

Eckersley-Maslin, Melanie Dppa2 and Dppa4 are master positive regulators of the zygotic transcriptional network

130

Eeckhoute, Jerome Organizing combinatorial transcription factor recruitment at cis-regulatory modules

131

Endres, Theresa PAF/MYC complex assembly controls MYC-dependent transcriptional elongation

132

Enervald, Elin Rif1 plays a critical role in X-chromosome inactivation by enabling Xist RNA expression

133

English, David Identifying HDAC1 Proximal Proteins in Mouse Embryonic Stem Cells 134

Engström, Ylva Antagonistic regulation of gut immune homeostasis and stem cell activity by POU/Oct transcription factor isoforms

135

Erceg, Jelena Trans inter-homolog pairing in haplotype-resolved genomes 136

Esnault, Cyril G-quadruplexes shape the chromatin landscape and are probablepromoter elements

137

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Ezerskyte, Monika O6-methylguanine-induced transcriptional mutagenesis reduces p53 tumor suppressor function

138

Fadason, Tayaza Prioritisation of target genes in the GWAS Catalog using chromatin interaction and expression quantitative trait loci data

139

Fallatah, Bodor Chromatin associated Ago1 regulates MyoD expression by mediating enhancer-promoter interactions in mammalian cells

140

Fang, Liang ATAC-sequencing reveals key transcription factors involved in EMT phenotype of colon cancer stem

141

Fanourgaki, Smaragda Eliciting the interplay of active transcription and H2B ubiquitination in the maintenance of genome integrity

142

Fernandes, Ana Miguel Exploring RNA polymerase II regulation in the biogenesis of circular RNAs

143

Ferreira, Fábio Júnio Transcriptional cis regulation of FOXM1 during aging 144

Figuerola, Elisabet EWS-FLI1 alters the H3K27me3 positioning across Ewing sarcoma genome

145

Fischer, Veronique The role of the SAGA and ATAC coactivator complexes for RNA Polymerase II transcription in mouse embryonic stem cells

146

Fitz, Johanna Regulation of the immunoglobulin heavy chain locus (IgH) super-enhancer function by Spt5 is essential for antibody class switch recombination

147

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Posters A-Z

Flury, Valentin The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1

148

Foster, Ben Presenter: Jenner, Richard G. Eviction of PRC2 from specific genes by G4 RNA tethering 149

Franz, Henriette Presenter: Appiah, Bismark Histone 3 lysine 79 methylation carries information of neuronal progenitor differentiation in the CNS

150

Frost, Stephanie L Several Enhancer Regions Regulate Transcription of CCN2 151

Gao, Rui Pioneering function of Isl1 in epigenetic control of cardiomyocyte cell fate

152

Gehre, Maja Lysine 4 of H3.3 is essential for enhancer and promoter histone enrichment and ESC differentiation

153

Genevini, Paola The Diagenode Epigenetics Custom Services. Complete workflows for genome-scale DNA methylation and histone marks analysis.

154

Gil, Noa Production of spliced long noncoding RNAs specifies regions with increased enhancer activity

155

Glaser, Laura V. Assessing genome-wide dynamic changes in mESC enhancer activity during early differentiation by FAIRE-STARR-seq

156

Gohel, Priya Differential expression of POU/Oct transcription factor isoforms during the cell cycle

157

Goldshtein, Matan Rewiring of transcription factor binding in differentiating human embryonic stem cells is constrained by DNA sequence repeat symmetry

158

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Goldstein, Ido Assisted Loading – An Emerging Mechanism for Transcription Factor Cooperation and Synergistic Gene Expression

159

Gopalakrishnan, Rajaraman A conserved genetic interaction between Spt6 and Set2 regulates H3K36 methylation

160

Gowthaman, Uthra Regulators of divergent non-coding transcription 161

Greulich, Franziska COMPASS/SETD1A is involved in the anti-inflammatory actions of the Glucocorticoid Receptor

162

Gudmundsdottir, Bjorg The zinc finger protein POGZ is a part of a chromatin modifying complex that represses HBF expression.

