I
(Continued from page 17)
The study included 204 women 102 case-patients and 102 control~
patients; 141(70%) were Saudi and 63 (30%) were non-Saudi. The
median age was ~ 1 years (range 15-46 years). The median week of
gestation for case~ was 12 (range 6-22 weeks); the median week of
gestation for controls was 33 (range 27-39 weeks). The me-dian
number of abortions was 1 (range 0-12); 63 % of the abortions
occurred in the first trimester and 19% occurred in the second
trimester. The median gravidity was 5 (range 1-17) and the median
parity was 4 (range 0-12). There were 10 (4.9%)stillbirth and 19
(9.3%) prenatal deaths.
Anti-HEY was positive in 22 of cases and in 9 of controls
(OR=2.8, 95%CI=1.15-7.16, P-value = 0.01). These positive HEY cases
were free
from rubella, toxoplasmosis, or any other cause of abortion.
After stratifi-cation in univariate analysis, there was a
statistically significant association between having one abortion
or more and having anti-HEY (OR=8, 95% CI=I .5-58, P-value=0.002).
. The use of IUCD as a contracep-
tIve, use of traditional medicine ha-bitual abortion, and
history of blood transfusions were statistically signifi-cant
(Table 1).
Regarding the risk factors, drinking water fro~jerry cans and
living in houses wnich reported having insects and flies, or sewage
leaks in the area were associated with having anti-HEY, while
households which em-ployed servants were protected against having
HEY (Table 2).
-Reported by: Shadia E. AI-Soudani Dr. Nasser A. AI-Hamdan, Dr.
R. E. '
~able ~. Univariate analysis of selected variables that lead to
abor-tion, Riyadh, 1995
Cases Controls (Aborted) (Pregnant)
Variables Exp. NotExp. Exp. NotExp. OR 95%CI P-value
Contraceptive use IUCO 20 82 7 95 3.3 1.2-9 0.007 oral 32 70 36
66 0.84 0.4-1.5 0.5
Traditional medicine 46 56 22 80 3 1.5-5 0.0003
Habitual abortion 22 80 6 96 4 1.5-12 0.001
Blood transfusion 15 87 6 96 2.7 0.94-8.4 0.03
T~ble2. Risl< factors associated with having HEY among
pregnant women Riyadh, 1995 '
Cases Controls (aborted) (pregnant)
Risk Factors HEY+ HEY- HEY+ HEY- OR 95%CI Drinl
Hepatitis E
(Continlledjrom page /8)
drinking water must not be bought from unmonitored stations and
em-phasize the importance of proper han-dling and storage of
water.
References: 1. Skidmore SJ , Yarbough PO,
Gabor KA, Reyes GR. Hepati-tis E virus the cause of a
wa-terbourne hepatitis outbreak. Journal of Medical Virology
1992;37:58-60.
2. Tsega.E, Hansson BG, Krawczynski K, Nordenfelt E. Acute
sporadic viral hepatitis in Ethiopia: Causes, risk fac-tors and
effects on pregnancy. Clinical Infectious Diseases 1992;
14:961-5.
3. Khuroo MS, Kamili S, Jameel S. Vertical transmission of
hepatitis E virus. Lancet 1995;345:1025-6.
4. Arif M, Qattan I, Alfaleh F, Ramia S. Epidemiology of
hepatitis E virus (HEV) infec-tion in Saudi Arabia. Annals of
Tropical Medicine and Parasi-tology. 1994; 88(2): 163-8.
5. Ritter A, Flacke H, Vornwald A, Zaaijer H, Seed AA, Daw-son
G, Simpson B, Sutherland R. Aseroprevalence study of hepatitis E in
Europe and the Middle East. Journal of viral heptitis and liver
disease. 1994;432-4.
Saudi Epidemiology Bulletin, Vol 6, No 3,1 999
Mark you lendar ...
Outside the Kingdom
Sep.7-10~2000: 38th Annual Meeting of the Infectious Diseases
Society of America, New Orleans, USA. Contact: IDSA Customer
Service at (800)375-25-2586 , Fax (617)876-5351 or E-mail:
[email protected].
Oct.23-25, 2000: 5th lEA Eastern Mediterranean Regional
scientific Meeting, Bahrin. Contact: Conference Sec., PO Box 22118,
Bahrain. Phone: (+973)246341, fax (+973)258221, E-mail:
[email protected], Web site: http://zurba.com/conf/iea5.
Oct,29-Nov.2,2000: 49th Annual Meeting, American Society of
Tropical Medicine and Hygiene, Washington, DC, USA. Contact: ASTMH,
60 Revere Dr., Suite 500, Northbrook, IL 60062 USA. Phone: (847)
480-9592, Fax: (847) 480-9282, E-mail: [email protected] or
www.astmh.org. Online submission: http:
//abstract.comtser.com/.
(Continued/rampage 21) Measurment of personal cost of illness
due to some major water-related diseases in an Indian rural
population. Int J Epidemiol 1990; 19(1): 169-176.
2. Eesrey SA, Collett J, Miliotis MD, Koornhoof HJ, Makhale P.
the risk of infection from Giardia lambia due to drinking water
sup-ply, use of water, and latrines among preschool ch ildren in
rural Lesotho. Int J Epidemiol1989;18 (1 ):284-52.
3. Feachem Rg, Bradley OJ, Ga-relick H, Mara DO. Sanitation and
disease: Health aspects of ex-creta and waste water
manage-ment(world bank studies in water supply and sanitation. New
York: John wiley & sons, 1983;173-78.
Send correspondence, comments, calendar listings or articles
to:
Saudi Epidemiology Bulletin Editor-in-Chief
. P.O. Box 6344 Riyadh 11442, Saudi Arabia
UFor epidemiological assistance, call or fax the FETP at
01 -496-0163, . e-mail: [email protected]
The Saudi Epidemiology Bulletin welcomes reports from the
re-gions. Please send your reports to the address shown. Thank
you.
Saudi Epidemiology Bulletin (SEB) is published quarterly by the
Department of Preventive Medicine and the Field Epidemiology
Training Program (FETP) of the Ministry of Health.
Department of Preventive Medicine: Dr. Yagoub AI-Mazroa
Assistant Deputy Minister for Preventive Medicine, and SEB
Supervisor
Dr. Mohammed AI-Jefri General Director, Parasitic and Infectious
Diseases Department
Dr. Amin Mishkas Director, Infectious Diseases Department
Field Epidemiology lraining Program: Dr. Nasser AI-Hamdan,
FETP
Super,risor, SEB Editor-in-Chief Dr. Tajammal Mustafa
Consultant Epidemiologist Dr. Mohammed A. AI Mazroa
Assistant Supervisor, FETP Dr. Haya AI Eid and Ms. Linda W.
Dobbs,
SEB Editors
Page 23
