Accessory Glands of Digestion

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    - well-developed branched myoepithelial cells surrounding the secretoryportion- prevents distention of the secretory end piece during secretion when

    intraluminal pressure is increased- more associated with sublingual glands4. Duct systema. Intercalated ducts- lined by squamous or low cuboidal epithelium with myoepithelialcells- originating from the acini and drain to the intralobular / striated ductsb. Striated duct

    - l ined by simple columnar (contains basal striations representing verticallyoriented mitochondria in the basal compartments for rapid ion and H2Otransport)c. Intralobular ducts-grouping of striated ductsd. Interlobular duct- initially lined by stratified cuboidal epithelium but distally linedwith stratified columnar epithelium

    e. IntralobarInterlobarf. Terminal duct (principal)

    5. Blood Supply- Rich Vascular Supply- The basal rate of blood flow to salivary glands is 20x greater than the flow ofblood to the skeletal muscle.6. Nerve Supply-ANS

    The acinus, intercalated duct and striated duct together, constitute the

    SALIVON, the functional unit of a salivary gland.Comparative Table of Major Salivary Glands

    PANCREASProduces digestive enzymes in its exocrine portion and a nin its endocrine portion (islet of langerhans)

    A. EXOCRINE PANCREAS1. Pancreatic acinar cells2. Pancreatic ducts3. Pancreatic secretionsB. ENDOCRINE PANCREAS1. Islet of langerhans2. Islet cells3. Islet hormones

    A. The exocrine pancreas is a serous compound tubulo1. PANCREATIC ACINAR CELLSa. pyramidal serous cells arranged around a central lumeb. possess a round basal nucleus, abundant rough endopl(RER), an extensive Golgi complex, numeroand many free ribosomes.c. zymogen (secretory granules)- membrane-bound and densely-packed in the pancreatic acinar cells.- contain enzymes and proenzymes packaged COMPLEX.d. basal plasmalemma has receptors for cholecystokinin a2. PANCREATIC DUCTSa. Initial intra-acinar portion of the intercalated ducts is foacinar cells, which are low cuboidal with a pale cytoplasb. INTERCALATED DUCTSINTRALOBULAR DUCTSINTERLOBULAR DUCTSMAIN (ACCESSORY) PANCREATIC DUCTC. fuses w/ THE CBD( common bile duct )AMPULLA OF VATERmajor duodenal papillaDUODENUM

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    3. connective tissue layer dense irregular collagenous connective tissue;presence of nerves and blood vessels.4. serosa covers most of the gallbladder but adventitia is present where the

    organ is attached to the liver.FUNCTION: The gallbladder concentrates, stores, and releases bile.