163

Guerrero-Martinez, Jose Antonio Presenters: Guerrero-Martinez, Jose Antonio; Reyes, Jose Carlos

Genome-wide Identification of TGF-beta-dependent chromatin-enriched lncRNAs

164

Haines, Jenna Chromatin accessibility along the anterior-posterior axis of the Drosophila embryo

165

Harrold, Caroline Dissecting the role of CTCF boundary elements at the mouse a-globin locus

166

He, Yuliang Characterization of human blood vascular and lymphatic endothelial cells by single cell sequencing

167

Heikkinen, Sami Direct and indirect transcriptional regulation by TCF7L2 in Hep3B cells 168

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Posters A-Z

Hendy, Oliver Investigating genome-wide requirements of transcriptional co-factors for enhancer specificity

169

Herman, Laëtitia Genome wide exploration of the effect of FOXL2 and its partners 170

Hermand, Damien RNA Polymerase II CTD serine 2 phosphorylation regulates developmental arrest in C. elegans

171

Heyn, Patricia Presenters: Heyn, Patricia; Jackson, Andrew

Gain of function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions

172

Higashijima, Yoshiki Lysine demthylase 7A and 6A dynamically modulate chromatin looping to control inflammatory gene transcription in human endothelial cells

173

Humbert, Jonathan Role of KAT5 chromodomain in the activities and functions of the NuA4/TIP60 acetyltransferase complex

174

Iannello, Andrea 17ß-Estradiol induces an epigenetic shift from T helper 17 to T regulatory cells in vitro and in multiple sclerosis patients during pregnancy

175

Ilsley, Melissa Direct lineage reprograming to erythroid progenitors reveals factors required for definitive cell fate

176

Ing-Simmons, Elizabeth Control of chromatin conformation in the early Drosophila embryo 177

Jaensch, Elizabeth Specific roles for Cbx7 in pluripotency and differentiation 178

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Jakobsson, Johan Targeted disruption of DNMT1 in human somatic cells activates LINE-1 elements

179

Jennings, Barbara Investigating the effects of the Groucho on RNAP II pausing 180

Jia, Yanhan The role of Lamin B1 in lung cancer migration and metastasis 181

Juven-Gershon, Tamar TRF2 controls cell cycle progression and viability by modulating the expression of distinct target genes

182

Kalna, Viktoria ERG controls an endothelial-specific transcriptional program associated with super-enhancers

183

Kamieniarz-Gdula, Kinga Vertebrate PCF11 selectively controls full-length and premature transcript termination

184

Kanki, Yasuharu A novel tri-valent histone modification is necessary for the balance of angiogenesis --- accelerator and brake---

185

Kim, Ji-Hye Anticancer Effect of a New SIRT7 Inhibitor in Human Uterine Cancer MES-SA through Regulation of p53 Acetylation

186

Kindgren, Peter Presenter: Ivanov, Maxim plaNET-Seq: Native Elongating Transcript sequencing reveals dynamic RNAPII transcription in plants

187

Kolesnikova, Olga Presenter: Papai, Gabor Molecular structure of promoter-bound yeast TFIID 188

Kuijpers, Lucas Understanding the dynamics of hematopoietic differentiation 189

Kukalev, Alexander 3D chromatin landscape of the rare cell types in mouse brain 190

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Posters A-Z

Kvon, Evgeny Large-Scale Functional Dissection of a Human Enhancer In Vivo 191

Kyheröinen, Salla Nuclear actin in transcription by RNA polymerase II 192

Lamaa, Assala H2A.Z variant isoforms have independent and interdependent functions in specific genes regulation

193

Lavigne, Matthieu D. Keeping the transcribed and regulatory genome mutation-free upon genotoxic stress; A reason for activating transcription at TSSs and eTSSs

194

Lee, Jaehoon Comparative analysis of DNA methylation during seed ripening and germination in Arabidopsis

195

Leeke, Bryony Presenter: Decarpentrie, Fanny Using metatherians to elucidate the evolution of mammalian epigenetic pathways

196

Legrand, Nathalie Presenter: Adhikary, Till PPARbeta/delta regulates Mediator recruitment and reinitiation of ANGPTL4 transcription

197

Lehming, Norbert Succinylation of Histone H1 Promotes DNA Repair 198

Leidescher, Susanne The Titin gene as a model to study the spatial organization of expressed genes

199

Leopold, Karoline Presenter: Schalch, Thomas HP1 protein Chp2 regulates transcriptional gene silencing through specific interaction with nucleosome remodeler

200

Li, Lily Characterizing determinants of molecular compatibility between enhancers and promoters

201

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Li, Xinge Dissecting the enhancer-promoter interaction at MYC locus in cancer with single-cell precision

