Abstracts

Volume 17 Number 4 October 1987

Epiluminescence microscopy of pigmented skin lesions. I 583

REFERENCES

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5. Goldman L. Some investigative studies of pigmented nevi with cutaneous microscopy. J Invest Dermatol 1951; l 6:407-26.

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7. Fritsch P, Peehlaner R. The pigment network: a new tool

for the diagnosis of pigmented lesions. J Invest Dermatol 1980;74:458.

8. Fritsch P, Pechlaner R. Differentiation of benign from malignant melanocytic lesions using incident light microscopy. In: Ackermann AB. Pathology of malignant melanoma, New York: Masson, 1981:301-12.

9. Steiner A, Pehamberger H, Wolff K. In vivo epiluminescence microscopy of pigmented skin lesions. II. Di- agnosis of small pigmented skin lesions and early detec- tion of malignant melanoma. J Am Acad Dermatol 1987; 17:584-91.

10. Ackerman AB, Mihara I. Dysplasia, dysplastie mela- nocytes, dysplastic nevi, the dysplastic nevus syndrome and the relationship between dysplastic nevi and malignant melanomas. Hum PathoI 1985;16:87-91.

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A B S T R A C T S

Lying to military physicians about risk factors for HIV infections

Potterate JJ, Phillips L, Muth JB: JAMA 1987;257:1727

A comparison of risk factor classification in 20 human immu- nodeficiency virus (HIV)-infected men interviewed first by military and later by civilian investigators revealed homosexual/bisexual 20% versus 70%, intravenous drug abusers, 5%/15%, and undetermined, 75%/15%. It is suggested that risk factors in the military personnel are not significantly different from nonmilitary individuals.

J. Graham Smith, Jr., M.D.

Isotretinoin treatment of rosacea

Turjanmaa K, Reunala T: Acta Derm Venereol (Stockh) 1987;66:89-91

Seventeen of 20 patients with severe rosacea treated with isotretinoin, 0.5-1 mg/kg/day for 3 to 6 months, had no relapse during follow-up of 1 year. All patients had good or excellent responses while on therapy.


Cryotherapy for dermatoflbromas

Lanigan SW, Robinson TWE: Clin Exp Dermatol 1987; 12:121-3

Twenty-seven patients with 35 dermatofibromas had good or excellent results in over 90% of the lesions. The patients were treated with liquid nitrogen spray to produce a visible freezing of the lesion at 2 mm border of surrounding skin for 30 seconds.


The frequency of lupus anticoagulant in systemic lupus erythematosus--a study of sixty consecutive patients by activated partial thromboplastin time, Russell viper venom time, and anticardiolipin antibody level

Petri M, Rheinschmidt M, Whiting-O'Keefe Q, Hellmann D, Corash L: Ann Intern Med 1987;106:524-31

In recent reviews, the frequency of lupus anticoagulant or related untiphospholipid antibodies in patients with systemic lupus erythematosus has varied from 21% to 65%, whereas in earlier reviews the percentage was 6% to 18%. In this study of 60 patients, lupus anticoagulant was found in 6.7% and anticardiolipin antibody assay in 25%.


The restaurant syndromes

Settipane GA: N Engl Reg Allergy Proc 1987;8:39-46

Five major factors cause restaurant syndromes: food allergens, suIfites, monosodium glutamate, tartrazine, and scombroidosis (and other seafood poisoning), Allergic reactions to food such as peanuts have produced fatalities in minutes through an IgE-mediated reaction. An extremely rapid onset within minutes after ingestion of symptoms consisting of flushing, bronchospasm, and hypotension is consistent with a sulfite reaction. Bronchospasm and urticaria in a patient with a history of aspirin intolerance suggest tartrazine sensitivity. Flushing, urticaria, pruritus, gastrointestinal complaints, or bronehospasm fol- lowing a fish meal implies scombroidosis, siguatera, or other seafood poisoning. The treatment of choice for acute reactions is epinephrine followed by an antihistamine.


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