202

Liefke, Robert MTF2 and EPOP as novel players in PRC2 regulation 203

Lim, Jonathan Nuclear factor one transcription factors regulate developmental enhancers critical for cell differentiation during brain development

204

Lin, Shau-Ping Transposable Element Modulation in Germ Cells, Stem Cells and Ageing 205

Liu, Peng Role of ubiquitination and phosphorylation in modulating cell plasticity through mediating stability and stoichiometry of PRC2-Ezh1 in postmitotic cells

206

Loh, Chet Role of MTF2 in specification of meso-endodermal lineages in embryonic stem cells

207

Lonfat, Nicolas Transcriptional regulation within the retinal progenitors that produce cones and horizontal cells

208

Lux, Vanda Presenters: Veverka, Vaclav; Lux, Vanda

Unravelling dimerization of the epigenetic reader LEDGF/p75 209

Luzzi, Sara INO80-regulated chromatin checkpoint promotes early termination of mRNA synthesis

210

Malkusch, Nicole Single-molecule FRET experiments to obtain insight into the structure and dynamics of RNA polymerase II transcription initiation complex

211

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Posters A-Z

Manceau, Line Discrepancies in the transcriptional activity of the paralogue chimeric proteins, PAX3FOXO1 and PAX7FOXO1, causing phenotypic heterogeneity in Alveolar Rhabdomyosarcoma patients

212

Marasca, Federica Maternal care modulates brain plasticity and neurological outcomes in preterm infants impacting L1 driven structural variation of the neural genome.

213

Markodimitraki, Corina Simultaneous quantification of protein-DNA contacts and transcriptomes in single cells

214

Marshall, Owen Profiling chromatin states in the neuronal subtypes of the fly Mushroom Body

215

Martin, Pascal A family of negative transcription elongation factors protects the genome of Arabidopsis thaliana from transcriptional interferences

216

Mayran, Alexandre Interdependence between pioneer and non-pioneer transcription factors regulates lineage specific chromatin opening

217

McMahon, Sarah Immune Regulatory Role for NF-kB/RelA K310 Acetylation Identified In Vivo by CRISPR Knock-in Approach

218

Mechtidou, Aikaterini Profiling of histone modifications with a spike in normalization strategy in macrophages

219

Medvedeva, Yulia A. CpG traffic lights as regulators of transcription factor binding 220

Melià Alomà, Julia Dissecting the role of chromatin remodelers in inflammatory gene expression

221

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Merkenschlager, Matthias Presenter: Weiss, Felix Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation

222

Messerschmidt, Daniel M. KRAB-ZFP/TRIM28 complexes shape the heritable epigenome in mammalian embryos

223

Miguel-Escalada, Irene Human pancreatic islet 3D chromatin architecture provides insights into the genetics of type 2 diabetes

224

Mikkola, Ingvild PAX6 and the glucocorticoid receptor act synergistically to activate the MMP2 promoter

225

Mitchell, Katrina Identification of Hippo pathway target genes important for tissue growth 226

227

228

229

230

Molenaar, Thom H3.3 turnover during transcription

Montez, Miguel R-loops as putative players in the regulation of sense and antisense expression at DOG1 locus

Moreau, Kévin High resolution maps of the nuclear RNA surveillance components trafficking along the yeast genome

Saini, Keshav Unravelling the mechanism of DNA shape induced transcriptional switching by RelA

Müller, Ferenc Native transcription imaging in vivo reveals the formation and cell cycle regulation of a novel and exclusive transcription body during activation of the embryo genome

231

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Posters A-Z

Murray, Struan Sense and antisense transcription change independently in dynamic systems

232

Nadeef, Seba Role of Polycomb mediated cell memory system and epigenome plasticity in metabolic and circadian clock regulation

233

Ne, Enrico CRISPR/dCas9-mediated locus-specific proteomic analysis of the latent and active HIV promoter

234

Neumann, Heinz New tools to study lysine deacetylases. 235

Ni, Shuai RNA virus infection induces a global remodelling in the host transcripome and RNA binding activities

236

Noe Gonzalez, Melvin Transcription-coupled RNA capping: beyond the Pol II CTD 237

Oh, Sumin Differential gene regulation through functional units associated with super enhancer in cancer cells

238

Ohlendieck, Kay Concurrent mass spectrometry-based proteomic profiling of histones and the dystrophin-glycoprotein complex in skeletal muscle

239

Olan, Ioana Complex rearrangement of the enhancer-promoter network during Oncogene-induced senescence

240

Oldfield, Andrew NF-Y controls fidelity of transcription initiation at gene promoters through maintenance of the nucleosome-depleted region

241

Oliviero, Salvatore Regulation and function of DNA methylation in ESCs and EpiSCs. 242

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Oravecz, Attila Transcription factor and chromatin dynamics in interphase and mitosis 243

Oricchio, Elisa Presenter: Sungalee, Stephanie Intra-TADs structural and functional modifications in EZH2 mutated tumors

244

Östlund Farrants, Ann-Kristin The chromatin remodelling complex B-WICH is required for ribosomal transcriptional activation by glucose stimulation

245

Oudelaar, Marieke Single-allele chromatin interactions reveal regulatory hubs in dynamic compartmentalized domains

246

Paprcková, Darina The Role of Phosphoinositides in Chromatin Remodeling 247

Pardavila, Jose Angel BET Family of Proteins Influences Nuclear Reorganization During Somatic Cell Reprogramming

248

Park, Kyunghyuk DNA demethylation is initiated in the central cell of Arabidopsis 249

Patel, Nishal Genomic analysis of Hox protein binding sites 250

Pena, Rodrigo Targeting of TIP5 bromodomain has a regulatory impact of stem cell-like features in prostate cancer progenitor cells

251

Petryk, Nataliya Presenter: Andersson, Robin MCM2 counteracts asymmetric inheritance of modified histones during DNA replication

252

Pflüger, Christian A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target DNA methylation activity

253

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Posters A-Z

Picco, Giulia Identification of novel transcription factors during hematopoietic development

254

Pontis, Julien Evolutionarily recent transposable elements and their controllers regulate human early embryonic transcriptional networks

255

Porozhan, Yevheniia Experimental autoimmune encephalomyelitis as a model to study the crosstalk between autoinflammation and gene silencing

256

Pospisil, Vitek Graded PU.1 levels activate granulocyte vs. macrophage genes via multiple (super)enhancer elements.

257

Pradhananga, Sailendra Early static and dynamic Promoter-Enhancer interaction in LPS activated THP1 macrophages

258

Qu, Jieqiong EEC syndrome p63 mutations affect epidermal cell identity through rewiring the enhancer landscape

259

Rachez, Christophe Dynamic regulation of chromatin and transcription by HP1gamma protein - an RNA connection

260

Rahnamoun, Homa Mutant p53 regulates the cancer cell epigenome through interactions with the histone methyltransferase MLL4

261

Rajagopalan, Deepa TIP60 represses cellular ERV(IL)S in colorectal cancer 262

Ramos Martins, Laurène Functional Analysis of the Gremlin1 cis-Regulatory Landscape during Limb Bud Development

263

Ranjan, Amol New roles of human Mediator subunit MED26 in post-initiation regulation of RNA Pol II transcription

264

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Regadas, Isabel Presenter: Vaid, Roshan Histone 3 lysine 14 is essential and required for wing patterning in Drosophila

265

Reiter, Franziska Investigating combinatorial transcription factor requirements and the molecular events during enhancer activation.

266

Rennie, Sarah Presenter: Dalby, Maria Transcription start site analysis reveals widespread divergent transcription in D. melanogaster and core promoter-encoded enhancer activities

267

Rennie, Sarah Predicting the three-dimensional architectures underpinning regulatory decisions in development

268

Rickels, Ryan Life Without H3K4 Monomethylation on Enhancers Catalyzed by TRR/MLL3/MLL4/COMPASS

269

Rocha Viegas, Luciana Role of Glucocorticoid Receptor in cell death and differentiation in myeloid leukemia

270

Rogerson, Connor Chromatin accessibility analysis identifies an underlying HNF4A-GATA6 regulatory module in oesophageal adenocarcinoma

271

Rohrmoser, Michaela Presenters: Rohrmoser, Michaela; Eick, Dirk

MIR sequences recruit zinc finger protein ZNF768 to expressed genes 272

Rolando, Monica The Legionella pneumophila methyltransferase RomA methylates also non-histone proteins during infection

273

Rubio, Karla MIRLET7D delivery as therapeutic approach against Idiopathic Pulmonary Fibrosis

274

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Posters A-Z

Rudnizky, Sergei The bp-scale thermal diffusion of nucleosomes facilitates binding of transcription factors

275

Russo, Marta Dissecting the role of the Mediator complex in the inflammatory gene expression program in macrophages

276

Sabirov, Marat Functional redundancy of the Fab-7 boundary in the Bithorax-complex is defined by dual activity of the iab-7 Polycomb Response Element

277

Sagini, Hanan The transcription factor Hac1i is required to suppress transcription of genes via RPD3-SIN3 histone deacetylase complex

278

Saha, Debarya Aff4, a super-elongation complex member primes quiescent myoblasts for cell cycle reentry by regulating RNA polymerase II stalling

279

Saha, Parna Interplay of pericentromeric genome organization and distinct chromatin landscape regulates Drosophila heterochromatic gene expression

280

Salamon, Irene Novel transcripts involved in heart development and disease 281

Salas Bastos, Adrián Spatio-temporal adaptation of DOT1L-mediated transcriptional control during hippocampal development

282

Salbert, Gilles Hyperhydroxymethylation of the MCF-7 cell genome alters estrogen signaling

283

Sanulli, Serena A deformable histone core enables chromatin compaction and droplet formation by heterochromatin protein Swi6

284

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Sar, Pranati MHC II (DRB) promoter polymorphisms and protection against malaria in Indian population

285

Sarnataro, Sergio Transcription reactivation kinetics after mitosis 286

Sawarkar, Ritwick Stress-sensitive liquid condensate formation by pausing proteins 287

Schep, Ruben Chromatin context effects on DNA double strand break repair 288

Schick, Sandra Loss of specific mammalian BAF subunits causes global changes in chromatin accessibility and gene expression

289

Schmähling, Sigrun Function of Ash1-mediated H3K36 di-methylation and its regulation by MRG15 in the trithorax-group complex AMC

290

Schmoller, Kurt Michael Cell-size-dependent mRNA regulation coordinates histone homeostasis and cell size

291

Schwartz, Uwe Early epigenetic and transcriptional dysregulation in human lung fibroblasts in COPD

292

Schwarz, Jessica Proteins contributing to MYC‘s affinity towards promoters with and without E-boxes

293

Schwenty-Lara, Janina Methyltransferase KMT2D regulates neural crest development in Xenopus

294

Sebestyen, Endre Chromatin fractionation sequencing for the detection of early heterochromatin alterations in Hutchinson-Gilford progeria syndrome

295

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Posters A-Z

Semple, Colin Modelling double strand break susceptibility to interrogate structural variation in cancer

296

Serebreni, Leonid Identification of protein interactors at functionally distinct types of promoters

297

Sharifi Tabar, Mehdi Comparison of the composition and interaction partners of the Nucleosome Remodeling and Deacetylase (NuRD) complex stoichiometry across cancer cell lines

298

Sijm, Ayestha Substrate selection and deubiquitination by USP7 299

Sobol, Margarita A. Nuclear lipid islets are involved in the efficient RNA polymerase II transcription

300

Song, Ning Post-transcriptional regulation of iron regulatory proteins on alpha-synclein in SH-SY5Y cells

301

Song, Yun Structural and Functional Coupling Between LSD1 and HDAC1 in the CoREST Co-repressor Complex

302

Souaid, Charbel Identification and characterization of polycomb repressed gene-enhancer loops

303

Sprieto, Susana Presenter: Angevin, Lucie Roles of the Mediator kinases CDK8 and CDK19 in cell and tissue physiopathology in the mouse

304

Srivastava, Avinash Zinc finger transcription factor vGAF/ ThPOK interacts with a spectrum of functionally divergent nuclear proteins and is essential for efficient DNA repair and genomic stability

305

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Stamper, Ericca Tissue-specific enhancer and promoter evolution in mammals 306

Staneva, Desislava Characterization of putative chromatin modifiers in an ancient eukaryote 307

Stark, Alexander Presenters: Lin, Gen; Karner, Katharina M.

Assessing differential enhancer activities using genome-wide STARR-seq in human cells

308

Stark, Alexander Presenter: Nemcko, Filip A high-throughput method to identify trans-activation domains within transcription factor sequences

309

Stecher, Karin Identifying novel factors involved in the crosstalk between H3K9me3 and DNA methylation in mammals

310

Steimle, Jeffrey An evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development

311

Steiner, Florian A C. elegans model for the histone H3.3K27M cancer driver mutation 312

Stolper, Rosa Introducing an ectopic CTCF binding site causes disruption of gene expression at the alpha-globin locus

313

Sudarshan, Deepthi Chromosomal Translocations Producing EPC1-PHF1 and EPC1-ASXL2 Fusion Proteins: Oncogenic Mechanism through Mis-localization of Epigenetic Marks

314

Svensson, Peter Chromatin evolution of the HIV-1 provirus in primary resting CD4+ T cells

315

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Posters A-Z

Tacconi, Carlotta Lineage-specific epigenetic landscapes of lymphatic versus blood vascular endothelium

316

Taglini, Francesca DNMT3B is required to maintain DNA methylation at heterochromatin in cancer cells

317

Tariq, Muhammad Interplay between different chromatin modifying complexes to maintain epigenetic cell memory

318

Tatomer, Deirdre The Integrator complex cleaves nascent mRNAs to attenuate transcription

319

Teixeira da Rocha, Simão Genetic dissection of Xist lncRNA reveals independent RNA modules involved in transcriptional silencing and heterochromatin formation

320

Thakur, Ram Pairing of BET inhibitors with three generations of clinically used tyrosine kinase inhibitors enriches for malignant stem-like cells

321

Tsai, Albert Transcriptional microenvironments modulate transcription from low-affinity enhancers

322

Tufegdzic Vidakovic, Ana A single ubiquitylation site on RNA polymerase II couples DNA damage response to transcription

323

Turberfield, Anne H KDM2A and KDM2B coordinate widespread transcription repression in mouse embryonic stem cells

324

Ueberschär, Malin Developmental patterning and gene regulation by the BEN-solo protein family

325

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Umehara, Takashi JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states

326

van Bemmel, Joke Gerarda The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist

327

van Ouwerkerk, Antoinette Identification of functional variants associated with atrial fibrillation 328

van Zundert, Brigitte AJ Presenter: Sanchez, Mario Revealing different epigenetic profiles in memory-activated hippocampal neurons after context and contextual fear conditioning.

329

Vervoort, Stephin Discovery of novel regulators of transcriptional pause-release 330

Videira, Alexandre LncRNA PVT1 mediates in prostate cancer LNCaP cells the interaction between androgen receptor (AR) and Polycomb Repressive Complex 2 EZH2 Subunit in coordinating a transcriptional repression program

331

Vihervaara, Anniina Transcriptional memory to repeated stress 332

Villamil, Gabriel Trm140 installs 3-methylcytidine on tRNA arginine in S. cerevisiae 333

Villeret, Vincent Crystal structure of Human Mediator complex subunit MED23 334

Voigt, Philipp Nucleosomal Asymmetry Shapes Histone Mark Binding at Bivalent Domains

335

Wang, Jun Hypoxia-inducible factors regulation on iron metabolism in 6-OHDA treated astrocytes

336

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Posters A-Z

Waymack, Rachel Shining light on the role of shadow enhancers in transcriptional noise 337

Whisnant, Adam RNA-Mediated Shutoff of Host Gene Expression Induced by Herpes Simplex Virus Type 1

338

Whitchurch, Jonathan Functional studies on KAT6A in Mental Retardation Autosomal Dominant 32 syndrome (MRD32) using CRISPR-Cas9 genome editing

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Wolf, Elmar MYC Controls Directionality and Processivity of Transcription by Recruiting SPT5 to RNA Polymerase II

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Woodworth, Alex Understanding binding modalities of transcription factor RUNX1 341

Woringer, Maxime Investigation of the sequence determinants of c-Myc dynamics in mESC 342

Wosika, Victoria Quantitative single-cell transcription dynamics to investigate chromatin regulation of stress genes expression

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Wyck, Sarah Oxidative Stress in Sperm Affects Reprogramming in Early Embryonic Development

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Xu, Ke Temporospatial induction of homeodomain gene cut dictates natural lineage reprogramming

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Yahia, Yousra RNA Polymerase II C Terminal Domain is largely dispensable for transcription in living cells

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Yang, Lu The role of DNA methylation during haematopoiesis 347

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Yang, Shen-hsi Transcriptional regulators driving pluripotency exit 348

Yi, Jia The role of an intragenic enhancer in regulating CD44’s alternative splicing

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